ISSN:
1420-9071
Keywords:
Drosophila melanogaster
;
intercalating mutagens
;
crossing-over
;
clastogenic activity
;
recombination induction
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary In order to evaluate the effect of several intercalating compounds on crossing-over inDrosophila melanogaster females, acridine orange, acriflavine, chloroquine, ethidium bromide and quinacrine were fed separately to larvae ofy ct f/+++ genotype. Our results show that acridine orange, acriflavine and ethidium bromide increase significantly the recombination frequency at thect-f region and support the view that, for intercalating agents, there is a relationship between clastogenic activity and female recombination induction.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01952152
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