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  • Q1-390  (1,489)
  • thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism  (760)
  • English  (2,249)
  • 2020-2024  (2,249)
  • 1955-1959
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  • 1
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    Taylor & Francis | Routledge
    Publication Date: 2024-04-01
    Description: This collection of thirteen essays examines sociolinguistic phenomena in a wide variety of marginal environments, providing both an overview of globalizaiton on the margins and a foundation for an expanded understanding of the processes of linguistic and cultural changes at work in these settings. Taking an expansive conceptual view of margins, the volume is organized in three parts, looking at examples of marginal spaces in the nation-state, in online environments, and in the peripheries of urban locations, globally to call attention to new and changing discursive genres, patterns, practices, and identities emerging in these spaces as a result of contemporary mobilities, the evolving global economy, and socio-political changes. With previous research previously confined to the study of globalization in urban areas, this volume opens the door for further research on the complex sociolinguistic processes resulting from globalization on the margins, making this an ideal resource for students and scholars in sociolinguistics, globalization and heritage studies, new media, anthropology, and cultural studies. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution (CC-BY)
    Keywords: Hoe Gaan Dit ; Linguistic Landscape ; Gregory Richardson ; Local Linguistic Landscape ; Xuan Wang ; Transcarpathian Oblast ; Massimiliano Spotti ; Dutch Caribbean Island ; Thayse Figueira Guimarães ; Smart Phones ; Branca Falabella Fabrício ; Sami Language ; Luiz Paulo Moita-Lopes ; Center Periphery Dynamics ; Paja Foudree ; Young Men ; Fie Velghe ; Language Ideologies ; Hirut Woldemariam ; Finnish Lapland ; Elizabeth Lanza ; Bongo Flava ; Binyam Sisay Mendisu ; Calypso Music ; Eleni Mariou ; Main Characters ; Zane Goebel ; Standard Ukrainian ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFD Psycholinguistics and cognitive linguistics::CFDM Bilingualism and multilingualism ; thema EDItEUR::C Language and Linguistics::CF Linguistics::CFB Sociolinguistics ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology
    Language: English
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  • 2
    Publication Date: 2024-04-05
    Description: After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.
    Keywords: QD1-999 ; Q1-390 ; Nanoparticles ; Gene Therapy ; Immunotherapy ; bioimaging ; theranostics ; nanomaterials ; Drug delivery ; Nanomedicine ; Cancer ; Phototherapy ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Anthropogenic greenhouse gas (GHG) emissions are dramatically influencing the environment, and research is strongly committed to proposing alternatives, mainly based on renewable energy sources. Low GHG electricity production from renewables is well established but issues of grid balancing are limiting their application. Energy storage is a key topic for the further deployment of renewable energy production. Besides batteries and other types of electrical storage, electrofuels and bioderived fuels may offer suitable alternatives in some specific scenarios. This Special Issue includes contributions on the energy conversion technologies and use, energy storage, technologies integration, e-fuels, and pilot and large-scale applications.
    Keywords: Q1-390 ; QC1-999 ; n/a ; PV ; GHG savings ; lithium-ion battery (LIB) ; probability prediction ; decarbonization ; supercapacitor (SC) ; least squares support vector machine ; EV fleet forecasts ; alternative maritime power (AMP) ; Markov chain ; feasibility study ; D funding ; hybrid power system ; numerical analysis ; ship structure ; optimal sizing ; cellulosic ethanol ; electric vehicles EV ; biofuel ; green ship ; R&amp ; bulk carrier ; molten carbonate fuel cell system ; sparse Gaussian process regression ; power-to-gas ; combination method ; charging infrastructure ; jet fuel ; flow characteristics ; hybrid refinery ; LNG-fueled ship ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 4
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    Taylor & Francis | Routledge
    Publication Date: 2024-04-03
    Description: Focusing on significant and cutting-edge preoccupations within children’s literature scholarship, The Routledge Companion to Children’s Literature and Culture presents a comprehensive overview of print, digital, and electronic texts for children aged zero to thirteen as forms of world literature participating in a panoply of identity formations. Offering five distinct sections, this volume: Familiarizes students and beginning scholars with key concepts and methodological resources guiding contemporary inquiry into children’s literature Describes the major media formats and genres for texts expressly addressing children Considers the production, distribution, and valuing of children’s books from an assortment of historical and contemporary perspectives, highlighting context as a driver of content Maps how children’s texts have historically presumed and prescribed certain identities on the part of their readers, sometimes addressing readers who share some part of the author’s identity, sometimes seeking to educate the reader about a presumed “other,” and in recent decades increasingly foregrounding identities once lacking visibility and voice Explores the historical evolutions and trans-regional contacts and (inter)connections in the long process of the formation of global children’s literature, highlighting issues such as retranslation, transnationalism, transculturality, and new digital formats for considering cultural crossings and renegotiations in the production of children’s literature Methodically presented and contextualized, this volume is an engaging introduction to this expanding and multifaceted field.
    Keywords: Children's Literature ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSY Children’s and teenage literature studies: general
    Language: English
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  • 5
    Publication Date: 2024-04-11
    Description: It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. Therefore, we cannot reduce microalgae biology to what we have learned from land plants biology. However, we are still at the beginning of a comprehensive understanding of microalgae biology. Microalgae have been posited several times as prime candidates for the development of sustainable energy platforms, making thus the in-depth understanding of their biological features an important objective. Thus, the knowledge related to the basics of microalgae biology must be acquired and shared rapidly, fostering the development of potential applications. Microalgae biology has been studied for more than forty years now and more intensely since the 1970’s, when genetics and molecular biology approaches were integrated into the research programs. Recently, studies on the molecular physiology of microalgae have provided evidences on the particularities of these organisms, mainly in model species, such as Chlamydomonas reinhardtii. Of note, cellular responses in microalgae produce very interesting phenotypes, such as high lipid content in nitrogen deprived cells, increased protein content in cells under high CO2 concentrations, the modification of flagella structure and motility in basal body mutant strains, the different ancient proteins that microalgae uses to dissipate the harmful excess of light energy, the hydrogen production in cells under sulfur deprivation, to mention just a few. Moreover, several research groups are using high-throughput and data-driven technologies, including “omics” approaches to investigate microalgae cellular responses at a system-wide level, revealing new features of microalgae biology, highlighting differences between microalgae and land plants. It has been amazing to observe the efforts towards the development and optimization of new technologies required for the proper study of microalgae, including methods that opened new paths to the investigation of important processes such as regulatory mechanisms, signaling crosstalk, chemotactic mechanisms, light responses, chloroplast controlled mechanisms, among others. This is an exciting moment in microalgae research when novel data are been produced and applied by research groups from different areas, such as bioprocesses and biotechnology. Moreover, there has been an increased amount of research groups focused in the study of microalgae as a sustainable source for bioremediation, synthesis of bioproducts and development of bioenergy. Innovative strategies are combining the knowledge of basic sciences on microalgae into their applied processes, resulting in the progression of many applications that hopefully, will achieve the necessary degree of optimization for economically feasible large-scale applications. Advances on the areas of basic microalgae biology and novelties on the essential cellular processes were revealed. Progress in the applied science showed the use of the basic science knowledge into fostering translational research, proposing novel strategies for a sustainable world scenario. In this present e-book, articles presented by research groups from different scientific areas showed, successfully, the increased development of the microalgae research. Herewith, you will find articles ranging from bioprospecting regional microalgae species, through advances in microalgae molecular physiology to the development of techniques for characterization of biomass and the use of biomass into agriculture and bioenergy production. This e-book is an excellent source of knowledge for those working with microalgae basic and applied sciences, and a great opportunity for researchers from both areas to have an overview of the amazing possibilities we have for building an environmentally sustainable future once the knowledge is translated into novel applications.
    Keywords: TA1-2040 ; TP248.13-248.65 ; QK1-989 ; Q1-390 ; Biotechnology ; biomass ; Hydrogen ; bioenergy ; Nutrients ; Lipids ; Microalgae ; Biofuels ; sustainability ; Carbon Dioxide ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 6
    Publication Date: 2024-04-05
    Description: In the past two decades there have been significant advances made in understanding the cellular and molecular alterations that occur with brain ageing, as well as with our understanding of age-related brain diseases. Ageing is associated with a mid-life decline in many cognitive domains (eg. Attention, working memory, episodic memory) that progresses with advancing age and which may be potentiated by a variety of diseases. However, despite the breadth of attempts to explain it, the underlying basis for age-related memory impairment remains poorly understood. Both normal and “pathological” ageing (as in age-related neurodegenerative disorders such as Alzheimer’s disease) may be associated with overlapping and increased levels of “abnormal” pathology, and this may be a potential mediator of cognitive decline in both populations. An emerging hypothesis in this field is that metal ion dys/homeostasis may represent a primary unifying mechanism to explain age- and disease-associated memory impairment – either indirectly via an effect on disease pathogenesis, or by a direct effect on signaling pathways relevant to learning and memory. There remains a concerted worldwide effort to deliver an effective therapeutic treatment for cognitive decline associated with ageing and/or disease, which is currently an unmet need. There have been numerous clinical trials conducted specifically testing drugs to prevent cognitive decline and progression to dementia, but to date the results have been less than impressive, highlighting the urgent need for a greater understanding of the neurobiological basis of memory impairment in ageing and disease which can then drive the search for effective therapeutics.
    Keywords: RC321-571 ; Q1-390 ; Down Syndrome ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; aluminium ; Iron ; TBI ; Cognition ; Copper ; Alzheimer's disease ; Zinc ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 7
    Publication Date: 2024-04-05
    Description: Neuromorphic engineering has just reached its 25th year as a discipline. In the first two decades neuromorphic engineers focused on building models of sensors, such as silicon cochleas and retinas, and building blocks such as silicon neurons and synapses. These designs have honed our skills in implementing sensors and neural networks in VLSI using analog and mixed mode circuits. Over the last decade the address event representation has been used to interface devices and computers from different designers and even different groups. This facility has been essential for our ability to combine sensors, neural networks, and actuators into neuromorphic systems. More recently, several big projects have emerged to build very large scale neuromorphic systems. The Telluride Neuromorphic Engineering Workshop (since 1994) and the CapoCaccia Cognitive Neuromorphic Engineering Workshop (since 2009) have been instrumental not only in creating a strongly connected research community, but also in introducing different groups to each other’s hardware. Many neuromorphic systems are first created at one of these workshops. With this special research topic, we showcase the state-of-the-art in neuromorphic systems.
    Keywords: RC321-571 ; Q1-390 ; neuromorphic engineering ; Learning ; Floating gate ; Neural Network ; spike-based ; event-based ; simulation ; dynamic vision sensor ; network ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 8
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Despite the importance of mathematics in our educational systems little is known about how abstract mathematical thinking emerges. Under the uniting thread of mathematical development, we hope to connect researchers from various backgrounds to provide an integrated view of abstract mathematical cognition. Much progress has been made in the last 20 years on how numeracy is acquired. Experimental psychology has brought to light the fact that numerical cognition stems from spatial cognition. The findings from neuroimaging and single cell recording experiments converge to show that numerical representations take place in the intraparietal sulcus. Further research has demonstrated that supplementary neural networks might be recruited to carry out subtasks; for example, the retrieval of arithmetic facts is done by the angular gyrus. Now that the neural networks in charge of basic mathematical cognition are identified, we can move onto the stage where we seek to understand how these basics skills are used to support the acquisition and use of abstract mathematical concepts.
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; development ; numerosity ; gifted ; Mathematical Cognition ; algebra ; abstract ; Expertise ; Arithmetic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 9
    Publication Date: 2024-03-29
    Description: In the year 2013, ‘selfie’ was named word of the year by Oxford Dictionaries in recognition of dramatic changes in frequency, prominence, and register of the term. This drastic increase in selfie-taking was spurred by two factors. The first was the advent of smartphones equipped with front cameras and preview screens that made it easy to compose a photographic self-portrait by a process of deliberately exploring one’s image, choosing a pose, and finally taking the picture. The second key change contributing to the rise of the selfie age was the increasing availability of internet connections. It is estimated that about 50% of the world population has access to the internet today (2018; https://www.internetworldstats.com). At the end of the past century, this percentage was a mere 1%. The growth of the internet infrastructure simultaneously spurred the development of social network applications such as Facebook, Twitter, Snapchat, and Instagram, providing accessible media for sharing photographs including photographic self-portraits. However, despite their tremendous reach and popularity, selfies have so far received relatively little attention by the scientific community, especially within psychology. Thus, we proposed a Frontiers in Psychology Research Topic to expand empirical and theoretical work on the massively popular, yet scientifically unexplored, phenomenon of the selfie. The articles published in this eBook offer a multifaceted insight into current scholarly work on this topic.
    Keywords: BF1-990 ; Q1-390 ; group selfies ; self-esteem ; Human Computer Interaction (HCI) ; self-presentation ; selfie ; viewing perspective ; perception bias ; smartphones ; social media ; internet ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 10
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    Springer Nature | Palgrave Macmillan
    Publication Date: 2024-03-26
    Description: This open access book challenges the contemporary relevance of the current model of knowledge production. It argues that the full digitisation of society sharply accelerated by the COVID-19 pandemic has added extreme complexity to the world, conclusively exposing the inadequacy of our current model of knowledge creation. Addressing many of the different ways in which reality has been transformed by technology – the pervasive adoption of big data, the fetishisation of algorithms and automation, and the digitalisation of education and research – Viola examines how the rigid conceptualisation in disciplines’ division and competition is complicit of promoting a narrative which has paired computational methods with exactness and neutrality whilst stigmatising consciousness and criticality as carriers of biases and inequality. Taking the humanities as a focal point, the author retraces schisms in the field between the humanities, the digital humanities and critical digital humanities; these are embedded, she argues, within old dichotomies: sciences vs humanities, digital vs non-digital and authentic vs non-authentic. Through the analysis of personal use cases and exploring a variety of applied contexts such as digital heritage practices, digital linguistic injustice, critical digital literacy and critical digital visualisation, the book shows a third way: knowledge creation in the digital.
    Keywords: Digital Hermeneutics ; digital history ; data humanities ; digital turn ; computational methods ; metadata ; information technology ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCT Media studies
    Language: English
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  • 11
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    University of Ottawa Press / Les Presses de l’Université d’Ottawa
    Publication Date: 2024-03-26
    Description: Susanna Moodie is, of course, best known for her books 〈i〉Roughing It in the Bush〈/i〉 and 〈i〉Life in the Clearings〈/i〉, which are largely comprised of short sketches that she had previously published. What is not widely known, however, is that Moodie had a long and prolific literary career in which short sketches and tales were among her favoured genres. This book offers a selection of these narratives, most of which have been unavailable in print since the 19th century. This collection will give the reader a new understanding of Susanna Moodie's work.
    Keywords: narratives ; God ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Keywords: QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 13
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    Frontiers Media SA
    Publication Date: 2024-03-31
    Description: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.
    Keywords: QP1-981 ; Q1-390 ; Vitamin D ; Immune System ; Genomics ; vitamin D receptor ; Physiology ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 14
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Glial cells are no longer considered passive bystanders in neuronal brain circuits. Not only are they required for housekeeping and brain metabolism, they are active participants in regulating the physiological function and plasticity of brain circuits and the online control of behavior both in invertebrate and vertebrate model systems. In invertebrates, glial cells are essential for normal function of sensory organs (C. elegans) and necessary for the circadian regulation of locomotor activity (D. melanogaster). In the mamallian brain, astrocytes are implicated in the regulation of cortical brain rhythms and sleep homeostasis. Disruption of AMPA receptor function in a subset of glial cell types in mice shows behavioral deficits. Furthermore, genetic disruption of glial cell function can directly control behavioral output. Regulation of ionic gradients by glia can underlie bistability of neurons and can modulate the fidelity of synaptic transmission. Grafting of human glial progenitor cells in mouse forebrain results in human glial chimeric mice with enhanced plasticity and improved behavioral performance, suggesting that astrocytes have evolved to cope with information processing in more complex brains. Taken together, current evidence is strongly suggestive that glial cells are essential contributors to information processing in the brain. This Research Topic compiles recent research that shows how the molecular mechanisms underlying glial cell function can be dissected, reviews their impact on plasticity and behavior across species and presents novel approaches to further probe their function.
    Keywords: RC321-571 ; Q1-390 ; Cerebellum ; C. elegans ; Astrocytes ; DREADD ; Cortex ; plasticity ; Gq ; Behavior ; glia ; Hippocampus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 15
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    De Gruyter | De Gruyter
    Publication Date: 2024-04-04
    Description: The contributions in this edited volume approach poetry, narrative, and drama from the perspective of Computational Stylistics. They exemplify methods of computational textual analysis and explore the possibility of computational generation of literary texts. The volume presents a range of computational and Natural Language Processing applications to literary studies, such as motif detection, network analysis, machine learning, and deep learning.
    Keywords: Digital Humanities ; stylistics poetry ; distant reading ; thema EDItEUR::D Biography, Literature and Literary studies ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSA Literary theory ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general
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  • 16
    Publication Date: 2024-04-05
    Description: Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.
    Keywords: QD1-999 ; Q1-390 ; glucose-6-phosphate dehydrogenase ; hydroxyurea/hydroxycarbamide ; n/a ; cord blood ; screening ; hemoglobin pattern ; capillary electrophoresis ; sickle cell disease ; (recommended) screening panel ; vaso-occlusive crisis ; Guthrie spots ; newborn screening) ; foetal haemoglobin ; harmonisation ; review ; birth prevalence ; G6PD deficiency ; prevention ; end-organ damage ; thalassemia ; MALDI-TOF ; IEF ; acute chest syndrome ; India ; sickle cell and thalassaemia screening programme ; ‘Getting to Outcomes’ ; newborn screening ; hemoglobinopathy ; service users ; public health engagement ; automated HPLC ; Kaduna State ; gene therapy for haemoglobinopathies ; ?-globin gene ; methods ; neonatal screening program ; malaria ; Plasmodium vivax ; sub-Saharan Africa ; patient organisations ; health policy ; pathophysiology ; Sickle Cell Disease ; mass spectrometry ; sickle cell disorder ; neonatal screening ; non-tribal ; Nigeria ; point-of-care ; HPLC ; laboratory methods ; registry ; patient advocacy ; bone marrow transplant ; anaemia ; hemoglobinopathies ; tribal ; newborn ; burden of disease ; patient representatives ; diagnostics ; policy making ; haemolysis ; Caribbean ; high performance liquid chromatography (HPLC) ; sickle cell disease (SCD) ; implementation science ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 17
    Publication Date: 2024-04-05
    Description: In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and neural dynamics in humans. A growing body of evidence indicates that the neural dynamics (e.g., oscillations, synchrony) are important in mediating information processing and networking for various functions in the human brain. Most of previous studies on human brain dynamics, however, show correlative relationships between brain functions and patterns of neural dynamics measured by imaging methods such as electroencephalography (EEG), magnetoencephalography (MEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). In contrast, manipulative approaches by non-invasive brain stimulation (NIBS) have been developed and extensively used. These approaches include transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) such as transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), and random noise stimulation (tRNS), which can directly manipulate neural dynamics in the intact human brain. Although the neural-correlate approach is a strong tool, we think that manipulative approaches have far greater potential to show causal roles of neural dynamics in human brain functions. There have been technical challenges with using manipulative methods together with imaging methods. However, thanks to recent technical developments, it has become possible to use combined methods such as TMS–EEG coregistration. We can now directly measure and manipulate neural dynamics and analyze functional consequences to show causal roles of neural dynamics in various brain functions. Moreover, these combined methods can probe brain excitability, plasticity and cortical networking associated with information processing in the intact human brain. The contributors to this EBook have succeeded in showcasing cutting-edge studies and demonstrate the huge impact of their approaches on many areas in human neuroscience and clinical applications.
    Keywords: RC321-571 ; Q1-390 ; non-invasive brain stimulation NIBS ; TMS-EEG ; Transcranial magnetic stimulation TMS ; transcranial electric stimulation tES ; Coregistration ; Near-infrared spectroscopy NIRS ; Functional magnetic resonance imaging fMRI ; transcranial direct current stimulation tDCS ; transcranial alternating current stimulation tACS ; transcranial random noise stimulation tRNS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 18
    Publication Date: 2024-04-05
    Description: Bálint’s syndrome is named after the Hungarian physician who first reported a remarkable case of a man with complex visuospatial deficits following bilateral lesions within parietal and occipital cortex (Bálint, 1909). The syndrome has three primary symptoms: simultanagnosia (impaired spatial awareness of more than one object at time), optic ataxia (misreaching to visual targets) and ocular apraxia (described by Bálint as “psychic paralysis of gaze”). Balint’s patients not only cannot perceive more than one object at time and therefore show poor comprehension of multi-object visual scenes i.e. poor detection of all the objects present and difficulty in grasping the relationship between them; in addition they typically fail to reach towards location of the single object, which they can perceive. The deficit of the allocation of spatial attention in Balint’s syndrome has been linked to a problem in feature binding which results in illusory conjunctions. Patients with Balint’s syndrome also show deficits in global processing i.e. when integration of multiple local elements into global compound shapes is required. Consequently, Balint’s syndrome provides a unique opportunity to study the nature and neuroanatomy of human visuospatial processing, in particular multi-level object representation, spatial awareness and the distribution of visual attention. The studies collected here cover both the anatomical and the cognitive mechanisms of the different symptoms associated with the syndrome. Furthermore, the dissociations between the components of Bálints’ syndrome, in particular simultanagnosia and optic ataxia, can also co-occur with visual neglect and extinction and the different combinations of reported lesions raises a question about the status of the syndrome and whether it should be merely treated as a historical compilation of symptoms which may or may not coexist cohesively. This interesting argument is raised here.
    Keywords: RC321-571 ; Q1-390 ; posterior cortical atrophy ; Balints syndrome ; optic ataxia ; Posterior parietal cortex ; simultanagnosia ; ocular apraxia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 19
    Publication Date: 2024-04-05
    Description: The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.
    Keywords: RC321-571 ; Q1-390 ; Glaucoma ; Visceral Pain ; Calcium ; membrane guanylate cyclase ; ANF-RGC ; Gene Therapy ; Cyclic GMP ; synaptic plasticity ; trafficking ; ROS-GC ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 20
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    University of Michigan Press
    Publication Date: 2024-03-26
    Description: A brief stay in France was, for many Chinese workers and Chinese Communist Party leaders, a vital stepping stone for their careers during the cultural and political push to modernize China after World War I. For the Chinese students who went abroad specifically to study Western art and literature, these trips meant something else entirely. Set against the backdrop of interwar Paris, Paris and the Art of Transposition uncovers previously marginalized archives to reveal the artistic strategies employed by Chinese artists and writers in the early twentieth-century transnational imaginary and to explain why Paris played such a central role in the global reception of modern Chinese literature and art. While previous studies of Chinese modernism have focused on how Western modernist aesthetics were adapted or translated to the Chinese context, Angie Chau does the opposite by turning to Paris in the Chinese imaginary and discussing the literary and visual artwork of five artists who moved between France and China: the painter Chang Yu, the poet Li Jinfa, the art critic Fu Lei, the painter Pan Yuliang, and the writer Xu Xu. Chau draws the idea of transposition from music theory where it refers to shifting music from one key or clef to another, or to adapting a song originally composed for one instrument to be played by another. Transposing transposition to the study of art and literature, Chau uses the term to describe a fluid and strategic art practice that depends on the tension between foreign and familiar, new and old, celebrating both novelty and recognition—a process that occurs when a text gets placed into a fresh context.
    Keywords: modern Chinese literature, modern Chinese art, visual culture, painting, poetry, French modernism, avant-garde, translation, artist, Paris, Shanghai, museum, studio, Montparnasse, Chang Yu, Fu Lei, Xu Xu, Pan Yuliang, Li Jinfa, transposition, China, France ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art
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  • 21
    Publication Date: 2024-04-05
    Description: In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system.
    Keywords: RC321-571 ; Q1-390 ; Nervous System ; Ion Channels ; Interactome ; cellular signaling ; Protein complexes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 22
    Publication Date: 2024-04-05
    Description: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
    Keywords: QH426-470 ; Q1-390 ; Regional heritability ; prostate cancer ; infectious diseases ; MCMC ; combining studies screening ; conditional-logistic linkage ; Informatics ; autism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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  • 23
    Publication Date: 2022-01-31
    Description: This eBook presents illustrative examples of genetic chaperonopathies affecting primarily nerves and muscles and discusses molecular mechanisms and treatment targeting chaperones, i.e., chaperonotherapy.
    Keywords: Q1-390 ; small-Hsp ; Hsp60/CCT/BBS ; Indirect/Secondary Chaperonopathies ; Genetic Chaperonopathies ; Hsp40/DnaJ ; chaperonotherapy
    Language: English
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  • 24
    Publication Date: 2024-04-05
    Description: Virus-caused asthma, we now call a phenotype of asthma. Regardless of the significance and popularity of this disease, the etiology of the virus-induced asthma have not well understood. In addition, a few effective vaccines have been applied to prevent respiratory virus infection. To solve the issues, it is essential to clarify and delineate both aspects of the virus and host defense systems including acute/chronic inflammation and airway tissue remodeling. To deeply review and discuss pathophysiology and epidemiology of virus-induced asthma, this topics includes new findings of the host immunity, pathology, epidemiology, and virology of asthma/chronic obstructive pulmonary disease (COPD). We believe that these works are well summarized and informative to glimpse the field of virus- associated asthma and COPD, and may help understanding the basic and clinical aspects of the diseases.
    Keywords: QR1-502 ; QK1-989 ; Q1-390 ; virus-induced asthma ; Pathology ; respiratory virus ; human immunity ; Epidemiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 25
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    Unknown
    Liverpool University Press
    Publication Date: 2024-03-26
    Description: An Open Access edition of this work is available on Modern Languages Open (https://www.modernlanguagesopen.org/). On 12 March 2018, Mauritius celebrated fifty years as an independent nation amidst much fanfare. Yet behind the nation's official image of multicultural 'unity in diversity' lurk deep socio-economic inequalities and inter-ethnic tensions that are insistently critiqued in its literature. Against this backdrop, this book analyses how the idea of belonging - a sense of attachment to, and identification with, a place or people - is problematised in a range of contemporary francophone Mauritian novels. The island-nation's complex history and the multi-ethnic composition of its modern-day population mean that belonging is a central but fraught issue in both reality and fiction. Waters explores how diverse forms of affirmative, affective belonging intersect with, and are frequently inhibited by, exclusionary 'politics of belonging' at communal, national or international levels. Using an eclectic theoretical approach to the central concept of belonging, Waters offers in-depth textual analyses of novels by leading Mauritian writers Nathacha Appanah, Ananda Devi, Shenaz Patel, Bertrand de Robillard, Amal Sewtohul and Carl de Souza. Despite their thematic and formal diversity, these novels are shown to be characterised by a common rejection of dominant discourses of ethnic, diasporic affiliation and by a common commitment to the ongoing, future-orientated project of Mauritian nationhood. As such, this book offers an original insight into the dynamics of belonging and exclusion in diverse, multi-ethnic societies.
    Keywords: Language & Literature ; European Studies ; African Studies ; History ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general ; thema EDItEUR::N History and Archaeology::NH History::NHH African history ; thema EDItEUR::N History and Archaeology::NH History::NHD European history
    Language: English
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  • 26
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    Taylor & Francis | Routledge
    Publication Date: 2024-03-23
    Description: All Along Bob Dylan: America and the World offers an important contribution to thinking about the artist and his work. Adding European and non-English speaking contexts to the vibrant field of Dylan studies, the volume covers a wide range of topics and methodologies while dealing with the inherently complex and varied material produced or associated with the iconic artist. The chapters, organized around three broad thematic sections Geographies, Receptions and Perspectives, address the notions of audience, performance and identity, allowing to map out the structure of feeling and authenticity, both, in the case of the artist and his audience. Taking its cue from the collapse of the so-called high-/ low culture split following from the Nobel Prize, the book explores the argument that Dylan (and all popular music) can be interpreted as literature and offers discussions in the context of literary traditions, or visual culture and music. This contributes to a nuanced and complex portrayal of the seminal cultural phenomenon called Bob Dylan.
    Keywords: Persona,Young Man,Dylan’s Songs,Beatles,Follow,Subterranean Homesick Blues,Woodstock,Dylan’s Work,USA,Hard Rain’s A-Gonna Fall,Timeless,Dylan’s Career,Chimes Of Freedom,Vice Versa,Tom Joad,Country And Western,Tangled Up In Blue,Direction Home,Highway 61,Lost City Ramblers,Disengaged,Dylan’s Position,Dylan’s Performances,Heaven’s Door,Dakota,visual culture,nostalgia,iconic artist,Bob Dylan,literary traditions ; thema EDItEUR::A The Arts::AB The arts: general topics ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::A The Arts::AV Music
    Language: English
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  • 27
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    University of Michigan Press | University of Michigan Press
    Publication Date: 2024-03-26
    Description: Mongrel Nation surveys the history of the United Kingdom's African, Asian, and Caribbean populations from 1948 to the present, working at the juncture of cultural studies, literary criticism, and postcolonial theory. Ashley Dawson argues that during the past fifty years Asian and black intellectuals from Sam Selvon to Zadie Smith have continually challenged the United Kingdom's exclusionary definitions of citizenship, using innovative forms of cultural expression to reconfigure definitions of belonging in the postcolonial age. By examining popular culture and exploring topics such as the nexus of race and gender, the growth of transnational politics, and the clash between first- and second-generation immigrants, Dawson broadens and enlivens the field of postcolonial studies.
    Keywords: Britain ; sociology ; African, Asian, and Caribbean populations ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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  • 28
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Transfer cells are anatomically specialized cells optimized to support high levels of nutrient transport in plants. These cells trans-differentiate from existing cell types by developing extensive and localized wall ingrowth labyrinths to amplify plasma membrane surface area which in turn supports high densities of membrane transporters. Unsurprisingly, therefore, transfer cells are found at key anatomical sites for nutrient acquisition, distribution and exchange. Transfer cells are involved in delivery of nutrients between generations and in the development of reproductive organs and also facilitate the exchange of nutrients that characterize symbiotic associations. Transfer cells occur across all taxonomic groups in higher plants and also in algae and fungi. Deposition of wall ingrowth-like structures are also seen in “syncytia” and “giant cells” which function as feeding sites for cyst and root-knot nematodes, respectively, following their infection of roots. Consequently, the formation of highly localized wall ingrowth structures in diverse cell types appears to be an ancient anatomical adaption to facilitate enhanced rates of apoplasmic transport of nutrients in plants. In some systems a role for transfer cells in the formation of an anti-pathogen protective barrier at these symplastic discontinuities has been inferred. Remarkably, the extent of cell wall ingrowth development at a particular site can show high plasticity, suggesting that transfer cell differentiation might be a dynamic process adapted to the transport requirements of each physiological condition. Recent studies exploiting different experimental systems to investigate transfer cell biology have identified signaling pathways inducing transfer cell development and genes/gene networks that define transfer cell identity and/or are involved in building the wall ingrowth labyrinths themselves. Further studies have defined the structure and composition of wall ingrowths in different systems, leading in many instances to the conclusion that this process may involve previously uncharacterized mechanisms for localized wall deposition in plants. Since transfer cells play important roles in plant development and productivity, the latter being relevant to crop yield, especially so in major agricultural species such as wheat, barley, soybean and maize, understanding the molecular and cellular events leading to wall ingrowth deposition holds exciting promise to develop new strategies to improve plant performance, a key imperative in addressing global food security. This Research Topic presents a timely and comprehensive treatise on transfer cell biology to help define critical questions for future research and thereby generating a deeper understanding of these fascinating and important cells in plant biology.
    Keywords: QK1-989 ; Q1-390 ; Wall ingrowth ; Arabidopsis thaliana ; synctial cells ; Zea mays ; transfer cells ; endosperm transfer cells ; Giant Cells ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
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  • 29
    Publication Date: 2024-04-05
    Description: Research during the past decade highlights the strong link between appetitive feeding behavior, reward and motivation. Interestingly, stress levels can affect feeding behavior by manipulating hypothalamic circuits and brain dopaminergic reward pathways. Indeed, animals and people will increase or decrease their feeding responses when stressed. In many cases acute stress leads to a decrease in food intake, yet chronic social stressors are associated to increases in caloric intake and adiposity. Interestingly, mood disorders and the treatments used to manage these disorders are also associated with changes in appetite and body weight. These data suggest a strong interaction between the systems that regulate feeding and metabolism and those that regulate mood. This Research Topic aims to illustrate how hormonal mechanisms regulate the nexus between feeding behavior and stress. It focuses on the hormonal regulation of hypothalamic circuits and/or brain dopaminergic systems, as the potential sites controlling the converging pathways between feeding behavior and stress.
    Keywords: RC321-571 ; Q1-390 ; stress ; Obesity ; Dopamine ; Ghrelin ; Leptin ; Seasonal regulation ; feeding ; HPA axis ; Hypothalamus ; circadian rhythms ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 30
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    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: This Special Issue contains one review and five original articles, all of which address cutting-edge research in the field of water and environmental virology. The review article by Gerba and Betancourt summarizes the current status and future needs for the development of virus detection methods in water reuse systems, especially focusing on methods to assess the infectivity of enteric viruses. Original papers cover a variety of research topics, such as an environmental monitoring survey of group A rotaviruses in sewage and oysters in Japan, the occurrence and genetic diversity of noroviruses and rotaviruses in a wastewater reclamation system in China, the detection of viruses and their indicators in tanker water and its sources in Nepal, integrated culture next-generation sequencing to identify the diversity of F-specific RNA coliphages in wastewater, and the development of a portable collection and detection method for viruses from ambient air and its application to a wastewater treatment plant.
    Keywords: Q1-390 ; reuse ; aerosols ; viral indicator ; wastewater treatment ; microbial contamination ; index virus ; real-time PCR ; tanker water ; virus ; wastewater reclamation ; pathogenic virus ; infectivity ; chlorination ; molecular methods ; wastewater ; next-generation sequencing ; fecal source tracking ; oyster ; fecal-source marker ; viral contamination ; cell culture ; pathogenic microorganisms ; rotavirus ; ultraviolet disinfection ; F-specific RNA bacteriophage strain ; sewage ; waterborne gastroenteritis viruses ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 31
    Publication Date: 2024-04-05
    Description: euromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
    Keywords: RC321-571 ; Q1-390 ; Informed Consent ; Deep Brain Stimulation ; Depression ; Neurosurgery ; Movement Disorders ; Neuromodulation ; Enhancement ; Neuroethics ; Philosophy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 32
    Publication Date: 2024-03-29
    Description: The integration of multisensory information is an essential mechanism in perception and in controlling actions. Research in multisensory integration is concerned with how the information from the different sensory modalities, such as the senses of vision, hearing, smell, taste, touch, and proprioception, are integrated to a coherent representation of objects. Multisensory integration is central for action control. For instance, when you grasp for a rubber duck, you can see its size and hear the sound it produces. Moreover, identical physical properties of an object can be provided by different senses. You can both see and feel the size of the rubber duck. Even when you grasp for the rubber duck with a tool (e.g. with tongs), the information from the hand, from the effect points of the tool and from the eyes are integrated in a manner to act successfully. Over the recent decade a surge of interest in multisensory integration and action control has been witnessed, especially in connection with the idea that multiple sensory sources are integrated in an optimized way. For this perspective to mature, it will be helpful to delve deeper into the information processing mechanisms and their neural correlates, asking about the range and constraints of this mechanisms, about its localization and involved networks.
    Keywords: BF1-990 ; Q1-390 ; recalibration ; haptic ; Human Information Processing ; Vision ; Perception ; reference frame ; Acoustics ; Tool Use ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 33
    Publication Date: 2024-04-05
    Description: Volume I, entitled “Augmentation of Brain Functions: Brain-Machine Interfaces”, is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
    Keywords: RC321-571 ; Q1-390 ; microcircuits ; Brain machine interface (BMI) ; nootropics ; tDCStranscranial direct current stimulation ; neural networks ; neuroprosthesis ; TMS ; implants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 34
    Publication Date: 2024-04-05
    Description: Photosystem II is a 700-kDa membrane-protein super-complex responsible for the light-driven splitting of water in oxygenic photosynthesis. The photosystem is comprised of two 350-kDa complexes each made of 20 different polypeptides and over 80 co-factors. While there have been major advances in understanding the mature structure of this photosystem many key protein factors involved in the assembly of the complex do not appear in the holoenzyme. The mechanism for assembling this super-complex is a very active area of research with newly discovered assembly factors and subcomplexes requiring characterization. Additionally the ability to split water is inseparable from light-induced photodamage that arises from radicals and reactive O2 species generated by Photosystem II chemistry. Consequently, to sustain water splitting, a “self repair” cycle has evolved whereby damaged protein is removed and replaced so as to extend the working life of the complex. Understanding how the biogenesis and repair processes are coordinated is among several important questions that remain to be answered. Other questions include: how and when are the inorganic cofactors inserted during the assembly and repair processes and how are the subcomplexes protected from photodamage during assembly? Evidence has also been obtained for Photosystem II biogenesis centers in cyanobacteria but do these also exist in plants? Do the molecular mechanisms associated with Photosystem II assembly shed fresh light on the assembly of other major energy-transducing complexes such as Photosystem I or the cytochrome b6/f complex or indeed other respiratory complexes? The contributions to this Frontiers in Plant Science Research Topic are likely to reveal new details applicable to the assembly of a range of membrane-protein complexes, including aspects of self-assembly and solar energy conversion that may be applied to artificial photosynthetic systems. In addition, a deeper understanding of Photosystem II assembly — particularly in response to changing environmental conditions — will provide new knowledge underpinning photosynthetic yields which may contribute to improved food production and long-term food security.
    Keywords: QK1-989 ; Q1-390 ; Arabidopsis thaliana ; photoactivation ; photosynthesis ; Chlamydomonas reinhardtii ; cyanobacteria ; biogenesis ; Photosystem II ; photodamage ; Nicotiana tabacum ; Synechocystis sp. PCC 6803 ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
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  • 35
    Publication Date: 2024-04-05
    Description: Big data is revolutionizing our ability to measure and study the human brain. New technology increases the resolution of images that are being study as well as enables researchers to study the brain as it functions. These technological advances are combined with efforts to collect neuroimaging data on large numbers of subjects, in some cases longitudinally. This combination of advances in measurement and scope of studies requires novel development in the statistical analysis. Fast, scalable, robust and accurate models and approaches need to be developed to make headway on these problems. This volume represents a unique collection of researchers providing deep insights on the statistical analysis of big neuroimaging data.
    Keywords: RC321-571 ; Q1-390 ; fMRI ; Neuroscience ; functional connectivity ; EEG ; Classification ; prediction ; big data ; MEG ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 36
    Publication Date: 2024-03-29
    Description: A conversation between two people can only take place if the words intended by each speaker are successfully recognized. Spoken word recognition is at the heart of language comprehension. This automatic and smooth process remains a challenge for models of spoken word recognition. Both the process of mapping the speech signal onto stored representations for words, and the format of the representation themselves are subject to debate. So far, existing research on the nature of spoken word representations has focused mainly on native speakers. The picture becomes even more complex when looking at spoken word recognition in a second language. Given that most of the world’s speakers know and use more than one language, it is crucial to reach a more precise understanding of how bilingual and multilingual individuals encode spoken words in the mental lexicon, and why spoken word recognition is more difficult in a second language than in the native language. Current models of native spoken word recognition operate under two assumptions: (i) that listeners’ perception of the incoming speech signal is optimal; and (ii) that listeners’ lexical representations are accurate. As a result, lexical representations are easily activated, and intended words are successfully recognized. However, these assumptions are compromised when applied to a later-learned second language. For a variety of reasons (e.g., phonetic/phonological, orthographic), second language users may not perceive the speech signal optimally, and they may still be refining the motor routines needed for articulation. Accordingly, their lexical representations may differ from those of native speakers, which may in turn inhibit their selection of the intended word forms. Second language users also have to solve a larger selection challenge—having words in more than one language to choose from. Thus, for second language users, the links between perception, lexical representations, orthography, and production are all but clear. Even for simultaneous bilinguals, important questions remain about the specificity and interdependence of their lexical representations and the factors influencing cross-language word activation. This Frontiers Research Topic seeks to further our understanding of the factors that determine how multilinguals recognize and encode spoken words in the mental lexicon, with a focus on the mapping between the input and lexical representations, and on the quality of lexical representations.
    Keywords: BF1-990 ; Q1-390 ; Phonological knowledge ; Second-language speech ; bilingual and bidialectal lexicon ; spoken word recognition ; lexical access ; orthographic knowledge ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 37
    Publication Date: 2024-03-31
    Description: This forum of comprehensive reviews and research studies on distinct aspects of the pathophysiology of BAV aortopathy provides both the state of the art in the knowledge on this complex disease and novel insights into its causes and consequences. The present collection of focused papers also envisions and proposes new therapeutic strategies, novel biomarkers and original risk stratification criteria, for the improvement of patient management.
    Keywords: QP1-981 ; Q1-390 ; smooth muscle cells ; microRNAs ; aortic root ; endothelial cells ; aortic surgery ; bicuspid aortic valve ; 4DFlow analysis ; aortopathy ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 38
    Publication Date: 2024-03-29
    Description: This research topic stems from the "Interdisciplinary Approaches to Multilingualism" conference, which was hosted by the Language Research Centre at the University of Calgary. It was the first conference of its kind, which brought together the work of researchers, educators, and policy makers in the areas of first and second language acquisition from psycholinguistic and pedagogical perspectives. The goal was to provide an opportunity for participants to engage with the implications of multilingualism from a range of perspectives, including the effects of being bilingual from infancy to adulthood, the process and benefits of learning multiple languages, and the impact of multilingualism on society.
    Keywords: BF1-990 ; Q1-390 ; Developmental psycholinguistics ; second language literacy development ; Multilingualism ; psycholinguistic research methods ; Second language pedagogy ; bilingualism ; Second Language Acquisition ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 39
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 40
    Publication Date: 2024-04-05
    Description: In the last decade, sleep spindles have attracted steadily increasing attention. This interest is motivated by the many intriguing relationships between spindles and various diseases (e.g., schizophrenia, Parkinson, Alzheimer, autism, mental retardation), recovery processes (e.g., post brain stroke), and cognitive faculties (e.g., memory consolidation, intelligence, dream recall, sleep preservation). Nonetheless, a methodological wall has impeded the study of sleep spindles. Their investigation rests heavily on our ability to reliably and consistently identify spindle patterns from background EEG activity, a task involving many obstacles, including: a fuzzy definition of spindles, low inter-expert agreement on their scoring, lack of consensus on standard techniques for their automated detection, low reproducibility of observed characteristics and correlates, unavailability of large, standardized, high-quality databases, and inconsistencies in the methods used to evaluate the performance of automated detectors. The primary aims of this research topic were to bring together world-class researchers on a project designed to facilitate exchanges on methodological difficulties encountered in assessing sleep spindles and to promote standardized spindle-related resources. In preparing their contributions, authors were encouraged to use existing – or to propose new – publicly available resources for assessing sleep spindles. To allow fair and accurate comparison of reported results, the authors were also encouraged to validate their tools on a common benchmark. A database containing expert spindle scoring (i.e., the Montreal Archive of Sleep Studies) was made publicly available for that purpose.
    Keywords: RC321-571 ; Q1-390 ; Neural oscillations ; Electroencephalography (EEG) ; Sleep ; Sleep Spindles ; Memory ; IQ ; sigma waves ; automatic detection ; biomarker ; Open access ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 41
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    Frontiers Media SA
    Publication Date: 2024-03-31
    Description: Energy metabolism is central to life and altered energy expenditure (EE) is often cited as a central mechanism responsible for development of the obese phenotype. Resting EE, EE of physical activity, cold induced thermogenesis and thermic effect of feeding add to produce total EE but can also affect each other. It is thus very important that each component be well measured. Measuring energy expenditure by indirect calorimetry is extremely simple in theory but the practice if far more difficult. Taking into account temperature in small sized animals, measuring accurately the effect of activity on EE, correcting EE for body size body composition, age sex etc… add difficulties in producing reliable data. The goal of this Research Topic was to call for the practical experience of main investigators trained to practice calorimetry in order to get their feedback and the way they deal with the various and specific problems of humans and animal calorimetry. The goal is to share the questions/solutions experienced by the contributors to inititate a “guide of the good practices” that can be periodically updated and used by all those who are and will be interested in measuring energy metabolism from the 20g mouse to the human and large farm animals.
    Keywords: QP1-981 ; Q1-390 ; Body Composition ; Thermogenesis ; brown adipose tissue ; Body Size ; Energy Expenditure ; indirect calorimetry ; physical activity ; metabolic Phenotyping ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 42
    Publication Date: 2023-12-20
    Description: Landscapes have long been viewed as ‘multifunctional’, integrating ecological, economic, sociocultural, historical, and aesthetic dimensions. Landscape science and public awareness in Europe have been progressing in leaps and bounds. The challenges involved in landscape-related issues and fields, however, are multiple and refer to landscape stewardship and protection, as well as to the development of comprehensive theoretical and methodological approaches, in tandem with public sensitization and participatory governance and in coordination with appropriate top-down planning and policy instruments. Landscape-scale approaches are fundamental to the understanding of past and present cultural evolution, and are now considered to be an appropriate spatial framework for the analysis of sustainability. Methods and tools of landscape analysis and intervention have also gone a long way since their early development in Europe and the United States. Although significant progress has been made, there remain many issues which are understudied or not investigated at all—at least in a Mediterranean context. This Special Issue addresses the application of landscape theory and practice in the Eastern Mediterranean and mainly, but not exclusively, reports on the outcomes of an international conference held in Jordan, in December 2015, with the title “Landscapes of Eastern Mediterranean: Challenges, Opportunities, Prospects and Accomplishments”. The focus of this Special Issue, landscapes of the Eastern Mediterranean region, thus constitutes a timely area of research interest, not only because these landscapes have so far been understudied, but also as a rich site of strikingly variegated, long-standing multicultural human–environmental interactions. These interactions, resting on and taking shape through millennia of continuity in tradition, have been striving to adapt to technological advances, while currently juggling with manifold and multilayered socioeconomic and climate–environmental crises.
    Keywords: G1-922 ; Q1-390 ; n/a ; landscape archaeology ; Cyprus ; Landscape Character Assessment (LCA) ; Eastern Mediterranean ; Land Description Units ; stakeholders’ analysis ; UK ; local authority ; ancient sanctuaries ; East Med landscape ; Twain-born Border Lord ; Landscape Decision Support System ; mapping ; topography ; Byzantine landscape and garden art ; economy ; LCA ; classification ; churches ; Arabic-speaking ; participatory ; Landscape Risk Assessment Model ; landforms ; GIS ; planning ; typology ; Greek-speaking ; public realm ; landscape changes ; sacred space ; comparative study ; urban environment ; ideology ; political power ; Arabic landscape and garden art ; cultural sustainability ; historical maps ; religion ; rural land ; multi-functional landscapes ; Lebanon ; Mediterranean ; geographical information system ; spatial distributions ; Land Description Unit (LDU) ; political sustainability ; landscape ; landscape character assessment ; governance ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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    Brill | Brill
    Publication Date: 2024-03-26
    Description: Configuring Masculinity in Theory and Literary Practice combines a critical survey of the most important concepts in Masculinity Studies with a historical overview of how masculinity has been constructed within British Literature and a special focus on developments in the 20th and 21st centuries. Readership: This book is of key interest to students, university teachers, and researchers in the fields of British Literature, Gender, Masculinity, and Cultural Studies as well as Literary Studies generally.
    Keywords: Literature: history & criticism ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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  • 44
    Publication Date: 2023-12-21
    Description: Aflatoxins are a group of polyketide mycotoxins that are produced mainly by members of the genus Aspergillus. Production of these toxic secondary metabolites is closely related to fungal development (Keller et al., 2005; Jamali et al., 2012). Contamination of food, feed and agricultural commodities by aflatoxins poses enormous economic and serious health concerns because these chemicals are highly carcinogenic and can directly influence the structure of DNA. The resulting genetic defects can lead to fetal misdevelopment and miscarriages; aflatoxins are also known to suppress immune systems (Razzaghi-Abyaneh et al., 2013). In a global context, aflatoxin contamination is a constant concern between the 35N and 35S latitude where developing countries are mainly situated. With expanding boundaries of developing countries, aflatoxin contamination has become a persistent problem to those emerging areas (Shams-Ghahfarokhi et al., 2013). The continuing threat by aflatoxin contamination of food, feed and agricultural commodities to the world population has made aflatoxin research one of the most exciting and rapidly developing study areas of microbial toxins. The present research topic includes six review articles, three mini reviews and four original research articles. Contributors highlight current global health issues arising from aflatoxins and aflatoxigenic fungi and cover important aspects of aflatoxin research including contamination of crops, epidemiology, molecular biology and management strategies. Special attention is given to fungus-plant host interactions, biodiversity and biocontrol, sexual recombination in aflatoxigenic aspergilli, potential biomarkers for aflatoxin exposure in humans and safe storage programs.
    Keywords: R5-920 ; QR1-502 ; Q1-390 ; TX341-641 ; genetic diversity ; Public Health ; Aspergillus flavus ; Genomics ; MicroRNAs ; Fungus host interactions ; biological control ; aflatoxin ; agricultural crops ; bic Book Industry Communication::M Medicine
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  • 45
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    De Gruyter | De Gruyter
    Publication Date: 2024-03-26
    Description: This book explores the history of literature as a history of changing media and modes of communication, from manuscript to print, from the codex to the computer, and from paper to digital platforms. It argues that literature has evolved, and continues to evolve, in sync with material forms and formats that engage our senses in multiple ways. Because literary experiences are embedded in, and enabled by, media, the book focuses on literature as a changing combination of material and immaterial features. The principal agents of this history are no longer genres, authors, and texts but configurations of media and technologies. In telling the story of these combinations from prehistory to the present, Ingo Berensmeyer distinguishes between three successive dominants of media usage that have shaped literary history: performance, representation, and connection. Using English literature as a test case for a long view of media history, this book combines an unusual bird’s eye view across periods with illuminating readings of key texts. It will prove an invaluable resource for teaching and for independent study in English or comparative literature and media studies.
    Keywords: Media ; literature ; history ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCT Media studies
    Language: English
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  • 46
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    Firenze University Press
    Publication Date: 2024-03-23
    Description: Benjamin G. Kohl (1938-2010) taught at Vassar College from 1966 till his retirement as Andrew W. Mellon Professor of the Humanities in 2001. His doctoral research at The Johns Hopkins University was directed by Frederic C. Lane, and his principal historical interests focused on northern Italy during the Renaissance, especially on Padua and Venice. His scholarly production includes the volumes Padua under the Carrara, 1318-1405 (1998), and Culture and Politics in Early Renaissance Padua (2001), and the online database The Rulers of Venice, 1332-1524 (2009). The database is eloquent testimony of his priority attention to historical sources and to their accessibility, and also of his enthusiasm for collaboration and sharing among scholars.
    Keywords: thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art ; thema EDItEUR::6 Style qualifiers::6M Styles (M)::6MB Medieval style ; thema EDItEUR::3 Time period qualifiers::3K CE period up to c 1500::3KL c 1000 CE to c 1500::3KLY 15th century, c 1400 to c 1499 ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day::3MD 16th century, c 1500 to c 1599 ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::N History and Archaeology::NH History::NHB General and world history ; thema EDItEUR::N History and Archaeology::NK Archaeology ; thema EDItEUR::N History and Archaeology::NK Archaeology::NKD Archaeology by period / region ; thema EDItEUR::L Law::LA Jurisprudence and general issues::LAF Systems of law ; thema EDItEUR::L Law::LA Jurisprudence and general issues::LAZ Legal history
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  • 47
    Publication Date: 2024-04-05
    Description: Helicases are the proteins that bind to double- or single-stranded DNA and/or RNA chains to unwind higher order structures, usually consuming energy from the hydrolysis of ATP molecules. The biological roles of helicases are associated with a variety of DNA and/or RNA metabolisms, including DNA-replication, -repair, -recombination, RNA processing, and transcription. Dysfunctions of helicases cause various diseases, such as xeroderma pigmentosum (XP), premature aging syndrome, cancer and immunodeficiency, in humans. Moreover, recent genetic analyses revealed that mutations in helicase-encoding genes are frequently found in patients of specific diseases. Some helicases regulate cellular senescence by controlling integrity of genomes, and others play a role in neuromuscular functions presumably by modulating processing of mRNAs. However, the molecular mechanisms of how helicases are regulated in order to maintain our health are not yet fully understood. In this research topic, we will focus on the expression and functions of helicases and their encoding genes, reviewing recent research progresses that provide new insights into development of clinical and pharmaceutical treatments targeting helicases.
    Keywords: QH426-470 ; Q1-390 ; DNA Repair ; Aging ; helicases ; Telomere ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: The practical importance of economic valuation information can hardly be overstated. Coastal and marine resource policy planning and management benefit from complete information on the impact of policy decisions.
    Keywords: Q1-390 ; internet survey ; open access ; contingent valuation method ; coastal management ; tourism ; Thailand ; marine ; wetlands ; harmful algae blooms ; environmental valuation ; quota ; cyanobacteria ; estuarine and coastal ecosystems ; wealth accounting ; seawater quality ; economic analysis ; remote sensing ; ecosystem restoration ; coastal ecosystems ; random utility model ; contingent behavior ; public policy ; habitat–fishery linkages ; Barbados ; coastal ecosystem services valuation ; fishery ; mangroves ; ecosystem services valuation ; coral reefs valuation ; recreational boating ; regulated open access ; non-market value ; economic valuation ; ecosystem services ; coastal ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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    The University of North Carolina Press
    Publication Date: 2024-03-26
    Description: Ellis's book confronts directly the most central issue of Kleist criticism: the essential nature and meaning of his work. Rather than provide a general survey of Kleist's writings, Ellis performs an analysis of six of his most mature works: "Der Findling", "Die Marquise von O. . .", "Das Erdbeben in Chili", "Der Zweitkampf", "Michael Kohlhaas", and "Prinz Friedrich von Homburg". Ellis draws some general conclusions about the uniquely Kleistian character of these six works which are at sharp variance with previous Kleist criticism.
    Keywords: German Studies ; Literature ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    Taylor & Francis | New Interdisciplinary Perspectives On and Beyond Autonomy | Routledge
    Publication Date: 2024-03-26
    Description: It has been a decade since Diamond’s seminal and sober work on the possibilities of ‘liberation technology’ to ‘expand political, social and economic freedom’ (Diamond 2010). Since that time, the Arab supernova has electrified Twitter’s supporters, Russian paws and exquisite Cambridge algorithms have lent on the scales of a presidential campaign via social media, and China has amassed the data and technology to control its citizenry with cold efficiency. So what of liberation technology? What do we know about its impact on political participation, expression and freedom? In this chapter I review the promise and complexities of the pursuit of freedom via liberation technology. Tracing powerful forces that have darkened liberation technology’s initial promise, I look specifically at the complexities of both access to, and activism via, social media, showing how simple and naïve characterisations of its role in political engagement are misplaced. Whilst these results would appear to suggest that oppressive regimes have already snuffed out the promise of technology to support wider freedoms, recent theorising suggests that a pathway to freedom and prosperity has been opened where both the state and society have equal strength in the technology of accountability, information, and coordination, co-investing in each other’s capacity.
    Keywords: liberation technology, Larry Diamond, political polarisation, Arab Spring, Twitter, Facebook, platforms, state-society balance ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPF Political ideologies and movements ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHM Anthropology::JHMC Social and cultural anthropology ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFA Social discrimination and social justice
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  • 52
    Publication Date: 2024-03-29
    Description: The visual system consists of hierarchically organized distinct anatomical areas functionally specialized for processing different aspects of a visual object (Felleman & Van Essen, 1991). These visual areas are interconnected through ascending feedforward projections, descending feedback projections, and projections from neural structures at the same hierarchical level (Lamme et al., 1998). Accumulating evidence from anatomical, functional and theoretical studies suggests that these three projections play fundamentally different roles in perception. However, their distinct functional roles in visual processing are still subject to debate (Lamme & Roelfsema, 2000). The focus of this Research Topic is the roles of feedforward and feedback projections in vision. Even though the notions of feedforward, feedback, and reentrant processing are widely accepted, it has been found difficult to distinguish their individual roles on the basis of a single criterion. We welcome empirical contributions, theoretical contributions and reviews that fit into any one (or a combination) of the following domains: 1) their functional roles for perception of specific features of a visual object 2) their contributions to the distinct modes of visual processing (e.g., pre-attentive vs. attentive, conscious vs. unconscious) 3) recent techniques/methodologies to identify distinct functional roles of feedforward and feedback projections and corresponding neural signatures. We believe that the current Research Topic will not only provide recent information about feedforward/feedback processes in vision but also contribute to the understanding fundamental principles of cortical processing in general.
    Keywords: BF1-990 ; Q1-390 ; projections ; processes ; Feedback ; Vision ; feedforward ; Visual System ; mechanisms ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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    UCL Press
    Publication Date: 2024-03-26
    Description: Comparative Perspectives on the Rise of the Brazilian Novel presents a framework of comparative literature based on a systemic and empirical approach to the study of the novel and applies that framework to the analysis of key nineteenth-century Brazilian novels. The works under examination were published during the period in which the forms and procedures of the novel were acclimatized as the genre established and consolidated itself in Brazil. The 15 original essays by experienced and early career scholars explore the links between themes, narrative paradigms, and techniques of Brazilian, European and North American novels and the development of the Brazilian novel. The European and North American novels cover a wide range of literary traditions and periods, and are in conversation with the different novelistic trends that characterize the rise of the genre in Brazil. Chapters reflect on both canonical and lesser-known Brazilian works from a comparatist perspective: from the first novel by an Afro-Brazilian woman, Maria Firmina dos Reis’s Ursula (1859) to Machado de Assis’s Dom Casmurro (1900); and from José de Alencar’s Indianist novel, Iracema (1865), to Júlia Lopes de Almeida’s A Falência (The Bankruptcy, 1901).
    Keywords: Comparative literature ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
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  • 54
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    Taylor & Francis
    Publication Date: 2024-04-07
    Description: Analyzing features of Wittgenstein's philosophical work and including in-depth textual analyses, this study investigates the impact of Ludwig Wittgenstein's work on contemporary German and French novelists. Drawing upon aesthetics, architectural history, philosophy of science, and photography, the book seeks to explain why references both to Wittgenstein as a person, as well as to his work are more pervasive than other equally renowned twentieth century philosophers and asks why some authors such as Händler and Roubaud, are less well-known and only partially translated into Eng.
    Keywords: sebalds ; narratives ; wenn ; wir ; jacques ; roubaud ; text ; wittgensteins ; reflections ; warburg ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDH Philosophical traditions and schools of thought
    Language: English
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  • 55
    Publication Date: 2024-04-05
    Description: The eBook "Building Strategies for Porcine Cancer Models" presents a series of articles demonstrating the state-of-the-art developments in pig models for cancer research. Renowned researchers dedicated to the reproduction, genomic and biological engineering of the pig model for biomedicine contribute to this special research area. Although advances in these areas are occurring at surprising speeds, they are still far from realizing all the potential benefits that this biological model could provide to science. The current biomedical models may limit the frontier of knowledge in the cancer research.
    Keywords: QH426-470 ; Q1-390 ; Pigs ; Cloning ; Genetic engineering ; Comparative Genomics ; Gene Editing ; Animal Models ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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  • 56
    Publication Date: 2024-04-05
    Description: This e-book summarizes recent advances in the young and rapidly developing field of microbial volatiles. Articles included here reveal novel information about the chemical diversity of bacterial and fungal volatiles, their functions, their roles in inter-specific and inter-kingdom interactions and the metabolic and physiological changes their exposure causes in the target organisms. The e-book is divided in three chapters: (1) Natural Functions of Microbial Volatiles; (2) Volatile Production and Ecosystem Functioning and (3) Volatile Detection and Identification.
    Keywords: QR1-502 ; Q1-390 ; microorganisms ; infochemicals ; natural functions ; induced systemic resistance ; Plants ; antimicrobials ; plant growth promotion ; volatiles ; interactions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
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  • 57
    Publication Date: 2024-04-05
    Description: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 58
    Publication Date: 2023-12-20
    Description: In this eBook, Conceptual Categories and the Structure of Reality, the title very well describes the book's content. Within the book's pages a selection of academics from a variety of human behaviour, human/social science and humanities disciplines write about their research all of which can be typified by their consideration of how categories are used to structure understanding of phenomena. These authors have considered how reality may be understood through notions such as categorial and structural ontologies, part-whole relatoinships (mereology), the qualitative, quantitative and philosophical use of the facet theory approach to research, mapping sentences and declarative mapping sentence, hermeneutics, concepts and constructs, similarities and differences. The resulting collection presents the foregoing conceptual and empirical approaches to knowledge development in general (chapter 1&3 Hackett); Phillips and Wislons' review of compositional syntax in bird calls (chapter 2); neurobehavioral decision systems (chapter 4 Foxall); representations of human psychological processes (chapter 5 Juan-Miguel López-Gil; Rosa Gil; Roberto García); free associations mirroring and its relation to self- and world-related concepts (chapter 6 Martin Kuška; Radek Trnka; Aleš Antonín Kuběna; Jiří Růžička); local knowledge and going beyond the data (chapter 7 Steven Phillips); categorical etiologies of speech sound disorders (chapter 8 Kelly Farquharson); similarity of visual appearance (chapter 9 Nao Nakatsuji; Hisayasu Ihara; Takeharu Seno; Hiroshi Ito); and a consideration of the seminal writing of David Oderberg's on the categorial classification of reality (chapter 10 Hackett).
    Keywords: BF1-990 ; Q1-390 ; mereology ; similarities ; hermeneutics ; concepts ; category ; ontology ; facet theory ; declarative mapping sentence ; bic Book Industry Communication::J Society & social sciences::JM Psychology
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    Open Book Publishers
    Publication Date: 2024-03-23
    Description: " Containing ballads of martial heroism, tales of tragic lovers and visions of the nature of the world, Long Narrative Songs from the Mongghul of Northeast Tibet: Texts in Mongghul, Chinese, and English is a rich repository of songs collected amongst the Mongghul of the Seven Valleys, on the northeast Tibetan Plateau in western China. These songs represent the apogee of Mongghul oral literature, and they provide valuable insights into the lives of Mongghul people—their hopes, dreams, and worries. They bear testimony to the impressive plurilingual repertoire commanded by some Mongghul singers: the original texts in Tibetan, Mongghul, and Chinese are here presented in Mongghul, Chinese, and English. The kaleidoscope of stories told in these songs include that of Marshall Qi, a chieftain from the Seven Valleys who travels to Luoyang with his Mongghul army to battle rebels; Laarimbu and Qiimunso, a pair of star-crossed lovers who take revenge from beyond the grave on the families that kept them apart; and the Crop-Planting Song and the Sheep Song, which map the physical and spiritual terrain of the Mongghul people, vividly describing the physical and cosmological world in which they exist. This collection of songs is supported by an Introduction by Gerald Roche that provides an understanding of their traditional context, and shows that these works offer insights into the practices of multilingualism in Tibet. Long Narrative Songs from the Mongghul of Northeast Tibet is vital reading for researchers and others working on oral literature, as well as those who study Inner Asia, Tibet, and China’s ethnic minorities. Finally, this book is of interest to linguistic anthropologists and sociolinguists, particularly those working on small-scale multilingualism and pre-colonial multilingualism. "
    Keywords: narrative songs ; china’s ethnic minorities ; tibet ; pre-colonial multilingualism ; mongghul oral literature ; multilingualism ; Bird ; Gautama Buddha ; Highland barley ; Huni ; Kitchen stove ; Sheep ; thema EDItEUR::2 Language qualifiers::2G East and Southeast Asian languages::2GD Sino-Tibetan languages ; thema EDItEUR::D Biography, Literature and Literary studies::DC Poetry::DCQ Poetry anthologies (various poets) ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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  • 60
    Publication Date: 2024-03-29
    Description: Foreword by Richard J. Stevenson, Macquarie University (Australia): It was long thought that the human nose might be able to discriminate somewhere in the order of 10,000 different odourants. The recent finding that the human nose can discriminate something like a trillion different smells serves as yet another reminder that we have again underestimated the capacity of our sense of smell (Bushdid, Magnasco, Vosshall & Keller, 2014). This volume serves as a further corrective for anyone who should hold the view that olfaction is unimportant in human affairs. The papers presented in this ebook, carefully collated and overseen by Aldo Zucco, Benoist Schaal, Mats Olsson and Ilona Croy, showcase a large number of quite different reasons for studying the applied side of olfaction, and indeed human olfaction in general. The 23 contributions presented here cover a broad range of topics, which illustrate contemporary interests in our field. Although with a strong applied focus, a noteworthy feature of this ebook is the richness of the theoretical perspectives that are developed. These range from considerations of olfactory perception, memory, expertise, and priming right the way through to receptor genetics. These contributions, from many leading experts in the field, will surely shape much of the applied work linking olfaction to disease, which is a further focus of this ebook. In respect to health and disease, the chapters on aging, pregnancy, depression, alcohol dependency and environmental odours, present overviews and rich new data on many contemporary problems, to which the study of olfaction is now contributing. A particularly notable aspect of olfactory experience is the affective impact that odours can have on people and their lives. The ebook covers some particularly intriguing aspects of work in this area, with empirical studies investigating dissociations between wanting and liking, stress reduction in the elderly, mother-infant bonding, and the emotions that different odourants can evoke. This affective line of work is nicely complemented by empirical studies on expertise, the effect of odours on visual attention, and the relationship between particular personality traits and interest in olfaction. The gradual appropriation of methods from cognitive neuroscience into olfaction is also nicely represented in this ebook, with at least three of the chapters reporting data using neuroimaging, including a particular intriguing study looking at recognition of odours in mixtures. Finally, the close links between olfactory perception and sensory evaluation are also reflected in a chapter on wine. I hope that readers of this e-book will be struck, as I have been in reading its various chapters, how much olfaction affects our lives, and how the study of this sense can enrich it.
    Keywords: BF1-990 ; Q1-390 ; Disease ; Health ; Everyday Life ; Cognition ; Applied olfaction ; Expertise ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 61
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2022-01-31
    Description: This edition is a reprint of the Special Issue published online in the open access journal Remote Sensing (ISSN 2072-4292) from 2016–2017 (available at: http://www.mdpi.com/journal/remotesensing/special issues/rsALS), complemented by selected articles published in Remote Sensing
    Keywords: G1-922 ; Q1-390 ; Airborne Lidar Systems ; Data Processing
    Language: English
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  • 62
    Publication Date: 2024-04-05
    Description: Women drinking during pregnancy can result in Fetal Alcohol Spectrum Disorder (FASD), which may feature variable neurodevelopmental deficits, facial dysmorphology, growth retardation, and learning disabilities. Research suggests the human brain is precisely formed through an intrinsic, genetic-cellular expression that is carefully orchestrated by an epigenetic program. This program can be influenced by environmental inputs such as alcohol. Current research suggests the genetic and epigenetic elements of FASD are heavily intertwined and highly dependent on one another. As such, now is the time for investigators to combine genetic, genomic and epigenetic components of alcohol research into a centralized, accessible platform for discussion. Genetic analyses inform gene sets which may be vulnerable to alcohol exposure during early neurulation. Prenatal alcohol exposure indeed alters expression of gene subsets, including genes involved in neural specification, hematopoiesis, methylation, chromatin remodeling, histone variants, eye and heart development. Recently, quantitative genomic mapping has revealed loci (QTLs) that mediate alcohol-induced phenotypes identified between two alcohol-drinking mouse strains. One question to consider is (besides the role of dose and stage of alcohol exposure) why only 5% of drinking women deliver newborns diagnosed with FAS (Fetal Alcohol Syndrome)? Studies are ongoing to answer this question by characterizing genome-wide expression, allele-specific expression (ASE), gene polymorphisms (SNPs) and maternal genetic factors that influence alcohol vulnerability. Alcohol exposure during pregnancy, which can lead to FASD, has been used as a model to resolve the epigenetic pathway between environment and phenotype. Epigenetic mechanisms modify genetic outputs through alteration of 3D chromatin structure and accessibility of transcriptional machinery. Several laboratories have reported altered epigenetics, including DNA methylation and histone modification, in multiple models of FASD. During development DNA methylation is dynamic yet orchestrated in a precise spatiotemporal manner during neurulation and coincidental with neural differentiation. Alcohol can directly influence epigenetics through alterations of the methionine pathway and subsequent DNA or histone methylation/acetylation. Alcohol also alters noncoding RNA including miRNA and transposable elements (TEs). Evidence suggests that miRNA expression may mediate ethanol teratology, and TEs may be affected by alcohol through the alteration of DNA methylation at its regulatory region. In this manner, the epigenetic and genetic components of FASD are revealing themselves to be mechanistically intertwined. Can alcohol-induced epigenomic alterations be passed across generations? Early epidemiological studies have revealed infants with FASD-like features in the absence of maternal alcohol, where the fathers were alcoholics. Novel mechanisms for alcohol-induced phenotypes include altered sperm DNA methylation, hypomethylated paternal allele and heritable epimutations. These studies predict the heritability of alcohol-induced epigenetic abnormalities and gene functionality across generations. We opened a forum to researchers and investigators the field of FASD to discuss their insights, hypotheses, fresh data, past research, and future research themes embedded in this rising field of the genetics and epigenetics of FASD. This eBook is a product of the collective sharing and debate among researchers who have contributed or reviewed each subject.
    Keywords: QH426-470 ; QH301-705.5 ; Q1-390 ; DNA Methylation ; Fetal Alcohol Syndrome ; histone modification ; Epigenetic medicine ; Genomics ; Alcoholism ; transgenerational ; Pregnancy drinking ; FASD ; Gene environmental interaction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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  • 63
    Publication Date: 2024-04-05
    Description: The brain of each animal shows specific traits that reflect its phylogenetic history and its particular lifestyle. Therefore, comparing brains is not just a mere intellectual exercise, but it helps understanding how the brain allows adaptive behavioural strategies to face an ever-changing world and how this complex organ has evolved during phylogeny, giving rise to complex mental processes in humans and other animals. These questions attracted scientists since the times of Santiago Ramon y Cajal one of the founders of comparative neurobiology. In the last decade, this discipline has undergone a true revolution due to the analysis of expression patterns of morphogenetic genes in embryos of different animals. The papers of this e-book are good examples of modern comparative neurobiology, which mainly focuses on the following four Grand Questions: a) How are different brains built during ontogeny? b) What is the anatomical organization of mature brains and how can they be compared? c) How do brains work to accomplish their function of ensuring survival and, ultimately, reproductive success? d) How have brains evolved during phylogeny? The title of this e-book, Adaptive Function and Brain Evolution, stresses the importance of comparative studies to understand brain function and, the reverse, of considering brain function to properly understand brain evolution. These issues should be taken into account when using animals in the research of mental function and dysfunction, and are fundamental to understand the origins of the human mind.
    Keywords: RC321-571 ; Q1-390 ; comparative neurobiology ; brain evolution ; phylogeny ; ontogeny ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 64
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    Liverpool University Press | Liverpool University Press
    Publication Date: 2024-03-26
    Description: Terraforming is the process of making other worlds habitable for human life. Its counterpart on Earth—geoengineering— is receiving serious consideration as a way to address climate change. Contemporary environmental awareness and our understanding of climate change is influenced by science fiction, and terraforming in particular has offered scientists, philosophers, and others a motif for thinking in complex ways about our impact on planetary environments. This book asks how science fiction has imagined how we shape both our world and other planets and how stories of terraforming reflect on science, society and environmentalism. It traces the growth of the motif of terraforming in science fiction from H.G. Wells's The War of the Worlds (1898) to James Cameron's blockbuster Avatar (2009), in stories by such writers as Olaf Stapledon, Ray Bradbury, Robert Heinlein, Arthur C. Clarke, Frank Herbert, Ursula K. Le Guin, Ernest Callenbach, Pamela Sargent, Frederick Turner and Kim Stanley Robinson. It argues for terraforming as a nexus for environmental philosophy, the pastoral, ecology, the Gaia hypothesis, and the politics of colonisation and habitation. Amidst contemporary anxieties about climate change, terraforming offers an important vantage from which to consider the ways humankind shapes and is shaped by their world.
    Keywords: Literary Criticism ; Subjects & Themes ; Politics ; Literary Criticism ; Science Fiction & Fantasy ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSK Literary studies: fiction, novelists and prose writers
    Language: English
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  • 65
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Satellite Earth observation (EO) data have already exceeded the petabyte scale and are increasingly freely and openly available from different data providers. This poses a number of issues in terms of volume (e.g., data volumes have increased 10
    Keywords: G1-922 ; Q1-390 ; knowledge base ; metadata ; Synthetic Aperture Radar ; versioning ; web services ; web application ; sustainable development goals ; earth observations ; FAIR principles ; land cover classification ; semantic enrichment ; satellite imagery ; imagery ; analysis ; information extraction ; ARD ; analysis ready data ; swiss DC ; data cube ; Open Data Cube ; UN 2030 Agenda for Sustainable Development ; time-series ; graph data ; Digital Earth Australia ; query store ; open data cube ; pyroSAR ; R ; earth oberservation ; image cube ; sentinel ; open science ; Sentinel ; reproducibility ; change ; big EO data ; earth observation ; big Earth data ; Earth Observations ; Australia ; geospatial standards ; big earth data ; visualization ; UN System of Environmental Economic Accounting ; interferometric coherence ; dynamic data citation ; intelligent semantic agents ; data curation ; snow cover ; big data ; Analysis Ready Data ; climate change ; topology based map algebra ; data provenance ; Sentinel-1 ; Sentinel-2 ; remote sensing ; interoperability ; image data cube ; optical remote sensing ; dual-polarimetric decomposition ; GIS ; Gran Paradiso National Park ; data sharing ; SAR ; map algebra ; Earth observation ; Armenian DC ; data cubes ; Data Cube ; data discovery ; Earth observation data ; persistent identifier ; Landsat ; GRASS GIS ; subset ; landsat ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Language: English
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  • 66
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    Open Book Publishers
    Publication Date: 2024-04-07
    Description: This book is a treasure trove comprising core writings from Hans Walter Gabler‘s seminal work on James Joyce, spanning fifty years from the analysis of composition he undertook towards a critical text of A Portrait of the Artist as a Young Man, through the Critical and Synoptic Edition of Ulysses, to Gabler‘s latest essays on (appropriately enough) Joyce’s sustained artistic innovation. Not only does this span of essays trace the evolution of Gabler’s thinking about Joyce’s originality and creative energy. It also reflects the development and maturation of Gabler‘s own genetic criticism and his methodology of genetic editing, which grows in depth and complexity across the collection. The reader will explore Joyce’s life and works through Gabler’s incisive eye, while also examining a progress of his reflections on his edition of Ulysses and the past controversy that beset it. This classic compendium combining well-seasoned scholarship and fresh criticism is an essential read for critics of Modernism, digital humanists, scholars and students of James Joyce, and anyone interested in the art of literary analysis.
    Keywords: James Joyce;Composition analysis;Genetic editing;Joyce's Ulysses;Literary analysis ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSK Literary studies: fiction, novelists and prose writers ; thema EDItEUR::U Computing and Information Technology ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general::DSBH Literary studies: c 1900 to c 2000
    Language: English
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  • 67
    Publication Date: 2024-04-05
    Description: The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to understand how changes at the DNA, RNA or protein level affect neuronal and synaptic function, or key signalling pathways. In turn, these models may enable understanding of key disease processes and the identification of new targets for the medicines of the future. This e-book contains original research papers and reviews that highlight either the impact of next-generation sequencing in the understanding of neurological disorders, or utilise molecular, cellular, and whole-organism models to validate disease-causing or protective sequence variants.
    Keywords: RC321-571 ; Q1-390 ; Stem Cells ; glycine receptor ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; PET imaging ; LRRK2 ; Zebrafish ; Inflammation ; GABA-A receptor ; NMDA receptors ; Intellectual Disability ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 68
    Publication Date: 2024-04-05
    Description: Biotic and abiotic stress factors deliver a huge impact on plant life. Biotic stress factors such as damage through pathogens or herbivore attack, as well as abiotic stress factors like variation in temperature, rainfall and salinity, have placed the plant kingdom under constant challenges for survival. As a consequence, global agricultural and horticultural productivity has been disturbed to a large extent. Being sessile in nature, plants cannot escape from the stress, and instead adapt changes within their system to overcome the adverse conditions. These changes include physiological, developmental and biochemical alterations within the plant body which influences the genome, proteome and metabolome profiles of the plant. Since proteins are the ultimate players of cellular behavior, proteome level alterations during and recovery period of stress provide direct implications of plant responses towards stress factors. With current advancement of modern high-throughput technologies, much research has been carried out in this field. This e-book highlights the research and review articles that cover proteome level changes during the course or recovery period of various stress factors in plant life. Overall, the chapters in this e-book has provided a wealth of information on how plants deal with stress from a proteomics perspective.
    Keywords: QK1-989 ; Q1-390 ; Infection ; signaling events during stress ; Quantitative Proteomics ; heavy metal stress ; plant proteomics ; drought ; high temperature ; Salinity ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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  • 69
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    University of Michigan Press | U of M Center For Japanese Studies
    Publication Date: 2024-03-26
    Description: This volume presents 18 eighteen essays, written by scholars from six countries, on Tanizaki Jun’ichiro (1886–1965), one of the great writers of the 20th century. The essays were originally prepared for a landmark international symposium in Venice in 1995, at which 22 speakers addressed an audience of about two hundred students and scholars in the Aula Magna of the University of Venice. Topics include Tanizaki’s fiction, plays, and film scenarios; his aesthetics; his place in Japanese intellectual history; his depiction of the West; his use of humor; and film adaptations of his works. In 1964 Tanizaki was elected to honorary membership in the American Academy and Institute of Arts and Letters, the first Japanese to be so honored; and it is widely believed that he was being considered for the Nobel Prize in Literature.
    Keywords: Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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  • 70
    Publication Date: 2023-12-20
    Description: Humans are not unique in using tools. But human tool use differs from that known to occur in nonhumans in being very frequent, spontaneous, and diversified. So a fundamental issue is, what are the cognitive and neural bases of human tool use? This Research Topic of Frontiers provides a venue for leading researchers in the field of tool use to present original research papers, integrative reviews or theoretical articles that further our understanding of this topic. Articles address a wide range of issues including, for instance, the nature of the underlying representations (e.g., conceptual, sensorimotor), the mechanisms supporting the incorporation of tools into body schema, the link between imitation and tool use, or the evolutionary origins of human tool use. Articles are included from experimental psychology, neuropsychology, neuroimaging, neurophysiology, developmental psychology, ethology, comparative psychology, and ergonomics. The goal of this Research Topic of Frontiers is to provide a state-of-the-art view of the field.
    Keywords: BF1-990 ; Q1-390 ; Neural Bases ; tool use ; action ; cognitive bases ; motor control ; bic Book Industry Communication::J Society & social sciences::JM Psychology
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  • 71
    Publication Date: 2024-04-05
    Description: This special issue reviews state-of-the-art approaches to the biophysical roots of cognition. These approaches appeal to the notion that cognitive capacities serve to optimize responses to changing external conditions. Crucially, this optimisation rests on the ability to predict changes in the environment, thus allowing organisms to respond pre-emptively to changes before their onset. The biophysical mechanisms that underwrite these cognitive capacities remain largely unknown; although a number of hypotheses has been advanced in systems neuroscience, biophysics and other disciplines. These hypotheses converge on the intersection of thermodynamic and information-theoretic formulations of self-organization in the brain. The latter perspective emerged when Shannon’s theory of message transmission in communication systems was used to characterise message passing between neurons. In its subsequent incarnations, the information theory approach has been integrated into computational neuroscience and the Bayesian brain framework. The thermodynamic formulation rests on a view of the brain as an aggregation of stochastic microprocessors (neurons), with subsequent appeal to the constructs of statistical mechanics and thermodynamics. In particular, the use of ensemble dynamics to elucidate the relationship between micro-scale parameters and those of the macro-scale aggregation (the brain). In general, the thermodynamic approach treats the brain as a dissipative system and seeks to represent the development and functioning of cognitive mechanisms as collective capacities that emerge in the course of self-organization. Its explicanda include energy efficiency; enabling progressively more complex cognitive operations such as long-term prediction and anticipatory planning. A cardinal example of the Bayesian brain approach is the free energy principle that explains self-organizing dynamics in the brain in terms of its predictive capabilities – and selective sampling of sensory inputs that optimise variational free energy as a proxy for Bayesian model evidence. An example of thermodynamically grounded proposals, in this issue, associates self-organization with phase transitions in neuronal state-spaces; resulting in the formation of bounded neuronal assemblies (neuronal packets). This special issue seeks a discourse between thermodynamic and informational formulations of the self-organising and self-evidencing brain. For example, could minimization of thermodynamic free energy during the formation of neuronal packets underlie minimization of variational free energy?
    Keywords: RC321-571 ; Q1-390 ; consciousness ; understanding ; Markov blanket ; Hebbian assembly ; neuronal packet ; Bayesian brain ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 72
    Publication Date: 2024-04-05
    Description: Igneous oceanic crust is one of the largest potential habitats for life on earth, and microbial activity supported by rock-water-microbe reactions in this environment can impact global biogeochemical cycles. However, our understanding of the microbiology of this system, especially the subsurface “deep biosphere” component of it, has traditionally been limited by sample availability and quality. Over the past decade, several major international programs (such as the Center for Dark Energy Biosphere Investigations, the current International Ocean Discovery Program and its predecessor Integrated Ocean Drilling Program, and the Deep Carbon Observatory) have focused on advancing our understanding of life in this cryptic, yet globally relevant, biosphere. Additionally, many field and laboratory research programs are examining hydrothermal vent systems –a seafloor expression of seawater that has been thermally and chemically altered in subseafloor crust – and the microbial communities supported by these mineral-rich fluids. The Frontiers in Microbiology 3 September 2017 | Recent Advances in Geomicrobiology of the Ocean Crust papers in this special issue bring together recent discoveries of microbial presence, diversity and activity in these dynamic ocean environments. Cumulatively, the articles in this special issue serve as a tribute to the late Dr. Katrina J. Edwards, who was a pioneer and profound champion of studying microbes that “rust the crust”. This special issue volume serves as a foundation for the continued exploration of the subsurface ocean crust deep biosphere.
    Keywords: QR1-502 ; Q1-390 ; IODP ; deep biosphere ; hydrothermal vents ; Geomicrobiology ; ocean crust ; iron oxidation ; sulfate reduction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 73
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Keywords: QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 74
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Keywords: QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 75
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 76
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    Cornell University Press | Cornell University Press
    Publication Date: 2024-04-06
    Description: Barbara Foley here focuses on the relatively neglected genre of documentary fiction: novels that are continually near the borderline between factual and fictive discourse. She links the development of the genre over three centuries to the evolution of capitalism, but her analyses of literary texts depart significantly from those of most current Marxist critics. Foley maintains that Marxist theory has yet to produce a satisfactory theory of mimesis or of the development of genres, and she addresses such key issues as the problem of reference and the nature of generic distinctions. Among the authors whom Foley treats are Defoe, Scott, George Eliot, Joyce, Isherwood, Dos Passos, William Wells Brown, Ishmael Reed, and Ernest Gaines.
    Keywords: Literature: history and criticism ; Literary theory ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general::DSBF Literary studies: c 1800 to c 1900 ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general::DSBH Literary studies: c 1900 to c 2000 ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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    University of Michigan Press
    Publication Date: 2024-04-07
    Description: Learning Legacies explores the history of cross-cultural teaching approaches, to highlight how women writer-educators used stories about their collaborations to promote community-building. Robbins demonstrates how educators used stories that resisted dominant conventions and expectations about learners to navigate cultural differences. Using case studies of educational initiatives on behalf of African American women, Native American children, and the urban poor, Learning Legacies promotes the importance of knowledge grounded in the histories and cultures of the many racial and ethnic groups that have always comprised America’s populace, underscoring the value of rich cultural knowledge in pedagogy by illustrating how creative teachers still draw on these learning legacies today.
    Keywords: Literature ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::J Society and Social Sciences::JN Education ; thema EDItEUR::J Society and Social Sciences::JN Education::JNB History of education
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Ice crystals are the most ubiquitous material found in the cryosphere environment of the Earth, in the planetary system, and also in our daily lives. In recent years, ice crystals have increased in importance as one of the key materials for finding solutions to settle various environmental concerns at a global scale. Furthermore, ice crystals are unique materials which are potentially extremely useful in various applications, for example, within the food sciences, medical sciences, and other fields. In dealing with these interesting subjects, research on ice crystals has been more actively pursued in recent years. The Special Issue “Ice Crystals” presents a wide varieties of topics related to ice crystals. It can be considered as a status report reviewing the recent research on ice crystals and serves to provide readers with information on the latest developments concerning ice crystals.
    Keywords: Q1-390 ; QC1-999 ; coarsening kinetics ; antifreeze protein ; microstructure ; ice crystals ; decomposition ; formation ; cryo-photo microscopy ; cryoprotective agent ; ice cream ; reformation ; tomography ; deformation ; clathrate hydrate ; Negative thermal expansivity ; tetrahydrofuran ; ice crystal ; pressure ; molecular dynamics ; Grüneisen parameter ; modelling ; ab initio calculation ; freezing ; nanoscale pores ; quasi-liquid layer ; electron paramagnetic resonance ; potential of mean force ; gas hydrate ; spin labeling ; pre-decomposition pressure ; mW model ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 79
    Publication Date: 2024-04-05
    Description: Electrocochleography (ECochG) is an approach for objective measurements of physiologic responses from the inner ear. Measurements have classically been made from electrodes placed in the outer ear canal, on the tympanic membrane, the round window niche, or inside the cochlea. Recent innovations have led to ECochG being used for exciting new purposes that drive clinical practice and contribute to the basic understanding of inner ear physiology. Cochlear implant recording electrodes can monitor the preservation of residual, low-frequency acoustic hearing, both in the operating room and post-operatively. ECochG measurements can quantify differential effects of inner ear surgery or other manipulations on vestibular and auditory physiology simultaneously. Various attributes of cognitive neuroscience can be addressed with ECochG measurements from the auditory periphery. These advances in ECochG provide a way to understand a variety of inner ear diseases and are likely to be of value to many groups in their own clinical and basic research.
    Keywords: RC321-571 ; Q1-390 ; cochlear microphonic ; cochlear action potential ; sensorineural hearing loss ; compound action potential ; auditory nerve ; medial olivocochlear efferent reflex ; electrocochleography ; summating potential ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 80
    Publication Date: 2023-12-21
    Description: Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming.
    Keywords: R5-920 ; RC648-665 ; RC321-571 ; Q1-390 ; HPA axis ; Vulnerability ; resilience ; early life stress ; materna ; bic Book Industry Communication::M Medicine
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    Taylor & Francis
    Publication Date: 2024-04-07
    Description: In "Different Dispatches", David Humphries brings together in a new way a diverse group of well-known American writers of the inter-war period including: Willa Cather, Sherwood Anderson, Ernest Hemmingway, Zora Neale Hurston, James Agee and Robert Penn Warren. He demonstrates how these writers engage journalism in creating innovative texts that address mass culture as well as underlying cultural conditions. The book will be of interest to readers approaching these well-known authors for the first time or for scholars grappling with larger issues of cultural production and reception.
    Keywords: praise ; famous ; men ; individual ; reporter ; willie ; stark ; kings ; tenant ; farmers ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNT Media, entertainment, information and communication industries::KNTP Publishing industry and journalism::KNTP2 News media and journalism
    Language: English
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  • 82
    Publication Date: 2024-04-05
    Description: As a consequence of the global climate change, both the reduction on yield potential and the available surface area of cultivated species will compromise the production of food needed for a constant growing population. There is consensus about the significant gap between world food consumption projected for the coming decades and the expected crop yield-improvements, which are estimated to be insufficient to meet the demand. The complexity of this scenario will challenge breeders to develop cultivars that are better adapted to adverse environmental conditions, therefore incorporating a new set of morpho-physiological and physico-chemical traits; a large number of these traits have been found to be linked to heat and drought tolerance. Currently, the only reasonable way to satisfy all these demands is through acquisition of high-dimensional phenotypic data (high-throughput phenotyping), allowing researchers with a holistic comprehension of plant responses, or ‘Phenomics’. Phenomics is still under development. This Research Topic aims to be a contribution to the progress of methodologies and analysis to help understand the performance of a genotype in a given environment.
    Keywords: QK1-989 ; Q1-390 ; software development ; reverse phenomics ; forward phenomics ; phenotyping ; high-throughput phenotyping ; phenomics ; breeding ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: The present book contains 14 papers published in the Special Issue “Differential Geometry” of the journal Mathematics. They represent a selection of the 30 submissions. This book covers a variety of both classical and modern topics in differential geometry. We mention properties of both rectifying and affine curves, the geometry of hypersurfaces, angles in Minkowski planes, Euclidean submanifolds, differential operators and harmonic forms on Riemannian manifolds, complex manifolds, contact manifolds (in particular, Sasakian and trans-Sasakian manifolds), curvature invariants, and statistical manifolds and their submanifolds (in particular, Hessian manifolds). We wish to mention that among the authors, there are both well-known geometers and young researchers. The authors are from countries with a tradition in differential geometry: Belgium, China, Greece, Japan, Korea, Poland, Romania, Spain, Turkey, and United States of America. Many of these papers were already cited by other researchers in their articles. This book is useful for specialists in differential geometry, operator theory, physics, and information geometry as well as graduate students in mathematics.
    Keywords: QA1-939 ; Q1-390 ; statistical structure ; constant ratio submanifolds ; Euclidean submanifold ; framed helices ; Sasakian statistical manifold ; L2-harmonic forms ; Hodge–Laplacian ; complete connection ; concircular vector field ; cylindrical hypersurface ; k-th generalized Tanaka–Webster connection ; Casorati curvature ; symplectic curves ; generalized 1-type Gauss map ; rectifying submanifold ; manifold with singularity ; ruled surface ; Minkowski plane ; compact complex surfaces ; conjugate connection ; T-submanifolds ; L2-Stokes theorem ; inextensible flow ; shape operator ; generalized normalized ?-Casorati curvature ; Sasakian manifold ; centrodes ; circular helices ; non-flat complex space form ; invariant ; Frenet frame ; Darboux frame ; trans-Sasakian 3-manifold ; singular points ; symplectic curvatures ; Kähler–Einstein metrics ; conjugate symmetric statistical structure ; sectional ?-curvature ; circular rectifying curves ; developable surface ; capacity ; Ricci soliton ; Reeb flow symmetry ; Minkowskian pseudo-angle ; conical surface ; lie derivative ; position vector field ; pinching of the curvatures ; Hessian manifolds ; Minkowskian angle ; Hessian sectional curvature ; Minkowskian length ; lightlike surface ; affine sphere ; concurrent vector field ; slant ; affine hypersurface ; anti-invariant ; statistical manifolds ; Ricci operator ; C-Bochner tensor ; Ricci curvature ; real hypersurface ; scalar curvature ; framed rectifying curves ; bic Book Industry Communication::P Mathematics & science
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  • 84
    Publication Date: 2024-04-05
    Description: In the last twenty years, many attempts have been made to provide neurobiological models of autism. Functional, structural and connectivity analyses have highlighted reduced responses in key social areas, such as amygdala, medial prefrontal cortex, cingulate cortex, and superior temporal sulcus. However, these studies present discrepant results and some of them have been questioned for methodological limitations. The aim of this research topic is to present advanced neuroimaging methods able to capture the complexity of the neural deficits displayed in autism. This special issue presents new studies using structural and functional MRI, as well as magnetoencephalography, and novel protocols to analyze data (Analysis of Cluster Variability, Noise Reduction Strategies, Source-based Morphometry, Functional Connectivity Density, Restriction Spectrum Imaging and the others). We believe it is time to integrate data provided by different techniques and methodologies in order to have a better understanding of autism.
    Keywords: RC321-571 ; Q1-390 ; magnetic resonance imaging ; biomarkers ; social deficits ; autism spectrum disorder ; magnetoencephalography ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    University of Michigan Press
    Publication Date: 2024-03-26
    Description: By introducing us to the New Woman Criminal, Framed offers a profoundly different view of the fin de siècle British crime narrative
    Keywords: Literature ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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    Johns Hopkins University Press
    Publication Date: 2024-03-26
    Description: Before the Civil War, American writers such as Catharine Maria Sedgwick and Harriet Beecher Stowe had established authorship as a respectable profession for women. But though they had written some of the most popular and influential novels of the century, they accepted the taboo against female writers, regarding themselves as educators and businesswomen. During and after the Civil War, some women writers began to challenge this view, seeing themselves as artists writing for themselves and for posterity.Writing for Immortality studies the lives and works of four prominent members of the first generation of American women who strived for recognition as serious literary artists: Louisa May Alcott, Elizabeth Stuart Phelps, Elizabeth Stoddard, and Constance Fenimore Woolson. Combining literary criticism and cultural history, Anne E. Boyd examines how these authors negotiated the masculine connotation of "artist," imagining a space for themselves in the literary pantheon. Redrawing the boundaries between male and female literary spheres, and between American and British literary traditions, Boyd shows how these writers rejected the didacticism of the previous generation of women writers and instead drew their inspiration from the most prominent "literary" writers of their day: Emerson, James, Barrett Browning, and Eliot.Placing the works and experiences of Alcott, Phelps, Stoddard, and Woolson within contemporary discussions about "genius" and the "American artist," Boyd reaches a sobering conclusion. Although these women were encouraged by the democratic ideals implicit in such concepts, they were equally discouraged by lingering prejudices about their applicability to women.
    Keywords: Literature: history & criticism ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Concerns have been raised with respect to the state of high-altitude and high-latitude treelines, as they are anticipated to undergo considerable modifications due to global changes, and especially due to climate warming. As high-elevation treelines are temperature-limited vegetation boundaries, they are considered to be sensitive to climate warming. As a consequence, in this future, warmer environment, an upward migration of treelines is expected because low air and root-zone temperatures constrain their regeneration and growth. Despite the ubiquity of climate warming, treeline advancement is not a worldwide phenomenon: some treelines have been advancing rapidly, others have responded sluggishly or have remained stable. This variation in responses is attributed to the potential interaction of a continuum of site-related factors that may lead to the occurrence of locally conditioned temperature patterns. Competition amongst species and below-ground resources have been suggested as additional factors explaining the variability in the movement of treelines. This Special Issue (book) is dedicated to the discussion of treeline responses to changing environmental conditions in different areas around the globe.
    Keywords: QH301-705.5 ; QK1-989 ; Q1-390 ; n/a ; tree seedling recruitment ; shrubline ; light quality ; higher altitude ; precipitation ; experimental rain exclusion ; Pinus cembra ; Changbai Mountain ; treeline dynamics ; fungal ecology ; thermal continentality ; tree regeneration ; elevational transect ; monitoring ; conifer shrub ; plant water availability ; permafrost ; foehn winds ; treeline ; Holocene ; nitrogen cycling ; carotenoids ; timberline ; 15N natural abundance ; spectrometer ; basal area increment ; palynology ; xylem embolism ; diversity ; elevational treeline ; European Alps ; temperature ; tree line ; winter stress ; photosynthetic pigments ; Pinus sibirica ; westerly winds ; relative air humidity ; ecosystem manipulation ; Larix decidua ; microsite ; polar treeline ; Central Austrian Alps ; Switzerland ; multi-stemmed growth form ; conifers ; forest edge ; history of treeline research ; soil drought ; dendroclimatology ; knowledge engineering ; Rocky Mountains ; apical control ; cloud ; postglacial ; alpine timberline ; space-for-time substitution ; climate change ; expert elicitation ; shoot elongation ; pit aspiration ; climate warming ; climate zone ; alpine treeline ; refilling ; Abies sibirica ; growth trend ; western Montana ; light quantity ; Picea abies ; Mediterranean climate ; forest climatology ; altitude ; environmental stress ; sub-Antarctic ; Erman’s birch ; photoinhibition ; tocopherol ; elevational gradients ; NDVI ; long-term trends ; sap flow ; peat ; tree seedlings ; Southern Ocean ; chlorophyll ; non-structural carbohydrates (NSCs) ; drought ; upward advance ; remote sensing data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    The Ohio State University Press | The Ohio State University Press
    Publication Date: 2024-03-27
    Description: In Black Dragon, Zachary F. Price illuminates martial arts as a site of knowledge exchange between Black, Asian, and Asian American people and cultures to offer new insights into the relationships among these groups. Drawing on case studies that include Kareem Abdul-Jabbar’s appearance in Bruce Lee’s film Game of Death, Ron Van Clief and the Black Panther Party for Self-Defense, the Wu-Tang Clan, and Chinese American saxophonist Fred Ho, Price argues that the regular blending and borrowing between these distinct cultural heritages is healing rather than appropriative. His analyses of performance, power, and identity within this cultural fusion demonstrate how, historically, urban working-class Black men have developed community and practiced self-care through the contested adoption of Asian martial arts practice. By zeroing in on this rich but heretofore understudied vein of American cultural exchange, Price not only broadens the scholarship around sites of empowerment via such exchanges but also offers a compelling example of nonessentialist liberation for the twenty-first century.
    Keywords: Literary Criticism ; Drama ; Literary Criticism ; American ; Asian American ; Literary Criticism ; American ; African American & Black ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSG Literary studies: plays and playwrights ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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    Kriterium
    Publication Date: 2024-04-14
    Description: Nina Berberova (1901–1993) almost appears to have lived several lives. First, she was a young writer in the revolutionary Russia. Then she witnessed the hectic 1920s in Berlin and achieved her literary breakthrough in interwar Paris with psychologically finely-honed novels and short stories set in the Russian émigré community. Finally, she went on in the latter half of the century to a career as a Slavist in the United States. She had her eyes on Russia the whole time. As an academic she studied the cracks in the ideological wall and seems early on to have foreseen her return to her homeland. At last, as she approached the age of ninety, she had vanquished the Soviet Union and could go back in triumph in the “revolutionary” year of 1989. In addition to everything else Berberova was an avid letter writer who maintained a great many correspondences. For nearly thirty years she was friends with her Russian – and Petersburgian –countryman Sergej Rittenberg (1899–1975) in Stockholm, to whom she sent more than 150 letters and postcards between 1947 and 1975. A reflection of her thoughts and reading interests, they also provide a glimpse into the genesis of her huge memoir The Italics Are Mine (Kursiv moj). This volume presents Berberova’s letters with an introduction and extensive commentaries by Professor Magnus Ljunggren.
    Keywords: Russia ; Russian literature ; Sweden ; Nina Berberova ; thema EDItEUR::Y Children’s, Teenage and Educational::YP Educational material::YPC Educational: Language, literature and literacy::YPCA Educational: First / native language::YPCA9 Educational: First / native language: Literature studies::YPCA91 Educational: First / native language: School editions of literature texts ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DN Biography and non-fiction prose::DNL Literary essays ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general
    Language: English
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Cognitive processing is commonly conceptualized as being restricted to the cerebral cortex. Accordingly, electrophysiology, neuroimaging and lesion studies involving human and animal subjects have almost exclusively focused on defining roles for cerebral cortical areas in cognition. Roles for the thalamus in cognition have been largely ignored despite the fact that the extensive connectivity between the thalamus and cerebral cortex gives rise to a closely coupled thalamo-cortical system. However, in recent years, growing interest in the thalamus as much more than a passive sensory structure, as well as methodological advances such as high-resolution functional magnetic resonance imaging of the thalamus and improved electrode targeting to subregions of thalamic nuclei using electrical stimulation and diffusion tensor imaging, have fostered research into thalamic contributions to cognition. Evidence suggests that behavioral context modulates processing in primary sensory, or first-order, thalamic nuclei (for example, the lateral geniculate and ventral posterior nuclei), allowing attentional filtering of incoming sensory information at an early stage of brain processing. Behavioral context appears to more strongly influence higher-order thalamic nuclei (for example, the pulvinar and mediodorsal nucleus), which receive major input from the cortex rather than the sensory periphery. Such higher-order thalamic nuclei have been shown to regulate information transmission in frontal and higher-order sensory cortex according to cognitive demands. This Research Topic aims to bring together neuroscientists who study different parts of the thalamus, particularly thalamic nuclei other than the primary sensory relays, and highlight the thalamic contributions to attention, memory, reward processing, decision-making, and language. By doing so, an emphasis is also placed on neural mechanisms common to many, if not all, of these cognitive operations, such as thalamo-cortical interactions and modulatory influences from sources in the brainstem and basal ganglia. The overall view that emerges is that the thalamus is a vital node in brain networks supporting cognition.
    Keywords: RC321-571 ; Q1-390 ; neural synchrony ; cognitive control ; intralaminar thalamus ; mediodorsal thalamus ; Memory ; Pulvinar ; thalamocortical interactions ; oscillations ; anterior thalamus ; Prefrontal Cortex ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Johns Hopkins University Press
    Publication Date: 2024-03-26
    Description: Originally published in 1960. In E. E. Cummings: The Art of His Poetry, Norman Friedman argues that critics who have focused on what Cummings's poetry lacks have failed to judge Cummings on his strengths. Friedman identifies a main strength of Cummings as his being a "sensual mystic." The book unpacks Cummings's subject matter, devices, and symbolism, ultimately helping readers develop a deeper understanding and appreciation of Cummings's work.
    Keywords: Literature: history & criticism ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
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    Springer Nature | Palgrave Macmillan
    Publication Date: 2024-04-06
    Description: This open access book contributes to the discourse of Responsible Artificial Intelligence (AI) from an African perspective. It is a unique collection that brings together prominent AI scholars to discuss AI ethics from theoretical and practical African perspectives and makes a case for African values, interests, expectations and principles to underpin the design, development and deployment (DDD) of AI in Africa. The book is a first in that it pays attention to the socio-cultural contexts of Responsible AI that is sensitive to African cultures and societies. It makes an important contribution to the global AI ethics discourse that often neglects AI narratives from Africa despite growing evidence of DDD in many domains. Nine original contributions provide useful insights to advance the understanding and implementation of Responsible AI in Africa, including discussions on epistemic injustice of global AI ethics, opportunities and challenges, an examination of AI co-bots and chatbots in an African work space, gender and AI, a consideration of African philosophies such as Ubuntu in the application of AI, African AI policy, and a look towards a future of Responsible AI in Africa. This is an open access book.
    Keywords: Artificial Intelligence ; AI Ecosystems in Africa ; AI ethics ; digital culture ; SDGs ; Sustainable Development Goals ; AI policy ; ICT infrastructure in Africa ; AI governance ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RG Geography::RGC Human geography ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy
    Language: English
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    Sydney University Press
    Publication Date: 2024-03-26
    Description: Australia has been seen as a land of both punishment and refuge. Australian literature has explored these controlling alternatives, and vividly rendered the landscape on which they transpire. Twentieth-century writers left Australia to see the world; now Australia's distance no longer provides sanctuary. But today the global perspective has arrived with a vengeance. In Contemporary Australian Literature: A World Not Yet Dead, Nicholas Birns tells the story of how novelists, poets and critics, from Patrick White to Hannah Kent, from Alexis Wright to Christos Tsiolkas, responded to this condition. With rancour, concern and idealism, modern Australian literature conveys a tragic sense of the past yet an abiding vision of the way forward. Birns paints a vivid picture of a rich Australian literary voice - one not lost to the churning of global markets, but in fact given new life by it.
    Keywords: Literature ; Australian literature ; literary studies ; literary criticism ; Australian literary criticism ; literature and neoliberalism ; Australia ; Australian literature ; Neoliberalism ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Forests cover 30% of the Earth’s land area, or nearly four billion hectares. Enhancing the benefits and ecosystem services of forests has been increasingly recognized as an essential part of nature-based solutions for solving many emerging global environmental problems today. A core science supporting forest management is understanding the interactions of forests, water, and people. These interactions have become increasingly complex under climate change and its associated impacts, such as the increases in the intensity and frequency of drought and floods, increasing population and deforestation, and a rise in global demands for multiple ecosystem services including clean water supply and carbon sequestration. Forest watershed managers have recognized that water management is an essential component of forest management. Global environmental change is posing more challenges for managing forests and water toward sustainable development. New science on forest and water is critically needed across the globe. The International Forests and Water Conference 2018, Valdivia, Chile (http://forestsandwater2018.cl/), a joint effort of the 5th IUFRO International Conference on Forests and Water in a Changing Environment and the Second Latin American Conference on Forests and Water provided a unique forum to examine forest and water issues in Latin America under a global context. This book represents a collection of some of the peer-reviewed papers presented at the conference that were published in a Special Issue of Forests.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; social capital ; Cambodia ; forest and water policy ; land use and land cover change ; shrubland ; “Forests to Faucets” ; precipitation gradient ; forest ecosystem management ; afforestation ; connectivity ; land use change ; forest operations ; Chile ; catchment management ; forest plantation ; climate change ; compound wildfire-water risk ; native forest ; hydrology ; wetland ; streamside native buffer ; sustainability ; participatory monitoring ; hydrological modeling ; timber harvesting ; water quality ; native forests ; source water protection ; global change ; forest hydrology ; community drinking-water ; SDGs ; drinking-water security ; Oregon ; forest ; aquatic-riparian ecosystems ; NDC ; heat: moisture index ; watershed management ; load ; Rhyacotriton ; ecohydrology ; nutrient concentrations ; multi-criteria analysis ; Loess Plateau ; dissolved organic matter ; US Pacific Northwest ; soil moisture ; agricultural lands ; water management ; water provision ; water supply ; forests ; post-fire hydrology ; grassland ; forest plantations ; restoration strategy ; riparian buffer zones ; Mekong ; riparian vegetation ; density management harvest ; SWAT model ; forest watersheds ; water governance ; Nenjiang River ; forestry ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    De Gruyter | De Gruyter
    Publication Date: 2024-04-02
    Description: In a global context in which phenomena of migration play an ever more important role, the ways individual and collective experiences of migration are covered in the media, represented in culture, and interpreted are coming under increasing scrutiny. This book explores the complex relationship between creative engagements with migration on the one hand, and forms of knowledge about migration on the other, inquiring into the ways aesthetic practices are intertwined with knowledge structures. The book responds to three pressing research questions. First, it analyses how fictional texts, plays, images, films, and autobiographical accounts mediate forms of knowledge about migration. Second, it identifies the ways in which specific media approaches and aesthetic practices influence people’s ideas about and awareness of migratory experiences in a globalized world. Finally, it delineates how historical perspectives help us compare epistemological approaches to migration in the nineteenth, twentieth, and early twenty-first centuries, and how these approaches affect the way critics and the public responded to and thought about different forms of (forced) migration. Bringing together renowned scholars working across disciplines, it investigates the possibilities and limitations that different media present when it comes to reflecting on, communicating, and imagining experiences of migration, and how these representations in turn create ways of knowing and understanding migration. ; In a global context in which phenomena of migration play an ever more important role, the ways individual and collective experiences of migration are covered in the media, represented in culture, and interpreted are coming under increasing scrutiny. This book explores the complex relationship between creative engagements with migration on the one hand, and forms of knowledge about migration on the other, inquiring into the ways aesthetic practices are intertwined with knowledge structures. The book responds to three pressing research questions. First, it analyses how fictional texts, plays, images, films, and autobiographical accounts mediate forms of knowledge about migration. Second, it identifies the ways in which specific media approaches and aesthetic practices influence people’s ideas about and awareness of migratory experiences in a globalized world. Finally, it delineates how historical perspectives help us compare epistemological approaches to migration in the nineteenth, twentieth, and early twenty-first centuries, and how these approaches affect the way critics and the public responded to and thought about different forms of (forced) migration. Bringing together renowned scholars working across disciplines, it investigates the possibilities and limitations that different media present when it comes to reflecting on, communicating, and imagining experiences of migration, and how these representations in turn create ways of knowing and understanding migration.
    Keywords: Globalisierung ; Visuelle Künste ; Diaspora ; Literaturwissenschaft ; Kulturwissenschaft ; Globalization ; literary and cultural studies ; visual arts ; thema EDItEUR::A The Arts::AJ Photography and photographs ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-04
    Description: An important, open research topic today is to understand the relevance that dark matter halo substructure may have for dark matter searches. In the standard cosmological model, halo substructure or subhalos are predicted to be largely abundant inside larger halos, for example, galaxies such as ours, and are thought to form first and later merge to form larger structures. Dwarf satellite galaxies—the most massive exponents of halo substructure in our own galaxy—are already known to be excellent targets for dark matter searches, and indeed, they are constantly scrutinized by current gamma-ray experiments in the search for dark matter signals. Lighter subhalos not massive enough to have a visible counterpart of stars and gas may be good targets as well, given their typical abundances and distances. In addition, the clumpy distribution of subhalos residing in larger halos may boost the dark matter signals considerably. In an era in which gamma-ray experiments possess, for the first time, the exciting potential to put to test the preferred dark matter particle theories, a profound knowledge of dark matter astrophysical targets and scenarios is mandatory should we aim for accurate predictions of dark matter-induced fluxes for investing significant telescope observing time on selected targets and for deriving robust conclusions from our dark matter search efforts. In this regard, a precise characterization of the statistical and structural properties of subhalos becomes critical. In this Special Issue, we aim to summarize where we stand today on our knowledge of the different aspects of the dark matter halo substructure; to identify what are the remaining big questions, and how we could address these; and, by doing so, to find new avenues for research.
    Keywords: QB1-991 ; Q1-390 ; QC1-999 ; gamma rays ; indirect searches. ; semi-analytic modeling ; cosmological model ; indirect dark matter searches ; particle dark matter ; indirect detection ; gamma-rays and neutrinos ; galactic subhalos ; indirect searches ; statistical data analysis ; subhalo boost ; dark matter halos ; halo substructure ; structure formation ; dark matter annihilation ; dark matter searches ; dwarf spheroidal satellite galaxies ; galactic sub-halos ; subhalos ; dwarf spheroidal galaxies ; gamma-rays ; cosmological N-body simulations ; dark matter ; thema EDItEUR::P Mathematics and Science::PG Astronomy, space and time
    Language: English
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  • 97
    Publication Date: 2024-04-14
    Description: Leading publishers and observers of the science publishing scene comment in essay form on key developments over the past century. The scale of the global research effort and its industrial organisation have resulted in substantial increases in the published volume, as well as new techniques for its handling. The former languages of science communication, like Latin and German, have given way to English. The domination of European science before WWII has been followed by large efforts in North America and the Far East. The roots of the National Library of Medicine lie in the US Army medical library, the US War effort gave rise to hypertext, and the US defense reaction to the Soviet Sputnik resulted in the Internet. The European invention of the Web has also changed the science publishing scene in the past five years. Some characteristic publishing enterprises, commercial and society owned, are described in a series of articles. These are followed by analysis of recent developments and possible changes to come. Functions of publishers, librarians and agents are brought into context. The future of publishing is currently being debated on open channels, while the historical dimension and professional input are sometimes lacking.
    Keywords: Z ; Q1-390 ; 20th century ; science ; ICT ; publishing ; thema EDItEUR::U Computing and Information Technology
    Language: English
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  • 98
    Publication Date: 2024-04-05
    Description: Music is an important source of enjoyment, learning, and well-being in life as well as a rich, powerful, and versatile stimulus for the brain. With the advance of modern neuroimaging techniques during the past decades, we are now beginning to understand better what goes on in the healthy brain when we hear, play, think, and feel music and how the structure and function of the brain can change as a result of musical training and expertise. For more than a century, music has also been studied in the field of neurology where the focus has mostly been on musical deficits and symptoms caused by neurological illness (e.g., amusia, musicogenic epilepsy) or on occupational diseases of professional musicians (e.g., focal dystonia, hearing loss). Recently, however, there has been increasing interest and progress also in adopting music as a therapeutic tool in neurological rehabilitation, and many novel music-based rehabilitation methods have been developed to facilitate motor, cognitive, emotional, and social functioning of infants, children and adults suffering from a debilitating neurological illness or disorder. Traditionally, the fields of music neuroscience and music therapy have progressed rather independently, but they are now beginning to integrate and merge in clinical neurology, providing novel and important information about how music is processed in the damaged or abnormal brain, how structural and functional recovery of the brain can be enhanced by music-based rehabilitation methods, and what neural mechanisms underlie the therapeutic effects of music. Ideally, this information can be used to better understand how and why music works in rehabilitation and to develop more effective music-based applications that can be targeted and tailored towards individual rehabilitation needs. The aim of this Research Topic is to bring together research across multiple disciplines with a special focus on music, brain, and neurological rehabilitation. We encourage researchers working in the field to submit a paper presenting either original empirical research, novel theoretical or conceptual perspectives, a review, or methodological advances related to following two core topics: 1) how are musical skills and attributes (e.g., perceiving music, experiencing music emotionally, playing or singing) affected by a developmental or acquired neurological illness or disorder (for example, stroke, aphasia, brain injury, Alzheimer’s disease, Parkinson’s disease, autism, ADHD, dyslexia, focal dystonia, or tinnitus) and 2) what is the applicability, effectiveness, and mechanisms of music-based rehabilitation methods for persons with a neurological illness or disorder? Research methodology can include behavioural, physiological and/or neuroimaging techniques, and studies can be either clinical group studies or case studies (studies of healthy subjects are applicable only if their findings have clear clinical implications).
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; Brain ; Movement ; Music ; neurological disorders ; Cognition ; Rehabilitation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 99
    Publication Date: 2023-12-20
    Description: Emergent quantum mechanics explores the possibility of an ontology for quantum mechanics. The resurgence of interest in ""deeper-level"" theories for quantum phenomena challenges the standard, textbook interpretation. The book presents expert views that critically evaluate the significance—for 21st century physics—of ontological quantum mechanics, an approach that David Bohm helped pioneer. The possibility of a deterministic quantum theory was first introduced with the original de Broglie-Bohm theory, which has also been developed as Bohmian mechanics. The wide range of perspectives that were contributed to this book on the occasion of David Bohm’s centennial celebration provide ample evidence for the physical consistency of ontological quantum mechanics. The book addresses deeper-level questions such as the following: Is reality intrinsically random or fundamentally interconnected? Is the universe local or nonlocal? Might a radically new conception of reality include a form of quantum causality or quantum ontology? What is the role of the experimenter agent? As the book demonstrates, the advancement of ‘quantum ontology’—as a scientific concept—marks a clear break with classical reality. The search for quantum reality entails unconventional causal structures and non-classical ontology, which can be fully consistent with the known record of quantum observations in the laboratory.
    Keywords: Q1-390 ; QC1-999 ; non-locality ; ultraviolet divergence ; constraints ; Kilmister equation ; bohmian mechanics ; epistemic agent ; Bohmian mechanics ; relational space ; Feynman paths ; Langevin equation ; quantum causality ; emergent quantum gravity ; quantum ontology ; interpretations ; emergent quantum state ; undecidable dynamics ; molecule interference ; emergent quantum mechanics ; no-hidden-variables theorems ; mind–body problem ; physical ontology ; quantum foundations ; matter-wave optics ; conscious agent ; diffusion constant ; Bell theorem ; Burgers equation ; objective non-signaling constraint ; self-referential dynamics ; Bell inequality ; interpretation ; photochemistry ; Born rule statistics ; sub-quantum dynamics ; dynamical chaos ; weak measurement ; p-adic metric ; Levi-Civita connection ; David Bohm ; H-theorem ; the causal arrow of time ; strong coupling ; vortical dynamics ; fundamental irreversibility ; magnetic deflectometry ; quantum thermodynamics ; de Broglie–Bohm interpretation of quantum mechanics ; wavefunction nodes ; stochastic quantum dynamics ; entropic gravity ; metrology ; Schrödinger equation ; gauge freedom ; Monte Carlo simulations ; micro-constituents ; nonequilibrium thermodynamics ; Bell’s theorem ; emergent space-time ; spin ; quantum field theory ; time-symmetry ; Gaussian-like solutions ; Hamiltonian ; number theory ; fractional velocity ; ergodicity ; fractal geometry ; atomic metastable states ; operator thermodynamic functions ; Canonical Presentation ; Retrocausation ; interpretations of quantum mechanics ; Bohm theory ; quantum mechanics ; zero-point field ; conspiracy ; pilot wave ; quantum holism ; toy-models ; curvature tensor ; Aharonov–Bohm effect ; computational irreducibility ; Stochastic Electrodynamics ; diffraction ; retrocausality ; resonances in quantum systems ; stochastic differential equations ; Bianchi identity ; past of the photon ; commutator ; relational interpretation of quantum mechanics ; free will ; nomology ; trajectories ; primitive ontology ; Mach–Zehnder interferometer ; weak values ; singular limit ; interior-boundary condition ; Poincaré recurrence ; quantum inaccessibility ; symplectic camel ; surrealistic trajectories ; observables ; Stern-Gerlach ; decoherence ; quantum non-equilibrium ; generalized Lagrangian paths ; superdeterminism ; black hole thermodynamics ; nonlocality ; measurement problem ; entropy and time evolution ; bouncing oil droplets ; spontaneous state reduction ; quantum theory ; many interacting worlds ; complex entropy. ; Turing incomputability ; iterant ; space-time fluctuations ; quantum potential ; ontological quantum mechanics ; photon trajectory ; Dove prism ; the Friedrichs model ; contextuality ; discrete calculus ; transition probability amplitude ; gravity ; pilot-wave theory ; matter-waves ; de Broglie-Bohm theory ; covariant quantum gravity ; atom-surface scattering ; de Broglie–Bohm theory ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 100
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    Taylor & Francis | Storytelling and Ethics | Routledge
    Publication Date: 2024-03-26
    Description: In recent years there has been a huge amount of both popular and academic interest in storytelling as something that is an essential part of not only literature and art but also our everyday lives as well as our dreams, fantasies, aspirations, historical self-understanding, and political actions. The question of the ethics of storytelling always, inevitably, lurks behind these discussions, though most frequently it remains implicit rather than explicit. This volume explores the ethical potential and risks of storytelling from an interdisciplinary perspective. It stages a dialogue between contemporary literature and visual arts across media (film, photography, performative arts), interdisciplinary theoretical perspectives (debates in narrative studies, trauma studies, cultural memory studies, ethical criticism), and history (traumatic histories of violence, cultural history). The collection analyses ethical issues involved in different strategies employed in literature and art to narrate experiences that resist telling and imagining, such as traumatic historical events, including war and political conflicts. The chapters explore the multiple ways in which the ethics of storytelling relates to the contemporary arts as they work with, draw on, and contribute to historical imagination. The book foregrounds the connection between remembering and imagining and explores the ambiguous role of narrative in the configuration of selves, communities, and the relation to the non-human. While discussing the ethical aspects of storytelling, it also reflects on the relevance of artistic storytelling practices for our understanding of ethics. Making an original contribution to interdisciplinary narrative studies and narrative ethics, this book both articulates a complex understanding of how artistic storytelling practices enable critical distance from culturally dominant narrative practices, and analyzes the limitations and potential pitfalls of storytelling.
    Keywords: Storytelling; ethics; Hanna Meretoja ; thema EDItEUR::D Biography, Literature and Literary studies::D Biography, Literature and Literary studies::DS Literature: history and criticism ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy
    Language: English
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