Publication Date:
2019
Description:
〈p〉Publication date: 15 January 2020〈/p〉
〈p〉〈b〉Source:〈/b〉 Journal of Hazardous Materials, Volume 382〈/p〉
〈p〉Author(s): Amanda Pereira da Costa Araújo, Nathalie Ferreira Silva de Melo, Admilton Gonçalves de Oliveira Junior, Fernando Postalli Rodrigues, Thiago Fernandes, Julya Emmanuela de Andrade Vieira, Thiago Lopes Rocha, Guilherme Malafaia〈/p〉
〈h5〉Abstract〈/h5〉
〈div〉〈p〉Microplastics (MPs) are critical emerging pollutants found in the environment worldwide; however, its toxicity in aquatic in amphibians, is poorly known. Thus, the aim of the present study is to assess the toxicological potential of polyethylene microplastics (PE MPs) in 〈em〉Physalaemus cuvieri〈/em〉 tadpoles. According to the results, tadpoles’ exposure to MP PE at concentration 60 mg/L for 7 days led to mutagenic effects, which were evidenced by the increased number of abnormalities observed in nuclear erythrocytes. The small size of erythrocytes and their nuclei area, perimeter, width, length, and radius, as well as the lower nucleus/cytoplasm ratio observed in tadpoles exposed to PE MPs confirmed its cytotoxicity. External morphological changes observed in the animal models included reduced ratio between total length and mouth-cloaca distance, caudal length, ocular area, mouth area, among others. PE MPs increased the number of melanophores in the skin and pigmentation rate in the assessed areas. Finally, PE MPs were found in gills, gastrointestinal tract, liver, muscle tissues of the tail and in the blood, a fact that confirmed MP accumulation by tadpoles. Therefore, the present study pioneering evidenced how MPs can affect the health of amphibians.〈/p〉〈/div〉
〈h5〉Graphical abstract〈/h5〉
〈div〉〈p〉〈figure〉〈img src="https://ars.els-cdn.com/content/image/1-s2.0-S0304389419310209-ga1.jpg" width="248" alt="Graphical abstract for this article" title=""〉〈/figure〉〈/p〉〈/div〉
Print ISSN:
0304-3894
Electronic ISSN:
1873-3336
Topics:
Chemistry and Pharmacology
,
Energy, Environment Protection, Nuclear Power Engineering
,
Technology
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