ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
Filter
  • Artikel  (107)
  • Column liquid chromatography  (107)
  • Springer  (107)
  • American Association for the Advancement of Science
  • American Meteorological Society
  • Blackwell Publishers Ltd
  • Springer Nature
  • 2010-2014
  • 2000-2004
  • 1995-1999  (107)
  • 1980-1984
  • 1955-1959
  • 1940-1944
  • 1935-1939
  • 1930-1934
  • 2002
  • 1998  (107)
  • 1943
  • 1937
  • Chemie und Pharmazie  (107)
  • Wirtschaftswissenschaften
  • Mathematik
  • Allgemeine Naturwissenschaft
  • Geologie und Paläontologie
Sammlung
  • Artikel  (107)
Datenquelle
Schlagwörter
Verlag/Herausgeber
  • Springer  (107)
  • American Association for the Advancement of Science
  • American Meteorological Society
  • Blackwell Publishers Ltd
  • Springer Nature
Erscheinungszeitraum
  • 2010-2014
  • 2000-2004
  • 1995-1999  (107)
  • 1980-1984
  • 1955-1959
    • +
Jahr
Thema
  • Chemie und Pharmazie  (107)
  • Wirtschaftswissenschaften
  • Mathematik
  • Allgemeine Naturwissenschaft
  • Geologie und Paläontologie
  • 1
    Digitale Medien
    Digitale Medien
    Application of SPE for the HPLC analysis of taxanes fromTaxus cell cultures (1998)
    Springer
    Chromatographia 47 (1998), S. 25-34 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Solid Phase Extraction ; RP-HPLC gradient analysis ; Taxus Cell Cultures ; Taxol and Taxanes
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary Solid phase extraction (SPE) methods are studied for the sample pretreatment for HPLC analysis ofTaxus cell suspension cultures. Various types of SPE materials were tested for the extraction of both the taxane standards and samples of various origin. Comparison between the different cartridges and the different elution solvents are made in terms of extraction recovery and sample clean-up. Selective elution of the taxanes is achieved by a gradient elution scheme.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02466782
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 2
    Digitale Medien
    Digitale Medien
    Ionic strength dependence of heavy metal tartrate complex stabilities (1998)
    Springer
    Chromatographia 47 (1998), S. 77-80 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Ion chromatography ; Stability constants ; Ionic strength ; Heavy metals ; Tartaric acid
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary Ion chromatography and potentiometry were used for the determination of the stability constants Pb, Zn, Co, Ni, Mn tartrate complexes at different ionic strengths. An extrapolation function based on the Debye-Hückel equation was applied to obtain the thermodynamic stability constants.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02466789
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 3
    Digitale Medien
    Digitale Medien
    Development of an Ion-pair HPLC method for the determination of 2,4- and 2,6-toluendiamine in human plasma (1998)
    Springer
    Chromatographia 47 (1998), S. 84-88 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Ion-pair LC ; Plasma ; 2,4-Toluendiamine ; 2,6-Toluendiamine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary An ion-pair HPLC method is presented for the determination in plasma of 2,4- and 2,6-toluendiamine (TDA), known carcinogens. The chromatographic conditions consisted in isocratic elution on a reversed phase C18 column with 5 mM octanesulfonic acid in methanol-water, 45∶55, as mobile phase. UV detection was performed at 235 nm. Samples were analyzed after a simple single step liquid-liquid extraction and the method was validated by measurement of precision (interassay and intraassay), sensitivity, specificity, linearity, and recovery. The detection limit for both TDAs in plasma was 20 ng mL−1. The correlation coefficients based on the intrassay calibration curve were 0.998 and 0.997 for 2,6- and 2,4-TDA, respectively. The intraassay accuracy, expressed in terms of recovery, was found to be up to 89.91% and 97.05% for 2,6- and 2,4-TDA, respectively.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02466791
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 4
    Digitale Medien
    Digitale Medien
    Direct resolution of a new antifungal agent, voriconazole (UK-109,496) and its potential impurities, by use of coupled achiral-chiral high-performance liquid chromatography (1998)
    Springer
    Chromatographia 47 (1998), S. 649-654 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Enantiomer separation ; Voriconazole (UK-109,496) ; Effect of organic mobile-phase modifier
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary Coupled achiral-chiral high-performance liquid chromatography (HPLC) with an achiral amino-based column coupled with a chiral amylose-based column has been used for qualitative and quantitative determination of the potential chiral and achiral impurities of Voriconazole (UK-109,496), a new antifungal agent with two stereogenic centres. The effect of the organic mobile-phase modifier, ethanol, was studied. The assay response was linearly dependent on concentration over the range 1.2–40.4 μg for Voriconazole and 2.5–104.0 ng for the impurities. The limit of detection was 2.5 ng for each analyte.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02467448
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 5
    Digitale Medien
    Digitale Medien
    Separation of inorganic anions and cations on titania by use of acetic acid-sodium acetate and bicine-sodium hydroxide buffers (1998)
    Springer
    Chromatographia 47 (1998), S. 655-658 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Ion chromatography ; Titania packings ; Inorganic anions and cations
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary The ion-exchange retention behavior of titania synthesized in our laboratory was investigated by ion chromatography of inorganic anions and cations. Dilute acetic acid-sodium acetate and bicine-sodium hydroxide buffers were used as mobile phases with no use of suppresor. We observed that the titania, although poor at separating monovalent anions expcept nitrite ion in this experiment, was both an anion and a cation exchanger, and selectively retained fluoride and carbonate ions. We concluded that because of its specific retention properties there were possibilites of using this amphoteric exchanger for simultaneous analysis of anions and cations, and of using it as a selective packing material for ion chromatography.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02467449
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 6
    Digitale Medien
    Digitale Medien
    Retention behavior of morphine and its metabolites on a porous graphitic carbon column (1998)
    Springer
    Chromatographia 47 (1998), S. 667-672 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Porous graphitic carbon ; Optimization ; Morphine and metabolites
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary The chromatographic behaviour of a series of morphine-based opiates has been investigated using a porous graphitic carbon packing material at acid and alkaline pH. The effects of mobile phase pH, mobile phase organic percentage, column temperature and ionpairing agents were studied. All six opiates were separated within a close retention window despite large differences in measured lipophilicities of the individual opiates. The retention order was not related to the log P values of the opiates and strong retention of the fully ionised compounds was observed, particularly those with acidic functional groups. The effect of pH on the retention of the compounds indicated that the degree of ionisation of the individual compounds was important in the separation mechanism, suggesting that hydrophobic interactions were present in addition to the polar retentive effects observed above. The strong retention of the ionised glucuronide and sulphate conjugates of morphine is a particularly useful feature of the porous graphitic carbon packing material which has general applicability to the analysis of polar or ionised drug metabolites.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02467451
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 7
    Digitale Medien
    Digitale Medien
    Determination of clozapine in human plasma by solid-phase extraction and liquid chromatography with amperometric detection (1998)
    Springer
    Chromatographia 47 (1998), S. 8-12 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Amperometric detection ; Solid-phase extraction ; Plasma ; Clozapine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary A sensitive and selective high-performance liquid chromatographic method has been developed for monitoring clozapine levels in human plasma. Chromatography was performed on a reversed-phase column (C8, 150 mm×4.6 mm i.d., 5 μm) with acetonitrile-aqueous sodium acetate solution, 88∶12 (v/v), as mobile phase; the flow rate was 1 mL min−1. Clozapine oxidation at +800 mV was detected amperometrically. Response was linearly dependent on concentration over the range 50–1500 ng mL−1 clozapine in plasma. Sample preparation by solid-phase extraction before HPLC analysis gave high extraction yield (94%). The accuracy and precision of the method were both very good (recovery: 97%;RSD〈3.3%).
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02466779
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 8
    Digitale Medien
    Digitale Medien
    Characterization of the precolumn bio trap 500 C18 for direct injection of plasma samples in a column-switching system (1998)
    Springer
    Chromatographia 47 (1998), S. 299-304 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Plasma samples ; Direct injection ; Restricted-access media ; Column-switching
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary A new restricted access media (RAM) type of precolumn, Bio Trap 500 C18, for direct injection of plasma samples in column-switching systems was evaluated with respect to the elution of plasma proteins in different mobile phases, the loading capacity of plasma samples, the chromatographic behavior during plasma injections and protein contamination of the packing and sealings. More than 95% of plasma proteins could be excluded from the precolumn within three minutes for all selected mobile phases. Quantitative analyte recoveries could be obtained by injecting plasma samples ranging from 5 to 500 μL with the analyte mass〉150 ng onto a BioTrap 500 C18 column (20×4 mm I.D.). One precolumn tolerated about 15 mL of plasma injection without out noticeable change in retention and pressure. Clogging of the precolumn was encountered (≥45 mL of plasma) due mainly to the adsorption of proteins on the packing. The performance of the analytical column (Kromasil C18) was also examined. The column efficiency decreased by 60% after processing 45 mL plasma in total.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02466535
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 9
    Digitale Medien
    Digitale Medien
    Characterisation of pitch by HPLC (1998)
    Springer
    Chromatographia 47 (1998), S. 373-382 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Polyaromatic hydrocarbons ; Pitch
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary A new high performance liquid chromatography method for the characterisation of toluene-soluble fractions of pitches has been developed. Although a chromatographic system typical of size exclusion chromatography was used, results indicate that, for these structurally complex samples, separation does not follow the usual discrimination by molecular size. A differentiation between several classes of polyaromatic hydrocarbons is achieved instead. Data are reported on the analysis of individual standard polyaromatic hydrocarbons, showing that four different elution ranges can be observed: three ofcata-condensed compounds (Cata1, Cata2 and Cata3) and one ofperi-condensed compounds (Peri). Results are reported proving the capacity of this high performance liquid chromatography method to distinguish between pitches of different origin and nature. It is also effective for the study of the chemical reactions occurring during heat treatment.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02466467
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
  • 10
    Digitale Medien
    Digitale Medien
    Determination of the five major opium alkaloids by reversed-phase high-performance liquid chromatography on a base-deactivated stationary phase (1998)
    Springer
    Chromatographia 47 (1998), S. 21-24 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Opium alkaloids ; Papaver somniferum L.
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary A reversed phase HPLC method for the separation of the five major alkaloids fromPapaver somniferum L., morphine, codeine, thebaine, papaverine and noscapine, has been developed and validated. By use of a basedeactivated silica-based stationary phase excellent peak shape was achieved for each substance. The five alkaloids were quantified by internal standardization within 20 min and with good precision. The method is applicable to opium and to poppy straw.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02466781
    Standort Signatur Erwartet Verfügbarkeit
    BibTip Andere fanden auch interessant ...
    Artikel (Nationallizenzen)
    Volltext
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...