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  • bic Book Industry Communication::M Medicine  (3)
  • philosophy  (2)
  • ASTROPHYSICS
  • Cell & Developmental Biology
  • Organic Chemistry
  • Karolinum Press  (4)
  • Co-Action Publishing
  • English  (5)
  • 1
    Publication Date: 2023-12-21
    Description: Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects suggests novel theoretical tools to test and evaluate drug interactions seen with combinatorial drug therapy. The book provides an in-depth, yet controversial, exploration of existing tools for analysis of dose-response studies at equilibrium or steady state. The book is recommended reading for post-graduate students and researchers engaged in the study of systems biology, networks, and the pharmacodynamics of natural or industrial drugs, as well as for medical clinicians interested in drug application and combinatorial drug therapy. Even people without mathematical skills will be able to follow the pros and cons of reaction schemes and their related distribution equations. Chapter 9 is a hands-on guide for software to plot, fit and analyze ones own data.
    Keywords: R5-920 ; Drugs ; therapy ; bic Book Industry Communication::M Medicine
    Language: English
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  • 2
    Publication Date: 2023-11-17
    Description: Magnetic resonance imaging of the brain and spinal cord in patients with multiple sclerosis is crucial for diagnosis as well as monitoring and predicting disease activity. Comprehensive MR measurements including assessment of brain and spinal cord volume changes have the potential to improve patient monitoring, allow earlier detection of subclinical disease activity, and identify patients with depleted brain reserve who are at highest risk of disability progression. Cerebral atrophy measurements are now a secondary outcome of many clinical trials, although their wider use in routine clinical practice is still hampered by some technical limitations. However, evidence from clinical practice shows that assessment of brain and spinal cord volume change is feasible and has the potential to improve patient treatment.
    Description: Published
    Keywords: multiple sclerosis ; brain atrophy ; diagnosis ; measurements ; disease ; monitoring ; magnetic resonance ; cerebral atrophy ; bic Book Industry Communication::M Medicine
    Language: English
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  • 3
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    Karolinum Press
    Publication Date: 2024-04-01
    Description: Thought necessarily reflects the times. Following the tragedy of the Holocaust, this fact became ever more clear. And it may be the reason postwar philosophical texts are so difficult to understand, since they confront incomprehensibly traumatic experiences. In this first English-language translation of any of his books, Miroslav Petříček—one of the most influential and erudite Czech philosophers, and a student of Jan Patočka—argues that to exist in the second half of the twentieth century and beyond, Western philosophy has had to rewrite its tradition and its discourse, radically transforming itself. Should philosophy be capable of bearing witness to the time, Petříček contends, this metamorphosis in philosophy is necessary. Offering an original Central European perspective on postwar philosophical discourse that reflects upon the historical underpinnings of pop culture phenomena and complex philosophical schools—including Adorno, Agamben, Benjamin, Derrida, Husserl, Kracauer, and many others—Philosophy en noir is a record of this transformation.
    Keywords: B1-5802 ; 20th century ; holocaust ; philosophy ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 4
    Publication Date: 2022-05-09
    Description: Abstracts from the 9th Postgradual and 7th Postdoctoral Scientific Conference of the Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, 23–24 January 2019 Dedicated to the 50th Anniversary of the Founding of the Faculty of Pharmacy in Hradec Králové and 27th National Students’ Scientific Conference of the Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, 16–17 April, 2019.
    Description: Published
    Keywords: pharmacy ; conference ; anniversary ; science ; Charles University ; Hradec Králové ; bic Book Industry Communication::M Medicine
    Language: English
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  • 5
    Publication Date: 2022-11-11
    Description: Like the ancient ouroboros devouring its own tail, we are products of our own education, our own rules and methods of cognizing and shaping the world. As such, we are also their victims, living mostly by habit and inherited rules of conduct questioning them only in the moments of crises and sometimes even not then. The purpose of this book is to explore the nature of autopoiesis or the ability of society and its various forms to create, re-create and maintain itself, by putting it in the broader interdisciplinary perspective as having been established within the project itself. The mark of the book is its broad interdisciplinary quality, stretching from philosophy, religious studies and literary theory to new media, linguistics, and political theory.
    Description: Published
    Keywords: autopoiesis ; philosophy ; literary theory ; new media ; linguistics ; religious studies ; bic Book Industry Communication::J Society & social sciences
    Language: English
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