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  • Drosophila
  • Springer  (7)
  • National Academy of Sciences
  • Oxford University Press
  • 1975-1979  (7)
  • 1976  (7)
Sammlung
Verlag/Herausgeber
  • Springer  (7)
  • National Academy of Sciences
  • Oxford University Press
Erscheinungszeitraum
  • 1975-1979  (7)
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Development genes and evolution 179 (1976), S. 373-392 
    ISSN: 1432-041X
    Schlagwort(e): Compound Eye ; Development ; Drosophila
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary The development of the rhabdomeric pattern in the compound eye ofDrosophila has been studied using combined transplantation and electron microscope techniques. In a first series of experiments eye imaginal discs of increasing age were implanted into larvae ready to pupate, thus losing variable amounts of the normal time for development. A sequence of differentiative abilities was found in the metamorphosed test pieces. As far as the photoreceptor cells are concerned, the most prominent steps of this sequence are: ability to form groups with other similar elements, anatomical polarization of microvilli, establishment of the rhabdomeric pattern and formation of an equator line. The stability of determination of the equator line was tested in a second experimental series. Fragment of different topographical origin within the mature eye anlage were brought to metamorphosis by implantation into larvae ready to pupate. It was found that an equator line differentiates only in those pieces which according to the published anlage maps contain the prospective equator region prior to metamorphosis. The mitotic abilities of implanted eye imaginal discs were investigated by means of “in vitro”3H-thymidine pulse-labelling and light microscope autoradiography of the differentiated test pieces. During the third larval stage the eye anlage is traversed by two consecutive mitotic waves, each one of them producing different categories of receptor cells. The first, anterior wave predominantly produces cells oriented toward the poles of the eye within the ommatidia, while the second, posterior wave gives rise to elements exclusively in an equatorial position. The dynamics of this proliferation are discussed in relation to the findings in the implantation experiments. Silver-grain counts support the possibility that at least two successive cell divisions occur in the eye anlage between labeling with tritiated thymidine and beginning of morphological differentiation. The relevance of this finding for the understanding of the concept of acquisition of competence is discussed.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Development genes and evolution 179 (1976), S. 349-372 
    ISSN: 1432-041X
    Schlagwort(e): Insect Development ; Genetic Mosaics ; Fate Maps ; Drosophila
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary Gynandromorphs with female XX-and male XO-areas result from the loss of an unstable ring-X-chromosome in the early cleavage mitoses of ring/rod-X-chromosome heterozygotes. The phenotypes of the recessive alleles on the rod-X-chromosome are expressed in the XO-areas. 377 larval gynandromorphs of the genotypeR(1)2, In(1)w vC /y w sn3Iz50e mal were examined and scored for the phenotypes of 13 paired and 10 unpaired structures (Table 2, Fig. 2). This was possible mainly by the cell-autonomous expression of aldehyde oxidase activity in soft tissues and by the comparison of the distribution of enzyme activity in wildtype and gynander larvae. The distances between pairs of structures were calculated in sturt-units (Tables 3 and 4). A morphogenetic fate map with the presumptive areas of larval structures was constructed (Fig. 3). The relative positions of the structures agree well with Poulson's fate map (Fig. 4). In addition, the distribution of phenotypes was scored in 380 adult gynandromorphs Table (5). The fate map (Fig. 5) which was constructed from these data is very similar to the fate map of larval structures. This similarity becomes even more pronounced if fate maps are constructed which contain only structures analogous in larva and imago (Table 6, Fig. 6). Therefore an attempt was made to set up an integrated morphogenetic fate map containing the presumptive areas of both larval and imaginal structures (Fig. 7). The possibilities of further blastoderm mapping are discussed.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    ISSN: 1573-4927
    Schlagwort(e): xanthommatin synthesis ; phenoxazinone synthase ; eye pigmentation ; Drosophila
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Particulate fractions from the heads of Drosophila melanogaster catalyze the conversion of o-aminophenols to phenoxazinones. This particulate enzyme is stimulated by Mn2+. It has a number of features which distinguish it clearly from the Mn2+-dependent activity found in the soluble fraction. The particulate enzyme has a characteristic developmental pattern, showing a marked increase in activity at about the time of onset of xanthommatin synthesis. In addition, it is much reduced in activity in a number of xanthommatin-deficient mutants (v, cn, st, cd, and w). We believe that the head particulate enzyme is involved in xanthommatin biosynthesis and that the developmental onset of synthesis of this pigment is brought about by the synthesis or activation of this enzyme.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Biochemical genetics 14 (1976), S. 1019-1039 
    ISSN: 1573-4927
    Schlagwort(e): sorbitol dehydrogenases ; polyols ; Drosophila ; spermatogenesis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract Experiments utilizing standard techniques of cell fractionation and disc electrophoresis have revealed the presence of three distinctly different enzymes which catalyze the oxidation of d-sorbitol in crude extracts of Drosophila melanogaster adults. These include (1) a soluble NAD-dependent sorbitol dehydrogenase (NAD-SoDHs), (2) a mitochondrial NAD-dependent sorbitol dehydrogenase (NAD-SoDHm), and (3) a soluble NADP-dependent sorbitol dehydrogenase (NADP-SoDH). The structural gene for NAD-SoDHs has been mapped to a locus between 65.3 and 65.6 on the third chromosome by means of an electrophoretic variant and a low-activity allele. Through the use of segmental aneuploidy, this gene has been localized to the region limited by salivary bands 91B–93F. Because mutants which alter either the activity or electrophoretic mobility of the soluble NAD-dependent enzyme have no significant measurable effect on the mitochondrial or NADP-dependent forms, it is suggested that the enzymes in this system are coded for autonomously by different genes.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Biochemical genetics 14 (1976), S. 347-355 
    ISSN: 1573-4927
    Schlagwort(e): Drosophila ; enzyme activity variation ; α-glycerophosphate dehydrogenase ; alcohol dehydrogenase
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Abstract The activity levels of alcohol dehydrogenase and α-glycerophosphate dehydrogenase were compared among nine species of Drosophila representing three phylogenetic groups. For any given life stage, interspecific variability in activity level was much greater for ADH than for α-GPDH. Patterns of ontogenetic expression of enzyme activity were also much more variable among species for ADH than for α-GPDH. These results are consistent with the interpretation that α-GPDH is involved with a relatively uniform adaptive function among species, whereas ADH levels may reflect variable adaptive capabilities. There is a significant correlation between ADH activities and survivorship on alcohol-treated media for these nine species.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    ISSN: 1573-3297
    Schlagwort(e): Drosophila ; geotaxis ; selection ; heritability ; correlated responses
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Psychologie
    Notizen: Abstract Selection for geotaxis was carried out with flies from a natural population ofDrosophila melanogaster; geotactic behavior was measured by means of a Hirsch classification maze. The population was initially almost neutral to gravity, and it responded to both positive (downward) and negative (upward) selection with a realized heritability of about 0.13. Stabilizing selection toward neutral gravity was carried out simultaneously. At generations 6, 9, and 10, all possible hybrid crosses between pairs of the selected populations were generated and tested. The geotactic scores of hybrids in generations 6 and 9 were not significantly different from the midparent values, while the scores of hybrids in generation 10 deviated significantly from the midparent values in the direction of positive geotaxis. The frequencies of polymorphic inversions declined in every population during selection, but the population under neutral selection seemed to maintain a higher chromosomal polymorphism than those under positive or negative selection. There was no significant depression of productivity, measured as number of progeny, in any population during nine generations of selection.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Behavior genetics 6 (1976), S. 141-143 
    ISSN: 1573-3297
    Schlagwort(e): Drosophila ; yellow mutant ; receptivity ; chromosome substitution ; backcrossing
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Psychologie
    Notizen: Abstract Yellow mutant females ofDrosophila melanogaster are more receptive to yellow males than are wild-type females. By chromosomal substitution, this enhanced receptivity has been localized to the X chromosome. repeated backcrossing between a yellow and a wild-type inbred line, with the yellow locus maintained segregating, allows the conclusion that the yellow locus itself is responsible for the enhanced female receptivity.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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