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  • Wiley  (11,338)
  • Oxford University Press  (4,416)
  • Nature Publishing Company
  • 1985-1989  (16,077)
  • 1945-1949
  • 1986  (16,077)
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  • 1985-1989  (16,077)
  • 1945-1949
Year
  • 1
    Electronic Resource
    Electronic Resource
    Biotech IPO Window Closing as Stocks Falter (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 759-759 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—The fabled “window” that allows biotech companies to go public is about to close, closing fast, or has already slammed shut, depending on which analyst is trying to peek through it. With Quidel (La Jolla, CA) reportedly cancelling its initial public offering (IPO), and ...
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    URL: http://dx.doi.org/10.1038/nbt0986-759a
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  • 2
    Electronic Resource
    Electronic Resource
    ‘Farmers Can't Succeed Without Agbiotech’ (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 759-759 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—“Non-commodity products” are the answer to the U.S. farmer's dilemma in the 1980s and 1990s. “And biotechnology gives the possibility of novel, non-commodity products,” said Robert Bondaryk recently at an A.D. Little-sponsored seminar here devoted to ...
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    URL: http://dx.doi.org/10.1038/nbt0986-759b
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  • 3
    Electronic Resource
    Electronic Resource
    New Survey Analyzes Biotech Finances (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 760-760 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SAN FRANCISCO—As biotechnology companies grow, more of their income is generated from product sales and less from interest, and the percentage of total spending devoted to R&D decreases. Regardless of company size, however, the growth in revenues usually exceeds the growth in expenses, ...
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    URL: http://dx.doi.org/10.1038/nbt0986-760
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  • 4
    Electronic Resource
    Electronic Resource
    EPA's Novel Idea for a ‘Suicide Plasmid’ (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 762-762 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] GULF BREEZE, Fla.—Although genetically engineered plants have finally gone to field tests, efforts to field-test recombinant microbes remain stymied by opposition and regulatory delays. The Environmental Protection Agency's Microbial Ecology and Biotechnology Branch here is trying to develop ...
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    URL: http://dx.doi.org/10.1038/nbt0986-762a
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  • 5
    Electronic Resource
    Electronic Resource
    Looking at Two–Dimensional Configurations (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 767-767 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] SCHENECTADY, N.Y.—Protein engineers could soon have a new technique to help them analyze crystal structures. The method, developed by General Electric staff biophysicist Egidijus E. Uzgiris and collaborators, allows visualization of the overall configuration of a protein sample ...
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    URL: http://dx.doi.org/10.1038/nbt0986-767
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  • 6
    Electronic Resource
    Electronic Resource
    The Bio/Technology Roundtable on Europe (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 771-778 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In the wet and windy middle of May, Bio/Technology editors Douglas McCormick and Bernard Dixon journeyed to the Wembley convention center, outside London. Over dinner, they met with seven prominent executives and researchers for a frank discussion of the state and prospects of biotechnology in ...
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    URL: http://dx.doi.org/10.1038/nbt0986-771
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  • 7
    Electronic Resource
    Electronic Resource
    Somatic Seeds: Encapsulation of Asexual Plant Embryos (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 797-801 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Somatic embryos (SE) of alfalfa, celery, and cauliflower were encapsulated as single–embryo beads approximately four millimeters in diameter to produce individual somatic (artificial) seeds. The SE were mixed in sodium alginate and dropped into a solution of calcium chloride to form calcium ...
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    URL: http://dx.doi.org/10.1038/nbt0986-797
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  • 8
    Electronic Resource
    Electronic Resource
    Embrex: The Early Bird in Poultry Biotech (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 694-694 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] RALEIGH, N.C.—The commercial poultry industry is worth a fortune. Individually, however, chickens are worth next to nothing. In fact, they are the very sort of high-volume, low-value products that biotechnologists habitually shun. So, while a number of bovine-oriented genetic engineering ...
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    URL: http://dx.doi.org/10.1038/nbt0886-694
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  • 9
    Electronic Resource
    Electronic Resource
    Protein Design: Building Better Mousetraps (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 683-683 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Understanding the intimate geometry of enzyme active sites is the key to unlocking their catalytic mechanisms. It is also essential to the near-term goal of designing enzymes with altered catalytic properties, and to the ultimate goal of de novo enzyme design. Gregory Petsko ...
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    URL: http://dx.doi.org/10.1038/nbt0886-683
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  • 10
    Electronic Resource
    Electronic Resource
    Cooperativity of Esterases and Xylanases in the Enzymatic Degradation of Acetyl Xylan (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 731-733 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Xylan exists in many plants in an acetylated form, a circumstance largely neglected in studies of its breakdown by microbial enzymes. The present investigation demonstrates that fungal esterase and xylanase activities act cooperatively in hydrolyzing acetyl xylan. In the absence of esterase, ...
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    URL: http://dx.doi.org/10.1038/nbt0886-731
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  • 11
    Electronic Resource
    Electronic Resource
    B–Cell Lymphokines: The Next Horizon (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 614-621 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] So long as we are ignorant of the true essence of the cause which is operating,” the second century Greek physician Galen wrote, “we call it a factor. Thus we say that there exists in the veins a blood-making factor, as also a pulsatile factor in the heart, and in each of the other ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nbt0786-614
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  • 12
    Electronic Resource
    Electronic Resource
    Development of a Genetically–Engineered, Candidate Polio Vaccine Employing the Self–Assembling Properties of the Tobacco Mosaic Virus Coat Protein (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 637-641 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A synthetic gene coding for the coat protein of tobacco mosaic virus (TMVCP) was expressed in E. coli under the direction of the lacUV5 promoter. Modification of the 3′ end of the TMVCP gene by insertion of a region coding for an antigenic epitope from poliovirus type 3 resulted in the ...
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    URL: http://dx.doi.org/10.1038/nbt0786-637
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  • 13
    Electronic Resource
    Electronic Resource
    Evolution, Ecology and Diagnosis: Unity in Variety (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 623-628 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Questions of natural relationships among microorganisms have provided many contentious punctuations in the history of microbiology. Yet, as microbial taxonomy became strictly determinative, these issues were viewed as more historical than fundamental, of interest but of little practical value. In ...
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    URL: http://dx.doi.org/10.1038/nbt0786-623
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  • 14
    Electronic Resource
    Electronic Resource
    Gene Transfer into Loblolly Pine by Agrobacterium tumefaciens (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 647-649 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] We have demonstrated expression of bacterial genes transferred into cells of loblolly pine (Pinus taeda L.) by Agrobacterium tumefaciens. Whereas previous surveys found pines resistant to Agrobacterium, we found two wild type strains that produce galls. Callus proliferated from these galls ...
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    URL: http://dx.doi.org/10.1038/nbt0786-647
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  • 15
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    Announcements (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 660-660 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] AUGUST MEETINGS August 10–13. Congress on Research in Lymphokines and Other Cytokines. Boston, MA. Info: Congress on Research in Lymphokines and Cytokines, c/o Scherago Associates, 1515 Broadway, New York, NY 10036 Aug. 10–15. Annual Meeting of the Society for Industrial Microbiology. ...
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    URL: http://dx.doi.org/10.1038/nbt0786-660
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  • 16
    Electronic Resource
    Electronic Resource
    Obesity Monoclonals (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 662-662 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: I read Bernard Dixon's Commentary in the March issue of Bio/Technology (p. 161) with great interest. Using antibody therapy to deplete fat depots in animals is an amazing solution to the regulatory problems related to hormonal therapy. I immediately made the connection to the ...
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    URL: http://dx.doi.org/10.1038/nbt0786-662a
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  • 17
    Electronic Resource
    Electronic Resource
    Biotechnology in Underdevelopment (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 672-672 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The assessment of the viability of biotechnology in any country must be made in the context of its biological sciences and their relationships with the productive sector. A review of these two parameters in the underdeveloped world (with the exception of the special cases of China, Cuba, and ...
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    URL: http://dx.doi.org/10.1038/nbt0786-672
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  • 18
    Electronic Resource
    Electronic Resource
    Reaching Toward the Future of Healthcare (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 490-490 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] BOSTON, Mass.—When a state governor opens a conference on biotech nology, it is not so important what the official says, but that he is there in the first place. Such was the case when this state's Gov. Michael S. Dukakis told some 200 BioExpo 86 attendees that biotechnology can be of ...
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    URL: http://dx.doi.org/10.1038/nbt0686-490
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  • 19
    Electronic Resource
    Electronic Resource
    ELISA Kits to Diagnose Fish Disease (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 499-499 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] EDINBURGH, Scotland—Furunculosis, bacterial kidney disease, and enteric redmouth are three of the infections that fish farmers will be able to detect more quickly than ever before by using dipstick tests to be marketed shortly by Aquabio Ltd. Based on highly specific monoclonal antibodies ...
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    URL: http://dx.doi.org/10.1038/nbt0686-499a
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  • 20
    Electronic Resource
    Electronic Resource
    A ‘Negative Enhancer’ Controls β–Interferon (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 503-503 
    Details
    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW BRUNSWICK, N.J.—The enhancer element of the β-interferon gene contains negative regulatory sequences. This novel result was reported by Tom Maniatis (Harvard University) speaking at the Third Waksman Institute-Bio/Technology Colloquium held here in April. Maniatis described a series ...
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    URL: http://dx.doi.org/10.1038/nbt0686-503b
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  • 21
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    A Federal Strategy for International Industrial Competitiveness (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 522-525 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] How can the U.S. high technology industries, in the face of intense international competition, continue their technological innovation for strong economic growth and development? The issue of industrial competitiveness rests in a framework of national debate on international trade, protectionism, ...
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    URL: http://dx.doi.org/10.1038/nbt0686-522
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  • 22
    Electronic Resource
    Electronic Resource
    Human Chromosome–Specific DNA Libraries: Construction and Availability (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 537-552 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The goal of the National Laboratory Gene Library Project at the Los Alamos and Lawrence Livermore National Laboratories is the production of chromosome–specific human gene libraries and their distribution to the scientific community for studies of the molecular biology of genes and ...
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    URL: http://dx.doi.org/10.1038/nbt0686-537
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  • 23
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    Electronic Resource
    Enterprises Turned Awry (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 373-373 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] So. It is done. Not wisely or well, perhaps, but it is done: While industrialists and regulators have soliloquized earnestly over the last year or so—groping towards valid principles for regulating the free release of recombinant organisms into the environment—a genetically engineered ...
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    URL: http://dx.doi.org/10.1038/nbt0586-373
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  • 24
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    Electronic Resource
    AgBiotech Products Hit Regulatory Snags (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 381-381 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—Biotechnology is front-page news once again. Three attempts to commercialize whole recombinant organisms have stumbled badly over regulatory obstacles. Advanced Genetic Sciences. The U.S. Environmental Protection Agency disclosed that Advanced Genetic Sciences (Oakland, CA) ...
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    URL: http://dx.doi.org/10.1038/nbt0586-381
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  • 25
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    Electronic Resource
    Regulating Bioengineered Veterinary Drugs (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 414-416 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Veterinary medicine is, potentially, an enormous target for commercial biotechnology. A few bioengineered veterinary products are already on the market; many more are in research and development. Some will provide improved alternatives to current therapies; others will treat or prevent animal ...
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    URL: http://dx.doi.org/10.1038/nbt0586-414
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  • 26
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    New Products (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 458-460 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Hydrophobic interaction chromatography. SynChrom, Inc. (Linden, IN) offers a non-denaturing method of protein analysis based on hydrophobicity. Mild HIC supports are macroporous spherical bonded silica derivatized with the appropriate ligand chain. Write in 600 on Reader Service Card EPR ...
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    URL: http://dx.doi.org/10.1038/nbt0586-458
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  • 27
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    Secretion of Proteins from Bacteria (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 427-431 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Secretion of foreign proteins from microorganisms in general and from Escherichia coli and Bacillus subtilis in particular is still a favoured option for the subsequent recovery of such proteins on a commercial scale. The variety of natural bacterial systems now being studied and the likely ...
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    URL: http://dx.doi.org/10.1038/nbt0586-427
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  • 28
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    Design of Proteinase–Catalyzed Synthesis of Oligopeptides in an Aqueous–Organic Biphasic System (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 452-454 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Thermolysin–catalyzed condensation of N – (benzylxycarbyl) – glycyl – glycyl – L –phenylalanyl–L–leucine ethyl ester (Z–Gly–GlyPheLeuOEt), the precursor of the des–Tyr1–leucine enkephalin from ...
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  • 29
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    Lilly is Making KS1/4 (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 462-462 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: Arthur Klausner's article on “Taking Aim at Cancer with Monoclonals” (March 1986) presented the information in an organized and easily understood manner. It also achieved something we rarely see: it placed the technology in the proper perspective for the patient. We do ...
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    URL: http://dx.doi.org/10.1038/nbt0586-462b
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  • 30
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    Quantitative Biotechnology—A New Approach (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 472-472 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The place of theory in science has yet to be completely understood. Sometimes there are theories where there is little data. There are rarely piles of data without some sort of theory, limited though it may be. I hereby propose “Bionumerology” as a domain of pseudo-scientific inquiry ...
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  • 31
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    Fast Affinity Chromatography (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 519-521 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Affinity chromatography is a well established technique that continues to find new applications. It is used not only in the classical manner for isolating and purifying proteins, but also in new and novel ways, such as immobilizing ligands to study the kinetics of biological interactions. Many ...
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    URL: http://dx.doi.org/10.1038/nbt0686-519
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  • 32
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    New Products (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 344-348 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Scanning electron microscope. The S-900 from Hitachi Scientific Instruments is claimed to be the world's highest-resolution ESM—guaranteed at 8Å at 30 KV. The device is marketed by Nissei Sangyo America (Mountain View, CA). Write in 600 on Reader Service Card Water purification ...
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    URL: http://dx.doi.org/10.1038/nbt0486-344
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  • 33
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    Chromatography: Primer and Current Practice (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 327-343 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] First the very basics: Chromatography is perhaps the single most versatile technique in the biochemist's repertoire, a powerful tool for separating complex mixtures by their components' differential migration in a specific medium. By manipulating media, instrumentation, and detectors, the ...
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  • 34
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    Who Will You Blame When the Other Guy Wins? (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 368-368 
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    ISSN: 1546-1696
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] In November, I was the keynote speaker at a biotech conference in Singapore. The meeting was formally opened by the government's Minister of Finance and Health. I was pretty impressed by what this said about that government's interest in biotechnology. Two weeks earlier, I spent a week in Osaka at ...
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    Gains, Hardships to Stem from AgBiotech (1986)
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    Nature biotechnology 4 (1986), S. 385-385 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—It is not news that America's small farmers are in financial trouble. That biotechnology will add to this problem, however, is the message of a new report from the Office of Technology Assessment (OTA). Called Technology, Public Policy, and the Changing Structure of American ...
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    Improving Human and Hybrid Monoclonals (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 392-393 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—The widespread use of human monoclonal antibodies for treating disease hinges on producing large quantities of the appropriate antibody molecules efficiently and economically. Currently, mouse monoclonal antibodies have been used to a limited extent in therapeutic trials. The ...
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    Canada: Building a Regulatory Framework (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 206-207 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Canada has not yet arrived at a national policy to guide the deliberate release of genetically engineered organisms (GEOs) into the environment. The federal Departments of Environment, Agriculture, and National Health and Welfare are responsible for protecting human health and the environment from ...
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    Free Literature (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 461-461 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Eliminate hand covers lipping. Histologists, cytologists, and others who need coverglasses placed precisely on microscope slides will benefit from this new 4-page brochure describing the Hacker-Meisei (Fairfield, NJ) Robot Coverslipping Machine. Write in 700 on Reader Service Card Calibration ...
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    A “Single” Mistake (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 462-462 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: We recently sent a news release announcing an achievement by scientists at United AgriSeeds, Inc. This resulted in a note in the January “Chronicle” section (p. 11). Unfortunately, the release contained a key clerical error in the lead paragraph stating that the research ...
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    Announcements (1986)
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    Nature biotechnology 4 (1986), S. 463-463 
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    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] JUNE MEETINGS June 2. Emerging Diagnostic Technoloies. Munich. (Also on July 14 in Chicago, IL.) Info: Robert S. First, Inc., 707 Westchester Avenue, White Plains, NY 10604 June 3–6. Analytica 86. Munich, F.R.G. Info: Gerald G. Kallman, President, Kallman Associates, Five Maple Court, ...
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    IL–2 Receptors and Their Role in Malignancy (1986)
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    Nature biotechnology 4 (1986), S. 256-257 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MIAMI—Researchers are making strides to understand interleulin-2 (IL-2) receptors in an effort to produce therapies based on this powerful lymphokine. Structure of the human IL-2 receptor gene. Numbers above the boxes refer to bases in the cDNA sequence; numbers below the boxes refer to the ...
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    ‘You Can Market Products in Japan’ (1986)
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    Nature biotechnology 4 (1986), S. 262-262 
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    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] FORT LAUDERDALE, Fla.—“It is possible to crack the Japanese market,” especially with new products that garner high reimbursement from the government, reassured Hemant K. Shah, vice president for research at Nomura Securities (New York, NY). He was directing his encouragement to ...
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    Free–Release Regulation Still up in the Air (1986)
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    Nature biotechnology 4 (1986), S. 273-275 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] WASHINGTON, D.C.—Environmental release is still the burning public policy question for biotechnology. That became clear during the Brookings Institution's February conference on biotechnology, “Introduction into the Environment of Genetically Modified Organisms: A Conference on ...
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    Genetic Analysis of Protein Folding Pathways (1986)
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    Nature biotechnology 4 (1986), S. 297-303 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Optimal application of protein engineering technology will require understanding how the amino acid sequence of a polypeptide chain specifies its spatial conformation. It is now clear that polypeptide chain folding and subunit assembly proceeds through sequential pathways involving defined ...
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    Free Literature (1986)
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    Nature biotechnology 4 (1986), S. 352-352 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Plastic ware. This 96-page 1986 catalog from Cole-Parmer Instrument (Chicago, IL) lists laboratory ware in 36 categories, from bags to vials, with application guides for selecting resins, chemical resistance, and care. Write in 701 on Reader Service Card Coated tissue-culture labware. The Matrex ...
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    Disclosure Discussion (1986)
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    Nature biotechnology 4 (1986), S. 159-159 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] To the editor: Bernard Dixon's article, “What Happened to Detail and Discussion?” (December 1985) pointed out a difficulty of applied scientists (micro-biologists) in reporting and discussing their work in public. However, he is wrong in his diagnosis that this is a new problem. The ...
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    Breathing Easier with Lung Surfactant (1986)
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    Nature biotechnology 4 (1986), S. 163-165 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] MOUNTAIN VIEW, Calif.—About 40,000 premature infants will contract respiratory distress syndrome (RDS) this year in the U.S. Despite medical treatment, some 7,000 of these babies will die, owing to their deficiency in lung surfactant. Although various replacement surfactants are being tried ...
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    Charting the Hybridoma ‘Fishing Expedition’ (1986)
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    Nature biotechnology 4 (1986), S. 171-171 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] BALTIMORE, Md.—“While we have seen impressive technological improvements, I think that one has to marvel that hybridoma technology in 1986 is basically the same technology that Milstein and Kohler gave us 10 years ago,” said Joseph Davie of the Washington University School of ...
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    Celltech Expands Across the Atlantic (1986)
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    Nature biotechnology 4 (1986), S. 177-177 
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    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] LONDON—Britain's major biotechnology company, Celltech Ltd., is seeking to increase its presence abroad. With some 90 percent of its sales already coming from outside the U.K., Celltech (Slough, U.K.) has formed an American subsidiary. Actually owned by the Boots-Celltech Diagnostics Ltd. ...
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    Biotechnology and the Food Industry: Leaping the Regulatory Hurdles (1986)
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    Nature biotechnology 4 (1986), S. 199-205 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] While adapting “classical” biotechnology to the food industry is anything but novel, new techniques—such as recombinant DNA and somatic hybridization—have the potential to affect this business dramatically. These techniques open new possibilities, from altering edible ...
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    Cloning of the Bacillus Subtilis IMP Dehydrogenase Gene and its Application to Increased Production of Guanosine (1986)
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    Nature biotechnology 4 (1986), S. 225-228 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The gene encoding inosine 5′–monophosphate dehydrogenase (IMP dehydrogenase) of Bacillus subtilis was cloned in pBR322 in Escherichia coli and subsequently subcloned into the B. subtilis plasmid, pC194. The introduction of the recombinant plasmid encoding IMP dehydrogenase to B. ...
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    The Circle of Our Felicity (1986)
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    Nature biotechnology 4 (1986), S. 751-751 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Still one thing more, fellow citizens—a wise and frugal government, which shall restrain men from injuring one another, which shall leave them otherwise free to regulate their own pursuits of industry and improvement and shall not take from the mouth of labor the bread it has earned. This is ...
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    A Lesson from Louis Pasteur on AIDS Vaccine (1986)
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    Nature biotechnology 4 (1986), S. 753-753 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] A non-medically qualified individual uses material of unknown composition and toxicity to treat patients, including a child, who may be suffering from a potentially fatal illness. The individual does not even try to obtain informed consent, but publishes patients' names and addresses to help ...
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    New Developments in Gene Cloning in Antibiotic Producing Microorganisms (1986)
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    Nature biotechnology 4 (1986), S. 786-789 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Commercially important antibiotics are produced by several classes of organisms including many of the actinomycetes (Streptomyces, Actinomadura, Actinoplanes, Micromonospora, and Nocardia species), bacilli and fungi (Cephalosporium and Penicillium species). Antibiotics can be purified from ...
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    New Products (1986)
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    Nature biotechnology 4 (1986), S. 809-811 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Retracting microtome. Hacker Instruments (Fair-field, NJ) offers the new Hacker-Bright “5030” Rotary Microtome for sectioning both paraffin and plastic embedded material. Retraction, motor drive, and interchangeable advances are featured. Write in 601 on Reader Service Card Chemical ...
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    A Salute to the Pioneers of Microbiology (1986)
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    Nature biotechnology 4 (1986), S. 681-681 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Before we lose sight of our good fortune amidst the freneticism of patents, probes, and what Spyros Andreopoulos calls “gene cloning by press conference” (See New England Journal of Medicine 302:743, 1980), let's pause and remember one thing. Microbiology is young. Measured alongside ...
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    Japan Roundup (1986)
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    Nature biotechnology 4 (1986), S. 686-686 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Showa Denko (Tokyo), the world's largest manufacturer of L-tryptophan and other amino acids and peptides, has appointed Siber Hegner as sole U.K. distributor for its products, including L-tryptophan, 5-hydroxy-L-tryptophan, L-tyrosine, and D-amino acids. Oriental Yeast Co., Ltd. (Tokyo) and Nagase ...
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    Free Literature (1986)
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    Nature biotechnology 4 (1986), S. 812-812 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Automated microbiology. Foss Food Technology Corp. (Eden Prairie, MN) offers information on its Automated Microbiology System with applications in the food industry. It includes a reagent system for handling reagent prep and dispensing, filtration unit for capturing microorganisms, epifluorescence ...
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    Researchers Probe Second–Generation t–PA (1986)
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    Nature biotechnology 4 (1986), S. 706-711 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] One sure sign of a rapidly developing field is when the next generation of products is approaching the clinic before the current generation makes it to the marketplace. This is true throughout biotechnology, but nowhere is it so evident as for the blood clot dissolver called tissue plasminogen ...
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    European Steroid Ban Sparks Controversy (1986)
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    Nature biotechnology 4 (1986), S. 688-688 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—Fall-out is beginning from the European Parliament's highly controversial decision to outlaw the use of steroid hormones in animal husbandry (see Bio/Technology 4:255, April '86). This ruling led the Commission of the European Economic Community (EEC) in Brussels to release a directive ...
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    Chronicle (1986)
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    Nature biotechnology 4 (1986), S. 696-697 
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    Notes: [Auszug] Products to the market, the field, and the clinic. Ortho Pharmaceutical Corp.'s (Raritan, NJ) OKT3 monoclonal antibody was approved by the U.S. Food and Drug Administration (FDA) for use in reversing kidney transplant rejections (see Bio/Technology 3:961, Nov. '85). Ciba-Geigy (Research Triangle ...
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    Britain's MRC Forms New Molecular Genetics Unit (1986)
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    Nature biotechnology 4 (1986), S. 762-762 
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    Notes: [Auszug] CAMBRIDGE—On October 1 Sydney Brenner will exchange his post as director of the Medical Research Council (MRC) Laboratory of Molecular Biology for the directorship of a new Molecular Genetics Unit within MRC. Despite the financial hardship currently afflicting British science, MRC has found ...
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    New Products (1986)
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    Nature biotechnology 4 (1986), S. 734-736 
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    Notes: [Auszug] Gel electrophoresis apparatus. Bethesda Research Labs (Gaithersburg, MD) offers its Model S2 electrophoresis chamber, featuring an aluminum plate for even heat distribution as well as sharkstooth combs and 0.4 mm side spacers that allow full use of 48 lanes. Write in 601 on Reader Service Card ...
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    Reuniting Science and the Human Touch (1986)
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    Nature biotechnology 4 (1986), S. 598-598 
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    Notes: [Auszug] Thomas Kuhn's scenario of scientific revolutions, setting new paradigms for interludes of “normal science,” sometimes seems an appropriate model to describe the evolution of technology too. For medical diagnostics, the mid-1980s is such a time of Kuhnian revolution—a period in ...
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    Toeprints and T7 Help Elucidate Translation (1986)
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    Nature biotechnology 4 (1986), S. 605-605 
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    Notes: [Auszug] STONY BROOK, N.Y.—What are the features of messenger RNA-30S ribosome interaction that lead to efficient translation? New insights into this question were offered at this year's Stony Brook Symposium on Molecular Biology. One group, headed by Larry Gold at the University of Colorado ...
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    Coaxing Enzymes to Act in Organic Solvents (1986)
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    Nature biotechnology 4 (1986), S. 611-611 
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    Notes: [Auszug] GAITHERSBURG, Md.—Enzymes and industrial processes have one basic incompatibility: most enzymes work in water while most processes in the chemical, petrochemical, and food industries (for example) simply don't. However, Alexander Klibanov (Massachusetts Institute of Technology) pointed out at ...
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    Unlocking IL–2's Business Potential (1986)
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    Nature biotechnology 4 (1986), S. 622-622 
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    Notes: [Auszug] Lymphokines. have always been the glamor-child of biotechnology. First, interferon bore the standard for a promising but fledgling industry. When this biological response modifier seemed to lose some of its magic in the clinic, another lymphokine, interleukin-2 (IL-2), stepped into the ...
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    New Products (1986)
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    Nature biotechnology 4 (1986), S. 656-658 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Tangential flow sampler/concentrator. Control Equipment Corp.'s (Lowell, MA) Radial Flow Filter Module is based on a tubular ceramic filter cartridge of 0.2 micron pore size. Fluid is pumped parallel to the filter surface where a pressure differential forces fluid across the filter barrier. Write ...
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    Free Literature (1986)
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    Nature biotechnology 4 (1986), S. 659-659 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Pressure drop. Technical Notes 7 from Rheodyne (Cotati, CA) allow one to predict the pressure drop caused by injectors, valves, and tubes in a preparative LC system. Write in 701 on Reader Service Card Packaging and shipping. American Type Culture Collection (Rockville, MD) has just published a ...
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    Biotech 86: Protease and Anti–Protease Engineering (1986)
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    Nature biotechnology 4 (1986), S. 698-698 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—A protein engineering workshop at Biotech 86 here, chaired by Brian S. Hartley of London's Centre for Biotechnology at Imperial College, offered particular insight into the strides made recently with two related classes of proteins—the proteases and their inhibitors. Hartley ...
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    Secretion of Mature IFN–α2 and Accumulation of Uncleaved Precursor by Bacillus subtilis Transformed with a Hybrid α–Amylase Signal Sequence–IFN–α2 Gene (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 719-725 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Bacillus subtilis was transformed with a pUB110–derived vector carrying the Bacillus amyloliquefaciens α–amylase promoter and signal sequence to which the coding sequence for mature human interferon–α2 (IFN) was accurately fused. The level of secreted IFN was at most ...
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    Free Literature (1986)
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    Nature biotechnology 4 (1986), S. 737-737 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] Cytotoxic agents. Germfree Labs, Inc. (Miami, FL) offers an educational packet, “The Safe Handling of Antineoplastics/Chemotherapeutics.” It includes original materials issued by the National Study Commission on Cytotoxic Exposure and the National Institutes of Health, and information ...
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    Words of Caution as Monoclonals Mature (1986)
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    Nature biotechnology 4 (1986), S. 604-604 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] NEW YORK—In 1980 you could start a monoclonal antibody company with a scientist and a mouse. Later, you needed a cell culture facility and an investment banker. And today you'd better have a marketing staff as well. With these words, Nigel Webb, newly appointed vice chairman of Damon Biotech ...
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    Glasgow to Form a Human Leukemia Center (1986)
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    Nature biotechnology 4 (1986), S. 607-607 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Glasgow—A Human Leukaemia Virus Centre, the first of its kind in the world, is being established here at the University of Glasgow. Supported by funds of almost £2 million over the next five years, it will be located in the department of veterinary pathology, where William Jarrett has ...
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    Cell Culture Derived Recombinant HBsAg is Highly Immunogenic and Protects Chimpanzees from Infection with Hepatitis B Virus (1986)
    [s.l.] : Nature Publishing Company
    Nature biotechnology 4 (1986), S. 630-636 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Recombinant hepatitis B surface antigen (rHBsAg) particles, secreted from Chinese hamster ovary (CHO) cells stably transfected with the S gene of HBV, are indistinguishable antigenically from HBsAg particles derived from the plasma of patients chronically infected with hepatitis B virus (HBV). The ...
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    Cloned Malaria Vaccine Enters the Clinic (1986)
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    Nature biotechnology 4 (1986), S. 384-384 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] WASHINGTON, D.C.—On March 17, human trials of the first antimalarial vaccine began. Based on a cloned repeated sequence derived from the circumsporozoite gene of the malaria parasite Plasmodium falciparum, and expressed in Escherichia coli (see Bio/Technology 3:519, June '85), the vaccine ...
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    Ecology and Rationality in Free Release (1986)
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    Nature biotechnology 4 (1986), S. 481-481 
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    Notes: [Auszug] Three solid days on the ecology of biological invasions, the first two within the portals of the Royal Society and the other by courtesy of London's Ciba Foundation, sound like a formula for intensive cerebration. Contemplating this tandem of meetings, as I did recently, was enough to suggest a ...
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    Chronicle (1986)
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    Nature biotechnology 4 (1986), S. 495-495 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] New government approvals for biotechnology products include a pesticide field-test go-ahead and two medical marketing permissions. The U.S. Environmental Protection Agency will allow Steven Lindow of the University of California (Berkeley) to perform field tests on recombinant Pseudomonas bacteria ...
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    Transformation of Poplar by Agrobacterium tumefaciens (1986)
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    Nature biotechnology 4 (1986), S. 533-536 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The ability to regenerate plants from poplar cells cultured in vitro suggests that poplars may prove a valuable model system for the application of recombinant DNA technology to deciduous trees. We report here the transformation of a hybrid Populus trichocarpa × deltoides with two strains of ...
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    Production and Characterization of Growth Hormone Releasing Factor Analogs Through Recombinant DNA and Chemical Techniques (1986)
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    Nature biotechnology 4 (1986), S. 565-568 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] A growth hormone releasing factor analog [Leu27,Hse44]GRF(1–44)lactone has been made by recombinant DNA techniques. The peptide was expressed from a multiple–copied GRF gene fused to lacZ. The monomeric GRF peptide analog with a C–terminal homoserine lactone was obtained upon ...
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    No Such Thing as No Risk (1986)
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    Nature biotechnology 4 (1986), S. 592-592 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] With the possible exception of nuclear energy, no other major scientific issue has generated as much interest or controversy as recombinant DNA research and biotechnology. The agricultural, medical, and financial prospects of rDNA technology have been fully explored in the popular media even if the ...
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    Chronicle (1986)
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    Nature biotechnology 4 (1986), S. 380-380 
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    Notes: [Auszug] The discovery of a new human T-lymphotropic virus, which might be the progenitor of HTLV-III, was reported by Max Essex of the Harvard School of Public Health at the recent American Society for Microbiology meetings. Designated HTLV-IV, the virus was isolated from healthy individuals in Senegal. It ...
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    Book Review Reviewed (1986)
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    Nature biotechnology 4 (1986), S. 159-160 
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    Notes: [Auszug] To the editor: I was disappointed in the quality of Arthur Klausner's review of my book, The Biotechnology Business: A Strategic Analysis (November '85). The review concentrates on the early chapters of the book and pays little attention to the most important chapters—8 and 9. The brief ...
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    Japan Roundup (1986)
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    Nature biotechnology 4 (1986), S. 169-169 
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    Notes: [Auszug] Nippon Chemical Research is planning to develop a monoclonal antibody-based ointment to treat herpes simplex. The company has cloned the gene coding for the antibody, and intends to introduce it into monkey renal cells. Nippon plans to begin mass production at its new genetic engineering laboratory ...
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    Taking Aim at Cancer with Monoclonal Antibodies (1986)
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    Nature biotechnology 4 (1986), S. 185-194 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Monoclonal antibodies, hailed as “magic bullets” from the very beginning, are now taking aim at cancer therapy. It is still too early to tell whether even this exquisite ammunition will be able to hit the elusive target of cancer, but possibilities abound. A monoclonal antibody, ...
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    Human Monoclonal Antibodies as Probes to Study Autoimmune and Allergic Disorders (1986)
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    Nature biotechnology 4 (1986), S. 210-218 
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    Source: Nature Archives 1869 - 2009
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: [Auszug] The ability to generate monoclonal antibodies (Mabs) of defined antigenic specificity has revolutionized modern medicine. Although the technology for the generation of human monoclonal antibodies is clearly still behind that available in rodent systems, several techniques have been devised. The ...
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    History Lessons (1986)
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    Nature biotechnology 4 (1986), S. 597-597 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The subject, for a moment, was longbows. The occasion was a roundtable dinner for ten in London, during Biotech '86. And while the group was admirably equipped to debate the strengths and weaknesses of European biotechnology (a transcript of that discussion will appear here soon), we were ...
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    Seaweed for Wound Dressing (1986)
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    Nature biotechnology 4 (1986), S. 604-604 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] LONDON—Known traditionally as the “mariner's cure,” seaweed has now come into its own as the basis for Kaltostat, a revolutionary set of natural products for the treatment of wounds. Scientists at Cair Ltd.—a new company based in Aldershot, U.K., but with production ...
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    Gymnosperm Tissue Culture: A Rare Success (1986)
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    Nature biotechnology 4 (1986), S. 607-607 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] The paper in this issue by Pramod Gupta and Don Durzan (University of California, Davis) on somatic polyembryony in sugar pine describes one of the few successes in generating somatic embryos, and in large number, in gymnosperm tissue culture. Furthermore, the team's suspension cultures were ...
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    Shuffling Genes; T4 Receptors in the Brain (1986)
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    Nature biotechnology 4 (1986), S. 483-487 
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    Notes: [Auszug] VALLEY FORGE, Pa.—Coincident with the complexities of eucaryotic gene organization are possibilities for manipulating its components. Such manipulations can be both dramatic and informative. This was clear from results presented at the Fourth Annual Smith Kline & French Laboratories ...
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    Biotech Start–Ups Turn to the Public—Again (1986)
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    Nature biotechnology 4 (1986), S. 503-503 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] NEW YORK—Initial public offerings (IPOs) are the order of the day for biotechnology companies. “It's 1983 revisited,” says Steven Zimmer, vice president of Eberstadt-Fleming (New York, NY). “The window is wide open and all the companies are filing. And that's what they ...
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    Practicum: High Performance Isolation of a Recombinant Protein on Composite Ion Exchange Media (1986)
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    Nature biotechnology 4 (1986), S. 526-527 
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    Notes: [Auszug] Isolation, the upstream segment of protein recovery, includes all separation steps that lead up to or result in, a process stream that is partially purified, particle free, and concentrated. An adsorption column or cartridge is particularly attractive for isolation because it can reduce volume and ...
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    Development of a Vibrio Bioluminescence Gene–Set to Monitor Phytopathogenic Bacteria During the Ongoing Disease Process in a Non–Disruptive Manner (1986)
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    Nature biotechnology 4 (1986), S. 560-564 
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    Notes: [Auszug] Bioluminescence (lux) genes from Vibrio fischeri were cloned as a promoter–less gene set into the broad–host–range vector, pUCD4, resulting in the recombinant plasmid pUCD607 that was mobilized into a variety of plant pathogenic and symbiotic bacteria. All bacteria harboring the ...
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    Announcements (1986)
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    Nature biotechnology 4 (1986), S. 576-576 
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    Notes: [Auszug] JULY MEETINGS July 8–9. Society for General Microbiology Fermentation Group Symposium on Carbon Substrates in Biotechnology. Billingham, U.K. Info: Meetings Assistant, Society for General Microbiology, Harvest House, 62 London Road, Reading, Berks RG1 5AS, U.K. July 13–16. Microbial ...
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    British Firms Battle Over Plant Research (1986)
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    Nature biotechnology 4 (1986), S. 379-379 
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    Notes: [Auszug] CAMBRIDGE, U.K.—Hot competition is expected for ownership of Britain's National Seed Development Organisation (NSDO). Together with part of the nearby Plant Breeding Institute (PBI), NSDO is the latest of several publicly owned bodies to be “privatized” under the Thatcher ...
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    A Novel Fermentation: The Production of R(–)–1,2–Propanediol and Acetol by Clostridium thermosaccharolyticum (1986)
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    Nature biotechnology 4 (1986), S. 651-654 
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    Notes: [Auszug] We have found that three strains of Clostridium thermosaccharolyticum produce R(–)–1,2–propanediol from a variety of sugars, including D–glucose and D–xylose. The fermentation of glucose by strain HG–8 (ATCC 31960) gave 7.9 g/l of ...
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    Pharmaceutical Intermediate Supply (1986)
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    Nature biotechnology 4 (1986), S. 661-661 
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    Notes: [Auszug] To the editor: I would like to expand on a topic mentioned in Frederick Harrison's article on “Becoming a Pharmaceutical Intermediate Supplier” (March 1986). An important issue for contract manufacturers of drug compounds or intermediates is their willingness to work with the product ...
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    In Praise of Industrial Science (1986)
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    Nature biotechnology 4 (1986), S. 661-661 
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    Notes: [Auszug] To the editor: I would like to disagree with a letter by Dr. Malcolm Rhodes (March 1986), in which he states that in 1965 “employers would probably not have permitted their [employees'] participation [in a scientific meeting].” It may have been true then that the Society for General ...
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    European Patent Convention Defended (1986)
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    Nature biotechnology 4 (1986), S. 662-662 
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    Notes: [Auszug] To the editor: When Bernard Dixon deals with the European Patent Convention (Feb. '86), he misses certain points which make the situation far more complex than the simple “EPC is wrong and must be overhauled” attitude implies. First is the question of deposit. I thoroughly agree with ...
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    Curses, Foibled Again (1986)
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    Nature biotechnology 4 (1986), S. 253-253 
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    Source: Nature Archives 1869 - 2009
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    Notes: [Auszug] Somewhere, Donald Barthelme writes of spending East Texas afternoons in the hills shooting peccadilloes—which he described as the unnatural offspring of a mating of a spotted peccary and a nine-banded armadillo. We remembered Barthelme's chimeric reminiscences recently—resting with our ...
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