ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • phosphorus  (43)
  • Drosophila  (42)
  • stability  (40)
  • Springer  (125)
  • 1995-1999
  • 1990-1994  (125)
  • 1940-1944
  • 1925-1929
  • 1992  (125)
  • 1983
  • 1980
  • 1929
  • 1928
  • 1925
Collection
Years
  • 1995-1999
  • 1990-1994  (125)
  • 1940-1944
  • 1925-1929
  • 1980-1984  (72)
Year
  • 101
    Electronic Resource
    Electronic Resource
    Springer
    Human ecology 20 (1992), S. 145-167 
    ISSN: 1572-9915
    Keywords: agriculture ; development ; diversity ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Energy, Environment Protection, Nuclear Power Engineering , Ethnic Sciences
    Notes: Abstract This paper reconsiders two widely held hypotheses about the effects of the green revolution, that it led to biological simplification and instability. The hypothesis of biological simplification (genetic erosion) is tested with evidence from Andean agriculture, where farmers maintain a significant degree of crop diversity even as they adopt modern crop varieties. The hypothesis of increased instability is tested with evidence from Asia where wheat and rice yields show no general pattern of increased instability. Neither of these hypotheses is confirmed. The conventional wisdom about the green revolution should be reconsidered with emphasis on resilience and variation in modernizing farming systems.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 102
    Electronic Resource
    Electronic Resource
    Springer
    Hydrobiologia 233 (1992), S. 225-233 
    ISSN: 1573-5117
    Keywords: ditches ; fish stock ; dredging ; biomanipulation ; eutrophication ; phosphorus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In the polder ‘Wormer, Jisp and Nek’, which forms part of a grossly eutrophicated region in the province North Holland, the effects of dredging and biomanipulation were studied in ditches. Four areas, including 5.7 ha surface water in total, were dammed up and dredged. It was feasible to remove the loose top-layer of sediments with a high content of phosphorus by modifications of the dredging machine. In two areas the fish stock was managed. The measures resulted in an improvement of the water quality: an increase of the transparency and a decrease of suspended solids, phosphorus, nitrogen and algae. The chlorophyll-a concentration decreased nearly to 100 µg l−1 (summer average). The relative densities of diatoms, green algae and cyanobacteria did not change. The zooplankton community was dominated by small rotifers and crustaceans both before and after restoration measures. Cladocerans were scarcely present. In the second year after the measures, submerged macrophytes developed.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 103
    ISSN: 1573-5117
    Keywords: nitrogen ; phosphorus ; underwater light ; primary production ; secondary production
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The study provides a 2.5 year record of Rhenosterkop Dam (KwaNdebele, South Africa) plankton population dynamics and production in relation to physical and chemical changes which occurred during the trophic depression and stabilization phases of the reservoir. The mean volume of the reservoir was 4% of full storage capacity. Water temperatures ranged from 14 °C to 27 °C. Due to inorganic suspensoids, the euphotic zone averaged 2.6 m. An anaerobic zone developed each summer. The nitrogen, soluble reactive phosphorus (SRP) and silica concentrations did not displaya seasonal pattern, but the latter two nutrients declined over the study. The dominant phytoplankton group was the cryptophytes while the zooplankton population was dominated by crustaceans. Chlorophyll a concentrations ranged from 1.1 to 27 mg m−3 and were positively correlated to silica and SRP concentrations and inversely with NH4-N concentrations. Primary production ranged from 22.6 to 375 mgC m−2 h−1; changes in Amax were positively correlated to silica and SRP concentrations. Total zooplankton dry weight biomass varied from 〈0.5 to 〉4 mg l−1. Annual zooplankton (secondary) production was 8 to ∼ 15 gC m−3 a−1; both primary and secondary production were greatest in the first 12 months of study and remained at low levels for the remainder, similar to the trends for silica and SRP. The data indicate that the reservoir shifted from eutrophic to mesotrophic during the study, typical of events in new reservoirs, and that changes in the plankton populations were largely the result of changing nutrient concentrations.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 104
    ISSN: 1573-5117
    Keywords: disturbance ; recovery ; fire ; streams ; stability ; macroinvertebrates ; watershed
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Macroinvertebrate communities of five headwater streams in catchments disturbed by wildfire were compared with five similar streams with no catchment disturbance. Over the five years of observation, communities in disturbed streams were more similar to one another than they were to reference streams. Communities in disturbed streams exhibited more year-to-year variation than reference streams, although some indication of decreasing variation was evident through time, and species richness was greater in reference streams than disturbed streams. No increasing trend in richness over time was observed in disturbed streams. Stability of the relative abundance structure and persistence of dominant taxa through time may be characteristic of temperate streams over moderate time intervals. Local effects of catchment-wide disturbance have persistent effects that alter these trends.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 105
    ISSN: 1573-5036
    Keywords: bulk density ; epoxy resin impregnation ; image analysis ; macroporosity ; nitrogen ; stability ; strength ; structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Soil aggregate stability, organic matter content, pH, bulk density, strength, and macropore attributes were assessed in order to evaluate the influence of grass root growth in a field sward. The amount of grass grown was varied by varying the quantity of applied nitrogen fertilizer: following one year with a uniform application rate, nitrogen fertilizer was applied over the subsequent three years to a compact soil at zero (N0), moderate (N1) and high (N2) rates. Differences in herbage production were evident in the three years of the contrasting nitrogen treatments. An index of soil aggregate stability increased in response to the increased grass growth promoted by heavier applications of nitrogen, but both bulk density and vane shear strength were unchanged. Binary images of the soil solid and pore space showed that for each treatment the largest volume of macropores occurred close to the surface, particularly in N0 where there was more pore space than in either N1 or N2. Analysis of the pore structure attributes of the binary images revealed further differences between treatments, in particular, at 40–80 mm depth, the soil in treatment N0 had fewer and smaller pores, and greater distance between pores, than the soil in the N1 and N2 treatments. The larger macropore volume in N1 and N2 constituted a major portion of the air-filled porosity when the soil was relatively wet. It was concluded that the root growth in the intensively cropped grassland was conducive to maintenance of a relatively stable and porous soil structure. An attendant increase in soil acidity close to the soil surface was a disadvantage of the larger nitrogen inputs.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 106
    ISSN: 1573-5036
    Keywords: nitrogen ; phosphorus ; root: shoot ratios ; secondary succession ; semiarid ; shrubland ; tissue nitrogen ; tissue phosphorus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Above- and below-ground biomass production, nitrogen (N) and phosphorus (P) tissue concentrations, and root: shoot ratios were examined for five species that are characteristic of a semiarid successional sequence under controlled greenhouse conditions. In two simultaneous experiments, seedlings of one forb, two grass, and two shrub species important in a sagebrush successional sere, were subjected to seven levels of N and P. Results of the experiments suggest distinct differences in nutrient response patterns between early and late seral species. Early seral species produced more biomass but had lower tissue nutrient concentrations than late seral species. As N and P availabilities decreased, late seral species displayed characteristics indicative of increasing competitive advantage over those of early seral species. Root: shoot ratios of the five species primarily reflected patterns related to lifeform, but with some early and late seral characteristics. Results from this study 1) confirm that nutrient use pattern, nutrient availability, and seral position relationships characteristic of mesic ecosystems hold equally true for semiarid systems, and 2) suggest that nutrients are important organizing factors in semiarid ecosystems.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 107
    ISSN: 1573-5060
    Keywords: population improvement ; maize ; Zea mays ; honeycumb selection ; adaptability ; stability ; yield
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary This study was undertaken to investigate the implications of genotype x soil texture interaction on response to selection in maize. Mass honeycomb selection for yield was applied for 11 cycles from the F2 of the single cross maize hybrid F68×NE2 in a field B with silty-clay-loam soil texture. Response to selection compared to the original single cross hybrid was estimated both in absence of competition and under solid stand in the selection field B and in a nearby field A differing in soil texture (clay-loam). A strong crossover type of interaction occurred both under solid stand and in the absence of competition in the two tests the improved population outyielded the hybrid in field B in the two densities, but lagged behing the hybrid in field A. The results suggest that interaction between genotype and soil texture might affect efficiency of selection detrimentally unless provision is taken for parallel selection early in the crop improvement program in fields differing in soil texture.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 108
    ISSN: 1573-5060
    Keywords: chickling ; Lathyrus ; G×E interactions ; adaptation ; stability ; heritability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Sixteen promising lines (selections) of Lathyrus spp. (chicklings), comprising 11 L. sativus, four L. ochrus, and one L. cicera, were evaluated under rainfed conditions in Syria. Two locations in each of four years were treated as separate environments, to give eight environments altogether. Genotype x environment (G×E) interactions were analysed using linear regression. There was considerable variation in herbage and seed yields within both lines and environments. Genotype x environment interactions were present for both herbage and seed yields; a little over half was accounted for by the linear regression. The non-linear component was also significant, although it was smaller than that of the linear component. The most stable herbage and seed yields were obtained from L. sativus. Two selections, 347 and 311, origmating from Syria and Turkey respectively, combined both high herbage and seed yields with wide adaptation and stability, and could be considered the most widely adapted lines. Other lines were identified as suitable for favourable and unfavourable environments; in particular, all four lines of L. ochrus have great potential in frost-free climates. The importance of genotype x environment interactions in future breeding strategies is discussed.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 109
    ISSN: 1573-515X
    Keywords: algae ; nitrogen ; nutrient ; phosphorus ; regeneration ; zooplankton
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Geosciences
    Notes: Abstract Most ecosystem models consolidate members of food-webs, e.g. species, into a small number of functional components. Each of these is then described by a single state variable such as biomass. When a multivariate approach incorporating multiple substances within components is substituted for this univariate one, a ‘stoichiometric’ model is formed. Here we show that the Nitrogen:Phosphorus ratio within zooplankton herbivores varies substantially intraspecifically but not intraspecifically. By using stoichiometric theory and recent measurements of the N:P ratio within different zooplankton taxa, we calculate large differences in ratios of nutrients recycled by different zooplankton species. Finally, we demonstrate that N:P stoichiometry can successfully account for shifts in N- and P-limitation previously observed in whole-lake experiments. Species stoichiometry merges food-web dynamics with biogeochemical cycles to yield new insights.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 110
    Electronic Resource
    Electronic Resource
    Springer
    Journal of comparative physiology 162 (1992), S. 278-283 
    ISSN: 1432-136X
    Keywords: Biological oscillator ; Deuterium ; Drosophila ; Heart rate ; Temperature
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A non-intrusive optical technique has been developed to monitor heartbeat in late third-instar Drosophila larvae. Heartbeat in this insect is an oscillation that is not temperature compensated. Deuterium oxide lengthens the period of a number of high and low frequency oscillators and clocks in a variety of organisms. To determine whether deuterium affects heart rate, flies were raised on proteated and deuterated media and their heartbeat was monitored at four temperatures ranging from 18 to 33°C. The rate of heartbeat increased linearly with increasing temperature, and decreased with increasing concentrations of deuterium. There was a significant interaction between temperature and deuterium: the higher the concentration of deuterium oxide the less temperature-sensitive was the heart rate. Raising temperatures also increased the amount of “noise” in the rhythm: signal-to-noise ratio, which characterizes the amount of power in a rhythmic signal, decreased with increasing temperatures. Deuterium oxide had no effect on signal-to-noise ratio.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 111
    Electronic Resource
    Electronic Resource
    Springer
    Journal of comparative physiology 162 (1992), S. 203-208 
    ISSN: 1432-136X
    Keywords: Triacylglycerols ; Glycogen ; Reproductive diapause ; Overwintering ; Drosophila
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Temperate species of the Drosophila melanogaster group enter reproductive diapause for overwintering in response to short daylength. During the prediapause period they accumulate triacylglycerols, but not glycogen, as energy resources. The capacity for storing triacylglycerols differs between species, and appears to be closely correlated with diapause and cold-hardiness; cool-temperate species, such as those of the auraria species complex, which enter a deep diapause and are highly cold-hardy, accumulate larger quantities of triacylglycerols than warm-temperate species, such as D. rufa and D. lutescens, which enter a weak diapause and are less cold-hardy. Among the cool-temperate spcies, D. subauraria occurs at a higher latitude and has the greatest capacity for accumulating triacylglycerols. A subtropical species, D. takahashii, which has no diapause in nature and is not cold-hardy, is unable to store the same quantities of triacylglycerols as temperate species.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 112
    Electronic Resource
    Electronic Resource
    Springer
    Wetlands ecology and management 1 (1992), S. 211-222 
    ISSN: 1572-9834
    Keywords: freshwater marsh ; freshwater wetland ; Great Lakes ; hydrology ; phosphorus ; water quality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A coastal wetland along Lake Erie (Ohio, U.S.A.) was studied to determine hydrologic and phosphorus budgets and spatial and temporal variation of phosphorus and related chemical parameters. The wetland was influenced by changing Lake Erie water levels, seiches, shifting shoreline sediments, and watershed inflow during a year of severe drought. The water budget for a 7-month period (March – September, 1988) had average inflow of 15 200 m3 day−1 from the watershed and 3.5 m3 day−1 from Lake Erie. The wetland increased in volume by 700 m3 day−1 despite a drought that resulted in 80% more evapotranspiration than rainfall as a barrier beach isolated the wetland from Lake Erie for 77% of the study period. Conductivity decreased by 34% as water flowed through the wetland and turbidity and total suspended solids were variable and statistically similar at inflow and outflow. Average total phosphorus concentrations in the inflow and outflow were also similar (247 and 248 µg P l−1 respectively) although total soluble phosphorus and soluble reactive phosphorus decreased significantly (α=0.05) from inflow to outflow (averages 94 to 45 µg P l−1 and 7.5 to 4.0 µg P l−1 respectively). Nutrient budgets from field data estimate a retention of 36% of the phosphorus, presumably in the sediments (0.8 mg P m−2 day−1). A general nutrient retention model, an estimated deposition rate from a sediment core and a simulation model predicted higher mass retention of phosphorus but similar percentage retention. Sommaire Un marecage qui côtoie le lac Erie (USA) a servi de site expérimental pour en déterminer les budgets d'eau et de phosphore, de même que pour la variation spatiale et temporelle du phosphore et d'autres facteurs chimiques. Le marécage a été influencé par: niveaux d'eau qui changeaient; seiches; sédiments mouvants du littoral; et afflux de la ligne de partage des eaux dans une année de grande sécheresse. Le budget d'eau dans une période de 7 mois (mars–septembre 1988) montre un afflux de 15 200 m3 jour−1 de la ligne de partage, et 3.5 m3 jour−1 du lac Erie. Le volume du marécage a augmenté par 700 m3 jour−1 malgré une sécheresse qui a produit plus d'évapotranspiration (80%) que de pluie pendant qu'une plage-obstacle a isolé le marecage du lac Erie pendant 77% de la période d'observation. La conductivité a diminué par 34% pendant que l'eau coulait, et la turbidité et les TSS ont varié, tout en démontrant des statistiques similaires à l'afflux et au déversement. Les moyennes pour les concentrations du total du phosphore à l'afflux et au déversement ont été similaires (247 and 248 µg P l−1), quoique le TSP et le SRP ont diminué (α=0.05) de l'afflux au déversement (donant des moyennes de 94 à 45 µg P l−1 et de 7.5 à 4.0 µg P l'−1). Les budgets de substances nutritives pour les données suggèrent une reténtion de 36% du phosphore, évidemment dans les sédiments (0.8 mg P m−2 jour−1). Un modèle pour la rétention des nutrients, un taux de déposition, estimé par un noyau de sédiments, et une simulation avaient prédit un plus grand taux de rétention de phosphore, mais un pourcentage similaire pour la rétention.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 113
    Electronic Resource
    Electronic Resource
    Springer
    Wetlands ecology and management 1 (1992), S. 239-247 
    ISSN: 1572-9834
    Keywords: biomass ; carbohydrates ; nitrogen ; phosphorus ; Phragmites australis ; potassium ; reed ; rhizome ; translocation ; wetland
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Seasonal changes in rhizome concentrations of total nonstructural carbohydrates (TNC), water soluble carbohydrates (WSC), and mineral nutrients (N, P and K) were monitored in two Phragmites australis stands in southern Sweden. Rhizome biomass, rhizome length per unit ground area, and specific weight (weight/ length ratio) of the rhizomes were monitored in one of the stands. Rhizome biomass decreased during spring, increased during summer and decreased during winter. However, changes in spring and summer were small (〈 500 g DW m-2) compared to the mean rhizome biomass (approximately 3000 g DW m−2). Winter losses were larger, approximately 1000 g DW m-2, and to a substantial extent involved structural biomass, indicating rhizome mortality. Seasonal changes in rhizome length per unit ground area revealed a rhizome mortality of about 30% during the winter period, and also indicated that an intensive period of formation of new rhizomes occurred in June. Rhizome concentrations of TNC and WSC decreased during the spring, when carbohydrates were translocated to support shoot growth. However, rhizome standing stock of TNC remained large (〉 1000 g m−2). Concentrations and standing stocks of mineral nutrients decreased during spring/ early summer and increased during summer/ fall. Only N, however, showed a pattern consistent with a spring depletion caused by translocation to shoots. This pattern indicates sufficient root uptake of P and K to support spring growth, and supports other evidence that N is generally the limiting mineral nutrient for Phragmites. The biomass data, as well as increased rhizome specific weight and TNC concentrations, clearly suggests that “reloading” of rhizomes with energy reserves starts in June, not towards the end of the growing season as has been suggested previously. This resource allocation strategy of Phragmites has consequences for vegetation management. Our data indicate that carbohydrate reserves are much larger than needed to support spring growth. We propose that large stores are needed to ensure establishment of spring shoots when deep water or stochastic environmental events, such as high rhizome mortality in winter or loss of spring shoots due to late season frost, increase the demand for reserves.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 114
    Electronic Resource
    Electronic Resource
    Springer
    Plant foods for human nutrition 42 (1992), S. 313-318 
    ISSN: 1573-9104
    Keywords: Iron availability ; phosphorus ; soil iron level ; ascorbic acid ; oxalic acid ; spinach
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract In vitro availability of iron along with ascorbic acid, oxalic acid and phosphorus content of two varieties of spinach (Pusa Jyoti and Allgreen) cultivated in soil with different levels of added iron was determined. Addition of graded levels of iron to soil markedly increased the total iron and phosphorus contents and significantly decreased the bio-availability of iron, ascorbic acid and oxalic acid contents of spinach. Ascorbic acid and oxalic acid contents markedly exerted a positive influence while phosphorus exerted a negative influence on the bio-availability of iron.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 115
    Electronic Resource
    Electronic Resource
    Springer
    Pharmaceutical research 9 (1992), S. 1521-1523 
    ISSN: 1573-904X
    Keywords: salmon calcitonin ; stability ; kinetics ; peptide ; degradation ; pH–rate profile ; HPLC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 116
    Electronic Resource
    Electronic Resource
    Springer
    Pharmaceutical research 9 (1992), S. 406-409 
    ISSN: 1573-904X
    Keywords: centrifugation ; emulsification ; perfluorocarbon ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The effect of preparation temperature on the emulsification efficiency of perfluoro-3-butyltetrahydrofuran (FC-75) was investigated. Polyoxyethylene (POE) oleyl ether surfactants were used as the emulsifier(s) in a range of HLB values of 7.5 to 9.5. The emulsions were prepared by paddle mixing as a method of low-shear emulsification. After centrifugation of the resulting O/W emulsions, the volume of FC-75 which separated was utilized as a measure of the emulsification efficiency. In general, emulsions prepared at temperatures where the surfactant was in a lamellar-to-isotropic surfactant solution transition, Lα→ L3, displayed a better emulsification efficiency than those prepared with other surfactant phases.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 117
    ISSN: 1573-904X
    Keywords: monoclonal antibody ; lyophilization ; freeze-drying ; stability ; formulation ; cyclodextrin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The influence of lyophilization on the stability of a monoclonal antibody (MN12) was investigated. MN12 was freeze-dried in different formulations [without lyoprotectant or in the presence of sucrose, dextran, or hydroxypropyl-β-cyclodextrin (HPβCD)] and under varying conditions (with or without secondary drying). Subsequently, the monoclonal antibody was stored for 18 or 32 days at various temperatures (4, 37, or 56°C). For comparison, solutions of MN12 were stored under the same conditions. Regardless of the lyoprotectant used, precipitation and a concomitant reduction of the antigen-binding capacity by about 10% were observed upon recon-stitution of lyophilized MN12. HPβCD proved to be the most effective stabilizer to prevent degradation of lyophilized MN12 during storage. Compared with MN12 solutions, HPβCD-containing lyophilized MN12 cakes were more resistant to heat-induced charge alterations and loss of antigen-binding capacity.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 118
    ISSN: 1573-904X
    Keywords: glycosylation ; mass Spectrometry ; monoclonal antibody ; protein characterization ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 119
    ISSN: 1573-904X
    Keywords: capillary gas chromatography ; analysis ; stability ; urea derivative ; capsules ; mass spectrometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A method for the analysis of hydroxyurea (HU) in solutions, powder, or capsules by use of capillary gas chromatography with N–P thermionic specific detection is described. Upon injection of an HU solution in a methanol and acetone mixture, the drug formed pyridine which was well separated from the internal standard (thiotepa) on a 30-m fused-silica, SE-30 capillary column with temperature programming. The peak height ratio versus concentration standard curves were linear with correlation coefficient ranging between 0.9942 and 0.9993. The coefficients of variation at 5, 25, and 50 µg/L were 7.2, 5.7, and 5.5%, respectively. Hydroxyurea was extracted from powder or capsule formulations with a mixture of methanol and acetone (50:50, v:v), and the percentage found of the label claim for 10 capsules ranged between 96.7 and 104.9 (mean = 100.1; CV = 2.7%). Further, this assay was used to examine the stability of hydroxyurea in aqueous solutions at 4, 23, and 45°C, and the apparent first-order rate constants observed at these temperatures were 0.06407, 0.08113, and 0.1293 day-1, respectively; the activation energy was 3011 cal · K-1 mol-1.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 120
    Electronic Resource
    Electronic Resource
    Springer
    Pharmaceutical research 9 (1992), S. 312-315 
    ISSN: 1573-904X
    Keywords: controlled drug delivery system ; chronotherapeu-tics ; electrically modulated ; electrophoresis ; degradation of propranolol hydrochloride ; stability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A number of factors affecting the stability of propranolol HC1 during electrophoretic control were investigated. It was found that significant degradation of propranolol HC1 and hydrolysis of water occurred when a current of 15 mA was used with platinized electrodes. This degradation was thought to be due to decomposition of propranolol HC1 at the electrodes. Degradation could be significantly reduced by using uncoated platinum electrodes and currents in the range of 0 to 2.5 mA, while still allowing control of drug delivery rates. Electrode reaction processes were found at high ionic strengths and high drug concentrations but were not thought to be associated with drug decomposition.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 121
    Electronic Resource
    Electronic Resource
    Springer
    Pharmaceutical research 9 (1992), S. 939-944 
    ISSN: 1573-904X
    Keywords: calorimetry ; microcalorimetry ; stability ; kinetics, solid state ; degradation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A new technique has been developed to calculate rapidly the solid-state room-temperature degradation rate of drugs and drug candidates. The technique utilizes measurements of the initial rate of heat output at several elevated temperatures by isothermal calorimetry and the degradation rate of the compound determined at a single elevated temperature by chromatography. The activation energies and degradation rates at 25°C calculated by conventional methods and by isothermal calorimetry are compared and discussed. The compounds studied were phenytoin, triamterene, digoxin, tetracycline, theophylline, diltiazem, and several proprietary ICI compounds.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 122
    Electronic Resource
    Electronic Resource
    Springer
    Journal of optimization theory and applications 73 (1992), S. 27-45 
    ISSN: 1573-2878
    Keywords: Sensitivity ; stability ; nonlinear programming ; calmness
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract We consider a smooth nonlinear program subject to perturbations in the right-hand side of the constraints. We do not assume that the unique solution of the original problem satisfies any qualification hypothesis. We suppose instead that the direction of perturbation satisfies the hypothesis of Gollan. We study the variation of the cost and, with the help of some second-order sufficiency conditions, obtain some conditions satisfied by the first term of the expansion of the solution. These conditions may vary depending on the existence of a Lagrange multiplier for the original problem.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 123
    Electronic Resource
    Electronic Resource
    Springer
    Journal of chemical ecology 18 (1992), S. 2095-2105 
    ISSN: 1573-1561
    Keywords: Allelopathy ; Schizachyrium scoparium ; Ceratiola ericoides ; hydrocinnamic acid ; nitrogen ; phosphorus ; potassium ; fire ; sand pine scrub ; sandhill
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Bare zones around shrubs in the Florida scrub indicate the possibility of allelopathy by shrubs controlling the distribution of grasses invading from adjacent sandhills. The allelochemical, hydrocinnamic acid, has been identified as a breakdown product of ceratiolin, which is released from the shrubCeratiola ericoides. Here, hydrocinnamic acid (HCA) was shown to have a strongly inhibitory effect on shoot and root biomass of the grassSchizachyrium scoparium in greenhouse bioassays lasting 4.5 months. Linear increases in the concentration of HCA from 0 to 200 ppm, applied biweekly, resulted in exponential decreases in root and shoot biomass at harvest. Plants grown at 200 ppm HCA had root and shoot biomasses 13% and 17% of controls, respectively. Concurrent investigation of reduced nutrient levels indicated greater inhibition by HCA in a reduced nitrogen (N) treatment and in a reduced potassium (K) treatment relative to HCA inhibition in the full nutrient treatment. The negative slopes of the regressions of log of biomass on HCA concentration were steepest in the reduced N and reduced K treatments. Root and shoot biomasses in reduced N treatments were 20–43% and 24–34% less than the respective biomasses in the full nutrient treatment. Comparable reductions in the reduced K treatment were as much as 19% and 10% for root and shoot biomasses, respectively. The effects of HCA in a reduced phosphorus (P) treatment and in a reduced P and K treatment were not significantly different from the effects of HCA in the full nutrient treatment. Extraction of the soils at harvest indicated no buildup of HCA at the end of the experiment. The sensitivity ofSchizachyrium scoparium to HCA in general and increased sensitivity under low N and low K solutions may be important in the Florida scrub community where levels of N and K are known to be low.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 124
    Electronic Resource
    Electronic Resource
    Springer
    Nonlinear dynamics 3 (1992), S. 199-223 
    ISSN: 1573-269X
    Keywords: Twin-lift helicopter ; nonlinear model ; stability ; feedback linearization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The stability and control characteristics of two twin-lift helicopter configurations are analyzed in this paper. In order to address the issue of configuration selection from a handling qualities viewpoint, their open-and closed-loop characteristics are compared. The two twin-lift configurations considered are the twin-lift with spreader bar and twin-lift without spreader bar. The nonlinear models describing the dynamics of these two configurations in the lateral/vertical plane are derived. The open-loop characteristics of the two systems are compared by linearizing the nonlinear models about a symmetric hovering equilibrium condition. The closed-loop characteristics of the two systems are compared using nonlinear controllers based on feedback linearization schemes. The performance of the resulting closed-loop systems in carrying out a typical twin-lift mission is evaluated through nonlinear simulation. Also, the effects of helicopter performance degradation and measurement errors on the overall system performance are discussed. [B] Matrix multiplying the control vector in the nonlinear model [B1] Matrix multiplying the control vector in the linear model [C] Matrix defining vector of variables to be controlled [C1] Damping matrix CijElement of the damping matrix e Parameter used in the linear model = M 1 h 1/I 1=M 2 h 2/I 2,/ft {f} Vector independent of controls in the nonlinear model g Acceleration due to gravity, ft/sec2 h1, h2Distance of tether attachment point to the center of gravity for helicopters 1 and 2, ft h Parameter used in the linear model, =h 1=h 2, ft h′ Distance between rotor hub and the helicopter center of gravity, ft h h/l′ H Distance of the load from the spreader bar c.g., ft H1, H2Length of tethers 1 and 2, ft IRMass moment of inertia of spreader bar, slug-ft2 I1, I2Roll moments of inertia of helicopters 1 and 2, slug-ft2 k′ Non-dimensional hub control moment coefficient KDDerivative gains KIIntegral gains KPProportional gains [Ki] Stiffness matrix KijElement of the stiffness matrix l′ Parameter used in the linear model, =H 1=H 2, ft L Spreader bar length, ft
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 125
    Electronic Resource
    Electronic Resource
    Springer
    Flow, turbulence and combustion 49 (1992), S. 307-334 
    ISSN: 1573-1987
    Keywords: stability ; linear-stability analysis ; multi-layered flow ; Orr-Sommerfeld equations ; interfacial conditions ; generalized eigenvalue problem ; air-water flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The linear stability of the Poiseuille flow of multi-layered different fluids, described mathematically by a system of Orr-Somerfeld differential equations, is investigated. A spectral method is used to rewrite this system into a generalized eigenvalue problem, which can be solved with the QZ-algorithm. Special attention is paid to the tractibility of the interfacial conditions of the stability problem. Since we will limit ourselves to a linear stability analysis, the analytical treatment of the interfacial conditions is simplified. Some results related to simple flow configurations are presented. The origin of certain regions of interfacial instability is explained by simple analytical reasoning.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...