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  • Plant Physiology.  (108)
  • Medicine Research.  (101)
  • Singapore :Springer Nature Singapore :  (209)
  • American Chemical Society (ACS)
  • Blackwell Publishing Ltd
  • MDPI Publishing
  • English  (209)
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  • English  (209)
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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Metabolism Disorders. ; Genetics. ; Cardiovascular system. ; Physiology. ; Biomedical Research. ; Metabolic Disease. ; Genetics and Genomics. ; Cardiovascular Physiology.
    Description / Table of Contents: An overview of genome editing in cardiovascular and metabolic diseases -- Bioinformatics research methodology of genome editing in cardiovascular and metabolic diseases -- Online databases of genome editing in cardiovascular and metabolic diseases -- Application of systems biology for genome editing involved in regulating of cardiovascular and metabolic diseases -- Bioinformatics for reducing off-targets in cardiovascular and metabolic diseases -- Genome editing and cardiac regeneration -- Genome editing and myocardial development -- Genome editing and heart failure -- Genome editing and pathological cardiac hypertrophy -- Genome editing and cardiac remodeling -- Genome editing and diabetic cardiomyopathy -- Genome editing and cardiac arrhythmias -- Genome editing and atrial fibrillation -- Genome editing and muscle atrophy -- Genome editing and obesity -- Genome editing and fatty liver -- Genome editing and diabetes -- Genome editing and gout -- Genome editing and protein energy malnutrition -- Genome therapy and cardiovascular diseases -- Therapeutics in metabolic diseases -- Gene editing and human iPSCs in cardiovascular and editing diseases -- Prospective advances in genome editing investigation.
    Abstract: This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.
    Type of Medium: Online Resource
    Pages: XII, 339 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811956423
    Series Statement: Advances in Experimental Medicine and Biology, 1396
    DDC: 610.72
    Language: English
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  • 2
    Keywords: Stress (Physiology). ; Plants. ; Plant physiology. ; Botanical chemistry. ; Metabolism, Secondary. ; Plant Stress Responses. ; Plant Physiology. ; Plant Biochemistry. ; Plant Secondary Metabolism.
    Description / Table of Contents: Chapter 1:An Update on Reactive Oxygen Species Synthesis and its Potential Application -- Chapter 2 :Mechanism of Reactive Oxygen Species Regulation in Plants -- Chapter 3: Biomolecules Targeted by Reactive Oxygen Species -- Chapter 4: Functions of Reactive Oxygen Species in Improving Agriculture and Future Crop Safety -- Chapter 5: The Ecology of Reactive Oxygen Species Signaling -- Chapter 6: Physiological Impact of Reactive Oxygen Species on Leaf -- Chapter 7: Reactive Oxygen Species: Role in Senescence and Signal Transduction -- Chapter 8: Hazardous Phytotoxic Nature of Reactive Oxygen Species in Agriculture -- Chapter 9: Hormonal Response in Plants Influenced by Reactive Oxygen Species -- Chapter 10: The Dual Role of Reactive Oxygen Species as Signals that Influence Plant Stress Tolerance and Programmed Cell Death -- Chapter 11: ight into the Interaction of Strigolactones, Abscisic Acid, and Reactive Oxygen Species Signals -- Chapter 12: 12. Hydrogen Peroxide: Regulator of Plant Development and Abiotic Stress Response -- Chapter 13:Towards Sustainable Agriculture: Strategies Involving Phyto-Protectants against Reactive Oxygen Species -- chapter 14:Signaling Pathway of Reactive Oxygen Species in Crop Plants under Abiotic Stress -- Chapter 15: Adverse Impact of ROS on Nutrient Accumulation and Distribution in Plants.
    Abstract: This edited book focuses on ROS synthesis, potential applications, toxicity, and preservations. It explores the recently proposed hormonal response and biomolecules targeted in regulation of ROS. Chapters cover resistance and susceptibility to plant pathogen, strategies involving phytoprotectants, and life span of nematode affected by ROS. This book includes a compilation of recently written, integrated, and illustrated reviews describing latest information on ROS. Chapters incorporate both theoretical and practical aspects of plant ROS. Reactive oxygen species (ROS) are key signaling molecules involved in the redox equilibrium and biological processes. In plants, ROS play an important role in biotic and abiotic stress sensing, integration of diverse environmental signals, and commencement of stress-response networks, thus contributing to the establishment of defense mechanisms and plant resilience. Critical amount of ROS is required by plants for regular operation of vital physiological mechanisms. This book brings together a compilation of latest research work on reactive oxygen species and their emerging importance. The book is a useful read for students, researchers, and scientists in the field of agri-life sciences.
    Type of Medium: Online Resource
    Pages: XIII, 295 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811997945
    DDC: 581.788
    Language: English
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  • 3
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biomedical Research. ; Cell Biology.
    Description / Table of Contents: Chapter 1. Magnetic Field Parameters and Biological Sample Differences that Lead to Differential Bioeffects -- Chapter 2. Static Magnetic Field Direction-induced Differential Biological Effects -- Chapter 3. Magnetic Properties of Biological Samples -- Chapter 4. Molecular Mechanisms for Electromagnetic Field Biosensing -- Chapter 5. Controlling Cell Membrane Potential with Static Non-uniform Magnetic Fields -- Chapter 6. Impact of Static Magnetic Fields on Cells -- Chapter 7. Impact of Static Magnetic Fields on Microorganisms, Plants and Animals -- Chapter 8. Static Magnetic Fields on Human Bodies -- Chapter 9. Potential Applications of Static Magnetic Fields in Cancer Treatment -- Chapter 10. Effects of Static Magnetic Fields on Diabetes and Its Complications -- Chapter 11. Impacts of Static Magnetic Field on Bone Health -- Chapter 12. Effects of Static Magnetic Fields on the Immune System -- Chapter 13. Biological Effects of Static Magnetic Fields on the Nervous System -- Chapter 14. The Biological Effects of Long-term Static Magnetic Field Exposure -- Chapter 15. Prospects, Pitfalls, and Opportunities for Human Static Magnetic Field Therapy.
    Abstract: The book summarizes the emerging topic about the effects of SMF on biological samples ranging from single molecules, subcellular compartments, and cells to whole organisms. It also discusses the potential application of SMF in clinical treatment of cancer, pain, diabetes and other diseases. With the development and growing popularity of modern appliances like MRI in hospitals, the potential impact of magnetic fields on human health is invoking increasing concerns. At the same time, SMF has been explored in the treatment of tumor and other diseases for decades. Nevertheless, there are still some reservations and uncertainties about these treatments, which are largely due to the differential biological effects reported in the literature. These experimental inconsistencies are mainly caused by variations such as different magnetic field types, intensities, treatment time, as well as biological samples examined. The second edition added eight new chapters about new progress in this field including impacts of SMFs, magnetism of biomolecules, and potential of SMFs in the management of bone, pain, diabetes, and immune systems. This volume will help clarify some dilemmas in this field and encourage further investigations in order to achieve a better understanding of the biological effects of SMF, aiming for a rational application of SMF in clinical therapy in the near future. The book is useful for scientists, doctors, and students who are interested in magnetic fields and life sciences.
    Type of Medium: Online Resource
    Pages: XV, 420 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811988691
    DDC: 610.72
    Language: English
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  • 4
    Keywords: Agricultural biotechnology. ; Medicine Research. ; Biology Research. ; Materials. ; Detectors. ; Biomaterials. ; Agricultural Biotechnology. ; Biomedical Research. ; Sensors and biosensors. ; Biomaterials.
    Description / Table of Contents: Part – I Introduction -- Biomaterials and Biopolymers for the Development of Biosensors -- Part – II Development of nanomaterials and biocomposites as sensors -- Nanobiohybrid Materials for Development of Biosensors -- Biosynthesis, Biofunctionalization, and Bioapplications of Manganese Nanomaterials: An Overview -- Transducers in Biosensors -- Self-Assembly and Fabrication of Biomaterials onto Transducers and their Characterization -- Biocatalytic Sensors: Potentials, Maxims and Mechanisms for Optimal Performance -- Part – III Potential role and applications of bio-based sensors -- Polyhydroxyalkanoate-based sensors and their applications -- An Overview of Immunosensors and their Application -- Live Cells as Biosensors -- Part – IV Biomaterials-based sensors for agricultural and biomedical applications -- Magnetic Nanoparticles Based Novel Sensors for select biomedical/ biological science applications -- Electrochemical Biosensors in Agricultural and Veterinary Applications -- The Applications of Biosensors and Biochips for Prognosis and Diagnosis of Diseases.
    Abstract: With the recent technological advancement usage of unique nanomaterials and bio-based composite materials as sensors has been greatly improved. Biopolymers and bio-based composite materials have especially been exploited due to their unique physical, optical, electrochemical, and biocompatible properties. In this book, experts and researchers in various sensor technology areas discuss the basics of biosensors, the methods used to synthesize different biomaterials, and the characterization and functionalization of these biomaterials. Processes for the self-assembly of biomaterials and the fabrication of biomaterials onto transducers are clearly explained. It also outlines the current status in the field and the utility of such bio-based sensors for medical diagnostics, food safety, industrial, and environmental monitoring. Besides pressure and temperature sensing applications, other applications include detecting gases, chemicals, biomolecules, body fluids, bacteria, and viruses. The book is well illustrated, and the presentation is concise and systematic throughout. Biomaterials-Based Sensors will be an ideal source of up-to-date information for all engaged in their research, design, and use.
    Type of Medium: Online Resource
    Pages: XV, 411 p. 110 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811985010
    DDC: 630
    Language: English
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  • 5
    Keywords: Medicine Research. ; Biology Research. ; Biology. ; Neurosciences. ; Biotechnology. ; Drug delivery systems. ; Biomedical Research. ; Biological Sciences. ; Neuroscience. ; Biotechnology. ; Drug Delivery.
    Description / Table of Contents: Chapter 1.Deciphering New Drug Targets in Alzheimer’s Disease -- Chapter 2. Novel Therapeutic Targets for Treating Alzheimer’s Disease -- Chapter 3. Modified Investigation Tools and Techniques Useful in Alzheimer’s Disease Research -- Chapter 4. Dual Specificity Tyrosine Phosphorylation Regulated Kinase1A (DYRK1A) Inhibitors: The Quest for a Disease-Modifying Treatment for Alzheimer’s Disease -- Chapter 5. β-secretase as a primary drug target of Alzheimer disease: Function, Structure, and Inhibition -- Chapter 6. Endocrine Receptors: The Potential Therapeutic Targets for Alzheimer’s -- Chapter 7. Calcium Channels as a Potential Therapeutic Target for Alzheimer’s Disease -- Chapter 8. Traversing Through the Trajectory of Pathogenic Astrocytes in Alzheimer’s Disease -- Chapter 9. Targeting Mitochondrial Dynamics as a Restorative Approach in the Treatment of Alzheimer’s Disease -- Chapter 10. Epigenetic Therapy for Alzheimer’s Disease -- Chapter 11. Exploring the Diverse Roles of GSK-3ß Kinase in Alzheimer’s Disease -- Chapter 12. Role of Target Fishing in Discovery of Novel Anti-Alzheimer’s Agents: In Silico Applications -- Chapter 13. Multi-Target Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery -- Chapter 14. Investigating the Role of Tau Proteins in Alzheimer’s Disease-From Typical Functioning MAPs to Aberrant Fibrillary Deposits in the Brain -- Chapter 15. The Overview of Drugs Used in Alzheimer’s Disease and Their Molecular Targets.
    Abstract: This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.
    Type of Medium: Online Resource
    Pages: XV, 381 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819926572
    DDC: 610.72
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Life sciences. ; Cytology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Life Sciences. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: Part I. Search for novel tumor epitopes related to carbohydrates -- Chapter 1.1. The ganglioside structures: chemistry and biochemistry -- Chapter 1.2. Fucosylated proteins as cancer biomarkers -- Part II. Assembly of glycoconjugates -- Chapter 2.1. Siglec-7 and synthetic sialylpolymer -- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis -- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer -- Part III. Signaling pathways modulated by glycosylation -- Chapter 3.1. Significance of FUT8in pancreatic cancer and others -- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells -- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules -- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells -- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction -- Part V. Clinical trials targeting glycosignals -- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.
    Abstract: This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
    Type of Medium: Online Resource
    Pages: VI, 238 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811977329
    DDC: 610.72
    Language: English
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  • 7
    Keywords: Agriculture. ; Agronomy. ; Soil science. ; Plant physiology. ; Microbiology. ; Agriculture. ; Agronomy. ; Soil Science. ; Plant Physiology. ; Microbiology.
    Description / Table of Contents: Chapter 1 -- Plant-microbe interactions promoting millets plant growth and health: Perspectives for use of microorganisms in millets production, Chapter 2 -- Diversity and function of microbes associated with the rhizosphere of millets, Chapter 3 -- Biodiversity of arbuscular mycorrhizal fungi and its impact on millets growth, Chapter 4 -- Drought-tolerant plant growth-promoting rhizobacteria associated with millets, Chapter 5 -- Identification of novel microbial strain for reduced pesticide use in millets, Chapter 6 -- Current insights into the role of rhizosphere bacteria in disease suppression in millets, Chapter 7 -- Comparison of rhizospheric functional diversity between chemically fertilized and bioinoculated millet, Chapter 8 -- Deciphering the role and diversity of microbes present in millet rhizosphere, Chapter 9 -- Role of phosphate solubilizing microbes on phosphorous availability and yield attributes of millet, Chapter 10 -- Impact of rhizosphere ecology on nitrogen fixation in millets, Chapter 11 -- Synergistic effects of arbuscular mycorrhizal fungi and PGPR on yield improvements in millets, Chapter 13 -- Understanding of belowground biochemical communication in millets through metabolomics, Chapter 14 -- Prospects of gene editing techniques in manipulating the rhizosphere microbiome for millets productivity, Chapter 15 -- Effect of nano-formulated agrochemicals on rhizospheric communities in millets, Chapter 16 -- Potential application of nanotechnology in biofertilizer formulation for millets.
    Abstract: This edited volume is the first book that explicitly explains the link between the extraordinarily small-scale microbial processes and the growth and yield attributes of millet crops. This book includes chapters emphasizing on the effects of rhizosphere biology on long-term millet crop management. Millets are a collection of small-grained cereal grasses that are grown for human carbohydrate needs. They are among the oldest crops, mainly divided into two groups: major and small millets based on seed size. Major millets are composed of sorghum (Sorghum bicolor) and pearl millet (Pennisetum glaucum); while small millets are composed of six species that includes finger millet (Eleusine coracana (L.)), little millet (Panicum sumatrense), kodo millet (Paspalum scrobiculatum (L.)), foxtail millet (Setaria italica (L.)), barnyard millet (Echinochloa frumentacea (L.)), and proso millet (Panicum miliaceum (L.). These crops are earlier considered as orphan crops, but recently due to their nutritional values it is gaining the importance. Various reports are published based on role of rhizosphere on growth and health of these crops. The rhizosphere being a dynamic interface among the plant roots and soil microbes provides a number of advantages to the millets too. The soil properties in rhizospheric region are also different as compared to the bulk soil. This book discovers the functional attributes of rhizosphere in promoting the healthy growth of millet crop and achieving higher yield during the changing climatic condition. This book is of interest to university teachers, scientists working in the millets, and policymakers in agricultural departments. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, biotechnology, microbiology, genetics, and soil science.
    Type of Medium: Online Resource
    Pages: XIII, 348 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819921669
    Series Statement: Rhizosphere Biology,
    DDC: 630
    Language: English
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  • 8
    Keywords: Medicine Research. ; Biology Research. ; Forensic sciences. ; Medical jurisprudence. ; Biomedical Research. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Module 1_Introduction to Forensic Science & Crime -- Module 2_Criminalistics -- Module 3_ Forensic Biological Sciences -- Module 4_Forensic Physical Sciences -- Module 5_Forensic Chemical Sciences -- Module 6_Emerging fields in Trends in Forensics.
    Abstract: This textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tears, sweat, vaginal fluids, urine, and sweat. It also provides an overview of forensic examination of different types of evidence and also includes comprehensive detailing of forensic ballistics including firearm classification, bullet comparison and matching. Further, it explores the examinations of drugs, chemicals, explosives, and petroleum products. It focuses on the various aspects of forensic toxicology, including the study of various poisons/toxins, associated signs and symptoms, a fatal dose /fatal period of poisons. The book also emphasizes digital and cyber forensics, including classification, data recovery tools, encryption and decryption methods, image, and video forensics. It is a useful resource for graduate and post-graduate students in the field of Forensic Science.
    Type of Medium: Online Resource
    Pages: XV, 839 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819913770
    DDC: 610.72
    Language: English
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  • 9
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Plant physiology. ; Plant diseases. ; Plant Science. ; Plant Physiology. ; Plant Pathology.
    Description / Table of Contents: Chapter 1 -- Root-knot Nematodes (Meloidogyne spp.), Chapter 2 -- Meloidogyne species: Threat to Vegetable Produce, Chapter 3 -- hemotaxis in Root-Knot Nematodes, Chapter 4 -- Phytohormone-Mediated Feeding Site Development, Chapter 5 -- 5. Current and Future Studies on the Genes for Parasitism in Meloidogyne, Chapter 6 -- Natural Product Repertoire for Suppressing the Immune Response of Meloidogyne species, Chapter 7 -- Epigenetic Mechanisms and their Role in Root Gall Formation,Chapter 8 -- Mass Spectrometry Imaging (MSI) and Root Gall Elucidation, Chapter 9 -- 9. Root-Knot Disease Complex: An Interactive Perspective with Microorganisms, Chapter 10 -- Breeding for Resistance in Vegetables against Meloidogyne species causing Root Gall Disease, Chapter 11 -- An Overview of Predacious Fungi for the Management of Root-knot Disease in Vegetables, Chapter 12 -- Biofertilizer of Organic Origin for Management of Root Galling Disease of Vegetables, Chapter 13 -- Prospects for the Use of Metabolomics Engineering in Exploring and Harnessing Chemical Signalling in Root Galls.
    Abstract: This book provides the most comprehensive and up-to-date review of research on vegetable plants associated with root-galls disease caused by root-knot nematodes (RKNs), Meloidogyne spp. Vegetables retain a key position in cultural cuisines and their consumption worldwide due to rich sources of micronutrients, including vitamins, minerals and antioxidants, but root galls disease of these crops caused by RKNs steals both quantity and quality from production. The field of plant nematology has experienced exponential growth over the past decade, and these RKNs are now known as widely damaging obligate plant parasites of vegetable plants. Advances are being made in understanding their biology, parasitism in the root system, giant cell development, root gall formation, chemical signalling, root-knot disease complexes, and management systems. This compilation provides an invaluable resource for studying root-galls disease of vegetable plants to those readers associated with plant nematology, plant pathology, plant protection, and agricultural science, including researchers, teachers, advanced undergraduates and graduate students, and even agricultural extension agents and farmers.
    Type of Medium: Online Resource
    Pages: XIX, 338 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938926
    DDC: 580
    Language: English
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  • 10
    Keywords: Medicine Research. ; Biology Research. ; Regenerative medicine. ; Biomaterials. ; Biomedical Research. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials.
    Description / Table of Contents: Chapter 1. An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells -- Part I. Structural Scaffolds and Bio-activation -- Chapter 2. Polymeric and Biomimetic ECM Scaffolds for Tissue Engineering Applications -- Chapter 3. Versatile Hydrogels in Regenerative Medicine -- Chapter 4. Multilayer Microcapsules with Tailored Structures and Properties as Delivery Carriers for Drugs and Growth Factors -- Part II Biomaterials Surfaces/Interfaces and Bio-interactions. Chapter 5. Interactions of Biomaterial Surfaces with Proteins and Cells -- Chapter 6. Surface Modification of Tissue Engineering Scaffolds -- Chapter 7. Gradient Biomaterials and Their Impact on Cell Migration -- Chapter 8. Stem Cell Differentiation Mediated by Biomaterials/Surfaces -- Part III Regeneration of Some Clinic-Targeted Tissues -- Chapter 9. Cartilage Regeneration -- Chapter 10. Skin Regeneration -- Chapter 11. Regeneration of Blood Vessels -- Chapter 12. Cardiac repair and regeneration -- Chapter 13. Nerve Regeneration.
    Abstract: This book reviews state of the art of polymeric biomaterials for regenerative medicine and highlights advances in both fundamental science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physiochemical property modulation, as well as their influence on the adhesion and performance of biomolecules, cells, and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies. In the second edition, most of the chapters are updated according to the latest progress of this research field. A new chapter on nerve regeneration is also included.
    Type of Medium: Online Resource
    Pages: VIII, 577 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789819969487
    DDC: 610.72
    Language: English
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  • 11
    Keywords: Plant diseases. ; Stress (Physiology). ; Plants. ; Plant physiology. ; Plant Pathology. ; Plant Stress Responses. ; Plant Physiology.
    Description / Table of Contents: 1. Plant-pathogen interactions studies: Combinatorial approach and multidisciplinary benefits -- 2. Plant-pathogen interactions and global food security -- 3. Fusarium wilt of tomato: past, present, and future -- 4. Late Wilt of Maize—The Pathogen, the Disease, Current Status, and Future Perspective -- 5. Insights into grapevine defence response against fungal and oomycete diseases towards a sustainable plant breeding -- 6. Defensive Strategies of ROS in Plant-Pathogen Interactions -- 7. Phytohormone signaling and Plant-Pathogen Interaction -- 8. Quorum Sensing and its Role in Bacterial Pathogenicity -- 9. Pathobiome and Microbial Community Shifts Associated with Vegetable, Fruit and Cereal Crops -- 10. Prevalence of microbiome reservoirs in plants and pathogen outbreaks -- 11.Exploring Plant-Pathogen Interactions through Subcellular Proteomics -- 12. Genome Editing and Plant-Pathogen Interaction -- 13. Secreted effectors: a perspective in plant-fungus interaction.
    Abstract: This book covers all aspects of naturally occurring phenomenon of Plant-Pathogen Interaction (PPI). Recent findings and scientific explanations to understand PPI are provided accompanied by numerous helpful photographs and pictorial presentations. In addition, tabulated data is also included to aid in getting insight into the subject and identifying the missing links. Essential information is provided on physiological, biochemical and pathology consequences of PPI and distinguished sections are devoted to explain molecular and regulatory mechanism underlying PPI. Further topics include different classes of plant pathogen, receptor molecules, signaling system, secondary metabolism and plant defense system etc. This book helps the readers in understanding the state of art and emerging technics to explore PPI and in identifying the missing links which further help in creating the background for future exploration of PPI in terms of experimental and technical advancements. .
    Type of Medium: Online Resource
    Pages: XV, 362 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819948901
    DDC: 571.92
    Language: English
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  • 12
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Regenerative medicine. ; Medicine Research. ; Biology Research. ; Genetics. ; Epigenetics. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Research. ; Genetics. ; Epigenetics.
    Description / Table of Contents: Chapter 1. Genetics and Epigenetics of Ageing and Age Associated Diseases -- Chapter 2. Coenzyme Q as an anti aging strategy -- Chapter 3. Autophagy as a Promising Therapeutic Target in Age-Associated Neurodegenerative Disorders -- Chapter 4. Glycolytic inhibitors as Caloric Restriction Mimetics (CRM) -- Chapter 5. Anti-aging and rejuvenation based on stem cell therapy -- Chapter 6. Novel strategies for metformin as an anti-aging drug in skin aging -- Chapter 7. Anti-inflammatory-dependent anti-aging strategies -- Chapter 8. Spermidine, an autophagy inducer, as a therapeutic anti-aging strategy -- Chapter 9. Melatonin in Aging and Aging Related Disorders -- Chapter 10. Intermittent fasting as an anti- aging strategy -- Chapter 11. The role of curcumin as an anti-aging compound -- Chapter 12. The Role of Telomerase Activators in Anti-Aging Strategies and Their Clinical Potential -- Chapter 13. Clinical Laboratories and Their Role in Anti-Aging Strategies -- Chapter 14. Antiaging strategies based on sirtuin activation -- Chapter 15. A vaccine for the pandemic of ageing? Conceptual and ethical issues -- Chapter 16. Cognitive and emotional ageing across the life span: Implications for building the cognitive reserve and resilience -- Chapter 17. Tissue reconstructive & regenerative medicine approach as an anti-ageing intervention: Relevance to age-induced Osteoarthritis -- Chapter 18. Age-Adjustment Expertise in Animal Models of Human Diseases.
    Abstract: The book focuses on the emerging anti-aging approaches for maintaining better health in old age. It provides a current understanding of the underlying principle, possible targets, implementation approaches, and efficacy of the various anti-aging strategies. The chapters include a wide range of topics incorporating the major advances in anti-aging strategies, including telomerase activation, stem cell therapy, autophagy induction, sirtuin activation, and dietary restrictions. Further, it discusses the epigenetic mechanisms underlying aging-related processes and epigenetic strategies to delay and reverse aging-related diseases. The book covers the strategy based on tissue engineering and regenerative medicine for understanding the complexity of aging and restoring the functionalities of organ systems. It further presents the applications of melatonin supplementation-based anti-aging therapeutic intervention. Finally, the book reviews the ethical dimension of anti-aging intervention strategies. This book is immensely useful to scientists and researchers from various disciplines in the life sciences. .
    Type of Medium: Online Resource
    Pages: XIV, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811974434
    DDC: 612.028
    Language: English
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  • 13
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biology Technique. ; Experimental immunology. ; Pharmaceutical chemistry. ; Medicine Research. ; Biology Research. ; Cytology. ; Clinical biochemistry. ; Immunological Techniques. ; Pharmaceutics. ; Biomedical Research. ; Cell Biology. ; Medical Biochemistry.
    Description / Table of Contents: Antibody-Drug Conjugates Basic Concepts and Structures -- Relationship between target and specific action of antibody-drugs conjugates -- The internalization and therapeutic activity of antibody drug conjugate -- The internalization and intracellular trafficking of ADC -- Distribution and metabolism of antibody-drug conjugates -- Application of Antibody fragments in ADCs -- Novel Targeting Carriers in Antibody-drug Conjugates -- Site-specified Conjugating Technology and Application -- Determination of drug-to-antibody ratio of ADCs -- Pharmacokinetic study of antibody-drug conjugates.
    Abstract: This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs. This book combines the basic theory with the research technology. It can be used as a reference book for students, teachers and researchers of biomedical field.
    Type of Medium: Online Resource
    Pages: IX, 135 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811956386
    DDC: 571.96028
    Language: English
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  • 14
    Keywords: Neurosciences. ; Public health. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Public Health. ; Biomedical Research.
    Description / Table of Contents: 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection.
    Abstract: This book examines the correlation of the coronavirus disease-19 [CE1] [AAS2] (COVID-19) infection with sleep, circadian rhythm, and sleep disorders. The chapters of the book explore sleep problems during the COVID-19 pandemic and its association with psychological distress and also review the prevalence of clinical cases of insomnia, anxiety, and depression in COVID-19 patients. The book further presents the correlation between sleep, circadian rhythms, and immunity that contributes toward more severe COVID-19. It summarizes the evidence on the interplay between circadian biology, sleep, and COVID-19. The chapters of the book discuss the relationship between obstructive sleep apnea (OSA) and adverse COVID-19 outcomes. Towards the end, the book presents studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin and provides mechanistic insights into the potential therapeutic use of melatonin during the SARS-CoV-2 infection. The last chapter describes the publication output of sleep-related research during the pandemic and provides an overview and trends on sleep and covid-19 publication output. This book is an excellent source for neurologists, sleep specialists, and public health specialists.
    Type of Medium: Online Resource
    Pages: XXVI, 430 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819902408
    Series Statement: Progress in Sleep Research,
    DDC: 612.8
    Language: English
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  • 15
    Keywords: Botany. ; Plant physiology. ; Agricultural genome mapping. ; Agriculture. ; Plant Science. ; Plant Physiology. ; Agricultural Genetics. ; Agriculture.
    Description / Table of Contents: 1. Importance of integrating physiological breeding to augment crop breeding -- 2. Stacking of complex traits through physiological pre breeding -- 3. Strategies to develop heat and drought tolerant wheat varieties following physiological breeding -- 4. Developing crop varieties by physiological breeding for improving plant nutrition -- 5. Role of Transpiration in Regulating Leaf Temperature and its Application in Physiological Breeding -- 6. Photosynthesis as a trait for improving yield potential in crops -- 7. Cuticular waxes and its application in crop improvement -- 8. Radiation use efficiency (RUE)-target for improving yield potential: Current status and future prospect -- 9. Application of Stable Isotopes in Crop Improvement -- 10. Root phenotyping for improved resource use efficiency in crops -- 11. Root system architecture and phenotyping for improved resource use efficiency in crops -- 12. Harnessing Root associated traits and Rhizosphere efficiency for Crop improvement -- 13. High throughput phenomics of crops for water and nitrogen stress -- 14. Metabolomics as a selection tool for abiotic stress tolerance in crops -- 15. Remote Sensing Algorithms and their Applications in Plant Phenotyping -- 16. Endophyte mediated crop improvement: Manipulation of abiotic stress‐specific traits -- 17. Impact of high temperature stress on selected food grain crops -- 18. Morpho-physiological basis of finger millet to withstand climatic extremes: A special reference to drought -- 19. Comprehending the physiological efficiency of millets under abiotic stress -- 20. Role of Next-generation sequencing in trait identification, genetic mapping, and crop improvement -- 21. Application of Artificial Intelligence and Machine Learning in Agriculture.
    Abstract: This book covers different physiological processes, tools, and their application in crop breeding. Each chapter emphasizes on a specific trait/physiological process and its importance in crop, their phenotyping information and how best it can be employed for crop improvement by projecting on success stories in different crops. It covers wide range of physiological topics including advances in field phenotyping, role of endophytic fungi, metabolomics, application of stable isotopes, high throughput phenomics, transpiration efficiency, root phenotyping and root exudates for improved resource use efficiency, cuticular wax and its application, advances in photosynthetic studies, leaf spectral reflectance and physiological breeding in hardy crops like millets. This book also covers the futuristic research areas like artificial intelligence and machine learning. This contributed volume compiles all application parts of physiological tools along with their advanced research in these areas, which is very much need of the hour for both academics and researchers for ready reference. This book will be of interest to teachers, researchers, climate change scientists, capacity builders, and policy makers. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, physiology, botany, ecology, and environmental sciences. National and international agricultural scientists will also find this a useful resource.
    Type of Medium: Online Resource
    Pages: XIV, 457 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811974984
    DDC: 580
    Language: English
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  • 16
    Keywords: Plant physiology. ; Stress (Physiology). ; Plants. ; Plant molecular biology. ; Agronomy. ; Plant Physiology. ; Plant Stress Responses. ; Plant Molecular Biology. ; Agronomy.
    Abstract: This edited volume provides state-of–the-art overview of abiotic stress responses and tolerance mechanisms of different legume crops viz., chickpea, mung bean, lentil, black gram, cowpea, cluster bean, soybean and groundnut. Legumes play an important role in human nutrition and soil health through fixation of nitrogen. Legume production and productivity are vulnerable to different abiotic stresses. A proper understanding about the physiological and molecular basis of the legume crops is essential for genetic improvement of abiotic stress tolerance. This book consists of 15 chapters covering physiological and biochemical basis, molecular physiology, molecular breeding, genetics, genomics, transgenics, epigenetics of drought, saline, high temperature and nutrient deficiency stresses, and the role of microRNAs in abiotic stress tolerance. This volume offers new perspectives in legume crop abiotic stress management, and is useful for various stakeholders, including post graduates students, scientists, environmentalists and policymakers.
    Type of Medium: Online Resource
    Pages: XV, 390 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811958175
    DDC: 571.2
    Language: English
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  • 17
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Pharmacology. ; Plant biotechnology. ; Molecular biology. ; Ecology . ; Plant Physiology. ; Pharmacology. ; Plant Biotechnology. ; Molecular Biology. ; Ecology.
    Description / Table of Contents: Chapter 1. Medicinal plants and abiotic stress: An overview -- Chapter 2. Medicinal plants proteomics in response to abiotic stresses -- Chapter 3. Medicinal plants metabolomics in response to abiotic stresses -- Chapter 4. Secondary metabolite production in medicinal plants under abiotic stress -- Chapter 5. Effect of temperature (cold and hot) stress on medicinal plants -- Chapter 6. Effect of water stress (drought and waterlogging) on medicinal plants -- Chapter 7. Effects of gaseous pollutants on medicinal plants -- Chapter 8. Impact of salinity stress on medicinal plants -- Chapter 9. Impact of aridity on specialized metabolism: Concentration of natural products in plants -- Chapter 10.The role of PGPRs in medicinal plants under abiotic stress -- Chapter 11. Effect of mineral nutrition and PGRs on biosynthesis and distribution of secondary plant metabolites under abiotic stress -- Chapter 12. Impact of phytoprotectants on growth and yield of medicinal plants under abiotic stress -- Chapter 13. Biostimulants and phytohormones improve productivity and quality of medicinal plants under abiotic stress -- Chapter 14. Light (high light/UV radiation) modulates adaptation mechanisms and secondary metabolite production in medicinal plants -- Chapter 15. Recent Strategies to engineer alkaloid biosynthesis in medicinal plants -- Chapter 16. Genome-editing strategies for enhanced stress tolerance in medicinal plants -- Chapter 16. Phytoremediation potential of medicinal plants -- Chapter 17. Phytoremediation potential of medicinal plants.
    Abstract: This book provides a comprehensive overview of medicinal plants and their interaction with abiotic stress in terms of morphological, physiological, biochemical, and molecular variations, and explains the adaptation and tolerance mechanisms involved. It presents various mechanisms that become operative in medicinal plants to combat stressful situations. The book discusses the secondary metabolites and/or bioactive compounds produced in medicinal plants under abiotic stress conditions, and the use of biostimulants and/or phytoprotectants to alleviate the adverse effects of abiotic stresses on medicinal plants. Additionally, it is likely to address opportunities and challenges in molecular and omics studies of medicinal plants under abiotic stress conditions. Overall, the chapters are developed by eminent subject experts with due care and clarity and cover an up-to-date literature review with relevant illustrations. The book would cater to the need of graduate and post-graduate students, researchers as well as scientists, and may attract the attention of pharmaceutical companies/industrialists and health policymakers.
    Type of Medium: Online Resource
    Pages: XI, 469 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811956119
    DDC: 571.2
    Language: English
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  • 18
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Research Methodology. ; Clinical medicine Research. ; Biomedical Research. ; Research Skills. ; Clinical Research.
    Description / Table of Contents: Section I: Understanding Grant Writing: What is your Aim (Ambition-Interest-Mission), and what you want to do -- What is a grant? How to prepare for writing a grant proposal application -- Funders Perspective: What the funding body expects from researchers? -- Funding organizations for science and healthcare -- Obtaining letters of support -- Section II: The process for grant writing: Writing a Grant Proposal for a Single Centre Study: step-by-step approach -- Budgeting the project-detailing the required funding and expenditure -- Proving the competency of the researcher and the adequacy of the infrastructure to carry out the research -- Agreement and MOU – ethical and legal aspects of funding for healthcare research -- Write an impressive cover page (Covering letter) and abstract for the grant proposal application -- Surveillance plan and site visit – Roles and rights of the researcher and the funding agency -- Sources of funding and acknowledgment – Good Clinical Practice Guidelines -- Writing a grant proposal for a Collaborative study -- Checklist for grant proposal – Mandatory elements -- Tips for improvising the chance of getting the grant -- Dealing with The Rejected Grant Proposal- Learning From The Mistakes -- Section III: Grant writing for specific regional funding organizations: Preparing a grant proposal for medical research in the UK -- Preparing a grant proposal for the USA -- Preparing a Grant Proposal for Australia -- Proposal Writing for Grant Application in Malaysia -- Grant writing for other Asian countries.
    Abstract: Conducting research requires resources to meet the research need. The resources in the research institutes/ centers are often inadequate, limiting the research outcome. Research grants help overcome those limitations and help the researchers carry out quality research without any restriction. Grant proposal writing is an essential skill to be mastered by every researcher. However, the majority of the medical schools, except the few research institutes, do not have a structured learning module for obtaining grants. On most occasions, the skill of writing grant proposals goes by self-learning. For students, it is burdening due to the tremendous time consumed to learn the craft of writing the grant proposal and the exhausting clinical and academic work. This book is carefully prepared to keep in mind the difficulties faced by the young researchers and the students concerning choosing a funding agency, grant makers' expectations, budgeting, surveillance and site visits, rights of the researcher and the funding agency, and ethical and legal aspects of obtaining the grant. The book also covers the alternate plan for partial funding or interruption of the financing, reporting the source of funding and acknowledgment, good clinical practice guidelines, and dealing with the rejected grant proposal. The research projects are often dropped or modified extensively due to the limited resources in the existing facility. The researchers are forced to compromise the research objective due to expensive requirements. There is a shortage of awareness regarding the availability of funding and grant for the conduct of research. Even if the researchers are aware of obtaining the financing, there is a lack of training in grant proposal writing, which is essential in getting the research funding. This book on grant proposal writing for medical and healthcare professionals covers such difficulties and deficiencies. It will provide complete companionship from knowing the funding agency to obtaining the grant. .
    Type of Medium: Online Resource
    Pages: XX, 247 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811970184
    DDC: 610.72
    Language: English
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  • 19
    Keywords: Medicine Research. ; Biology Research. ; Drug delivery systems. ; Genetics Research. ; Imaging systems in biology. ; Biology Technique. ; Biomedical Research. ; Drug Delivery. ; Genetics Research. ; Biological Imaging. ; Biological Techniques.
    Description / Table of Contents: Chapter 1. Editorial: Biosystems -- 2. Potential of Biotechnology in cancer management -- 3. Biosimilars: Promising and Rapidly Emerging Biotherapeutics -- 4. Applications of Nanomaterials in Medicine: Current status and future scope -- 5. Biomedical Applications of Nanofluids in Drug Delivery.
    Abstract: The book gives an insight into the theoretical background, conceptual understanding, latest developments, and applications in the field of pharmaceuticals in general and drug design, discovery, biosystems, and biomedical and drug delivery technologies in particular . Knowledge is drawn from various disciplines such as Chemistry, Biology, Material Science and Engineering, Statistics, Biomedicine, and Genetics . A host of applications like bio-imaging, novel biological agents, testing, characterization and validation of drugs, computer-based models in drug design, and application of statistical tools in data analysis, design, and development of drug delivery systems, and ecosystems are dealt with in detail. The said book undoubtedly confirms the requirements of the postgraduate students, research scholars, academicians, scientists, and researchers from the academia, pharmaceutical, biotechnology, and chemical engineering domain. The book covers a conceptual understanding of the exploration of drugs in tandem with intended uses, sound ecosystem development, and carriers for drug and supplement delivery.
    Type of Medium: Online Resource
    Pages: XX, 289 p. 58 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819952816
    DDC: 610.72
    Language: English
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  • 20
    Keywords: Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Drug delivery systems. ; Medical Ethics. ; Clinical Research. ; Biomedical Research. ; Drug Delivery. ; Medical Ethics.
    Description / Table of Contents: Chapter 1. The Roadmap to Research: Fundamentals of a Multifaceted Research Process -- Chapter 2. Processes involved in the generation of novel ideas -- Chapter 3. Creativity and critical thinking contribute to scholarly achievement -- Chapter 4. Writing protocols in Pharmacological studies -- Chapter 5. Basics of Designing General Toxicology Studies -- Chapter 6. General design considerations in Reproductive and developmental toxicity studies -- Chapter 7. Genetic toxicology studies -- Chapter 8. Rodent Carcinogenicity Studies.-Chapter 9. Designing studies in pharmaceutical and medicinal chemistry -- Chapter 10. Experimental protocols in phytochemistry and natural products: an ever-evolving challenge -- Chapter 11. Drug substance/ product quality analysis (Quality assessment) -- Chapter 12. Drug Delivery Systems: Lipid Nanoparticles Technology in Clinic -- Chapter 13. Pharmacokinetic studies for drug development -- Chapter 14. New Alternative Methods in drug safety assessment -- Chapter 15. Animal models for the study of human disease -- Chapter 16. Physiologically based Pharmacokinetic Modelling in Drug Discovery and Clinical Development: A Treatise on Concepts, Model Workflow, Credibility, Application and Regulatory Landscape -- Chapter 17. Design and conduct of pharmacokinetics studies influenced by extrinsic factors -- Chapter 18. Specific Populations: Clinical Pharmacology Considerations -- Chapter 19. Impact of genetic variation on drug response.-Chapter 20. Phases of clinical trials -- Chapter 21. Common clinical trial designs -- Chapter 22. Elements of clinical trial protocol design -- Chapter 23. Good clinical practice in clinical trials, substantial evidence of efficacy, and interpretation of the evidence -- chapter 24. Grandfathered Drugs of 1938 in the United States -- Chapter 25. General overview of the statistical issues in clinical study designs -- Chapter 26. Introduction to pharmacoepidemiology and its application in clinical research -- Chapter 27. Pharmacovigilance through phased clinical trials, post-marketing surveillance and ongoing life cycle safety -- Chapter 28. The design and statistical analysis of randomized pre-clinical experiments -- Chapter 29. Descriptive and Inferential Statistics in Biomedical Sciences: an overview -- Chapter 30. Principles and applications of statistics in biomedical research: parametric and non-parametric tests including tests employed for Post-hoc analysis -- Chapter 31. Artificial intelligence generative chemistry design of target-specific scaffold-focused small molecule drug libraries -- Chapter 32. Artificial intelligence technologies for clinical data pharmacoanalytics. Case studies on Alzheimer’s disease -- Chapter 33. Bioinformatics: Theory and Application -- Chapter 34. Drug targets and drug discovery research -- Chapter 35. Role of Nonclinical Programs in Drug Development -- Chapter 36. Drug repurposing: strategies and study design in bringing back old drugs to the mainline -- Chapter 37. Empowering knowledge on efficient literature search: an overview of biomedical search engines and databases -- Chapter 38. Literature Reviews: An Overview of Systematic, Integrated, and Scoping Review -- Chapter 39. How To Create A Bibliography -- Chapter 40. Publication metrics /Bibliometrics -- Chapter 41. How to write a scientific paper -- Chapter 42. Preparing and structuring a manuscript for publication -- Chapter 43. Writing a scientific article -- Chapter 44. How to Present Results in a Research Paper -- Chapter 45. Communicating results of quantitative research -- Chapter 46. How to Efficiently Write a Persuasive Discussion Section -- Chapter 47. Submitting a manuscript for publication, the peer review process, and getting past the gatekeepers -- Chapter 48. Writing a Postgraduate or Doctoral Thesis: A Step-by-Step Approach -- Chapter 49. Poster presentation at scientific meetings -- Chapter 50. Strategies for the preparation and delivery of oral presentation -- Chapter.-51. Grant Process and Peer Review ─ US National Institutes of Health System -- Chapter 52. Rigor and specifics in writing research proposal -- Chapter 53. Writing research grant proposals ─ from an Indian Perspective -- Chapter 54. Funding opportunities (resources) in biomedical sciences: Indian perspective -- Chapter 55. Mentorship in biomedical sciences -- chapter 56. Commercializing the technology – transitioning from the academic lab to the market -- Chapter 57. Patent law fundamentals for biomedical scientists -- Chapter 58. Research integrity: responsible conduct of research -- Chapter 59. Publication integrity, authorship, and misconduct.
    Abstract: The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated into the text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.
    Type of Medium: Online Resource
    Pages: XXII, 941 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819912841
    DDC: 615.50724
    Language: English
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  • 21
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Plant molecular biology. ; Plants Development. ; Plant Physiology. ; Plant Molecular Biology. ; Plant Development.
    Description / Table of Contents: UNIT I. TRANSPORT OF WATER AND NUTRIENTS -- 1. Concepts of Plant Water Relations -- 2. Essential and Functional Mineral Elements -- 3. Mechanisms of Water and Solute Transport -- UNIT II. METABOLISM -- 4. Concepts in Metabolism -- 5. Photosynthesis -- 6. Source-to-Sink Translocation of Photoassimilates -- 7. Respiration -- 8. ATP Synthesis -- 9. Metabolism of Storage Carbohydrates -- 10. Lipid Metabolism -- 11. Nitrogen Metabolism -- 12. Sulfur, Phosphorus and Iron Metabolism -- UNIT III. DEVELOPMENT -- 13. Light Perception and Transduction -- 14. Plant Growth regulators – An Overview -- 15. Auxins -- 16. Cytokinins -- 17. Gibberellins -- 18. Abscisic Acid -- 19. Ethylene -- 20. Brassinosteroids -- 21. Jasmonic Acid -- 22. Novel Plant Growth Regulators and Gaseous Signaling Molecules -- 23. Signal Perception and Transduction Mechanisms -- 24. Embryogenesis, Growth and Differentiation -- 25. Flowering -- 26. Pollination, Fertilization and Seed Development -- 27. Fruit Development and Ripening -- 28. Seed Dormancy and Germination -- 29. Plant Movements -- 30. Senescence and Programmed Cell Death -- UNIT IV. STRESS PHYSIOLOGY -- 31. Abiotic Stress -- 32. Biotic Interactions -- UNIT V. APPLIED PLANT PHYSIOLOGY -- 33. Secondary Metabolites -- 34. Crop Physiology and Biotechnology -- GLOSSARY -- SUBJECT INDEX.
    Abstract: This textbook is second edition of popular textbook of plant physiology and metabolism. The first edition of this book gained noteworthy acceptance (more than 4.9 Million downloads) among graduate and masters level students and faculty world over, with many Universities recommending it as a preferred reading in their syllabi. The second edition provides up to date and latest information on all the topics covered while also including the basic concepts. The text is supported with clear, easy to understand Figures, Tables, Box items, summaries, perspectives, thought-provoking multiple-choice questions, latest references for further reading, glossary and a detailed subject index. Authors have also added a number of key concepts, discoveries in the form of boxed- items in each chapter. Plant physiology deals with understanding the various processes, functioning, growth, development and survival of plants in normal and stressful conditions. The study involves analysis of the above-stated processes at molecular, sub-cellular, cellular, tissue and plant level in relation with its surrounding environment. Plant physiology is an experimental science, and its concepts are very rapidly changing through applications from chemical biology, cytochemical, fluorometric, biochemical and molecular techniques, and metabolomic and proteomic analysis. Consequently, this branch of modern plant biology has experienced significant generation of new information in most areas. The newer concepts so derived are being also rapidly put into applications in crop physiology. Novel molecules, such nanourea, nitric oxide, gaseous signalling molecules like hydrogen sulphide, are rapidly finding significant applications among crop plants. This textbook, therefore, brings forth an inclusive coverage of the field contained in 35 chapters, divided into five major units. It serves as essential reading material for post-graduate and undergraduate students of botany, plant sciences, plant physiology, agriculture, forestry, ecology, soil science, and environmental sciences. This textbook is also of interest to teachers, researchers, scientists, and policymakers. .
    Type of Medium: Online Resource
    Pages: XXVII, 899 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789819957361
    DDC: 571.2
    Language: English
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  • 22
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Environmental chemistry. ; Botanical chemistry. ; Plant physiology. ; Plant ecology. ; Environmental Chemistry. ; Plant Biochemistry. ; Plant Physiology. ; Plant Ecology.
    Description / Table of Contents: Past, Present and Future of Inorganic Carbon Assimilation -- Physiological Effects of Bicarbonate on Plants -- The Diversity, Plasticity and Roles of Carbonic Anhydrase in Inorganic Carbon Utilization in Plants -- Bidirectional Isotope Tracing Culture Technology and Bicarbonate Use by Plants -- Root-derived Inorganic Carbon Assimilation by Plants in Karst Environments.
    Abstract: This book summarizes the physiological effects of bicarbonate in plants and systematically introduces readers to a bidirectional isotope labeling tracer technique used to quantify the contribution of root-derived bicarbonate to total photosynthetic inorganic carbon assimilation in plants. This method helps to shed light on the role of dissolved inorganic carbon from the soil in overall photosynthesis, an aspect that has been underestimated or neglected entirely in the past. The book quantifies the capacity for root-derived bicarbonate assimilation in certain plant species and illustrates the coupling relationship between karstification and photosynthesis. Further, it demonstrates that root-derived bicarbonate utilization is as important as stomatal-derived inorganic carbon assimilation in biological evolution and plant adaptation to the environment. Using numerous models, it also illustrates carbon isotopic mixtures in complex inorganic carbon utilization and supplements the results with numerical calculations presented as tables and figures. In short, the book offers a strikingly new perspective on photosynthesis.
    Type of Medium: Online Resource
    Pages: XI, 213 p. 27 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819941254
    DDC: 577.14
    Language: English
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  • 23
    Keywords: Plant physiology. ; Stress (Physiology). ; Plants. ; Ecology . ; Plant Physiology. ; Plant Stress Responses. ; Ecology.
    Description / Table of Contents: Chapter 1 - Cadmium toxicity in plants: uptake, translocation and phyto-remediation strategy -- Chapter 2 - Heavy metal/metalloid contamination: Their sources in environment and accumulation in food chain -- Chapter 3 - Heavy metal/metalloid contamination: Impact on human health and mitigation strategies -- Chapter 4 - Heavy Metal Pollution in the Environment: Impact on Air Quality and Human Health Implications -- Chapter 5 - Heavy Metals Contamination in Surface Water Bodies through Construction & Demolition Waste: a case study of city of lakes - Bhopal, Madhya Pradesh, India -- Chapter 6 - Soil Deterioration and Risk Assessment of Heavy Metal Contamination -- Chapter 7 - Heavy metal contamination in ground water: Environmental concerns and mitigation measures -- Chapter 8 - Effect of Heavy Metals on Roadside Vegetation -- Chapter 9 - Heavy Metal Pollution in Atmosphere from Vehicular Emission -- Chapter 10 - Life Cycle Assessment of Heavy Metal Toxicity in the Environment -- Chapter 11 - Metalliferous soil remediation through heavy metal resistant plant growth-promoting bacteria: prospects and paradigms -- Chapter 12 - Phytoremediation of Heavy Metals - Reaction mechanisms and selected efficient technologies of heavy metals contamination -- Chapter 13 - Industrial Wastewater Treatment Strategies -- Chapter 14 - Brassica Juncea L.: A Potential Crop for Phytoremediation of Various Heavy Metals -- Chapter 15 - Phytoremediation of Heavy Metals -- Chapter 16 - Bioremediation of mining sites - sustainable approach to restore healthy ecosystem -- Chapter 17 - Industrial Pollution Management Approach -- Chapter 18 - Harnessing Green Energy Along with Precious Metal Recovery from Wastewater in Bio-electrochemical Systems: A Win-Win Scenario -- Chapter 19 - Minimization of Cadmium Toxicity in Wheat by Exogenous Application of Hydroxamate Siderophore. Chapter 20-Microbial remediation of Heavy Metals.
    Abstract: This contributed volume covers a comprehensive account of the sources, toxic biological as well as environmental impacts, and possible remediation strategies for contamination by heavy metals. In biological systems, toxic metals affect the integrity of cellular organelles and act as carcinogens causing chromosomal aberrations or as systemic toxicants leading to cardiovascular, neurobehavioral, and immunological disorders. In plants, they interfere with photosynthesis, fertility, metabolite, and chlorophyll synthesis. Toxicity induced by heavy metals involves mechanistic approaches that need to be understood properly. They cannot be degraded by biological or chemical means and thus can only be converted to less harmful forms. The conventional detection methods include biosensors, voltammetry, atomic absorption spectrometry, and inductively coupled plasma with atomic emission spectrometry. All such strategies for metal detection and mitigation strategies are covered in this title under one section. This book incorporates classical views along with modern scientific approaches to develop an understanding of the subject matter suitable for academicians, researchers, planners, policymakers, NGOs, and environmental consultancies and raise awareness on this concern. Topics representing diverse sections namely environmental impacts, biological effects, and methods used for detection and remediation have been included to address all possible contemporary issues on the topic in one concise volume. .
    Type of Medium: Online Resource
    Pages: XIII, 440 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903979
    DDC: 571.2
    Language: English
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  • 24
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Ecology . ; Medicine Research. ; Biology Research. ; Biotechnology. ; Environmental engineering. ; Bioremediation. ; Environmental management. ; Ecology. ; Biomedical Research. ; Biotechnology. ; Environmental Engineering/Biotechnology. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Microplastics in the freshwater and earthbound conditions: Prevalence, destinies, impacts and supportable arrangements -- Chapter 2. Effect of microplastics on microbial network -- Chapter 3.Quick estimation of microplastic in meat -- Chapter 4.Source, migration and toxicology of microplastics in soil -- Chapter 5.Impact of microplastics on nutrient -- Chapter 6.Agricultural plastic mulching as a source of microplastics in the terrestrial condition -- Chapter 7.Worldly and spatial varieties of microplastics in side of the road dust from provincial and urban area, : Implications for diffuse contamination -- Chapter 8.Microplastic particles in the Persian/Arabian Gulf -- Chapter 9.Impacts of microplastic biofilms on supplement cycling in recreated freshwater frameworks -- Chapter 10.Conveyance, bounty and dangers of microplastics in nature -- Chapter 11.Accumulation system of antibiotic medication hydrochloride from fluid arrangements by nylon microplastics -- Chapter 12.Expulsion of microplastics by means of drinking water treatment: Current information and future headings -- Chapter 13.Impacts of polystyrene microplastics on larval advancement, settlement, and transformation -- Chapter 14.Bioaccumulation of microplastics and its in vivo connections -- Chapter 15.Microplastics in oceanic situations: Toxicity to trigger biological results -- Chapter 16.Waterfront sea elements decrease the fare of microplastics to the vast sea -- Chapter 17.Barnacles as potential bioindicator of microplastic contamination in Hong Kong -- Chapter 18.Microplastic accumulation in remote ocean dregs from the Rockall Trough -- Chapter 19.Environmental microplastics: A survey on current status and points of view -- Chapter 20.The joined poisonous quality impact of microplastics and nonylphenol on microalgae Chlorella pyrenoidosa -- Chapter 21.Daylight interceded cadmium discharge from shaded microplastics containing cadmium color in watery stage -- Chapter 22.Environmental microplastic testimony in a urban environment and an assessment of transport -- Chapter 23.Biofilm modifies antibiotic medication and copper adsorption practices onto polyethylene microplastics.
    Abstract: This book provides an overview of the sources, occurrence, fate and solution of microplastics. Microplastics in sediment and soil environment have been only scarcely surveyed, and no profound discussion on microplastics removal is summarized until this book. Here we focus on sharing clear schematic information and the book sufficiently supports important microplastic topics: such as microbial network, microplastic toxicology and accumulation, agricultural plastics, nylon microplastics, polystyrene microplastics, polyethylene microplastics and many more. The book mainly provides an overview of recent advances in knowledge of sources, occurrence, distribution, chemical behavior and ecological threats while it also presents information related to feasible solutions for microplastic pollution management. This comprehensive resource will be valuable up-to-date knowledge for environmental scientists, ecotoxicologists, ecologists, marine biologists, environmental chemists in the academic field and this book is intended to be beneficial information for environmental managers, water suppliers, wastewater treatment, plastics manufacturer, and policy makers as well.
    Type of Medium: Online Resource
    Pages: XI, 129 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819906956
    DDC: 577
    Language: English
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  • 25
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Neurosciences. ; Biology. ; Molecular biology. ; Psychiatry. ; Biomedical Research. ; Neuroscience. ; Biological Sciences. ; Molecular Biology. ; Psychiatry.
    Description / Table of Contents: 1. Understanding schizophrenia: introductory aspect of the mental disorder from various perspectives -- 2. Genetic mutations and Alternative splicing in schizophrenia -- 3. Understanding the Chemical Interactions in the Brain of Schizophrenia Patients -- 4. A diagnostic perspective of schizophrenia: from past to present -- 5. Is it schizophrenia or not? - Different Biological characterization -- 6. A neurobiological aspect of schizophrenia and the relationship between neurological disorders: depression, anxiety, epilepsy -- 7. Clinical treatment available for schizophrenia -- 8. Insights into the neuro-pharmacological treatment of schizophrenia: past, present, and future -- 9. Managing Schizophrenia – A Challenge for Physicians -- 10. Pharmacotherapy and Emerging Treatment Strategies for Schizophrenia -- 11. Alternative Therapies used in Schizophrenia -- 12. Different phases of schizophrenia patients: from the psychological perspective -- 13. Stigmatizing Attitudes Towards Patients with Schizophrenia Among Medical Professionals and General Population -- 14. Rehabilitation of Schizophrenia-Practical Interventions -- 15. Consumption of Cannabis: A risk factor or a therapeutic agent for patients with Schizophrenia -- 16. Medical Imaging and Schizophrenia: A Study on State-of-art Applications -- 17. Schizophrenia and its Effect on Marital Satisfaction -- 18. The mortality rate in schizophrenia.
    Abstract: This book provides the reader with a thorough understanding of schizophrenia as a complex brain disorder by explaining the various aspects investigated for its cognizance from epigenetics to chemistry and physics to computational approaches. The book covers the key notions of schizophrenia from a variety of facets such as neurogenetics, neurochemistry, neuropharmacology, neurobiology, psychotherapy, psychiatric treatment, cognitive studies, behavioral and societal studies, and computational neurosciences. Individual chapters are focused on crucial topics such as cognitive-behavioral therapy, brain functioning, computational neuroscience, neuro-imaging, and many more. This book explains each section and chapter with utmost clarity to maintain comprehensiveness for every kind of reader. This book covers various classical as well as recent topics from basic to advance level knowledge regarding schizophrenia. The book's contributions regarding its inclusivity of topics, comprehensiveness of language, diversity in knowledge, and focus on the subject will attract all kinds of readers. It can be considered a single comprehensive handy reference book for beginners, including medical students, neuroscientists, researchers, clinicians, and medical practitioners. Cognizance of Schizophrenia will be an invaluable asset for all who are involved in neuroscience research or clinical studies.
    Type of Medium: Online Resource
    Pages: XII, 312 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811970221
    DDC: 610.72
    Language: English
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  • 26
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Plant genetics. ; Biodiversity. ; Plant Physiology. ; Plant Genetics. ; Biodiversity.
    Description / Table of Contents: Cowpea -- Chapter-1: Introduction -- Chapter-2: Genetic improvement and variability -- Chapter-3: Quality and nutrition -- Chapter-4: Cultivation -- Chapter-5: Plant Protection -- Chapter-6: Physiology and Abiotic stresses -- Chapter-7: Genetic markers and Biotechnology -- Horsegram -- Chapter-1: Introduction -- Chapter-2: Genetic improvement and variability -- Chapter-3: Quality and nutrition -- Chapter-4: Cultivation -- Chapter-5: Plant Protection -- Chapter-6: Physiology and Abiotic stresses -- Chapter-7: Genetic markers and Biotechnology -- Moth bean -- Chapter-1: Introduction -- Chapter-2: Genetic improvement and variability -- Chapter-3: Quality and nutrition -- Chapter-4: Cultivation -- Chapter-5: Plant Protection -- Chapter-6: Physiology and Abiotic stresses -- Chapter-7: Genetic markers and Biotechnology.
    Abstract: This authored book gives insight into the morphology, physiology, genetics, plant protection and biotechnology of three important arid legumes, viz., moth bean, cowpea and horse gram. There are seven chapters for each crop that provide in-depth information on cultivation, genetic improvement, plant protection measures, management of physiological and abiotic stresses along with related genetic markers and biotechnological advances pertaining to these legumes. The chapters present research findings and brief reviews concerning the advances made in the improvement of these legumes. Legumes are utilized as pulses or grains aiding as an important source of protein for both human and animal consumption and also provide raw materials to the food and feed industries. They are also valuable for soil building, improving soil quality and biological nitrogen fixation. Physiology and genetics provide an inimitable source of information on the distinct aspects of basic and applied legume research for general readers, students, academicians and researchers. Arid legumes are crops characterized by inherent features and capabilities to withstand adverse and harsh climatic conditions, significantly replenish the soil, as well as provide protein and micronutrients. Adaptability to several stresses including drought makes them key to agriculture in areas receiving scanty rainfall. This comprehensive book disseminates significant information on the genetic diversity, cultivation, manipulation through mutagenic techniques, molecular biology and other breeding techniques. The book, therefore, is of importance to teachers, researchers and policymakers who are interested to acquire knowledge about moth bean, cowpea and horse gram. It also serves as an additional reading material for MSc and PhD students of agriculture and environmental sciences. The book is also useful to national and international agricultural scientists and policymakers.
    Type of Medium: Online Resource
    Pages: XXI, 396 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811999567
    DDC: 571.2
    Language: English
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    Keywords: Plant physiology. ; Stress (Physiology). ; Plants. ; Microbial ecology. ; Plant Physiology. ; Plant Stress Responses. ; Microbial Ecology.
    Description / Table of Contents: Chapter 1. Genetic and genomic resources of range grasses- status and future prospects -- Chapter 2. Forage genetic resources and scope for allele mining of abiotic stress tolerance -- Chapter 3. Breeding for developing higher productive tree-based forage under stress environments -- Chapter 4. Impact of Climate change on forage crop production with special emphasis on diseases and mitigation strategies through breeding and molecular approaches -- Chapter 5. Effect of nano-priming on maize under normal and stressful environment -- Chapter 6. Oxidative stress and antioxidant defense in mitigating abiotic stresses in forage crops: A physiological and biochemical perspective -- Chapter 7. Forage cropping under climate smart farming: a promising tool to ameliorate salinity threat in soils -- Chapter 8. Forage cultivation under challenging environment -- Chapter 9. Potentials and Opportunities of Agro-forestry Under Climate Change Scenario -- Chapter 10. Climate Change Impact on Forage Characteristics: An Appraisal for Livestock Production -- Chapter 11. Sustainable Use of Paddy Straw as Livestock Feed: A Climate Resilient Approach to Crop Residue Burning -- Chapter 12. Engineering Interventions for Climate Resilient Forage Production -- Chapter 13. Promotion of improved forage crop production technologies: Constraints and strategies with special reference to climate change. .
    Abstract: This edited book is collection of information on molecular interventions needed for climate-resilient forage crops. The main focus is to address the gap in the advanced scientific knowledge for the forage species. Agriculture is extremely vulnerable to climate, and even slight change in climatic factors such as temperature causes tremendous losses in yield potential. Forage crops are crucial in global food security and environmental sustainability and face several environmental challenges in field conditions. However, the research on forage crops is far-off compared to agricultural crops and causes a substantial gap in forage demand and productivity. Further, this gap is directly associated with animal health, reproduction, and productivity. Abiotic stresses mainly affect the plant's crucial processes, ultimately reducing the final yield. The problem of abiotic stresses is more frequent in forage crops as they are growing and cultivated in less productive soil and harsh conditions. This book discusses current aspects of crucial physiological, biochemical and molecular processes in forage crops, which are essential for forage crops improvement. The text's major focus is on the advanced technologies and approaches such as seed priming, bio-fortification, breeding, omics, transgenic and bioengineering of metabolic pathways in unique ways, which helps us develop innovative solutions for forage crops. This book covers all the crucial advance technologies, which help mitigate the abiotic stresses in forage crops. We believe that this book will initiate and introduce the readers to state-of-the-art developments and unique in this field of study. This book is of interest to teachers, researchers, climate change scientists, capacity builders, and policymakers. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences. National and international agricultural scientists and policymakers will also find this a worthwhile read.
    Type of Medium: Online Resource
    Pages: XXIV, 236 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819918584
    DDC: 571.2
    Language: English
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    Keywords: Toxicology. ; Medicine Research. ; Biology Research. ; Microbiology. ; Toxicology. ; Biomedical Research. ; Microbiology.
    Description / Table of Contents: Chapter 1. Editorial: 3D Skin models for cosmetic safety/ toxicity studies: Bridging established methods and novel technologies -- Chapter 2. Artificial skin models for animal-free testing: 3D Skin reconstruct approach, a journey in past two decades -- Chapter 3. Fabrication of ready-to-use ex vivo human skin models for chemical testing: current status and challenges -- Chapter 4. Human skin reconstructs model systems in mechanistic research, safety and efficacy studies of cosmetics: Pros and cons -- Chapter 5. Skin-on-a-Chip Microfluidic Devices: Production, Verification and Uses in Cosmetic Toxicology -- Chapter 6. 3D Bioprinting of skin tissue model -- Chapter 7. Solar radiations and phototoxicity of cosmetics: Avenues of in vitro skin models -- Chapter 8. Cosmetic Ingredients: Various Efficacy-Based testing methods in the 3D Skin based Model Systems -- Chapter 9. Animal component-free medium for long term maintenance of human skin explants and its application in toxicity studies of cosmetics -- Chapter 10. Regulatory requirements for safety/efficacy assessment of cosmetics/nano cosmetics products: Challenges and opportunities -- Chapter 11. Integrated approaches to testing and assessment (IATA) for cosmetic and personal health care products -- Chapter 12. Approach for in-silico validation of safety/ toxicity data for cosmetics -- Chapter 13. Role of omics approaches in the toxicity/ safety studies of cosmetics -- Chapter 14. Application of 3D skin models in safety/ toxicity of fragrances, flavors, hair dyes, preservatives and colorants -- Chapter 15. Toxicokinetic and toxicodynamic studies of cosmetics and personal health care products using 3D skin models: Progress made and path ahead.
    Abstract: Efforts are being made by research organizations and cosmetic industries worldwide to develop more precise and targeted 3D models that mimic humans for testing cosmetic and personal health care product ingredients, following a complete ban on animal testing. This book includes several subtopics dedicated to the progress made, challenges faced, roadblocks encountered, and future prospects in the development and validation of 3D models for testing these products. The book consist of an editorial and 14 themed chapters that will showcase the significant progress made so far, challenges encountered, and future prospects in the development of 3D reconstruct models.
    Type of Medium: Online Resource
    Pages: XXII, 250 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819928040
    DDC: 615.90072
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Cancer. ; Tumors Immunological aspects. ; Biomedical Research. ; Cancer Biology. ; Cancer Microenvironment. ; Tumour Immunology.
    Description / Table of Contents: Chapter 1: Interactions in cancer ecosystem -- Chapter 2: Local niche construction -- Chapter 3: Pre-metastatic niche -- Chapter 4: Emerging concepts in cluster metastasis -- Chapter 5: Neuronal regulation in cancer ecosystem -- Chapter 6: Endocrinal regulation in cancer ecosystem -- Chapter 7: Innate immune system in cancer ecosystem -- Chapter 8: Adaptive immune system in cancer ecosystem -- Chapter 9: Inflammation in cancer ecosystem -- Chapter 10: Metabolic regulation in cancer ecosystem -- Chapter 11: Vascular regulation in cancer ecosystem -- Chapter 12: Microbial interaction in cancer ecosystem -- Chapter 13: Viral interaction in cancer ecosystem -- Chapter 14: Evolution of cancer ecosystem -- Chapter 15: Driving force of cancer ecosystem -- Chapter 16: Modeling, visualizing and subtyping the cancer ecosystem -- Chapter 17: Bio-engineering methods to mimic cancer ecosystem -- Chapter 18: Cancer ecosystem-directed therapeutic strategies.
    Abstract: This book intends to report new concept of onco-spheres in cancer ecosystem. Onco-spheres are defined as where cancer cells (living organisms) dynamically interact with nontumor cellular (other living organisms) and noncellular components (non-living environmental factors) in the ‘host’ internal environment (habitat) to construct a self-sustainable cancer ecosystem, which can be scoped at three different levels: primary/regional, distal and systemic onco-spheres. Cancer cells should be conceived as ‘living organisms’, interacting with cellular or noncellular components in the host internal environment, not only with the local tumor microenvironment (TME) but also constantly communicating with a distant organ niche as well interacting with the host’s nervous, endocrine and immune systems, to construct a self-sustainable ‘biosphere’, as we termed the tumor ecosystem. By looking at the interaction of cancer and host as a unique ecosystem, we will use ecology principles to further delineate the features of the dynamics of the tumor ecosystem. As the pioneer in proposing this concept, we feel that this full-scale overview of the tumor ecosystem is able to inform the readers about this concept, and to pave the way for designing novel therapeutic strategies on actionable targets within tumor ecosystem. The book is likely to be of interest to immunologist, biologist, medical students, researchers and general public who wish to learn more on this new concept of tumor ecosystem, and how this could be applied in many fields of research.
    Type of Medium: Online Resource
    Pages: XIX, 701 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819911837
    DDC: 610.72
    Language: English
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    Keywords: Biotechnology. ; Drug delivery systems. ; Biology. ; Pharmaceutical chemistry. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Drug Delivery. ; Biological Sciences. ; Pharmaceutics. ; Biomedical Research.
    Description / Table of Contents: Chapter 1.Computational and informatics methodologies in Drug Discovery, with focus on Natural Products -- Chapter 2.Structural biology an essential tool for Drug discovery and Development -- Chapter 3.Bioactivity guided fractionation and identification of bioactive molecules: A basic method in drug discovery -- Chapter 4.In–vitro methodologies for the safety assessment of drugs -- Chapter 5.In-vivo models for evaluation of Drug efficacy: Demand and Challenges -- Chapter 6.Preclinical In vivo Drug Development Studies: Limitations, Model Organisms and Techniques -- Chapter 7.Peptide Based Therapeutics and Drug Delivery Systems -- Chapter 8.Basics of Clinical Drug Development: Clinical Trial and Drug Development -- Chapter 9.Trailblazing contemporary frameworks for drug repurposing: A saga on drugs’ expedition to disinter the veiled destiny -- Chapter 10.Small molecules as promising tool for targeted cancer therapies: an overview of 21st century -- Chapter 11.Nanoparticles for Targeted Drug Delivery Systems with Cancer Therapy in Perspective -- Chapter 12.Biomimetic approach for the controlled drug delivery through 3D bioactive scaffolds: A novel strategy for tissue engineering applications -- Chapter 13.Perspectives on anti-tuberculosis drug discovery -- Chapter 14.Cofactor-Receptor interactions based pharmacophore design for development of novel inhibitors: A case study against Tuberculosis -- Chapter 15.Insilico identification of potential antivirals against SARS-CoV2 main protease and RBD of spike protein – A Drug Repurposing Approach -- Chapter16.Anti-malarial drug discovery and development: from bench to bedside.
    Abstract: This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines. .
    Type of Medium: Online Resource
    Pages: XV, 425 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811979521
    DDC: 660.6
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Stem cells. ; Developmental biology. ; Biomedical Research. ; Stem Cell Biology. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: Chapter 1. Hematopoietic Stem Cell Development in Mammalian Embryos -- Chapter 2. Hematopoietic Stem Cells and Their Bone Marrow Niches -- Chapter 3. Emerging Roles of Epigenetic Regulators in Maintaining Hematopoietic Stem Cell Homeostasis -- Chapter 4. Metabolism in Hematopoiesis and Its Malignancy -- Chapter 5. The Origin of Clonal Hematopoiesis and Its Implication in Human Diseases -- Chapter 6. Ex vivo Expansion and Homing of Human Cord Blood Hematopoietic Stem Cells -- Chapter 7. N6-methyladenosine RNA Modification in Normal and Malignant Hematopoiesis -- Chapter 8. Immune System Influence on Hematopoietic Stem Cells and Leukemia Development -- Chapter 9. Learning from Zebrafish Hematopoiesis -- Chapter 10. Multi-lineage Differentiation from Hematopoietic Stem Cells -- Chapter 11. Gene Editing in Hematopoietic Stem Cells -- Chapter 12. Aging, Causes and Rejuvenation of Hematopoietic Stem Cells.
    Abstract: This book renders a comprehensive understanding of hematopoietic stem cells (HSCs) from their embryonic development through adult maintenance to aging, in the studies conducted in zebrafish and mammals. Hematopoiesis provides a paradigm for understanding the development, maintenance, regeneration, aging and malignant transformation of mammalian organs. Sitting at the apex of the hematopoiesis hierarchy tree, HSCs orchestrate their proliferation, self-renewal, and differentiation to produce all the blood cell lineages throughout life, which represents the best example for somatic stem cell studies. In this book, key regulatory mechanisms for HSC self-renewal and differentiation are overviewed in an array of fields including epigenetics, metabolism and microenvironment regulation. It also highlights the HSC heterogeneity and clonal dynamics from the recent advanced single-cell technologies. This book elaborates on the research history of HSC studies and reveals how the insights from HSC studies shed light on their clinic application. It presents great value from the bench to the clinic.
    Type of Medium: Online Resource
    Pages: XV, 210 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819974719
    Series Statement: Advances in Experimental Medicine and Biology, 1442
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Stress (Physiology). ; Plants. ; Bioclimatology. ; Agriculture. ; Plant physiology. ; Plants Development. ; Hormones. ; Plant Stress Responses. ; Climate Change Ecology. ; Agriculture. ; Plant Physiology. ; Plant Development. ; Hormone.
    Description / Table of Contents: 1. Role of phytohormones in plant responses to acid rain -- 2. The complex interaction between elevated CO2 and hormones on the control of plant growth -- 3. Role of plant hormones in plant response to elevated CO2 concentrations – above- and below-ground interactions -- 4. The intriguous roles of phytohormones in plant response to ozone interacting with other major climate-change stressors -- 5. Role of phytohormones in plant responses to acid rain -- 6. The role of plant hormones in fruit response to photo-oxidative and heat stress -- 7. Phytochrome and hormone signaling crosstalk in response to abiotic stresses in plants -- 8. Phytohormone-mediated regulation of heat stress response in plants -- 9. Phytohormones and cold stress tolerance -- 10. Drought stress: involvement of plant hormones in perception, signaling and response -- 11. Involvement of phytohormones in flooding stress tolerance in plants -- 12. Roles of long-distance signals in nitrogen, phosphorus, and sulfur uptake and sensing in plants -- 13. Phytohormone involvement in plant responses to soil acidity -- 14. Plant response to toxic metals: emerging sources, phytohormone role and tolerance strategies.
    Abstract: This book provides new insights into the mechanisms of plant hormone-mediated growth regulation and stress tolerance covering the most recent biochemical, physiological, genetic, and molecular studies. It also highlights the potential implications of plant hormones in ensuring food security in the face of climate change. Each chapter covers particular abiotic stress (heat stress, cold, drought, flooding, soil acidity, ozone, heavy metals, elevated CO2, acid rain, and photooxidative stress) and the versatile role of plant hormones in stress perception, signal transduction, and subsequent stress tolerance in the context of climate change. Some chapters also discuss hormonal crosstalk or interaction in plant stress adaptation and highlight convergence points of crosstalk between plant hormones and environmental signals such as light, which are considered recent breakthrough studies in plant hormone research. As exogenous application or genetic manipulation of hormones can alter crop yield under favorable and/or unfavorable environmental conditions, the utilization of plant hormones in modern agriculture is of great significance in the context of global climate change. Thus, it is important to further explore how hormone manipulation can secure a good harvest under challenging environmental conditions. This volume is dedicated to Sustainable Development Goals (SDGs) 2 and 13. The volume is suitable for plant science-related courses, such as plant stress physiology, plant growth regulators, and physiology and biochemistry of phytohormones for undergraduate, graduate, and postgraduate students at colleges and universities. The book can be a useful reference for academicians and scientists involved in research related to plant hormones and stress tolerance.
    Type of Medium: Online Resource
    Pages: XVII, 372 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811949418
    DDC: 581.788
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biology. ; Bioinformatics. ; Medicine Research. ; Biology Research. ; Pharmacy. ; Drugs Design. ; Biotechnology. ; Biological Sciences. ; Bioinformatics. ; Biomedical Research. ; Pharmacy. ; Structure-Based Drug Design. ; Biotechnology.
    Description / Table of Contents: Chapter 1: Fundamentals of Computational Drug Design Approaches (CADD) -- Chapter 2: Molecular and Computational Modeling in Drug Design -- Chapter 3: Bioinformatics/Chemo-informatics Tools and Database in Drug Discovery -- Chapter 4: Computational Screening of Phytochemicals/Natural Products in Drug Discovery -- Chapter 5: Virtual Screening in Lead Discovery and Optimization -- Chapter 6: Target-based Screening (SBDD) in Lead Discovery -- Chapter 7: Pharmacophore-based and Similarity Search (LBDD) Screening in Lead Discovery -- Chapter 8: Receptor-based De Novo and Fragment-based Drug Design -- Chapter 9: Artificial Intelligence and Machine Learning in Drug Discovery -- Chapter 10: Network Pharmacology and System Biology Approaches -- Chapter 11: In Silico Pharmacology and Drug Repurposing Approaches -- Chapter 12: Advances in Bioinformatics and Computational Approaches in Drug Discovery -- Chapter 13: Challenges in Bioinformatics and Computational Approaches in Drug Discovery.
    Abstract: This book updates knowledge on recent advances in computational and bioinformatics tools/techniques and their practical applications in modern drug design and discovery programme. Also it encompasses fundamental principles, advanced methodologies and applications of various CADD approaches including several cutting-edge areas; presenting recent developments covering ongoing trends in the field of computer-aided drug discovery. Having contributions by a global team of experts, the book is expected to be an ideal resource for drug discovery scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, biologists, R&D personnel, researchers, students, teachers and those working in the field of drug discovery. It will fill the knowledge gaps that exist in the current CADD approaches and methodologies/ protocols being widely used in both academic and research practices. Further, a special focus on current status of various computational drug design approaches (SBDD, LBDD, De-novo drug design, Pharmacophore-based search), bioinformatics tools and databases, computational screening and modeling of phytochemicals/natural products, artificial intelligence and machine learning, and network pharmacology and system biology would certainly guide researchers, students or readers to conduct their research in the emerging area(s) of interest. It is also expected to be highly beneficial to different stakeholders working in the pharmaceutical and biotechnology industries (R&D), the academic as well as research sectors. .
    Type of Medium: Online Resource
    Pages: IX, 366 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819913169
    Series Statement: Interdisciplinary Biotechnological Advances,
    DDC: 570
    Language: English
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    Keywords: Stress (Physiology). ; Plants. ; Plant physiology. ; Botanical chemistry. ; Metabolism, Secondary. ; Plant Stress Responses. ; Plant Physiology. ; Plant Biochemistry. ; Plant Secondary Metabolism.
    Abstract: This book is a comprehensive collection of information on the role of plant phenolics in stress management in plants. The main focus of this book is to address the abiotic stress management in plants by plant phenolics under varied environments. Plant metabolic networks contribute significantly to the plasticity of plant metabolism, which is required to afford the sessile lifestyle of a land plant under changing environmental conditions. In natural systems, plants face a plethora of antagonists and thus possess a myriad of defenses and have evolved multiple defense mechanisms by which they can cope with various kinds of stresses for adaptation. Plant phenolics being ubiquitous have been extracted from every plant part such as roots, stem, leaves, flowers, fruits, and seeds and thus plays important role in adapting the plants to the varied environment. The book will provide readers with an up-to-date review of this dynamic field and sets the direction for future research. This book is of interest and use to a diverse range of topics of regulation of abiotic stress in plants. Bringing together work from leading international researchers, it is also a valuable reading material for plant and agricultural scientists, academics, researchers, students, and teachers wanting to gain insights into the role of plant phenolics in stress management in plants for sustainable agriculture.
    Type of Medium: Online Resource
    Pages: XVI, 461 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811964268
    DDC: 581.788
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Medical informatics. ; Quantitative research. ; Biomedical Research. ; Bioinformatics. ; Health Informatics. ; Data Analysis and Big Data.
    Description / Table of Contents: Chapter 1. Introduction to multi-omics -- Part 1. Omics integration techniques -- Chapter 2. Biomedical applications: the need for multi-omics -- Chapter 3. Omics technologies and big data -- Chapter 4. Multi-omics data mining techniques: algorithms and software -- Part 2. Applications of multi-omics analyses -- Chapter 5. Multi-omics data analysis for cancer research: colorectal cancer, liver cancer and lung cancer -- Chapter 6. Multi-omics data analysis for inflammation disease research: correlation analysis, causal analysis and network analysis -- Chapter 7. Microbiome data analysis and interpretation: correlation inferences and dynamic pattern discovery -- Chapter 8. Current progress of bioinformatics for human health.
    Abstract: This book features multi-omics big-data integration and data-mining techniques. In the omics age, paramount of multi-omics data from various sources is the new challenge we are facing, but it also provides clues for several biomedical or clinical applications. This book focuses on data integration and data mining methods for multi-omics research, which explains in detail and with supportive examples the “What”, “Why” and “How” of the topic. The contents are organized into eight chapters, out of which one is for the introduction, followed by four chapters dedicated for omics integration techniques focusing on several omics data resources and data-mining methods, and three chapters dedicated for applications of multi-omics analyses with application being demonstrated by several data mining methods. This book is an attempt to bridge the gap between the biomedical multi-omics big data and the data-mining techniques for the best practice of contemporary bioinformatics and the in-depth insights for the biomedical questions. It would be of interests for the researchers and practitioners who want to conduct the multi-omics studies in cancer, inflammation disease, and microbiome researches.
    Type of Medium: Online Resource
    Pages: XI, 167 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811982101
    Series Statement: Translational Bioinformatics, 19
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Plants Development. ; Stress (Physiology). ; Plants. ; Botanical chemistry. ; Plant Physiology. ; Plant Development. ; Plant Stress Responses. ; Plant Biochemistry.
    Description / Table of Contents: 1. Seed Quality: Variety Development to Planting – An Overview -- 2. Seed Development and Maturation -- 3. Seed Dormancy and Regulation of Germination -- 4. Seed Vigour and Invigoration -- 5. Seed Longevity and Deterioration -- 6. Principles of Quality Seed Production -- 7. Vegetable Seed Production -- 8. Principles of Variety Maintenance for Quality Seed Production -- 9. Hybrid Seed Production Technology -- 10. Seed Processing for Quality Upgradation -- 11. Seed Storage and Packaging -- 12. Role of Seed Certification in Seed Quality Assurance -- 13. Testing Seed for Quality -- 14. Seed Health: Testing and Management -- 15. Molecular Techniques for Testing Genetic Purity and Seed Health -- 16. Seed Quality Enhancement -- 17. Emerging Trends and Promising Technologies.
    Abstract: This open-access edited book is a collection of 17 chapters, synthesized primarily from the lectures delivered by eminent Indian and international experts during a series of capacity-building programmes organised in India during 2020 and 2021 under the aegis of 'Indo-German Cooperation on Seed Sector Development', a component of the Bilateral Cooperation between the Governments of India and Germany. Seed Science and Technology, a multi-disciplinary subject, is advancing rapidly keeping pace with the development of improved plant varieties and other climate-resilient technologies. Knowledge of the underlying biological processes and application of appropriate technologies for variety maintenance and seed production; quality assurance, testing and enhancement; processing, packaging and storage etc., are important in a seed programme. Chapters presented in the book is a blend of basic seed biology covering seed development, maturation, dormancy, germination, vigour and invigoration, and seed deterioration; variety maintenance and production of genetically pure seed of open-pollinated and hybrid varieties in a few key field crops and vegetables, and fundamentals of seed processing, packaging and storage; and seed quality assurance systems followed in different countries; testing the essential components of seed quality including seed health, application of molecular technologies for precision in testing, and enhancement of seed quality. It concludes by identifying the key areas of future seed research and technology development. The book covers the fundamentals and recent advances of seed science and technology with the latest research information and an exhaustive and updated list of references on different topics. It is expected to benefit the students as well as the scientists, faculty members and seed sector professionals, working in the public and private seed sectors, certification authorities and seed producing agencies in India, and elsewhere. .
    Type of Medium: Online Resource
    Pages: XVI, 430 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811958885
    DDC: 571.2
    Language: English
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    Keywords: Plant diseases. ; Stress (Physiology). ; Plants. ; Plant physiology. ; Plant molecular biology. ; Plant Pathology. ; Plant Stress Responses. ; Plant Physiology. ; Plant Molecular Biology.
    Description / Table of Contents: Chapter 1. Soil-borne Viruses: Outlook on Community and Recent Advances in Detection -- Chapter 2. An In Silico Outlook for the detection and surveillance of evolving and persistent plant pathogens -- Chapter 3. Emergent Tools and Techniques in Diagnosis of Soil-borne Phytopathogens -- Chapter 4. Diagnosis and Detection of Soil-borne Fungal Phytopathogens in Major Crops -- Chapter 5. Detection and diagnosis of important soil-borne pathogens -- Chapter 6. Genetic enhancement of biocontrol agent as effective management of soil borne disease -- Chapter 7. Red root rot disease of tropical estate forests: Pathogen identification, dispersal and management -- Chapter 8. Rhizospheric Microbiome: Soil and Plant Health Management -- Chapter 9. Detection and Management of Basal Stem Rot of Oil palm: Classical to Modern Approaches -- Chapter 10. Talaromyces flavus: an important rhizospheric inhabitant -- Chapter 11. Harnessing beneficial rhizospheric microorganisms for biotic stress management in medicinal and aromatic plants -- Chapter 12. Nematophagous fungi: Biology, Ecology and potential application -- Chapter 13. Rhizosphere Microbiome: Interactions with Plant and Influence in triggering Plant Disease Resistance -- Chapter 14. Rhizospheric functional attributes of Paenibacillus polymyxa in disease and nutrient management for sustainable crop production -- Chapter 15. Biochar mediated suppression of soil-borne pathogens in agronomically important crops: An Outlook -- Chapter 16. Harnessing rhizosphere microbiomes in crop productivity -- Chapter 17. Microbial Management of Fusarium wilt in Banana: A comprehensive overview -- Chapter 18. Soil Health Management and Microorganisms: Recent Developments.
    Abstract: This edited book provides an overview of omics technologies and methods for integration across multiple omics layers used in the plant disease diagnosis and developing management strategies. The book concentrates on the prevalence of soil-borne disease management in various important crops with use of different strategies, including host resistance and biological control etc. The special focus is on the resolving practical problems encountered after the resistance development in the pathogens against several chemical pesticides. Further, special attention is given to the emergence of new diseases or the re-emergence of old ones on several crops, and on the results and problems encountered by using microbial inoculants, biofumigation and other non-chemical control methods. This book has 18 contributory chapters from the eminent experts in the field of plant pathology, microbiology and biotechnology working on different aspects of soil-borne diseases of important agricultural crops. This edited volume is of interest and useful to researchers in plant pathology, agriculture sciences, plant genomics ecology, policy makers, also it is a valuable source of reference to the relevant researchers and students globally.
    Type of Medium: Online Resource
    Pages: XX, 493 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811983078
    DDC: 571.92
    Language: English
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  • 38
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biological transport. ; Cell membranes. ; Biomedical Research. ; Translational Research. ; Cell Biology. ; Membrane Trafficking.
    Description / Table of Contents: Section I. Extraction Methods -- Chapter 1. Updated Methods of Extracellular Vesicles Isolation -- Section II. Extracellular Vesicles in Cardiovascular Disease -- Chapter 2. Extracellular Vesicles and Pathological Cardiac Hypertrophy -- Chapter 3. Extracellular Vesicles and Cardiac Aging -- Chapter 4. Extracellular Vesicles and Ischemic Cardiovascular Diseases -- Chapter 5. Extracellular Vesicles and Hypertension -- Chapter 6. Extracellular Vesicles and Coronary Artery Disease -- Chapter 7. Extracellular Vesicles and Vascular Inflammation -- Chapter 8. Extracellular Vesicles and Muscle Atrophy Treatment -- Section III. Extracellular Vesicles in Metabolic Diseases -- Chapter 9. Extracellular Vesicles and Fatty Liver -- Chapter 10. Extracellular Vesicles and Obesity -- Chapter 11. Extracellular Vesicles in Bone Remodeling and Osteoporosis -- Section IV. Therapeutic Implications -- Chapter 12. Diagnosis of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 13. Therapeutics of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 14. Gene Therapy of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Section V. Future Prospects -- Chapter 15. Prospective Advances of Extracellular Vesicles Investigation in Cardiovascular and Metabolic Research -- Chapter 16. Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 17. Extracellular Vesicle Release from Platelets and their Contributions to Thrombosis.
    Abstract: This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819914432
    Series Statement: Advances in Experimental Medicine and Biology, 1418
    DDC: 610.72
    Language: English
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  • 39
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Molecular biology. ; Biophysics. ; Medicine Research. ; Biology Research. ; Cytology. ; Biochemistry. ; Non-coding RNA. ; Molecular Biology. ; Biophysics. ; Biomedical Research. ; Cell Biology. ; Biochemistry. ; Non-coding RNAs.
    Description / Table of Contents: Chapter 1. FUS aggregation by shear stress on pipetting and its suppression by non-coding RNA -- Chapter 2. Basics and recent advances in computational and theoretical methods for understanding the liquid-liquid phase separation -- Chapter 3.Promotion of liquid-liquid phase separation by G-quadruplex DNA and RNA -- Chapter 4. Phase regulation by chaperons -- Chapter 5. Regulation of aggregation of intrinsically disordered protein through phase separation: Risk management of phase separation -- Chapter 6. Molecular mechanisms of phase transition/separation of protein low-complexity sequences -- Chapter 7. Winding and Tangling. An Initial Phase of Membrane-less Organelle Formation (from a viewpoint of Cajal Bodies) -- Chapter 8. Formation and function of phase separated nuclear bodies directed by architectural noncoding RNA -- Chapter 9. Force-dependent remodeling of cell-to-cell adhesion through the regulation of phase separation -- Chapter 10. Neuronal RNA granules: Phase separation, dynamics, and higher brain functions -- Chapter 11. Liquid-liquid phase separation in structure and function of nuclear pore complex -- Chapter 12. Phase Separation Orchestrates Cancer Signaling: Biomolecular condensates as a promising target for cancer therapy -- Chapter 13. Regulatory interaction of intrinsically disordered regions of pathogenic proteins in neurodegenerative diseases -- Chapter 14. Functional properties of phase separation and intranuclear complex of FUS in the pathogenesis of ALS/FTLD -- Chapter 15. Functional responses of microglia to amyloid plaques -- Chapter 16. Emerging role of phage separation in COVID-19.
    Abstract: This book presents the latest cutting-edge research on phase separation. It discusses the benefits and risks of phase separation for living cells from the perspectives of physics, chemistry, biology, and medicine. Phase separation is a physico-chemical process that induces a single solution of solvent and intrinsically disordered proteins (IDPs) to separate into two phases, one phase containing only solvent and the other containing IDPs in the solvent. A key molecule in phase separation is the intrinsically disordered region (IDR) proteins (IDPs), mostly comprised of RNA-binding proteins (RBPs). One of the major roles of phase separation is to generate condensates, membrane-less organelles including stress granule, Cajal body, and nucleolus. Biological actions of phase separation in various aspects of science have received increasing attention in recent years. The book consists of four parts; Part I on physics and chemistry includes topics on structural biology of RBP FUS/TLS and chaperone for phase separation, computational approach of phase separation, and chemistry of G-quadruplex of DNA and RNA. Part II on molecular biology presents molecular mechanism of IDR sequence phase separation and potential cellular function of these labile fibers, formation of membrane-less organelles, and roles of noncoding RNAs in phase separation. Part III on biology covers topics from nuclear pore complex, developmental biology regarding force-dependent remodeling, and neurobiology and higher order brain functions. Finally, Part IV on medicine presents condensates and cancer therapy, pathogenesis of neurodegenerative diseases based on IDPs, and responses of microglia to amyloid. The last chapter highlights the latest topic on how the SARS-Cov-2 virus takes advantage of phase separation for its infections. This book brings together the studies of phase separation in each area in a single volume. The comprehensive approach provides new insights to the research and will benefit the readers by responding to the emerging needs for understanding phase separation.
    Type of Medium: Online Resource
    Pages: VIII, 318 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819948864
    DDC: 572
    Language: English
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    Keywords: Agriculture. ; Botany. ; Plant physiology. ; Agriculture. ; Plant Science. ; Plant Physiology.
    Description / Table of Contents: Chapter 1. Occurrence of salinity and drought stresses: status, impact and management -- Chapter 2. Multiple stresses is a big challenge for development of tolerant varieties: Shared and unique physiological responses -- Chapter 3. Physio-biochemical approaches for raising drought tolerance in plants: Recent progress and future perspectives -- Chapter 4. Physiological, biochemical and molecular responses to salt stress and seed priming approach to enhance salt tolerance in bread wheat -- Chapter 5. Drought and salinity stress: an overlapping osmotic resistance -- Chapter 6. Physiological and Post-Harvest Quality Changes of Horticultural Crops under salt stress -- Chapter 7. Conventional Breeding and Advance Approaches to Mitigate Drought and Salt Stress in Crop Plants -- Chapter 8. Strategies for improving tolerance to combined effect of drought and salinity stress in crops -- Chapter 9. Stress protectants in amelioration of abiotic stress: mechanism of action and potential role in sustaining oilseed and pulses productivity -- Chapter 10. Insights into drought and salinity stress tolerance in crop plant through various genomic approaches under changing climate -- Chapter 11. Strategies to improve drought and salinity tolerance in some cash crops through proteomics perspective -- Chapter 12. Insights in metabolomics responses to drought and salinity stress in crop plants -- Chapter 13. Transcriptional Regulatory Network Involved in Drought and Salt Stress Response in Rice -- Chapter 14. Advancement of omics approaches in understanding the mechanism of salinity tolerance in legumes -- Chapter 15. Speed Breeding: A budding technique to improve crop plants for drought and salinity tolerance.
    Abstract: This edited book is a comprehensive collection of scientific research on different plants under drought and salt stress conditions. The main focus of this book is to elaborate on the mechanisms being operative in plants under stress and how various biological factors mitigate the adverse effects for better plant productivity. This book covers all physiological, biochemical, and molecular mechanisms operating under drought and saline stresses. The current status and impact of drought and salinity on various crop plants have been elaborated on in different chapters. Agricultural lands are either turning barren or becoming more saline and drought-prone with increasing temperatures, decreasing water tables, untimely rainfall, and other environmental factors. In India, salt-affected soils occupy an area of about 6.73 million ha of which saline and sodic soils constitute roughly 40 and 60%, respectively. All these factors individually or cumulatively, affect the plant growth and development and hence, the crop productivity with the monetary loss. The inbuilt plant's ability with modified/acclimatized mechanisms has been described in various chapters with step-wise descriptions. The role of various plant growth-promoting agents including nano-particles, micro-organisms, metabolites or phytohormones, etc in mitigating adverse effects of drought and salinity has been explained precisely. Updated information on the use of speed breeding, proteomics, epigenetics, and transcriptomics in different crops along with high throughput technologies is included for the cross-talk of various network mechanisms. This book is helpful for the readers in knowing salinity and drought through the physiological, biochemical and genetic, and molecular levels to understand plant behaviour under stress conditions. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, plant physiology, biochemistry, forestry, and environmental sciences. National and international agricultural scientists and policymakers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XIX, 602 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819946693
    DDC: 630
    Language: English
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    Keywords: Plant physiology. ; Agronomy. ; Botanical chemistry. ; Plant Physiology. ; Agronomy. ; Plant Biochemistry.
    Description / Table of Contents: Ch 1. Melatonin discovery and divergent biosynthetic pathways in plant -- Ch 2. Melatonin detection and quantification techniques -- Ch 3. Melatonin-mediated regulation of germination, plant establishment and vegetative development -- Ch 4. Regulatory role of melatonin in flowering, fruit setting and ripening -- Ch 5. Regulatory role of melatonin in photosynthesis and respiration -- Ch 6. Phytohormonal cross-talk with melatonin in plant -- Ch 7. Interaction of melatonin with reactive oxygen species in plants -- Ch 8. Reactive Nitrogen Species (RNS) and Melatonin Interaction in Plant -- Ch 9. Diverse functional role of melatonin in post-harvest biology -- Ch 10. Regulatory role of melatonin in post-harvest management of vegetables and fruits -- Ch 11. Synergistic effect of melatonin in plant growth and development in stress mitigation -- Ch 12. Melatonin mediated regulation of growth, production and protection in forest plant species -- Ch 13. Melatonin: A promising tool against climate change and food security for better plant survival.
    Abstract: This book highlights the multifunctional role of the ubiquitous molecule, melatonin, in crop plants. The major focus of this edition is to provide detailed insights into morphophysiological, biochemical, and molecular responses of melatonin in the growth and development of the plant. The inception of melatonin as an animal hormone and the subsequent discovery of its multifaceted function in the animal system has triggered the research on this pineal gland hormone. During the last decade, the discovery, quantification and functional studies of melatonin as phytohormone has emerged at a rapid pace. Recently, this phyto-protectant has become an integral component of lab and field-based research on the mitigation of adverse effects of climate-driven abiotic stresses and postharvest biology and technology. The book explores various biosynthetic pathways and detection of melatonin covering its role in flowering, fruit development, photosynthesis, respiration, hormonal crosstalk, post-harvest biology and reactive oxygen species and nitrogen cycles. This book is of high interest to postharvest industries, horticulturists, scientists, researchers, and students. .
    Type of Medium: Online Resource
    Pages: XVII, 300 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819967452
    DDC: 571.2
    Language: English
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  • 42
    Keywords: Medicine Research. ; Biology Research. ; Genetics. ; Bioinformatics. ; Biomedical Research. ; Genetics and Genomics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1_Introduction to Pulmonary Diseases and OMICS approaches -- Chapter 2_Obstructive Pulmonary Diseases -- Chapter 3_COPD (Chronic Obstructive Pulmonar Diseases) -- Chapter 4_ Asthma -- Chapter 5_Other obstructive airway diseases like Bronchiectases, Focal airway narrowing -- Chapter 6_Restrictive Pulmonary Diseases (Common qualities and features with examples) -- Chapter 7_Interstitial Pulmonary fibrosis (IPF) -- Chapter 8_Sarcoidosis -- Chapter 9_ Other restrictive airway diseases like pneumonitis, pleural thickening -- Chapter 10_Vascular Diseases -- Chapter 11_Pulmonary hypertension -- Chapter 12_Pulmonary edema -- Chapter 13_ Other vascular diseases like Pulmonary Edema, Cor Pulmonale -- Chapter 14_Infectious Diseases -- Chapter 15_Tuberculosis -- Chapter 16_Cystic fibrosis -- Chapter 17_Pneumonia, COVID-19 and others -- Chapter 18_Neoplastic Diseases/Lung Cancer.
    Abstract: This book comprehensively reviews various omics approaches like genomics, proteomics, transcriptomics, and metabolomics for understanding pulmonary disease at molecular and systems levels. The initial chapters present the pathogenesis of major pulmonary diseases, namely, obstructive diseases, restrictive diseases, vascular diseases, infectious diseases, and neoplastic carcinoma. The book chapters provide current information about the role of the microbiome and applications of medical imaging, bioinformatics tools, and databases for diagnosis and designing treatment strategies against complex lung diseases. Further, the book discusses omics technologies to identify biomarkers for the early diagnosis and prognosis of pulmonary diseases. Finally, the book elucidates the multi-omics approaches and data integration using mathematical modeling for insights into the disease etiology towards improving the prognostics and predictive accuracy of disease phenotypes.
    Type of Medium: Online Resource
    Pages: XIII, 405 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819935055
    DDC: 610.72
    Language: English
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    Keywords: Plant physiology. ; Plant diseases. ; Botanical chemistry. ; Plant Physiology. ; Plant Pathology. ; Plant Biochemistry.
    Description / Table of Contents: Ch 1. Evolution of melatonin as an oxidative stress mitigator in plant -- Ch 2. Melatonin-mediated drought stress mitigation by modulation of physiological and biochemical responses in plants -- Ch 3. Reprogramming of salt stress under the influence of melatonin -- Ch 4. Mechanistic insights on melatonin-mediated heat stress regulation in plant -- Ch 5. Melatonin a key regulator of cold stress in plants -- Ch 6. Illustrating recent development in melatonin-heavy metal research in plant -- Ch 7. Melatonin in Nutrient use efficiency of regulation in crop plants -- Ch 8. Melatonin-mediated signalling and regulation of viral and bacterial diseases -- Ch 9. Explicating the role of melatonin in the mitigation of fungal diseases in plants -- Ch 10. Role of melatonin in management of stress tolerance of forest tree species -- Ch 11. Emerging role of melatonin in integrated management of crop pathogens -- Ch 12. Exploring Melatonin's Potential as an Alternative Strategy for Protecting Plants from Biotic Stresses.
    Abstract: This edited book highlights the multifunctional role of the ubiquitous molecule, melatonin in crop plants. The major focus of this edition is to provide a comprehensive insight into the key focus is on Melatonin mediated alleviation of abiotic stresses and pathogens infection. The inception of melatonin as an animal hormone and the subsequent discovery of its multifaceted function in the animal system has revolutionized the research on this penial hormone. During the last decade, the discovery, quantification and functional studies of melatonin as phytohormone has emerged at a rapid pace. Recently, this phyto-protectant has become an integral component of lab and field-based research on the mitigation of adverse effects of climate-driven abiotic stresses and postharvest biology and technology. The book explores melatonin mediated management of various abiotic stresses such as drought, salinity, heat and cold temperature. The book also focuses on role of melatonin in heavy metal stress, viral, bacterial, and fungal diseases, and, also contains chapter on melatonin facilitated nutrient use efficiency in plants. This book is of interest to postharvest industries, horticulturists, scientists, researchers, and students.
    Type of Medium: Online Resource
    Pages: XVI, 242 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819967414
    DDC: 571.2
    Language: English
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  • 44
    Keywords: Microbiology. ; Pharmacology. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Microbiology. ; Pharmacology. ; Medical Microbiology. ; Translational Research.
    Description / Table of Contents: 1. Microbial Diversity and Their Role in Human Health and Diseases -- Section I: Gut Microbes and Perspectives -- 2. Emerging Microbial Identification Technologies in the Era of Omics and Genome Editing -- 3. Gut Microbiome: Perspectives and Challenges in Human Health -- 4. Probiotics – A Healthy Treasure -- 5. Different Generations of Probiotics: An Effective Way to Restore Gut Homeostasis -- 6. Application Of Potential Microbial Biotechnology for Sustainable Human Health -- Section II: Emerging Technologies in Gut Microbiome Research -- 7. Emerging Technologies and Current Advances in Human Bacteriome Research -- 8. Emerging Microbial Technologies: Mitigating Challenges to Humanity -- 9. Modern Tools of Genome Engineering and Their Applications -- 10. Emerging Technologies to Investigate the Potential of Gut Microbiota in Human Health -- 11. Tools and Techniques for Exploring Hidden Microorganisms: A Potential Future of Human Health Diagnosis -- 12. Crispr-Cas Fundamentals and Advancements in Translational Biotechnology” -- Section III: Gut Microbiome and Metabolic Disorders -- 13. Microbiome and Human Health: From Dysbiosis to Therapeutic Interventions -- 14. Gut Microbiota and Its Role in Human Metabolic Disorders -- 15. Influence Of the Gut Microbiome on Cardiovascular Health and Hypertension -- 16. Role Of Microbiome in Reproductive Health: An Expanding Dimension -- 17. Role Of Bacteriocins in Modulation of Microbiome in Human Diseases -- 18. Emerging Role of Gut Microbiome in Cancer Immunotherapy -- 19. Microbial Secondary Metabolites: Targetting Tumors and Associated Challenges -- 20. Bacteria And Bacteria-Based Products in Cancer Therapy: Current Status and Future Advances -- 21. Communication With Gut Microbiota: An Emerging Strategy to Predict and Prevent Cancer -- 22. Insights in the Cross-Talk Between Microbiota-Gut-Brain Axis: A Focus On Alzheimers’s Disease -- Section IV: Association of Phages and Fungi with Gut Microbiome -- 23. Fungi As a Treasure Trove of Bioactive Compounds for Human Health -- 24. Reminiscing Phages in The Era of Superbugs -- 25. The Potential of Bacteriophages in Treating Covid-19 Associated Secondary Infections -- Section V: Diverse Roles of Microbiome -- 26. Role Of Microbes in Production of Vaccines -- 27. Microbial Induced Calcite Precipitation Approach Towards Sustainable Development -- 28. Microbial Functional Foods and Nutraceuticals -- 29. Synthesis of Nanoparticles by Microbes -- 30. Microbial Biopharmaceuticals in Urolithiasis Management and Treatment -- 31. Use Of Yeast In The Welfare Of Human and Their Applications -- 32. Photoautotrophic Microbes with Potential for A Super Health Food On This Planet -- 33 Autopsy and COVID-19 -- 34 COVID and their Impacts on Aquatic Systems: Is it a Solution for Environmental Resilience? .
    Abstract: This book examines the role of human microbiome in human health and diseases. The initial chapters present tools for genetic manipulation of gut microbiota and the therapeutic applications of engineered microbiota. They discuss the interaction between human microbiota and host in defining the prominent role of microbes in the development and progression of major human diseases. The book also summarizes the current applications and trends for the development, production and analytical characterization of recombinant therapeutic proteins in microbial systems. It also reviews the role of microbes in the production of vaccines and antibiotics. Further, the book presents bacterial products, including proteins, enzymes, immunotoxins and secondary metabolites, that target cancer cells and cause tumour regression. The chapters also discuss the critical role of gut microbiota dysbiosis in the pathogenesis of autoimmune disease and in bowel-related diseases. Towards the end, the book explores the role of intestinal microbiota in metabolic health and the pathogenesis of common metabolic disorders. It presents state-of-the-art insights into important aspects of United Nations—Sustainable Developmental Goal 3.
    Type of Medium: Online Resource
    Pages: XXII, 713 p. 55 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819931262
    DDC: 579
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Gynecology . ; Human physiology. ; Immunology. ; Biomedical Research. ; Gynecology. ; Human Physiology.
    Description / Table of Contents: Part I -- Chapter 1: Introduction -- Chapter 2: Recurrent Pregnancy Loss and Recurrent Implantation Failure -- Chapter 3: Immune System -- Chapter 4: Immunology of Pregnancy (Reproductive Immunology) -- Chapter 5: Diagnosis of Alloimmune factor -- Part II -- Chapter 6: Introduction -- Chapter 7: History of LIT -- Chapter 8: Mechanism of Action of LIT -- Chapter 9: Procedure of LIT -- Chapter 10: Safety of LIT -- Chapter 11: Controversies about LIT – REMIS Study -- Chapter 12: Cochrane Reviews & LIT -- Chapter 13: Recent Meta-analyses & LIT -- Chapter 14: Review of International studies of LIT -- Chapter 15: Case Studies -- Chapter 16: Future of LIT.
    Abstract: Recurrent Miscarriages (RM) & Implantation Failure (IF) have remained an enigma to clinicians and researchers. Even after ruling out all possible causative factors, 50-60% cases still remain “Unexplained’. A majority of these so called “Unexplained” cases are now found to have immunological basis. This book is going into the Immunological aspects of these clinical dilemmas, demystifying the role of Immunology and Immunotherapy in RM and IF. The authors have been working in the field of Reproductive Immunology and Immunotherapy for the last 25 years and they have come out with this book combining the international studies with their own experience. The purpose of writing this book is to provide a comprehensive treatise about Immunotherapy, so that it can become an acceptable modality of treatment in cases where it is needed and is effective. The book discusses the basics in Reproductive Immunology. The immunological changes occurring during pregnancy, the role of Cell mediated Immunity (T cells), Humoral Immunity including cytokines is explained. The normal immunological mechanisms protecting the embryo are highlighted and how these mechanisms are disturbed leading to RM and IF, is also explained. The first and the most discussed method of Immunotherapy is Lymphocyte Immunization Therapy (LIT). The book has given a complete overview of LIT, describing how it created euphoria when it was first introduced, how it gradually went into disrepute and how it is now making a comeback. As the authors have personal experience of LIT, the book gives a detailed and complete information about this active form of immunotherapy. The book has a special section on case studies where the authors have given some clinical case reports (including some of their own), who were treated for immunological factor in RM/IF and were treated with Immunotherapy. These cases can be a useful guide to the readers. The book will be useful not only for undergraduate and postgraduate students but also for clinicians in their practice and for researchers for review of developments in the field.
    Type of Medium: Online Resource
    Pages: XVIII, 147 p. 33 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811929601
    DDC: 571.96
    Language: English
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  • 46
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botanical chemistry. ; Food science. ; Plant physiology. ; Biotechnology. ; Plant Biochemistry. ; Food Science. ; Plant Physiology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Search of Sweeteners, their general classification, synthesis, and saccharide sweeteners plant - animal interphases -- Chapter 3. Molecular basis of sweetness and recent concepts, An ideal sweetener and saccharide and non-saccharide sweet principles qualifying it -- Chapter 4. Saccharide sweet (SS) principles, classification and structural and functional details of SS sweeteners and plants -- Chapter 5. Non saccharide super sweet principles, their general characteristics, outline of synthesis, classification, ecological significance and eco-friendly adherence -- Chapter 6. Perillartine (Mono-terpenoid) -- Chapter 7. Steviosides (Diterpenoids) -- Chapter 8. Triterpenoids -- Chapter 9. Hernandulcin: (Sesquiterpene) -- Chapter 10. Falvonoid Super Sweet Principles Dihydrochalcone -- Chapter 11. PHYLLODULCIN -- Chapter 12. Osladin, Polypodoside A, B, and C (Steroidal saponins) -- Chapter 13. Monatin:(Super Sweet Amino acid) -- Chapter 14. Super sweet and taste modifier proteins -- Chapter 15. Vegetal Taste modifiers -- Chapter 16. Eco-Physiological difference between sacchariferous sweet (SS) and non sacchariferous super sweet (NSSS) principles and Plants -- Chapter 17. Molecular approaches for the improvement of Non sacchariferous super sweet (NSSS) plants -- Chapter 18. Commercial Production of natural NSSS sweeteners-A concised sketch.
    Abstract: This book gathers the latest information on various kinds of natural, plant-based sweet and super sweet sweeteners. A book on alternative, natural sweeteners with zero or very few calories is extremely timely and useful, especially in light of the decreasing amount of cultivable land, ever-increasing demand for sucrose, and the well-known risks of sugar consumption. Every year, more than five million people die due to diabetes and diabetes-associated diseases like cardiovascular conditions, kidney disorders, liver cancer, etc. This book describes the use of natural non-saccharide super sweet (NSSS) principles to avoid such maladies. Readers will gain an in-depth understanding of various sweeteners, the molecular basis of sweetness, sweeteners’ general classification, plant sources, etc. In turn, the book focuses on the propagation, cultivation and conservation of NSSS plants (NSSSP) and extraction of super sweet principles and granting of Generally Recognised As Safe (GRAS) certificates for sweeteners. The closing chapter describes the eco-physiological difference between sacchariferous sweet and non-sacchariferous super sweet plants and principles. This book will be of great interest to researchers, professors, graduate students and practitioners in the fields of food science, nutrition, ayurveda, plant physiology, unani, chemotaxonomy, naturopathy, biochemistry and plant breeding. It will also be of interest to industry and alternative sweetener manufacturers.
    Type of Medium: Online Resource
    Pages: XXIX, 773 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789813363502
    DDC: 572.2
    Language: English
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  • 47
    Keywords: Medicine Research. ; Biology Research. ; Cancer. ; Technology Sociological aspects. ; Genomics. ; Biomedical Research. ; Cancer Biology. ; Emerging Technologies. ; Genomics.
    Description / Table of Contents: Chapter 1. Introduction to emerging technologies in biomedical sciences -- Chapter 2. Bioprospecting : boon or curse -- Chapter 3. Growing need for interdisciplinary biomedical research -- Chapter 4. Interplay between theory and experiment : a future approach for biomedical research -- Chapter 5.past, present and future perspectives of biomedical innovation in india -- Chapter 6. Systems biology approaches to study disease comorbidities -- Chapter 7. Bioinformatics the interactome of multidisciplinary approaches -- Chapter 8. Role of artificial intelligence in diagnosis of infectious diseases -- Chapter 9. Dna digital data storage breakthroughs in biomedical research. Chapter 10. Biomedical applications cloud-based iot -- Chapter 11. Next generation sequencing in cancer research -- Chapter 12. Crispr: genome editing and beyond -- Chapter 13. Omics in tuberculosis diagnosis : today and tomorrow -- Chapter 14. Advances in proteomic approaches for chronic kidney disease -- Chapter 15. 3 d bioprinting of tissues and organs : a new paradigm in regenerative medicine and biomedical engineering -- Chapter 16. Virtual planning, rapid prototyping and 3-d printing in orthopedic surgery -- Chapter 17. Tissue chips: contemporary applications and advancementstissue chips: contemporary applications and advancements -- Chapter 18. Flow cytometry for measuring neutrophil function -- Chapter 19. Flow cytometer for understanding genome size variation among medicinal herbs and non-edible oil trees of northeast india -- Chapter 20. Raman spectroscopy applications for bacterial detection -- Chapter 21. Microfluidic point-of-care diagnostic devices: a contemporary relevance. Chapter 22. Fluorescent dots for breast cancer management -- Chapter 23. Molecular mimicry : unravelling the role of autoantibodies in autoimmune diseases and infertility -- Chapter 24. Strategies of vaccine development -- Chapter 25. Preclinical models of intimal hyperplasia and restenosis to predict clinical events and develop novel therapies -- Chapter 26. Sphingolipids : a roadmap from biomarker identification to clinical application -- Chapter 27. Future of gastrointestinal endoscopy -- Chapter 28. Beating heart in a box : the future of cardiac transplant -- Chapter 29. The journey of coronary stent technology -- Chapter 30. Materiovigilance in clinical surgery.
    Abstract: This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.
    Type of Medium: Online Resource
    Pages: XIII, 505 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643453
    DDC: 610.72
    Language: English
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  • 48
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Microbial genetics. ; Industrial microbiology. ; Microbiology. ; Biomedical Research. ; Medical Microbiology. ; Microbial Genetics. ; Industrial Microbiology. ; Microbiology.
    Description / Table of Contents: Chapter 1. Epidemiology of Oral Squamous Cell Carcinoma in Indian Scenario -- Chapter 2. Risk factors for Oral Squamous Cell Carcinoma in the Indian population -- Chapter 3. Molecular Carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 4. Inflammation and Infection in Cancer -- Chapter 5. Role of Inflammation and Infection in Oral Squamous Cell Carcinoma -- Chapter 6. Normal Microbiome of Oral cavity -- Chapter 7. Oral Microbiome in Oral Squamous Cell Carcinoma -- Chapter 8. Microbial Dysbiosis in Oral Squamous Cell Carcinoma -- Chapter 9. Bacteria induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 10. Virus induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 11. Fungi: Culprits or Bystanders in Oral Squamous Cell Carcinoma -- Chapter 12. Microbial ‘omics’ in Oral Squamous Cell Carcinoma -- Chapter 13. Implications and Future perspectives.
    Abstract: This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention. The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like for this area of research. The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.
    Type of Medium: Online Resource
    Pages: XIII, 172 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811905926
    DDC: 610.72
    Language: English
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  • 49
    Keywords: Stress (Physiology). ; Plants. ; Plant physiology. ; Plant biotechnology. ; Plant genetics. ; Plant Stress Responses. ; Plant Physiology. ; Plant Biotechnology. ; Plant Genetics.
    Description / Table of Contents: Chapter 1. Morphological, architectural and biochemical modifications of cereal crops during abiotic stress -- Chapter 2. Cereal physiology, flowering and grain yield under salinity and drought stress -- Chapter 3. Physiology, flowering and grain yield under abiotic stress imposed by heavy metals -- Chapter 4. Priming effect in developing abiotic stress tolerance in cereals through metabolome reprograming -- Chapter 5. Understanding abiotic stress tolerance in cereals through genomics and proteomics approaches -- Chapter 6. Metabolome analyses in response to diverse abiotic stress -- Chapter 7. Metabolomic profiling of different cereals during biotic and abiotic stresses -- Chapter 8. Plant breeding strategies for abiotic stress tolerance in cereals -- Chapter 9. Transgenic strategies to develop abiotic stress tolerance in cereals -- Chapter 10. Genetically engineered cereals tolerant to abiotic stress -- Chapter 11. Genome editing and CRISPR-Cas technology for enhancing abiotic stress tolerance in cereals -- Chapter 12. Abiotic stress tolerance in cereals through genome editing -- Chapter 13. Varietal physiology, metabolic regulation and molecular responses of rice genotypes to diverse environmental stresses -- Chapter 14. Breeding and Omics Approaches to Understand Abiotic Stress Response in Rice -- Chapter 15. Genomics and transcriptomics approaches to understand abiotic stress response in rice -- Chapter 16. Biochemical and molecular mechanism of wheat to diverse environmental stresses -- Chapter 17. How microRNAs Regulate Abiotic Stress Tolerance in Wheat? A Snapshot -- Chapter 18. Molecular-genetic studies, breeding and genomics-based approaches to develop abiotic stress tolerance in sorghum -- Chapter 19. MicroRNAs shape the Tolerance Mechanisms against Abiotic Stress in Maize -- Chapter 20. Transcriptome, proteome and metabolome profiling for abiotic stress tolerance in maize and barley -- Chapter 21. Omics tools to understand abiotic stress response and adaptation in rye, oat and barley -- Chapter 22. Genomic tools and proteomic determinants for abiotic stress tolerance in pearl millet (Pennisetum glaucum) and foxtail millet (Setaria italica L.) -- Chapter 23. Advancement in Omics Technologies for Enhancing Abiotic Stress Tolerance in Finger millet -- Chapter 24. Buckwheat (Fagopyrum esculentum) response and tolerance to abiotic stress -- Chapter 25. Abiotic Stress Response and Adoption of Triticale.
    Abstract: The edited book highlights various emerging Omics tools and techniques that are currently being used in the analysis of responses to different abiotic stress in agronomically important cereals and their applications in enhancing tolerance mechanism. Plants are severely challenged by diverse abiotic stress factors such as low water availability (drought), excess water (flooding/ waterlogging), extremes of temperatures (cold, chilling, frost, and heat), salinity, mineral deficiency, and heavy metal toxicity. Agronomically important cereal crops like Rice, Wheat, Maize, Sorghum, Pearl Millet, Barley, Oats, Rye, Foxtail Millets etc. that are the major sources of food material and nutritional components for human health are mostly exposed to abiotic stresses during the critical phases of flowering and grain yield. Different Omics platforms like genomics, transcriptomics proteomics, metabolomics and phenomics, in conjunction with breeding and transgenic technology, and high throughput technologies like next generation sequencing, epigenomics, genome editing and CRISPR-Cas technology have emerged altogether in understanding abiotic stress response and strengthening defense and tolerance mechanism of different cereals. This book is beneficial to different universities and research institutes working with different cereal crops in the areas of stress physiology, stress-associated genes and proteins, genomics, proteomics, genetic engineering, and other fields of molecular plant physiology. The book can also be used as advanced textbook for the course work of research and master’s level students. It will be of use to people involved in ecological studies and sustainable agriculture. The proposed book bring together the global leaders working on environmental stress in different cereal crops and motivate scientists to explore new horizons in the relevant areas of research.
    Type of Medium: Online Resource
    Pages: IX, 615 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811901409
    DDC: 581.788
    Language: English
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  • 50
    Keywords: Medicine Research. ; Biology Research. ; Therapeutics. ; Medical informatics. ; Translational Research. ; Therapeutics. ; Health Informatics.
    Description / Table of Contents: Introduction: The importance of regionalized management of medicine -- Alcohol use disorders -- Public-private partnerships management in health care: The Portuguese experience -- Management of Clinical Precision Medicine -- Artificial Intelligence in medical management -- Advanced Demand Forecasting and Inventory Management Methods in Hospital Pharmacy -- Clinical Application of Cell-Based Therapies Opportunities and Challenges -- Management of Next-Generation Sequencing (NGS) in Precision Medicine -- Exploration on the Reform of County Medical Integration -- The Regionalization of Medical Management: The Practice and Exploration of Established Fudan-Minhang Medical Alliance -- Bed-occupancy management and hospital planning: a handbook -- Management of severe childhood pneumonia in low resource setting -- The role of mitochondrial-targeted antioxidant, MitoQ, in neurodegenerative disease -- Progression of mitochondria research for clinical potentials -- DNA methylation in pulmonary inflammatory diseases -- Synthetic lethality and lung cancer.
    Abstract: The Book mainly focuses on various aspects of regionalized management of medicine, related with updates of new biotechnology, application of therapeutic strategy, and understanding of disease-associated molecular mechanisms. The book also discusses how medical informatics, systems analysis, database sharing, and artificial intelligent can be applied for improving the quality of hospital managements, disease therapies, regional collaborations, and medical services. This book serves as a professional reference book to clinicians and experts who are interested in medical informatics and artificial intelligence for diseases therapies and therapeutic strategy, better systems analysis and database sharing, and more efficient regional collaborations and medical services.
    Type of Medium: Online Resource
    Pages: X, 226 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811678936
    Series Statement: Translational Bioinformatics, 17
    DDC: 610.72
    Language: English
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  • 51
    Keywords: Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Abstract: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Type of Medium: Online Resource
    Pages: XV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676062
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Toxicology. ; Cytology. ; Biomedical Research. ; Biomedical Devices and Instrumentation. ; Toxicology. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Historical and Technological Background to Organs-on-a-Chip -- Chapter 2. Applications of microfluidics -- Chapter 3. Microfluidics based Organ-on-a-chip for cell biology studies -- Chapter 4. Microfluidics in Chemical biology -- Chapter 5. Role of microfluidics in drug delivery -- Chapter 6. Microfluidics in drug discovery -- Chapter 7. Microfludic based sensors -- Chapter 8. Background and Organs-on-a-Chip -- Chapter 9. Culture and co-culture of cells for multi organ on chip -- Chapter 10.Cells and organs on a chip in biomedical sciences -- Chapter 11. Futuristic aspects of organ on a chip -- Chapter 12. Development of Human on a chip -- Chapter 13. Multi-organ on a chip for personalized medicine -- Chapter 14. Development and application of Microfluids in organoid formation -- Chapter 15. Liver on a chip -- Chapter 16. Placenta on Chip: A Modern approach to probe feto-maternal interface -- Chapter 17. Microfluidic retina-on-chip -- Chapter 18. Heart on a chip -- Chapter 19. Kidney on a chip -- Chapter 20. Lungs on a chip -- Chapter 21. Brain on a chip -- Chapter 22. Skin on a chip -- Chapter 23. Organs-on-a-chip in preclinical studies -- Chapter 24. Application of organ on chip in blood brain barrier model -- Chapter 25. Multi organs on a chip in disease modeling -- Chapter 26. Prospects of Medical device on a chip -- Chapter 27. Lab on a chip for precision Medicine -- Chapter 28. Tumour-on-a-chip : Perfusion systems to model the extracellular breast tumour microenvironment:from tumour progression to metastasis formation -- Chapter 29. Building Human In Vitro 3D Models to Replace Animal Studies: During Drug Discovery Reearch: Scientific, Ethical and Regulatory Considerations.
    Abstract: This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
    Type of Medium: Online Resource
    Pages: IX, 717 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913792
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Drugs Design. ; Pharmaceutical chemistry. ; Genomics. ; Bioinformatics. ; Biomedical Research. ; Structure-Based Drug Design. ; Pharmaceutics. ; Genomics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management.
    Abstract: This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.
    Type of Medium: Online Resource
    Pages: XII, 599 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692321
    DDC: 610.72
    Language: English
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  • 54
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botanical chemistry. ; Nanobiotechnology. ; Plant physiology. ; Green chemistry. ; Agricultural biotechnology. ; Nanotechnology. ; Food science. ; Plant Biochemistry. ; Nanobiotechnology. ; Plant Physiology. ; Green Chemistry. ; Agricultural Biotechnology. ; Food Nanotechnology.
    Description / Table of Contents: Chapter 1. Emerging trends of Nanoparticles in Sustainable Agriculture: Current and Future Perspectives -- Chapter 2.Nanoparticles in Plant Disease Management -- Chapter 3.Proteomics of Plant Nanoparticles Interaction Mechanism -- Chapter 4. Importance of the secondary metabolites and biological parameters modification by metallic, oxides, and carbon-based nanomaterials over forage plants -- Chapter 5. Polymer-based nanoparticles (NPs): A promising approach for crops productivity -- Chapter 6.Plant mediated eco-friendly synthesis of platinum nanoparticles and their applications -- Chapter 7.Foliar Application of Metallic Nanoparticles on Crops Under Field Conditions -- Chapter 8.Phytotoxic effects of nanoparticles and defense mechanisms in plants -- Chapter 9.Plant Molecular Responses to Nanoparticle Stress -- Chapter 10. Nanoelicitation: A Promising and Emerging Technology for Triggering the Sustainable In Vitro Production of Secondary Metabolites in Medicinal Plants -- Chapter 11. Nanomaterials as unique carriers in agricultural practices for plant growth and development: A state of current knowledge -- Chapter 12. Nanotechnologies and Sustainable agriculture for Food and Nutraceutical production: An Update -- Chapter 13. Green synthesis of plant assisted manganese-based nanoparticles and their various applications -- Chapter 14.Biogenic synthesis of lead-based nanoparticles and their recent applications.
    Abstract: This book explores the interactions between nanomaterials/nanoparticles and plants and unveils potential applications. The chapters emphasize the implications of nanoparticles in cross-discipline approaches, including agricultural science, plant physiology, plant biotechnology, material science, environmental science, food chemistry, biomedical science, etc. It presents recent advances in experimental and theoretical studies and gives in-depth insights into the interaction between nanoparticles and plant cells. In addition, it discusses the potential applications and concerns of nanoparticles comprehensively. The research field of plant nanotechnology has great potential within plant sciences and agriculture and the related research is getting increased at present. The study of plant nanotechnology receives an advantage from the great progress of nanotechnology in biomedical sciences particularly the well-development of a variety of biocompatible nanoparticles (NPs) and advanced analytical techniques. Nowadays, although some NPs have been applied in the studies of plant and agronomic sciences, the knowledge regarding physiology and underlying mechanisms within the plant cell remains limited. This book offers a critical reference for students, teachers, professionals, and a wide array of researchers in plant science, plant physiology, plant biotechnology, material science, environmental science, food chemistry, nanotechnology, and biomedical science. It could also benefit the related field of plant nanotechnology for designing and organizing future research. .
    Type of Medium: Online Resource
    Pages: VII, 426 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811925030
    DDC: 572.2
    Language: English
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    Keywords: Immunology. ; Diseases Causes and theories of causation. ; Autoimmunity. ; Medicine Research. ; Biology Research. ; Immunology. ; Pathogenesis. ; Autoimmunity. ; Biomedical Research.
    Description / Table of Contents: Part I: OVERVIEW OF INFECTIOUS MICROORGANISMS & MICROBIOTA IN INDUCING AUTOIMMUNIT -- Chapter 1. The Concept of Infection Triggered autoimmunity -- Chapter 2. The interaction of gut microbiota with immune system and their effects on immune cell development and function -- Chapter 3. The Link between gut microbiota and autoimmune diseases -- Chapter 4. The factors influencing gut microbiota in autoimmune diseases -- PART II: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE LIVER DISEASES -- Chapter 5. Microorganisms in pathogenesis and management of Autoimmune hepatitis (AIH) -- Chapter 6. Microorganisms in pathogenesis and management of Primary Biliary Cholangitis -- Chapter 7. Microorganisms in pathogenesis and management of Primary biliary cholangitis -- PART III: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF SKIN AUTOIMMUNE DISEASES -- Chapter 8. Microorganisms in pathogenesis and management of Psoriasis -- Chapter 9. Microorganisms in pathogenesis and management of Vitiligo -- Chapter 10. Microorganisms in pathogenesis and management of Scleroderma (systemic sclerosis) -- Chapter 11. Microorganisms in pathogenesis and management of Atopic Dermatitis -- Chapter 12. Microorganisms in pathogenesis and management of Pemphigus Vulgaris -- Chapter 13. Microorganisms in pathogenesis and management of Bullous pemphigoid -- PART IV: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE THYROID DISEASES -- Chapter 14. Microorganisms in pathogenesis and management of Graves's Disease -- Chapter 15. Microorganisms in pathogenesis and management of Hashimoto's Thyroiditis -- PART V: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE RHEUMATIC DISEASES -- Chapter 16. Microorganisms in pathogenesis and management of Rheumatoid Arthritis (RA) -- Chapter 17. Microorganisms in pathogenesis and management of Spondyloarthritis -- Chapter 18. Microorganisms in pathogenesis and management of Ankylosing spondylitis (AS) -- Chapter 19. Microorganisms in pathogenesis and management of Psoriasis Arthritis (PsA) -- Chapter 20. Microorganisms in pathogenesis and management of Systemic Lupus Erythematosus (SLE) -- Chapter 21. Microorganisms in pathogenesis and management of Sjogren’s syndrome -- Chapter 22. Autoimmune Diseases Associated with Chikungunya Infection -- PART VI: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF IDIOPATHIC INFLAMMATORY MYOPATHIES -- Chapter 23. Microorganisms in pathogenesis and management of dermatomyositis (DM) and polymyositis (PM) -- Chapter 24. Microorganisms in pathogenesis and management of necrotizing autoimmune myopathy (NAM) and inclusion body myositis (IBM).
    Abstract: This book in the two volume set provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting into autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases. Contributions in the book focuses on the role of microbiota/probiotics and their distinct mechanisms exerted in management of autoimmune liver, skin, thyroid, rheumatic and myopathic diseases. This could help in better understanding to design therapeutic strategies that can be deployed to prevent these autoimmune diseases. The book has an interdisciplinary appeal and scholars with an interest immunology, medical microbiology and nutritional sciences will value its contribution. Overall, the book gives a new dimensions and insight in the aspects of microbial role in autoimmune disease pathogenesis and therapeutic aspects.
    Type of Medium: Online Resource
    Pages: XIX, 680 p. 26 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811919466
    DDC: 571.96
    Language: English
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    Keywords: Botanical chemistry. ; Plant physiology. ; Plant diseases. ; Plant ecology. ; Plant Biochemistry. ; Plant Physiology. ; Plant Pathology. ; Plant Ecology.
    Description / Table of Contents: Chapter 1. Signal transduction of brassinosteroids under abiotic Stresses -- Chapter 2. Plant proteomics and metabolomics investigations in regulation of brassinosteroid -- Chapter 3. Cross talk between brassinosteroids and nitric oxide regulate plant improvement during abiotic stress -- Chapter 4. Interaction between brassinosteroids and hydrogen peroxide networking signal molecules in plantsInteraction between brassinosteroids and hydrogen peroxide networking signal molecules in plants -- Chapter 5. Brassinosteroids and strigolactone signaling in plants -- Chapter 6. Mechanism associated with brassinosteroids crosstalk with gibberellic acid in plants -- Chapter 7. Brassinosteroids and ethylene mediated cross talk in plant growth and development -- Chapter 8. Interplay of brassinosteroids and auxin for understanding of signalling pathway -- Chapter 9. Brassinosteroids crosstalk with ABA under stress condition -- Chapter 10. Cross talk between brassinosteroids and cytokinins in relation to plant growth and developments -- Chapter 11. Role of brassinosteroids and its crosstalk with other phytohormone in plant responses to heavy metal stress -- Chapter 12. Mechanism associated with brassinosteroids mediated detoxification of pesticides in plants -- Chapter 13. Glyphosate: is brassinosteroids application a remedy? -- Chapter 14. The production of high-value secondary metabolites through hairy root transformation in the presence of brassinosteroids -- Chapter 15. Role of Brassinosteroids in Protein Folding Under High Temperature Stress -- Chater 16. Molecular mechanism of Brassinosteroids in boosting crop yield.
    Abstract: This book presents the state of the skill of understanding brassinosteroids (BRs) signaling plus crosstalk with phytohormone and their association in plant adaptation to abiotic stresses comprising physiological, biochemical, and molecular developments. Due to progressively adverse environmental conditions and scarce natural resources, high-efficient crops have become more important than ever. For the successful improvement of stress-tolerant plants, it is vital to understand the precise signaling appliances that plants practice to abide stresses as well as how much these mechanisms are convinced by phytohormone. However, it is also debatable on which step plants can attain brassinosteroids (BRs) signaling from an evolutionary viewpoint. BRs are involved in modulating a large array of important functions throughout a plant’s life cycles. BRs are considered as one of the most important plant steroidal hormones that show a varied role in observing a wide range of developmental practices in plants. Our grip on brassinosteroids signaling has quickly extended over the past two decades, owing in part to the isolation of the constituents intricate in the signal transduction trail. The book proposes a useful guide for plant researchers and graduate students in connected areas. .
    Type of Medium: Online Resource
    Pages: XXV, 295 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811657436
    DDC: 572.2
    Language: English
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    Keywords: Agronomy. ; Plant diseases. ; Agricultural biotechnology. ; Agricultural genome mapping. ; Plant physiology. ; Agronomy. ; Plant Pathology. ; Agricultural Biotechnology. ; Agricultural Genetics. ; Plant Physiology.
    Description / Table of Contents: Chapter 1. Potato Pests and Diseases: A Global Perspective -- Chapter 2. Phytosanitary Standards and International Exchange of Potato -- Chapter 3. Fungicide Resistance: Threats and Management Approaches -- Chapter 4. Role of Plant Nutrition in Disease Development and Management -- Chapter 5. Secondary Metabolites of Microbials as Potential Pesticides -- Chapter 6. Advances and Approaches in Mitigating Bacterial Diseases of Potato -- Chapter 7. Advances in Management of Late Blight of Potato -- Chapter 8. Role of Genetic Resources in Management of Potato Pests and Diseases -- Chapter 9. Biology and Management of Aphids Infesting Potato -- Chapter 10. Biology and Management of Whiteflies in Potato Crops -- Chapter 11. Biology and Management of Nematodes in Potato -- Chapter 12. Potato Viruses and Their Management -- Chapter 13. Serological and Molecular Diagnosis of Potato Viruses: An Overview -- Chapter 14. Pesticide Residues and International Regulations -- Chapter 15. RNA Interference: A Versatile Tool to Augment Plant Protection Strategies in Potato -- Chapter 16. New Chemistry Pesticides for Management of Potato Pests -- Chapter 17. Genome Editing Prospects to Develop Disease/Pest Resistant Potato Varieties -- Chapter 18. Biological Suppression of Insect Pests of Potato -- Chapter 19. Bio-intensive Management of Fungal Diseases of Potatoes -- Chapter 20. Use of Green Chemicals in Pest and Disease Management -- Chapter 21. Management of Major Fungal and Fungal-Like Soil-borne Diseases of Potato.
    Abstract: This book covers the important diseases and pests of potato which are of global significance. The pests and diseases in potato lead to huge economic losses by reducing the yield and quality of the produce. This book describes major pests and diseases in detail with particular emphasis on the latest developments with respect to their biology, ecology, and management. It highlights the importance of virus infection for seed potato production and diagnostic symptoms, along with management guidelines. The book brings forth tips for judicious use of pesticides for sustainable potato production and management of pesticide resistance. Use of novel approaches such as RNA interference, genome editing, and other genomic resources for drug designing in diseases and pest management is also emphasized in the book. This book is of interest to teachers, researchers, extension workers, potato growers, and policy makers. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture and plant pathology. National and international agricultural scientists and policy makers will also find this to be a useful read. .
    Type of Medium: Online Resource
    Pages: XVI, 540 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676956
    DDC: 630
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Food science. ; Nanotechnology. ; Biomedical Research. ; Food Science. ; Food Engineering. ; Food Nanotechnology.
    Description / Table of Contents: Chapter 1. Chapter 1. Food packaging industry - An introduction -- Chapter 2. Toward Smarter Food Packaging -- Chapter 3. Novel packaging development, assessment and authentication using smart technologies, non-invasive biometric sensory tools, and artificial intelligence -- Chapter 4. Biodegradable packaging materials and techniques to improve their performance -- Chapter 5. Smart Freshness Indicator for Animal Based Products Packaging - Current Status.-Chapter 6. Packaging of dairy products-Emerging strategies -- Chapter 7. Functional packaging materials for fishery products applications -- Chapter 8. Edible films and coatings: Major challenges and potential applications in food Packaging: A Review.-Chapter 9. Role of sensors to improve food/beverage packaging -- Chapter 10. Functional nanomaterials for food packaging applications -- Chapter 11. Rules and regulations related with packaging.
    Abstract: This book reviews the science and technology of food packaging and covers the potential innovations in the food packaging sector. At the same time, it highlights the issues and prospects for linking the laboratory research to the market. In addition to typical packaging requirements such as food quality, shelf life, protection, communication, and marketing, the book emphasizes the need for novel packaging materials, including biodegradable packaging for a variety of food products. A wide range of food products has been kept in focus and includes animal-based food products such as dairy products and sea foods. The book presents the next level of packaging solutions i.e., smart packaging with the applications of potential tools such as intelligent and active packaging, and includes the latest research on emerging digital technologies for packaging development, assessment, and acceptability. It further highlights the strategies including blends, reinforcing agents, cold plasma, UV light applications, chemical, and enzymatic methods and explores the new opportunities leading to improvement in the packaging performance. Smart freshness indicator applications, including gas and time-temperature indicators for quality and safety of packaged products, have been covered in detail. The book also includes the functional characteristics of edible films and coatings, including their bioactive characteristics. Finally the book presents the rules and regulation related to packaging.
    Type of Medium: Online Resource
    Pages: XI, 286 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811671968
    DDC: 610.72
    Language: English
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  • 59
    Keywords: Botanical chemistry. ; Agriculture. ; Plant diseases. ; Plant physiology. ; Plant biotechnology. ; Plant genetics. ; Plant Biochemistry. ; Agriculture. ; Plant Pathology. ; Plant Physiology. ; Plant Biotechnology. ; Plant Genetics.
    Description / Table of Contents: Chapter 1. Cadmium Contamination in Agricultural Soils and Crops -- Chapter 2. Intraspecific Variations in Cadmium Accumulation Capacity of Crops and Application of Pollution-safe Cultivar -- Chapter 3. Cultivar-dependent Cadmium Uptake and Translocation of Water Spinach and Its Stability -- Chapter 4. The Effects of Rhizosphere Properties on Shoot Cd Accumulation of Water Spinach -- Chapter 5. A Decisive Role of Roots on Shoot Cd Accumulation of Water Spinach -- Chapter 6. Subcellular and Chemical Mechanisms Affecting the Cultivar-dependent Cd Accumulation of Ipomoea aquatica Forsk -- Chapter 7. Breeding of New Cultivar of Water Spinach with Low Shoot Cd and Pb Accumulations -- Chapter 8. Differences of Cd-induced Gene Expressions between Low- and High-Cd Accumulating Cultivars of Water Spinach: a Case Using Suppression Subtractive Hybridization (SSH) Method -- Chapter 9. Comparative Transcriptome and MicroRNAs Analyses between Low- and High-Cd Accumulating Cultivars of Water Spinach.-Chapter 10. Perspectives on the Marker-assisted Breeding of the Cd-PSCs.
    Abstract: The cadmium (Cd) contamination has raised increasingly global concern on food safety. The book was composed to bring comprehensive and valuable thoughts about the food safety management against heavy metal contamination. In this book, current status of cadmium contamination in agricultural soils and crops is systematically summarized. In order to reduce the risk of Cd pollution in crops, Cd pollution-safe cultivar (Cd-PSC) strategy, i.e. identifying, breeding and applying the cultivars with particularly low Cd accumulation capacity in edible parts even when grown in Cd contaminated soil, is proposed as a most effective, low-cost and environmental-friendly method for minimizing Cd pollution in crops. To describe the framework of the Cd-PSC strategy, a series research results on water spinach (Ipomoea aquatica Forsk) are summarized as a typical case. The latest findings about the Cd-PSCs of water spinach, including cultivar variation in shoot Cd accumulation, identification and verification of low- and high-Cd accumulating cultivars, stability of Cd accumulation capacity at the cultivar level, biochemical and molecular mechanisms of the cultivar-dependent Cd uptake, transfer and accumulation, breeding methods for improving Cd-PSCs, and so on, have been covered. This book will provide valuable theoretical and practical understandings for controlling Cd pollution in crops grown on agricultural soils with known or unknown risk of Cd contamination.
    Type of Medium: Online Resource
    Pages: XVII, 211 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811677519
    DDC: 572.2
    Language: English
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  • 60
    Keywords: Medicine Research. ; Biology Research. ; Forensic sciences. ; Toxicology. ; Biomedical Research. ; Forensic Science. ; Toxicology.
    Description / Table of Contents: 1 Forensic Dna Analysis: A Powerful Investigative Tool -- 2 “Crime Scene Management Within Forensic Science-Forensic Techniques For Criminal Investigations -- 3 Small Size, Big Impact: Insects For Cadaver Examination -- 4 Dermatoglyphics & Other Impressions: Deciphering The Potential Of A Unique Hominid Niche -- 5 Postmortem Toxicology: A facet of drugs of expedites crimes -- 6 Forensic Biology: A Passport For Biological Evidence -- 7 Sexual offences: Recent methods of Investigation -- 8 Investigation Of Disaster Victim Identification -- 9 Review On Clinical Forensic Medicine -- 10 Firearms and Ammunitions: A sentient approach in criminal investigation -- 11 Digital and Cyber Forensics: A Contemporary evolution in Forensic Sciences -- 12 Fire Investigation: Arson Or Accidental -- 13 Psychological Evaluations: An Indoor game of Criminal Minds -- 14 Competence of Evidences: A Pragmatic Approach in Court of Law -- 15 Penology: A friend or foe for criminal justice system -- 16 Chain Of Custody: Scaling The Investigation To The Event. .
    Abstract: This book, the second volume of Crime Scene Management in Forensic Sciences, reviews the role and impact of forensic evidence in criminal investigations. It also addresses the importance of post mortem examination in criminal cases. The book investigates the use of insects and arthropods to estimate post mortem intervals during forensic investigations. Further, it discusses the physiological effects of xenobiotics at the time of death, based on their concentration and distribution in the body at autopsy. Importantly, it also discusses digital forensic investigation, which can be used for the analysis of digital evidence produced at a court of law. Lastly, it defines the structure and legal framework of these forensic evidences for the effective administration of the criminal justice system. It is an excellent source of information for forensics scientists and legal professionals.
    Type of Medium: Online Resource
    Pages: VIII, 418 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811666834
    DDC: 610.72
    Language: English
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  • 61
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Industrial microbiology. ; Bioinformatics. ; Synthetic Biology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Industrial Microbiology. ; Computational and Systems Biology. ; Synthetic Biology.
    Description / Table of Contents: Part 1 Introduction to Microbial Engineering -- 1 Exploring the Potential of Microbial Engineering: The Prospect, Promise and Essence -- Part 2 Microbial Engineering Approaches -- 2 Role of System Biology in Microbial System -- 3 Synthetic Biology: Refining Human Health -- 4 Probiotic Engineering: A focus on Inflammatory Bowel Disease -- 5 Engineering microbes for smart diagnostics & Lab on Chip -- 6 Bacteriophage and Virus Engineering -- 7 CRISPR Technologies: A tool for Engineering Microbes -- Part 3 Health Benefits -- 8 Recombinant Vaccines: The Revolution Ahead -- 9 Microbe-Host Metabolic Interaction- Probiotic Approach -- 10 Designer Microbes: Oncotherapy approach -- 11 The human gut microbiome in health, disease and therapeutics -- 12 Use of Engineered Bacteria for Production of Green Chemicals & Pharmaceuticals -- 13 Fat Fighting Microbes. Part 4 Innovation & Translation -- 14 Scale-up of engineering strain for industrial applications -- 15 Affordable therapeutics through Engineered Microbes -- 16 COVID-19: Lesson Learnt from Diagnostics to therapeutics. .
    Abstract: This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.
    Type of Medium: Online Resource
    Pages: XI, 374 p. 45 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811939792
    DDC: 610.72
    Language: English
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  • 62
    Keywords: Medicine Research. ; Biology Research. ; Food science. ; Agriculture. ; Biomedical Research. ; Food Science. ; Agriculture.
    Description / Table of Contents: Chapter 1. Millets-an Overview -- Chapter 2. Millet Cultivation an Overview -- Chapter 3. Millet Storage and Pest Management -- Chapter 4. Major Millets Processing -- Chapter 5. Minor millet processing and its impacts on composition -- Chapter 6. Chemistry of Millets: Major and Minor Constituents -- Chapter 7. Nutritional properties of millets: neglected cereals with potentials to combat malnutrition -- Chapter 8. Post-harvest Treatments and Storage of millets -- Chapter 9. Millet Milling Technologies -- Chapter 10. Effect of Processing on Functional Characteristics, Physiochemical Properties, and Nutritional Accessibility of Millets -- Chapter 11. Emerging Technologies in Millet Processing -- Chapter 12. Millet Food Products -- Chapter 13. Byproducts from Millet Processing Industry -- Chapter 14. Quality Standards for Millets -- Chapter 15. Millet Industry Scenario -- Chapter 16. Toxins in Millets.-.
    Abstract: The book offers an updated perspective on the unique characteristics of millets. Millets are consumed for their health/nutritional benefits, and in the preparation of specialty foods for target groups – from pediatrics to geriatrics. Recent trends suggest the importance of millet in the human diet due to their nutritional importance, ability to grow in high temperatures and drought conditions, and their resistance to pests and diseases. This book highlights different types of millet and discusses their properties as well as nutritional and anti-nutritional values. In addition, the book also provides information on the physiochemical properties, future prospects, current methodologies, and agricultural practices. The last few parts cover the emerging technologies in millet processing, by-products utilization, quality standards, and the current millet industry scenario. The book provides a comprehensive overview of the status of millet processing, quality, and nutraceutical product manufacture. The book is a resourceful read for students and researchers in food sciences, as well as industry experts.
    Type of Medium: Online Resource
    Pages: VII, 386 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811672248
    DDC: 610.72
    Language: English
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  • 63
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Human physiology. ; Physiology. ; Internal medicine. ; Medicine Research. ; Biology Research. ; Human Physiology. ; Physiology. ; Internal Medicine. ; Biomedical Research.
    Description / Table of Contents: Architecture of the vessel wall -- Ultrastructure of vascular smooth muscle -- Vascular endothelium -- Electrical and mechanical properties of vascular smooth muscle -- Biochemistry of the contractile proteins of smooth muscle -- Metabolism of vascular smooth muscle -- Neurotransmitters -- Endothelium-derived factors -- Local metabolic factors -- Shear stress, myogenic response, and blood flow autoregulation -- Intracellular Ca2+ regulation -- Regulation of myosin light chain phosphorylation -- Cyclic AMP signaling -- Cyclic GMP signaling -- MicroRNAs and vasoreactivity -- Extracellular vesicles as unique signaling messengers -- Genetic and epigenetic modification -- Coronary vasoreactivity -- Cerebral vasoreactivity -- Pulmonary vasoreactivity -- Renal vasoreactivity -- Hypoxic vasoreactivity -- Ageing and vasoreactivity.
    Abstract: This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on newly identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The second edition intends to update the contents of the first edition with the latest achievements in the regulation of vascular activities from biochemical, structural, genetic, physiological, and pharmacological aspects. In addition, two new chapters related to microRNA and extracellular vesicles have been added to reflect their newly discovered important roles in vascular activities. The contraction and dilatation activities of vasculature are of fundamental importance for maintaining circulation homeostasis and adapting to physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology.
    Type of Medium: Online Resource
    Pages: XV, 424 p. 1 illus. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9789811971228
    DDC: 612
    Language: English
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  • 64
    Keywords: Immunology. ; Diseases Causes and theories of causation. ; Autoimmunity. ; Medicine Research. ; Biology Research. ; Immunology. ; Pathogenesis. ; Autoimmunity. ; Biomedical Research.
    Description / Table of Contents: PART I: HUMAN MICROBIOME, VACCINES AND AUTOIMMUNITY -- Chapter 1. Autoimmunity and Microbiome -- Chapter 2. The vaccines induced autoimmunity -- Chapter 3. COVID-19 and Autoimmunity -- Chapter 4. The protective discourse between infections and autoimmunity -- PART II: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE KIDNEY DISEASES & ADRENAL INSUFFICIENCY -- Chapter 5. Microorganisms in pathogenesis and management of Anti-Neutrophil Cytoplasmic Antibody- (ANCA)- Associated Vasculitis -- Chapter 6. Microorganisms in pathogenesis and management of IgA Vasculitis and IgA Nephropathy -- Chapter 7. Microorganisms in pathogenesis and management of immune mediated glomerulopathies -- Chapter 8. Microorganisms in pathogenesis and management of Autoimmune Addison’s Disease (ADD) -- PART III: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF CENTRAL NERVOUS SYSTEM (CNS) DEMYELINATING AUTOIMMUNE DISEASES -- Chapter 9. Microorganisms in pathogenesis and management of Multiple Sclerosis (MS) -- Chapter 10. Microorganisms in pathogenesis and management of Guillain-Barre syndrome (GBS) -- Chapter 11. Microorganisms in pathogenesis and management of Neuromyelitis Optica -- Chapter 12. Microorganisms in pathogenesis and management of Acute Disseminated Encephalomyelitis (ADEM) -- PART IV: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF INFLAMMATORY BOWEL DISEASES (IBDs) -- Chapter 13. Microorganisms in pathogenesis and management of Ulcerative colitis (UC) -- Chapter 14. Microorganisms in pathogenesis and management of Crohn’s disease (CD) -- Chapter 15. Microorganisms in pathogenesis and management of Pouchitis -- Chapter 16. Microorganisms in pathogenesis and management of Coeliac Disease -- PART V: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE BLOOD & BLOOD VESSEL DISORDERS -- Chapter 17. Microorganisms in pathogenesis and management of Anti-Phospholipid Syndrome (Hughes syndrome) -- Chapter 18. Microorganisms in pathogenesis and management of Behçet Disease (BD) -- Chapter 19. Microorganisms in pathogenesis and management of Immune Thrombocytopenia -- PART VI: MICROORGANISMS IN PATHOGENESIS & MANAGEMENT OF AUTOIMMUNE EYE DISEASES -- Chapter 20. Microorganisms in pathogenesis and management of Autoimmune Uveitis -- Chapter 21. Microorganisms in pathogenesis and management of Autoimmune Retinopathy (AIR) -- Chapter 22. Microorganisms in pathogenesis and management of Type 1 Diabetes (T1D) -- Chapter 23. The influence of the microbiome and genetic associations on immune functions and on autoimmune and autoinflammatory diseases -- Chapter 24. Current challenges in research with exploring the microbial pathomechanisms of Autoimmune diseases -- Chapter 25. Future therapeutic prospects in dealing with autoimmune diseases: Treatment Based on the Microbiome Model.
    Abstract: This book, which is the second volume of Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases, provides comprehensive coverage on how microbial pathogens can subvert our immune system into responding against self and resulting in autoimmune diseases. In particular, the book covers the different aspects of linking gut microbiota dysbiosis with autoimmune mechanisms involved in disease development to identify future effective approaches based on the gut microbiota for preventing these autoimmune diseases. Contributions in the book focus on the role of microbiota/probiotics and their distinct mechanisms exerted in the management of autoimmune diseases of the kidney, central nervous system, eye, blood vessel, and bowel. This could help in better understanding to design of therapeutic strategies that can be deployed to prevent these autoimmune diseases. The book has an interdisciplinary appeal and scholars with an interest in immunology, medical microbiology, and nutritional sciences will value its contribution. Overall, the book gives new dimension and insight into the aspects of microbial role in autoimmune disease pathogenesis.
    Type of Medium: Online Resource
    Pages: XXI, 542 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811948008
    DDC: 571.96
    Language: English
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  • 65
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Plant molecular biology. ; Plant cells and tissues. ; Botanical chemistry. ; Plant Physiology. ; Plant Molecular Biology. ; Plant Cell Biology. ; Plant Biochemistry.
    Description / Table of Contents: Chapter 1. Metabolic Engineering: New approaches in Pharmaceuticals Production -- Chapter 2. Ameliorating abiotic stress tolerance in crop plants by metabolic engineering -- Chapter 3. Enhancing Photosynthetic Efficiency of Crop Through Metabolic Engineering -- Chapter 4. Transcription factor mediated plant metabolite production in response to environmental stress factors: current understanding and future aspects -- Chapter 5. Secondary Metabolite Engineering for Plant Immunity against Various Pathogens -- Chapter 6. Role of metabolic engineering in enhancing crop nutritional quality -- Chapter 7. miRNA and RNAi Mediated Metabolic Engineering in Plants -- Chapter 8. CRISPR/Cas genome editing in engineering plant secondary metabolites of therapeutic benefits -- Chapter 9. Enhanced Production of plant aromatic compounds through metabolic engineering -- Chapter 10. Molecular Farming: Sustainable manufacturing of vaccines, antibodies and other therapeutic substances -- Chapter 11. CRISPR/Cas Mediated Genome Engineering for Abiotic Stress Resilience in Plants -- Chapter 12. CRISPR/Cas Mediated Genome Engineering for Abiotic Stress Resilience in Plants -- Chapter 13. Use of Metabolic Engineering/Biotechnology in Crops Breeding and Development of New Crops -- Chapter 14. Improving the quality of medicinal and aromatic plants through metabolic engineering -- Chapter 15. Polymeric composites: A promising tool for enhancing photosynthetic efficiency of crops -- Chapter 16. Metabolic engineering approaches to produce compounds of interest in plants -- Chapter 17. Carbon-based Nanomaterials: An efficient tool for improving the nutritional quality of crops -- Chapter 18. Plant Metabolic Engineering for a Futuristic Economy -- Chapter 19. Ethical perspectives and limitations of metabolic engineering technologies in plants.
    Abstract: This edited book highlights the plant and cell/organ culture systems, and environmental and genetic transformation-based modulation of biochemical pathways. Special focus is given to microRNA-based technology, heterologous systems expression of enzymes and pathways leading to products of interest, as well as applications using both model and non-model plant species. Metabolic engineering is usually defined as the re-routing of one or more enzymatic reactions to generate new compounds, increase the production of existing compounds, or facilitate the degradation of compounds. Plants are the foundation of numerous compounds which are synthesized via assimilated complex biosynthetic routes. Plants have evolved an incredible arrangement of metabolic pathways leading to molecules/compounds capable of responding promptly and effectively to stress situations imposed by biotic and abiotic factors, some of which supply the ever-growing needs of humankind for natural chemicals, such as pharmaceuticals, nutraceuticals, agrochemicals, food and chemical additives, biofuels, and biomass. However, in foreseeable future we will be forced to think about the accessibility of resources for the generations to come. For these reasons, the book proposes alternative options of food/food supplement, medicines and other essential items, by using plant metabolic engineering approach. This book is of interest to teachers, researchers and academic experts. Also, the book serves as additional reading material for undergraduate and graduate students of biotechnology and molecular biology of plants.
    Type of Medium: Online Resource
    Pages: XII, 413 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811672620
    DDC: 571.2
    Language: English
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    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    DDC: 615
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Diagnosis. ; Molecular biology. ; Cancer. ; Biomedical Research. ; Clinical Genetics. ; Diagnosis. ; Molecular Biology. ; Cancer Biology.
    Description / Table of Contents: Chapter 1. Age-Rage Stress In The Pathophysiology Of Atherosclerosis And Its Treatment -- Chapter 2. Stem Cells In Dermatology: What The Future May Hold -- Chapter 3. Current Advances And Future Avenues In Endocrinology -- Chapter 4. Autologous Conditioned Serum In Lumbar And Cervical Radiculopathy: A Systematic Review -- Chapter 5. Bench To Bedside In Ophthalmology -- Chapter 6. Rapid Eye Movement In Sleep And Dream Sleep -- Chapter 7. Novel Cellular-Stress Models With Implications In Understanding And Treating Ent Pathologies -- Chapter 8. Respiratory Disorders : Contemporary Issues In 2020 -- Chapter 9. Discovery Of Hepatitis Viruses And Two Nobel Prizes : A Tale Of Observations Serendipity Collaboration Research Institute Inter Predated And Game Changing Innovation. Chapter 10. Conventional And Modern Approaches For Clinical And Laboratory Diagnosis Of Tuberculosis -- Chapter 11. Gut Microbes In Cardiovascular Diseases -- Chapter 12. Heart Failure – Future Perspectives -- Chapter 13. IL-10 : A Key Molecular In The Mitigation Of Heart Failure -- Chapter 14. Gene Therapy In Liver Disease : Challenges And Outcomes -- Chapter 15. Interrupting Crystal To Calculus Conversion : The Future Of Research In Urolithiasis -- Chapter 16. Stem Cells – Medical Marvel In Management Of Kidney Diseases -- Chapter 17. Deciphering The Code Of Male Infertility : Genetic Tests, Counselling And Molecular Basis Of Spermatogenic Failure -- Chapter 18. Translational Epidemiology In Cancer Research : The Less Travelled Path -- Chapter 19. Adenosine Pathway In Genitourinary Malignancies: A Promising Immunotherapeutic Target -- Chapter 20. Immune Checkpoint Inhibitors In Cancer Therapy: A Ray Of Hope -- Chapter 21. Recent Developments In The Immunotherapeutic Approaches For Cancer Treatment. Chapter 22. Thrombotic Complications In Women : Risks And Prevention -- Chapter 23. Biomedical Science And Women Health -- Chapter 24. Advances In The Role Of Macronutrients In Human Health And Diseases.
    Abstract: The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.
    Type of Medium: Online Resource
    Pages: XIV, 491 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811688454
    DDC: 610.72
    Language: English
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  • 68
    Keywords: Plant biotechnology. ; Plants Development. ; Plant physiology. ; Botanical chemistry. ; Plant Biotechnology. ; Plant Development. ; Plant Physiology. ; Plant Biochemistry.
    Description / Table of Contents: Chapter 1. Improved sterilization techniques for successful in vitro micropropagation -- Chapter 2. Selection and preparation of explants for the clonal propagation of horticultural plants in plant factory systems -- Chapter 3. Use of alternative components in cost-effective media for mass production of clonal plants -- Chapter 4. Novel plant growth regulators in in vitro establishment of horticulture and plantation crops -- Chapter 5. Potential role and utilization of Piriformospora indica: fungal endophytes in commercial plant tissue culture -- Chapter 6. Application of biostimulants in establishing and acclimatizing in vitro-raised plants -- Chapter 7. Nanomaterials and plant tissue culture: Developmental path and contradictory facts -- Chapter 8. Somatic embryogenesis in cashew (Anacardium occidentale L.) -- Chapter 9. Somatic embryogenesis and plant regeneration in horticultural crops -- Chapter 10. Prospect and commercial production of economically important plant mulberry (Morus sp.) towards the upliftment of rural economy -- Chapter 11. Assessing the genetic stability of in vitro raised plants -- Chapter 12. Improvement of plant survival and expediting acclimatization process -- Chapter 13. Evaluation of genetic stability of in vitro raised orchids using molecular based markers -- Chapter 14. Recent in-vitro propagation advances in Genus Paphiopedilum – Lady Slipper Orchids.
    Abstract: This edited book is focusing on the novel and innovative procedures in tissue culture for large scale production of plantation and horticulture crops. It is bringing out a comprehensive collection of information on commercial scale tissue culture with the objective of producing high quality, disease-free and uniform planting material. Developing low cost commercial tissue culture can be one of the best possible way to attain the goal of sustainable agriculture. Tissue culture provides a means for rapid clonal propagation of desired cultivars, and a mechanism for somatic hybridization and in vitro selection of novel genotypes. Application of plant tissue culture technology in horticulture and plantation crops provides an efficient method to improve the quality and nutrition of the crops. This book includes a description of highly efficient, low cost in vitro regeneration protocols of important plantation and horticulture crops with a detailed guideline to establish a commercial plant tissue culture facility including certification, packaging and transportation of plantlets. The book discusses somatic embryogenesis, virus elimination, genetic transformation, protoplast fusion, haploid production, coculture of endophytic fungi, effects of light and ionizing radiation as well as the application of bioreactors. This book is useful for a wide range of readers such as, academicians, students, research scientists, horticulturists, agriculturists, industrial entrepreneurs, and agro-industry employees.
    Type of Medium: Online Resource
    Pages: IX, 335 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811900556
    DDC: 631.52
    Language: English
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  • 69
    Keywords: Microbiology. ; Plant physiology. ; Botanical chemistry. ; Plant anatomy. ; Microbiology. ; Plant Physiology. ; Plant Biochemistry. ; Plant Anatomy and Morphology.
    Description / Table of Contents: 1 Endophytic Bacteria: Application against biotic and abiotic stresses and Plant Health Improvements for Sustainable Agriculture -- 2 Endophytic Bacteria: Mitigating Abiotic Stress from Inside -- 3 Diversity and bioactive potential of endophytic bacteria from high-value medicinal plants -- 4 Plant Growth Promoting Rhizobacteria (PGPR) Assisted Phytoremediation of Contaminated Soils -- 5 Endophytic Bacteria: Role in Phosphorous Solubilization -- 6 Endophytes of Medicinal plants: Diversity and Bioactivity -- 7 Title: Biotechnological applications of Bacterial Endophytes -- 8 Genetic Basis of Fungal Endophytic Bioactive Compounds Synthesis, Modulation, and Their Biotechnological Application -- 9 Endophytic bacteria for plant growth promotion -- 10 Bacterial Endophytes and Bio-nanotechnology -- 11 Role of Endophyte Metabolites in Plant Protection and other Metabolic Activities -- 12 Role of Bacterial Endophytes in the Promotion of Plant Growth -- 13 Bacterial endophytes and abiotic stress mitigation. .
    Abstract: This book is a comprehensive account of recent advances in the endophytic research. It covers recent perspective of endophytic research, molecular diversity, bioprospecting of novel genes using high throughput molecular techniques, and most importantly application of endophytes in practicing sustainable agriculture. Endophytic micro-organisms are mysterious living component associated mutually with plant roots and soil microbes. Various endophytic bacteria have attracted considerable attention for their ability to promote plant growth through direct mechanisms or by acting as biocontrol agents. Endophytes also find use in biocontrol, medicine, agriculture and food industry. This is a useful reading for the student of agriculture, environmental microbiology and biotechnology.
    Type of Medium: Online Resource
    Pages: VIII, 278 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811644979
    DDC: 579
    Language: English
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  • 70
    Keywords: Medicine Research. ; Biology Research. ; Nanobiotechnology. ; Biotechnology. ; Nanomedicine. ; Biomedical Research. ; Nanobiotechnology. ; Biotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1_Biosensing: Material, methods and principle of detection -- Chapter 2_Biosensing applications in the development of medical devices -- Chapter 3_Theranostics: basic principles -- Chapter 4_Material and technique advancements in the development of theranostic products -- Chapter 5_Medical device development strategies -- Chapter 6_Research aspects for the development of medical devices -- Chapter 7_Biosensor-based commercialized point-of-care devices -- Chapter 8_Medical devices in clinical set up -- Chapter 9_Clinical validation of medical devices -- Chapter 10_Regulatory steps involved in the validation of medical devices -- Chapter 11_Protocol for registration process of point-of-care device at FDA or equivalent agencies -- Chapter 12_Opportunities and challenges in medical device development -- Chapter 13_Prospective journey of the research idea from laboratory to the user in the clinic. .
    Abstract: This book provides up-to-date information on the prototypes used to develop medical devices and explains the principles of biosensing and theranostics. It also discusses the development of biosensor and application-orientated design of medical devices. In addition to summarizing the clinical validation of the developed techniques and devices and the regulatory steps involved in their commercialization, the book highlights the latest research and translational technologies toward the development of point-of-care devices in the health care. Lastly, it explores the current opportunities, challenges and provides troubleshooting on the use of biosensors in precision medicine. The book is helpful for researchers and medical professionals working in the field of clinical theranostics, and medical-device development wanting to gain a better understanding into the principles and processes involved in the development of biosensors.
    Type of Medium: Online Resource
    Pages: IX, 376 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811627828
    DDC: 610.72
    Language: English
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  • 71
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Sports sciences. ; Medical informatics. ; Biomedical Research. ; Bioinformatics. ; Sport Science. ; Health Informatics.
    Description / Table of Contents: Chapter 1. Ontologies and Knowledge Graphs for Exercise Medicine -- Chapter 2. Participatory exercise medicine and personalized healthcare -- Chapter 3. Integration of genetic and phenotyping data for sports medicine -- Chapter 4. Microbiota, sports and exercise medicine -- Chapter 5. Human immune system and exercise medicine: current process and future directions -- Chapter 6. Circadian Rhythm and Personalized Exercise -- Chapter 7. Data-driven Exercise Medicine for Cardiovascular Disease -- Chapter 8. Physical Activities and Prevention of Neurodegenerative Diseases -- Chapter 9. Exercise guidelines for cancer patients -- Chapter 10. Diabetes as a metabolic disease and translational exercise medicine informatics.
    Abstract: The book provides readers the informatics and data-driven models for the discovery of personalized excise prescriptions applied to different cases. Overdiagnosis or over-treatment often happened since the complex interaction among the lifestyle, genetic, and environmental factors. Sports and exercise are reported efficient to prevent or reduce the risk of diseases, but the interactions between sports/exercise and disease are personalized and complex. Translational informatics is a powerful paradigm and it promotes the transfer of big data, knowledge and models to the precision application of sports to prevent diseases. Sports and exercise may have different effects on diverse diseases including cancers, neurodegenerative disease, and cardiovascular diseases, etc. This book covers many modern informatics models such as ontologies, knowledge graphs, blockchain, participatory medicine, semantic artificial intelligence, big data modeling, and so on. It also describes the challenges for the sports and exercise medical data sharing and standardization, the privacy protection of data as well as the integration of data from genomic level to physiological phenotype level. This book will be helpful to the readers who are interesting in sports and exercise medicine, healthcare, big data modeling, artificial intelligence in medicine and healthcare. .
    Type of Medium: Online Resource
    Pages: IX, 234 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811691621
    DDC: 610.72
    Language: English
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  • 72
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Stress (Physiology). ; Plants. ; Botanical chemistry. ; Plant molecular biology. ; Plant Physiology. ; Plant Stress Responses. ; Plant Biochemistry. ; Plant Molecular Biology.
    Description / Table of Contents: Chapter 1. Role of Potassium in Plant Photosynthesis, Transport, Growth and Yield -- Chapter 2. Potassium Role in Plants Response to Abiotic Stresses. Chapter 3. Molecular Approaches to Potassium Uptake and Cellular Homeostasis in Plants under Abiotic Stress -- Chapter 4. Soil Potassium Availability and Role of Microorganisms in Influencing Potassium Availability to Plants -- Chapter 5. Crosstalk of Potassium and Phytohormones under Abiotic Stress -- Chapter 6. Potassium (K+) Regulation by Phytohormones under Abiotic Stress -- Chapter 7. Role of Potassium in Drought Adaptation: Insights into Physiological and Biochemical Characteristics of Plants -- Chapter 8. Role of Potassium in Heavy Metal Stress -- Chapter 9. Salt Stress Alleviation Strategies to Maintain K+ Homeostasis in Plants -- Chapter 10. Potassium ion Homeostasis, Signaling and Changes in Transcriptomes and Metabolomes Enduring Salinity Stress -- Chapter 11. Potassium: A Potent Modulator of Plant Responses under Changing Environment -- Chapter 12. An Overview of Potassium in Abiotic Stress: Emphasis on Potassium Transporters and Molecular Mechanism -- Chapter 13. Nitric Oxide Synthesis Affects Potassium and Nitrogen Homeostasis in Plants for Salt Tolerance.
    Abstract: This book on potassium in abiotic stress tolerance deals with the ongoing trend in increasing abiotic stresses and interlinked issues food security. As mineral nutrient potassium holds an important place in agriculture and is involved in various physiological and biochemical processes. It takes part in protein synthesis, carbohydrate metabolism, enzyme activation, cation-anion balance, osmoregulation, water movement, energy transfer, and regulates stomata and photosynthesis. Potassium plays an important role as abiotic stress buster. This book will deal with potassium relevance to plant functions and adaptations, range of its biological functions, role of potassium in abiotic stress tolerance, analyses of mechanisms responsible for perception and signal transduction of potassium under abiotic stress, critical evaluation of and cross-talks on nutrients and phytohormones signaling pathways under optimal and stressful conditions, and interaction of potassium with other nutrients for abiotic stress tolerance. This book will be of interest to teachers, researchers, scientists working on abiotic stresses. Also, the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, and environmental sciences. National and international agricultural scientists, policymakers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XV, 281 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811644610
    DDC: 571.2
    Language: English
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  • 73
    Keywords: Agriculture. ; Agronomy. ; Agricultural biotechnology. ; Plants. ; Stress (Physiology). ; Plant physiology. ; Agriculture. ; Agronomy. ; Agricultural Biotechnology. ; Plant Signalling. ; Plant Stress Responses. ; Plant Physiology.
    Description / Table of Contents: Part 1 Introduction -- 1 World Rice Production: An Overview -- 2 Climate Change and Global Rice Security -- Part 2 Agronomic Management -- 3 Techniques of Rice Nursery Establishment and Transplanting -- 4 Rice Seed and Seedling Priming -- 5 Nursery Management of Transplanted Rice -- 6 Rice Cultivation Systems -- 7 Smart Nutrient Management in Rice Crop -- 8 Irrigation Management in Rice -- 9 Rice-Based Cropping Systems -- 10 Rice Ontogeny -- 11 Rice Phenotyping -- 12 Rice Physiology under Changing Climate -- 13 Water-Wise Cultivation of Basmati Rice in Pakistan -- 14 Rice Interactions with Plant Growth Promoting Rhizobacteria -- 15 Plant Growth Regulators for Rice Production in Changing Environment -- 16 Salinity Tolerance in Rice -- 17 Rice Pollination -- Part 3 Plant Protection -- 18 Plant Protection Strategies in Rice Crop -- 19 Weed Management Strategies in Direct Seeded Rice -- 20 Contemporary Management of Insect Pests in Rice -- 21 Insect Chitin Biosynthesis and Regulation Using RNAi Technology -- 22 Integrated Management of Rice Diseases -- 23 Diversity and Management of Plant Viruses Infecting Rice -- 24 Botanical Extracts for Rice Fungal Diseases -- 25 Nanotechnology for Rice Fungal Diseases -- 26 Rice Nematodes and their Integrated Management -- Part 4 Advanced Technologies -- 27 Managing Greenhouse Gas Emission -- 28 Applications of Crop Modeling in Rice Production -- 29 Climate Change and Rice Production: Impacts and Adaptations -- 30 Rice Production and Crop Improvement Through Breeding and Biotechnology -- 31 Hybrid Rice Production -- 32 Rice Biotechnology -- 33 New Breeding Techniques (NBTs) for Improving Rice Grain Yield to Feed 10 Billion: Progress and Prospects -- 34 CRISPR/Cas9 for Rice Crop Improvement: Recent Progress, Limitations and Prospects -- Part 5 Nutritional Aspects -- 35 Rice Nutritional Aspects -- 36 Rice Grain Quality -- 37 Phytochemical Composition of Rice -- 38 Rice Based Products -- Part 6 Miscellaneous -- 39 Advances Approached to Mitigate Abiotic Stresses in Rice (Oryza sative L.) Crop -- 40 Is Geographical Indication System an Opportunity for Developping-8 (D-8) Countries? An Evaluation of Registered Rice Production.
    Abstract: This book collects all the latest technologies with their implications on the global rice cultivation. It discusses all aspects of rice production and puts together the latest trends and best practices in the rice production. Rice is produced and consumed worldwide and especially an important crop for Asia. It is a staple food in majority of population living is this continent which distinguishes this from rest of the world. Climatic fluctuations, elevated concentrations of carbon dioxide, enhanced temperature have created extreme weather conditions for rice cultivation. Also, increasing pest attacks make situation complicated for the farmers. Therefore, rice production technology also has to be adjusted accordingly. This book is of interest to teachers, researchers, plant biotechnologists, pathologists, agronomists, soil scientists, food technologists from different part of the globe. Also, the book serves as additional reading material for students of agriculture, soil science, and environmental sciences. National and international agricultural scientists, policy makers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XVI, 866 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649554
    DDC: 630
    Language: English
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  • 74
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    DDC: 615
    Language: English
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  • 75
    Keywords: Agriculture. ; Stress (Physiology). ; Plants. ; Plant physiology. ; Agriculture. ; Plant Stress Responses. ; Plant Physiology.
    Description / Table of Contents: See attached. Chapter 1. Nanoremediation: An innovative approach for environmental safety -- Chapter 2. Sustainable agriculture and plant production by virtue of biochar in the era of climate change -- Chapter 3. Soil management vis-à-vis carbon sequestration in relation to land use cover/change in terrestrial ecosystem-a review -- Chapter 4. Salt-induced toxicity and anti-oxidantal response in Oryza sativa: An updated review -- Chapter 5. Soybean plants under waterlogging stress: Responses and adaptation mechanisms -- Chapter 6. Niger (Guizotia abyssinica (L. f.) Cass.) an oilseed crop under biotic stress -- Chapter 7. Role of phytohormones in antioxidant metabolism in plants under salinity and water stress -- Chapter 8. Plant phenolic compounds for abiotic stress tolerance -- Chapter 9. Efficacy of various amendments for the phyto-management of heavy metal contaminated sites and sustainable agriculture. A review -- Chapter 10. Exploring Plant Responses to Salinity and Implications of Halophytes as a Model for Salinity Improvement -- Chapter 11. Efficacy of Spinach (Spinacia oleracea) for the phyto-management of different heavy metals contaminated sites under chelating agent amendments. A review -- Chapter 12. Insights into Potential Roles of Plants as Natural Radioprotectants and Amelioration of Radiations Induced Harmful Impacts on Human Health -- Chapter 13. Development of rangeland conservation and sustainable management practices under changing climate -- Chapter 14. Biological Nitrogen Fixation: An Analysis of Intoxicating Tribulations from Pesticides for Sustainable Legume Production -- Chapter 15. Sustainable urban forestry, merits, demerits and mitigation of climate change at global scale -- Chapter 16. Temperate Forage Legumes Production, Weeds Dynamics and Soil C: N Economy under Organic Wastes -- Chapter 17. Atmospheric chemistry of aerosols and their role in global climate change -- Chapter 18. Increase in food scarcity, agriculture challenges and their management: Pakistan Perspectives. Chapter 19. Increase ability of transgenic plant expressing the bacterial enzyme to accumulate heavy metals.
    Abstract: This comprehensive edited volume collects the most recent information with up-to-date citations, on the decrease in plant productivity under climatic changes and its link with global food security. The book emphasis on the crop management practices and recent advancement in the techniques for mitigating the negative effects of climate induced biotic and abiotic stress. It brings together 19 chapters developed by eminent researchers in the area of plant and environmental sciences. Global climate change is increasingly becoming a concern for future of agriculture. High levels of inorganic and organic pollutants and climatic stress adversely affects the sensitive and complex equation of natural resources and ecosystem services. To meet the increased food demand, plant productivity needs to be enhanced, therefore this book fills in the gap and brings together information on the physiological and molecular approaches for improving crop productivity. The book is resourceful reading material for researchers, faculty members, graduate and post graduate students of plant science, agriculture, agronomy, soil science, botany, Molecular biology and environmental science.
    Type of Medium: Online Resource
    Pages: XXI, 477 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811650598
    DDC: 630
    Language: English
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  • 76
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Proteins. ; Biomaterials. ; Nanomedicine. ; Biomedical engineering. ; Biomedical Research. ; Biomaterials-Proteins. ; Nanomedicine and Nanotoxicology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Part 1 -- 1 Interactions between the physiological environment and titanium-based implant materials – from understanding to control -- 2 Nanoscale surface Engineering and Characterization of Biomaterial -- 3 Progress of Nanotechnology-based Detection and Treatment of Alzheimer’s Disease Biomarkers -- 4 Biomaterials: Types and Applications -- Part 2 -- 5 Additive Manufacturing of Ti and its alloy-based Bioimplants for Orthopaedic Applications -- 6 Physico-chemical Modifications of Magnesium and Alloys for Biomedical Applications -- 7 Metallic Foams in Bone Tissue Engineering -- 8 Surface modification of metallic biomaterials for cardiovascular cells regulation and biocompatibility improvement -- 9 Advancement of spinel ferrites for biomedical application -- Part 3 -- 10 Functionalized 3D bioactive polymeric materials in tissue engineering and regenerative medicine -- 11 Polymer matrixes used in wound healing applications. 12 Conductive Polymers for Cardiovascular Applications -- 13 Engineered polymeric materials/nanomaterials for growth factor/drug delivery in bone tissue engineering applications -- 14 Surface engineering of polymeric materials for bone tissue engineering -- 15 Antibacterial Surface Modification to Prevent Biofilm Formation on Polymeric Biomaterials -- 16 Polymer Surface Engineering in the Food Packaging Industry -- 17 Polymeric Membranes in Waste-water Treatment -- 18 Functionalized Fluoropolymer Membrane for Fuel Cell Applications -- Part 4 -- 19 Bioceramics for Biomedical Applications -- 20 Applications of nanomaterials in the textile industry -- 21 Properties and characterization of advanced composite materials -- 22 Properties and characterization of advanced composite materials -- 23 Nano composites application in sewage treatment and degradation of persistent pesticides used in agriculture -- 24 Biomimetic Mineralization of Electrospun PCL based Composite Nanofibrous Scaffold for hard tissue Engineering. .
    Abstract: This book provides a comprehensive overview of the latest advances in a wide range of biomaterials for the development of smart and advanced functional materials. It discusses the fundamentals of bio-interfacial interactions and the surface engineering of emerging biomaterials like metals and alloys, polymers, ceramics, and composites/nanocomposites. In turn, the book addresses the latest techniques and approaches to engineering material surfaces/interfaces in, e.g., implants, tissue engineering, drug delivery, antifouling, and dentistry. Lastly, it summarizes various challenges in the design and development of novel biomaterials. Given its scope, it offers a valuable source of information for students, academics, physicians and particularly researchers from diverse disciplines such as material science and engineering, polymer engineering, biotechnology, bioengineering, chemistry, chemical engineering, nanotechnology, and biomedical engineering for various commercial and scientific applications.
    Type of Medium: Online Resource
    Pages: X, 704 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811636677
    DDC: 610.72
    Language: English
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  • 77
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant diseases. ; Agricultural biotechnology. ; Plant physiology. ; Plant Pathology. ; Agricultural Biotechnology. ; Plant Physiology.
    Description / Table of Contents: 1. Phytopathometry: A trans-disciplinary concept -- 2. Visual Estimation: a classical approach for plant disease estimation -- 3. Remote Sensing: A new tool for disease assessment in crops -- 4. Image analysis and processing approach: an automated plant disease recognition technology -- 5. Hyper-spectral imaging through Spatial and Spectral Sensors for Phytopathometry -- 6. Fluorescent imaging system-based plant phenotyping for disease recognition -- 7. Concept and Application of Infrared Thermography for Plant Disease Measurement -- 8. Application of Biosensors in Plant Disease Detection -- 9. Immunotechnology for Plant Disease Detection -- 10. Molecular Phytopathometry -- 11. Microarray technology for detection of plant diseases -- 12. Predictive Models for Plant Disease Assessment -- 13. Extension Plant Pathology.
    Abstract: This edited book provides the readers with the concepts and in-depth knowledge of plant disease assessment and conventional and modern technologies that aid in precise and accurate phytomathometery. This book discusses the evolution of plant disease assessment procedures from the primary visual estimation-based assessment to modern approaches, their practical application for reliable disease quantification, yield loss estimation, and the efficacy of disease control strategies for sustainable crop protection. Significant information is provided on the major aspects of the topic, including remote sensing, imaging techniques, molecular phytopathometery, microarray, and immunotechnology. The book helps plant scientists, plant pathologists, practitioners, researchers, and students in disease quantification, developing predictive models for plant disease epidemics, assessing crop losses, and the magnitude of plant disease control methods. This book describes the classical plant disease assessment methods based on visual observations. It Provides information regarding the modern and emerging technologies in Phytopathometery, precision, and accuracy. This book also discusses the application of disease assessments in predictive models, disease warning systems, expert systems, and decision support systems in applied plant pathology.
    Type of Medium: Online Resource
    Pages: IX, 282 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811958960
    DDC: 571.92
    Language: English
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  • 78
    Keywords: Agronomy. ; Plant physiology. ; Stress (Physiology). ; Plants. ; Soil science. ; Agronomy. ; Plant Physiology. ; Plant Stress Responses. ; Soil Science.
    Description / Table of Contents: 1 Growth and development of sugarcane (Saccharum spp. hybrid) and its relationship with environmental factors -- 2 Impact of climate change on sucrose synthesis in sugarcane varieties -- 3 Impact of salinity stress on sugarcane yield and quality: management approaches for higher cane sugar productivity -- 4 Potential parents for developing climate-resilient sugarcane varieties in India- A breeding perspective -- 5 Bioactive silicon: approach to enhance sugarcane yield under stress environment -- 6 Anatomy of tolerance mechanisms in sugarcane crop to abiotic stresses -- 7 Interaction of plant growth-promoting rhizobacteria with sugarcane plants for alleviating abiotic stresses and improving crop yields -- 8 Morpho-physiological, biochemical and ultrastructural modifications on sugarcane to prolonged water deficit -- 9 Impact of heavy metal toxicity on sugarcane growth, development and productivity -- 10 Defense-related proteins in sugarcane and their role in disease resistance: molecular advancements and beyond -- 11 Impact of green and organic fertilizers on soil fertility and sugarcane productivity -- 12 Silicon-induced mitigation of low temperature stress in sugarcane -- 13 Agro-technologies to sustain sugarcane productivity under abiotic stresses -- 14 Biotechnological approaches to improve sugarcane quality and quantum under environmental stresses -- 15 Biotic stresses in sugarcane plants and its management -- 16 Weeds management in sugarcane: recent developments and future perspectives -- 17 Synergistic integration of sugarcane - proteogenomics to decipher the mechanism of disease resistance in sugarcane -- 18 The metabolic interaction of potassium salt of active phosphorus (PSAP) and its stimulatory effects on the growth and productivity of sugarcane under stressful environment.
    Abstract: This edited volume focuses on the core aspects of sugarcane production-management under stressful environments as well as innovative strategies for augmenting crop growth & productivity through intrinsic and extrinsic manipulations. The various chapters aim at bringing out comprehensive and advance information on different aspects of sugarcane cultivation under stress environments and impact of climate change on the sustainability of sugarcane production. The book encompasses information about crop production management, physiological & nutritional requirements, ratooning, ripening and post-harvest losses management. It also delineates various technologies that support the continued use and improvement of sugarcane as renewable source of food, fiber and bio-energy. The manipulations at cellular and molecular levels, molecular breeding approaches and post-harvest technologies are also included. The area under sugarcane cultivation is gradually increasing because of its diversification potential. The high productivity and biomass of the cane crop also makes it a key source for use as bio-energy crop and a promising raw material for bio-based agro-industries. However, poor crop & biomass productivity due to abiotic stress is the foremost constraint in its future commercial exploitation as sustainable feed-stock for bio-based industries. It is therefore imperative to understand the cellular-molecular modulation responsible to productivity barrier under specific stress situation(s) for better sugarcane quality and quantum under field condition. Some of these innovative approaches are delineated in this book. This book is of interest to progressive sugarcane growers, millers, industrial entrepreneurs, sugarcane scientists, cane development and extension officers, sugar industry managers and valuable source of reference worldwide.
    Type of Medium: Online Resource
    Pages: XIX, 426 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811939556
    DDC: 630
    Language: English
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  • 79
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Immunology. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Immune system. ; Cellular signal transduction. ; Immunotherapy. ; Immunology. ; Biotechnology. ; Biomedical Research. ; Immune Cell Signalling. ; Immunotherapy. ; Applied Immunology.
    Description / Table of Contents: Chapter 1. Classification, Mode of Action and Uses of Various Immunomodulators -- Chapter 2. Potential role of herbs and spices on the immune system -- Chapter 3. Immune booster activity of Prebiotics -- Chapter 4. Antioxidants and Immunomodulation -- Chapter 5. Nanotechnology and Immunomodulators in Cancer -- Chapter 6. Advancements in the field of Oral, Intravenous and Inhaled Immunomodulators using Nanotechnology -- Chapter 7. Phytochemicals as the source of Natural Immunomodulator & their role in Cancer Chemoprevention -- Chapter 8. Immunomodulators and Autoimmune Liver Diseases -- Chapter 9. Immunomodulatory role for the treatment and management of tuberculosis -- Chapter 10. Immunomodulation in Autoimmune Disorders -- Chapter 11. Psychology, Epigenetics, Immunomodulation and Immune Dysfunction: Understanding the Connection -- Chapter 12. Herbal Immunomodulators and COVID-19 -- Chapter 13. Role of Cytokines as Immunomodulators -- Chapter 14. Immunomodulatory properties of proteins and peptides: Food derivates approach -- Chapter 15. Fatty Acids and Immunomodulation -- Chapter 16. Immunomodulatory Effects of Endocrine Disrupting Chemicals.-.
    Abstract: This book focuses on a broad range of immunomodulators, including both natural and synthetic ones. It highlights their role in human health. The book discusses nanotechnology-based immunomodulators with special emphasis on different types of formulation to boost the immune system. It highlights the role of immunomodulators against different microbes. This book describes important topics such as Classification and uses of various immunomodulators; Potential role of herbs and spices on immune system; Immune booster activity of prebiotics; Recent advances of nutraceutical and functional foods in Immune health; Antioxidants and immunomodulation; Nanotechnology and immunomodulators in cancer; Immunomodulatory role for the treatment and management of tuberculosis; Immunomodulation in autoimmune disorders; Herbal immunomodulators and COVID-19; Role of Cytokines as Immunomodulators and Immunomodulatory effects of endocrine disrupting chemicals. This book covers various aspects of product innovation, development, and launching of nutritional and pharmaceutical products with reference to immunomodulators. This book is meant for researchers and students in the field of immunology and pharmaceutical sciences.
    Type of Medium: Online Resource
    Pages: XVIII, 509 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811663796
    DDC: 571.96
    Language: English
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  • 80
    Keywords: Agriculture. ; Genetics. ; Plant physiology. ; Stress (Physiology). ; Plants. ; Agriculture. ; Genetics and Genomics. ; Plant Physiology. ; Plant Stress Responses.
    Description / Table of Contents: Small Millets - the Next-Generation Smart Crops in the Modern Era of Climate Change -- Omics for abiotic stress tolerance in foxtail millet -- Current status and future prospects of omics strategies in barnyard millet -- Role of inducible promoters and transcription factors in conferring abiotic stress-tolerance in small millets -- Genome-wide identification and expression profiling of non-coding RNAs in response to abiotic stresses in small millets -- Insights into abiotic stress tolerance in small millets through transcriptomics -- Role of proteomics in understanding the abiotic stress tolerance in minor millets -- Plant regeneration and transgenic approaches for the development of abiotic stress tolerant small millets -- Mining genes and markers across minor millets using comparative genomics approaches -- Improving the nutrient-use efficiency in millets by genomics approaches -- Current status of bioinformatics resources of small millets -- Advances in omics for enhancing abiotic stress tolerance in finger millets -- Genome editing approaches for abiotic stress tolerance in small millets -- Integrating genomics and phenomics tools to dissect climate resilience traits in small millets -- Abiotic stress tolerant small millet plant growth regulation by long noncoding RNAs: an omics perspective -- Omics of climate change on nutritional quality of small millets -- Exploring genome wide analysis of heat shock proteins (HSPs) in small millets as potential candidates for development of multistress tolerant crop plants.
    Abstract: This edited book covers all aspects of omics approaches used for the varietal improvement of millets in changing climatic conditions. Millets are the collection of small-grained cereal grasses, that are grown for human carbohydrate needs. They are among the oldest crops, mainly divided into two groups – Major and small millets based on seed size. Small millets are earlier considered orphan crops, but recently due to their nutritional values, they are getting importance in cultivation. This book explores the genomics, transcriptomics, proteomics, metabolomics, bioinformatics, and other omics tools that are being widely used to get a clear understanding of mechanistic approaches taken by plant genes to tolerate stress. Various reports are published based on field breeding on these crops, and recently the genome of some of the small millets is released, and many omics studies are published related to its application in varietal improvements. This book reviewed all those recent studies and is of interest to research students, plant breeding scientists, teachers that are working in agriculture and plant biotech universities. Along with this, the book serves as reference material for undergraduate and graduate students of agriculture, and biotechnology. National and international agricultural scientists, policymakers will also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XIX, 355 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811939075
    DDC: 630
    Language: English
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  • 81
    Keywords: Biotechnology. ; Nanotechnology. ; Medicine Research. ; Biology Research. ; Industrial microbiology. ; Pharmaceutical chemistry. ; Biotechnology. ; Nanotechnology. ; Biomedical Research. ; Industrial Microbiology. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1.Impact of isotropic and anisotropic plasmonic metal nanoparticles on healthcare and food-safety management -- Chapter 2. An introduction to different methods of nanoparticles synthesis -- Chapter 3. Classification, Synthesis, and Application of Nanoparticles against Infectious Diseases -- Chapter 4. Nanotechnology in Food Science -- Chapter 5. Facets of Nanotechnology in food processing, packaging and safety: an emerald insight -- Chapter 6. Nanotechnology and its potential application in postharvest technology -- Chapter 7. Nanotechnology mediated detection and control of phytopathogens -- Chapter 8. Nanosystems for Cancer Therapy -- Chapter 9. Phytoplankton mediated nanoparticles for cancer therapy. Chapter 10. Nanotechnology and its potential implications in Ovary Cancer -- Chapter 11. Nanotechnology: An Emerging Field in Protein Aggregation and Cancer Therapeutics -- Chapter 12. Bio-nano interface and its potential application in Alzheimer’s disease -- Chapter 13. Potential of curcumin nanoparticles in tuberculosis management -- Chapter 14. Application of Nanobiosensor in Health care sector -- Chapter 15. Bioactive nanoparticles: A next generation smart nanomaterials for pollution abatement and ecological sustainability -- Chapter 16. Smart nano-materials for bio-imaging applications:An overview -- Chapter 17. Biology of Earthworm in a World of Nano-materials: New Room, Challenges and, Future Perspectives -- Chapter 18. Bioethanol production from agricultural wastes with the aid of nanotechnology -- Chapter 19. Nanotechnology for sustainable bioenergy production.
    Abstract: This book discusses the unique interactions of nanoparticles with various biomolecules under different environmental conditions. It describes the consequences of these interactions on other biological aspects like flora and fauna of the niche, cell proliferation, etc. The book provides information about the novel and eco-friendly nanoparticle synthesis methods, such as continuous synthesis of nanoparticles using microbial cells. Additionally, the book discusses nanoparticles' potential impact in different areas of biological sciences like food, medicine, agriculture, and the environment. Due to their advanced physicochemical properties, nanoparticles have revolutionized biomedical and pharmaceutical sciences. Inside the biological milieu, nanoparticles interact with different moieties to adopt stable shape, size, and surface functionalities and form nano-biomolecular complexes. The interaction pattern at the interface form complexes determines the fate of interacting biomolecules and nanoparticles inside the biological system. Understanding the interaction pattern at the nano-bio interface is crucial for the safe use of nanoparticles in natural sciences. This book rightly addresses all questions about the interaction and the ensuing structure and function of these nano-biomolecular complexes. This book caters to students and researchers in the area of biotechnology, microbiology, and pharmaceutical sciences.
    Type of Medium: Online Resource
    Pages: IX, 355 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811625169
    DDC: 660.6
    Language: English
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  • 82
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Zoology. ; Nanobiotechnology. ; Botany. ; Biomedical Research. ; Zoology. ; Nanobiotechnology. ; Plant Science.
    Description / Table of Contents: 1 Green nanotechnology: an overview -- 2 The Nano-Domain -- 3 Tools and Techniques Used in Nanobiotechnology -- 4 Green Synthesis of Nanoparticles -- 5 Biological Synthesis of Nanoparticles: Bacteria -- 6 Biological Synthesis of Nanoparticles: Fungi -- 7 Biological Synthesis of Nanoparticles: Algae -- 8 Biological Synthesis of Nanoparticles: Bryophytes -- 9 Biological synthesis of nanoparticles: Pteridophytes -- 10 Biological Synthesis of Nanoparticles: Gymnosperms -- 11 Biological Synthesis of Nanoparticles: Angiosperms- Monocotyledons -- 12 Biological Synthesis of Nanoparticles: Dicotyledons -- 13 Biological Synthesis of Nanoparticles: Animal Systems -- 14 Applications of Biosynthesized Nanoparticles -- 15 Toxicity Aspects of Biologically Synthesized Nanoparticles -- 16 Nanobiotechnology: Present Status and Future Prospects.
    Abstract: This book discusses the fundamental concepts of the green synthesis of nanoparticles and presents the latest advances in this emerging field. Providing a comprehensive overview of developments related to nanoparticle synthesis using fungi, algae, bryophytes, pteridophytes, gymnosperms, monocotyledons, dicotyledonous (angiosperms) and animal systems, it also explores techniques for the characterization of these nanoparticles. Lastly, it reviews the applications and toxicity of biologically synthesized green nanoparticles. Given its scope, it is a valuable resource for students, researchers and policymakers working in the field of nanobiotechnology and nanoscience.
    Type of Medium: Online Resource
    Pages: XIII, 352 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811671067
    DDC: 610.72
    Language: English
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  • 83
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Therapeutics. ; Pharmaceutical chemistry. ; Biomaterials. ; Pharmacology. ; Translational Research. ; Therapeutics. ; Pharmaceutics. ; Biomaterials.
    Description / Table of Contents: Chapter 1. Marine biomaterials: resources, categories and applications -- Chapter 2. Cross-linked marine biopolymers for delivery of therapeutics -- Chapter 3. Chitosan and Chitooligosaccharides: Preparation, Characteristics and their Potential Application as Therapeutic Agents -- Chapter 4. Marine collagen for delivery of therapeutics -- Chapter 5. Marine Biopolymers for delivery of Gene -- Chapter 6. Hydrogel scaffolds based on alginate, gelatin, and 2-hydroxyethyl methacrylate for tissue regeneration -- Chapter 7. Tissue Engineering application of marine based materials -- Chapter 8. Marine biopolymer for theranostic applications -- Chapter 9. Marine biomaterials as carrier of drugs/biomolecules for management of bone disorders -- Chapter 10. Expanding Role of Marine Natural Compounds in Immunomodulation: Challenges and Future Perspectives -- Chapter 11. Marine origin Bioactive Peptides: novel advances in the therapeutic potential.
    Abstract: This book provides updated information on marine-based biomedical carriers and their therapeutic potential. Marine biomaterials and bio-based carriers show wide application in pharmaceutical and biomedical fields to deliver small and large molecules. Biomaterial-based composites, scaffolds, or matrix systems are sound systems for controlled and prolonged drug release in target sites and control the premature release of drugs or bioactive compounds. This book discusses essential topics such as the therapeutic potential of marine collagen, management of bone disorders, gene delivery, natural marine compounds in immunomodulation, theranostic applications, tissue engineering, and regeneration. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. Marine biomaterial-based systems are popular for tissue engineering and biomedical imaging. This book is ideal for industry experts, students, and researchers in pharmaceutical sciences and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 392 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811653742
    DDC: 615
    Language: English
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  • 84
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Diseases. ; Internal medicine. ; Biomedical Research. ; Diseases. ; Internal Medicine.
    Description / Table of Contents: Chapter 1: Sphingolipids and Cholesterol -- Chapter 2: Sphingolipids in adipose: kin or foe? -- Chapter 3: De novo sphingolipid biosynthesis in atherosclerosis -- Chapter 4: Serine Palmitoyltransferase Subunit 3 and Metabolic Diseases -- Chapter 5: Molecular mechanisms of sphingolipid transport on plasma lipoproteins -- Chapter 6: Sphingosine 1-phosphate metabolism and signaling -- Chapter 7: Sphingomyelin synthase family and phospholipase Cs -- Chapter 8: Sphingolipid metabolism and signaling in endothelial cell functions -- Chapter 9: Cholesterol metabolism in chronic kidney disease: physiology, pathologic mechanisms, and treatment -- Chapter 10: Sphingolipids and asthma -- Chaper 11: Manifold Roles of Ceramide Metabolism in Nonalcoholic Fatty Liver Disease and Liver Cancer -- Chapter 12: Drug development in the field of sphinogolipid metabolism -- Chapter 13: Rare diseases in glycosphingolipid metabolism.
    Abstract: This book provides an up-to-date review of the fundamentals of sphingolipid metabolism and its role in metabolic diseases. Focusing on the sphingolipid de novo synthesis pathway, the effect of sphingomyelin, ceramide, and sphingosine-1-phosphate, and linkage between sphingolipids and other lipids, such as cholesterol, it covers serine palmitoyltransferase, ceramide synthases, ceramidases, sphingosine kinases, and sphingomyelin synthases, and more. While highlighting how rare diseases related to abnormal glycosphingolipid metabolism, this publication introduces sphingolipid metabolism-related diseases, such as lung diseases and cancers, as well as sphingolipid circadian regulation. The book demonstrates advances and limitations of research on sphingolipid metabolism and its roles in metabolic diseases and other diseases. It offers graduate students and researchers a coherent overview of sphingolipids, as well as the limitations of current research in the field, and promotes further studies on metabolic diseases, as well as pharmaceutical research on drug discovery based on sphingolipid de novo synthase.
    Type of Medium: Online Resource
    Pages: VIII, 213 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811903946
    Series Statement: Advances in Experimental Medicine and Biology, 1372
    DDC: 610.72
    Language: English
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  • 85
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Plant molecular biology. ; Botanical chemistry. ; Stress (Physiology). ; Plants. ; Plant Physiology. ; Plant Molecular Biology. ; Plant Biochemistry. ; Plant Stress Responses.
    Description / Table of Contents: Chapter 1. An overview of roles of enzymatic and non-enzymatic antioxidants in plant -- Chapter 2. Functional Characterization of the Antioxidant Enzymes in Plants Exposed to Environmental Stresses -- Chapter 3. Gene expression and role of antioxidant enzymes in crop plants under stress -- Chapter 4. Proteomic and Genomic Approaches for Antioxidant Enzymes-Mediated Defence Analyses in Higher Plants -- Chapter 5. Genetic Engineering Applications in Inducing Stress Tolerance in Plants through Antioxidants -- Chapter 6. Kinase mediated signaling cascades in plants abiotic stress physiology -- Chapter 7. Plant peroxidases: biomarkers of environmental stresses and signaling in plants -- Chapter 8. Molecular mechanisms of superoxide dismutase (SODs)-mediated defense in controlling oxidative stress in plants -- Chapter 9. Glutathione in higher plants: biosynthesis and physiological mechanisms during heat and drought-induced oxidative stress. Chapter 10. Role of Tocopherol in Conferring Abiotic Stress Tolerance in Plants -- Chapter 11. Plant glutathione transferases and their role in the mitigation of abiotic stresses -- Chapter 12. Role of ascorbic acid in alleviating abiotic stress in crop plants -- Chapter 13. CRISPR/Cas Mediated Genome Editing Technologies in Plants for Stress Resilience -- Chapter 14. Decrypting drought stress tolerance of crop plants via photosynthesis and antioxidative defense mechanisms -- Chapter 15. Role of Brassinosteroids (BRs) in modulating antioxidative defense mechanism in plants growing under abiotic and biotic stress conditions -- Chapter 16. Selenium-mediated regulation of antioxidant defense system and improved heavy metals tolerance in plants -- Chapter 17. Antioxidant defense system in plants against biotic stress -- Chapter 18. Revisiting the crucial role of reactive oxygen species and antioxidant defense in plant under abiotic stress -- Chapter 19. Plant life under changing environment: An exertion of environmental factors in oxidative stress modulation -- Chapter 20. Beneficial role of phytochemicals in oxidative stress mitigation in plants.
    Abstract: This edited book highlights the molecular basis of various enzymatic and non-enzymatic antioxidants, defense mechanisms and adaptation strategies employed by plants to avoid the stressful conditions. Special focus is given to gene expression, omics and other latest technologies such as CRISPR-Cas mediated genome editing applications for defense related studies in plants. Environmental stresses such as drought, salinity or floods etc. induce the generation of reactive oxygen species (ROS) which causes severe damage to cell membrane integrity by accelerating lipid peroxidation. To counteract the detrimental effect of ROS, plants are inherited with an intricate and vibrant antioxidant defense system, comprised of enzymatic (catalase, peroxidase, superoxide dismutase, glutathione reductase, glutathione S-transferase, guaiacol peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase etc.), and non-enzymatic (glutathione, ascorbate, α-tocopherol, carotenoids, flavonoids etc.) antioxidants, which scavenge and/or reduce excess ROS and improve plant tolerance to various stresses. Stress tolerance in most crop plants is positively correlated with an efficient antioxidant system. Therefore, studying the efficiency of antioxidant defense systems in plants is necessary for facilitating the plant’s nature of adaptation against challenging environments. This book is of interest to teachers, researchers and academic experts. Also, the book serves as additional reading material for undergraduate and graduate students of biotechnology and molecular biology of plants.
    Type of Medium: Online Resource
    Pages: XVIII, 451 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811679810
    DDC: 571.2
    Language: English
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  • 86
    Keywords: Pharmacology. ; Medical care. ; Therapeutics. ; Neurology . ; Medicine Research. ; Biology Research. ; Pharmacology. ; Health Care. ; Therapeutics. ; Neurology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. A Complete Patent Analysis of Cannabis/Marijuana in Drug Delivery and Disease Conditions -- Chapter 2. Neuropharmacological Approaches to Modulate Cannabinoid Neurotransmission -- Chapter 3. Cannabinoids in Cancer: Cross-talk Between Cannabinoids and miRNAs -- Chapter 4. Cannabis As A Potent Therapeutic Agent For Pharmaceutical Drugs: Recent Advancement In Drug Discovery And Human Healthcare -- Chapter 5. Cannabinoid-Based Innovative Prophylactic and Therapeutic Interventions for Neuropathic Pain and Migraine -- Chapter 6. The Legality of Use and Consumption of Cannabis (Marijuana) in the United States of America -- Chapter 7. Cannabis in Healthcare: Ethnobotanical and Pharmaceutical Perspectives and Legal Status in Turkey and The Middle East -- Chapter 8. Understanding the Pharmacokinetics, Safety Profile, and Scope of the Concerned Issue to Evade the Consumption of Cannabis/Marijuana -- Chapter 9. Traditional Uses of Cannabis in The Middle East and The Pathway to Cannabis-Based Healthcare in Israel -- Chapter 10. Traditional and Modern Health Uses of Cannabis sativa L. in Africa and its Phytochemical and Pharmacological Profile -- Chapter 11. Traditional Claims on Cannabis: An Indian and Global Scenario -- Chapter 12. Cannabis (Bhanga) in Classical Text of Ayurveda: An Evidence-Based Rationale -- Chapter 13. Cannabis-Based Cosmetic Products and Their Uses -- Chapter 14. Cannabis as A Unique and Valuable Nutraceutical Formulation for the Current and Future Global Wellbeing -- Chapter 15. Traditional, Cultural, and Nutraceutical Aspects of Cannabis in India.
    Abstract: The book contains review articles providing a comprehensive overview of cannabis/marijuana’s diverse healing aspects in human healthcare (medicinal, nutraceutical, skincare, etc.). The research articles include the role of cannabis in cancer treatment, drug discovery, cosmeceutical potential, prophylactic and therapeutic use for treating neuropathic pain and migraine, pharmacokinetics, safety profile, and issues related to the consumption of cannabis/marijuana.Another salient feature of the book is a complete mapping and region- and sector-wise critical analysis of cannabis/marijuana patents on healthcare and future directions for the benefit of researchers and businesses/entrepreneurs interested in the rapidly advancing area of cannabis. The text describes cannabis/marijuana’s detailed legal aspects, production prospects, and applications for healthcare and recreational purposes in the USA. It traces the traditional roots of cannabis use in Turkey, Israel, the Middle East, Africa, and India. This unique compendium of articles will be useful as a reference book for students, researchers, academics, business houses, and all individuals interested in medicinal, nutraceutical, cosmeceutical, traditional, legal, and commercial aspects of cannabis usage.
    Type of Medium: Online Resource
    Pages: XIX, 319 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811688225
    DDC: 615
    Language: English
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  • 87
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Stress (Physiology). ; Plants. ; Plants Disease and pest resistance. ; Botanical chemistry. ; Plant Physiology. ; Plant Stress Responses. ; Plant Immunity. ; Plant Biochemistry.
    Description / Table of Contents: Chapter 1. Introduction to UV-B Radiation -- Chapter 2. UV-B & Its Climatology -- Chapter 3. UV-B: Curse or boon? -- Chapter 4. Major influence on photosynthetic performance under UV-B exposure -- Chapter 5. Solar UV-B and Primary Producers in Aquatic Ecosystems -- Chapter 6. UV B and Crop research from past to new age -- Chapter 7. Plant Responses: UV-B avoidance strategies -- Chapter 8. Interaction of Salicylate and Jasmonate on the UV-B Induced Changes in Physiological and Biochemical Activities of Crop Plants -- Chapter 9. UVR8 discovery: A new vision in UV-B research -- Chapter 10. UVR8 signaling, mechanism and integration with other pathways -- Chapter 11. Acclimation of photosynthetic apparatus to UV-B radiation -- Chapter 12. Role of UV- B in regulating performance of photosystem I and II -- Chapter 13. Relationships of Oxidative stress and Ultraviolet-B radiation in Plants -- Chapter 14. Uv-B Stress And Plant Sexual Reproduction -- Chapter 15. Crosstalk Between Melatonin And Nitric Oxide In Plant Development And Uv-B Stress Response -- Chapter 16. Interaction of UV –B with Terrestrial ecosystem.
    Abstract: This book is an inclusive collection of topics on research on UVB for its impact on plants with a focus on its use as an emerging technology for crop growth and protection. This book covers role of UV-B on biological systems, and its transformation from generic stressor to specific regulator. It also explores the past research in UVB studies and the changing mind-sets regarding UV-B in recent time with respect to the plant growth. It also explores the discovery of specific UV-B photoreceptor, UVR8 and UVR8 mediated plants responses. This book is of interest to teachers, researchers, agriculture scientists and plant physiologists. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences.
    Type of Medium: Online Resource
    Pages: IX, 352 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811936203
    Series Statement: Plant Life and Environment Dynamics,
    DDC: 571.2
    Language: English
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  • 88
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Stress (Physiology). ; Plants. ; Plant molecular biology. ; Plant physiology. ; Plant Stress Responses. ; Plant Molecular Biology. ; Plant Physiology.
    Description / Table of Contents: 1. Cereals under abiotic stress: An overview -- 2. Organic Solutes in Cereals under Abiotic Stress -- 3. Oxidative stress and antioxidant enzymes in cereals under abiotic stress -- 4. Maize: Role and Responses under Abiotic Stress -- 5. SORGHUM: ROLE AND RESPONSES UNDER ABIOTIC STRESS. 6. Rice: Role and Responses under Abiotic Stress -- 7. Oats: Role and responses under Abiotic Stress -- 8. Millets: Role and Responses under Abiotic Stress -- 9. Triticale (X Triticosecale Wittmack): Role and Responses under Abiotic Stress -- 10. Quinoa: Role and Responses under Abiotic Stress -- 11. Cereals and organic fertilizers under abiotic stress -- 12. Cereals and Phytohormones under Salt Stress -- 13. Cereals and Phytohormones under Drought Stress -- 14. Cereals and phytohormones under temperature stress -- 15. Cereals and Phytohormones under heavy metal stress -- 16. Cereals and phytohormones under mineral deficiency stress -- 17. Cereals and Phytohormones under UV stress -- 18. Cereals and phytohormones under ozone stress -- 19. Use of biostimulants to improve salinity tolerance in cereals -- 20. Use of biostimulants to improve drought tolerance in cereals -- 21. Heat stress in cereals and its amelioration by biostimulants -- 22. Use of biostimulants to increase heavy metal tolerance in cereals -- 23. Use of biostimulants to improve UV tolerance in cereals -- 24. Use of Biostimulants to Improve Ozone Tolerance in Cereals -- 25. Genome editing, miRNA-based approaches in cereals under abiotic stress -- 26. Nanotechnology and its role in cereal crops under abiotic stress.
    Abstract: This book is an elaborate account of the effects of abiotic stressors on cereals crops. It not only discusses the impacts of abiotic stress on the crops but also the physiological, biochemical, and molecular strategies applied in plant of cereal crops to alleviate the detrimental effects of abiotic stressors. The book also elaborates on various molecular response to the abiotic stress. It is a knowledgebase providing readers latest updates on development of high-performance diagnostics, stress induced responses, genomics, phenomics and metabolomics involved in abiotic stress tolerance of cereal food crops. The book is useful for plant scientists and research scholars. Post graduate students of agriculture sciences, plant physiology, botany and biochemistry also benefit from this compilation. .
    Type of Medium: Online Resource
    Pages: XV, 687 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951213
    DDC: 581.788
    Language: English
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  • 89
    Keywords: Agriculture. ; Stress (Physiology). ; Plants. ; Plant physiology. ; Plant biotechnology. ; Agriculture. ; Plant Stress Responses. ; Plant Physiology. ; Plant Biotechnology.
    Description / Table of Contents: Chapter 1. Role of Nanosensors and Bionanosesors in Crop Abiotic Stress -- Chapter 2. Role of Environment Stress Leaf Senescence and Crop productivity -- Chapter 3. Genomics in Enhancing Crop Productivity against Stresses -- Chapter 4. Transgenic plants: A Tool to Increase Crop Productivity Under Stress Environment -- Chapter 5. Breeding efforts for crop productivity in abiotic stress environment -- Chapter 6. Changing Environment and Crop Plant Breeding -- Chapter 7. Crop plants, abiotic stress, reactive oxygen species production, signaling and their consequences -- Chapter 8. Environment Stress Tolerance in Plants -Physiological Aspects -- Chapter 9. Role of hormones in crop plants root system architecture under changing environmental conditions -- Chapter 10. Water Logging Tolerance and Crop Productivity -- Chapter 11. Crop Adaptability to Excess Salts -- Chapter 12. Crop Scavenging Potential to Heavy Metals -- Chapter 13. Role of plant microbiome under stress environment to enhance crop productivity -- Chapter 14. Role of Effective Management of Harvested Crop to Increase Productivity under Stress Environment -- Chapter 15. Bioactive Compost for Managing Plant Growth under Stress Environment -- Chapter 16. Salicylic acid: Metabolism, Regulation and Functions in Crop Abiotic Stress Tolerance -- Chapter 17. JA and Abiotic Stress Tolerance -- Chapter 18. ABA: Metabolism, Regulation and Functions in Crop Abiotic Stress Tolerance -- Chapter 19. Polyamines: Metabolism, Regulation and Functions in Crop Abiotic Stress Tolerance -- Chapter 20. Agriculture for Combating Global Starvation -- Chapter 21. Land use and Biodiversity Conservation through Agroforestry -- Chapter 22. Challenges of Stressed Soil: A Case Study of Acid Soil. .
    Abstract: The book inculcates a holistic approach to improve crop productivity and quality for ensuring food security and nutrition to all. This warrants to identify various stress conditions prevalent globally and tailor crop adaptability and productivity to the maximum accordingly, employing physio-molecular modern tools and techniques with judicious amalgamation with conventional crop husbandry. As a result, the book chapters encompass diverse environmental factors, internal physio-molecular processes and their modulations with a final goal of expanding area under cultivation by utilization of constraint terrains of poor site quality and augmenting sustainable crop productivity and quality on the face of rapidly changing climate. The book includes role of plant hormones, nano-sensors, nanomaterials etc. in stress tolerance responses, capturing recent advancement in the field of stress tolerance, enlarging scope of coverage by gleaning modern literature and providing glimpses of futuristic scenario of agriculture practices that can render ‘balance staple food rich in nutrition, vitamins and minerals’ to teeming billions of global human populations. Thus, the book provides a comprehensive overview of the role of stress environment and understanding stress physiology for developing stress tolerant crops. The book covers current knowledge and future prospects to achieve enhanced food security under stress environment of crops. The renowned contributors elegantly crafted each chapter, suited alike to both classroom texts for graduate students and reference material for researchers. The language and style are simple and lucid with liberal use of illustrations. This book should be on the shelf of university/ personal libraries for inquisitive students and enlightened researchers.
    Type of Medium: Online Resource
    Pages: XII, 402 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811663611
    DDC: 630
    Language: English
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  • 90
    Keywords: Agriculture. ; Agronomy. ; Agricultural biotechnology. ; Plant physiology. ; Agriculture. ; Agronomy. ; Agricultural Biotechnology. ; Plant Physiology.
    Description / Table of Contents: Chapter 1. Improving chickpea genetic gain under rising drought and heat stress using breeding approaches and modern technologies -- Chapter 2. Breeding chickpea for climate resilience: An overview -- Chapter 3. Reduction of Phytic Acid and Enhancement of Bioavailable Micronutrients in Common Beans (Phaseolus vulgaris L.) in Changing Climatic Scenario -- Chapter 4. Developing climate resilient Cowpea (Vigna unguiculata [L].Walp) through genomics-assisted breeding approaches -- Chapter 5. Fenugreek, a legume spice and multi-use crop adapted to a changing climate -- Chapter 6. Grass pea an inherent abiotic stress tolerant legume: Current status and future scope under changing environment -- Chapter 7. Breeding groundnut cultivars for resilience to climate change effects -- Chapter 8. Horse gram, an underutilized climate-resilient legume: Breeding and genomic approach for improving future genetic gain -- Chapter 9. Understanding abiotic stress responses in lentil under changing climate regimes -- Chapter 10. Approaches towards developing heat and drought tolerance in Mungbean -- Chapter 11. A Review on Stress Physiology and Breeding Potential of an underutilized, multipurpose legume: Rice Bean (Vigna umbellata) -- Chapter 12. Physiological Traits Based Breeding to Achieve Higher Yield in soybean Crop -- Chapter 13. Sunnhemp-A Climate Smart Crop.
    Abstract: This edited book covers all aspects of grain legumes including negative impact of abiotic and biotic stresses under the changing global climate. It discusses the role of various subject disciplines ranging from plant breeding, genetics, plant physiology, molecular biology, and genomics to high-throughput phenotyping and other emerging technologies for sustaining global grain and fodder legume production to alleviate impending global food crises. The book offers strategies to ensure plant-based dietary protein security across the globe. It covers all major commercial legume crops used as food, feed and fodder. This book is targeted to graduate and postgraduate students, researchers, progressive farmers and policymakers to inform them of the importance of cultivating grain and fodder legumes for future global food and nutritional security and for maintaining sustainable ecosystem.
    Type of Medium: Online Resource
    Pages: VIII, 327 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811698484
    DDC: 630
    Language: English
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  • 91
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Virology. ; Medical informatics. ; Biomedical Research. ; Bioinformatics. ; Virology. ; Health Informatics.
    Description / Table of Contents: Chapter 1. Databases, Knowledgebases and Software Tools for Virus Informatics -- Chapter 2. Detection and Prevention of Virus Infection -- Chapter 3. Bioinformatics for the Origin and Evolution of Viruses -- Chapter 4. In silico Drug Discovery for Treatment of Virus Diseases -- Chapter 5. Vaccines and Immunoinformatics for Vaccine Design -- Chapter 6. Predicting the Disease Severity of Virus Infection -- Chapter 7. Modeling the Virus Infection at the Population Level -- Chapter 8. Health-Based Geographic Information Systems for Mapping and Risk Modeling of Infectious Diseases and COVID-19 to Support Spatial Decision-Making -- Chapter 9. 5G, Big data and AI for Smart City and Prevention of Virus Infection.-.
    Abstract: This book introduces the translational informatics applied to most aspects of virus infection, including tracking of virus origin, detection and prevention of infection, drug discovery, and vaccine design as well as smart city-level monitoring and controlling of the virus epidemic by government. It covers the informatics for data mining and modelling at molecular, tissue/organ, individual, and population levels. The informatics for immunological mechanisms and the personalized prediction and treatment of infected patients are also summarized. The perspectives on the application of artificial intelligence to the prevention of virus outbreaks are also given. This book will be helpful to readers who are interested in prevention of virus infection, biomedical informatics, and artificial intelligence in medicine and healthcare.
    Type of Medium: Online Resource
    Pages: VII, 218 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689697
    Series Statement: Advances in Experimental Medicine and Biology, 1368
    DDC: 610.72
    Language: English
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  • 92
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Human physiology. ; Life sciences. ; Pharmacology. ; Biomedical Research. ; Human Physiology. ; Life Sciences. ; Pharmacology.
    Description / Table of Contents: Chapter 1: HDL Structure -- Chapter 2: HDL and Cholesterol ester transfer protein (CETP) -- Chapter 3: HDL and Endothelial Function -- Chapter 4: HDL and lipid metabolism -- Chapter 5: HDL and oxidation -- Chapter 6: Scavenger Receptor Class B Type I and HDL -- Chapter 7: ABCA1, ABCG1 and cholesterol homeostasis -- Chapter 8: HDL and ASCVD -- Chapter 9: HDL and Diabetes -- Chapter 10: HDL and sepsis -- Chapter 11: HDL mimetic peptides -- Chapter 12: HDL and microRNAs -- Chapter 13: HDL-kidney diseases -- Chapter 14: HDL and therapy -- Chapter 15: High-density lipoprotein and Surgery.
    Abstract: This book focuses on both high-density lipoproteins (HDL) metabolism and related diseases from the perspectives of the world-class experts in HDL. Several chapters in this book provide the overall information about HDL metabolism via detailed discussion of HDL structures as well as several key molecules involved in its functions, such as SR-B1 and Cholesteryl Ester Transfer Protein Inhibitors and so on. The rest of this book illustrates the connection between HDL and several diseases that are the major concerns of people’s health in many countries, and devotes to exploring the therapies of HDL related diseases. With a better understanding of the HDL metabolism and diseases, this book will benefit the audiences with interest in HDL from biomedicine to clinical practice.
    Type of Medium: Online Resource
    Pages: X, 195 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811915925
    Series Statement: Advances in Experimental Medicine and Biology, 1377
    DDC: 610.72
    Language: English
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  • 93
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Agriculture. ; Agricultural biotechnology. ; Plant physiology. ; Botany. ; Agriculture. ; Agricultural Biotechnology. ; Plant Physiology. ; Plant Science.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Potassium Dynamics in Soils -- Chapter 3. Potassium in Plants -- Chapter 4. Phytoavailability of Potassium -- Chapter 5. Potassium Evaluation in Soils -- Chapter 6. Potash For Quality Of Agricultural Commodities -- Chapter 7. Potassium Biofortification And Human Nutrition -- Chapter 8. Potash Research In Pakistan -- Chapter 9. Use Of Potash In Pakistan -- Chapter 10. Strategies To Improve Potash Use In Pakistan -- Chapter 11. Future Research Perspectives.
    Abstract: This book covers the use and dynamics of potassium fertilizers in agriculture. It explores potassium dynamics in soil, phytoavailability, uptake and translocation in crop plants, impact of potassium fertilizers on quality of agricultural produce. Potassium is an essential plant nutrient that has long been overlooked in agriculture of many developing countries. In most of the agro-ecosystems of such countries, potassium balance is negative because its application seldom matches with crop removal. Agro-technicians lack enough skills and resources to promote the right source of fertilizer at the right rate, time and place to facilitate profitable farming. There is a need for farmers to update their farming practices so as to improve the crop yield and quality under unfavorable climatic conditions. Correct application of potassium fertilizers is directly linked with increased crop yield per unit land area in most of the developing countries. Therefore this book fills the gap in the information and provide the readers with latest updates on use of potassium fertilizers. This book contains latest information relevant for graduate students, progressive farmers, extension worker, early career researchers, and policy makers.
    Type of Medium: Online Resource
    Pages: XVII, 124 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811668838
    DDC: 630
    Language: English
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  • 94
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Virology. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Virology. ; Medical Microbiology. ; Biomedical Research.
    Description / Table of Contents: Peptide virus entry inhibitors: past, present and future -- Small-molecule virus entry inhibitors -- Human endogenous virus entry inhibitors -- Lipopeptide HIV entry inhibitors -- Peptide HIV entry inhibitors targeting gp41 NHR -- Small-molecule HIV entry inhibitors targeting gp41 MPER -- Small-molecule HIV entry inhibitors targeting CD4-binding site in gp120 -- Small-molecule HIV entry inhibitors targeting gp120 -- SARS-CoV, MERS-CoV, and pan-coronavirus entry inhibitors -- Hendra virus (HeV) and Nipah virus (NiV) entry inhibitors -- Ebola virus entry inhibitors -- Cyclo-peptide-based Ebola virus entry inhibitors -- Influenza virus entry inhibitors -- Parainfluenza virus entry inhibitors -- Zika virus entry inhibitors -- HBV entry inhibitors -- HBV and HDV entry inhibitors -- HCV entry inhibitors -- Protein-based HPV entry inhibitors.
    Abstract: This book focuses on the important discoveries of the small molecule-, peptide-, and protein-based virus entry inhibitors and discusses advance of the development of different type of virus entry inhibitors as a novel class of antiviral drugs for treatment and prevention of viral infection. It includes entry inhibitors of HIV,HeV, NiV, RSV, EBOV, HCoV, HBV, HCV, HDV, HPV, flavivirus and influenza virus, so on. This book aims at providing an updated knowledge on virus entry inhibitors.
    Type of Medium: Online Resource
    Pages: X, 239 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811687020
    Series Statement: Advances in Experimental Medicine and Biology, 1366
    DDC: 579.2
    Language: English
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  • 95
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Data mining. ; Application software. ; Biomedical Research. ; Bioinformatics. ; Data Mining and Knowledge Discovery. ; Computer and Information Systems Applications.
    Description / Table of Contents: Chapter 1. Integrative Bioinformatics: History and Perspective -- Chapter 2. From Genotypes to Phenotypes - A Plant Perspective on Current Developments in Data Management and Data Publication -- Chapter 3. Research data resources for epidemiology -- Chapter 4. Data Warehousing of Life Science Data -- Chapter 5. Automation in Graph-Based Data Integration and Mapping -- Chapter 6. DaTo: an Integrative Web Portal for Biological Databases and Tools -- Chapter 7. The Use of Data Integration and Knowledge Graphs in Modern Molecular Plant Breeding -- Chapter 8. Integrative data analysis and exploratory data mining in biological knowledge graphs -- Chapter 9. Exploring plant transcription factor regulatory networks -- Chapter 10. Microbiome and big-data mining -- Chapter 11. Data Integration Applications in Medical Information Systems -- Chapter 12. Visualising Metabolic Pathways and Networks: Past,Present,Future -- Chapter 13. Comprehensive open-source Petri net toolchain for modeling and simulation in systems biology -- Chapter 14. Immersive Exploration of Cell Localization Scenarios using VR, Spatialized Video Communication and Integrative Bioinformatics -- Chapter 15. IoS: a Needed Platform for Scientific Workflow Management -- Chapter 16. Revealing genotype-phenotype interactions: The AgroLD experience and challenges -- Chapter 17. Interactive Data Analyses Using Tbtools -- Chapter 18. Analyzing multi-omic data with integrative platforms.
    Abstract: This book provides an overview of the history of integrative bioinformatics and the actual situation and the relevant tools. Subjects cover the essential topics, basic introductions, and latest developments; biological data integration and manipulation; modeling and simulation of networks; as well as a number of applications of integrative bioinformatics. It aims to provide basic introduction of biological information systems and guidance for the computational analysis of systems biology. This book covers a range of issues and methods that unveil a multitude of omics data integration and relevance that integrative bioinformatics has today. It contains a unique compilation of invited and selected articles from the Journal of Integrative Bioinformatics (JIB) and annual meetings of the International Symposium on Integrative Bioinformatics.
    Type of Medium: Online Resource
    Pages: XI, 386 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811667954
    DDC: 610.72
    Language: English
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  • 96
    Keywords: Microbiology. ; Pharmacology. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Microbiology. ; Pharmacology. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Biopesticides in sustainable agriculture: current status and future prospects -- Chapter 2. Entomopathogenic Fungi: Current Status and Prospects -- Chapter 3. Utilization of Entomopathogenic Bacteria for modern insect pest management -- Chapter 4. Entomopathogenic Nematodes (EPNs): A Green Strategy for Management of Insect-Pests of Crops -- Chapter 5. Trends in neem (Azadirachta indica)-based botanical pesticides -- Chapter 6. Role of Plant Essential Oils in Pest Management -- Chapter 7. Plant Secondary Metabolites: Emerging Trends in Agricultural Pests Control -- Chapter 8. Transgenic plants and its role in insect control -- Chapter 9. Improving Insect Control Using Genetically Modified Entomopathogens -- Chapter 10. Importance of metabolic enzymes and their role in insecticide resistance -- Chapter 11. Insect microbiota and host immunity: An emerging target for pest control.-Chapter 12. Eco-smart Biorational Approaches in Housefly Musca domestica L. 1758 Management.
    Abstract: This book discusses different approaches for successful pest-management through biotechnological interventions. Pest management is directly associated with the agricultural productivity. The book introduces the reader to various kinds of biopesticides that have been developed and are being developed for field application. Chemical pesticides have been widely used to control pests, and these induce pesticide resistance as well as other environmental problems. This book discusses the necessity to develop alternate pest control strategies, especially environment-friendly and target-specific biopesticides against destructive pests. The book describes important aspects such as microbial biopesticides, plant-based biopesticides, natural products that act against pests and the various other biotechnological advances and limitations of these biopesticides. It provides an in-depth knowledge of the latest research and development in the area of biopesticides. This informative book is meant for students and researchers in the fields of biotechnology, agriculture and applied microbiology.
    Type of Medium: Online Resource
    Pages: VIII, 303 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811639890
    DDC: 579
    Language: English
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  • 97
    Keywords: Medicine Research. ; Biology Research. ; Natural products. ; Food science. ; Agriculture. ; Pharmaceutical chemistry. ; Biomedical Research. ; Natural Products. ; Food Science. ; Agriculture. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. Plant peptides as protease inhibitors for therapeutic and agricultural applications -- Chapter 2.Plant peptides as protease inhibitors for therapeutic and agricultural applications -- Chapter 3.Bioactive α- Amylase Inhibitors: Sources, Mechanism of Action, Biochemical Characterization and Applications -- Chapter 4.Recent Updates on In silico Screening of Natural Products as Potential Inhibitors of Enzymes of Biomedical and Pharmaceutical Importance -- Chapter 5.H+/K+-ATPase inhibitors from plants: A potential source for drug discovery -- Chapter 6.Use of protease inhibitors as a promising alternative for pest control -- Chapter 7. Pancreatic lipase (PL) inhibitors from medicinal plants and their potential applications in the management of obesity -- chapter 8. Bioactive peptides and polysaccharides- Setting a new trend in replacing conventional angiotensin-converting enzyme inhibitors -- Chapter 9.Natural Protease Inhibitors and their Therapeutic Potentials against SARS-CoV-2 -- Chapter 10. Telomerase and its inhibitor in cancer therapeutics: Current status and future prospective -- Chapter 11.Metal nanomaterials as enzyme inhibitors and their applications in agriculture and pharmaceutical -- Chapter 12.α-glucosidase inhibitors for diabetes/blood sugar regulation.
    Abstract: This book provides an overview of the latest developments and future challenges in enzyme inhibitor research. It discusses the general enzyme inhibitory principles and mechanisms in enzyme activity regulation and application of enzyme inhibitors in different areas and sectors. The major areas of applications of enzyme inhibitors covered in this book are human health management, agriculture, food processing and research, which leads to drug discovery or enzyme activity mechanisms. The book also identifies the gaps in the existing knowledge and opens up new research ideas in this important area. Currently, most enzyme inhibitors are reported to inhibit various classes of enzymes. These enzyme inhibitors are the focus of the scientific community because they may answer an increasing array of questions in the research area of biological sciences, including biochemistry, medicine, physiology, pharmacy, agriculture, ecology etc. It also serves as a useful tool in the study of enzyme structures and reaction mechanisms and in the development of technologies in agriculture, food processing, and health management. Chapters in this book cover topics such as plant-derived inhibitors of serine proteases, pancreatic lipase (PL) inhibitors from indigenous medicinal plants, amylase inhibitors and their applications in agriculture and food processing industries and advances in silico techniques used in the study of enzyme inhibitors. The book will serve as a valuable resource for students and researchers in Life Sciences, agriculture, medicine, food processing, and allied industries. .
    Type of Medium: Online Resource
    Pages: XII, 283 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811909320
    DDC: 610.72
    Language: English
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  • 98
    Keywords: Plant physiology. ; Stress (Physiology). ; Plants. ; Plant molecular biology. ; Botanical chemistry. ; Plant biotechnology. ; Plant Physiology. ; Plant Stress Responses. ; Plant Molecular Biology. ; Plant Biochemistry. ; Plant Biotechnology.
    Description / Table of Contents: Heat stress in wheat: adaptation strategies -- Molecular markers mediated heat stress tolerance in crop plants -- Physiology of crop yield under heat stress -- Physiological traits for improving heat stress tolerance in plants -- Understanding the mechanism of high temperature stress effect and tolerance in wheat -- Reactive Oxygen Species – Friend or Foe -- CDPKs based signalling network: Protecting the wheat from heat -- Heat Shock Proteins: Catalytic Chaperones involved in Modulating Thermotolerance in Plants -- Starch metabolism under heat stress -- Heat stress and grain quality -- Omics tools and techniques for study of defense mechanism in plants -- Induced mutagenesis for high temperature tolerance in crop plants -- CRISPR/Cas-based genome editing to enhance heat stress tolerance in crop plants -- Genomics-enabled breeding for heat and drought stress tolerance in crop plants.
    Abstract: This book collates various aspects of stress tolerance in crop plants. It primarily focuses on the heat and temperature related stress, starting from the severity of the problem on quantity and quality of yield under the threat of global climate change. The content also explores other mechanistic dimensions such as physiochemical and molecular mechanism underlying thermotolerance, signaling mechanism under heat stress, role of heat shock proteins in modulating thermotolerance, omics approach for development of climate smart-crop. Chapters discuss different approaches used in the past to develop heat stress tolerant crop plants, list of developed thermotolerant agriculturally important crop plants, redox homeostasis under heat stress, nutrient uptake and use efficiency in plants under heat stress and much more. The book is a useful compilation for researchers working in the area of abiotic stress tolerance in crop plants, as well as for students of plant physiology and agricultural sciences.
    Type of Medium: Online Resource
    Pages: XIII, 321 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811938009
    DDC: 571.2
    Language: English
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  • 99
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant physiology. ; Stress (Physiology). ; Plants. ; Agriculture. ; Botany. ; Plant Physiology. ; Plant Stress Responses. ; Agriculture. ; Plant Science.
    Description / Table of Contents: Chapter 1. Effect of low temperature stress on germination, growth and phenology of plants: A review -- Chapter 2. Plant water relationship under low temperature stress: A review -- Chapter 3. Effect of low temperature stress on photosynthesis and allied traits: A review -- Chapter 4. Low temperature stress and nitrogen metabolism in plants: A review -- Chapter 5. Lipid metabolism in plants under low temperature stress -- Chapter 6. Plant growth hormones in plants under low temperature stress: A review -- Chapter 7. Effect of low temperature on dry matter, partitioning and seed yield: A review.
    Abstract: This book is a collection of comprehensive reviewed chapters covering major physiological aspects, both production as well as biochemical aspects, of a plant under low temperature stress. Low temperature stress has been dealt in two parts, first between 10 to 00 C and secondly between 0 to -400 C. This book highlights the physiological aspects of plants under low temperature stress and explains the various adaptive measures plants undergo to tolerate low temperature stress. Essential information is provided on germination, growth and development, dry matter accumulation, partitioning and final yield of a crop plant. As physiology deals with morphological and biochemical aspect of all the basic processes, therefore an in depth understanding the major physiological issues in plants under high temperature will help plant breeders to tailor different crop plants with desirable physiological traits to do better under higher temperature. The present book is intended to cover the effects of low temperature stress on the various physiological aspects in plants. Not only in production physiology, this book also deals with major biochemical processes, like photosynthesis, nitrogen and lipid metabolism, mineral nutrition and plant growth hormones. Efforts have been made deal with different measures to mitigate the effects of low temperature stress on plants. This book will be an asset for post graduate students, faculty members, researchers engaged in not only in physiological studies but also agronomy, plant breeding and like subjects. In depth analysis of the major physiological processes in plants under low temperature stress that are presented in this book will help plant breeders for tailoring crops for desirable physiological traits needed to survive and to give better economic return under the threats of low temperature stress. This book is also helpful for policy planners and industries engaged in agribusiness in short term as well as long term gain.
    Type of Medium: Online Resource
    Pages: XIX, 734 p. 31 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811690372
    DDC: 571.2
    Language: English
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  • 100
    Keywords: Plant genetics. ; Plant biotechnology. ; Botanical chemistry. ; Plant physiology. ; Agriculture. ; Biomaterials. ; Nucleic acids. ; Plant Genetics. ; Plant Biotechnology. ; Plant Biochemistry. ; Plant Physiology. ; Agriculture. ; Nucleic Acid.
    Description / Table of Contents: Chapter 1.Genetic tinkering of crops for sustainable development – 2020 and Beyond -- Chapter 2.Genetic improvement of rice for food and nutritional security 3.Improvement of wheat (Triticum spp.) through gene manipulation -- Chapter 4. Transgenic finger millet [Eleusine coracana (L.) Gaertn.] for crop improvement -- Chapter 5. Transgenic pigeon pea [Cajanus cajan (L). Millsp.] -- Chapter 6. Genetically engineered chickpea: Potential of an orphan legume to achieve food and nutritional security by 2050 -- Chapter 7. Progress in genetic engineering of cowpea for insect pest and virus resistance -- Chapter 8. Peanut (Arachis hypogaea L.) transgenic plants for abiotic stress tolerance -- Chapter 9. Genetic engineering of sunflower (Helianthus annuus L.) for important agronomic traits -- Chapter 10. Genetic engineering in safflower (Carthamus tinctorius L.): Retrospect and prospect -- Chapter 11. Nutritional value, in vitro regeneration and development of transgenic Cucurbita pepo and C. maxima for stress tolerance: An overview -- Chapter 12. Sugarcane transgenics: Developments and opportunities .
    Abstract: Genetic transformation is a key technology, in which genes are transferred from one organism to another in order to improve agronomic traits and ultimately help humans. However, there is apprehension in some quarters that genetically modified crops may disturb the ecosystem. A number of non-governmental organizations continue to protest against GM crops and foods, despite the fact that many organisms are genetically modified naturally in the course of evolution. In this context, there is a need to educate the public about the importance of GM crops in terms of food and nutritional security. This book provides an overview of various crop plants where genetic transformation has been successfully implemented to improve their agronomically useful traits. It includes information on the gene(s) transferred, the method of gene transfer and the beneficial effects of these gene transfers and agronomic improvements compared to the wild plants. Further, it discusses the commercial prospects of these GM crops as well as the associated challenges. Given its scope, this book is a valuable resource for agricultural and horticultural scientists/experts wanting to explain to the public, politicians and non-governmental organizations the details of GM crops and how they can improve crops and the lives of farmers.
    Type of Medium: Online Resource
    Pages: XIII, 265 p. 14 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811558979
    DDC: 581.35
    Language: English
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