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  • thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics  (56)
  • History
  • bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
  • Frontiers Media SA  (83)
  • Archaeopress Publishing Ltd
  • English  (109)
  • Spanish  (2)
  • Latin
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  • English  (109)
  • Spanish  (2)
  • Latin
  • Arabic  (1)
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  • 1
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: precise genome editing ; CRISPR ; HDR efficiency ; biallelic HDR targeting ; off-target effect ; animal model ; base editing ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 2
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    Archaeopress Publishing Ltd
    Publication Date: 2024-04-02
    Description: Western Mesoamerican Calendars and Writing Systems draws together studies by some of the world’s leading experts presented at a conference held in December 2020, ‘The Origins and Developments of Central Mexican Calendars and Writing Systems’. Mesoamerica is one of the few places to witness the independent invention of writing. From the earliest attestations of this intellectual feat in the Late Preclassic period 900 bc-ad 150), writing spread throughout Mesoamerica, developing and diversifying into a series of distinct and independent scripts. With the exception of the celebrated phonetic decipherments of Maya and Aztec writing, which are now well-documented and can be fully read, most Mesoamerican writing systems remain little studied and undeciphered. This is particularly true of the writing systems of Western Mesoamerica, the topic of this volume.Bringing together new research on Western Mesoamerican writing systems, some contributions focus on specific features of a given writing system, whereas others offer state-of-the-art syntheses of whole writing systems. Two contributions focus on the calendar in particular, and associated notations, as integral parts of writing systems. Chapters are included on the writing system of Teotihuacan, the Ñuiñe writing of the Mixteca Baja and adjoining areas, the writing system of the Epiclassic period and Aztec writing of the Postclassic. These writing systems represent more than a millennium of written records and literacy in Mesoamerica, spanning from the Early Classic to the Late Postclassic (from the 2nd to the sixteenth centuries ad). Aztec writing even continued in use for several decades after the Spanish invasion of Mexico (ad 1519-1521), which saw the introduction of the Latin alphabet and the gradual obsolescence of Mesoamerican logophonetic writing systems.
    Keywords: History ; Latin America ; Pre-columbian Era ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 3
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: enhancement ; genetics ; therapeutics ; CRISPR ; editorial ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 4
    Publication Date: 2023-12-20
    Description: Intracellular pathogens, such as bacteria and parasites, have evolved specialized mechanisms to survive and replicate in their host, leading to disorders and diseases. The principle of these mechanisms is to reprogram the microbicidal cell function in order to disable the host cells defence that aims to control and eliminate foreign invaders. Devoid of their defence, cells become permissive to pathogens invasion. The aim of this Research Topic is to highlight and cover recent understanding of mechanisms and molecules used by pathogens to interfere with the microbicidal function of cells. This Research Topic will focus on the reprogramming of the cellular dynamics, the immune response, the phagolysosome biogenesis and the signal transduction pathways bypathogens. Special attention will be made on non-proteic virulence factors, however this Research Topic is not restricted to non-proteic virulence factors.
    Keywords: Q1-390 ; RC109-216 ; rab ; RNAi ; Ubiquitination ; host-pathogens interaction ; Coxiella ; Brucella ; Planarians ; Body Lices ; mycobacteria ; granulomas ; Leshmania ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 5
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords:  Viruses ; Genetics ; Host-virus interaction ; Epidemiology ; Immunity ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 6
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    Archaeopress Publishing Ltd
    Publication Date: 2024-04-04
    Description: Suburbia and Rural Landscapes in Medieval Sicily presents the results of the main ongoing archaeological and historical research focusing on medieval suburbia and rural sites in Sicily. It is thus intended to update traditional views regarding the evolution of this territory from Late Antiquity to the Middle Ages by bringing into the picture new data from archaeological excavations undertaken at several sites across Sicily, new information from surveys of written sources, and new reflections based on the analysis of both material and documentary sources. The volume is divided into thematic areas: Urbanscapes, suburbia, hinterlands; Inland and mountainous landscapes; Changes in rural settlement patterns; and Defence and control of the territory. The essays underline the fundamental contribution of archaeological research in Sicily to the debate on the formation of early medieval landscapes at the crossroads between the Byzantine and Islamic worlds. A comparison with other research areas and constant dialogue with historical sources constitute essential elements for advancing our knowledge of the rural and suburban world of Sicily as a case study illustrating wider Mediterranean dynamics.
    Keywords: Social Science ; Archaeology ; History ; Europe ; Medieval ; thema EDItEUR::N History and Archaeology::NK Archaeology ; thema EDItEUR::N History and Archaeology::NH History::NHD European history
    Language: English
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  • 7
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    Archaeopress Publishing Ltd
    Publication Date: 2024-03-28
    Description: The appearance of new media and its enormous diffusion in the last decades of the 20th century and up to the present has greatly increased and diversified the reception of Egyptian themes and motifs and Egyptian influence in various cultural spheres. So-called ‘popular’ or ‘pop’ culture (cinema, genre fiction, TV-series, comics, graffiti, computer and video games, rock and heavy music, radio serials, among others) often makes use of narratives and motifs drawn from the observation and study of ancient Egypt, updated and reinterpreted in various ways, and which is now the subject of study by scholars of Egyptology. The present monograph seeks to provide new evidence of this interdisciplinarity between Egyptology and popular culture. It explores the conscious reinterpretation of the past in the work of contemporary authors, who shape an image of the Egyptian reality that in each case is determined by their own circumstances and contexts.
    Keywords: Social Science ; Media Studies ; History ; Ancient ; Egypt ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCT Media studies ; thema EDItEUR::N History and Archaeology::NH History::NHC Ancient history
    Language: English
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  • 8
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    Archaeopress Publishing | Archaeopress Publishing Ltd
    Publication Date: 2024-04-02
    Description: The Delta Survey Workshop comprises the proceedings of two conferences organised by the Delta Survey Project and held in Alexandria in 2017 and Mansoura in 2019. The 23 papers contain the results of the latest fieldwork in the Nile Delta and Sinai, from survey work that records and documents unknown and new sites such as Kom Dabaa and Mutubis or sites in Kafr Dawar and Wadi Tumilat, to excavation reports from established projects at major sites such as Qantir, Bubastis, Tell Heboua, Tell el-Maskhuta, Akademia, Taposiris Magna and Tell Fara’in (Buto). New work is also reported from Tell Tebilla, urban funerary sites in Alexandria, and Arab el Hisn (Heliopolis). There are also thematically focussed papers covering ovens recorded in archaeological and ethnological fieldwork, tower houses, amphorae and pottery and human remains. In addition, there are mapping and remote sensing reports from Mariut and the Buto area, rock inscriptions in Sinai and a catalogue project of material in the St Mark antiquities collection in Alexandria.
    Keywords: History ; Ancient ; Egypt ; thema EDItEUR::N History and Archaeology::NH History::NHC Ancient history
    Language: English
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  • 9
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    Archaeopress Publishing Ltd
    Publication Date: 2024-03-23
    Description: (Trans)missions: Monasteries as Sites of Cultural Transfers focuses on the Catholic tradition of consecrated life (vita religiosa) from the High Middle Ages to the present. It gathers papers by authors from various disciplinary backgrounds, in particular art history, history, anthropology and translation studies. Finally, it includes two short reports on Czech projects on monastic topics. The chronological and geographical scope of the book is focused on the Western tradition from the High Middle Ages up to the present, specifically in the territory of Central Europe and Spain along with its overseas colonies. The region of Central Europe was interconnected with the Spanish Empire through the Austrian and Spanish Habsburgs, allowing the given topic to be studied in a broader international context, and to involve the Central European and Spanish territories in the global flow of information, thus incorporating the regional and national histories of individual European countries into global history. This involvement is also enabled by the study of interconnecting themes, such as cultural transfers within and between the Old and the New World, information flows between the Spanish and Austrian Habsburgs, the processes of individual and social identity formation, representation and othering of women, and the missionary activities of mendicant orders in the New World, together with their translation practices; and by the contextualization of monastic history and related themes within the processes of European internal and external colonization and evangelization.
    Keywords: Art ; Subjects & Themes ; Religious ; History ; Medieval ; Religion ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGR Religious and ceremonial art ; thema EDItEUR::A The Arts::AG The Arts: treatments and subjects::AGA History of art ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRA Religion: general::QRAX History of religion
    Language: English
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  • 10
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    Frontiers Media SA
    Publication Date: 2023-12-20
    Description: Infectious disease is the result of an interactive relationship between a microbial pathogen and its host. In this interaction both the host and the pathogen attempt to manipulate each other using a complex network to maximize their respective survival probabilities. Programmed host cell death is a direct outcome of host-pathogen interaction and may benefit host or pathogen depending on microbial pathogenesis. Apoptosis and pyroptosis are two common programmed cell death types induced by various microbial infections. Apoptosis is non-inflammatory programmed cell death and can be triggered through intrinsic or extrinsic pathways and with or without the contribution of mitochondria. Pyroptosis is an inflammatory cell death and is typically triggered by caspase-1 after its activation by various inflammasomes. However, some non-canonical caspase-1-independent proinflammatory cell death phenomena have been reported. Microbial pathogens are able to modulate host apoptosis and pyroptosis through different triggers and pathways. The promotion and inhibition of host apoptosis and pyroptosis vary and depend on the microbe types, virulence, and phenotypes. For example, virulent pathogens and attenuated vaccine strains may use different pathways to modulate host cell death. Specific microbial genes may be responsible for the modulation of host cell death. Different host cells, including macrophages, dendritic cells, and T cells, can undergo apoptosis and pyroptosis after microbial infections. The pathways of host apoptosis and pyroptosis induced by different microbes may also differ. Different methods can be used to study the interaction between microbes and host cell death system. The articles included in this E-book report the cutting edge findings in the areas of microbial modulation of host apoptosis, pyroptosis and inflammasome.
    Keywords: Q1-390 ; RC109-216 ; microbial infection ; pyroptosis ; Mycobacterium tuberculosis ; bacterial exploitation of apoptosis ; Brucella ; Infectious Disease ; Inflammasome ; Legionella ; programmed cell death ; Apoptosis ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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