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  • Life and Medical Sciences  (189)
  • 1980-1984
  • 1940-1944
  • 1930-1934  (189)
  • 1910-1914
  • 1934  (100)
  • 1933  (89)
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  • 1980-1984
  • 1940-1944
  • 1930-1934  (189)
  • 1910-1914
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  • 1
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: By means of the ‘intravitam technic’ developed by Baumgartner and Payne (1931), the mature or maturing sperm of Chortophaga viridifasciata have been traced from the follicle of the testes in the male to the locus of fertilization in the female. The sperm aggregated into bundles, and held tight by a hyaline cytoplasmic cap, spiral up the follicle, turn and spiral back to the vas deferens by means of a periodic lashing and writhing of the sperm tails.The genital tract is described briefly. In the vasa deferentia and storage tubules, the sperm bundles are usually in a quiescent state, having been inactivated most probably by secretions from the tubules.Peristalsis and currents in the fluid contents of the tubules move the inactivated sperm from the vesicles of the male to the seminal receptacle of the female, where the cytoplasmic caps gradually disintegrate. This permits individual sperm to pass down the seminal duct and fertilize the ovum just before oviposition.Single photomicrographs and a series of photomicrographs show the sperm in various parts of the genital system and making actual progress up a follicle. A stained preparation was used for only one of the photos. The other nineteen are from living unstained tissue. The intravitam observations are, most probably, more ‘vital’ than any heretofore recorded.
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 54 (1933) 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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  • 3
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This investigation was undertaken to determine some of the variables involved in the demonstration of the Golgi elements. Gland cells of vertebrates were studied vitally, after impregnation by osmic acid methods, and after autolysis.The duration of the staining period and the concentration of the stain condition the results obtained by vital staining with neutral red. The success of impregnation of Golgi elements with osmic acid varies with,(1) the type of tissue, (2) the time of initial fixation in relation to the time of the death of the animal, (3) the position of the cell in the piece of tissue, and, (4) the temperature of incubation with osmic acid. Stages in the impregnation of Golgi elements can be followed by examining preparations of the same tissue at frequent intervals during the incubation period. An increase in the amount of material which reduces osmic acid and which may form Golgi elements occurs in the cells during autolysis.The results are interpreted as indicating that Golgi elements are visible products of chemical reactions that occur in cells. They represent localized regions containing particular classes of chemical compounds which may be present, as such, in living cells or result from transformations in the cells during incubation. It is suggested that for the cells under consideration these substances may be unsaturated fatty acids.
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  • 4
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 54 (1933), S. 399-413 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The m. trapezius, with both brachial and branchial functions, is in seeming series with the mm. interarcuales laterales. The intrinsic muscles of the fin occur as a dorsal extensor sheet and three (or four) ventral flexor components. The spinal nerves, uncomplicated by extensive anastomoses, which supply the fin, clearly show that in the dogfish the fin muscles are derived not from dorsal and ventral elements, but from anterior and posterior, or protractor and retractor elements. The nerves prove that from the original protractor musculature only the anterior portion of the present flexor group is derived, while the original retractor musculature has become all of the extensor and the posterior part of the flexor series. Faradic stimulation of the live animal is satisfactory, although there is much variation in the sensitivity, particularly of different muscles.
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  • 5
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 54 (1933), S. 477-491 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The mitochondria in the male germ cells of Sciara exhibit peculiarities as regards both morphological characteristics and distribution. In form. they show superficial similarity with those of some of the scorpions, while their distribution may be peculiar to the genus and depend on unusual meiotic divisions.
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  • 6
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 54 (1933), S. 459-475 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A description of the urogenital system in both sexes of Lepidosteus platystomus Rafinesque, and new observations on the blood supply to this system as well as to the rest of the viscera is given.The testes resemble the true piscine type. The sperm are carried by numerous vasa efferentia to the kidney tubules, through the mesonephros to the wolffian duct, and to the exterior as in the elasmobranchs and amphibians. The most anterior of the vasa efferentia are non-functional. The ovaries are simple sac-like structures continuous with their ducts. The oviducts transverse the ventro-lateral surface of the mesonephros, and enter into the dilated portions of the wolffian ducts, where they join, directly anterior to the urogenital aperture. There are no ducts in the male homologous with the oviducts of the female. The kidneys fused posteriorly, appear to extend the entire length of the body cavity, but the anterior third is non-urinary.By injection methods, the celiaco-mesenteric artery is shown to be crowded to the posterior end of the body cavity by the complicated swim-bladder, and runs anteriorly to supply the entire viscera. Its anterior portion is incorporated in the liver.
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  • 7
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1933) 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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  • 8
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1933), S. 29-51 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This article is an account of the complete musculature of an adult Neuropteran insect, Chrysopa plorabunda. Previous anatomical discussions on this order of insects include only a few of the muscles of the head and thoracic regions, while those of the abdomen are entirely lacking. The muscles here described include those of the head, thorax, and abdomen. The origin, insertion, and function of each muscle is given. The boundaries of several of the sclerites, especially those of the labium, are located by the observations on the musculature of these parts. The meso- and metathoracic wings are of the same size and for that reason the muscles of these regions are very much alike. The prothorax is greatly elonated, causing the muscles of that region to differ to a greater or less degree from the ‘general rule’ in insects. The abdominal muscles may be arranged in the several groups generally found in insects. In several cases, however, both the origin and insertion of the muscle have been shifted to accompany changes which have taken place in the abdominal segmentation. All of the muscles are shown in the four plates containing nineteen figures which accompany the text.
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  • 9
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1933), S. 131-135 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Photomicrographs have been made of grasshopper spermatocytes using ultraviolet light of several wave lengths. For studying chromosomes this wave length should be between ca 2800 A and ca 2500 A. With higher frequencies the entire cell becomes strongly absorbing and relatively little detail is to be seen. All cell structures, including the chromosomes, are as transparent to λ = 3500 A and to longer ultraviolet waves as they are to visible light. The present experiments do not indicate the exact point between λ = 3500 A and λ = 2800 A at which the selective chromatin absorption commences.
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  • 10
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This investigation consists of an extensive histological study of a special strain of abnormal x-rayed mice, in an attempt to determine the embryonic origin and development of certain congenital abnormalities that are hereditary.The study shows that development of the x-rayed strain is normal up to the thirteenth day after insemination, after which pathological structures appear in the form of blebs, hematomas, and thrombi. As a result of the formation of the blebs and hematomas a general condition is set up within the embryo which resembles that of thrombosis. The thrombi when formed exert a mechanical effect by crowding out the normal tissue. A chemical effect is also produced by the blood cells and fluid extravasated from the thrombus which penetrate into the forming tissues resulting in their perverted development. Thus the thrombi are the immediate factors causing the various regions of the body to be deformed.
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  • 11
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1933), S. 207-251 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The Goodeidae are a family of cyprinodonts containing about nine genera and twenty-six species. They are confined exclusively to the Mexican Plateau and to streams in the immediate vicinity. All are viviparous. Fertilization is internal. The eggs are extremely small and contain very little yolk. The embryos are retained in the ovarian follicles until the yolk is practically absorbed, in the meantime developing unique absorptive organs in the form of extensive ribbon-shaped proctodaeal processes. The embryos are evacuated into the intra-ovarian cavity where they are retained for several weeks, during which time the proctodaeal processes become extended. The ovary becomes a nutritive organ and produces secretions which are discharged into the intra-ovarian cavity and absorbed by the embryo through their unique processes. The processes differ in form, number, and histological structure, but are specific in their peculiarities for each species. These specific differences, together with marked differences in the ovary, will furnish a basis for a re-classification of the genera and species of the family. A comparison in made between this family and the other ovo-viviparous and viviparous cyprinodonts, on the basis of which it is concluded that the Goodeidae have arisen separately from an ovo-viviparous ancestor, which in turn was derived from an ovo-viviparous type. A comparison is also made between the peculiarities of reproduction in this family and those of other viviparous teleosts.
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  • 12
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1933), S. 349-385 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Lead poisoning causes a selective destruction of mature erythrocytes, thereby depleting the spleen and stimulating differentiation and proliferation of erythrocytes in the blood. In conjunction with splenectomy, this intravascular erythropoiesis is markedly accelerated.During the progressive anemia and subsequent regeneration of erythrocytes in simple lead poisoning the major hemopoietic loci, spleen, mesonephros, liver, and epicardium were observed. The spleen is most rapidly affected. The red cell progenitor first present in the circulation is the hemoblast, but later numerous lymphocytes enter the blood stream and are transformed into erythrocytes.Following simple splenectomy the blood shows relatively little change. A mild regenerative activity of both erythrocytes and thrombocytes ensues. In lead poisoning after splenectomy the blood picture resembles that of simple lead poisoning. The anemia is produced more rapidly and the regeneration of erythrocytes is delayed.This study emphasizes the importance of the blood stream of Necturus as a site of red cell differentiation and proliferation, and shows that the lymphocyte may be a possible progenitor of erythrocytes and thrombocytes. Under normal conditions the hemoblast suffices as a source for red cells, but under abnormal or experimental conditions, where the demand for new cells is excessive and prolonged, the lymphocyte plays a major role.
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  • 13
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Each indifferent genital rudiment in the grasshopper embryo is composed of the following: (1) a terminal filament membrane; (2) an epithelial plate of indifferent cells, the dorsal cell mass; (3) the central cell mass containing germ and indifferent cells; (4) the ventral cell strand, and, (5) a delicate, investing membrane, the outer limiting membrane. It is roughly spindle-shaped in transverse section and extends from the first to the eighth abdominal segments.In the sexual differentiation of the genital rudiment the dorsal cell mass is retained as a definite embryonic rudiment in the female, but becomes an indistinguishable part of the central cell mass in the male.Ovarian development is initiated in the dorsal cell mass area, where cell aggregations are formed. Each aggregation is ultimately surrounded by the ingrowing outer limiting membrane to form distinct cellular columns. A latero-ventrad extension of this ingrowing process into the central cell mass continues the column formation process into the latter and results in the formation of a distally tapering structure composed of indifferent cells distad and germ cells and indifferent cells proximad. This structure constitutes the rudimentary ovariole which finally differentiates to form the terminal filament, germarium, and vitellarium.The ovarian portion of the oviduct and the tubular connection between the ovariole and oviduct are differentiated from the ventral cell strand.
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  • 14
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 55 (1934), S. 611-631 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This paper describes the cellular relations between the prechordal mesoderm and the hypophyseal analage in duck embryos from the first to the eighth day of incubation.At nineteen somites the ectoderm destined to form hypophysis is seen as a plate of cells lying under the mesodermal mass anterior to the notochord. It extends anteriorly in intimate contact with the base of the forebrain, and posteriorly for about the same distance to the oral membrane. Following the lateral growth of the prechordal mesoderm and the rapid overgrowth of the forebrain, Rathke's pouch is definitely outlined. The upward expansion of the pouch, concomitant with the lagging of some of the prechordal mesoderm in the midline, effects a very close relation between these cells and those at the tip of the pouch. With the lateral expansion of the premandibular head cavities, some of the mesoderm adheres to walls of Rathke's pouch in the form of rods or knobs. As development proceeds the inherent growth tendencies of ectoderm and mesoderm express themselves differently and the rods or knobs become constricted off from the pouch, forming in its vicinity vesicles which exhibit a definite lumen.The question of an entodermal contribution to the hypophysis in this form is briefly considered.
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  • 15
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    New York, NY : Wiley-Blackwell
    Journal of Morphology 56 (1934), S. 51-58 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: By treating the clean skeletal tissue of an insect with concentrated KOH at 160° C., the contained chitin is converted to chitosan, and all pigmentation and admixtures are removed. The per cent distribution of chitin, expressed as chitosan, in the exoskeleton of the cockroach, Periplaneta fuliginosa, ranges from 37.65 in the dorsal abdomen to 18.22 in the hindwings. Other regions contain the following per cents: ventral abdomen, 37.11; metathoracic legs, 35.55; mesothoracic legs, 33.28; prothoracic legs, 32.24; pronotum, 31.55; head, 31.07; genitalia, 29.28; dorsal thorax, 29.07; ventral thorax, 28.33; antennae, 27.77; cerci, 25.65; and forewings, 19.99. Regional variations are constant in different individuals of the same species. The crop and gizzard contain 18.69 per cent; the hindgut, 18.15 per cent. The remainder of the alimentary tract contains no chitin. Traces of chitin are found in the trachea. No chitin is found in the egg-cases of this species. No correlation between chitin content and pigmentation or hardness is shown. Based on results from three trials, using thirty insects, the per cent of chitosan in the clean, dry chitinous material from the entire animal is 29.60; the per cent of chitosan based on the weight of the live animal averages 2.01.
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  • 16
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    Journal of Morphology 54 (1933), S. 233-258 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The fundamental structure of the brain stem is uniform throughout the vertebrate series, not essentially because it expresses an architypical pattern, but because of the constancy of peripheral connections and their internal relationships, both of which are parts of an apparatus of adjustment to environment which is common to vertebrates. Other parts of the brain are more variable because, with complication of the behavior pattern in higher forms, more elaborate and diversified mechanisms of correlation and integration are requisite.The brain stem between the olfactory bulb and other primary sensory centers is plastic tissue not dominated by any single sensory-motor system; it is the meeting place of descending and ascending sensory paths. Here the chief apparatus of correlation and integration is elaborated. From it emerge the complex thalamic and cortical adjustors. The pallium is not a primary constituent of the vertebrate brain. The pallial type of organization gradually emerged from the more ancient subpallial type and comes to mature expression in the cerebral cortex. Several instructive stages in the progressive differentiation of cortical structure and connections are seen in the amphibian forebrain, but the process is not consummated. Amphibia have no cerebral cortex, though cortical primordia are evident here and in various fishes. Static concepts of architypes and the dialectic of ‘form-analytic’ argumentation are replaced by a more dynamic treatment of morphogenesis.
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  • 17
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    Journal of Morphology 54 (1933), S. 347-363 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: From a mating of first-cousins, of whom the female had cataract, there issued in four generations a progeny of 138 individuals, 33 of whom had cataract (23.8 per cent). Discounting the last generation, about which little is known, also discounting other unknown members, there were 29 known unaffected, 30 known affected, i.e., 50.8 per cent had cataract. The pedigree by generations shows that cataract is inherited as an autosomal (Mendelian) dominant. However, the mode of inheritance is atypical in that the defective gene for cataract may be borne, and is so borne because transmitted, without producing in the bearer its characteristic defect. In the second generation there were four of a family of nine with cataract; of the five without cataract two produced cataractous offspring and three did not marry. The literature is replete with pedigrees in which cataract is inherited as a typical autosomal dominant; there are a few pedigrees (four are reproduced) in which the mode of inheritance, while distinctly that of an autosomal dominant, resembles the present pedigree in being atypical. It is concluded that cataract is inherited as an autosomal dominant, but that in some cases it is produced only under certain conditions. These conditions are as yet not definitely known. Clinical writers seem to favor the view that nutritional and endocrine disturbances predispose to the realization of the defect.
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  • 18
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    Journal of Morphology 54 (1933), S. 365-388 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A histological study of Hammond's simple recessive ‘furless’ rabbits was made from many series of sections taken from the skin of both the normal and furless rabbits of several pertinent ages.It was found that the external absence of under-hair or fur exists because of a failure of the hairs of these follicles to erupt. This failure is due to a premature keratinization which first affects the sebaceous glands and then the inner epithelial sheath. The resulting abnormal channel allows an erratic escape, especially of the regenerating hair above the incomplete inner sheath into the surrounding connective tissue, where the escaped part of the hair atrophies. The final condition shows an inflammatory reaction in the areolar tissue here. There is no check on the growth from the bulb of the root. Other elements of the skin verify this excessive keratinization.The cause of the abnormal metabolic changes conceivably lies in an inadequate tissue supply of oxygen or nutrition. The regulator may be the sympathetic system directly or indirectly (by hormone action), or it may be an inhibitor resident in the integument itself.
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  • 19
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The anatomical isolation of the auricles from the ventricle in hearts of fresh-water mussels representing nine North American species has been confirmed. The muscle fibers in these hearts without exceptions were found to be of the smooth, unstriated type. Bundles of these fibers loosely interwoven, form the thin, delicate, heart wall, which contains many sinus-like spaces. The outside portion of the heart wall exposed to the pericardial fluid is covered with a definite epicardium composed of a single, dense layer of epithelial and scattering mucous cells. The inside of the heart cavity has no endocardium, the muscle fibers being in direct contact with the blood. No special conduction tissue, nerves or ganglia were found in the heart wall. Correlations of these anatomical and histological findings with the physiological reactions of the living heart in situ are made, and the mechanical and chemical control of the heart discussed.
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  • 20
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    Journal of Morphology 56 (1934), S. 325-337 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The purpose of this study was to learn something of the nature of the bead-like bodies which occur in the head of the sperm of the fowl since it was found in a previous study that they are apparently affected in a characteristic manner by vitamin E deficiency.Staining tests indicate that these bodies are composed of fats and fatty acids since they respond to osmic acid and Nile blue sulphate. They are also impregnated with silver nitrate and hence may be associated with the so-called Golgi materials of the cell.The beads first appear as a complete single row but subsequently they undergo fragmentation and redistribution. The whole process is probably a final transitory step in sperm transformation.The presence of this fatty material may signify that the sperm of the fowl, in contrast to that of most other animals, carries a store of food material to support its activity after liberation. The sperm may also be the carrier of a definite amount of vitamin E. Furthermore, the presence of this material may offer an explanation of the high resistance of the testis of the fowl to vitamin E deficiency because, since this vitamin is fat soluble, the testis as a whole would probably receive a disproportionately large share of the vitamin E stores of the individual.
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  • 21
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In sections from livers injected through the vascular system with Carter's carminegelatin or Berlin-blue gelatin masses at known, constant pressures, many cells were observed to contain ovoid or spherical bodies of the colored injection masses, similar to those described by Schäfer and his students, Herring and Simpson, as intracellular blood canaliculi.' In these livers practically all the cells were vacuolated. However, with livers injected with Berlin-blue gelatin mass dissolved in Locke's solution instead of distilled water, there were no intracellular masses and the cells appeared normal, though the sinusoids were completely filled with injection mass. The so-called ‘intracellular blood canaliculi’ described by Schäfer are interpreted as artefacts produced by a combination of factors, the most important of which is the difference in osmotic pressure. This is produced by the hypotonicity of the injection masses that are usually used, augmented perhaps by the effect of mechanical pressure used in administering the injection mass.Following impregnation of liver tissue by Golgi's rapid method, the usual network of intercellular bile canaliculi was revealed, but the presence of a permanent system of intracellular canaliculi was not observed. A few short, knobbed intracellular projections from the intercellular bile canaliculi were noticed; these probably represent the passage of secretion material into the intercellular bile canaliculi at the moment of excretion.
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  • 22
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The early developmental history of Sciuridae (squirrel family), from the ovarian egg to the establishment of the germ layers, was studied in fixed material comprising ova and embryos from six species of five genera. No significant differences were noted in the major processes of development in the six species. Continuous diminution in the size of the ova occurs from the beginning of follicular vesiculation up to the early blastocyst stages. Corpora haemorrhagica are present in most of the recently ruptured follicles of all the species.Cleavage is regular, though adequal, up to the eight-cell stage, the blastomeres clustering into a compact mass. There is desquamation of cellular material from the periphery of the ovum between morula and blastocyst stages. At the same time cells within the blastocyst degenerate to add to the cavity originally formed by confluence of intercellular spaces. The cavity forms among the inner cells, an inner cell mass being left at one pole and an anti-embryonic mass at the other. The anti-embryonic cells produce much of the yolk-sac entoderm and contribute to the implantation mass. The latter mass forms a temporary attachment of the blastocyst to the uterine mucosa in these species. The definitive entoderm arises by migration and delamination of certain of the inner cell mass cells. A transitory notochordal canal, passing in a vertical plane through Hensen's node, is strongly suggested.
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  • 23
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    Journal of Morphology 56 (1934), S. 533-575 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The arterial system of Ptyas mucosus (Linn.) reveals the following interesting features: (1) A prominent diverticulum given off from the inner antero-dorsal edge of the left auricle. (2) Ridge-like continuation of the median hanging valve of the sinus venosus lining the ventral edge of the opening of the right precaval vein. (3) Guarding of the opening of the pulmonary vein by a portion of the inter-auricular septum abutting against it. (4) Presence of two longitudinal trunks on either side of the hepatic portal vein formed by the hepatic branches of the hepato-oesophageal arteries, which, uniting with one another, form a peculiar arrangement looking almost like a looped chain. (5) A complete arterial circuit in the female formed by the combination of the genital, supra-renal, and the anterior-most renal arteries of either side. (6) Chain-like arrangement formed by the alternate bifurcation and union of the posterior-most part of the longitudinal fat-body artery and also by its lateral branches, which unite with it here and there after giving off twigs to the fat bodies. (7) A pair of small arteries (or in some cases only one) called ‘arteria complexa’ which take their origin from the dorsal aorta opposite the openings of the iliac veins into the afferent renals.
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  • 24
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    Journal of Morphology 55 (1934), S. 577-609 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: An investigation has been conducted to ascertain the relationship of certain structures in the embryo of the grasshopper known as Melanoplus differentialis with reproductive organs in the adult male.The order of development of these structures was traced through the entire life history.It was determined that they are the rudiments of certain reproductive organs and that the knowledge obtained serves as an aid in more accurately classifying insects.
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  • 25
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The segregation of the germ cells is related in time and differentiation to the ectoderm (ventral plate), the inner germ-band layer (lower layer) and the mesenteron (entoderm) rudiments. The inner germ-band layer is formed by invagination of cells from a median blastoporic groove and by cellular proliferations among the invaginating cells and from the median line of the ectoderm immediately caudad of the blastoporic groove. The mesenteron material is derived from inner germ-band layer material associated with the internal ends of the stomodaeum and proctodaeum. The germ cells are segregated from the lateral margins of the abdominal lobe ectoderm in the region of the amnion attachment as segmentation of the abdominal lobe is initiated. They ultimately become separated from the ectoderm cells of the lateral wall and from the amnion and migrate in a passive manner onto the coelomic sacs where they become associated with the inner walls of the sacs. When the coelomic sacs unite the germ cells and the splanchnic wall mesoderm cells form two continuous cell strands from the first to the eighth abdominal segments, inclusive. These strands form the indifferent genital rudiments. An endeavor is made to correlate the segregation of the germ cells in the grasshopper with that of various other insects.
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  • 26
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    Journal of Morphology 56 (1934) 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
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  • 27
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    Journal of Morphology 56 (1934), S. 21-49 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The literature relating to the flexor and adductor muscles of the thigh and their nerve supplies, in Sphenodon, the lizards, crocodiles and mammals was correlated and new dissections made of animals belonging to the last three groups. All of these muscles can be traced as individual entities from animal to animal without loss or addition to their number, although splitting may occur. The attachments of the muscles and their relationships to one another and to the two heads of the gastrocnemius are the same in all the reptiles studied. In the mammals one group, including the adductor longus and magnus and the retractor femoralis, has migrated from the tibia between the two heads of the gastrocnemius onto the femur, and another from the ilium onto the vertebrae, the one migration being caused by expansion of the gastrocnemius, and the other by expansion of the gluteal muscles. A new lateral flexor mass has been formed from part of the reptilian ilio tibialis by migration down the fibula. The nerve supplies of the various muscles are not constant when traced from group to group, and it is suggested that a muscle receives its nerve supply from the nerve nearest to it in embryonic development, so that when a muscle has migrated the nerve supply is no longer a reliable guide to its homology.
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  • 28
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Histological studies of testes of both immature and mature individuals show that the peritoneal epithelium does not give up its proliferative capacities with the completion of testis differentiation. Certain regions of the antimesorchial surface retain their activity and continue to contribute cellular elements during testis growth. Stromal cells, germ cells, and sections of or entire seminiferous tubules originate from the peritoneum in the form of cord-like ingrowths. In this form, the proliferations of the germinal epithelium of the testes are similar to and homologous with the continuous proliferations of the germinal epithelium of the ovary.In Sternotherus, both testis and ovary differentiate out of a bisexual primordium in which the deeper parts of the germinal epithelium form an ovarian cortex. Since the germinal epithelium persists as an active part of both ovary and testis, it must be responsive to the same physiological factors of female or male differentiation respectively. It is indifferent sexually and once the direction of sex differentiation is established, the response of the germinal epithelium is in the determined direction. Its activity is then to produce either seminiferous tubules or ovarian follicles, and is directly dependent upon the processes of embryonic sex differentiation and determination.
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  • 29
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    Journal of Morphology 56 (1934), S. 295-323 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The primordia of the thymus bodies in Necturus begin to form in 7-mm. embryos. These structures arise as clumps of entodermal cells on the posterior dorsal portion of the first four visceral pouches; the first or last pouch, being rudimentary, fails to form such a primordium. All except the first of these primordia lose their connection with their respective pouches in the 16-mm. stage and lie free in the surrounding connective tissue. The primordium on the first pouch begins to show degenerative changes during that stage, losing connection with its pouch in the 23-mm. stage, finally to disappear altogether in 30-mm. specimens.The three remaining bodies continue to grow, but the second and third outstrip the fourth in development and begin to form Hassall's corpuscles in 32- to 34-mm. stages. Sections of 30-mm. Necturi show a few of these corpuscles fairly well developed and containing a faintly staining secretion. The fourth body remains relatively small a long time, not showing the Hassallian cysts until the animal is 60 mm. long. By shifting of positions and increasing in size, the three bodies come to lie in proximity, one behind the other, to form the definitive thymus gland of the adult. The gland lies embedded in the heavy musculature on top of the head in front of the gills.
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  • 30
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    Journal of Morphology 56 (1934), S. 339-359 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The effects of vitamin E deficiency in the fowl were observed in Rhode Island Red males over a period of approximately 2 years.Mating experiments showed that after 1 year on the E-free diet all of the males were capable of fertilizing ova, but that after 2 years some of the males were sterile.Sperm smears showed that shortly after the beginning of the experiment, many of the mature spermatozoa exhibited an abnormal condition of the nuclear material of the head, while others remained normal.In histological sections of the testes made at the end of the 2 years, conditions varied from almost normal to complete atrophy, the latter being a condition that has already been described in the male mammal. Moreover, the conditions in any given section were not uniform for even in an advanced stage of E deficiency there were small islands of apparently normal tissue. However, in this case, as in the mammal, the process of degeneration affects the mature sperm cells first and gradually works to the outside of the seminiferous tubule thus attacking the youngest maturation stages last.The results of the experiment point definitely to destruction of the testis under prolonged E-deficient conditions but it is also quite apparent that the testis of the fowl is extremely resistant to vitamin E deficiency.
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  • 31
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This paper is an attempt to clear up the confusion concerning the osteological relationships among the Haplomous fishes.The osteology of Novumbra hubbsi was worked out by the dissection of numerous specimens. The various skeletal features found were compared with the osteology of Umbra limi, U. pygmaea, U. crameri, and Dallia pectoralis.A description of each skeletal element of Novumbra was made, followed by a description of the chief differences between it and the same structures in Umbra and in Dallia. No constant osteological differences were found between Umbra limi and U. pygmaea, and very few between these two species and Umbra crameri. Novumbra and Umbra have more in common with each other than either does with Dallia or Esox. The presence of postorbitals, postcranials, and the shape of the secondary shoulder girdle in Novumbra show it to be also closely related to Dallia and Esox.The relationships of the various forms are summarized in a synoptic key which lists the following groups: Order Haplomi. Superfamily I, Dallioidea; Family Dallidae; Genus and species, Dallia pectoralis. Superfamily II, Umbroidea; Family 1, Umbridae; Genus and species, Umbra limi, U. pygmaea and U. crameri; Family 2, Novumbridae; Genus and species, Novumbra hubbsi. Superfamily III, Esocoidea; Family Esocidae; Genus, Esox.
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  • 32
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    Journal of Morphology 56 (1934), S. 445-475 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: This paper deals with the morphology of all the so-called gustatory and olfactory organs of blowflies, and describes tests conducted to determine whether these insects taste with their tarsi and smell with their antennae and palpi. Antennae bear two types of so-called olfactory hairs, while palpi bear only one. With the aid of an olfactometer it has been shown that antennae and palpi do not bear the olfactory organs.In order to explain the proboscis response, described by Minnich, it is not necessary to assume that tarsi bear gustatory organs, because: (1) a tarus bears no sense organs, except nine olfactory pores; (2) it is almost impossible to wet the tarsi with water or sugar water; and (3) when flies were in the proper nutritive condition and liquids were about 3 mm. from the tarsi, the insects were induced by a special method to exhibit the proboscis response. It was further clearly demonstrated by a similar method that tarsi can easily distinguish between chemically pure saccharose water and distilled water when these liquids are about 3 mm. from the tarsi. The responses, obtained by any method, are caused by two stimuli, one mechanical and the other olfactory. The act of touching the feet produces the initial stimulus and brings the liquids almost in contact with the olfactory pores on the tarsi.
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  • 33
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    Journal of Morphology 56 (1934), S. 513-531 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: A study of the male reproductive organs of a hemipteron, Leptocoris trivittatus, has been made. The genital system, which consists of fan-shaped testes; the vasa deferentia, to which a single pair of accessory glands are attached; ejaculatory ducts and the copulatory apparatus, is described and photomicrographs of consecutive parts presented.Then an analysis of the method of aggregation and turning of the sperms is made by means of intravitam technic. Aggregation and turning commence in the early spermatid stage. A spherical cyst forms, the tails first grow centripetally and then push out toward the lower end of the cyst. This line of growth in the cyst moves the head ends of the spermatids to the upper end where aggregation gradually takes place.The cysts spiral up and across the follicles, the moving force being, probably, the elongating tails. Later they spiral down the follicle, development progressing rapidly. The descending bundles are mature sperm, held together by a cytoplasmic cap.The accessory gland secretes a milky substance which probably activates the sperm at a later stage. Peristalsis occurs in the wall of the gland and duct.The process of massing sperm into bundles before copulation insures effective translocation. Then peristalsis and movement of tubular fluids carry the sperm down the duct to the copulatory apparatus.
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  • 34
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    Journal of Morphology 55 (1934), S. 421-433 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Paramecium caudatum was studied by micro-incineration, by stained control sections, by vital staining, and by osmic impregnation. It was found that a slow initial heating and a slow cooling after incineration greatly reduce the amount of distortion and shrinkage in the incinerated specimens. Most of the cytoplasmic components and organelles, including vacuome, chondriome, cilia, and basal granules, trichocysts, food vacuoles, and the nuclei, could be identified by their ash. No ash is found in the pellicle and only a small amount in the hyaloplasm. None of the osmiophilic components such as granules or the walls of the contractile vacuole could be identified in the incinerated specimens with certainty. The larger amount of ash in the endoplasm as compared with the ectoplasm is due to the large number of granules in the former region. The nucleus and some of the granules near the nucleus show traces of iron.
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  • 35
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: When sexually mature Procotyla fluviatilis Leidy (commonly but erroneously known as Dendrocoelum lacteum) are cut transversely into head, pharyngeal, and tail pieces of about equal length, the head and pharyngeal pieces fail to regenerate in a large percentage of cases and tail pieces never regenerate. When regeneration occurs in head and pharyngeal pieces it is somewhat slower than in similar pieces of Planaria maculata Leidy and Planaria agilis Stringer with which comparisons were made. Cutting mature Procotyla into larger numbers of pieces usually results in death of all, although smaller pieces from prepharyngeal regions sometimes regenerate. Juvenile P. fluviatilis have greater powers of regeneration, as shown by cutting head and pharyngeal regions into greater numbers of pieces, but tail pieces do not regenerate. These observations confirm and extend those of earlier investigators. Such a restricted power of regeneration contrasts with well-known powers in P. maculata and P. agilis. Counts of formative cells, from which new parts arise in all three species and which are regarded by the authors as a persistent embryonic stock, indicate about 8.5 such cells in P. maculata to 1 in P. fluviatilis per unit area. It is concluded that regeneration in planarians is correlated with numbers of such formative cells and that histological factors are no less important than physiological ones. The paper is preliminary to a study of effects of x-rays upon regeneration.
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  • 36
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    Journal of Morphology 55 (1934), S. 435-475 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The centrioles are recognized early in the prophase of the primary spermatocyte. They soon become double and migrate around the nucleus in opposite directions. As this is completed the nuclear membrane breaks down and spindle fibers appear. The centrioles divide in the metaphase at a time when the centrosome is still perfectly spherical. The centrosome divides in the anaphase, giving the two centers for the second division. The centriole disappears in the spermatid and cannot be seen in later stages. The behavior of the centers during the spermatocyte divisions is strikingly like that of the egg centers and other types of mitoses. Therefore, it is concluded that the centrioles of the spermatocytes are not to be regarded as different from the centrioles in other types of mitoses.The Golgi bodies increase in number and size during the growth period of the cell. They are usually found in the shape of rings. From these rings are produced the refringent granules which fuse in the late spermatid to form those of the mature sperm. It is therefore concluded that this process represents the formation of the acrosome. The mitochondria show little change during the maturation divisions. In the late spermatid they aggregate around the nucleus and become vesiculated. This is interpreted as the formation of the prenebenkern.
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  • 37
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    Journal of Morphology 56 (1934), S. 621-635 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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  • 38
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Topics: Biology , Medicine
    Notes: Observations of earlier workers concerning the limited region from which anterior regeneration will occur in Tubifex and the reduced number of segments formed were confirmed in control worms used in these experiments. Only three anterior segments are replaced when as many as twelve are removed. Regeneration is completed within 18 days.Removal of anterior segments from worms that have received 9000 (r) units exposure to x-rays is not followed by regeneration. The wound heals rapidly and worms have been kept in laboratory 70 days without further change. Longitudinal sect ons of injured ends show that the epidermis and muscle layers extend across the wound surface to completely close the body cavity. The intestine retracts slightly and heals to form a blind tube. No mitotic figures appear in cells of this region and there is no evidence of regeneration.In control worms material for formation of the cerebral ganglia and new epidermis arises by proliferation of epidermal cells. The new pharynx arises from the region of the old intestine adjacent to the wound surface. The muscle layers of the body wall and pharynx in new segments are apparently formed by migration of cells from the old muscle elements about the margin of the wound area. No neoblasts were observed in anterior migration or in the process of formation upon adjacent septa in any of the worms.
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  • 39
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    Journal of Morphology 54 (1933) 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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  • 40
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    Journal of Morphology 54 (1933), S. 429-449 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The rudimentary copulatory organ of chickens was first observed as a phallic knob in 6-day embryos. This phallic knob enlarged similarly in both male and female embryos up to the twelfth day: from the twelfth to the seventeenth day it was distinguished by a large process in the males and a diminishing process in the females. Further differentiation took place from the eighteenth to the twenty-first days: some females lacked the porcess, others retained a smaller process than that of the male. As growth advance, fewer females retained the process until at 12 weeks of age it had entirely disappeared. The process was found in all males and showed no retrogression, whereas the few capons examined lacked it. A ridge-shaped ‘pseudo’ process developed at about 1 week in some females and was present up to 3 weeks of age. Histologically and embryologically, the process was seen to possess some characteristics of a penis. The cloacal method of sex determination might be used with an average maximum accuracy of about 90 per cent in living day-old chicks.
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  • 41
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    Journal of Morphology 54 (1933), S. 521-547 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The sex cycles of a chimpanzee were studied for 18 months, during which the animal matured, menstruated four times, conceived, and delivered.Pronounced swelling of the ano-genital region appeared periodically prior to the first menstruation. During menstrual cycles the swelling endured during most of the period between flows. Genital swelling was always accompanied by estrus; copulation and insemination never occurred during its absence.The animal was alert and active when in estrus, demonstrated non-sexual affection for the male just prior to the flow, and appeared to be physically distressed during the first days of each flow.There were periodic weight changes coordinated with the animal's menstrual cycles.During pregnancy menstruation ceased, but genital swelling, with accompanying sexual receptivity, continued in irregular cycles.Cyclic changes in the desquamation of the vaginal epithelium occurred during menstrual cycles, were absent during pregnancy.The gestation period was approximately 246 days. At death from puerperal sepsis, 15 days after delivery, the ovaries were in a restin stage, one of them bearing a degenerating corpus luteum.The evidence given indicates that sex-skin swelling and estrus are similarly controlled, but may occur independently of menstruation, cornification of the vaginal epithelium, or ovulation.
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  • 42
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    Journal of Morphology 55 (1933), S. 1-13 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The molluscan genus Indoplanorbis is shown to differ markedly from all other members of the family Planorbidae in the generative complex, the vas deferens being encased in a long, flexible tube in which it is freely movable. The preputium of the male complex is shown to be completely evertible from the male opening and to act as a male copulatory organ. The presence of a single, heavy penial retractor innervated by an equally strong nerve is indicated. Comparisons are made with the genitalia of the European Coretus and the American Helisoma showing fundamental differences in the generative apparatus of the three groups. Indoplanorbis is most closely related to Coretus, the vas deferens of that group being also encased in a tube. Helisoma differs from both of these genera, the vas deferens not being encased in a tube and is of the same diameter throughout its length.
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  • 43
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    Journal of Morphology 55 (1933), S. 119-129 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The vascular channels and sinuses of this trematode contain three varieties of cells: eosinophilic granulocytes, primitive hemocytoblasts (‘amebocytes’), and modified hemocytoblasts. The latter suggest a specialized blood corpuscle, but represent apparently only a stage in the dissolution of intravascular hemocytoblasts. These ‘corpuscles’ have the form of flattened lenticular discs, approximately 12 μ in diameter. The eosinophils differentiate extravascularly from hemocytoblasts. The hemocytoblasts are in part free parenchymal cells, in part they arise from a bilaterally paired ‘lymphogenous organ’ or ‘blood island’ associated with the lateral vascular channels at the level where the ceca diverge from the esophagus.
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  • 44
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    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Nyctotherus cordiformis and Opalinids infesting Rana pipiens were studied by microincineration and in stained control sections. A marked difference in concentration and distribution of mineral salts was noted within saprozoic and holozoic organisms. The endoplasm in the saprozoic protozoa was free from inorganic residue except for the ‘vegetative’ granules; the protoplasm of the holozoic infusorians consisted of a fine network of mineral salts. Detailed examinations suggested that the qualitative and quantitative differences might be correlated with diffusion of digestible material through the cuticle. The inorganic residue of the walls of vacuoles was relatively rich in iron.
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  • 45
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    Journal of Morphology 54 (1933), S. 451-457 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Recent and fossil fishes may be divided into groups having both pectoral and pelvic fins, pectorals only, pelvics only, or with a second pair of fins located anteriorly and seemingly not homologous with pelvics. In some groups the pelvics are located near the cloaca, with an extensive hiatus between the pectoral and pelvic neuromeres; other groups are of an intermediate character, while in a third group the second pair of fins appears to have no relationship to the pelvics. The character of the innervation indicates that they could hardly have been derived from the latter, and the few nerves, consecutive with the brachial plexus, which supply them suggest origin from the posterior elements of the dermal series, the anterior of which became the pectoral fins. Instances even occur (Polynemus) in which a third pair of appendages has been derived from the original pectoral complex.
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  • 46
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    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The authors are preparing a table for the normal developments of the guinea-pig. This paper deals with the external form and the development of the external characteristics of guinea-pigs between 21 days and 35 days, copulation age. About one hundred embryos were used from thirty-six litters.Length and weight are good criteria for determining age, although there is some variation. The flexures, the disappearance of the tail, the development of hair follicles at specific locations, the degree of development of the mouth and external ear are better criteria for the determination of age.At 27 days there is a sudden increase in both weight and length. This increase is rather uniform from this period until the end of 35 days. At this time the embryo has the appearance of a newborn guinea-pig.
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  • 47
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Basophiilic granule cells which occur in vast number in the connective tissue throughout all regions of the alimentary canal of sockeye salmon and speckled trout are interpreted as histogenous mast cells. Their occurrence in several other species is noted. None could be found in blood or in any other organs. Their development from mesenchymal cells is described (speckled trout). Their function or possible relationship to functional conditions of the tract could not be determined. Experiments showed the granules to be quickly destroyed by acids and bases but not by water in the fresh condition, but they were extremely stable structures after Helly fixation. In living cells, the granules are probably fluid, and consist of proteins. There was no indication of the granules being composed of mucin, or of the cells being degenerated forms. The granules are basophilic at all times.
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  • 48
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    Journal of Morphology 55 (1933), S. 81-118 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The development of the interatrial septum and the relation of the sinus venosus and sino-atrial valves to the interatrial septum was followed in chick hearts ranging from 50 hours of incubation to the adult. The following singificant facts were established. The interatrial septum first appears at about 50 to 55 hours of incubation. It fuses with the endocardial cushions of the atrio-ventricular canal, typically in the last quarter of the fifth day. Secondary perforations appear in the septum at the time of closure of the interatrial foramen primum. These are retained until hatching, although they may persist in the adult heart. The sinus venosus, a sinus septum, and the sino-atrial valves are retained as definite structures in the adult fowl heart. The pulmonary vein and the left precava as they enter the heart form a prominent addition to the inter-atrial septum proper which I have designated as the pars cavo-pulmonalis. The pulmonary orifice in the left atrium is provided with an extensive flap-like valve. A prominent limbus of Vieussens is present in the right atrium. A well-developed median muscular arch overlies the interatrial septum and a pair of lateral muoscular arches extend over the atria. Their position would seem to be significant in the closing septal perforations during atrial systole.
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  • 49
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    Notes: The alignment and condition of mitochondria in the epithelial cells indicate that secretion is apparently the chief function of the midgut and the attached caeca. In view of the response of these cells to vital dyes, and to various fixatives, other cell structures-particularly vacuoles-are uncertain evidence of cell activities. Many structures visible by means of vital dyes indicate changes in the permeability of the cell membrane, and subsequently in the cytoplasm. Hence, they are artifacts, just as truly as those found in fixed tissue.
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  • 50
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    Journal of Morphology 55 (1933), S. 137-149 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Notes: Mid-dorsal protective hair-shafts from forty-five species of Soricidae were studied with the object of investigating the relation between the differences in certain microscopic structural elements and the diameters of the shafts in which they were developed, and the possible occurrence of specific characters in these elements. In comparing like portions of like hair-shafts, it was found that scale- and medulla-forms were related (with slight variations within their form-groups) to the diameters of the hair-shafts in which they were developed. It is possible that further study of these slight variations may show them to be associated with the species bearing the hair.
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    Journal of Morphology 55 (1933) 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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  • 52
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    Journal of Morphology 55 (1933), S. 253-263 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Notes: A survey of biological literature of the present reveals a tendency to turn to the study of the living cells and tissues. This tendency is indicated by the use of microdissection, ultraviolet microscopes, transparent chambers in rabbits' ears, growing nerve cells and fibers in tailfins of amphibian larvae, and by intravitam technic on insect germ cells. The division stages of the germ cells of Anasa tristis which were carefully studied and drawn thirty-odd years ago are now shown by actual unretouched photomicrographs. These photomicrographs confirm the drawings in many points and show other structures such as mitochondria even more clearly than the drawings do. An account of a peculiarly shaped spermatozoon which has not been described heretofore in the literature is added. The question of the great variations of shapes of spermatozoa is discussed. The advantages of the use of methods for studying living cells, especially of intravitam technic, is emphasized.
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    Journal of Morphology 55 (1934) 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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  • 54
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    Journal of Morphology 56 (1934), S. 125-155 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Notes: The chromosomes of D. melanogaster have been followed through the entire cycle of mitosis in ganglion cells. Primary constrictions exist at about the middle of the second and third chromosomes, at a sub-median position in the Y, at a sub-terminal in the X, and probably also at a sub-terminal position in the fourth chromosome. Secondary constrictions, in addition to those reported by Bridges, are sub-terminal in the arms of the second and third chromosomes. A pronounced sub-median secondary constriction in the left limb of the second chromosome offers a criterion for distinguishing between the second and third chromosomes, and between right and left arms of the second chromosome. The proximal secondary constriction in the X-chromosome and that in the short arm of the Y are associated with the normal development of the nucleolus. Anaphase chromosomes are longitudinally double, the split following the turns of the chromonemata. Metaphase and anaphase chromosomes are essentially isodiametric from end to end, except at the constrictions or indentures. Somatic pairing of chromosomes reaches its maximum expression during late prophases, both in male and female ganglion cells. The four chromatids of the tightly appressed homologues open out in two planes giving distinct chiasma-like configurations. Separation of the paired chromosomes is completed in late prophase, so that at metaphase the homologous chromosomes are not in contact.
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  • 55
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    Notes: The cytology of corpora lutea of non-pregnant ewes is described with reference to the origin, structure, fate, and function of these organs. The lutein cells, characteristic of corpora lutea, are derived from the cells of the stratum granulosum of the Graafian follicle; connective-tissue cells, embryonic cells, and non-striated muscle cells, from the theca interna; and erythrocytes, leucocytes, and histiocytes, from the blood stream. The lutein cells undergo changes in size, nuclear structure, and cytoplasmic inclusions correlated with the period in the estrous cycle and disappear during retrogression. Although secretory products have not been identified, a secretory function is postulated on the basis of the structure of the cell.
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    Journal of Morphology 56 (1934), S. 231-241 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Notes: The three species of Trichonympha found in Zootermopsis angusticollis were studied by micro-incineration, by control sections, and by Macallum's methods for iron and calcium. The mineral ash is concentrated in the neuromotor system, chromatin, nuclear membrane, the posterior end where ingestion takes place, and in cytoplasmic granules. Micro-incineration and Macallum's Prussian blue method reveal iron in the chromatin alone; Macallum's haematoxylin gives a positive test for iron in the chromatin, rostrum, neuromotor fibrils, etc. It probably is not as specific as the other methods. The two staining methods give negative tests for iron except after acid hydrolysis. Calcium is present in the chromatin, neuromotor system, posterior region of the body, and in many endoplasmic granules. The localization of calcium is correlated with the localization of normally gelated regions.
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  • 57
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    Journal of Morphology 56 (1934) 
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    Journal of Morphology 56 (1934), S. 213-229 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Notes: The conspicuous intracellular fibers (figures of Eberth) which are present in the basal epidermal cells of Rana pipiens and Rana clamitans tadpoles are thought to be connective tissue branches from the corium. They are not believed to represent fused mitochondria as concluded by Saguchi ('13). Their probable function is to furnish support to the basal epidermal cells and to strengthen the connection of the epithelial layer to the corium.It is believed that fully developed tadpole skin, before the period of metamorphosis has begun, consists of only two layers of cells, although there may appear to be more. Each of these layers is believed to be self-maintaining by mitotic division within the individual layer. The basal layer apparently does not furnish cells to the outer layer, nor was any evidence found that the outer layer is sloughed during the larval period.
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  • 59
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    Journal of Morphology 56 (1934), S. 267-293 
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    Notes: The results of recent investigations concerning caste determination among termites have been briefly reviewed with emphasis upon the work of Thompson ('17). From examination of new data upon the development of Reticulitermes arenincola Goellner, R. flavipes (Kollar), and R. tibialis Banks, and of Thompson's original R. flavipes material, I am unable to substantiate her claim that the sterile and reproductive castes are separable into two distinct groups at the time of hatching. I could distinguish them first in stadium three and suggest that the second stadium may be a critical period in differentiation. From evidence to date, it must be granted that both intrinsic and extrinsic factors may play a role in the production of castes. The delay in appearance of demonstrable caste differences until the third stadium in the genus Reticulitermes at least admits of an opportunity for extrinsic factors to be effective. Growth and metamorphosis of various structures which ultimately lead to the three differentiated castes have been followed through successive stadia. Gynandromorphs and intercastes among social insects give indication of the physiological and genetic factors influencing both morphological and behavior differences among castes.
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    Journal of Morphology 54 (1933), S. 593-615 
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    Notes: The nuclear changes involved in the two maturation divisions of G. japonicus have been studied in considerable detail. All observations compel a telosynaptic interpretation. The duality, an apparent parasynapsis, as seen beginning from synizesis up to diplotene is a result of a longitudinal splitting of the chromosomes joined end to end. Strepsinema is brought about by breaking up of the diplotene thread into segments, which really are pairs of synaptic mates in end-to-end union; each segment then bends at its middle to form V- or ring-tetrads. There are altogether twenty tetrads. All chromosomes assume a rod shape when in the metaphase plate. A pair of heterochromosomes was observed to be slower than the rest in assuming the rod shape and in getting into the plate. The marching of the synaptic mates toward their respective poles is asynchronous. Second division begins right after the chromosomes have reached the poles. Zwischenkörper observed at the end of the second division are regarded as formed by the granules seen in the polar regions during the first division.
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    Journal of Morphology 55 (1933), S. 15-28 
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    Notes: The first stage in the formation of the liver is two ventrolateral evaginations of the mid-gut at the time of hatching. From the undifferentiated cells branching from the liver duct the pancreas cells arise, but do not assume adult character until the carp is about 41 mm. long.The islet makes its first appearance in the region of the pancreatic duct at the 8-mm. stage and shows no transitional stages. In the mesenchyme itissue dorsal to the intestine the spleen arises, and is finally completely surrounded by the liver-pancreas.
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    Journal of Morphology 55 (1933), S. 185-191 
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    Notes: In this peculiar Orthopteron the chromosomes are unusual in these respects: the number is low for one of the Saltatoria; there is an x-y idiochromosome pair; all the tetrads are individually distinguishable; the chromosomes are small, relatively and actually, in the very large first spermatocyte. The structural peculiarities of the animal are reflected in those of its germ cells, but as yet no correlation has been established.
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    Journal of Morphology 55 (1933), S. 193-205 
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    Notes: Tritrichomonas foetus (Riedmüller) which occurs in the genital tract of domestic cows and which appears to be associated with pathological conditions, including sterility and abortion, has been found in American cows and its morphology studied.The spindle-shaped body is 10 to 25 μ in length and bears three anterior flagella and a posterior flagellum which constitutes the marginal filament of the nearly full-length undulating membrane and continues posteriorly as a trailing flagellum. There is an accessory filament in the undulating membrane. The axostyle is of the thick, hyaline type and contains endoaxostylar granules in the capitulum and bears a chromatic ring at the point of emergence from the body. There is a well-developed costa under the undulating membrane and a simple type of parabasal body.In its morphology this species more nearly resembles such intestinal forms as T. augusta and T. muris than it does Trichomonas vaginalis of man, since the latter has four anterior flagella, a short undulating membrane without an accessory filament, no trailing flagellum, a different type of axostyle, and a parabasal filament along with its larger parabasal body.
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    Journal of Morphology 55 (1933), S. 265-311 
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    Notes: X-rays produce fragmentations of the chromosome commonly in the region of fiber attachment.Fiberless fragments become attached to other chromosomes or those portions of them that retain fiber attachments. Thus, chromosomes homologous to parts of two other chromosomes are produced and at synapsis multiples are formed. Such multiples are chains or closed-circles depending upon whether a single or a reciprocal translocation respectively has occurred. Sometimes entire chromosomes unite to form a multiple. In general, the multiples divide so that the segregation of homologous elements is complete. However, sometimes the separation of homologous portions is impossible and, then, gametes which contain sectional-duplications, or sectional-deficiencies, or both, are produced. Any two or more chromosomes may be involved in multiple formation although the larger elements are more frequently implicated.Translocations may occur between homologues resulting in an unequal division of chromatin.The locus of fiber attachment (acromite) is an integral part of a chromosome and its loss to one homologue causes non-disjunction or other inequalities in the distribution of the chromatin.Supernumerary chromosomes are frequently present in the spermatocytes.Homologues unaccountably sometimes fail to synapse in the descendants of irradiated cells.There is a striking similarity between natural and induced chromosomal aberrations as well as a correlation between the distribution of radioactive minerals and naturally occurring aberrations.
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  • 65
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    Notes: S. scalaris (Orthoptera, Truxalinae) from Scotland and Siberia has a diploid complex of seventeen chromosomes (six V-multiples and eleven rods). Each element possesses a polar or proximal granule recognizable throughout all stages of prophase of the first spermatocyte and in all other stages when concentration is not so great as to mask it. In telophase of the first spermatogonial division the polar granules may fuse into a single body or into several irregular bodies (chromoplasts of Eisen and Janssens). By the end of the diatene stage the chromoplast is completely resolved into its component granules which are clearly recognizable as the proximal parts of the rods (ends) and of the multiples (mid-portions). The accessory chromosome is precocious in its behavior and differential in structure at all stages, but its peculiarities are most marked in metaphase of the first spermatocyte where it becomes a non-chromatic vesicle with peripheral granules and chromatic core. Each multiple arises from the permanent fusion of two rod elements. They differ from those in other members of the same sub-family in diakinesis (eight-strand or octad stage) in that proximal concentration extends almost throughout the multiple.
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  • 66
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    Notes: Rats in different stages of maturity were castrated in pairs-bilaterally and unilaterally-with respect to the effects upon the epipidymis. The epididymis was also studied during its developmental stages. A special study was made of the mitochondria and Golgi materials; and a comprehensive review of the literature is included.Bilateral castration was followed by a marked regression of functional activity on the part of the epithelial cells of the epididymis. Unilateral castration produced no similar change. The mitochondria-Golgi complex in the epithelial cells of the epididymis was reduced decidedly following bilateral castration; while unilateral castration had no visible effect upon these materials. The mitochondria-Golgi complex increased and decreased in amounts in keeping with the state of secretory activity of the epithelial cells.Golgi nets were found within the lumina of the tubules. Granules within the cells and the tubules were colored with osmic acid, Altmann's anilin acid-fuchsin, iron hematoxylin, or acid fuchsin-orange G. Osmic acid impregnation was removed from granules and nets and Altmann's anilin acid-fuchsin stain put in its place.It is believed that mitochondria and Golgi materials are very similar and furthermore that they are secretory products of the cells. It is also believed that the state of development of the mitochondria-Golgi complex is an indication of the functional state of the epithelial cells of the epididymis.
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    Journal of Morphology 55 (1934), S. 565-565 
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    Journal of Morphology 56 (1934), S. 1-19 
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    Notes: The origin and development of the posterior cardinals and associated veins in relation to the swim bladder, as well as their morphology, have been studied in Lepidosteus. The posterior cardinals develop, beginning in the 4-mm. stage, as sinuses in the mesenchyme dorsal to the gut and near the mesonephori. A pneumatic vein appears first in the 13-mm. stage. It collects from the posterior portion of the swim bladder and empties into the right posterior cardinal. In the younger stages the caudal vein empties directly into the posterior cardinals as is the case in the adult cyclostome, but by the 58-mm. stage it has joined veins dorsal to the mesonephori forming a renal portal system. An anal vein appears in the region of the anus and joins the caudal. Later, with the development of the renal portal system, the anal separates from the caudal to become the single posterior extension of the posterior cardinals. The posterior portion of the right cardinal contributes largely to the development of an abdominal portal vein extending from the posterior root of the right posterior cardinal to the liver. These relationships of the posterior cardinals differ from those found in other fishes, due perhaps to the function of the right cardinal and its pneumatic branch in collecting blood from the swim bladder.
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    Journal of Morphology 56 (1934), S. 101-123 
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    Topics: Biology , Medicine
    Notes: Chemical analyses of the lipoids in fresh and autolyzed pancreas of the cat have been correlated with the staining reactions of sections of this organ preserved by three cytological methods. Quantities of total fats and of phospholipins, the iodine numbers of total fats and of phospholipins, and the free fatty acid numbers were determined. None of the methods of fixation used reveals the total fat content of the tissue. The intensity of staining of material fixed by Helly's method and stained with acid fuchsin is dependent on the phospholipins of the tissue, but the exact nature of the relationship is not certain. The intensity of staining of material preserved by Champy's method and stained with acid fuchsin can be correlated with the iodine number of the phospholipins of the cells. The degree of blackness of sections preserved by the Kolatchev-Nassonov method can be correlated with the iodine number of the phospholipins of the cells. The free fatty acid content is probably also a significant factor. The methods demonstrate lipoids qualitatively rather than quantitatively. Only physiologically similar cells may justifiably be compared by the cytological methods studied.
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    Journal of Morphology 56 (1934), S. 157-179 
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    Notes: Two features of this study have furnished direct evidence for the material continuity and individuality of the chromosomes in the epithelial cells of the larvae of Ambystoma tigrinum (1) the tracing of the complete history of a specific chromosome, the nucleolus-containing chromosome, throughout the successive stages of mitosis and interkinesis, (2) the following of the exact parallelism in behavior (during mitosis) of the chromosomes in a given nuclear group with that in a single chromosome which has been isolated in the cytoplasm from the main chromosomal complex.Each of the two nucleoli is subterminally located in the short arm of one of two particular V-shaped chromosomes. The latter are probably homologues.78: In this subterminal chromosomal position the nucleolus exhibits in fixed and stained preparations an achromatic character in late prophase, metaphase, anaphase and early telophase, while it presents itself as a chromatic element in middle telophase, late telophase, interkinesis and early prophase.The nucleolus is not a simple homogeneous body, but rather a complex structure, the nature of which is revealed in the study of its evolution during the chromatic phase of its cycle in mitosis.
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    Journal of Morphology 56 (1934), S. 203-212 
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    Notes: The skull, mandible, and five pairs of long bones from the skeletons of 125 muskrats were weighed and measured. Each bone of the pairs of long bones was weighed and measured separately. Thirteen dimensions of the skull were determined.The long bones are slightly less variable in length than the skull dimensions. There is a rather wide range of variation in the thirteen dimensions of the skull, with the length and breadth of the skull less variable than the lengths of the long bones.The coefficients of correlation show that the weight of the skull is a good index to the weights of the long bones. The skull length has likewise high correlations with the lengths of the long bones and the longitudinal dimensions of the skull, with the exception of the palatine slits. The transverse diameters are not significantly correlated with the skull length.The long bones are asymmetrical in weight and length. They are longer more frequently on the left side and all except the tibia are heavier more frequently on the left side.
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    Journal of Morphology 56 (1934), S. 243-265 
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    Notes: The position of the inner ear and its relation to surrounding structures in the fetal head is ascertained. The growth and shape change of the cochlea is followed and measured. The change in size and appearance of the ductus cochlearis has been followed througout the various fetal stages. The growth and development of the scala vestibuli and scala tympani have been noted. The size and shape of the cells of the organs of Corti and the development and attachments of the tectorial membrane have been measured. The growth and developmental relationships of the tunnel of Corti have been followed. The growth and time of appearance of the organs with their relationship to hearing have been treated. The type of cell structure and the various structural changes throughout the development have been noted and correlated with the growth and size of the structure as a whole. The repidity of growth of all separate parts has been correlated and united to show the extent of development of the newborn rat inner ear.
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    Journal of Morphology 56 (1934), S. 361-369 
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    Notes: The diploid number of chromosomes of a species of Indian earwigs, Labidura riparia, is fourteen; six pairs of autosomes with X and Y idiochromosomes for the male; six pairs of autosomes with X and X for the female.The chromosome distribution is normal, and constant for all the individuals studied.X and Y are derived from a single chromatin nucleolus of the early growth period which assumes a clavate form later, and remains in the same form till the metaphase of the primary spermatocyte is reached.
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    Notes: During spermatogonial stages in Xiphophorus and Platypoecilus maculatus and Platypoecilus couchiana and in the hybrid, two distinct types of cells are observed, a large lightly staining primary spermatogonium and a smaller deeply staining secondary spermatogonium. Chromosomes of primary spermatogonia of Platypoecilus maculatus and Platypoecilus couchiana differ somewhat from those of Xiphophorus helleri and Xiphophorus jalapa, but are very similar to those of the hybrid at this stage.Chromosomes of Xiphophorus at this stage are long and thin, while those of Platypoecilus and of the hybrid are somewhat short and thick. Visible chromosome differences appear only during the primary spermatogonial stages.The haploid group of chromosomes, numbering twenty-four in the hybrid, so resembles that of Xiphophorus and of these two species of Platypoecilus in both number and morphological characteristics during the primary spermatocyte division as to be practically indistinguishable from either. Persistent lagging of one large chromosome as it comes upon the equatorial plate during the primary spermatocyte division is very noticeable. Precocious division of this chromosome and the advancing of its two daughter components to the poles of the spindle in advance of other chromosomes indicates that this chromosome may be a sex chromosome. The fact that two daughter components are identical morphologically and that each secondary spermatocyte receives one of them suggests that the male in Xiphophorus and in Platypoecilus is homogametic.
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    Journal of Morphology 56 (1934), S. 577-591 
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    Notes: The nuclear band of the cells of the salivary glands of Chironomus larvae regularly consists of four segments or chromosomes. Each of these may be recognized by its characteristic distribution of chromatin discs of various sizes. When nucleolar elements are present they have a definite location in relation to the chromation discs of a certain chromosome. The diploid number of chromosomes is eight; therefore, the four segments in the cells of the salivary glands represent four pairs of homologous chromosomes in somatic synapsis which here is not a simple approximation but an accurate pairing part by part of the homologous chromosomes.
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    Journal of Morphology 56 (1934), S. 593-601 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The rate of maturation and of development during the first 4 days has been followed in Melanoplus differentialis eggs (from mated females) collected (1) just before they were laid, or (2) immediately after oviposition had been completed and (1) either fixed at once, or (2) after incubation at 25°C. for definite periods.
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    Journal of Morphology 56 (1934), S. 603-619 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Maturation and early cleavage in unfertilized Melanoplus differentialis eggs have been followed with material secured immediately before as well as after oviposition, and (1) fixed at once, or (2) held in an incubator at 25°C. and, subsequently, fixed at selected intervals. Eggs ready to be laid were all found in the metaphase of the first maturation division. The second polar body is given off (at 25°C.) within 5 to 7 hours after laying. Meiosis appears to be unaffected by the absence of the sperm nucleus and proceeds at the same rate as in fertilized eggs. No morphological differences could be found between the process here and in eggs from mated females.During early cleavage, or later, the diploid number of chromosomes may be restored in some (or perhaps all) cells of the embryo.Development begins in the greater number of these unfertilized eggs but is successfully completed in only a very few.
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    Journal of Cellular and Comparative Physiology 2 (1933), S. 381-397 
    ISSN: 0095-9898
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Topics: Biology , Medicine
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    Journal of Cellular and Comparative Physiology 2 (1933), S. 457-466 
    ISSN: 0095-9898
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Topics: Biology , Medicine
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    Journal of Cellular and Comparative Physiology 3 (1933), S. 29-43 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Topics: Biology , Medicine
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 3 (1933), S. 169-202 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 3 (1933) 
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    Journal of Cellular and Comparative Physiology 2 (1933), S. 367-380 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 4 (1934) 
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    Journal of Cellular and Comparative Physiology 2 (1933), S. 467-478 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 4 (1934), S. 283-296 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 5 (1934), S. 229-247 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 5 (1934), S. 347-358 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 5 (1934), S. 399-413 
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    Journal of Cellular and Comparative Physiology 5 (1934), S. 151-169 
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    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
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    Journal of Cellular and Comparative Physiology 3 (1933), S. 313-340 
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    Journal of Cellular and Comparative Physiology 3 (1933), S. 355-383 
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    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
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