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  • Political Science  (1,618)
  • bic Book Industry Communication::M Medicine  (1,212)
  • Bolivia
  • M14
  • ddc:300
  • 2020-2024  (2,952)
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, recent advancements in the field of pediatric tumors are discussed, and novel prognostic markers are critically appraised. Greater understanding of the heterogeneity of pediatric cancers will ultimately lead to new therapeutic strategies with the potential to provide new prospects for precision medicine in pediatric oncology.
    Keywords: undernutrition ; obesity ; nutritional status ; childhood cancer ; overall survival ; event-free survival ; relapse ; treatment-related toxicity ; review ; sarcoma botryoides ; fertility-sparing surgery ; embryonal rhabdomyosarcoma ; genital tract ; prognosis ; treatment ; local debulking ; neoadjuvant chemotherapy ; radiation ; ovarian cancer ; adolescents ; diagnosis ; therapy ; guidelines ; children ; papillary thyroid cancer ; proto-oncogene B-raf gene (BRAF) ; craniopharyngioma ; recurrence ; risk factors ; youth ; acute lymphoblastic leukemia (ALL) ; child ; genetics ; CDKN2A/2B deletions ; fluorescent in situ hybridization (FISH) ; multiple-ligation probe amplification (MLPA) ; copy-number alterations (CNAs) ; risk stratification ; minimal residual disease (MRD) ; cardiotoxicity ; chemotherapeutics agents ; biomarkers ; omics technology ; medulloblastoma ; tumor ; histologic ; pediatrics ; micro-RNAs ; non-coding RNAs ; molecular subgroup ; stratification ; acute lymphoblastic leukemia ; proteomics ; oncology ; chemotherapy ; cardiac function tests ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 2
    Publication Date: 2024-02-05
    Description: In the southern border area, where Ecuador is located with neighboring Peru. There are two important cantons for its commercial passage, the canton Macará in the province of Loja, and the canton Huaquillas in the province of El Oro. Through the Coordination 7 of the Ministry of Public Health, thanks to the ProSalud Frontera Sur Project, the database of the Automated Daily Registry of Consultations and Outpatient Care was managed, which allowed us to clarify the problems at the public health level in these cantons. It can be observed throughout the text that women present a greater number of diseases compared to men, with the latter remaining stable over the three years for both Ecuadorians and foreigners.
    Description: Published
    Description: En la zona fronteriza sur, donde se localiza el Ecuador con el vecino país Perú. Se encuentran dos cantones importantes por su paso comercial, el cantón Macará de la provincia de Loja, y el cantón Huaquillas de la provincia de El Oro. En donde, por medio de la Coordinación 7 del Ministerio de Salud Pública se gestionó gracias al Proyecto ProSalud Frontera Sur, la base de datos Registro Diario Automatizado de Consultas y Atenciones Ambulatorias, que nos permitió clarificar la problemática a nivel de salud pública en estos cantones. Se puede observar a lo largo del texto que las mujeres presentan mayores cantidades de enfermedades frente a los hombres manteniéndose estables estos en los tres años y tanto para ecuatorianos como para extranjeros
    Keywords: bic Book Industry Communication::M Medicine
    Language: Spanish
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  • 3
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-04-08
    Description: Das Verhältnis von klassischen und modernen Theorien der Macht wird gemeinhin kontradiktorisch gedacht: entweder aus dem Glauben, beide Theorien würden sich systematisch ausschließen, oder basierend auf der Annahme, die modernen Machttheorien à la Michel Foucault hätten die klassischen à la Thomas Hobbes abgelöst. Das Phänomen der Macht aus einem wechselseitigen Verhältnis beider Ansätze zueinander zu begreifen, ist bisher ein Desiderat in der Forschung. Der Band wirft einen neuen Blick auf die Macht, indem er Beiträge zur Vermittlung beider Ansätze versammelt. Nicht nur wissenschaftliche, sondern auch künstlerische Beiträge machen das Phänomen aus einer ganzheitlicheren Perspektive heraus zugänglich.
    Keywords: Macht ; Herrschaft ; Theorie ; Performative Philosophie ; Performance ; Politik ; Politische Philosophie ; Politische Theorie ; Politische Soziologie ; Politikwissenschaft ; Philosophie ; Power ; Power Relations ; Theory ; Performative Philosophy ; Politics ; Political Philosophy ; Political Theory ; Political Sociology ; Political Science ; Philosophy ; bic Book Industry Communication::H Humanities::HP Philosophy::HPS Social & political philosophy ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPA Political science & theory ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTS Social and political philosophy ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology
    Language: German
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Metronomic chemotherapy is now, finally, in clinical use. After 20 years of preclinical development and clinical trials, the emerging data will be of paramount importance in allowing us to assess the impact of metronomic chemotherapy on different tumor types. Indeed, it is likely that the next decade will see a major reassessment of the possible applications of metronomic chemotherapy, both alone and in combination with new therapeutic approaches such as immunotherapies, for the management of cancer. Moreover, the results of clinical trials will likely profoundly affect the direction of the laboratory efforts that are going on in parallel and aiming to improve the personalization of this therapeutic strategy. This Special Issue is our attempt to cover the past and present clinical results that have brought us to this pivotal moment and will form the basis of future clinical developments. Scientists and clinicians caring for cancer patients are well aware of the challenges in dealing with this particular therapeutic approach; one such challenge is obtaining improvements in patient survival without significant toxicity. This edition includes clinical research on chemotherapy and ongoing controversies related to metronomic chemotherapy.
    Keywords: metronomic ; oral cancer ; oral squamous cell carcinoma ; metronomic chemotherapy ; metastatic castration-resistant prostate cancer ; cyclophosphamide ; side effects ; pediatric tumors ; etoposide ; valproic acid ; prostate cancer ; CRPC ; castration ; capecitabine ; paclitaxel ; immunomodulation ; angiogenesis ; microbiome ; breast cancer ; safety ; preclinical studies ; clinical studies ; pharmacokinetic studies ; biomarkers ; chemo-free ; DLBCL ; diffuse-large-b-cell-lymphoma ; elderly ; frail ; comprehensive geriatric assessment ; chemo-endocrine therapy ; FulVEC ; pediatric oncology ; brain tumors ; pharmacology ; medulloblastoma ; ATRT ; immunotherapy ; lymphoma ; vinorelbine ; checkpoint inhibitors ; bic Book Industry Communication::M Medicine
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This collection of articles provides insight into the mental health and nursing care of individuals who are confronting a life-threatening illness. As individuals face a cancer diagnosis, there will be many challenges and changes in their lives. Emotional distress can emerge to greater and lesser degrees. Frequently, these individuals will require additional assistance to cope with the emotional distress they experience. Nurses have an important role in assessing this emotional distress and providing relevant interventions.
    Keywords: Latinx ; family ; meaning ; communication ; coping with advanced cancer ; delirium ; liaison nurse ; misrecognition of delirium ; coordination ; breast cancer ; psychological distress ; quality of life ; women’s health ; qualitative study ; cancer care ; older adults ; mental health ; feeling safe ; home-dwelling ; patients with terminal cancer ; caregivers ; competency in anticipatory grief counseling ; emotional care ; person-centered care ; qualitative research ; anxiety ; depression ; family involvement ; hepatocellular carcinoma ; palliative care ; cancer ; decision-making ; nurse ; caregiving self-efficacy ; family caregiver ; oral cancer ; oncology ; nursing ; clinical nurse specialists ; cancer patients ; expanding nurses’ authority ; professionalization ; policy ; education ; bic Book Industry Communication::M Medicine
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Obstructive sleep apnea is a highly prevalent disorder with strong associations with cardiovascular, cerebrovascular, metabolic, and cognitive consequences, including drowsy driving. Positive Airway Pressure treatment is the first-line therapy for adults with obstructive sleep apnea who are symptomatic. However, many individuals with comorbidities do not report symptoms that are associated with the disorder, and adherence to treatment is poor, especially in individuals with cardiovascular diseases. This reprint contains reviews and original articles that aim to update the current perspectives on the treatment modalities of obstructive sleep apnea to highlight multidisciplinary approaches, personalized treatment strategies, and the identification of the predictors of a patient’s response to treatment, both in the general population and in clinical cohorts.
    Keywords: obstructive sleep apnea (OSA) ; continuous positive airway pressure (CPAP) ; mandibular advancement devices ; upper airway surgery ; drowsy driving ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
    Language: English
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  • 7
    Publication Date: 2024-01-08
    Description: Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management of primary non-response and secondary loss of response to biologics, while cumulative evidence suggests that proactive TDM is efficacious for optimizing anti-tumour necrosis factor (anti-TNF) therapy in patients with IBD. Proactive TDM can be very useful for optimizing biological therapy in specific IBD populations, such as pregnant women as well as patients with perianal fistulizing Crohn’s disease and acute severe ulcerative colitis who are characterized by high drug clearance. Preliminary data suggest that proactive TDM may also have a role in de-escalating anti-TNF therapy in patients in clinical remission including stopping the immunomodulator when combined with anti-TNF therapy. However, several knowledge gaps and limitations hinder the wide implementation of TDM in clinical practice, including the optimal drug concentration to target the lag time between sampling and results and the lack of harmonization of TDM assays. Recent advances regarding the role of TDM include the use of rapid point-of-care assays and the incorporation of model-informed precision dosing. The aim of this Special Issue is to highlight the clinical utility of TDM and discuss the barriers and recent advances of TDM of biologics in IBD and other IMID.
    Keywords: ulcerative colitis ; Crohn&rsquo ; s disease ; inflammatory bowel disease ; infliximab ; adalimumab ; certolizumab pegol ; golimumab ; vedolizumab ; ustekinumab ; therapeutic drug monitoring ; immunogenicity ; rheumatoid arthritis ; ankylosing spondylitis ; psoriasis ; clearance ; model informed precision dosing ; bic Book Industry Communication::M Medicine
    Language: English
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  • 8
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-03-22
    Description: Politik soll ihre Entscheidungen nicht nur sachgerecht und gemäß den rechtlichen Rahmenbedingungen treffen, sondern ebenso den Ansprüchen der Moralität genügen. Anhand der vier Themen Moral, Terrorismus, Globalisierung und Demokratie zeigen renommierte Experten allgemeinverständlich auf, welche Herausforderungen damit für Politik und Ethik verbunden sind. Mit Beiträgen von Moritz Leuenberger, Herfried Münkler, Francis Cheneval und Julian Nida-Rümelin.
    Keywords: Ethik ; Politik ; Demokratie ; Sicherheit ; Globalisierung ; Politische Theorie ; Politische Philosophie ; Politikwissenschaft ; Philosophie ; Ethics ; Politics ; Democracy ; Globalization ; Political Theory ; Political Philosophy ; Political Science ; Philosophy ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPA Political science & theory ; bic Book Industry Communication::H Humanities::HP Philosophy::HPQ Ethics & moral philosophy ; bic Book Industry Communication::H Humanities::HP Philosophy::HPS Social & political philosophy
    Language: German
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the IBD classification are ulcerative colitis (UC) and Crohn’s disease (CD), sharing similarities but exhibiting distinct differences, sometimes making their discrimination challenging.A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by the robust and persistent infiltration of immune cells and compromised intestinal barrier integrity, leading to a phenomenon known as “leaky gut.” Inflammation can manifest acutely or chronically, known as relapsing, and can increase in severity over time, thereby causing life-long morbidities and reduced quality of life for affected individuals, underscoring the need for a deeper comprehension of the molecular contributors to disease pathogenesis and progression.
    Keywords: inflammatory bowel diseases ; cell autofluorescence ; immune cells ; NADH ; FAD ; flow cytometry ; multiphoton microscopy ; colitis ; colitis-associated cancer ; inflammatory bowel disease ; colorectal cancer ; colon adenocarcinoma ; ulcerative colitis ; Crohn’s disease ; cDNA microarray ; transciptomics analysis ; microarray ; inflammatory bowel diseases (IBDs) ; vasculature ; angiogenesis ; gut vascular barrier ; vessel permeability ; epithelial barrier ; homeostasis ; acetylcholine ; muscarinic receptor ; non-neuronal acetylcholine ; mucosal wound healing ; ferroptosis ; leaky gut ; inflammatory bowel disease (IBD) ; triple-culture ; Caco-2 ; HT29-MTX-E12 ; THP-1 ; monocyte-derived macrophage ; inflammation ; TEER ; FITC-dextran 4 kDa (FD4) ; pro-inflammatory cytokines ; HIF-1α ; PHD2 ; AKT ; intestinal epithelial cells ; probiotics ; LPS ; antigen-specific T-cells ; celiac disease ; gliadin ; IBD ; food antigens ; intestinal Behcet’s disease ; immune mechanism ; biological agents ; claudin ; tight junctions ; barrier function ; gut ; ZO-1 ; actin ; cell migration ; cell division ; colon cancer ; PMNs ; LDs ; FOXO3 ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 10
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    transcript Verlag
    Publication Date: 2024-03-29
    Description: Rechtspopulismus und Autoritarismus, Auseinandersetzungen um »Identitätspolitik«, die Digitalisierung der öffentlichen Debatte und die Macht von Verschwörungstheorien führen zu tiefgreifenden sozialen, kulturellen und politischen Transformationsprozessen. Für die Untersuchung dieser Transformationen sind die Theorien des Politischen und der radikalen Demokratie besonders geeignet, da sie die grundsätzliche Fragilität der liberalen Ordnung analysieren. Fraglich ist jedoch, ob die radikaldemokratische Forderung nach einer Disruption der liberalen Ordnung die richtige Antwort auf die beschriebenen Transformationen ist. Die Beiträge unternehmen eine kritische Revision der Theorien des Politischen und erschließen damit das gegenwartsanalytische Potential radikaldemokratischer Ansätze für die 2020er Jahre.
    Keywords: Demokratie ; Radikale Demokratie ; Populismus ; Kapitalismus ; Partizipation ; Liberalismus ; Digitalisierung ; Identitätspolitik ; Rechtspopulismus ; Autoritarismus ; Verschwörungstheorie ; Politik ; Politische Theorie ; Politische Philosophie ; Poststrukturalismus ; Politikwissenschaft ; Democracy ; Radical Democracy ; Populism ; Capitalism ; Participation ; Liberalism ; Digitalization ; Identity Politics ; Right-wing-populism ; Authoritarianism ; Conspiracy Theory ; Politics ; Political Theory ; Political Philosophy ; Post-structuralism ; Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTS Social and political philosophy ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPH Political structure and processes::JPHV Political structures: democracy
    Language: German
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  • 11
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    Hamburger Edition
    Publication Date: 2024-04-04
    Description: Der G20-Gipfel 2017 in Hamburg ist nicht wegen der vielfältigen Protestformen oder der dort verhandelten Themen in Erinnerung geblieben, sondern vor allem wegen der gewaltsamen Ausschreitungen und Konfrontationen mit der Polizei. Die Beiträge dieses Bandes analysieren die Dynamiken der damaligen Eskalation. Dabei rekonstruieren die Autor:innen Vorgeschichte und Verlauf der Gewalt und die Rolle der (sozialen) Medien, sie nehmen die politische sowie die rechtliche Aufarbeitung in den Blick und beleuchten den polizeilichen Umgang mit Protest. Die Ereignisse um den G20-Gipfel in Hamburg werden so zu einer analytischen Linse, um Eskalationsprozesse und das Verhältnis von Protest und Gewalt besser zu verstehen. Mit Beiträgen von u.a. aus dem Forschungsprojekt Mapping #NoG20 und von Rafael Behr, Priska Daphi, Donatella della Porta, Wilhelm Heitmeyer, Wolfgang Knöbl, Jan Philipp Reemtsma und Matthias Wahlström.
    Keywords: Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: German
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  • 12
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-03-22
    Description: Das ambivalente Verhältnis zwischen Politik und Gewalt - obwohl gegenwärtig von großer Brisanz - bleibt bislang in der Politischen Philosophie begrifflich und konzeptionell unscharf bestimmt. Dieses Buch knüpft an unterschiedliche disziplinäre und subdisziplinäre Perspektiven über die Politische Philosophie hinaus an - etwa an Überlegungen aus den Internationalen Beziehungen oder der Soziologie. So entsteht eine genauere und kritische Analyse zu einem Thema, das die Politik immer wieder herausfordert.
    Keywords: Politische Philosophie ; Politikwissenschaft ; Gewalt ; Internationale Beziehungen ; Politik ; Politische Theorie ; Konfliktforschung ; Philosophie ; Political Philosophy ; Political Science ; Violence ; Politics ; Political Theory ; Conflict Studies ; Philosophy ; bic Book Industry Communication::H Humanities::HP Philosophy::HPS Social & political philosophy ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPA Political science & theory ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFE Violence in society
    Language: German
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  • 13
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-04-08
    Description: Wenige politische Denker haben den internationalen politik- und sozialwissenschaftlichen Theoriediskurs der vergangenen Jahre so beeinflusst wie Chantal Mouffe und Ernesto Laclau - über Paradigmengrenzen hinweg. Beide verknüpfen neo-gramscianische, (post-)strukturalistische und psychoanalytische Theorieelemente und ermöglichen damit einerseits eine Erklärung von Ereignissen des politisch-diskursiven Geschehens, insbesondere der Ausbildung von Hegemonien, und andererseits eine normative Theorie der agonalen Demokratie. Die Beiträge dieses Bandes geben einen Überblick über wesentliche Denkfiguren von Laclau und Mouffe, setzen sich mit diesen kritisch auseinander und zeigen methodische und empirische Anschlussmöglichkeiten auf. Dieser Band enthält u.a. Originaltexte von Ernesto Laclau und Chantal Mouffe.
    Keywords: Ernesto Laclau ; Chantal Mouffe ; Demokratietheorie ; Hegemonie ; Politik ; Politische Philosophie ; Politische Theorie ; Poststrukturalismus ; Politikwissenschaft ; Philosophie ; Politics ; Political Philosophy ; Political Theory ; Post-structuralism ; Political Science ; Philosophy ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTS Social and political philosophy ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTS Social and political philosophy ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory
    Language: German
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Recent years have seen growing interest in equine lung and heart health, and advances in technology and a focus on equine welfare have driven this research. This Special Issue explores novel diagnostic and therapeutic approaches, including imaging techniques and lung function testing, immunological features, and immunomodulatory treatments for equine asthma and common racehorse respiratory issues. Moreover, it reports on novel echocardiography data of donkeys. This collection offers valuable insights into equine cardio-respiratory medicine.
    Keywords: equine asthma ; exercise-induced pulmonary hemorrhage ; racehorse respiratory medicine ; donkey cardiology ; bic Book Industry Communication::M Medicine
    Language: English
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on treating the associated comorbidities and complications of cerebral palsy. Increased prescription of technology means that we are treating some comorbidities of cerebral palsy earlier or even pre-emptively. Increased life expectancy, compared with 20 years ago, means that we are also seeing even later complications of cerebral palsy. However, increased access to intensive medical care at home, non-invasive ventilation, and total parenteral nutrition now exist. There is also greater engagement with the perspectives and expectations of parents/carers and children. As society begins to discuss mental health more openly, we are also starting to recognise the significant two-way associations between disability and mental health. Ethical consultation may be warranted when harm with treatment exceeds the benefit. As we prepare children with cerebral palsy for adulthood, there is more thought and discussion around issues such as pain, mental health, quality of life, independence, and participation. Researchers in the field of cerebral palsy have contributed original articles and reviews which help build our evidence base to guide shared decision making.
    Keywords: mental health ; anxiety ; depression ; cerebral palsy ; adolescence ; young adults ; young people ; adolescents ; unmet need ; health services ; physical therapy ; occupational therapy ; fracture ; bone fragility ; mortality ; epidemiology ; age-adjusted mortality rates ; death certificate ; medical education ; severe neurological impairment ; scoliosis ; shared decision-making ; respiratory ; hospitalisations ; antibiotics ; Indigenous ; inequities ; cell therapies ; stem cells ; comorbidities ; outcome measures ; clinical studies ; inflammation ; biomarker ; comorbidity ; scoping review ; co-design ; intervention ; participation ; involvement matrix ; public and patient involvement ; early intervention ; infant vocalisations ; infants ; single-subject research design ; CP ; infant ; stress ; parents ; fathers ; parent–infant interaction ; representations ; epilepsy ; children ; neuroimaging ; seizure outcome ; Sialorrhea ; submandibular duct relocation ; postoperative management ; ultrasound ; piecewise model ; muscle volume ; cross-sectional area ; GMFCS ; upper limb ; sensory function ; bimanual intensive functional therapy ; hand function ; associated impairment ; register ; low- and middle-income country ; hip displacement ; hip surveillance ; adductor-psoas release ; hip reconstruction ; guided growth ; salvage surgery ; disability ; emotion regulation ; atropine ; sialorrhea ; pediatric ; drooling ; sublingual ; developmental disorders ; neurodevelopmental disorders ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 16
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    transcript Verlag
    Publication Date: 2024-04-06
    Description: Die deutschen Gewerkschaften sind massiv von den Auswirkungen der Digitalisierung der Arbeitswelt betroffen. Ihre Organisations- und Durchsetzungsfähigkeit wird ebenso strapaziert wie ihr Anspruch auf eine möglichst umfassende Repräsentation der lohnabhängig Beschäftigten und Arbeitenden. Vor diesem Hintergrund diskutieren die Beiträger*innen die theoretischen Möglichkeiten und praktischen Erfahrungen mit der Digitalisierung von Gegenmacht aus gewerkschaftlicher und sozialwissenschaftlicher Perspektive. Dazu gehören u.a. Formen des Arbeitskampfes im digitalen Sektor und neue, widerständige Praktiken im Internet oder in der digitalen Infrastruktur von Unternehmen und Konzernen.
    Keywords: Gewerkschaft ; Digitalisierung ; Macht ; Gegenmacht ; Demokratie ; Solidarität ; Politischer Konflikt ; Aktivismus ; Theorie ; Arbeitskampf ; Betriebsrat ; Internet ; Infrastruktur ; Unternehmen ; Konzern ; Plattformkapitalismus ; Digitalökonomie ; Arbeit ; Politik ; Zivilgesellschaft ; Policy ; Arbeits- und Industriesoziologie ; Arbeitsökonomie ; Politikwissenschaft ; Labour Union ; Digitalization ; Power ; Democracy ; Solidarity ; Activism ; Theory ; Labour Struggle ; Works Council ; Infrastructure ; Work ; Politics ; Civil Society ; Sociology of Work and Industry ; Labour Economics ; Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPW Political activism / Political engagement ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPQ Central / national / federal government::JPQB Central / national / federal government policies ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBL Sociology: work and labour
    Language: German
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  • 17
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint entails descriptions of novel issues and challenges for primary mental healthcare regarding both general and vulnerable populations on a global scale. It is intended for health professionals and all who are interested in mental health care at the primary level.
    Keywords: depression ; sense of coherence ; burnout ; COVID-19 ; nurses ; medication adherence ; mental health nurses ; tacit knowledge ; schizophrenia ; sensory processing sensitivity ; environmental sensitivity ; university students ; nursing ; scale ; somatization ; number of diseases ; coping strategies ; sex ; aggression ; alexithymia ; comprehensibility ; quality of life ; family caregivers ; students ; medical ; psychological problem ; undergraduate ; Saudi Arabia ; n/a ; prospect theory ; applied psychology ; health ; decision making ; behavior ; prevention ; multiple sclerosis ; Beck depression inventory ; anxiety ; fatigue ; mediation ; lawyers ; suicidal ideation ; occupational stress ; loneliness ; perceived stress ; mental health ; work overcommitment ; mental health care ; adolescence ; internalizing/externalizing problems ; social skills ; neurodevelopmental disorders ; filmmaking intervention ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
    Language: English
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint includes studies on diagnosing, evaluating and managing the pathologies diagnosed during pregnancy. The information provided in these pages is helpful for specialists in obstetrics and gynaecology but also for other medical specialities involved in treating pregnant women with associated pathologies. Studying the articles in the reprint could contribute to improving case management.
    Keywords: pregnancy ; fetus prenatal care ; high-risk ; pathology ; bic Book Industry Communication::M Medicine
    Language: English
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The aim of this Special Issue is to specify relevant principles of mathematics and mechanics in order to explore and understand biological problems. We summarize the most important parameters that influence human performance and that are related to the health sciences for all age groups, throughout their lives. We present papers that aim to introduce the latest research in the fields of health, quality-of-life improvement, and sport rehabilitation and that summarize their recommendations for best practice. The aim for this Special Issue is, therefore, to effectively combine and coordinate research and results in order to understand and improve human movement in medicine, sports, and at work.
    Keywords: tendinopathy ; Achilles tendon ; hyaluronic acid ; viscoelastic properties ; isometric contraction ; matrix metalloproteinase 3 ; interleukin-1beta ; fascia ; chronic low back pain ; myofascial release ; quality of life ; older adults ; oldest-old ; measurement invariance ; SHARE European Survey ; therapeutic exercises ; chronic neck pain ; scapular dyskinesia ; DOMS ; vibration ; post-exercise muscle damage ; physical exercise ; recovery ; women’s rugby ; anthropometry ; body composition ; adiposity ; somatotype ; lower-body strength ; accelerometry ; falls ; squat jump ; syndesmosis ; anterior inferior tibiofibular ligament ; high ankle sprain ; rotational instability ; posterior malleolus ; stabilization ; anatomic repair ; syndesmotic screw ; suture-button ; internal bracing ; treatment algorithm ; cardiac rehabilitation ; peripheral artery disease ; COVID-19 ; intermittent claudication ; review ; pressotherapy ; compression ; regeneration ; return-to-play ; rotator cuff repair ; shoulder injuries ; shoulder surgery ; shoulder assessment ; chronic obstructive pulmonary disease ; COPD ; acupuncture ; acupuncture therapy ; acupuncture treatment ; health-related quality of life ; anterior knee laxity ; stiffness ; general joint laxity ; genu recurvatum ; low back pain ; physical activity ; trunk alignment ; rasterstereographic system ; young males ; tissue flossing ; floss band ; vascular occlusion ; muscle strength ; muscle endurance ; warm-up ; TECAR therapy ; high-intensity laser therapy ; manual therapy ; muscle disorders ; hemophilia ; knee ; virtual reality exposure therapy ; joint pain ; physiotherapy ; daily physical function ; middle-aged and older adults ; CHARLS ; aging ; appendicular muscle mass ; inflammaging ; biomarkers ; adiponectin ; sarcopenia ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The 3D analysis of human movement aims to objectively and quantitatively assess motor functions and alterations. It is a valuable method for sport scientists, coaches, and clinicians to evaluate sport performance, common movements, and alterations. The feasibility of 3D analysis is increasing because it can be adopted both in a laboratory setting or directly in the field, in static or dynamic conditions, and for physiological or pathological movements. This evaluation technique can be adopted for many people, including children, adolescents, adults, and older people, whether they are sedentary or athletes and whether they are healthy or motor-impaired people.
    Keywords: virtual reality ; augmented reality ; lifelogging ; mirror world ; health ; posture training ; feedback ; COVID-19 ; neck-shoulder-region ; shoulder protraction ; upper crossed syndrome ; posture weakness ; physical inactivity ; sedentary behavior ; soccer ; climbing ; exhaustion ; fatigue ; training ; machine learning ; sports ; gender ; data mining ; artificial intelligence ; posture ; reproducibility ; mobile app ; movement ; kinesiology ; sport performance ; inertial sensor ; inertial sensor device ; inertial measurement unit ; training load ; external load ; physical demand ; handstand ; postural control ; postural balance ; sEMG ; stabilometric assessment ; exercise ; Nordic walking ; walking ; 3D kinematics ; biomechanics ; gait analysis ; kyphosis ; spinal mouse ; photogrammetry ; postural evaluation ; bicycle ; cyclists ; saddle pressure ; perineal pressure ; urogenital system ; injury prevention ; cervical ROM ; elastic taping ; neck pain ; musculoskeletal health ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the orthopedic surgical field, knee surgeries, including articular cartilage repair procedures, meniscus surgery, ligament reconstruction surgery, osteotomy surgery, and partial/total knee arthroplasty surgery, have made great advances over the last few decades. This Special Issue highlights and focuses on the surgical concepts and techniques, decision-making processes, perioperative management protocols, and clinical outcomes of the recent various advanced knee surgery procedures.
    Keywords: high tibial osteotomy ; TomoFix ; plate position ; anatomical conformity ; dual-energy CT ; Hounsfield unit ; bone mineral density ; volumetric phantomless BMD ; opportunistic CT ; orthopedic surgeon ; planning ; survey ; total knee arthroplasty ; unicompartmental knee arthroplasty ; anterior cruciate ligament ; reconstruction ; bone tunnel widening ; adjustable-loop device ; interference screw ; hamstring tendon ; autograft ; tibial component alignment ; radiographic references ; extramedullary system ; tranexamic acid ; clamping time ; transfusion ; estimated blood loss ; continuous cold flow therapy ; cryotherapy ; pain ; opioids consumption ; patient satisfaction ; bone marrow lesion ; knee ; meniscus ; root tear ; root repair ; femorotibial joint ; chondromalacia ; aging ; body mass index ; magnetic resonance imaging ; automated detection ; detection algorithm ; deep learning ; venous thromboembolism ; medial collateral ligament ; strain ; video extensometer ; medial opening-wedge high tibial osteotomy ; central sensitization ; patient-reported outcomes ; osteotomy site pain ; minimal clinically important difference ; human umbilical cord blood derived mesenchymal stem cells ; cartilage regeneration ; cartilage repair ; osteoarthritis treatment ; stem cell therapy ; Outerbridge ; degeneration ; spacer block ; intramedullary rod ; femorotibial congruence ; unicompartmental arthroplasty ; osteoarthritis ; cartilage ; stem cells ; umbilical cord blood ; femur fracture ; polyethylene insert ; osteoporosis ; multivariate logistic analysis ; atelocollagen ; microfracture ; ACIC ; bone marrow aspirate concentrate ; human umbilical cord blood-derived mesenchymal stem cells ; knee osteoarthritis ; loosening ; arthroplasty ; machine learning ; transfer learning ; review ; prosthesis ; meniscus root ; medial meniscus posterior root ; medial meniscus posterior root tear ; meniscus root repair ; transtibial pull-out repair ; bone tunnel enlargement ; anterior cruciate ligament reconstruction ; landmark ; lateral tibial spine ; anatomy ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Over the years, digestive endoscopy has gone through a revolution. With different technological improvements, its diagnostic role is indeed becoming more and more sophisticated and is even moving closer to pathological evaluation. Above all, its therapeutic purpose is to date the first line of treatment for several gastrointestinal diseases. Importantly, the role of digestive endoscopy is also crossing over the mere concept of the GI tract and digestive diseases and will probably find a place in a more holistic concept of health. In this Special Issue, several emerging techniques are addressed, highlighting how endoscopy is emerging as a minimally invasive treatment procedure for several gastrointestinal diseases and post-surgical complications. However, crucial to this is the safety of all endoscopic processes, starting from endoscopic suites to the management of intra- and post-procedural complications.
    Keywords: interventional endoscopy, ERCP, cholangioscopy, biliopancreatic endoscopy, CH-EUS, radiofrequency ablation, necrosectomy, locoregional treatment, bariatric endoscopy, artificial intelligence ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Modern medical imaging systems provide information about the patient's health condition. Their precision, resolution and sensitivity are increasing, and new possibilities of differentiating the condition of tissue are constantly appearing. These advances are also taking place in musculoskeletal imaging. Increasingly accurate imaging in various modalities allows us to discover new relationships between the image and the diagnosis. It is therefore important to use all this information to best serve the patient. That is why research related to the analysis of medical images is so important, because it allows us to indicate what is invisible to the naked eye or to quantify what has so far been measured by humans or subject to discretionary assessment. This collection includes 25 works related to the analysis of images created during diagnostics of the musculoskeletal system using various modalities—from X-ray and fluoroscopy to conventional or spectral computed tomography, magnetic resonance imaging, ultrasound, elastography, PET/CT and systems for analyzing patient mechanics. Research was carried out related to the detection of various conditions, parameterization of clinical and population phenomena, and detection of image–clinical condition relationships. Despite the current popularity of machine learning techniques, the collection is dominated by classic engineering methods related to image processing. Several works use textural analysis, which has not been appreciated so far, which is particularly related to the imaging of the structure, especially of bones.
    Keywords: bone imaging, musculoskeletal imaging, image processing, image analysis, segmentation, textural analysis, machine learning ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Pain biomarkers are biological indicators or measurable characteristics that can provide information about the presence, severity, or underlying mechanisms of pain. They are valuable for several reasons: Diagnosis and differential diagnosis: Biomarkers can help in the diagnosis of various pain conditions and differentiate between different types of pain, such as neuropathic, inflammatory, or nociceptive pain. This can lead to more accurate and timely diagnoses, which in turn can improve patient care. Monitoring treatment efficacy: Pain biomarkers can be used to track how well treatments are working for individuals suffering from chronic pain conditions. This allows healthcare providers to make informed decisions about adjusting treatment plans, optimizing pain management, and avoiding unnecessary or ineffective interventions. Drug development and testing: Biomarkers play a crucial role in the development of new pain medications and therapies. They can help researchers identify potential drug targets, screen compounds for their pain-relieving properties, and assess the safety and efficacy of experimental treatments in clinical trials. Personalized medicine: Pain biomarkers may, in a future, contribute to treatments, tailored to an individual's unique genetic and biological disposition. Reducing opioid misuse: By using biomarkers to assess pain and treatment responses, healthcare providers can make more informed decisions about opioid prescriptions, potentially reducing the overuse and abuse of these medications.
    Keywords: analgesia ; biomarker ; CSF ; cytokine ; inflammation ; neuropathy ; neurotransmitter ; pain ; QoL ; sensitization ; sensory ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-04-08
    Description: Wer ist der existenzielle Republikaner? Er ist ein exemplarisches Beispiel für jemanden, der das »Wagnis der Öffentlichkeit« (Karl Jaspers) eingeht - das beste Beispiel eines Citoyens. Getrieben von einer Liebe zur Welt, die er allerdings nur durch seine Freiheit und in seinem Handeln ausdrücken kann. Gerade diese liebende Handlung ist heute gefordert - egal ob auf Demonstrationen gegen Donald Trump oder für eine gerechtere Welt, egal ob durch Parteibeitritte oder dem Schreiben von Essays für Zeitungen. Es ist Zeit, sich für eine bessere Welt einzusetzen. Nils Heisterhagen muntert zur republikanischen Freiheit auf.
    Keywords: Republikanismus ; Liberalismus ; Liebe ; Freiheit ; Hannah Arendt ; Karl Jaspers ; Citoyen ; Demokratie ; Donald Trump ; Philosophie ; Politik ; Politische Philosophie ; Politische Theorie ; Politikwissenschaft ; Republicanism ; Liberalism ; Love ; Liberty ; Democracy ; Philosophy ; Politics ; Political Philosophy ; Political Theory ; Political Science ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTS Social and political philosophy ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTS Social and political philosophy ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory
    Language: German
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-04-04
    Description: Welchen Platz nehmen die Kämpfe von Gewerkschaften und anderen sozialen Bewegungen in der kollektiven Erinnerung ein? Wie ist es um deren Errungenschaften bestellt? Was stärkt die Werte sozialer Demokratie in der Erinnerungskultur? Die Beiträger*innen des Bandes bieten erstmals ausführliche Einblicke in die Erinnerungsgeschichte sozialer Kämpfe und Auseinandersetzungen um Gleichheit, Freiheit und Gerechtigkeit. An wen oder an was erinnert wurde, erweist sich dabei immer auch als Machtfrage, als Kampf um Inklusion und Exklusion. Dieser Band stellt somit nicht nur einen ersten Schritt auf dem Weg zu einer Erinnerungsgeschichte sozialer Demokratie dar, sondern leistet auch einen Beitrag zur politischen Debatte der Gegenwart.
    Keywords: Soziale Demokratie ; Arbeiter*innenbewegung ; Gewerkschaften ; Soziale Bewegungen ; Kollektive Erinnerung ; Erinnerungskulturen ; Deutschland ; 20. Jahrhundert ; 21. Jahrhundert ; Politik ; Erinnerungskultur ; Politische Parteien ; Politische Ideologien ; Sozialgeschichte ; Politikwissenschaft ; Social Democracy ; Trade Unions ; Social Movements ; Collective Memory ; Cultures of Remembrance ; Germany ; 20th Century ; 21st Century ; Politics ; Memory Culture ; Political Parties ; Political Ideologies ; Social History ; Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPL Political parties and party platforms ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPF Political ideologies and movements
    Language: German
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on the comprehensive understanding and novel treatments in the realm of cornea and ocular surface diseases. Ranging from the relatively benign manifestations of keratoconjunctivitis sicca to more critical conditions such as corneal ulcers, ocular surface diseases pose a considerable challenge in clinical ophthalmology. Such conditions can severely compromise the transparency of the cornea, often necessitating interventions such as keratoplasty. A significant emphasis of this edition is on the paramount importance of pre-surgical optimization. A successful keratoplasty is often predicated on the health of the ocular surface. Through a series of insightful articles, the importance of enhancing tear function, rehabilitating the normal lid anatomy, and ensuring a robust limbal stem cell supply is elucidated. Properly addressing these factors has a direct bearing on the success rate of the subsequent surgical intervention. Another highlight of this Special Issue is the presentation of cutting-edge treatments. Researchers from around the globe share their findings, detailing advancements in both surgical and non-surgical treatments. These range from innovative surgical techniques and tools to groundbreaking pharmaceutical agents that hold promise in managing and possibly reversing some of these conditions. In summary, this Special Issue serves as a repository of the latest knowledge in the management of cornea and ocular surface diseases, aimed at both the seasoned ophthalmologist and budding researchers in the field.
    Keywords: cornea ; ocular surface disease ; dry eye ; corneal ulcer ; keratoplasty ; bic Book Industry Communication::M Medicine
    Language: English
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    Publication Date: 2024-03-15
    Description: Wie denken Beschäftigte, zum Beispiel in der Industrie, im Handel oder in Krankenhäusern, über Ungleichheit, Parteien oder die Klimakrise? Welche Politik wünschen sie sich und was stört sie? Thomas E. Goes widmet sich diesen Fragen empirisch, um die Erfolgschancen eines Grünen Sozialismus auszuloten. Im Zentrum steht dabei das vorherrschende Alltagsbewusstsein der Arbeiter*innen: Für eine breite Unterstützung muss die Forderung nach Gleichheit, mehr Demokratie und einem wirksamen Klimaschutz hier anknüpfen. Nur so bieten sich Möglichkeiten, eine sozial und ökologisch gerechte Politik nicht nur in der Theorie, sondern auch in der Praxis umzusetzen.
    Keywords: Grüner Sozialismus ; Arbeit ; Arbeiter ; Politik ; Klasse ; Klima ; Klimakrise ; Sozialismus ; Ökosozialismus ; Staat ; Wohlfahrtsstaat ; Demokratie ; Gleichheit ; Partei ; Natur ; Soziale Ungleichheit ; Politische Soziologie ; Umweltsoziologie ; Politikwissenschaft ; Soziologie ; Green Socialism ; Work ; Politics ; Class ; Climate ; Climate Crisis ; Socialism ; Eco-scialism ; State ; Welfare State ; Democracy ; Equality ; Party ; Nature ; Social Inequality ; Political Sociology ; Environmental Sociology ; Political Science ; Sociology ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNT Social impact of environmental issues ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFM Social mobility
    Language: German
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-03-22
    Description: Obschon Städte zurzeit vor allem durch ihre drastischen Probleme in unser Bewusstsein treten, ist es sinnvoll, auch nach der urbanen Wende an einer Vorstellung von der »guten Stadt« festzuhalten. Dieser Topos bildet eine Konstante der normativen Reflexion der menschlichen Lebensform, die dadurch, dass die Stadt das menschliche Habitat par excellence geworden ist, neue Bedeutung erlangt. Durch eine kritische Rekonstruktion der Geschichte von der »guten Stadt« anhand klassischer sowie zeitgenössischer Beiträge - von Platons Kallipolis bis zu von Borries' Klimakapseln - zeigt Mara-Daria Cojocaru, wie ein gewisser Rest-Utopismus das gesellschaftliche Handeln in den Städten begleiten kann. Sie zeigt: Nicht die gebaute Umwelt bringt bedeutsame Formen von Gesellschaft hervor - vielmehr verhält es sich umgekehrt.
    Keywords: Stadt ; Normativität ; Urbanität ; Utopie ; Politische Erzählungen ; Philosophische Anthropologie ; Narrativität ; Politik ; Politische Philosophie ; Sozialphilosophie ; Urban Studies ; Politikwissenschaft ; Philosophie ; Urbanity ; Philosophical Anthropology ; Politics ; Political Philosophy ; Social Philosophy ; Political Science ; Philosophy ; bic Book Industry Communication::H Humanities::HP Philosophy::HPS Social & political philosophy ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFS Social groups::JFSG Urban communities
    Language: German
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    Agenda Publishing
    Publication Date: 2024-03-07
    Description: Climate change is increasingly contested on financial terms. Different actors are advancing competing climate visions and interests by adopting financial positions. International institutions urge action by identifying financing gaps needed to meet climate targets. The finance sector claims it holds the key to unlocking money needed for climate investment. Activists expose greenwashing while using financial tactics to undermine fossil fuels. Vulnerable countries demand wealthy governments repay historical climate debts.This book offers an accessible and critical guide to the political economy and economic geography of climate finance. It identifies six competing ""positions"" of climate finance to make sense of the array of financial instruments, institutions and ideas that are remaking the relationship between capitalism and climate change. Using a wide range of case studies, from green bonds, to divestment, carbon offsetting, climate tech, central banks, and international climate funds, the authors show how climate finance is shaping our collective climate futures.
    Keywords: Business & Economics ; Development ; Sustainable Development ; Political Science ; Public Policy ; Economic Policy ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPQ Central government::JPQB Central government policies
    Language: English
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    Publication Date: 2024-01-08
    Description: This reprint, entitled “Management of Acute and Chronic Complications of Lysosomal Storage Diseases in Children and Adults: Current Practice and Future Opportunities”, covers broad aspects of this group of rare diseases. The first theme includes articles on the management of pain, corneal clouding, gastrointestinal and airway diseases in Mucopolysaccharidoses and Mucolipidoses, and the evaluation of dysphonia in Pompe disease. Additionally, attention deficit and ADHD and the management of atherosclerosis in Fabry disease are considered here. The second theme includes diagnostic conundrums in lysosomal storage diseases, e.g., the prenatal diagnosis of Gaucher disease during pregnancy, the diagnosis of secondary hyperparathyroidism in Mucolipidoses, and the application of the new biomarker “plasma neurofilament light” in Niemann Pick C disease, as well as the correlation of enzyme activity with molecular diagnosis in Pompe disease. The articles in the third theme describe the impact of therapies on clinical outcomes. For example, a systematic review of the impact of enzyme replacement therapy on late-onset Pompe disease and trehalose use on Niemann Pick A and B is included. The remaining articles describe the NHS processes for overcoming challenges resulting from the COVID-19 pandemic and the differences in the transition from paediatric to adult services between different countries.
    Keywords: Mucopolysaccharidosis ; corneal clouding ; penetrating keratoplasty ; deep anterior lamellar keratoplasty ; mucopolysaccharidoses ; airway ; obstruction ; management ; Fabry disease ; attention ; Attention Deficit/Hyperactivity ; cognition ; late-onset Pompe disease ; gastrointestinal ; smooth muscles ; PROMIS–GI symptom scales ; GAAKO mice ; glycogen storage disorder ; translational research ; patient-reported outcomes measures ; mucopolysaccharidosis ; MPS ; disease manifestations ; symptoms ; morbidity ; spine disease ; anaesthesia ; perioperative complications ; surgery ; pompe disease ; speech ; voice ; dysphonia ; acoustic ; auditory-perceptual ; GRBAS ; respiratory ; Pompe disease ; gene panel sequencing ; alpha-glucosidase ; GAA ; dried-blood spots ; fabry disease ; neuropathic pain ; depression ; Fabry ; atherosclerosis ; ischaemia ; perfusion ; angina ; Sanfilippo syndrome ; mortality ; Niemann–Pick C ; neurofilament light ; biomarkers ; neurological disease ; glycogen storage disease type II ; enzyme replacement therapy ; COVID-19 ; inherited metabolic disorders ; rare autoinflammatory diseases ; health care providers ; Gaucher disease ; NIHF ; perinatal-lethal Gaucher disease ; PLGD ; ichthyosis ; GBA gene ; airway management ; radiology ; hyoid bone ; chin ; intubation ; intratracheal ; lysosomal storage disease (LSD) ; Niemann–Pick type A ; Niemann–Pick type B ; acid sphingomyelinase ; sphingolipid deposition ; trehalose ; mucolipidosis type II ; ML II ; I-cell disease ; hyperparathyroidism ; mucolipidosis ; ML ; MLII ; transition service ; adult metabolic medicine ; collaboration ; challenges ; inherited metabolic diseases ; healthcare systems ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Molecular toxicology is a field that investigates the interactions between chemical or biological molecules and organisms at the molecular level. In this Special Issue, we focus on the toxic effects and mechanisms of action of chemical and biological molecules, will be of great interest of readers in molecular toxicology and applied pharmacology.
    Keywords: smoking ; inflammatory ; cytokine ; human serum ; GO ; PRRSV ; FT-SPR ; sensitization ; NNK ; nicotine ; cytotoxicity ; genotoxicity ; cytochrome P450 2A13 ; Aspergillus flavus ; aflatoxins B1 ; carcinogen ; Surface-Enhanced Raman Scattering ; colloidal Au nanoparticles ; portable Raman spectrometer ; Euphorbia semen ; Euphorbia factors ; transcriptome ; RNA sequencing ; bioinformatics ; gene structure ; neuroblast differentiation-associated protein AHNAK ; hepatocellular carcinoma (HCC) ; insulin-like growth factor 1 receptor (IGF-1R) ; interactome ; field cancerization ; 8–17 DNAzyme ; gene silencing ; catalysis ; antisense ; chemical modifications ; 6-cyclohexyl methyl-β-D-maltoside ; transduction efficiency ; conditionally replicative adenovirus ; lethal effect ; gene therapy ; PBDE ; immunotoxicity ; macrophage ; reactive oxygen species ; apoptosis ; immune function ; breast cancer ; signature ; aging ; cancer ; nomogram ; immunotherapy ; tumor mutation burden ; doxorubicin ; Toll-like receptor 4 ; cardiotoxicity ; heart ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology::MMGT Medical toxicology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, we have gathered high-level research papers from all over the world. We would like to thank all researchers for their commitment to the field. From diagnostic ultrasound of different fetal conditions to advanced cardiovascular imaging leading to fetal MRI and from serum markers and biomarkers in maternal and fetal conditions to new modalities in fetal therapy, this Special Issue covers a large scale view of the present spectrum of modern perinatal medicine. Again, a warm thank you to all contributors.
    Keywords: fetal echocardiography ; fetal abnormalities ; fetal therapy ; genetic testing, prenatal medicine ; bic Book Industry Communication::M Medicine
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    Hamburger Edition
    Publication Date: 2024-03-07
    Description: Der politischen Unabhängigkeit der Medien wird in heutigen Demokratien höchste Bedeutung zugemessen. Doch weder die Demokratie noch unabhängige Medien sind selbstverständlich – und sie waren es auch noch nie. An Beispielen aus Deutschland und Großbritannien beschreibt Ute Daniel, wie wechselhaft und unvorhersehbar die Beziehungen zwischen Politiker_innen und politischen Journalist_innen sind, wie kontextabhängig das Kräftespiel. Und sie zeigt, dass dessen vergangene Ausprägungen oft gar nichts an aktueller Relevanz eingebüßt haben. Auch heute beschäftigen sich demokratische Gesellschaften mit journalistischem Informantenschutz und der Bedeutung von Whistleblowern, mit dem Einfluss der Medienmogule auf die Politik und den gesetzlichen Rahmenbedingungen für elektronische Massenmedien.
    Keywords: Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government
    Language: German
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-03-22
    Description: Der Band möchte der Debatte um feministische Theorie neue Impulse geben, vor allem in der Philosophie. »Geschlecht« wird hier zwar ähnlich wie in den Naturwissenschaften noch immer weitgehend ausgeschlossen oder marginalisiert. Stellt man diesen Begriff aber ins Zentrum des Denkens, kann er neue Perspektiven auf grundlegende philosophische Probleme öffnen: auf Vernunft, Macht, Handeln, Gerechtigkeit, Demokratie. Die Texte zur politischen Theorie, Ethik, Anthropologie und Metaphilosophie, die der Band vereint, wollen in diesem Sinne das kritische Potenzial der Gender Studies für die Philosophie nutzen.
    Keywords: Gender ; Philosophie ; Queer ; Theorie ; Feminismus ; Intersektionalität ; Politikwissenschaft ; Anthropologie ; Kritische Theorie ; Diskursanalyse ; Sexuelle Differenz ; Diversity ; Geschlechterforschung ; Geschlecht ; Gender Studies ; Kulturwissenschaft ; Philosophy ; Political Science ; Critical Theory ; Cultural Studies ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFS Social groups::JFSJ Gender studies, gender groups ; bic Book Industry Communication::H Humanities::HP Philosophy
    Language: German
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The topics covered in this Special Issue range from breastfeeding and early-life nutrition to effects on microbiota, infection, allergy, asthma, and the mechanisms of immunomodulation via (the early introduction of) nutrition on infections and the development of (food) allergies.
    Keywords: diet ; pregnancy ; cord blood ; fatty acids ; n-3 PUFAs ; n-6 PUFAs ; arachidonic acid ; phospholipids ; atopic eczema ; NICE birth cohort ; multi-allergen ; early introduction ; food allergy ; safety ; efficacy ; prevention ; allergic sensitization ; foetal immune ontogeny ; gene/environment interactions ; asthma ; eczema ; maternal diet ; PUFAs ; vitamin D ; Mediterranean diet ; microbiome ; breastfeeding ; functional gastrointestinal disorder ; partial hydrolysate ; peptide ; protein ; infancy ; childhood ; immune development ; probiotic ; microbiota ; allergy ; atopic dermatitis ; breastmilk ; house dust mite ; Der p 1 ; Asthma ; total IgE ; atopy ; sensitization ; oral tolerance ; early food introduction ; milk protein ; cow’s milk allergy (CMA) ; maternal atopy ; epigenetics ; pediatric asthma ; cohort study ; immune complex ; trained immunity ; RSV ; bovine IgG ; preF protein ; cow’s milk allergy ; allergen ; hypoallergenic infant formula ; n/a ; IgA deficiency ; selenium deficiency ; zinc deficiency ; recommended dietary allowances ; immune system ; allergen molecules ; milk allergen micro-array ; peptides ; anaphylaxis ; milk tolerance ; diagnosis ; IgE sensitization ; children ; bic Book Industry Communication::M Medicine
    Language: English
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-05-09
    Description: Gerodete Wälder, Landspekulationen, Care-Krise: Kann gemeinschaftliches Eigentum helfen, die sozial-ökologische Krise zu überwinden? In den Philippinen sind vorkoloniale kollektive Landrechte Indigener rechtlich anerkannt. Wie manifestiert sich unter diesen Bedingungen die sozial-ökologische Krise? Mit feministischer Forschungsperspektive nähert sich Janina Dannenberg dieser Frage in einer Fallstudie zu Materialität und Alltagspraxis der Matigsalug Manobo in Bukidnon an. Der (Re)Produktivitätsansatz, der analytisch feministische Ökonomiekritik und Ökologische Ökonomik miteinander verbindet, wird dezidiert empirisch getestet, kritisch diskutiert und im Sinne von Bruno Latours »Nichtmoderne« erweitert.
    Keywords: Soziale Ökologie ; Nachhaltige Entwicklung ; Indigene ; (Re)Produktivität ; Landrechte ; Philippinen ; Feminismus ; Bruno Latour ; Gesellschaft ; Natur ; Geschlecht ; Nachhaltigkeit ; Humanökologie ; Umweltsoziologie ; Gender Studies ; Politikwissenschaft ; Social Ecology ; Sustainable Development ; Indigenous ; (re)productivity ; Land Rights ; Philippines ; Feminism ; Society ; Nature ; Gender ; Sustainability ; Human Ecology ; Environmental Sociology ; Political Science ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNU Sustainability ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNT Social impact of environmental issues
    Language: German
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Helicobacter pylori is one of the most common infections in the world, affecting roughly half of all humans. Although it is not an infection that causes death immediately after infection, it is one of the largest emerging infectious diseases in the history of humankind, causing a wide variety of diseases and, in the long term, serious complications such as stomach cancer. This Reprint contains empirical studies and reviews regarding the diagnosis, treatment, complications, and management of H. pylori infection, including new diagnostic methods, effective eradication regimens, the management of gastric cancer, and other topics.
    Keywords: gastric cancer ; biliopancreatic reflux ; gastritis ; carcinoma ; endoscopic surveillance ; Helicobacter pylori infection ; gastric stump cancer ; Helicobacter pylori ; H. pylori ; rifabutin ; treatment ; eradication failure ; culture ; bismuth ; rescue ; Hp-EuReg ; third-generation ultrathin endoscope ; transnasal endoscopy ; narrow-band imaging ; Kyoto classification of gastritis ; gastric atrophy and intestinal metaplasia ; diagnosis ; stool antigen test ; urea breath test ; peptic ulcer disease ; triple therapy ; vonoprazan ; dyspepsia ; Kyoto Classification of Gastritis ; cagA ; Okinawa ; endoscopic findings ; Helicobacter infection ; tetracycline ; eradication ; penicillin allergy ; furazolidone ; metronidazole ; amoxicillin ; child ; host genetic factor ; iron deficiency anemia ; iron demand ; iron uptake ; sports activity ; virulence factor ; gastric lymphoma ; MALT lymphoma ; radiotherapy ; chemotherapy ; rituximab ; dual therapy ; vonoprazan (VPZ) ; amoxicillin (AMOX) ; clarithromycin (CAM) ; bic Book Industry Communication::M Medicine
    Language: English
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  • 39
    Publication Date: 2024-02-27
    Description: Collective monograph contains the results of scientific research devoted to new views and proposals for the diagnosis of certain diseases. The proposed solutions are important for clinical practice and inspire optimism in obtaining encouraging results in overcoming some pathologies. Chapter 1 is dedicated to endoscopic retrograde cholangiopancreatography - a contrast study of the bile ducts and ductal system of the pancreas, which is achieved by their cannulation with the help of a flexible endoscope and their visualization by X-ray (fluoroscopy). Thanks to this, it becomes possible to diagnose and perform medical interventions for choledocholithiasis, benign and malignant obstruction of the bile ducts, chronic pancreatitis accompanied by obstruction of the pancreatic ducts. Chapter 2 presents the results of the development of a thermoelectric device for diagnosing inflammatory processes and pain syndrome in degenerative-dystrophic diseases of the lumbosacral spine. Such a device makes it possible to save, process and visualize measurement results on the display of the device and on a personal computer in real time. The results of clinical studies of thermometric indicators in the lumbosacral region of the spine in persons with chronic pain syndrome against the background of degenerative-dystrophic pathology of the spine in the presence of hernias and protrusions of intervertebral discs are given. The effectiveness of the proposed thermoelectric device in medical practice has been confirmed. Chapter 3 presents the results of the examination of various contingents of the population: students, athletes, mobile operators, people with hearing loss, post-covid syndrome and psychophysiological lability developed under martial law. The features of information processing by examinees with different degrees of functional mobility of nervous processes are highlighted. It was found that the deprivation of auditory function, post-conviction syndrome, psychophysiological lability developed in the conditions of martial law significantly reduce the level of neural processes and the ability to process information. The evaluation scales of neurodynamic and sensorimotor functions proposed for use in the medical field can be used to optimize diagnosis and increase the effectiveness of monitoring neurological morbidity, including in people with special needs. Chapter 4 is devoted to the problems of children's neuropsychiatric diseases, in particular brain damage in children with ASD. Restrained optimism is expressed for the prospect of overcoming this severe psychiatric pathology in the foreseeable future due to the introduction of genetic, biochemical and immunodiagnostic approaches, as well as metabolic and immunotherapeutic interventions with neuroprotective effects. Arguments are presented in favor of the fact that the successful testing in clinical practice of evidence-based personalized multidisciplinary strategies of diagnosis and treatment will allow a breakthrough in the clinical management of children with severe mental disorders in the near future. This will provide not only the possibility of recovery from a prognostically unfavorable and currently incurable neuropsychiatric disorder, but will also contribute to stopping the large-scale threatening epidemic of neuropsychiatric syndromes in the modern child population. Chapter 5 presents the evolution of views on the problem of Internet addiction, provides information on its prevalence, comorbidity with mental disorders, and provides an overview of modern clinical classifications and psychometric tools for its diagnosis. A single definition of "cyber addiction" is singled out, based on the fact that the object of addiction is interaction with various information resources and technical means. The proposed clinical diagnostic criteria, which are based on the criteria for the diagnosis of mental and behavioral disorders due to the use of psychoactive substances ICD-11, and the characteristics of the boundary with normative behavior when using various information resources and technical means are provided. The development and validation of a new psychodiagnostic screening tool based on the proposed cyber addiction paradigm, the YSCAS scale, is presented. The monograph is intended for doctors and practitioners who are engaged in the search and implementation of effective diagnostic methods to overcome the problems associated with the detection and treatment of certain pathologies. The monograph can also be useful to postgraduate and master's students of universities in the relevant educational and scientific profile.
    Description: Published
    Keywords: Endoscopic retrograde cholangiopancreatography ; Endoscopic lithoextraction ; Osteochondrosis of the spine ; Thermoelectric device ; Individual-typological properties ; Functional mobility ; Sensorimotor reactivity ; Autism spectrum disorders ; Attention deficit hyperactivity disorder ; Obsessive-compulsive syndrome ; Immunodiagnostics ; Internet addiction ; Cyberaddiction ; YSCAS scale ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint focuses on the importance of the micronutrient iron in human physiological iron homeostasis and iron-related diseases. Daily adequate dietary iron supply ensures vital body functions and hemoglobin synthesis during erythropoiesis. During the last few decades, scientific evidence has shown that the maintenance of human iron homeostasis is an important factor for physical and mental health. The present reprint gives an overview of how iron, as an essential dietary element, is responsible for physiological and pathological biochemical processes in the human body. For the readership, this relevant information will provide an evidence-based update on the complex regulatory mechanisms and related diseases of iron metabolism.
    Keywords: iron metabolism ; iron homeostasis ; micronutrient iron ; physiology ; pathology ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 41
    Publication Date: 2024-02-26
    Description: In the current scheme, the Institutions of Higher Education have the great responsibility to support academic growth and permanently guide the members of the university community in the teaching-learning process, in order to contribute to a better performance of the aspiring professionals who attend their classrooms. In recent times, respiratory system problems have been the cause of loss of life, especially since the appearance of COVID 19, which brought a pandemic of unprecedented proportions, which is why it is considered important to compile important data on this health issue. Considering that respiratory diseases are health problems that carry a high risk of impact on the quality of life of people and can cause death if they are not detected and treated in time, knowing about them and preventing them is a priority. In each area of specialty, we aim to comply with the established standards in an ethical and comprehensive manner. In the health area, the mission is to train a quality professional with an integral vision of the world, to form a man committed to the health problems that affect humanity, capable of facing critical situations of daily practice.
    Description: Published
    Description: En el esquema actual, las Instituciones de Educación Superior, tienen la gran responsabilidad de apoyar en el crecimiento académico y orientar de forma permanente en el proceso de enseñanza- aprendizaje, a los integrantes de la comunidad universitaria, con el fin de aportar para un mejor desempeño de los aspirantes a profesionales, que asisten a sus aulas. Los problemas del aparato respiratorio han sido en los últimos tiempos causa de pérdidas de vidas, en especial desde la aparición del COVID 19 que trajo una pandemia de proporciones nunca vistas, es por esa razón que se considera importante realizar una recopilación de datos importantes referentes a esta temática de salud. Considerando que las enfermedades respiratorias constituyen problemas de salud que conllevan un alto riesgo de impacto en la calidad de vida de las personas y que pueden causar la muerte de las personas sino se detectan se tratan a tiempo, conocerlas y prevenirlas es una prioridad. En cada área de especialidad, se pretende cumplir con los estándares establecidos en forma ética e integral. En el área de la salud la misión es formar un profesional de calidad, con una visión integral del mundo, formar un hombre comprometido con los problemas de salud, que afectan a la humanidad, capaz de enfrentar situaciones críticas de la práctica cotidiana.
    Keywords: Función Respiratoria ; Prevención ; Salud Pública ; Tratamiento ; bic Book Industry Communication::M Medicine
    Language: Spanish
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  • 42
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue addresses recent advances in the research of plant-derived natural products, their mechanisms of action and how they can influence health and disease. Plant-derived natural products have been well known since antiquity due to their beneficial effects on human health, and since then, they have attracted the interest of the scientific community, leading to the identification, isolation and quantification of their compounds and research on their biomedical properties. They have been found to be rich in phytochemicals, such as terpenes and phenolic compounds, with proven antioxidant, anti-inflammatory, antimicrobial, antitumor and prebiotic properties, and therefore, they have been suggested as potential candidates for the therapeutic management of several chronic diseases. Some of them include inflammatory bowel disease, diabetes, non-alcoholic fatty liver disease, arthritis and cancer, in which inflammation, oxidative stress and dysbiosis mechanisms are implicated. Furthermore, given the increased economic burden, the side effects and the low compliance rates of patients who receive standard medical treatments, plant-derived natural products could possibly serve as adjunct therapeutic agents for chronic diseases.
    Keywords: plants ; natural products ; free radicals ; inflammation ; medicinal ; caffeic acid ; antibacterial ; antifungal ; antioxidant ; anticancer ; juglone ; Juglans regia ; mogrol ; mogroside ; phytochemical ; pharmacology ; osteoporosis ; antiobesity ; anti-inflammation ; neurodegenerative disorders ; anticancer agents ; aromadendrane ; bryophytes ; cytokinesis inhibitor ; Plagiochila species ; plagiochilins ; analgesic activity ; traditional medicine ; wound healing ; colon carcinogenesis ; 1,2 dimethylhydrazine ; hesperetin ; capecitabine ; Jatropha tanjorensis ; Fraxinus micrantha ; HPTLC ; anti-obesity activity ; high-fat diet model ; histological ; Alzheimer ; acetylcholinesterase inhibitors ; Euonymus laxiflorus Champ. ; bioactive compounds ; medicinal plants ; P. lentiscus ; GC/MS ; HPLC-DAD ; antioxidant activity ; antibacterial activity ; antifungal activity ; extract ; molecular docking ; Artemisia arborescens ; Artemisia inculta ; phenolic compounds ; terpenes ; trace metals ; antioxidant capacity ; Eurycoma longifolia Jack ; anti-inflammatory ; antinociceptive effect ; antipyretic effects ; gastroprotective activity ; gastric ulcer ; Thai traditional medicine ; phytochemicals ; inflammatory bowel disease ; gut microbiota ; Mastiha ; Curcumin ; Boswellia serrata ; Artemisia absinthium ; lipidomic profile ; Tulsi ; Ocimum sanctum ; ischemic stroke ; photothrombotic ischemia ; medicinal plant ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 43
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Translational research is required to uncover the underlying pathomechanisms of neurological and psychiatric disorders, search for new biomarkers, and develop novel therapeutics. Complex polygenic, multifactorial, and heterogeneous mechanisms have been elucidated using in vivo and in vitro models. Advanced preclinical models have recently revealed an intriguing interaction between sex/gender and aging in the pathogenesis and clinical manifestations of neuropsychiatric disorders. Despite these advances, much work remains to be carried out to fully understand the underlying pathology of these conditions and to develop treatments that can significantly improve the lives of those who suffer from them. The current challenge in the field of neurological and psychiatric disorders is the development of disease-modifying, effective treatments for these complex and long-term debilitating conditions with a high malady burden. The first edition of this research topic, entitled 'Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models,' emphasizes the importance of translational research in bridging the gap between basic research and clinical applications. Furthermore, it provided a venue for researchers to share their findings and progress in translational research in this field.
    Keywords: Alzheimer&rsquo ; s disease ; Parkinson&rsquo ; multiple sclerosis ; stroke ; migraine ; pain ; depressive disorder ; anxiety disorder ; autism spectrum disorder ; sleep wake disorders ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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    Hamburger Edition | Hamburger Edition
    Publication Date: 2024-05-12
    Description: Gewalt ist ein soziales Ereignis, das alltäglich ist, auch wenn sich Regionen der Welt mitunter massiv in ihren Gewaltniveaus unterscheiden. Und doch wird Gewalt – zumindest in den westlichen Gesellschaften – als Rätsel oder exotisches Geschehnis wahrgenommen, mit Auswirkungen, die selbst noch in den Sozialwissenschaften zu beobachten sind. Denn die Gewaltforschung tut sich einigermaßen schwer, Gewalt zu erklären, wenn nicht sogar der Versuch der Erklärung dezidiert zurückgewiesen wird. Erklärungen, die jeweils bei den Motiven von Akteuren, bei situativen Interaktionsdynamiken oder gesellschaftlichen Bedingungskonstellationen ansetzen, können allein nicht überzeugen. Die Autoren schlagen vor, an prozessualen Erklärungen von Gewalt zu arbeiten, die den Blick auf die Vorgänge der Verursachung richten, um so der wissenschaftlichen Diskussion um Gewalt einen neuen methodischen Impuls zu geben.
    Keywords: Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: German
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    transcript Verlag
    Publication Date: 2024-03-29
    Description: Peru's industrial mining sector is highly conflictual and characterized by social disputes. Many of these conflicts are fought not only in politics but also in the courts, as activists attempt to hold corporate and state actors liable for human rights violations. At the same time, they face an increasing criminalization of their protests. Law is thus both an emancipatory tool for activists to access justice and an instrument for political and economic elites to prevent social change. Based on ethnographic field work, Angela Lindt sheds light on various mining disputes in Cajamarca and Piura and examines the role of law in resolving these conflicts.
    Keywords: Human Rights ; Social Movements ; Mining ; Peru ; Protest ; Law ; Transnational Corporations ; Democracy ; Politics ; Economy ; International Relations ; Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPW Political activism / Political engagement::JPWG Pressure groups, protest movements and non-violent action ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPV Political control and freedoms::JPVH Human rights, civil rights
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: undefined
    Keywords: Medicine ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
    Language: English
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  • 47
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Various classes of natural and synthetic molecules that can be classified as biomaterials find application in all fields of dentistry. Biomaterials should be biocompatible to minimise toxicity and bioactivity to ensure or simulate biological effects. They are used, for instance, to enhance antibacterial activity and improve the healing process. Calcium silicates, for illustration, are biomaterials used in endodontics that have proven their excellent biological, physico-chemical, and mechanical properties. However, some of these are considered too soluble, and this is almost completely due to their hardness when used as endodontic sealers, making endodontic retreatment very difficult. Despite manufacturers' best efforts, it is sometimes difficult to marry bioactivity, biocompatibility, and clinical benefits in a biomaterial; therefore, in this content, the work of researchers is invaluable.
    Keywords: calcium silicate cement ; retrograde materials ; premixed cement ; powder–liquid cement ; chemical composition ; EDX ; caries prevention ; anterior restorations ; ceramic ; dental veneers ; follow-up ; non-vital teeth ; porcelain laminate veneers ; vital teeth ; antimicrobial ; osseointegration ; surface modification ; tissue engineering ; root canal retreatment ; calcium silicate-based cement ; ProTaper Universal Retreatment ; D-Race ; dentin hypersensitivity ; desensitizing agents ; calcium phosphate ; hydroxyapatite ; nano-hydroxyapatite ; peri-implantitis ; periodontitis ; periapical radiograph ; deep learning ; neural networks ; image enhancement ; carious lesion activity ; irreversible pulpitis ; partial pulpotomy ; vital pulp therapy ; mineral trioxide aggregate ; furcation involvement ; image segmentation ; Gaussian high-pass filtering ; image preprocessing ; CNN ; calcium silicate material ; confocal laser scanning microscope ; deciduous tooth ; digital microscopy ; flowability ; micro-CT ; pulpectomy primary teeth ; root canal filling ; SEM ; zinc oxide eugenol ; bic Book Industry Communication::M Medicine
    Language: English
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  • 48
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The healthcare system’s ability to diagnose and care for people with schizophrenia has improved in recent decades, as effective pharmacological and psychosocial interventions are now available. However, schizophrenia remains a leading cause of disability and premature mortality. The utilization of pharmacological and psychosocial interventions in the healthcare system, which have the potential to significantly improve the quality of life for people with schizophrenia, heavily depends on medical professionals completing accurate and comprehensive assessments of patients’ psychopathologies, cognitive profiles, physical health statuses and any environmental factors that may influence them. This Special Issue reprint on schizophrenia, from the Journal of Clinical Medicine, presents a collection of articles on current approaches to assessment and treatment, as well as new findings and future perspectives of schizophrenia research and care.
    Keywords: schizophrenia ; ERP ; mismatch negativity ; MMN ; P3a ; illness duration ; real-life functioning ; motivation circuits ; negative symptoms ; RDoC ; positive valence system ; salience system ; deficit syndrome ; diagnosis ; cognitive function ; social skills training ; physical comorbidities ; childhood abuse ; internalized stigma ; neutrophil-to-lymphocyte ratio ; antipsychotics ; hypothyroidism ; inflammatory markers ; expressive deficits ; experiential deficits ; functioning ; quality of life ; first psychotic episode ; first episode ; emotional processing ; social cognition ; MCCB ; MSCEIT ; real-world studies ; real-world effectiveness ; tolerability ; treatment adherence ; second-generation antipsychotics ; long-acting injectable antipsychotics ; delusional disorders ; psychosis ; sex ; women ; psychopathology ; construct ; schizophrenia spectrum ; renaming ; rethinking ; revising ; effort expenditure ; recent-onset schizophrenia ; persistent negative symptoms ; motivation ; neuropeptide S ; cognitive functioning ; rehabilitation ; AEP ; QEEG ; switch ; extrapyramidal symptoms ; treatment ; cognitive deficits ; self-evaluation of negative symptoms ; health-related quality of life ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 49
    Publication Date: 2024-01-25
    Description: Das Bundesministerium für Wissenschaft und Klimaschutz (BMWK) möchte innovationsfreundliche Rahmenbedingungen für Reallabore schaffen. Im Sommer 2023 hat es dazu ein Grünbuch Reallabore veröffentlicht und einen Konsultationsprozess für ein Reallabore-Gesetz eingeleitet. Das Netzwerk Reallabore der Nachhaltigkeit begrüßt die Initiative, sieht aber zugleich erheblichen Gestaltungsbedarf. Die NaWis-Mitglieder unterstützen die hier vorgestellte Position des Netzwerks.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
    Type: contributiontoperiodical , doc-type:contributionToPeriodical
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  • 50
    Publication Date: 2024-01-25
    Description: Für die Landesregierung Nordrhein-Westfalen (NRW) ist die industriell genutzte Kohlenstoffabscheidung und -speicherung (engl. industrial carbon capture and storage, kurz iCCS) ein zentraler Baustein für den Übergang zu einer klimaneutralen Industrie bis 2045. Dafür braucht es aber eine breite gesellschaftliche Akzeptanz - zumal Pläne zur CO2-Abscheidung bei Kohlekraftwerken vor über zehn Jahren schon einmal an mangelnder gesellschaftlicher Akzeptanz gescheitert sind. In diesem In Brief haben die Autor*innen die Ergebnisse von zwei durchgeführten Akzeptanzstudien zu iCCS in NRW zusammengefasst und diskutieren, welche Handlungsempfehlungen sich daraus ergeben.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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    Publication Date: 2024-01-25
    Description: Nordrhein-Westfalen (NRW) ist Heimat energieintensiver Industrien wie der Stahl- und Chemieindustrie. Künftig wird grüner Wasserstoff notwendig sein, damit die Industrie in NRW Klimaneutralität erreichen kann. Die Herausforderungen hierbei sind jedoch vielfältig - auch wenn die Akzeptanz für grünen Wasserstoff sowohl in der Gesellschaft als auch bei unmittelbar beteiligten Akteursgruppen hoch ist. Die Autor*innen fassen in diesem In Brief die Ergebnisse von zwei durchgeführten Akzeptanzstudien zu grünem Wasserstoff in NRW zusammen und diskutieren, welche Handlungsempfehlungen sich daraus ergeben.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 52
    Publication Date: 2024-03-20
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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    Publication Date: 2024-03-20
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 54
    Publication Date: 2024-03-20
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 55
    Publication Date: 2024-03-20
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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    Weinheim : Beltz
    Publication Date: 2024-03-20
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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    Publication Date: 2024-03-20
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 58
    Publication Date: 2024-03-20
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 59
    Publication Date: 2024-03-20
    Description: Dieses Buch bietet einen Leitfaden für mehr Klimaschutz an Schulen und holt Schulleitungen, Lehrkräfte und Schüler:innen gemeinschaftlich ins Boot - denn Klimaschutz ist eine Gemeinschaftsaufgabe. Mit dem "Whole School Approach" wird die ganzheitliche Umsetzung von Klimaschutzaktivitäten in der Schulentwicklung angestoßen und auf schulischer Ebene ermöglicht und erleichtert. Ziel ist es, Lehrer:innen in ihrer Gestaltungskompetenz für mehr Klimaschutz zu stärken - dies geschieht durch konkrete Vorschläge für die Arbeit mit Schüler:innen im Unterricht. Partizipative Methoden der Beteiligung sollen die Schüler:innen empowern und den Lehrkräften Ideen geben, um die eigene Selbstwirksamkeit, aber auch die der Schüler:innen zu steigern. Die zentrale Kernbotschaft lautet: ein Klimaschutzprojekt an der Schule ist wesentlich für die strukturelle Verankerung von Bildung für nachhaltige Entwicklung im Schulalltag. Der Leitfaden gibt Anregungen für die Unterrichtsgestaltung, Anregungen für die Entwicklung eines Klimaschutzleitbildes, Hinweise für das Gebäudemanagement und Ideen zur Einbindung des schulischen Umfelds.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 60
    Publication Date: 2024-03-20
    Description: Angesichts von Extremwetterereignissen, Klimaprognosen und Bewegungen wie Fridays for Future lässt sich schwer leugnen, dass ein Teil der Menschheit auf eine Weise lebt, die eine gut bewohnbare Welt höchst unwahrscheinlich macht. Städten wird in dieser Situation eine zentrale Rolle zugeschrieben. Sie können die Welt vor der Erderwärmung retten - oder sie sind die Ersten, die untergehen. Doch was genau wird getan, um Städte in Richtung Nachhaltigkeit zu transformieren? Britta Acksel nimmt Aktionspläne, Klimafestivals, Awards und weitere Transformationsinstrumente in den Blick. Ethnographisch fundiert zeigt sie auf, wie sich die Arbeit mit dieser speziellen Form von Policy-Werkzeugen gestaltet - und welche Bemühungen besonders aussichtsreich erscheinen.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
    Type: doctoralthesis , doc-type:doctoralThesis
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  • 61
    Publication Date: 2024-03-21
    Description: Ways of evaluating the societal impact of real-world labs as a transdisciplinary and transformative research format are under discussion. We present an evaluation approach rooted in structuration theory, with a focus on structure-agency dynamics at the science-society interface. We applied the theory with its four modalities (interpretation schemes, norms, allocative and authoritative resources) to the case of the Mirke neighbourhood in Wuppertal, Germany. Six projects promoted the capacity for co-productive city-making. The effects of the projects were jointly analysed in a co-evaluation process. Previously proposed subcategories of the modalities as an empirical operationalisation were tested and confirmed as being applicable. Five new subcategories were generated. The use of the modalities seems appropriate for co-evaluation processes. The tool is practical, focused on real-world effects, and suitable for transdisciplinary interpretation processes. We encourage further empirical testing of the tool, as well as development of the subcategories.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: English
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  • 62
    Publication Date: 2024-03-21
    Description: Real-world laboratories (RwLs) are gaining further traction as a means to achieve systemic impacts towards sustainability transformation. To guide the analysis of intended impacts, we introduce the concept of leverage points, discerning where, how, and to what end RwLs intervene in systems. Building on conceptual reasoning, we further develop our argument by exploring two RwL cases. Examining RwLs through the lens of the leverage points opens the way for a balanced and comprehensive approach to systemic experimentation. We invite RwL researchers and practitioners to further advance RwLs' transformative capacity by targeting the design and emerging direction of a system, contributing to a culture of sustainability.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
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  • 63
    Publication Date: 2024-04-10
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
    Type: contributiontoperiodical , doc-type:contributionToPeriodical
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  • 64
    Publication Date: 2024-04-11
    Description: The co-operation between municipalities and civil society actors and their independent impulses for urban development are discussed under the terms of co-production and city-making. This article summarises these activities as co-productive city-making (koSM). Forms of as well as advantages and disadvantages of koSM have been discussed in research and practice so far, but analyses of the longitudinal genesis of these activities and their significance for the development of a specific area are rare. This article uses the longitudinally collected, mixed-method data of a constellation analysis of the development of the Mirke neighbourhood in Wuppertal/Germany. Based on four points in time, the dynamics as well as the spatial development of the koSM can be presented - individually and in comparison to other developments. It can be seen that the koSM in the Mirke has grown at an above-average and dynamic rate and can accordingly be interpreted as a motor of neighbourhood development. Main actors and locations are identified. The study is the basis for a follow-up work analysing the reasons and structural effects of the koSM. The koSM is discussed both in its interrelations with municipal action and in its significance for integrated and sustainable urban development. The method of constellation analysis is critically discussed with regard to the relationship between effort and benefit.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 65
    Publication Date: 2024-04-22
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 66
    Publication Date: 2024-04-22
    Description: Real-world labs are witnessing continued growth and institutionalization in the field of transformation-oriented sustainability research, as well as in adjacent disciplines. With their experimental research agendas, these labs aim at sustainability transformations, however, there is still a need to improve the understanding of their impacts. Drawing from this Special Issue's contributions, we offer a broad overview of the impacts achieved by various real-world labs, highlight the diverse areas and forms of impact, and elucidate strategies as well as mechanisms for achieving impact. We present methodological advances, and address common challenges along with potential solutions for understanding and realizing impact.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: English
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  • 67
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    Publication Date: 2024-02-23
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 68
    Publication Date: 2024-05-13
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 69
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    Marburg : Metropolis-Verlag
    Publication Date: 2024-05-13
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 70
    Publication Date: 2024-05-13
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 71
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    Marburg : Metropolis-Verlag
    Publication Date: 2024-05-13
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: German
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  • 72
    Publication Date: 2024-05-13
    Description: In Germany, there are over 32,000 schools, representing great potential for climate protection. On the one hand, this applies to educational work, as understanding the effects of climate change and measures to reduce GHG emissions is an important step to empower students with knowledge and skills. On the other hand, school buildings are often in bad condition, energy is wasted, and the possibilities for using renewable energies are hardly used. In our "Schools4Future" project, we enabled students and teachers to draw up their own CO2 balances, identify weaknesses in the building, detect wasted electricity, and determine the potential for using renewable energies. Emissions from the school cafeteria, school trips, and paper consumption could also be identified. The fact that the data can be collected by the students themselves provides increased awareness of the contribution made to the climate balance by the various school areas. The most climate-friendly school emits 297 kg whilst the school with the highest emissions emits over one ton CO2 per student and year. Our approach is suitable to qualify students in the sense of citizen science, carry out a scientific investigation, experience self-efficacy through one's own actions, and engage politically regarding their concerns.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
    Language: English
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  • 73
    Publication Date: 2024-05-31
    Description: The sustainable transformation of society is one of the greatest challenges of our time. Universities are central actors for knowledge generation and transfer in the sustainability field and, at the same time, are facing the question of how they can become sustainable social actors and make their activities and infrastructure sustainable. Against this background, the 16 member universities of the State Rectors' Conference of North Rhine-Westphalia have joined forces in the Humboldtn initiative to pool their efforts in the field of sustainability and to anchor generational responsibility for sustainable action in research, teaching, administration, infrastructure, and transfer. How the joint responsibility for the questions for the future in the aforementioned complex of topics is addressed via Humboldtn and which focal points are set in the process will be presented and discussed using examples from the institutional sustainability transformation and examples from the research area from RWTH Aachen University. In this way, the implementation of transformation processes at universities and their possible blueprint effect can be illuminated.
    Keywords: ddc:300
    Repository Name: Wuppertal Institut für Klima, Umwelt, Energie
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  • 74
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    transcript Verlag
    Publication Date: 2024-03-29
    Description: Wie steht es um den Staat im »digitalen Zeitalter«? Der Wandel des Staates in der Leistungsdimension und der Staatlichkeit in der Steuerungsdimension ist eher die Regel als eine Ausnahme. Für die 1990er-Jahre wurde er mit dem Modellwechsel vom »intervenierenden Leistungsstaat« zum »kooperativen Gewährleistungsstaat« als Transformation beschrieben. Im Angesicht der »Digitalisierung« und weiterer Megatrends zeigen sich die nächsten tiefgreifenden Wandlungsprozesse. Samuel Greef beleuchtet den neuen Mix aus Steuerungsformen und -instrumenten sowie eine hybridere Leistungserbringung, welche die Gestalt des Staates in unterschiedlichen Politikfeldern prägen. Sein Fazit: Deutschland befindet sich heute auf dem Weg zum »kontingenten Patchworkstaat«.
    Keywords: Staat ; Staatlichkeit ; Steuerung ; Governance ; Digitalisierung ; Deutschland ; Politik ; Internet ; Politische Theorie ; Policy ; Digitale Medien ; Politikwissenschaft ; State ; Control System ; Digitalization ; Germany ; Politics ; Political Theory ; Digital Media ; Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPH Political structure and processes::JPHC Constitution: government and the state ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPQ Central / national / federal government::JPQB Central / national / federal government policies
    Language: German
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  • 75
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    Amsterdam University Press
    Publication Date: 2024-03-29
    Description: The Netherlands played a remarkable role during the October War and the oil crisis of 1973. In secret, the Dutch government sent a substantial amount of ammunition and spare parts to Israel. The Dutch supported Israel also politically. Within the EC they vetoed a more pro-Arab policy. The Arab oil producing countries punished The Netherlands by imposing an oil embargo. The embargo against the Netherlands was intimidating. The Netherlands was dependent on Arab oil. The embargo seemed to threaten the Dutch position in the international oil sector. The government introduced several measures to reduce oil consumption. However, within two months it became clear that oil continued to arrive in Rotterdam. There was in fact no oil shortage in the Netherlands. The Netherlands even profited from the oil crisis. The energy situation in The Netherlands was much better than in other West European countries. The Dutch, therefore, rejected French plans for a more interventionist energy policy. Atlanticism and liberalism were the key words of the Dutch policy during the oil crisis. This book is the result of intensive research in all relevant Dutch archives. The authors had free access to all the files they wanted to see. They also used resources from other countries involved. Many politicians were interviewed. The result is a surprising analysis of the oil crisis of 1973, and of the Dutch role in particular. This title is available in the OAPEN Library - http://www.oapen.org.
    Keywords: Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPB Comparative politics
    Language: English
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  • 76
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    transcript Verlag | transcript Verlag
    Publication Date: 2024-04-03
    Description: Der »Sommer der Migration« 2015 transformierte die europäische Migrationspolitik. Judith Kopp analysiert anhand des Fluchtursachen-Diskurses, wie gesellschaftliche Akteur*innen strategisch darum ringen, ihre Interessen durchzusetzen. Dazu zeichnet sie die Herausbildung des hegemonialen Verständnisses von Fluchtursachenbekämpfung kritisch nach. Dieses schreibt sich in die Reorganisation des EU-Grenzregimes nach 2015 ein. Gleichzeitig verweisen die diskursiven Kämpfe auf eine stärkere Sichtbarkeit von Geflüchteten vor dem Hintergrund globaler Nord-Süd-Verhältnisse.
    Keywords: Europa ; Migration ; Entwicklung ; Hegemonie ; Flucht ; Fluchtursache ; Diskurs ; Grenze ; Politik ; Migrationspolitik ; Politische Theorie ; Europäische Politik ; Flüchtlingsforschung ; Politikwissenschaft ; Europe ; Development ; Hegemony ; Fleeing ; Cause of Refugee ; Discourse ; Border ; Politics ; Migration Policy ; Political Theory ; European Politics ; Refugee Studies ; Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPQ Central / national / federal government::JPQB Central / national / federal government policies ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSN International institutions ; thema EDItEUR::1 Place qualifiers::1Q Other geographical groupings: Oceans and seas, historical, political etc::1QF Political, socio-economic, cultural and strategic groupings::1QFE EU (European Union)
    Language: German
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  • 77
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    CLACSO
    Publication Date: 2024-03-29
    Description: It is used to say that the first victim of a war is the truth. In fact, in a war in the strict sense or in a political war, the murder of the truth and the concealment of the facts occur profusely. It is not different in Brazil. Democracy was neither the first nor the only victim of the parliamentary coup (a.k.a. impeachment) in 2016. It was also the truth. Before the coup, and to justify it, anti-people and anti-national forces broadcasted, to exhaustion, a series of lies about the governments of the Workers Party (PT). The presentation of Dilma Rousseff
    Keywords: Political Science ; History ; Latin American Studies ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPH Political structure and processes::JPHV Political structures: democracy ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 78
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Advancements in digital technologies are reshaping the world of dentistry, from prosthodontics to implant dentistry. Intraoral scanners, facial scanners, 3D printers, and milling machines have revolutionized the clinical approach and operative workflow in daily practice. However, digital dentistry brings several challenges to clinicians due to the rapid evolution of new technologies and the lack of evidence-based guidelines for their correct use. The aim of this Special Issue is to cover the latest advances in the development and application of digital technologies in prosthetic and implant dentistry. We wish to provide both clinicians and researchers with a comprehensive and up-to-date source of information on current trends, limitations, and potential future applications of digital technologies in daily clinical practice.
    Keywords: dental implants ; digital impression ; intraoral scanner ; CAD/CAM materials ; toothbrushing wear ; surface ; roughness ; surface integrity ; alveolar remodeling ; tooth extraction ; intraoral digital scanning ; imaging superimposition ; less traumatic surgery ; socket healing ; implantology ; computer-aided surgery ; image-guided surgery ; zygomatic implants ; navigation system ; dental implant ; bone level ; prospective study ; sub-crestal placement ; emergence profile ; guided surgery ; digital workflow ; stereolithographic surgical guide ; accuracy ; CAD–CAM ; DICOM–STL ; static guided surgery ; clinical study ; intraoral scanners ; digital dentistry ; impression techniques ; full-arch impression ; elderly population ; dimensional measurement accuracy ; implant scan ; operator ; precision ; scan area ; trueness ; occlusion ; overloading ; complications ; implant-supported restorations ; marginal bone loss ; oral implantology ; intraoral scan ; cone-beam computed tomography ; oral surgery ; emergence angle ; retrospective study ; bic Book Industry Communication::M Medicine
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  • 79
    Publication Date: 2024-04-02
    Description: The Department of Defense (DoD) has developed new sensor technologies to support U.S. forces in Iraq and Afghanistan; these technologies are potentially useful for counterdrug operations along the southern U.S. border, but there are legal questions regarding how they may be used and how sensor information may be shared between federal agencies in domestic operations. This report examines federal law and DoD policy to answer these questions.
    Keywords: History ; Technology ; Political Science ; thema EDItEUR::N History and Archaeology::NH History::NHH African history ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSD Diplomacy ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services::JKSW Emergency services::JKSW1 Police and security services ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
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  • 80
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Nearly 18 months later, COVID-19, caused by SARS-CoV-2, continues to present significant challenges to health systems, public health, and the economy of countries across both hemispheres. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed hospitals and clinics in many countries and continue to do so. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This Special Issue collection follows on from the Special Issue “COVID-19: Current Challenges and Future Perspectives” and provides an avenue for authors from various disciplines to provide feedback on the response to and our future global preparedness for COVID-19, as well as to disseminate critical information about SARS-CoV-2 and the associated COVID-19 pandemic.
    Keywords: COVID-19 ; new-onset DM ; severe infection ; mortality ; outbreak ; P.1 variant ; Gamma variant ; SARS-CoV-2 infection ; whole-genome sequencing ; pandemic ; overweight ; obesity ; Peru ; psychological impacts ; public health ; preparedness ; mRNA-1273 ; BNT162b2 ; TAK-919 ; SARS-CoV-2 ; post-vaccination ; healthcare personnel ; vaccination ; asymptomatic infection ; HIV ; infectious disease ; excess mortality ; regdanvimab ; remdesivir ; severe ; community transmission ; population density gradient ; Dhaka ; Bangladesh ; dengue ; undifferentiated febrile illness ; antigen testing ; variants ; reinfections ; breakthrough infections ; vaccine hesitancy ; sub-Saharan Africa ; pulmonary fibrosis ; postacute COVID-19 syndrome ; tuberculosis ; helminth coinfection ; coronavirus ; coordination ; health operations and technical expertise ; AFRO ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; liver transplantation ; reproduction rate ; phylogenetic analysis ; clade GK ; D614G ; P681R ; cross-reactivity ; haemorrhage ; thrombocytopenia ; thrombosis ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) ; molecular diagnostics ; real-time polymerase chain reaction (RT-qPCR) ; economy ; income levels ; waves ; policy ; turning points ; occupational exposure ; risk factors ; personal protective equipment ; SIR model ; socio-behavioral aspects ; interaction distance ; school reopening strategy ; self-medication ; over-the-counter ; medicine use ; Pakistan ; clinical features ; Luanda ; Angola ; socioeconomic status ; risk perception ; risk prevention practices ; qualitative ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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  • 81
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    RAND Corporation
    Publication Date: 2024-03-29
    Description: U.S.-Turkish relations, long a vital element of U.S. policy, have seriously deteriorated in recent years. However, the arrival of a new U.S. administration offers an opportunity to repair recent fissures. Priority should be given to harmonizing policy toward Iraq and the Middle East as well as Central Asia and the Caucasus.
    Keywords: Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RND Environmental policy and protocols
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  • 82
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 83
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    University of Hawai'i Press
    Publication Date: 2023-10-05
    Description: Farmers in the Forest, while using examples chiefly from northern Thailand, is concerned with complex problems found in all tropical countries. In these areas rapid population growth, increasing demands for food, and burgeoning international markets for forest products and other raw materials are associated with active competition for land and natural resources in upland areas. This book brings together studies by administrators, agronomists, anthropologists, forest ecologists, geographers and jurists, who describe a variety of swidden systems and their effect on soil, forest, society, and economy. They point to conflicts between traditional farming systems and modern legal and administrative constraints now being imposed, and they describe special and technological conditions that contribute to a marginal, stagnant upland economy, increasing socio-economic disparities with the lowlands, and the serious ecological consequences of these conditions. Several possible solutions are suggested to solve these problems.
    Keywords: Sociology ; Anthropology ; Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPQ Central government::JPQB Central government policies ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHM Anthropology ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
    Language: English
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  • 84
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    Amsterdam University Press
    Publication Date: 2024-03-29
    Description: A Continent Moving West? argues that the conceptualization of migration as a one-way or long-term process is becoming increasingly wide of the mark. Rather, east-west labor migration in Europe, in common perhaps with other flows in and from other parts of the world, is diverse, fluid, and influenced by the dynamics of local and sector-specific labor markets and migration-related political regulations. The papers in this book contribute to critical understanding of the east-west migration within the European Union after the 2004 enlargement, from the new to the old member states.
    Keywords: Sociology ; Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: English
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  • 85
    Publication Date: 2024-03-29
    Description: As recent events in Iraq demonstrate, countries that have suffered civil war or rule by military regime can face a long, difficult transition to peaceful democracy. Drawing on the experiences of Bosnia, Haiti, Rwanda and Afghanistan, this outstanding volume demonstrates that newly emerging democracies need more than emergency economic support: restoring the rule of law can involve the training of a new police force, for example, or the creation of an international war crimes tribunal. Concluding with specific recommendations for the UN and EU members,Voorhoeve reminds us that disregard for human rights or delay in civilian reconciliation can lead to resurgences of violence. This title is available in the OAPEN Library - http://www.oapen.org.
    Keywords: Sociology ; Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPB Comparative politics ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology
    Language: English
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  • 86
    Publication Date: 2023-10-05
    Description: This book examines the Army's role in the war on terrorism; the Army's homeland security needs; the implications of increased emphasis on Asia; the Army's role in coalition operations; the unfinished business of jointness-the lessons learned from operations and how to prepare for the future; the Army's deployability, logistical, and personnel challenges; and whether the Army can afford its Transformation. These examinations are bracketed by an introduction, a description of the Army's place in the new national security strategy, and a summary of the authors' conclusions.
    Keywords: Political Science ; Management & Organizational Behavior ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence
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  • 87
    Publication Date: 2024-03-29
    Description: Las metodologías participativas de investigación y acción social - IAP con su fuerte propuesta epistemológica de investigar para la acción, y para y con sus actores sociales protagonistas- suman en este libro, en tiempos de su expansión, otro grano de arena con esta iniciativa. La obra refleja bien esa multiplicación y proliferación de su utilización, y a la vez pone sobre la mesa una vez más, también amenazas, límites y contradicciones de lo que se intenta hacer desde lo participativo. Los lectores podrán sondear el grado de los desfases, las continuidades y discontinuidades, las dicciones y contradicciones, los valores y ambivalencias, las emergencias de explicaciones que como obra heterogénea respecto a sus autores, localización de experiencias y procedencias, posicionamientos, y uso de las metodologías y técnicas participativas, el libro encierra en di.logo y disputa.
    Keywords: Political Science ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPH Political structure and processes::JPHV Political structures: democracy
    Language: Spanish
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  • 88
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    Duncker & Humblot
    Publication Date: 2024-03-29
    Description: Description not available.
    Keywords: Public Policy & Administration ; Political Science ; bic Book Industry Communication::J Society & social sciences::JK Social services & welfare, criminology::JKS Social welfare & social services ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCP Political economy ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCP Political economy
    Language: German
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  • 89
    Publication Date: 2024-04-02
    Description: California’s Juvenile Justice Crime Prevention Act provides funds for counties to offer evidence-based programs for high-need juvenile probationers and at-risk youth. This report, based on the annual report to the state legislature, outlines the program’s success for six outcome measures (completion of probation, restitution, and community service; arrests; probation violations; and incarcerations) and county-required supplemental outcomes.
    Keywords: Law ; History ; Political Science ; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::L Law::LN Laws of specific jurisdictions and specific areas of law::LNF Criminal law: procedure and offences::LNFQ Juvenile criminal law ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services::JKSW Emergency services::JKSW1 Police and security services ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKV Crime and criminology
    Language: English
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  • 90
    Publication Date: 2024-04-02
    Description: Drawing from 140 recently declassified documents, this report comprehensively examines the organization, territorial designs, management, personnel policies, and finances of the Islamic State of Iraq (ISI) and al-Qa‘ida in Iraq. Analysis of the Islamic State predecessor groups is more than a historical recounting. It provides significant understanding of how ISI evolved into the present-day Islamic State and how to combat the group.
    Keywords: Political Science ; History ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPW Political activism / Political engagement::JPWL Terrorism, armed struggle
    Language: English
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  • 91
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    RAND Corporation
    Publication Date: 2024-03-29
    Description: On September 11, 2001, the United States was without a plan for military operations in Afghanistan. One was quickly created by the Defense Department and operations began October 7. The Taliban was toppled in less than two months. This report describes preparations at CENTCOM and elsewhere, Army operations and support activities, building a coalition, and civil-military operations in Afghanistan from October 2001 through June 2002.
    Keywords: History ; Political Science ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
    Language: English
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  • 92
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective treatment of cancer remains a great challenge. Novel therapeutic strategies with superior anticancer ability urgently need to be discovered. In recent years, nano-drug delivery systems have been extensively investigated and applied as alternatives to conventional cancer treatments. Cancer nanomedicines aim to achieve the targeted delivery of chemotherapeutic drugs to the tumor site, utilizing strategies such as passive targeting, active targeting and stimuli-triggered drug release, while simultaneously decreasing drug accumulation in normal tissues, which together lead to improved therapeutic efficacy and reduced side effects. Currently, several cancer nanomedicines are in regular use, and several others are in various stages of development.This Special Issue will highlight recent progress in the development of novel nanomedicines and targeted drug delivery systems for cancer therapy.
    Keywords: graphene quantum dot ; targeted drug delivery ; photothermal therapy ; chemo-therapy ; polymeric prodrug ; theranostic nanocomplex ; pH-triggering releasing ; magnetic targeting ; magnetic hyperthermia ; magnetic resonance imaging ; docetaxel ; adenosine receptors ; PLGA ; nanoparticles ; lung cancer ; Notch signaling ; RBPJ protein ; drug repurposing ; fidaxomicin ; acarbose ; schaftoside ; breast cancer ; experimental skin cancer ; entrapment efficacy ; ethosomes ; metformin ; in vitro permeation ; zeta potential ; sesamol ; albumin nanoparticles ; doxorubicin ; oxidative stress ; antioxidants ; tumor-derived membrane vesicles ; cancer therapy ; tumor vaccine ; personalized immunotherapy ; low-density lipoprotein ; nanoparticle ; tumor microenvironment-responsive ; magnetic nanofluid ; improved magnetic resonance imaging ; neutral-responsive Fenton reaction ; enhanced chemodynamic therapy ; brain targeting ; folate receptor ; glioma cancer ; erlotinib ; blood–brain barrier ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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  • 93
    Publication Date: 2024-03-29
    Description: La presente antología contiene un amplio conjunto de textos que Fernando Martínez Heredia elaboró en función de los problemas sociales y retos que la práctica política socialista latinoamericana demandó al pensamiento con el objetivo de ir más allá de lo posible. Materiales vivos que nos incitan a pensar en tiempo de revolución para que, según dijera un humilde habanero que entregó su vida a esa empresa, los sueños de hoy se conviertan en la ley del mañana.
    Keywords: Political Science ; History ; Latin American Studies ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPF Political ideologies and movements::JPFC Far-left political ideologies and movements ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTQ Colonialism and imperialism
    Language: Spanish
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  • 94
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    Institut français d’études andines
    Publication Date: 2024-04-02
    Description: El espejismo del mestizaje estudia la tensión irresuelta que genera el pensamiento que se ubica en la línea divisoria entre la modernidad, identificada con el desarrollo europeo, y la colonialidad, término con el que se revelan y denuncian los excesos y las limitaciones de la modernidad. Por ello, El espejismo del mestizaje afirma que no hay modernidad sin colonialidad, siendo esta última no sólo constitutiva de la primera, sino el lugar de enunciación que revela sus miserias y sus limitaciones. Este libro está sostenido por investigaciones que, al ser todavía poco conocidas por la academia angloparlante, constituyen, sin embargo, una novedosa perspectiva para repensar Latinoamérica. Aún más, El espejismo del mestizaje, que cuestiona la universalidad de las ciencias sociales y humanas, interviene decisivamente en la discursividad propia de las ciencias modernas, y, así configura otro espacio de producción de conocimientos que, de acuerdo con Walter Mignolo, es la construcción de un “paradigma otro”, una forma distinta de pensamiento que se atreve a ver el mundo “de otro modo”.
    Keywords: arte ; Bolivia ; cultura ; mestizaje ; política ; siglo XX ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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  • 95
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    University of New Orleans Press
    Publication Date: 2024-04-02
    Description: This volume celebrates the study of Austria in the twentieth century by historians, political scientists and social scientists produced in the previous twenty-four volumes of Contemporary Austrian Studies. One contributor from each of the previous volumes has been asked to update the state of scholarship in the field addressed in the respective volume. The title Austrian Studies Today, then, attempts to reflect the state of the art of historical and social science related studies of Austria over the past century, without claiming to be comprehensive. The volume thus covers many important themes of Austrian contemporary history and politics since the collapse of the Habsburg Monarchy in 1918―from World War I and its legacies, to the rise of authoritarian regimes in the 1930s and 1940s, to the reconstruction of republican Austria after World War II, the years of Grand Coalition governments and the Kreisky era, all the way to Austria joining the European Union in 1995 and its impact on Austria's international status and domestic politics.
    Keywords: History ; Political Science ; European Studies ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: English
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  • 96
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: In this reprint, state-of-the-art research and review articles on emerging material systems for additive manufacturing (AM) are collected, with a focus on the process–structure–properties relationships. Additive manufacturing (AM) has grown and evolved rapidly in recent years. There are many exciting research and translational works in many areas of application, such as biomedical, aerospace and electronics. These advancements are typically coupled with materials development, which has resulted in more functionalities added to 3D-printed parts, such as multi-material fabrications and integration with machine learning or digital twins. Such enhancements in functionalities have enabled the evolution of AM from a rapid prototyping tool to an actual manufacturing solution. In this reprint, two reviews and thirteen original research articles are included to highlight the latest development in the field of materials science for AM.
    Keywords: titanium scaffolds ; 3D printing ; pore design ; selective laser melting ; lattice structures ; torsion ; design ; additive manufacturing ; functionally gradient lattice ; torsional stiffness ; energy absorption ; failure behavior ; ferritic steel ; heat treatment ; SLM ; nuclear application ; laser powder bed fusion ; solidification crack ; hot crack ; aluminum alloy powder ; EN AW-5083 ; AA5083 ; AlSi10Mg ; powder bed fusion ; metal matrix composites ; laser powder-bed fusion ; aluminum alloys ; reinforcement ; ceramic particulates ; grain refinement ; crystallographic texture ; mechanical properties ; laser-directed energy deposition ; melt pool ; process maps ; multi-fidelity Gaussian process ; Bayesian Optimization ; uncertainty quantification ; K418 alloy ; orientation ; phase ; microhardness ; color 3D printing ; penetration depth ; chromaticity ; image-based metric ; color reproduction ; Ti-24Nb-4Zr-8Sn ; titanium alloy ; biomedical engineering ; microstructure ; X-ray diffraction ; directed energy deposition ; shape-memory alloys ; joining of metals ; elemental powders ; 3D concrete printing (3DCP) ; hybrids ; geopolymer ; frost resistance ; UV radiation ; thermal conductivity ; surface finishing ; physical vapor deposition ; composites ; recycling ; polymer-matrix composites (PMCs) ; direct ink writing ; liquid deposition modeling ; glass fibers ; stainless steel ; AISI 316L ; AISI 630 (17-4PH) ; AISI 420 ; AISI 440C ; carbon content ; online monitoring ; electron beam melting ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 97
    Publication Date: 2023-10-05
    Description: In the face of Islam's own internal struggles, it is not easy to see who we should support and how. This report provides detailed descriptions of subgroups, their stands on various issues, and what those stands may mean for the West. Since the outcomes can matter greatly to international community, that community might wish to influence them by providing support to appropriate actors. The author recommends a mixed approach of providing specific types of support to those who can influence the outcomes in desirable ways.
    Keywords: Political Science ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPS International relations ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPW Political activism::JPWL Terrorism, armed struggle
    Language: English
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Personalized medicine for Parkinson’s disease is a growing and emerging concept in light of recent recognition that Parkinson’s is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven “one size fits all” management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital “checklists” to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
    Keywords: Parkinson’s disease ; movement disorders ; periodontitis ; periodontal disease ; hematologic tests ; Vitamin D ; oral health ; Parkinson’s Disease ; cognition ; GABAergic signaling ; cerebellum ; MRS ; response inhibition ; non-motor symptoms ; carer stress ; older persons with Parkinson’s disease ; education ; lifestyle behaviours ; diet ; cross-sectional ; population study ; neurological disorders ; precision medicine ; genetics ; clinical trials ; Parkinson’s disease (PD) ; cognitive rehabilitation ; intervention ; deep brain stimulation ; levodopa-carbidopa intestinal gel ; apomorphine ; radiofrequency ; focused ultrasound ; induced pluripotent stem cells ; cell therapy ; gene therapy ; personalized medicine ; advanced Parkinson’s disease (APD) ; apomorphine subcutaneous infusion therapy ; pain ; intrajejunal ; levodopa ; motor and non-motor symptoms ; PKG (KinetiGrap) ; rehabilitation ; device-aided therapies ; personalised medicine ; Alzheimer’s disease ; clinical trial ; impulsive-compulsive disorders (ICD) ; dopaminergic therapy ; genetic markers ; pharmacogenetic ; polymorphisms ; insomnia ; sleep quality ; assessment ; young onset Parkinson’s (YOPD) ; Emiratis ; expatriate ; genetic ; epigenetics ; societal impact ; device aided therapies ; quality of life ; non motor symptoms ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
    Language: English
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  • 99
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In the urological sphere, the number of tumor malignancies caused by cancer is continuously growing in Western countries. Although this is mainly due to the contemporary increase in the life expectancy of people in these geographic areas, many other factors are also contributing to this growth. Urological cancer is a complex and varied disease which affects different organs and mainly affects the male population. In fact, in most statistics, kidney, prostate, and bladder cancer are regularly included in the top-ten list of the most frequent neoplasms in males. The female population, however, has also been increasingly affected by renal and bladder cancer in the last decade. From these facts, it is clear that urological cancer is a problem of major concern in developed societies. This Topic Issue of Cancers intends to shed some light on the complexity of this field and will consider all useful and appropriate contributions from scientists and clinicians in order to improve urological cancer knowledge for patients’ benefit.
    Keywords: high-risk prostate cancer ; androgen receptor axis ; castration resistance ; neuroendocrine carcinoma ; PARP inhibition ; immunotherapy ; cancer genome ; precision targeting ; robot-assisted partial nephrectomy ; renal cell carcinoma ; indocyanine green ; nephron sparing ; prostate cancer survivors ; follow-up care ; primary health care ; general practice ; process evaluation ; Consolidated Framework for Implementation Research ; prostate-specific membrane antigen positron-emission tomography ; multiparametric magnetic-resonance imaging ; primary diagnosis ; prostate cancer ; systematic review ; diagnosis ; PSMA ; PSA ; tumor ; PET scan ; bladder cancer ; bisphenol A ; bisphenol S ; energy metabolism ; migration ; proliferation ; carbon-ion radiotherapy ; elderly patients ; radiotherapy ; particle beam therapy ; life expectancy ; systemic immune-inflammation index ; Charlson comorbidity index ; CAPRA-S ; early survival ; male incontinence ; robotic prostatectomy ; clear cell renal cell carcinoma ; ferroptosis ; prognostic model ; TCGA ; E-MTAB-1980 ; GLS2 ; pazopanib ; real-world data ; non-interventional study ; time on drug ; nivolumab ; everolimus ; trial-eligibility ; ureteral neoplasms ; urinary bladder neoplasms ; ureteroscopy ; CNTF ; CNTFRα ; LNCaP ; 22Rv1 ; castration resistant ; castration sensitive ; STAT3 ; ERK ; MMP ; biomarker ; Gleason grade ; transforming growth factor-β family ; activin ; INHBA ; INHBB ; INHBC ; prostate-specific antigen ; false-positive results ; real world-data ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 100
    Publication Date: 2024-03-29
    Description: Freedom of movement (FoM) is the actual or perceived degree to which individuals or groups can move from place to place within a given environment or into and out of that environment. Focusing specifically on Afghanistan, this examination considers actual and perceived FoM for a range of groups and profiles the factors that influence them and affect data reporting in potentially misleading ways.
    Keywords: Political Science ; History ; Technology ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSH Espionage and secret services ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
    Language: English
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