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  • Articles  (28)
  • PNAS Profiles  (28)
  • National Academy of Sciences  (28)
  • Blackwell Publishing Ltd
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  • International Union of Crystallography
  • Periodicals Archive Online (PAO)
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  • 2010-2014  (28)
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  • Articles  (28)
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  • National Academy of Sciences  (28)
  • Blackwell Publishing Ltd
  • Elsevier
  • International Union of Crystallography
  • Periodicals Archive Online (PAO)
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  • 2010-2014  (28)
  • 1995-1999
  • 1960-1964
  • 1950-1954
  • 1940-1944
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  • Natural Sciences in General  (28)
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  • 1
    Publication Date: 2011-06-22
    Description: Charles Sawyers is a rock star in his own right. Last year, Sawyers, chair of the Human Oncology and Pathogenesis Program at Memorial Sloan–Kettering Cancer Center and a member of the National Academy of Sciences, posed with singer Debbie Harry of the rock band Blondie to promote cancer research in a campaign sponsored by the Geoffrey Beene Cancer Research Center. The unlikely assemblage of rock star and researcher shined the spotlight on pioneering efforts in translational cancer research. Few physicians deserve that spotlight more than Sawyers, who co-discovered the targeted cancer drug, Gleevec, forging a path to cancer treatment that...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
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  • 2
    Publication Date: 2011-05-04
    Description: Neal R. Amundson (born 1916), Cullen Professor Emeritus of Chemical and Biomolecular Engineering and Professor of Mathematics at the University of Houston, died February 16, 2011 in Houston at the age of 95.pnas;108/18/7285/UNFIG01F1unfig01Neal R. Amundson. Image courtesy of the University of Houston.There have been many descriptors of Amundson—transformational figure, father of modern chemical engineering, the preeminent chemical engineer in the history of the United States, and most prominent and influential engineering educator in the United States. For those of us with roots at the University of Minnesota, he will continue to be known as the Chief. Neal Amundson played a...
    Keywords: PNAS Profiles
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
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  • 3
    Publication Date: 2011-06-01
    Description: Within the confines of remote Chaco Canyon, large Pueblo great houses stand sentry among smaller dwellings, the palatial behemoths unoccupied and the nature of their growth and decline 1,000 years ago in this region of the American Southwest still under debate. In his Inaugural Article, archaeologist Stephen Plog, elected to the National Academy of Sciences in 2007, uses evidence from burials within one of these great houses to assert that these societies were not as egalitarian as their more modern Pueblo counterparts are, but that they supported a social hierarchy (1). The dead can, and do, tell tales, yet with...
    Keywords: PNAS Profiles
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  • 4
    Publication Date: 2011-11-09
    Description: Saul Roseman (born 1921) was the Ralph S. O'Connor Professor of Biology, Emeritus, at The Johns Hopkins University. He died of congestive heart failure on July 2, 2011 at the age of 90.pnas;108/45/18219/UNFIG01F1unfig01Saul Roseman.Roseman was born in Brooklyn and received his bachelor's degree in Chemistry from the City College of New York (CCNY) in 1941, one of a remarkable number of scientists of his generation to receive their science training at CCNY. He began graduate training in Biochemistry at the University of Wisconsin only to have it interrupted by service in the infantry in Europe in World War II, also...
    Keywords: PNAS Profiles
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  • 5
    Publication Date: 2011-11-16
    Description: In 2001, half a decade after researchers announced the arrival of Dolly, the first mammal cloned from an adult somatic stem cell, scientists in the private sector decided to clone a pet cat. A couple of years later the enterprise went commercial, and eager pet owners lined up for the service. However, disappointment inevitably ensued: although the clones were genetically identical to the original pets, cloned cats often looked and acted nothing like their predecessors. Michael Grunstein, were he so inclined, might have said, “I told you so.” Grunstein, a distinguished professor of biological chemistry at the University of California,...
    Keywords: PNAS Profiles
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  • 6
    Publication Date: 2011-11-23
    Description: Lennart Philipson was a monumental person with an impressive stature, a charismatic personality, and an intellect of high caliber. He was a born leader, and his accomplishments as a scientist and director of research institutions are breathtaking. Lennart was born in Stockholm and went to medical school at Uppsala University. Although he had a license to practice, his clinical experience was minimal and instead, science caught his interest. In 1958, he defended his PhD thesis, which dealt with respiratory viruses. He then stayed in Uppsala and started to interact with the department of biochemistry, which at the time, was headed...
    Keywords: PNAS Profiles
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  • 7
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    National Academy of Sciences
    Publication Date: 2011-11-23
    Description: In the mid-1970s, breast cancer survival rates were dismal. Researchers hoped to find a drug capable of thwarting the disease, but the prospects were few and far between. In a laboratory on the campus of the Worcester Foundation for Experimental Biology in Shrewsbury, Massachusetts, a group of experimental rats were dying from breast cancer. A researcher gave them a triphenyl ethylene—a purported antiestrogen—with the slim hope that it would slow progression of the disease. The cancer disappeared (1). Within a few years, a clinical trial of the drug was launched among women suffering from breast cancer. The women's tumors, just...
    Keywords: PNAS Profiles
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  • 8
    Publication Date: 2011-11-30
    Description: Eugene Patrick Kennedy died peacefully at his Cambridge home, age 92 years, on September 22, 2011. He was a giant of 20th century biochemistry, and his pioneering studies of lipid biosynthesis and function were a foundation of modern cell biology. He was also a man of immense intellect and genuine modesty, a devoted teacher who inspired his many students and colleagues, and a loving father, grandfather, and friend.Gene was born September 4, 1919, the fourth of five children of Irish immigrant parents. His early formal education was in the Catholic schools of Chicago, but his real education was from the...
    Keywords: PNAS Profiles
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  • 9
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    National Academy of Sciences
    Publication Date: 2011-11-30
    Description: Days after Tak Mak and colleagues (1) revealed a way that cancer cells adapt to environmental stress, the immunologist and his team announced the discovery of a protein that may cause heart failure (2). The two breakthroughs were all in a week's work for Mak, director of The Campbell Family Institute for Breast Cancer Research at the Princess Margaret Hospital in Toronto, Ontario, Canada. Throughout the course of his career, Mak has contributed to over 700 papers, received more than 65,000 citations in leading scientific journals, and garnered numerous prestigious international awards. In 2002, he became a foreign associate of...
    Keywords: PNAS Profiles
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  • 10
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    National Academy of Sciences
    Publication Date: 2011-11-30
    Description: A world without forests would challenge life on earth. Forests maintain biodiversity, influence the climate, and regulate the water cycle, says Eric Lambin, a professor of earth sciences at Stanford University and a recently elected member of the National Academy of Sciences. However, as the world's population swells, forest loss accelerates. To feed the world's growing population, it will be necessary to clear an estimated 2.7–4.9 million hectares of cropland per year, even while expanding urban centers shrink the available land by 1.6–3.3 million hectares per year (1).pnas;108/48/19127/UNFIG01F1unfig01Eric F. Lambin.pnas;108/48/19127/UNFIG02F2unfig02Land use variations in the highlands of Vietnam. Courtesy of Patrick...
    Keywords: PNAS Profiles
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