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  • History  (458)
  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences  (407)
  • RAND Corporation  (424)
  • MDPI - Multidisciplinary Digital Publishing Institute  (402)
  • Peter Lang International Academic Publishing Group  (35)
  • American Meteorological Society
  • Annual Reviews
  • Springer
  • English  (860)
  • German  (5)
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  • English  (860)
  • German  (5)
  • French  (1)
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  • 1
    Publication Date: 2024-04-02
    Description: As part of an effort to assist Chile in developing a strategic program to foster the development of the health information technology (health IT) sector over the next five to ten years, this report assesses the current state of health IT adoption and implementation in Chile, as well as the challenges and opportunities facing the sector over the coming years.
    Keywords: Health Sciences ; History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBQ Medicolegal issues
    Language: English
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  • 2
    Publication Date: 2024-04-04
    Description: This report shares an overview of the budget of the U.S. Department of Veterans Affairs (VA) and focuses particularly on health care spending and the Veterans Health Administration (VHA), including makeup of the veteran population, available health coverage, patterns of use, and potential areas of improvement.
    Keywords: History ; Health Sciences ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services
    Language: English
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  • 3
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-04
    Description: Gesellschaften mit starker Einwanderung kennzeichnen vielfältige Formen von Identitätsbildung und das Ringen um politische und zivilgesellschaftliche Partizipation. Dies gilt in besonderer Weise für Luxemburg im 19. und 20. Jahrhundert. Hier entstand in einem Kleinstaat eine der jüngeren Nationen Europas und zugleich eine besonders offene, plurikulturelle Einwanderungsgesellschaft. Ziel dieses Bandes ist es, die Entstehung dieser Mehr-Kulturen-Gesellschaft im europäischen Zusammenhang zu verstehen. Die einzelnen Beiträge analysieren mit Hilfe unterschiedlicher sozial- und kulturwissenschaftlicher Annäherungen exemplarische Konfliktlinien der Identitätsbildung und des Kampfes um Partizipation.
    Keywords: European history ; Biography: general ; Language teaching and learning ; History ; Social and cultural history ; General and world history ; Literature: history and criticism ; Literary studies: ancient, classical and medieval ; Literary theory ; Philosophy ; Politics and government ; Civics and citizenship ; Political science and theory ; Political control and freedoms ; Anthropology ; Social and cultural anthropology ; Ethnic studies ; Gender studies: women and girls ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history ; thema EDItEUR::N History and Archaeology::NK Archaeology ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSF Gender studies, gender groups::JBSF1 Gender studies: women and girls ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory
    Language: German
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  • 4
    Publication Date: 2024-03-29
    Description: This study provides a quantitative and qualitative status report on the implementation of school-based management (SBM) in Indonesia, identifies factors associated with the successful practices of SBM, and assesses SBM effects on student achievement eight years after inception. They found that the implementation so far has produced limited success and provide recommendations to strengthen the nation’s SBM practices.
    Keywords: Education ; History ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education::JNKC Curriculum planning & development ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education::JNKD Examinations & assessment ; bic Book Industry Communication::J Society & social sciences::JN Education::JNS Teaching of specific groups & persons with special educational needs::JNSV Teaching of students with English as a second language (TESOL) ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJF Asian history ; thema EDItEUR::J Society and Social Sciences::JN Education::JND Educational systems and structures::JNDG Curriculum planning and development ; thema EDItEUR::J Society and Social Sciences::JN Education::JND Educational systems and structures::JNDH Education: examinations and assessment ; thema EDItEUR::J Society and Social Sciences::JN Education::JNU Teaching of a specific subject ; thema EDItEUR::J Society and Social Sciences::JN Education::JNF Educational strategies and policy ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history
    Language: English
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  • 5
    Publication Date: 2024-03-29
    Description: The U.S. armed forces must be prepared to deploy to a wide range of locations and confront adversaries that span the threat spectrum. This report reviews selected findings from a study of Army and joint anti-access and area denial challenges and proposes a joint approach to countering these threats in future operations.
    Keywords: History ; Technology ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
    Language: English
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  • 6
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    RAND Corporation
    Publication Date: 2024-03-29
    Description: This RAND report examines the U.S. Army role in Southeast Asia. Under current benign conditions, efforts should focus on supporting defense reform, addressing transnational threats, and balancing China. If the outlook deteriorates, the United States should increase security cooperation, conclude new regional basing agreements, expand disaster assistance, and create policies to encourage risk-averse Chinese behavior.
    Keywords: History ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history
    Language: English
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  • 7
    Publication Date: 2024-04-02
    Description: The Department of Defense (DoD) has developed new sensor technologies to support U.S. forces in Iraq and Afghanistan; these technologies are potentially useful for counterdrug operations along the southern U.S. border, but there are legal questions regarding how they may be used and how sensor information may be shared between federal agencies in domestic operations. This report examines federal law and DoD policy to answer these questions.
    Keywords: History ; Technology ; Political Science ; thema EDItEUR::N History and Archaeology::NH History::NHH African history ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSD Diplomacy ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services::JKSW Emergency services::JKSW1 Police and security services ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
    Language: English
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Keywords: QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 9
    Publication Date: 2024-04-02
    Description: The Kurdistan Region of Iraq needs policy-relevant data to help improve infrastructure, encourage the private sector, attract foreign investment, and foster economic growth. The Kurdistan Region Statistics Office needs to build capacity to collect the data. RAND worked closely with the Office to build capacity by preparing, conducting, and analyzing the first round of a survey of the regional labor force.
    Keywords: History ; Sociology ; Law ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::L Law::LN Laws of specific jurisdictions and specific areas of law::LNH Employment and labour law: general ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
    Language: English
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  • 10
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    Springer Nature | Springer
    Publication Date: 2024-04-05
    Description: This open access textbook aims at providing detailed explanations on how to design and construct image analysis workflows to successfully conduct bioimage analysis. Addressing the main challenges in image data analysis, where acquisition by powerful imaging devices results in very large amounts of collected image data, the book discusses techniques relying on batch and GPU programming, as well as on powerful deep learning-based algorithms. In addition, downstream data processing techniques are introduced, such as Python libraries for data organization, plotting, and visualizations. Finally, by studying the way individual unique ideas are implemented in the workflows, readers are carefully guided through how the parameters driving biological systems are revealed by analyzing image data. These studies include segmentation of plant tissue epidermis, analysis of the spatial pattern of the eye development in fruit flies, and the analysis of collective cell migration dynamics. The presented content extends the Bioimage Data Analysis Workflows textbook (Miura, Sladoje, 2020), published in this same series, with new contributions and advanced material, while preserving the well-appreciated pedagogical approach adopted and promoted during the training schools for bioimage analysis organized within NEUBIAS – the Network of European Bioimage Analysts. This textbook is intended for advanced students in various fields of the life sciences and biomedicine, as well as staff scientists and faculty members who conduct regular quantitative analyses of microscopy images.
    Keywords: Analyzing Image Data in Biology ; Building a Bioimage Analysis Workflow ; Computational Analysis ; Chosing the Correct Components for Given Biological Questions ; Data Handling and Plotting ; Deep Learning ; Fast Computation ; GPU-Acceleration ; Handling Biological data ; Machine Learning ; Phyton ; Processing Language ; Understanding Bioimage Analysis Software ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Recombinant viruses expressing reporter fluorescent or bioluminescent proteins are an excellent option to evaluate the dynamics of viral infection progression in both cultured cells and/or validated animal models of viral infection. Reporter proteins are valid surrogates for direct detection of infected cells in vitro and in vivo, without the use of secondary methodologies to identify infected cells. By eliminating the need of secondary labeling, tractable replicating-competent, reporter-expressing viruses provide an ideal approach to monitor viral infections in real time, representing a significant advance in the study of the biology of viruses, to evaluate vaccination approaches, and to identify new therapeutics against viral infections using high-throughput screening settings. In this Special Issue “Replication-Competent Reporter-Expressing Viruses” we review replication-competent, reporter-expressing viruses belonging to different families, methods of characterization, and applications to facilitate the study of in vitro and in vivo viral infections. We also seek to discuss disadvantages and limitations associated with these reporter-expressing viruses. Finally, we provide rational future perspectives and additional avenues for the development, characterization, and applications of recombinant, reporter-expressing, competent viruses.
    Keywords: QH301-705.5 ; luminescence ; virus rescue approaches ; fluorescence ; Recombinant viruses ; plasmid-based reverse genetics ; reporter genes ; replicating-competent reporter-expressing viruses ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Introducing “A Feasible Approach for Natural Products to Treatment of Diseases”–an exploration of the therapeutic potential locked within nature’s abundant offerings. This comprehensive reprint delves into the fascinating realm of natural products, uncovering their inherent properties, mechanisms of action, and potential roles in effective disease management. Through extensive scientific research and reviews, the authors shed light on the immense potential of natural products as a viable approach to enhancing health and combating diseases. This reprint presents a diverse and multidimensional exploration, bridging the gap between traditional wisdom and contemporary scientific understanding and offering new avenues for healthcare professionals, researchers, and enthusiasts to harness the power of nature’s remarkable resources. As a catalyst for unlocking the healing potential of natural products, this reprint inspires further investigation and innovation, and drives us towards a future where their integration into mainstream healthcare becomes indispensable. Discover the possibilities and embark on a health and well-being journey with “A Feasible Approach for Natural Products to Treatment of Diseases”.
    Keywords: cancer immunotherapy ; fructan ; FT-IR ; mass spectrometry ; young green barley ; COVID-19 ; β-glucans ; immunomodulation ; anti-inflammation ; anti-oxidant ; ACE2 regulation ; impedance ; ECIS ; antitumor activity ; anticancer properties ; betulin ; betulinic acid ; Amadori rearrangement compounds ; barley ; anti-obesity ; arginyl-fructose ; adipogenic ; ergosta-5,7,22,24(28)-tetraenol (ERGT) ; cholesta-5,7,22,24-tetraenol (CHT) ; ergosterol biosynthesis ; antimetabolite ; suicide substrate ; Trypanosoma brucei ; coronavirus SARS-CoV-2 ; main protease ; Saussurea costus ; molecular docking ; GC-MS profiling ; Molineria recurvata ; diabetic nephropathy ; urinary biomarkers ; inflammation ; oxidative stress ; walnut ; Juglans regia ; high-fat diet ; insulin resistance ; cognitive function ; JNK/NFκB pathway ; Citri Reticulatae Pericarpium ; flavonoids ; anticancer ; mechanism ; phenotype ; Angelica sinensis polysaccharide ; Astragalus membranaceus polysaccharide ; hexokinase 2 ; glycolysis ; JAK2/STAT3 pathway ; liver regeneration ; Holoptelea integrifolia ; MMP-9 ; wound healing ; friedelin ; oxalactam A ; macrolactam ; anti-Rhizoctonia solani ; Penicillium oxalicum ; molecular dynamics ; non-alcoholic fatty liver disease (NAFLD) ; natural products ; terpenoids ; mechanisms ; treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 13
    Publication Date: 2024-04-02
    Description: California’s Juvenile Justice Crime Prevention Act provides funds for counties to offer evidence-based programs for high-need juvenile probationers and at-risk youth. This report, based on the annual report to the state legislature, outlines the program’s success for six outcome measures (completion of probation, restitution, and community service; arrests; probation violations; and incarcerations) and county-required supplemental outcomes.
    Keywords: Law ; History ; Political Science ; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::L Law::LN Laws of specific jurisdictions and specific areas of law::LNF Criminal law: procedure and offences::LNFQ Juvenile criminal law ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services::JKSW Emergency services::JKSW1 Police and security services ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKV Crime and criminology
    Language: English
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  • 14
    Publication Date: 2024-04-02
    Description: Drawing from 140 recently declassified documents, this report comprehensively examines the organization, territorial designs, management, personnel policies, and finances of the Islamic State of Iraq (ISI) and al-Qa‘ida in Iraq. Analysis of the Islamic State predecessor groups is more than a historical recounting. It provides significant understanding of how ISI evolved into the present-day Islamic State and how to combat the group.
    Keywords: Political Science ; History ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPW Political activism / Political engagement::JPWL Terrorism, armed struggle
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Keywords: QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 16
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    RAND Corporation
    Publication Date: 2024-03-29
    Description: On September 11, 2001, the United States was without a plan for military operations in Afghanistan. One was quickly created by the Defense Department and operations began October 7. The Taliban was toppled in less than two months. This report describes preparations at CENTCOM and elsewhere, Army operations and support activities, building a coalition, and civil-military operations in Afghanistan from October 2001 through June 2002.
    Keywords: History ; Political Science ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
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  • 17
    Publication Date: 2024-03-29
    Description: The composition of Air Force active and reserve forces is often contentious, especially during a force drawdown. This document seeks to inform force composition decisions by clarifying issues that affect the suitability of missions for assignment to the reserve components.
    Keywords: History ; Technology ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWC Military forces and sectors::JWCM Air forces and warfare ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Diet and nutrition are key tools in promoting health and reducing the comorbidities of chronic diseases. There are thousands of biomolecules in fruits, vegetables, wild and medicinal plants, other land and marine organisms, which can exert functional and health-promoting effects through bioactivity beyond nutrition. From the enormous amount of knowledge generated from different natural bioactive ingredients present in foods, we are aiming to bring together experts working in different fields of food, nutrition, and health, in order to work on this Special Issue, with a comprehensive collection of papers to gain insight into the most promising bioactive compounds in different foods, to improve the preservation of bioactivity during the food processing chain, and to provide scientific evidence of the efficacy of key bioactives in foods in preventing disease and improving health and wellbeing.
    Keywords: QH301-705.5 ; TX341-641 ; Health ; Bioactives ; Nutrition and Metabolism ; Nutrients ; Bioavailability ; Food ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The diversity of wood and non-wood forest products is enormous and reflected in their anatomical, physical and chemical properties as well as their potential applications. Special attention should be given to lesser-known species and even to invasive species, which may be profitable when properly managed, thereby decreasing the overexploitation of threatened species. Besides the market importance of stem wood, other tree components and non-wood forest products, often regarded simply as forest residual materials, are valuable forest resources with various potential applications that can strengthen the circular economy. Assessing the characteristics of these diverse materials, such as their structure and anatomy as well as their physical and chemical properties, is fundamental for evaluating their potential and increasing high-quality end-uses. This knowledge will also contribute to sustainable forest management with enhanced forest diversity and species conservation in addition to the reinforcement of certification and environmental policies.
    Keywords: Calamus zollingeri ; Calamus ornatus ; dynamic vapor sorption ; basic density ; volumetric swelling ; white rot ; mold ; Quercus suber L. ; seasonal variation ; cuticular waxes ; leaves ; new species ; morphology ; wood ; properties ; chemical composition ; spectroscopy ; chemometrics ; unconventional species ; Quercus suber ; cork borer ; cork ; phenolics ; tropical species ; wood anatomy ; wood density ; wood color ; multivariate analysis ; species diversity ; dark-brown zone ; lenticular filling tissue ; quantitative anatomical characteristics ; Quercus variabilis ; reproduction cork ; scanning electron microscopy ; sclereid ; virgin cork ; Cytisus scoparius ; liquefied ; optimization ; eco-valorization ; agro-industrial residues ; Asparagaceae ; lignocellulose ; crystalline cellulose ; syringyl/guaiacyl ; anatomy ; Tilia amurensis Rupr. ; Tilia mandshurica Rupr. & Maxim. ; branch ; wood properties ; papermaking material ; tropical timber ; color parameters ; mid-infrared spectroscopy ; FTIR ratios ; environmental factors ; West African Sahel ; Cupressus funebris Endl. wood ; wood knots ; physical properties ; wood color properties ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 21
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: New scientific advances in different areas have allowed the design of more precise strategies for the prevention and treatment of metabolic disorders through nutrition. In this context emerges the term Precision Nutrition, a new approach that takes advantage of scientific knowledge about the interaction of internal and external environmental factors to develop dynamic and precise nutritional recommendations. Therefore, Precision Nutrition includes personalized advice based on genetics and well-documented gene–nutrient–phenotype interactions, as well as other factors such as individual metabolome, transcriptome, and microbiota profile; food behavior; and dietary, physical activity, and life-style habits; and the resulting interactomes. Precision Nutrition should be based at least on three sequential steps: conventional nutritional approaches (considering age, gender, and physiological states); the incorporation of nutritional and health status information (e.g., metabolites, physical and nutritional behavior); and the genetic baggage including multiomics functional integration.
    Keywords: dietary parameters ; carbohydrate intake ; obesity ; single nucleotide polymorphism ; CLOCK gene ; rs3749474 ; sodium intake ; hypertension ; single-nucleotide polymorphism ; personalized nutrition ; dietary vitamin A ; body fat ; UCP ; retinoic acid ; PBMC ; genetic variant ; weight loss ; nutrigenomics ; dietary intervention ; FTO gene ; dietary protein ; dietary carbohydrates ; dietary fat ; macronutrients ; gene-diet interaction ; glucose homeostasis ; glaucoma ; polygenetic-risk scores ; gene-gene interaction ; gene-nutrient interaction ; precision medicine ; childhood ; insulin resistance ; adipokine ; metabolomics ; biomarkers ; ELOVL ; metabolic alterations ; Mexican population ; Single Nucleotide Polymorphisms ; pediatrics ; cardiometabolic risk factors ; precision nutrition ; eating behavior ; nutrigenetics ; microbiota ; metabolic syndrome ; Mediterranean diet ; genetic risk score ; HELENA ; adolescents ; sex ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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  • 22
    Publication Date: 2024-03-29
    Description: Freedom of movement (FoM) is the actual or perceived degree to which individuals or groups can move from place to place within a given environment or into and out of that environment. Focusing specifically on Afghanistan, this examination considers actual and perceived FoM for a range of groups and profiles the factors that influence them and affect data reporting in potentially misleading ways.
    Keywords: Political Science ; History ; Technology ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSH Espionage and secret services ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
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  • 23
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    RAND Corporation
    Publication Date: 2024-04-02
    Description: This book examines the strategic choices that American and Chinese decisionmakers face regarding sea power in the Western Pacific, shaped by geography, history, technology, and politics. In particular, the author explores the potential for cooperation on maritime security in the Western Pacific, and how the United States might pursue such cooperation as part of a broader strategy to advance its interests in the region.
    Keywords: History ; Political Science ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWC Military forces and sectors::JWCK Naval forces and warfare ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
    Language: English
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 25
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    RAND Corporation
    Publication Date: 2024-04-14
    Description: Current DoD force planning processes assume that U.S. military interventions are serially independent over time. This report challenges this assumption, arguing that interventions occur in temporally dependent clusters in which the likelihood of an intervention depends on interventions in the recent past. Integrating the concept of temporal dependence into DoD planning processes could help planners develop more appropriate force estimates.
    Keywords: History ; Statistics ; Technology ; thema EDItEUR::U Computing and Information Technology::UN Databases::UNA Database design and theory ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBT Probability and statistics
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  • 26
    Publication Date: 2024-04-05
    Description: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 27
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The intention of this Special Issue is to focus on new aspects of drug discovery, including the search for new molecular targets of various diseases, the creation of new modern methods for diagnosing diseases, the development of new test systems and kits for assessing the selectivity and effectiveness of new drugs, the study of the molecular mechanisms of biologically active compounds, the formulation of new drugs, pharmacokinetic and pharmacodynamic studies, and preclinical trials of important molecules.
    Keywords: Streptococci ; antimicrobials ; QSAR ; MD simulation ; Kunitz-type peptides ; neuroprotective activity ; sea anemones ; TRPV1 ; P2X7R ; Parkinson’s disease (PD) ; diffuse large B cell lymphoma (DLBCL) ; deep neural network ; drug discovery ; drug combination ; biomarker ; cancer severity ; cancer prognosis ; MAFB ; tumor-associated macrophages ; prostate cancer ; photodynamic therapy ; magnetic resonance imaging ; ex vivo ; anti-inflammatory substance ; N-acylhydrazone ; naphthyl-N-acylhydrazone ; LASSBio-1524 analogues ; phosphacoumarin ; azomethine ylide ; cycloaddition ; anti-cancer ; cytotoxicity ; quantum chemistry ; pravastatin ; metformin ; radiation-induced intestinal injury ; minipigs ; epithelial regeneration ; inflammation ; arylazo sulfones ; DNA binding ; DNA cleavage ; DNA photocleavage ; A375 melanoma cells ; molecular docking ; radicals ; N–S bond homolysis ; platinum(II) ; five-coordinate complexes ; glycoconjugation ; cytotoxic activity ; protein X-ray structure ; lipophilicity ; natural products ; acetylcholinesterase inhibitors ; butyrylcholinesterase inhibitors ; Alzheimer’s disease ; central nervous system ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 28
    Publication Date: 2023-10-05
    Description: Congress enacted the Terrorism Risk Insurance Act (TRIA) in 2002, in response to terrorism insurance becoming unavailable or extremely costly in the wake of the 9/11 attacks. TRIA is set to expire at the end of 2014, and Congress is considering the appropriate government role in terrorism insurance markets. This policy brief examines the potential national security implications of allowing TRIA to expire.
    Keywords: Political Science ; History ; Business ; bic Book Industry Communication::K Economics, finance, business & management::KF Finance & accounting::KFF Finance::KFFN Insurance & actuarial studies ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPW Political activism::JPWL Terrorism, armed struggle
    Language: English
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  • 29
    Publication Date: 2024-03-29
    Description: RAND supported the Kurdistan Regional Government in its aims to restructure its Ministry of Education, develop a plan for a school quality assurance system, review effectiveness of monitoring and support of private schools, and assess the quality of in-service teacher training. RAND researchers conducted interviews, reviewed literature, examined case studies in other countries, provided analysis, and developed implementation guidelines.
    Keywords: Education ; History ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNF Educational strategies & policy ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education::JNMT Teacher training ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJF Asian history::HBJF1 Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JN Education::JNK Educational administration and organization ; thema EDItEUR::J Society and Social Sciences::JN Education::JNF Educational strategies and policy ; thema EDItEUR::J Society and Social Sciences::JN Education::JNM Higher education, tertiary education::JNMT Teacher training ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history
    Language: English
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  • 30
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The range of human neurodegenerative diseases continues to pose significant unmet medical needs for societies around the world. The progressive and terminal nature of these conditions places a considerable personal burden on the individual affected but also on public health systems and health services. Tens of millions of people are indiscriminately affected by various dementias, which are rising at an alarming rate. There are no cures for many conditions, and it is clear that treatments applied as early as possible could greatly improve outcomes for patients. Therefore, new disease classification and diagnostic tools should be a key priority. Metabolomics represents a relatively new field of analytical science, which can be extremely useful in the early diagnosis of disease. The relatively unique feature of metabolites is that they sit at the intersection between the genetic background of an organism and its environment. Because many neurodegenerative diseases are not genetically inherited (instead having a range of known genetic risk factors and also a large number of unknown environmental triggers) the field of metabolomics offers great promise for the discovery of new, biologically, and clinically relevant biomarkers for neurodegenerative disorders. It is already bringing forward new knowledge in terms of the mechanisms of neurodegenerative disease.
    Keywords: QH301-705.5 ; Q1-390 ; glutamic acid ; n/a ; direct mass spectrometry ; neurodegeneration ; 6-OHDA ; targeted mass spectrometry ; mitochondrial dysfunction ; myo-inositol ; metabolomics ; bile acids ; subacute mild traumatic brain injury ; age-related macular degeneration ; metabolic pathways ; energy metabolism ; midbrain ; Alzheimer’s disease ; biomarkers ; 1H NMR ; Parkinson’s disease dementia ; GC-MS ; pathogenesis ; tricarboxylic acid cycle ; micro-dialysis ; 13C-labeled succinate ; metabolism ; lipidomics ; dementia with Lewy bodies ; fatty acid ; prodromal Parkinson’s disease ; malonate ; cerebral ischemia ; mass spectrometry ; retinal pigment epithelium ; excitotoxicity ; endothelin-1 ; reperfusion ; C. elegans ; Streptomyces venezuelae ; ?-synuclein aggregates ; natural product ; fatty acid metabolism ; imaging mass spectrometry ; LC-MS ; drusen ; cerebral palsy ; plasma ; Parkinson’s disease ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 31
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Welfare is a multidimensional concept that can be described as the state of an animal as it copes with the environment. Captive environments can impact farmed animals at different levels, especially fishes, considering their highly complex sensory world. Understanding the ethology of a species is therefore essential to address fish welfare, and the interpretation of behavioral responses in specific rearing contexts (aquaculture or experimental contexts) demands knowledge of their underlying physiological, developmental, functional, and evolutionary mechanisms. In natural environments, the stress response has evolved to help animals survive challenging conditions. However, animals are adapted to deal with natural stressors, while anthropogenic stimuli may represent stressors that fishes are unable to cope with. Under such circumstances, stress responses may be maladaptive and cause severe damage to the animal. As welfare in captivity is affected in multiple dimensions, multiple possible indicators can be used to assess the welfare state of individuals. In the past, research on welfare has been largely focusing on health indicators and predominantly based on physiological stress. Ethological indicators, however, also integrate the mental perspective of the individual and have been gradually assuming an important role in welfare research: behavioral responses to stressors are an early response to adverse conditions, easily observable, and demonstrative of emotional states. Many behavioral indicators can be used as non-invasive measurements of welfare in practical contexts such as aquaculture and experimentation. Presently, research in fish welfare is growing in importance and interest because of the growing economic importance of fish farming, the comparative biology opportunities that experimental fishes provide, and the increasing public sensitivity to welfare issues.
    Keywords: QH301-705.5 ; SF1-1100 ; Q1-390 ; n/a ; muscle texture ; fractal analysis ; fish welfare ; Danio rerio ; motivation ; histopathology ; elevated phosphate concentrations ; sharks ; welfare ; African catfish (Clarias gariepinus) ; feed efficiency ; fighting ability ; aggressive interaction ; social rank ; boldness ; ethology ; fisheries management ; physiological response ; FishEthoBase ; welfare scores ; welfare criteria ; stress ; pain ; stereotypical behaviour ; Scyliorhinus canicula ; animal behavior ; welfare enhancement ; social communication ; nociception ; negative and positive affect ; aggression ; fertilisation success ; risk analysis ; aquaculture ; hematology ; Amyloodinium ocellatum ; framework ; structural complexity ; territorial ; growth ; positive welfare ; social stress ; age ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 32
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The re-use of industrial food residues is essential in the general framework of rational waste handling and recycling, which aims at the minimizing environmental impact of food production and producing functional food ingredients. Agri-food processing waste has long been considered a valuable biomass with a significant polyphenol load and profile. Polyphenols, aside from being powerful antioxidants that confer inherent stability to a variety of foods, may possess versatile bioactivities including anti-inflammatory and chemopreventive properties. The valorization of agri-food waste as a prominent source of polyphenols stems from the enormous amount of food-related material discharged worldwide and the emerging eco-friendly technologies that allow high recovery, recycling, and sustainable use of these materials. This book addresses the concept of recovering natural polyphenolic antioxidants from waste biomass generated by agri-food and related industrial processes and presents state-of-the-art applications with prospect in the food, cosmetic, and pharmaceutical industries.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; polyphenols ; n/a ; valorization ; ultrasound assisted extraction ; microwave assisted extraction ; Box–Behnken design ; HPLC-DAD-q-TOF-MS ; Dioscorea batatas ; green oleo-extraction ; grape marc ; quantitative analysis ; natural antioxidants and flavors ; antioxidant ; infrared-assisted extraction ; anti-ageing ; anthocyanins ; liquid chromatography-mass spectrometry ; Chinese yam ; functional food ; extraction ; olive mill wastewater ; adsorbents ; relative solubility simulation ; HPLC-fluorometric detector (FLD)–MS ; saffron ; antioxidants ; food-grade solvents ; Mango ; zero-waste biorefinery ; response surface methodology ; ophthalmic hydrogel ; olive leaves ; sonotrode ultrasonic-assisted extraction ; vegetable oils and derivatives ; anti-inflammatory ; skin whitening ; phenolics ; Brewers’ spent grains ; proanthocyanidins ; brewer’s spent grain ; anti-inflammatory and antioxidant activity ; antimicrobial activity ; by-products ; antiplatelet activity ; phenanthrenes ; wine lees ; bioactive compounds ; deep eutectic solvents ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 33
    Publication Date: 2024-04-14
    Description: This study for the U.S. Marine Corps presents a historical overview of the integration of women into the U.S. military and explores the importance of cohesion and what influences it. The gender integration experiences of foreign militaries, as well as the gender integration efforts of domestic police and fire departments, are analyzed for insights into effective policies. The potential costs of integration are analyzed as well.
    Keywords: Management & Organizational Behavior ; History ; Business ; thema EDItEUR::V Health, Relationships and Personal development::VS Self-help, personal development and practical advice::VSC Advice on careers and achieving success ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas::KJMV2 Personnel and human resources management ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy
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  • 34
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Mycotoxins are secondary metabolites produced by molds. Although the primary role of these toxins is thought to be related to the colonisation of the environment by the fungi—mycotoxins are able to kill other micro-organisms (antimicrobial effect) and/or plant cells (mycotoxin-producing fungi being necrophagic)—the exposure of animals and humans to mycotoxins through the consumption of mycotoxin-contaminated food and feeds leads to diseases and death. Among the different mycotoxins described (more than 350 mycotoxins have been identified), deoxynivalenol (DON or vomitoxin) produced by Fusarium species has attracted the most attention due to its prevalence and toxicity. DON is part of a family of mycotoxins called trichothecenes that are small sesquiterpenoids with an epoxide group at positions 12–13 allowing their binding to ribosomes causing the so-called ribosome stress response, characterized by the activation of various protein kinases that lead to alterations in gene expression and cellular toxicity in animals, humans and plants. Here, we compiled very recent findings regarding DON and its derivatives: i) their prevalence in human food; ii) the estimation of the exposure of humans to them using biological markers; iii) their roles during plant–fungi interaction; iv) the alteration caused by them in animals and humans, particularly at low doses that are close to those observed in farm animals and human consumers; v) possible strategies to decrease their presence in food and feeds. Overall, this book will give the reader a clear and global view on this important mycotoxin produced by Fusarium species which is responsible for huge economic loss and health issues.
    Keywords: QH301-705.5 ; cell entry ; deoxynivalenol ; DON derivative ; cell effect ; trichothecene ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 35
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This Urological Cancer 2020 collection contains a set of multidisciplinary contributions to the extraordinary heterogeneity of tumor mechanisms, diagnostic approaches, and therapies of the renal, urinary tract, and prostate cancers, with the intention of offering to interested readers a representative snapshot of the status of urological research.
    Keywords: renal cell carcinoma ; iron ; macrophages ; chelation therapy ; urothelial carcinoma ; transcriptome ; microtubule ; MAP1B ; prognosis ; KLF5 ; androgen receptor ; cell proliferation ; tumorigenesis ; prostate cancer ; precision medicine ; whole genome sequencing ; optical mapping ; therapy ; prostate carcinoma ; prostate mpMRI ; machine learning ; artificial intelligence ; deep learning ; neural network ; angiogenesis ; angiogenic growth factors ; antiangiogenic therapy ; renal tumors ; prevention ; α1-adrenoceptor antagonists ; anoikis ; vascularity ; research model ; oncogenes ; tumor suppressor genes ; MR-guided ; radiotherapy ; MRgRT ; stereotactic ablative radiotherapy ; stereotactic ablative radiation therapy (SABR) ; renal cell cancer ; RCC ; online adaptive ; [68Ga]Ga-PSMA PET/CT ; dual-time point imaging ; delayed imaging ; biphasic imaging ; lesion positivity rate ; CXCL9 ; PD1 ; PD-L1 ; stage T1 NMIBC ; prostatic neoplasms/mortality ; prostatic neoplasms/epidemiology ; SEER Program ; bladder cancer ; transurethral resection ; en-bloc resection ; CPT1A ; fatty acids ; serine ; androgen response ; ROS ; oxidative stress ; DONSON ; Downstream Neighbor of SON ; biomarker ; metastatic spread ; diagnosis ; differential diagnosis ; histopathology ; immunohistochemistry ; stroma signature ; patient-derived xenografts ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 36
    Publication Date: 2024-04-02
    Description: Gastroenterology and cardiology services are common and costly among Medicare beneficiaries. Episode-based payment models may offer a way to create incentives for high-quality, low-cost care. This report describes research related to the design of episode-based payment models for ambulatory gastroenterology and cardiology services for possible testing by the Centers for Medicare and Medicaid Services’ Center for Medicare and Medicaid Innovation.
    Keywords: Health Sciences ; History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBP Health systems and services::MBPR Medical insurance
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  • 37
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Concerns have been raised with respect to the state of high-altitude and high-latitude treelines, as they are anticipated to undergo considerable modifications due to global changes, and especially due to climate warming. As high-elevation treelines are temperature-limited vegetation boundaries, they are considered to be sensitive to climate warming. As a consequence, in this future, warmer environment, an upward migration of treelines is expected because low air and root-zone temperatures constrain their regeneration and growth. Despite the ubiquity of climate warming, treeline advancement is not a worldwide phenomenon: some treelines have been advancing rapidly, others have responded sluggishly or have remained stable. This variation in responses is attributed to the potential interaction of a continuum of site-related factors that may lead to the occurrence of locally conditioned temperature patterns. Competition amongst species and below-ground resources have been suggested as additional factors explaining the variability in the movement of treelines. This Special Issue (book) is dedicated to the discussion of treeline responses to changing environmental conditions in different areas around the globe.
    Keywords: QH301-705.5 ; QK1-989 ; Q1-390 ; n/a ; tree seedling recruitment ; shrubline ; light quality ; higher altitude ; precipitation ; experimental rain exclusion ; Pinus cembra ; Changbai Mountain ; treeline dynamics ; fungal ecology ; thermal continentality ; tree regeneration ; elevational transect ; monitoring ; conifer shrub ; plant water availability ; permafrost ; foehn winds ; treeline ; Holocene ; nitrogen cycling ; carotenoids ; timberline ; 15N natural abundance ; spectrometer ; basal area increment ; palynology ; xylem embolism ; diversity ; elevational treeline ; European Alps ; temperature ; tree line ; winter stress ; photosynthetic pigments ; Pinus sibirica ; westerly winds ; relative air humidity ; ecosystem manipulation ; Larix decidua ; microsite ; polar treeline ; Central Austrian Alps ; Switzerland ; multi-stemmed growth form ; conifers ; forest edge ; history of treeline research ; soil drought ; dendroclimatology ; knowledge engineering ; Rocky Mountains ; apical control ; cloud ; postglacial ; alpine timberline ; space-for-time substitution ; climate change ; expert elicitation ; shoot elongation ; pit aspiration ; climate warming ; climate zone ; alpine treeline ; refilling ; Abies sibirica ; growth trend ; western Montana ; light quantity ; Picea abies ; Mediterranean climate ; forest climatology ; altitude ; environmental stress ; sub-Antarctic ; Erman’s birch ; photoinhibition ; tocopherol ; elevational gradients ; NDVI ; long-term trends ; sap flow ; peat ; tree seedlings ; Southern Ocean ; chlorophyll ; non-structural carbohydrates (NSCs) ; drought ; upward advance ; remote sensing data ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 38
    Publication Date: 2023-10-05
    Description: This executive summary describes key results from four studies carried out by the RAND Corporation in Phase II of its work for the Kurdistan Regional Government (KRG). RAND’s work aims to help the KRG expand access to high-quality technical and vocational education and training; improve access to, the quality of, and financing for health care; improve the private sector labor market; and prepare and conduct the Kurdistan Region Labor Force Survey.
    Keywords: History ; Business ; Health Sciences ; Management & Organizational Behavior ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCF Labour economics ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJF Asian history::HBJF1 Middle Eastern history ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBQ Medicolegal issues
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  • 39
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Forests cover 30% of the Earth’s land area, or nearly four billion hectares. Enhancing the benefits and ecosystem services of forests has been increasingly recognized as an essential part of nature-based solutions for solving many emerging global environmental problems today. A core science supporting forest management is understanding the interactions of forests, water, and people. These interactions have become increasingly complex under climate change and its associated impacts, such as the increases in the intensity and frequency of drought and floods, increasing population and deforestation, and a rise in global demands for multiple ecosystem services including clean water supply and carbon sequestration. Forest watershed managers have recognized that water management is an essential component of forest management. Global environmental change is posing more challenges for managing forests and water toward sustainable development. New science on forest and water is critically needed across the globe. The International Forests and Water Conference 2018, Valdivia, Chile (http://forestsandwater2018.cl/), a joint effort of the 5th IUFRO International Conference on Forests and Water in a Changing Environment and the Second Latin American Conference on Forests and Water provided a unique forum to examine forest and water issues in Latin America under a global context. This book represents a collection of some of the peer-reviewed papers presented at the conference that were published in a Special Issue of Forests.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; social capital ; Cambodia ; forest and water policy ; land use and land cover change ; shrubland ; “Forests to Faucets” ; precipitation gradient ; forest ecosystem management ; afforestation ; connectivity ; land use change ; forest operations ; Chile ; catchment management ; forest plantation ; climate change ; compound wildfire-water risk ; native forest ; hydrology ; wetland ; streamside native buffer ; sustainability ; participatory monitoring ; hydrological modeling ; timber harvesting ; water quality ; native forests ; source water protection ; global change ; forest hydrology ; community drinking-water ; SDGs ; drinking-water security ; Oregon ; forest ; aquatic-riparian ecosystems ; NDC ; heat: moisture index ; watershed management ; load ; Rhyacotriton ; ecohydrology ; nutrient concentrations ; multi-criteria analysis ; Loess Plateau ; dissolved organic matter ; US Pacific Northwest ; soil moisture ; agricultural lands ; water management ; water provision ; water supply ; forests ; post-fire hydrology ; grassland ; forest plantations ; restoration strategy ; riparian buffer zones ; Mekong ; riparian vegetation ; density management harvest ; SWAT model ; forest watersheds ; water governance ; Nenjiang River ; forestry ; ecosystem services ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 40
    Publication Date: 2024-04-14
    Description: The Wounded Warrior Project has developed programs to help care for injured service members and veterans. This report describes how project alumnus respondents are faring in domains related to mental health and resiliency, physical health, and employment and finances.
    Keywords: History ; Law ; Public Health ; thema EDItEUR::V Health, Relationships and Personal development::VF Family and health::VFD Popular medicine and health ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWX Other warfare and defence issues::JWXV Military veterans ; thema EDItEUR::L Law::LN Laws of specific jurisdictions and specific areas of law::LNH Employment and labour law: general
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  • 41
    Publication Date: 2023-10-05
    Description: This report examines mechanisms, sources, and inter-Service agreements for funding special operations forces (SOF) operations and provides recommendations to reduce the frequency and duration of disputes between the United States Special Operations Command, the Military Departments, and Geographic Combatant Commands over their respective funding responsibilities for SOF.
    Keywords: History ; Finance ; bic Book Industry Communication::K Economics, finance, business & management::KF Finance & accounting::KFF Finance ; bic Book Industry Communication::H Humanities::HB History::HBW Military history ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWK Defence strategy, planning & research
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  • 42
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics.
    Keywords: QH301-705.5 ; Q1-390 ; thermodynamic modeling ; molecular dynamics simulation ; poorly soluble drugs ; amorphous solid dispersions ; dissolution enhancement ; crystallization tendency ; continuous processing ; stability ; milling ; granulation ; thermal analysis ; amorphous ; ball milling ; pharmaceutical glass ; dissolution ; rebamipide ; poloxamer ; classification ; polyelectrolytes ; amorphisation ; self-assembly ; dissolution rate ; miscibility ; bioavailability ; solubility ; evaporation ; mesoporous ; polyelectrolyte excipient matrix ; polymer ; bicaludamide ; phase diagram ; Weibull dissolution model ; spectroscopic techniques ; anticancer drugs ; manufacturing methods ; nucleation ; molecular complex ; nanoaggregates ; enrofloxacin ; accelerated stability test ; solubility enhancement ; amorphous solid dispersion ; tadalafil ; process development ; amorphous polymeric salt ; Wood’s apparatus ; hot melt extrusion ; solid dispersions ; intrinsic dissolution rate ; solid dispersion ; interaction ; crystallization ; spray drying ; characterization ; ciprofloxacin ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 43
    Publication Date: 2024-03-29
    Description: In the 2010–2011 school year, two educational programs launched in New Haven, Connecticut: New Haven School Change, a sweeping K–12 educational reform to improve the learning of educational outcomes of its students, and New Haven Promise, a scholarship program intended to improve college-going culture and encourage graduates to attend college. This report documents a study of early progress in these programs.
    Keywords: Education ; History ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNL Schools::JNLC Secondary schools ; bic Book Industry Communication::J Society & social sciences::JN Education::JNS Teaching of specific groups & persons with special educational needs::JNSV Teaching of students with English as a second language (TESOL) ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JN Education::JNM Higher education, tertiary education ; thema EDItEUR::J Society and Social Sciences::JN Education::JNL Schools and pre-schools::JNLC Secondary schools ; thema EDItEUR::J Society and Social Sciences::JN Education::JNU Teaching of a specific subject ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
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  • 44
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Rivers have been intensively degraded due to increasing anthropogenic impacts from a growing population in a continuously developing world. Accordingly, most rivers suffer from pressures as a result of increasing dam and weir construction, habitat degradation, flow regulation, water pollution/abstraction, and the spread of invasive species. Science-based knowledge regarding solutions to counteract the effects of river degradation, and melding principles of aquatic ecology and engineering hydraulics, is thus urgently needed to guide present and future river restoration actions. This Special Issue gathers a coherent set of studies from different geographic contexts, on fundamental and applied research regarding the integration of ecohydraulics in river restoration, ranging from field studies to laboratory experiments that can be applied to real-world challenges. It contains 13 original papers covering ecohydraulic issues such as river restoration technologies, sustainable hydropower, fish passage designs and operational criteria, and habitat modeling. All papers were reviewed by international experts in ecology, hydraulics, aquatic biology, engineering, geomorphology, and hydrology. The papers herein well represent the wide applicability of ecohydraulics in river restoration and serve as a basis to improve current knowledge and management and to reduce arguments between different interests and opinions.
    Keywords: QH301-705.5 ; Q1-390 ; Fish passage and migration ; Prioritization of river connectivity for sustainable fisheries ; Sustainable hydropower ; Spawning grounds ; Invasive species management ; Environmental flows ; Habitat modeling ; Dam/weir retrofitting and removal ; Riparian and aquatic vegetation dynamics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 45
    Publication Date: 2024-04-02
    Description: Since the 2011 revolution in Egypt, the Muslim Brotherhood has emerged as a key political player. Although individuals under the age of 35 make up a large share of the membership, the group’s strict hierarchy has led to disaffection among its youth. These members merit attention not only as a challenge to the Brotherhood’s organizational cohesion, but as a potential conduit for expanding U.S. engagement with the group.
    Keywords: History ; Political Science ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
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  • 46
    Publication Date: 2023-10-05
    Description: Over the past decade, the government has expanded funding and services to meet increasing demand for improved veteran access to high-quality mental health services. This report describes findings from a study designed to gather information on mental health–related needs facing veterans in the Detroit metropolitan area to identify gaps in the support landscape and inform future investments for community-level resources to fill the identified gaps.
    Keywords: Health Sciences ; Management & Organizational Behavior ; History ; Psychology ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWX Other warfare & defence issues::JWXV Military veterans ; bic Book Industry Communication::M Medicine::MQ Nursing & ancillary services ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBQ Medicolegal issues ; bic Book Industry Communication::J Society & social sciences::JM Psychology::JMP Abnormal psychology
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  • 47
    Publication Date: 2024-04-02
    Description: This report outlines choices, options and trade-offs to policymakers, programme operators and researchers interested in the evaluation of chronic disease management. It is based on analyses undertaken within the DISMEVAL project.
    Keywords: Health Sciences ; History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBG Medical equipment and techniques::MBGR Medical research
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  • 48
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.
    Keywords: QH301-705.5 ; genome stability ; Trisomies ; microtubule dynamics ; Checkpoints ; Inheritance ; Cell division ; centrosome ; Down Syndrome ; Cell motility ; Cell regulation ; chromosome segregation ; Microtubules ; Cell cycle ; kinetochore ; Cytoskeleton ; Cell reproduction ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 49
    Publication Date: 2023-10-05
    Description: This report documents key technological innovations in the energy sector; identifies best practices of educational and training programs that have successfully responded to evolving labor markets in other sectors; analyzes four case-study energy-sector education and training programs in southwestern Pennsylvania; and provides recommendations for the energy-sector education and training system in the region.
    Keywords: Physics ; History ; Education ; Business ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHD Classical mechanics::PHDY Energy
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  • 50
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Dear Colleagues, When Hayflick and Moorhead coined the term “cellular senescence” (CS) almost 60 years ago, this phenomenon was understood as a mechanism, usually induced by activation of the DNA-repair machinery, to prevent uncontrolled proliferation. Meanwhile, additional beneficial roles for CS have been identified, such as embryonic development and wound healing. The senescence associated secretory phenotype (SASP) activated in most senescent cells (SC) signals to the immune system “come here and remove me”. In organisms with young and functional immune systems, occurring SC are usually detected and removed. If SC remain in the tissue expressing the SASP, this will cause not just a damaging local inflammation but can also induce remodeling and regeneration of the surrounding tissue as well as spreading of senescence. Old organisms show reduced regenerative potential and immune function which leads to accumulation of SC. Accordingly, accumulation of SC was observed in tissues of aged individuals, but importantly also in the context of age-related disorders, neurodegenerative, or cardiovascular diseases and others. Because of its detrimental effect of the surrounding tissue, accumulation of SC is not just a consequence, but can rather been understood as a major driver of aging. In line with this, recent studies described that removal of SC showed beneficial effects on healthspan and lifespan. This exciting research led to the discovery of “senolytics”, drugs which can kill SC. Given the heterogeneity of cell types that show senescence-like phenotypes, including heart muscle and post-mitotic neuronal cells, further research is required to unravel the molecular background that renders a cell type vulnerable to senesce. Additionally, it will be important to understand how senescence is cell type-specifically induced and which molecules serve as drug targets to prevent senescence and its spreading, or actively kill SC. This special issue will shed light on the molecular pathways of CS and inflammaging and on possible strategies to interfere with these processes. Dr. Markus Riessland Guest Editor
    Keywords: γH2AX ; Alzheimer’s disease ; DNA damage ; mild cognitive impairment ; senescence ; secreted protein acidic and rich in cysteine ; regeneration ; homeostasis ; cellular senescence ; biology of aging ; neurodegeneration ; brain ; geroscience ; senolytics ; tauopathy ; cancer ; stress response ; post-mitotic ; neuronal senescence ; amyotrophic lateral sclerosis ; senescence-associated secretory phenotype (SASP) ; cell-cycle ; melanoma ; pancreatic adenocarcinoma ; tumor infiltration ; chemotherapy resistance ; prostate ; inflammation ; AIM2 inflammasome ; POP3 ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 51
    Publication Date: 2023-10-05
    Description: The Joint Improvised Explosive Device Defeat Organization (JIEDDO) carries out training activities both as part of its equipment and system development responsibilities and its responsibility to “train the force” in IED threats and countermeasures. This report assesses whether JIEDDO’s programs and functions may be duplicative with those of the military Services, U.S. Special Operations Command, and other agencies.
    Keywords: History ; Business ; Technology ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWM Weapons & equipment ; bic Book Industry Communication::H Humanities::HB History::HBW Military history ; bic Book Industry Communication::T Technology, engineering, agriculture::TT Other technologies & applied sciences::TTM Military engineering
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  • 52
    Publication Date: 2024-04-02
    Description: India’s core goals for Southeast Asia are in basic harmony with those of the United States, including regional stability, peaceful settlement of territorial disputes, and containment of radicalism Still, America should not expect India to enter any sort of alliance, nor join any coalition to balance against China, but should demonstrate strategic patience and willingness to cultivate a long-term relationship.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
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  • 53
    Publication Date: 2024-04-05
    Description: Ranaviruses and other viruses within the family Iridoviridae, infect a wide range of ecologically and commercially important ectothermic vertebrates, i.e., bony fish, amphibians, and reptiles, and invertebrates, including agricultural and medical pests and cultured shrimp and crayfish, and are responsible for considerable morbidity and mortality. Understanding the impact of these various agents on diverse host species requires the combined efforts of ecologists, veterinarians, pathologists, comparative immunologists and molecular virologists. Unfortunately, investigators involved in these studies often work in discipline-specific silos that preclude interaction with others whose insights and approaches are required to comprehensively address problems related to ranavirus/iridovirus disease. Our intent here is to breakdown these silos and provide a forum where diverse researchers with a common interest in ranavirus/iridovirus biology can profitably interact. As a colleague once quipped, “Three people make a genius.” We are hoping to do something along those lines by presenting a collection of research articles dealing with issues of anti-viral immunity, identification of a potentially novel viral genus exemplified by erythrocytic necrosis virus, viral inhibition of innate immunity, identification of novel hosts for lymphocystivirus and invertebrate iridoviruses, and modelling studies of ranavirus transmission. Collectively these and others will exemplify the breadth of ongoing studies focused on this virus family.
    Keywords: QH301-705.5 ; Q1-390 ; risk assessment ; n/a ; CQIV ; mathematical models ; amphibian ; iridovirus ; ISDL ; Exopalaemon carinicauda ; viral load ; virus isolation ; European chub ; outbreak ; Unconventional T cell ; early detection ; susceptible species ; viral immune evasion ; DNA virus ; Rana grylio virus ; antibody ; intracellular localization ; Rana grylio virus (RGV) ; British Columbia ; Iridoviridae ; Andrias davidianus ranavirus ; viral infection ; susceptible-infected (SI) models ; yeast two-hybrid (Y2H) ; prevalence ; host-pathogen interactions ; Pacific herring ; Procambarus clarkii ; Bayesian inference ; eDNA ; amphibians ; Artemia spp. ; ranavirosis ; cross-species transmission ; FV3 ; SHIV ; Gryllus bimaculatus ; Pacific salmon ; NF-?B ; cricket ; IIV-6 ; virus binding ; erythrocytic necrosis virus (ENV) ; envelope protein ; iridovirus core proteins ; emerging infection ; host ; Ranavirus ; white head ; Rana temporaria ; Imd ; biosecurity ; antiviral immunity ; Decapodiridovirus ; endemic disease ; Macrobrachium rosenbergii ; co-immunoprecipitation (Co-IP) ; Common frog ; aquatic animals ; virus surveillance ; immunomodulators ; frog virus 3 ; ELISA ; DIV1 ; megalocytivirus ; Lymphocystis disease virus ; bearded dragon ; susceptibility ; protein interaction ; Pogona vitticeps ; viral erythrocytic necrosis (VEN) ; histopathology ; epidemiology ; native-fish conservation ; viral transmission ; Sparus aurata ; immunohistochemistry ; lizard ; disease dynamics ; immunofluorescence ; transmission modelling ; Macrobrachium nipponense ; interferon ; nonclassical MHC ; heparan sulfate ; ranavirus ; Mexico ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 54
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    RAND Corporation
    Publication Date: 2024-04-02
    Description: In the past two decades, the U.S. Air Force has participated in three contingencies involving no-fly zones (NFZs) over Bosnia, Iraq, and Libya, and NFZ proposals have been proffered for some time as an option for intervention in the Syrian civil war that would avoid placing Western troops on the ground. This paper is intended as a preliminary look at NFZs as a strategic approach in such situations, with an emphasis on the forms they might take, their potential utility, and their probable limitations.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWC Military forces and sectors::JWCM Air forces and warfare
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  • 55
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: In the past 20 years, karst desertification control has produced remarkable results, and the South China karst has been a global hotspot for greening. However, in the new stage of karst desertification control, the functional lag of forest ecosystems and the insufficient supply capacity of ecosystem services are gradually becoming prominent. We not only lack systematic research on vulnerability and resilience, structure and stability, ecological assets and services, carrying capacity and ecological security, and service trade-offs/synergies and optimization in controlled ecosystems. There is still a lack of research on the ecological processes of newly constructed forests in improving ecosystem functions and services. Therefore, this reprint mainly focuses on the research improvement of forest ecosystem functions in karst desertification control. This includes the improvement mechanism of ecosystem structure, function, and services, the mechanism of ecosystem service tradeoff/synergy, and function optimization. An optimization model of ecosystem function and an improvement path for eco-product supply are introduced. The role of functional traits in the maintenance of ecological function and services is also established, and social–ecological responses to afforestation in karst desertification control are discussed.
    Keywords: structural trait ; element trait ; physiological trait ; leaf ; root ; karst ; ecosystem service supply ; value accounting ; eco-industry ; karst desertification environment ; farmland hydrological cycle ; agroforestry ; agronomic measures to water saving ; planting combinations ; investment strategy ; plant adaptability ; soil ; response ; biodiversity ; ecosystem services ; forests ; karst desertification ; plant functional traits ; structure ; landscape security pattern ; sensitivity ; landscape connectivity ; Guanling County ; Guizhou ; ecological products ; value realization ; ecological industry ; resilient landscape ; rural planning ; resilience assessment ; karst rocky desertification control areas ; karst forest ; vegetation water use strategy ; hydrogen and oxygen stable isotopes ; hydrologic niche separation ; principal component analysis ; redundancy analysis ; karst rocky desertification area ; species diversity ; evaluation indicator systems ; fuzzy integrated evaluation ; karst spring ; dissolved organic carbon/nitrogen ; rocky desertification ; terrestrial ecosystem ; soil aggregate stability ; soil nutrients ; vegetation restoration ; karst rocky desertification ; forest ; karst desertification control ; loquat ; intercropping peanut ; N2O emission ; Abies fanjingshanensis ; microbial carbon use efficiency ; physicochemical indices ; bacteria ; fungus ; structural optimization ; water and fertilizer regulation ; functional improvement ; forests ecosystem ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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  • 56
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: It is currently apparent that extracellular ATP's physiological effect is mediated by its interaction with specific purinergic receptors. All purinergic receptors are divided into P1-purinoreceptors and P2-purinoreceptors. Each of the subtypes is divided into a number of families. For instance, P2 receptors are divided into P2X and P2Y receptors according to the mechanism by which their effect is realized: P2Y are G-protein-coupled receptors, while P2X receptors are ligand-operated ion channels. P2X receptors are important molecular therapeutic targets, the malfunctioning of which leads to severe complications in the physiology of humans and animals and causes dangerous diseases. The search for compounds that can modulate the function of purinergic receptors can lead to the creation of new drugs that are effective in central and peripheral nervous system and immune system disease treatment, including neuroinflammation, hypoxia/ischemia, epilepsy and neuropathic pain. In this Special Issue, we wish to offer a platform for high-quality publications on the latest advances in the identification of P2X/Y- and P1-receptor blockers, functions and regulation by them; the characterization of these receptor signaling networks and crosstalk; mechanisms underlying the role of purinoceptors in neurodegenerative illnesses as well as chronic neuronal changes following acute noxious damage and therapeutic opportunities associated with regulation of purinergic receptor activity.
    Keywords: adenosine receptors ; adipogenesis ; osteogenesis ; adipose tissue ; bone marrow ; obesity ; neonatal seizures ; development ; ATP ; purinergic signalling ; P2X7 receptor ; endometriosis ; adenosine ; P2Y ; P2X ; ectonucleotidases ; pain ; inflammation ; endometrium ; CD73 ; CD39 ; P2Y2 receptor ; P2X4 receptor ; canine ; dog ; DH82 ; macrophage ; neuroinflammation ; antinociception ; cerebral ischemia ; oxygen-glucose deprivation ; A2B receptors ; oligodendrocyte differentiation ; demyelination ; retina ; purinergic modulation ; glycinergic neurotransmission ; microglia ; neurodegeneration ; glycine transporters ; guanosine ; stroke ; neuroprotection ; purinergic signaling ; purinergic receptors ; autoimmune disease ; astroglia ; G protein-coupled receptor 17 (GPR17) ; neurite outgrowth ; montelukast ; NG2 ; ex vivo organotypic brain slice co-culture ; neurodegeneration and neuroregeneration ; n/a ; macrophages ; P2X7R ; pore formation ; inflammasome activation ; inflammatory diseases ; gallic acid ; visceral pain ; depression ; hippocampus ; spinal cord ; dorsal root ganglion ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 57
    Publication Date: 2024-04-02
    Description: This study analyzes coordination of international and national entities managing the Syrian refugee response in urban areas in Jordan and Lebanon and provides recommendations on improving coordination strategies and practices. It presents a new framework for planning, evaluating, and managing refugee crises in urban settings, both in the Syrian refugee crisis as well as other such situations going forward.
    Keywords: History ; Political Science ; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFH Migration, immigration and emigration ; thema EDItEUR::5 Interest qualifiers::5P Relating to specific groups and cultures or social and cultural interests::5PB Relating to peoples: ethnic groups, indigenous peoples, cultures and other groupings of people::5PBC Relating to migrant groups / diaspora communities or peoples
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  • 58
    Publication Date: 2024-04-02
    Description: Reports the findings of an evaluation by a panel of experts on the extent to which a suicide prevention media campaign in California is aligned with best practices in the field.
    Keywords: Psychology ; History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 59
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Afforestation/reforestation (or forestation) has been implemented worldwide as an effective measure towards sustainable ecosystem services and addresses global environmental problems such as climate change. The conversion of grasslands, croplands, shrublands, or bare lands to forests can dramatically alter forest water, energy, and carbon cycles and, thus, ecosystem services (e.g., carbon sequestration, soil erosion control, and water quality improvement). Large-scale afforestation/reforestation is typically driven by policies and, in turn, can also have substantial socioeconomic impacts. To enable success, forestation endeavors require novel approaches that involve a series of complex processes and interdisciplinary sciences. For example, exotic or fast-growing tree species are often used to improve soil conditions of degraded lands or maximize productivity, and it often takes a long time to understand and quantify the consequences of such practices at watershed or regional scales. Maintaining the sustainability of man-made forests is becoming increasingly challenging under a changing environment and disturbance regime changes such as wildland fires, urbanization, drought, air pollution, climate change, and socioeconomic change. Therefore, this Special Issue focuses on case studies of the drivers, dynamics, and impacts of afforestation/reforestation at regional, national, or global scales. These new studies provide an update on the scientific advances related to forestation. This information is urgently needed by land managers and policy makers to better manage forest resources in today’s rapidly changing environments.
    Keywords: QH301-705.5 ; Q1-390 ; SD1-669.5 ; simulation modeling ; shear strength ; stand structure ; vegetation restoration ; surface runoff ; soil and water conservation function ; soil enzymes ; riverbank ; evapotranspiration ; human activity ; afforestation ; Artemisia ordosica ; forest cover ; precipitation variation ; soil bioengineering ; base flow ; Poyang Lake Basin ; in situ calibration ; quantification ; chlorophyll fluorescence ; photoprotection ; remote sensing ; root distribution ; ecosystem model ; CASA ; afforestation ecosystem ; phenophase ; vegetation cover change ; soil characteristics ; Robinia pseudoacacia L. and Pinus tabulaeformis Carr. mixed plantations ; composted pine bark ; water-energy balance ; sediment load ; soil respiration ; energy partitioning ; soil microbial biomass ; transpiration ; net primary productivity ; spatio-temporal scales ; seedling quality ; peat moss ; fresh pine sawdust ; understory plants ; ring-porous trees ; different climatic conditions ; dye tests ; structural equation model ; Loess Plateau ; evapotranspiration (ET) ; Pinus engelmannii Carr. ; empirical statistics ; heat dissipation probes ; MODIS ; slope change ratio of cumulative quantities (SCRCQ) ; soil water balance ; LAI ; climate fluctuation ; BTOPMC model ; living brush mattress ; vegetation greening ; streamflow ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 60
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This Special Issue, entitled “Nutraceuticals and Functional Foods: Bridging Health and Food Under a New Perspective”, aims to approach the current state-of-the-art research on nutraceuticals and functional foods. The main issue in this field of research is the sustainability and recovery of bioactive substances from vegetal- or animal-origin byproducts to project and realize novel food supplements and nutraceuticals. Low environmental impact, safety, new food sources and analytical methodologies are of growing interest in the research area of food. The perspective approach addresses the mechanism of action of nutraceuticals, safety and functional foods and nutraceuticals’ mechanisms of action, revealing new possibilities for their use as tools in a complementary proactive approach to certain health issues to prevent the onset of health conditions or to be used in subjects who do not qualify for a conventional therapeutical approach. The areas involved in this perspective range from food chemistry and analysis to nutrition and from safety to sustainability; new therapeutical approaches and novel techniques of analysis and formulation are also involved, which require a wide inter- and multi-disciplinary approach. The overall assessment of these aspects creates new challenges for research and also impacts sustainability, health and safety. This Special Issue may also consider the bridging of health and food in their different declinations from a new perspective.
    Keywords: Food and by-products ; Functional foods and novel sources ; Health and beneficial properties ; Nutraceuticals and novel sources ; Prevention ; Clinical data ; In vitro and in vivo data ; Nanonutraceuticals and nanodelivery ; Clinical experience ; Formulation and novel sources ; Mechanism of action ; Analytical aspects ; Safety ; Interactions with active molecules. ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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  • 61
    Publication Date: 2024-04-02
    Description: Daunting challenges lie ahead for Arab countries where revolutions have upended longstanding authoritarian regimes. This monograph aims to help policymakers understand the challenges ahead, form well-founded expectations, shape diplomatic approaches, and take practical steps to foster positive change.
    Keywords: Political Science ; Sociology ; History ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GT Interdisciplinary studies::GTP Development studies
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  • 62
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually partitioned into three distinct regions, known as classes I, II, and III, which, to varying extents, can be found conserved in nonmammalian jawed vertebrates, such as bony fish, amphibians, and bird lineages. The MHC gene region is characterized particularly by the expression of class I and class II glycoproteins that bind peptides derived from intracellular or extracellular antigens to circulating T-cells. While this expressed antigenic specificity remains the predominant interest with respect to MHC function and polymorphism in a population, a broader concept has emerged that examines the MHC as a multifunctional polymorphic controller that facilitates and regulates genome diversity with a much greater array of functions and effects than just MHC-restricted antigen recognition. This volume of 19 reprints presented by various experts and collected from the Special Issue of Cells on “MHC in Health and Disease” covers a broad range of topics on the genomic diversity of the MHC regulatory system in various vertebrate species, including MHC class I, II, and III genes; innate and adaptive immunity; neurology; transplantation; haplotypes; infectious and autoimmune diseases; fecundity; conservation; allelic lineages; and evolution. Taken together, these articles demonstrate the immense complexity and diversity of the MHC structure and function within and between different vertebrate species.
    Keywords: QH301-705.5 ; Q1-390 ; HCP5 ; n/a ; camels ; MHC ; STK19 ; major histocompatibility complex ; human papillomavirus (HPV) ; T-cell receptor ; T1DGC ; bottleneck ; micro-mini-pigs ; life history ; computational analysis ; hepatocellular carcinoma ; phase ; Bactrian camel ; NSDK ; melanoma ; antigen ; autoimmune disease ; RD ; selection ; disease resistance ; autoimmunity ; ancestral haplotype ; Ski complex ; DXO ; high-throughput sequencing ; conservation genetics ; SVA ; lncRNA ; ankylosing spondylitis ; MHC genes ; viral peptides ; competing endogenous RNA (ceRNA) ; astrogliosis ; birds ; long-fragment super haplotype ; SNP ; RLR ; HLA polymorphism ; 5??3? RNA decay ; expression ; 3??5? mRNA turnover ; orthology ; long-read sequencing ; disease association ; dromedary ; polyomavirus ; MHC-II-associated sperm-egg recognition ; experimental medicine ; single nucleotide polymorphism (SNP) ; fish ; SKIV2L ; production trait ; molecular dynamics simulation ; Macaca fascicularis ; human endogenous retrovirus (HERV) ; concerted evolution ; polymorphism ; Old World camels ; MHC polymorphism ; protocol ; nonclassical ; gene duplication ; microglial reaction ; human leukocyte antigen-E ; SKI2W ; quantitative trait loci (QTL) studies ; antiviral immunity ; human immunodeficiency virus (HIV) ; founder effect ; giant panda ; domain movements ; BK virus ; promoter-proximal transcriptional pause ; type 1 diabetes (T1D) ; RP1 ; miR1236 ; KIR ; synaptic covering ; swine leukocyte antigen ; cynomolgus macaque ; HLA ; kidney transplantation ; ?2m knockout mice ; DOM3Z ; interferon ? ; ethnic populations in China ; ecology ; KIR–HLA pairs ; exosomes ; major histocompatibility complex (MHC) ; MHC-I-based mother-fetus recognition ; RNA quality control ; autoimmune diseases ; NELF-E ; haplotype ; genetic drift ; evolution ; nonhuman primate models ; HLA-B27 ; PNS/CNS interface ; risk genes ; pedigree ; MHC-I- and MHC-II-dependent inter-individual recognition ; regulation ; crested ibis ; reproductive performance ; nephropathy ; cancer ; nuclear kinase ; trichohepatoenteric syndrome ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    RAND Corporation
    Publication Date: 2023-10-05
    Description: This report is one of a series designed to support Air Force leaders in promoting resilience among its Airmen, civilian employees, and Air Force families. It examines the relationship between behavioral fitness and resilience, using key constructs found in the scientific literature that relate to sleep, alcohol use, and tobacco use.
    Keywords: Population Studies ; Health Sciences ; Management & Organizational Behavior ; History ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWG Air forces & warfare ; bic Book Industry Communication::M Medicine::MQ Nursing & ancillary services ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology::JHBD Population & demography
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; biorefinery ; polyphenols ; dynamic simulation ; Fucus distichus subsp. evanescens ; seaweeds ; phytochemicals ; Bifurcaria bifurcata ; Fucus vesiculosus ; kidney ; complex polysaccharides ; identification ; secondary metabolites ; phlorotannin ; cholinesterases ; eckol ; skin aging ; clinical trials ; dieckol ; fucoxanthin ; age-related macular degeneration ; photo-protection ; phytol ; Alzheimer’s disease ; fucosterol ; bone health ; nutraceutical ; papillomavirus ; red seaweed ; extraction ; osteoporosis ; fucoidan ; marine algae ; chemo-preventive agent ; ischemia-reperfusion injury ; hyperpigmentation ; bone metabolism ; bioactives ; macroalgae ; beta-secretase ; laurinterol ; prebiotics ; dietary fibre ; NMR spectroscopy ; health effects ; bromophenols ; beta-amyloid aggregation ; kahalalide F ; Padina pavonica ; carotenoids ; insulin glycation ; skincare ; mushroom tyrosinase ; polyunsaturated fatty acids ; fatty acid ; in vivo studies ; apoptosis ; algae ; biological activities ; Symphyocladia latiuscula ; Fucus serratus ; mass spectrometry ; Laminaria digitata ; high-speed counter-current chromatography ; isolation and purification ; K14HPV16 ; amyloid-? aggregation ; VEGF ; melanin ; Laurencia ; seaweed ; organotypic culture ; Saccharina latissima ; ex vivo ; genotoxicity assay ; gut microbiota ; phlorotannins ; eckmaxol ; high value applications ; Ecklonia maxima ; B16F10 ; neuroprotection ; linear diterpenes ; antitumoral ; Ecklonia cava ; cancer ; breast cancer explants ; osteosarcoma ; oxidative stress ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    RAND Corporation
    Publication Date: 2024-04-02
    Description: Examines the inconclusive results of the Israeli Defense Forces' operation in Lebanon after Hezbollah abducted two Israeli soldiers in 2006, which many believe represents a "failure of air power." The author demonstrates that this is an oversimplification of a more complex reality and contrasts the operation with Israel's counteroffensive against Hamas in the Gaza Strip in December 2008 and January 2009.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy
    Language: English
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  • 66
    Publication Date: 2023-10-05
    Description: In addition to the defeat of conventional enemy forces, Army units and leaders must be able to defeat unconventional forces, develop partner forces, protect local populations, and support civil functions. This report examines the adequacy of the Army Training and Leader Development (ATLD) system management processes, identifies areas for improvement, and develops directions that the Army could take to improve its ATLD management processes.
    Keywords: Business ; History ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV2 Personnel & human resources management ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWK Defence strategy, planning & research
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  • 67
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Nowadays, diet-related non-communicable diseases and their complications are one of the most important public health problems worldwide. Food supplements and functional foods are considered food products which contribute to the achievement of optimal nutritional well-being, health status, and quality of life through reducing the risk of diseases and promoting the appropriate function of human organs and systems. Nowadays, the assessment of these functional foods and the study of their implications in nutrition and health are important challenges in societies of developed countries where consumers increasingly demand foods with added value beyond the provision of nutrients and the satisfaction of appetite. In this reprint, the characterization of the nutritional composition and phytochemicals of functional foods and food supplements as well as the evaluation of their potential health benefits in different disorders and diseases through clinical trials or preliminary studies are addressed.
    Keywords: food supplement ; folic acid ; pregnancy ; food safety ; health claims ; nutrition ; Amazonian fruits ; composition ; metabolic effects ; royal jelly ; acetylcholine ; fatty acid ; ophthalmology ; dry eye ; magnesium ; pharmacy ; food supplements ; drugstore ; functional foods ; healthy eating ; credibility ; extrinsic attributes ; conjoint analysis ; Mediterranean diet ; phytonutrients ; dietary recommendations ; healthy diet ; polyphenols ; flavonoids ; carotenoids ; organosulfur ; caffeine ; antidiabetic activity ; antioxidant activity ; inhibition of α-glucosidase ; inhibition of α-amylase ; inhibition of collagenase ; kombucha ; bacteria ; yeast ; metagenome ; metabolome ; tea polyphenols ; antioxidants ; Glossogyne tenuifolia ; exercise ; forelimb grip strength ; lactate ; ammonia ; creatine kinase ; medium-chain triglycerides (MCTs) ; obesity ; energy expenditure ; diet-derived fat ; postprandial resting metabolism ; sedentary ; octanoic acid ; decanoic acid ; creatine ; magnetic resonance spectroscopy ; cost-effectiveness ; brain ; muscle ; healthcare ; anthocyanins ; organosulfur compounds ; tannins ; phenolic acids ; Persea americana ; non-alcoholic liver disease ; liver enzymes ; inflammation ; oxidative stress ; novel foods ; novel ingredients ; extracts ; risk assessment ; dietary supplements ; HPLC ; food authenticity ; neural tube defects ; food ; food analysis ; food ingredients ; infant formula ; kynurenic acid ; (poly)phenol-based supplement ; pharmacokinetics ; urinary excretion ; bioavailability ; inter-individual variability ; non-invasive brain stimulation ; TMS ; a-tDCS ; indicaxanthin ; brain food ; cortical excitability ; homeostatic plasticity ; trans-resveratrol ; regulation ; labels ; nutrition claims ; high-performance thin-layer chromatography ; HPTLC ; glutamine ; intestinal stem cells ; crypt ; proliferation ; burns ; micronutrient ; health claim ; labeling ; European legislation ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This book focuses on advanced research topics on human lactation, such as breastfeeding experiences, milk composition and production, COVID-19 and human milk, food allergens in human milk, the human milk microbiome, and the impacts of human milk on infant growth and development. The symposium proceedings aim to add diversity, passion, and innovation to lactation research and have a positive impact on mothers, infants, and communities worldwide, showcasing integrative mother/infant-centered research.
    Keywords: thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 69
    Publication Date: 2024-04-02
    Description: Through extensive primary source analysis and independent analysis, this report seeks to answer a number of important questions regarding the state of China’s armed forces. The authors found that the PLA is keenly aware of its many weaknesses and is vigorously striving to correct them. Although it is only natural to focus on the PLA’s growing capabilities, understanding the PLA’s weaknesses—and its self-assessments—is no less important.
    Keywords: History ; Political Science ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
    Language: English
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  • 70
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-01
    Description: This bookis the first monograph that provides a wholesome overview of the history of Antisemitism in Poland.The author critically analyzes the Polish manifestation of the gruesome phenomenon against the backdrop of historical events in all Europe, as she traces the formation of the ideology and its difference from Judeophobia. A special notion requires the author’s meticulousness in research of the archives referring to the Catholic Church and folk culture. Most importantly, she does not end with the historical perspective but uses her studies to shed light on the events permeating in the thirty years of the recent Polish history as an independent country.
    Keywords: Antisemitism ; Antisemitism Studies ; Antysemityzm ; Cala ; Enemy? ; Eternal ; History ; History of Persecutions ; Holocaust Studies ; jego ; Nisza ; odwieczny? ; Poland ; Polsce ; Trauma Studies ; wróg ; źródła ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Carboxylic acids are truly central compounds in cellular metabolism. Carbon dioxide is captured from the atmosphere through formation of carboxylic groups and is also released, in part, by decarboxylation reactions. The reactivity of the carboxylic group with amino- or hydroxyl-groups enables the formation of peptide and ester bonds. The functionality of the carboxylic group is also of huge importance in our industrial world for a wide range of applications. The loosely bound hydrogen provides weak acid functionality, much desired for food industry applications in preservatives and flavour compounds. Citric acid is one of our oldest industrial fermentation products. The presence of two carboxylic groups, or a combination of one carboxylic group and another functional group, make the compounds interesting building blocks for polymer production. A number of carboxylic acids, including, e.g., lactic, succinic, 3-hydroxypropionic and itaconic acids, have been identified and recognized as suitable platform chemicals for a foreseen growing carbohydrate based economy. Economic margins are, however, tight when competing with petroleum based production, and production strains, fermentation technology and—not least—downstream processing, all need to be improved to enable viable commercial production. This Special issue will cover current developments within this exciting field. Topics will include: Fermentation physiology of natural carboxylic acid producers; screening and isolation of novel producers; metabolic engineering for improving intrinsic carboxylic acid production; metabolic engineering for expanding product range to non-endogenous carboxylic acids; production from lignocellulosic derived sugars or by-product streams; downstream processing for recovery of carboxylic acids; bioprocess design—including continuous processes and integration. All production organisms—fungi, yeasts, bacteria—are welcome.
    Keywords: QH301-705.5 ; bioprocess design ; downstream processing ; metabolic engineering ; strain evolution ; fermentation physiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Beer is a beverage with more than 8000 years of history, and the process of brewing has not changed much over the centuries. However, important technical advances have allowed us to produce beer in a more sophisticated and efficient way. The proliferation of specialty hop varieties has been behind the popularity of craft beers seen in the past few years around the world. Craft brewers interpret historic beer with unique styles. Craft beers are undergoing an unprecedented period of growth, and more than 150 beer styles are currently recognized. This Special Issue, Brewing and Craft Beer, comprises nine different works by researchers from five continents (North America, South America, Europe, Africa, and Oceania). This Special Issue reflects thus a broad perspective on the most important questions that concern the researchers in different parts of the world.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; polyphenols ; n/a ; nutrient ; audible sound ; wet milling ; brewing technology ; robotics ; fast-screening ; lactose ; image analysis ; bottle refermentation ; beer aging ; sensory attributes ; brewing ; automation ; bitterness ; stout beer ; beer ; craft beer ; foamability ; Safrari ; adjuncts ; fermentation rate ; barley milling ; preference ; germ ; beer wort ; machine learning ; carbonation ; quality ; FAN ; granulometry ; sensory evaluation ; coffee ; beer acceptability ; computer vision ; fermentation ; economic contribution analysis ; short-chain fatty acids ; local value chain ; AEDA ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: The focus of the following work is the Russian author N.M. Karamzin (1766-1826), who is still known in Russia today for his sentimentalist narrative "Bednaja Liza" and the twelve-volume "Istorija gosudarstva rossijskogo". At the end of the 18th and in the first third of the 19th century, at the time of their creation, his works were widely read, Karamzin, as a sentimentalist writer as well as a historiographer, had some success in the contemporary reading public. The work is chronological, beginning with Karamzin's early work, Pisma Russkogo putešestvennika (1791-92), then examining a selection of sentimentalist narratives that appeared in the period 1792-1803 and ending with Istorija gosudarstva rossijskogo ", whose first eight volumes were published in 1818. Examined are the different discourses, which are assigned to the text categories travel writing, sentimentalistische povest 'and historiography, and others. in terms of narrative linkage.
    Description: Im Mittelpunkt der folgenden Arbeit steht der russische Autor N.M. Karamzin (1766-1826), der heute in Rußland noch durch seine sentimentalistische Erzählung "Bednaja Liza" sowie die zwölfbändige "Istorija gosudarstva rossijskogo" bekannt ist. Ende des 18. und im ersten Drittel des 19. Jahrhunderts, zur Zeit ihres Entstehens, wurden seine Werke viel gelesen, hatte Karamzin sowohl als sentimentalistischer Schriftsteller wie als Historiograph einigen Erfolg beim zeitgenössischen Lesepublikum. Die Arbeit geht chronologisch vor, sie beginnt mit dem Frühwerk Karamzins, den "Pisma russkogo putešestvennika" (1791-92), untersucht dann eine Auswahl der sentimentalistischen Erzählungen, die in der Zeit von 1792-1803 erschienen, und endet mit der "Istorija gosudarstva rossijskogo" , deren erste acht Bände 1818 veröffentlicht wurden. Untersucht werden die unterschiedlichen Diskurse, die den Textgattungen Reisebriefe, sentimentalistische povest' und Geschichtsschreibung zuzuordnen sind, und zwar u.a. im Hinblick auf narrative Verknüpfung.
    Keywords: History ; stories ; Ästhetischer ; Brinkjost ; Diskurs ; Geschichte ; Geschichten ; historiographischer ; Karamzin ; Povesti ; Reisebriefen zur Historiographie ; Sentimentalismus ; sentimentalistische Erzählung ; Systemtheorie ; thema EDItEUR::D Biography, Literature and Literary studies ; thema EDItEUR::N History and Archaeology::NH History
    Language: German
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: We are facing a complicated public health issue in the form of global drug shortages, including antibiotics. Synthetic biology empowers the next generation of antibiotics development, bringing us into a new era.
    Keywords: global regulator ; milbemycins ; Streptomyces bingchenggensis ; SspH ; actinorhodin ; avermectin ; ceftriaxone ; hepatotoxicity ; metal complexes ; oxidative stress ; Streptomyces ; comparative transcriptome ; polyether antibiotics ; salinomycin ; exporter genes ; spectroscopic studies ; antioxidant capacities ; hepatic functions ; cancer cells ; cefotaxime ; Inonotus hispidus ; natural product ; biological activity ; medicinal fungi ; phytochemicals ; antimicrobial agents ; biosynthetic pathway ; secondary metabolites ; 1-benzazepine ; l-kynurenine ; genome mining ; biosynthesis ; iterative methyltransferase ; genetic dereplication ; cyclodipeptide ; OSMAC ; cytotoxicity ; Zymomonas mobilis ; antibiotic resistance ; ampicillin ; genome editing ; CRISPR−Cas12a ; resistance selection markers ; traditional Chinese medicine ; antifungal drug ; immune regulation ; combination of drugs ; fungal infection ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 75
    Publication Date: 2024-04-14
    Description: In addition to an Information and Communication Technology infrastructure, a skilled labor force and a supportive environment are necessary to the balanced development of a knowledge-based economy. Without sufficient human capital and policies in place to promote the use of adopted technologies, their full potential may not be realized. This paper uses a cross-country perspective and various economic indicators to assess the development of Gulf Cooperation Council countries in the dimensions of a knowledge economy.
    Keywords: History ; Technology ; thema EDItEUR::U Computing and Information Technology::UB Information technology: general topics ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJK Communications engineering / telecommunications
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron–sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.
    Keywords: QH301-705.5 ; Q1-390 ; n/a ; regeneration ; posttranslational modification ; H2O2 ; chilling stress ; thioredoxin reductase ; X-ray crystallography ; photosynthesis ; Chlamydomonas reinhardtii ; protein ; monodehydroascorbate reductase ; methionine sulfoxide ; cysteine reactivity ; symbiosis ; plant ; MALDI-TOF mass spectrometry ; thioredoxins ; redox homeostasis ; methionine sulfoxide reductases ; redox ; redox signalling ; chloroplast ; protein-protein recognition ; cyanobacteria ; specificity ; wheat ; methanoarchaea ; stress ; redox regulation ; dough rheology ; methionine sulfoxide reductase ; electrostatic surface ; Calvin cycle ; ALAD ; metazoan ; Arabidopsis thaliana ; baking ; cold temperature ; macromolecular crystallography ; protein oxidation ; function ; methionine oxidation ; development ; iron–sulfur cluster ; tetrapyrrole biosynthesis ; legume plant ; glutathionylation ; Calvin-Benson cycle ; adult stem cells ; carbon fixation ; plastidial ; methionine ; redox active site ; ROS ; water stress ; NADPH ; repair ; physiological function ; signaling ; thioredoxin ; antioxidants ; glutathione ; glutaredoxin ; flavin ; Isocitrate dehydrogenase ; thiol redox network ; ageing ; disulfide ; mitochondria ; chlorophyll ; proteomic ; cysteine alkylation ; ferredoxin-thioredoxin reductase ; SAXS ; regulation ; oxidized protein repair ; ascorbate ; redox control ; nitrosylation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 77
    Publication Date: 2024-04-02
    Description: This report describes development of a statewide framework for evaluating and monitoring the short- and long-term impact of prevention and early intervention funding for mental health services on the California population. It details the approach, the data sources, and the frameworks developed: an overall approach framework and outcome-specific frameworks.
    Keywords: History ; Psychology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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    RAND Corporation
    Publication Date: 2024-03-29
    Description: Because soft airfields can support only a limited number of takeoffs and landings, it is important to understand how to maximize the cargo throughput at these soft fields. This report shows that there is an optimum landing weight that allows for maximum cargo delivery. This optimum landing weight is constant and independent of both aircraft ramp weight and the ability of the soil to resist compressive loads.
    Keywords: Transportation Studies ; History ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWC Military forces and sectors::JWCM Air forces and warfare ; thema EDItEUR::W Lifestyle, Hobbies and Leisure::WG Transport: general interest::WGM Aircraft and aviation
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  • 79
    Publication Date: 2024-04-02
    Description: This paper evaluates the short-term outcomes of students attending the National Alliance on Mental Illness’ Ending the Silence presentations, delivered across three high schools in a Northern California school district.
    Keywords: Psychology ; History ; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology::JHBC Social research and statistics
    Language: English
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  • 80
    Publication Date: 2023-10-05
    Description: This independent assessment is a comprehensive study of the strategic benefits, risks, and costs of U.S. military presence overseas. The report provides policymakers a way to evaluate the range of strategic benefits and costs that follow from revising the U.S. overseas military presence by characterizing how this presence contributes to assurance, deterrence, responsiveness, and security cooperation goals.
    Keywords: Business ; Technology ; History ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCS Economic systems & structures ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJM Management & management techniques::KJMV Management of specific areas::KJMV4 Management of real estate, property & plant ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWK Defence strategy, planning & research ; bic Book Industry Communication::T Technology, engineering, agriculture::TT Other technologies & applied sciences::TTM Military engineering
    Language: English
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-02
    Description: The book analyses the attitudes of non-EU countries towards European integration in historical and contemporary perspectives. The authors study a range of actors in Europe and beyond to explain the impact of the creation of the European Communities on the international system and how the EU is perceived in the world. The book further shows the significance of the institutional interplay within the EU, and between EU institutions, member states and external actors led by their own internal dynamics to explain policy outcomes. It investigates to what extent the perceptions of the international community towards the European Communities and the EU have been influenced by the complexity of their decision-making and the difficulty of reconciling the views of member states on key external relations issues. The authors also study the interplay of non-EU countries and the EU within the broader context of international and regional institutions and forums for international cooperation.
    Keywords: History ; European History ; European Policy ; Foreign Affairs ; European Union ; European History ; EU ; EU Institutions ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 82
    Publication Date: 2024-04-05
    Description: Sterols and other isoprenoids are of great interest for their molecular structure and function in cell architecture and evolution, as well as for their importance in medicine and agriculture. Molecules’ 2019 Festschrift Special Issue in honor of the 65th birthday of Prof. W. David Nes, an internationally recognized chemical biologist and recipient of the George Schroepher medal for sterol research, focuses on recent developments in the chemistry, biosynthesis, and function of these polycyclic natural products. This volume of Molecules contains 16 leading-edge review articles and original research contributions from an international cast of scientists. This volume is grouped into three sections: (i) isoprenoid metabolome and diversity, (ii) clinical evaluation of sterol and triterpene structures and biosynthesis, and (iii) methods and synthesis of steroids and other compounds. The volume will be a valuable reference tool for those who study medicinal chemistry, protein chemistry, and biochemistry of isoprenoid lipids.
    Keywords: QH301-705.5 ; QD415-436 ; Q1-390 ; high-fat high-carbohydrate diet ; toxicity ; oxysterol ; n/a ; squalene cyclase ; sterol content ; sterolomics ; Polystichum ; Smith-Lemli-Opitz syndrome ; antifungals ; alkaloid ; cycloartenol synthase ; degeneration ; phytosterol ; Rhizopus arrhizus ; fibroblasts ; pod-blast ; fern ; cholesterol ; cytotoxic activity ; N-methylpiperidine. reductive deamination ; genetic disease ; isoprenoid ; steroid ; atherosclerosis ; granatane ; antioxidant ; wound healing ; development ; enzyme-assisted derivatization ; maturity ; terpene ; keratinocytes ; C4-demethylation complex (C4DMC) ; ?-sitosterol ; mesocarp ; sterol biosynthesis ; mechanism-based inactivators ; Mucorales ; gas chromatography-mass spectrometry (GC-MS) ; Girard reagent ; ROS ; sterol pattern ; N-methylcadaverine ; ?-tocopherol ; electrospray ionization-mass spectrometry ; human African trypanosomiasis ; HUVECs ; lipidomics ; campesterol ; triterpene ; oxyphytosterol ; leishmania ; Chagas disease ; LOX-1 ; sterol C24-methyltransferase ; antifungal effectivity ; ergosterol biosynthesis ; hormone ; glucose homeostasis ; retina ; solanaceae ; cholestanoic acid ; algal sterols ; cell migration ; withanolides ; insulin resistance ; Zingiber officinale ; posaconazole ; synthesis ; pre-diabetes ; pharmacognosy ; sterol ; 4-methylsterol ; oleanolic acid ; antiparasitic drugs ; lupeol ; oilseed ; aurelianolides ; divalent metal co-factor ligation ; bile alcohol ; phytosterols ; azoles ; infectious disease ; gingerols ; UV-radiation ; oil bodies ; ZnO ; sterol 14?-demethylase ; stigmasterol ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 83
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Predation and scavenging are pervasive ecological interactions in both terrestrial and aquatic environments. The ecology, evolution and conservation of predators and scavengers have received wide scientific attention and public awareness. However, the close connection that exists between predation and scavenging has not been emphasized until very recently. The recognition that carnivorous animals may obtain meat by either hunting prey or scavenging their carcasses has profound implications from individual behavior to population, community and ecosystem levels. However, many relevant questions still remain unexplored. This book deals with some of these questions, with the final aim to definitively dismiss the traditional view that predation and scavenging are disconnected ecological processes. This compendium of science may help to inspire ecologists, evolutionary biologists, paleontologists, anthropologists, epidemiologists, forensic scientists, anatomists, and, of course, conservation biologists in their stimulating and promising endeavor of achieving a more comprehensive understanding of carnivory in a rapidly changing world.
    Keywords: caching ; Capreolus capreolus ; carrion ; Eurasian lynx ; Lynx lynx ; Norway ; predation ; roe deer ; scavenging ; decomposition ; nitrogen ; nutrient recycling ; trophic cascade ; apex predators ; bear ; interspecific interactions ; moose ; wolf ; birds of prey ; foraging ; predators ; scavengers ; vision ; carcass ; confrontational scavenging ; disease risk ; facultative scavenger ; landscape of peril ; marine ecosystems ; parasite risk ; predator risk ; terrestrial ecosystems ; anthropogenic food ; diet ; urban habitats ; ecological functions ; carnivorous ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Language: English
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The future food systems will have to provide food and nutrition security while facing unprecedented sustainability challenges: this underlines the need for a transition to more sustainable food systems. Taking into account these premises and considering the complexity of food systems, this book aims to present original research articles, reviews, and commentaries concerning the following:Advancements in food and beverage;Dietary supplements, nutraceuticals, and functional food;Food allergy and public health;Food and nutritional toxicology;Food biotechnology and food processing;Food microbiology and food safety;Food packaging;Food safety and food inspection;Food security and environmental impacts;Food waste management;Nutrition and metabolism;Sustainable food systems and agro-ecological food production.
    Keywords: perceived consumer effectiveness ; green food consumption ; social trust theory ; social ideal theory ; psychological wellbeing ; China ; food additives ; food industry ; food safety ; health impacts ; maltitol ; metabolism ; sweeteners ; consumer’s perceptions and attitudes ; food security ; natural food products ; natural sweeteners ; sustainability ; food sovereignty ; reindeer herding ; food value chain ; Indigenous peoples ; COVID-19 pandemic ; the Arctic ; Western Siberia ; Yamal-Nenets Autonomous Okrug ; epistemic trust ; risk perception ; genetically modified food ; public acceptance ; partial least squares structural equation modeling ; community-based intervention ; diet ; home food availability ; home food environment ; sugar sweetened beverages ; fruit and vegetable intake ; Mediterranean diet ; Mediterranean diet pyramid ; sustainable diets ; environmental concerns ; nutrition ; food-based dietary guidelines ; migrants ; diabetes ; food habits ; culturally tailored diet ; transcultural mediator ; café ; green ambience ; Delphi method ; indicator design ; grain production ; spatial–temporal characteristic ; influencing factors ; the Huang-Huai-Hai Plain ; Crepis vesicaria L. subsp. taraxacifolia ; nutritional value ; phenolic profile ; chicoric acid ; antioxidant ; anti-inflammatory ; Brazil ; community restaurants ; food handlers ; food insecurity ; low-income ; COVID-19 ; families ; children ; food acquisition ; restaurants ; biofilms ; food microbiology ; dietary guidelines ; Mediterranean ; the USA ; Japan ; Argentina ; South Africa ; egg quality traits ; ginger ; immunity ; Japanese quail performance ; halal food performance ; availability ; healthy/nutritional factor ; accreditation ; clean/safe/hygiene factor ; trust ; attachment ; halal-friendly image ; retention ; muslim travelers ; Escherichia coli ; bacterial retention ; surface topographies ; meat exudate ; wipe cleaning ; conditioning film ; Cape Verde ; cereals ; metals ; dietary intake ; risk assessment ; Indigenous health ; food systems ; colonialism ; community-based ; participatory ; n/a ; dysphagia ; the elderly ; food products ; processing ; rheology ; texture ; capital endowment ; ecological cognition ; environment-friendly technology ; adoption level ; Hackman model ; environmental health ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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  • 85
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    Peter Lang International Academic Publishing Group
    Publication Date: 2021-02-10
    Description: This book tells the story of a generation of American and Australian women who embodied – and challenged – the prescriptions of their times. In the 1950s and early 60s they went to colleges and universities, trained for professions and developed a life of the mind. They were also urged to embrace their femininity, to marry young, to devote themselves to husbands, children and communities. Could they do both? While they might be seen as a privileged group, they led the way for a multitude in the years ahead. They were quietly making the revolution that was to come. Did they have ‘the best of all possible worlds’? Or were they caught in a double bind? Sylvia Plath’s letters tell of her delighted sense of life opening before her as a ‘college girl’. Her poetry, however, tells of anguish, of reaching for distant goals. Drawing on interviews, surveys, reunion books, letters, biographical and autobiographical writing from both American and Australian women, this cultural history argues that the choices that faced educated women in that time led to the revolution of the late 1960s and 70s. Something had to give. There are lessons here for today’s young women, facing again conflicting expectations. Is it possible, they ask, to ‘have it all’?
    Keywords: Gender studies: women and girls ; Educational strategies and policy ; History ; General and world history ; History of the Americas ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFS Social groups::JFSJ Gender studies, gender groups::JFSJ1 Gender studies: women ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; bic Book Industry Communication::H Humanities::HB History::HBT History: specific events & topics::HBTB Social & cultural history ; bic Book Industry Communication::J Society & social sciences::JN Education::JNA Philosophy & theory of education
    Language: English
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  • 86
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: In 2011, carbohydrates provided 63% of the dietary energy intake to the world’s population. Historically, carbohydrate-rich diets have been associated with good health and longevity but there has been a move away from traditional carbohydrate-rich diets, with refined carbohydrate taking much criticism for contributing to non-communicable disease. The aim of this Special Issue is to discuss the appropriate use of environmentally sustainable carbohydrate-rich foods in the modern diet in developing and developed countries in the context of prevention and treatment of non-communicable disease.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; satiety ; preload ; carbohydrate ; observational study ; body weight ; chronic disease risk ; postprandial ; isomaltulose ; qualitative ; glycaemic glucose equivalents ; mixed meal ; glycaemia ; obesity ; kiwifruit ; knowledge ; carbohydrates ; sugars ; timing ; sucrose ; CVD ; nutrition ; glycemia ; prebiotics ; intestinal biota ; glycemic response ; fibre ; T2DM ; low-carbohydrate diet ; ethnicity ; rice consumption ; activity ; fruit ; exercise ; discussion groups ; potato ; resistant starch ; pasta ; type 2 diabetes mellitus ; glycemic index ; vitamin C ; carbohydrate exchanges ; fructose ; glycemic load ; Japanese diet ; rice ; type 2 diabetes ; glycaemic response ; dietary pattern ; insulinaemia ; diabetes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 87
    Publication Date: 2024-04-05
    Description: Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems.
    Keywords: QH301-705.5 ; Q1-390 ; parent-of-origin effects ; fluorescent in situ hybridization ; coverage ratio analysis ; n/a ; ribosomal DNA ; reactivation ; cytogenetics ; epigenetics ; heterochromatin ; interphase nucleus ; whole genome resequencing ; transmission ; grasshoppers ; genome instability ; dot-like (micro) Bs ; ?s ; B chromosome ; supernumerary elements ; transcription of heterochromatin ; maternal X chromosome ; supernumerary chromosome ; population analysis ; supernumerary ; repeat clusters ; extra chromosomes ; genes ; tandem repeats ; B morphotypes ; repetitive DNA ; repetitive elements ; DNA copy number variation ; chromosome polymorphism ; satellite DNA ; mammals ; maize B chromosome ; additional chromosomes ; inactivation ; drive ; B chromosomes ; FISH (fluorescence in situ hybridisation) ; organelle DNA ; Orthoptera ; origin ; supernumerary chromosomes ; karyotype evolution ; GISH (genomic in situ hybridisation) ; DNA composition ; de novo centromere formation ; genomics ; paternal X chromosome ; euchromatin degradation ; supernumerary chromosomal segments (SCS) evolution ; centromere ; sSMC ; Prospero autumnale complex ; next-generation sequencing ; Drosophila ; host/parasite interaction ; Apodemus peninsulae ; genome evolution ; evolution ; teleost ; chromosome evolution ; microdissected DNA probes ; controlling element ; mobile element ; RNA-Seq ; karyotypes ; karyotypic characteristics ; RepeatExplorer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 88
    Publication Date: 2023-10-05
    Description: Assesses the military space challenges facing the Air Force and the nation in light of the findings and recommendations of the Space Commission. The author reviews the Air Force's involvement in space since its creation as an independent service in 1947; examines the circumstances that occasioned the commission's creation and the conceptual and organizational roadblocks that have impeded a more rapid growth of U.S. military space capability; and enumerates the challenges facing the Air Force with respect to space.
    Keywords: History ; Political Science ; Technology ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWG Air forces & warfare ; bic Book Industry Communication::T Technology, engineering, agriculture::TR Transport technology & trades::TRP Aerospace & aviation technology
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  • 89
    Publication Date: 2023-10-05
    Description: Policymakers have become increasingly concerned in recent years about the possibility of future maritime terrorist attacks. Though the historical occurrence of such attacks has been limited, recognition that maritime vessels and facilities may be particularly vulnerable to terrorism has galvanized concerns. In addition, some plausible maritime attacks could have very significant consequences, in the form of mass casualties, severe property damage, and attendant disruption of commerce. Understanding the nature of maritime terrorism risk requires an investigation of threats, vulnerabilities, and consequences associated with potential attacks, as grounded both by relevant historical data and by intelligence on the capabilities and intentions of known terrorist groups. These risks also provide the context for understanding government institutions that will respond to future attacks, and particularly so with regard to the U.S. civil justice system. In principle, civil liability operates to redistribute the harms associated with legally redressable claims, so that related costs are borne by the parties responsible for having caused them. In connection with maritime terrorism, civil liability creates the prospect that independent commercial defendants will be held responsible for damages caused by terrorist attacks. This book explores risks and U.S. civil liability rules as they may apply in the context of these types of attacks.
    Keywords: History ; Political Science ; Law ; bic Book Industry Communication::J Society & social sciences::JW Warfare & defence::JWF Naval forces & warfare ; bic Book Industry Communication::L Law::LB International law::LBD International law of transport, communications & commerce::LBDM International maritime law
    Language: English
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  • 90
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The authentication of foods and beverages is a very current topic of great interest for all the actors involved in the food chain, including the food industry, consumers, and food science researchers. Food authenticity covers many different aspects related to mislabeling, adulteration, and misleading claims about origin, production methods, or processing technologies. As many factors may affect the chemical composition of foods (e.g., geographical origin, variety or breed, conditions of cultivation, and breeding and/or feeding), the implementation of accurate, robust, and high-throughput analytical methods is needed to assess their authenticity and traceability and, consequently, guarantee their safety and quality in terms of organoleptic, nutritional, and bioactive characteristics. For these purposes, multiple analytical tools can be employed in combination with advanced chemometrics, such as spectroscopic and chromatographic techniques, DNA-based methods, and state-of-the-art omics approaches. In this context, in 2020, the journal Foods launched the Special Issue “Food Authentication: Techniques, Trends and Emerging Approaches” to gather research papers and review articles dealing with the development and application of analytical techniques and emerging approaches in food authentication. Considering the success and popularity of this earlier Special Issue, we will now release a second Special Issue comprising ten valuable scientific contributions, including one review article, one commentary article, and eight original research articles.
    Keywords: rapid authentication ; handheld Raman ; NIR ; fatty acid profile ; oil qualification ; coffee authenticity ; HPLC-UV ; HPLC-FLD ; fingerprinting ; chemometrics ; food adulteration ; chicory ; barley ; flours ; fourier-transform infrared (FT-IR) spectroscopy ; second-derivative spectrum ; red pepper powder ; geographical origin ; discriminant analysis ; SDS method ; Qiagen method ; polymerase chain reaction (PCR) ; multiple attribute decision making (MADM) analysis ; Aerodramus ; coffee ; fermentation ; gastrointestinal tract ; Kopi Luwak ; civet ; characterization ; Fourier-transform infrared spectroscopy ; cluster analysis ; Sherry vinegar ; spectralprint ; random forest ; support vector machine ; molecular traceability ; authentication ; agri-food ; molecular markers ; DNA barcoding ; isothermal amplification ; sequencing ; alkaline phosphatase determination ; PDO Pecorino Siciliano cheese ; raw milk determination ; vinegar ; protected designation of origin ; UV-Vis spectroscopy ; prediction ; sterols ; olive oil ; triterpenic dialcohols ; supported liquid extraction ; high performance liquid chromatography ; gas chromatography ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Several epidemiological studies have demonstrated that oxidative stress is associated with a number of health disorders, including cardiovascular malfunction, certain types of cancer, diabetes mellitus, many other auto-immune diseases, and even ageing. The body possesses multiple mechanisms to counteract oxidative stress, which employ antioxidant compounds that are either naturally generated in situ (endogenous antioxidants) or externally supplied through food (exogenous antioxidants). These antioxidants are able to counteract oxidative stress, thanks to their ability to neutralize excess free radicals and protect the cellular lipids, proteins, and DNA from molecular damage. Exogenous antioxidants from the diet are of increasing interest because of their beneficial role in maintaining good health and in preventing chronic diseases. Indeed, a diet rich in dietary antioxidants, especially from fruits and vegetables, has been correlated with a successful prevention and lower incidence of several degenerative pathologies, including obesity, diabetes, cardiovascular diseases, and cancer. This Special Issue of Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature, examining the role of diets rich in antioxidant compounds in the prevention of chronic diseases and the characteristics of the antioxidants included in such diets.
    Keywords: QH301-705.5 ; antioxidants ; chronic diseases ; dietary supplementation ; human health ; prevention ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 92
    Publication Date: 2024-04-04
    Description: Implementing risk management principles for large defense acquisition programs is a priority for the U.S. defense acquisition community. To assist decisionmakers responsible for identifying major weapons programs’ risks, RAND developed a methodology and accompanying Excel risk tool (the “Assessor Tool”). It offers an approach to the evaluation of system integration risk for assessors such as Office of the Secretary of Defense staff.
    Keywords: Technology ; History ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
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  • 93
    Publication Date: 2024-04-02
    Description: California’s Mental Health Services Act of 2004 mandates the state and counties to develop mental health prevention and early intervention services and education. This document summarizes first-year findings from an ongoing evaluation of one element of that program, an initiative to prevent suicide.
    Keywords: Psychology ; History ; Health Sciences ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 94
    Publication Date: 2024-04-02
    Description: Less than two years since the beginning of the uprising in Syria, localized protests have morphed into full-blown civil conflict, and external actors have become involved as well. RAND conducted an analytic exercise to generate a greater understanding of the parties and issues in play, including the actors, their motivations, and potential impact of their activities.
    Keywords: History ; Technology ; thema EDItEUR::N History and Archaeology::NH History::NHG Middle Eastern history ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTM Military engineering
    Language: English
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  • 95
    Publication Date: 2023-10-05
    Description: In the wake of the 2008 financial crisis, conflicting arguments have been made about fair value accounting (FVA) versus historical cost accounting (HCA) and the role that each played in the crisis. This report examines the relationship between both types of accounting practices and systemic risk in the financial sector, providing recommendations on how FVA and HCA can both be improved.
    Keywords: Finance ; Law ; History ; bic Book Industry Communication::K Economics, finance, business & management::KF Finance & accounting::KFF Finance::KFFK Banking ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; bic Book Industry Communication::L Law::LN Laws of Specific jurisdictions::LNP Financial law::LNPB Banking law
    Language: English
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  • 96
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Biocontrol of plant diseases is considered one of the most important and current challenges of our society due to the need to look for eco-friendly alternatives to chemicals. Thus, research towards the biological control sensu lato [antagonist microorganisms, biostimulants, Induced Resistance (IR)] of plant diseases is an urgent demand for the agro-food sector of the Euroregion as well as for our society in the frame of the European Green Deal. Exploring different biocontrol tools as well as their combined effect against plant diseases is essential to generate knowledge on such topics to look for optimum management strategies in crop protection in the frame of organic and sustainable agriculture. Within this framework, this Special Issue of Plants brings together a collection of research papers on applied plant pathology and targeted reviews of biocontrol, including studies on antagonist microorganisms, biostimulants, and host resistance-inducers against plant diseases.
    Keywords: biological control agents ; biostimulation ; resistance host inducers ; sustainable agriculture ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 97
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Recent special issues in various journals have focused on “urban ecosystem services”. There is also an increasing amount of studies on “urban ecology”, “urban tree management”, “arboriculture”, “urban biodiversity”, and “ecosystem services” from wildland forests. This Special Issue aims to fill a void and focus on the socio-ecological diversity and the economic value of the ecosystem services from urban and peri-urban forests. Urban and peri-urban forests are tree dominated ecosystems in and near human settlements, while ecosystem services are the direct economic, social, and environmental benefits provided by their structural components and ecological functions.
    Keywords: QH301-705.5 ; GE1-350 ; Perceptions and attitudes ; Climate change ; Socio-ecological systems ; Ecosystem service tradeoffs ; Non-market valuation ; Urban forest structure and biodiversity ; Management and planning ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 98
    Publication Date: 2024-04-02
    Description: In 2013, the United States opted to cancel Phase 4 of its European Phased Adaptive Approach missile defense system. Russia had cited it as a threat to its nuclear deterrent. This report demonstrates that the restructured U.S. system is able to defend against a range of current and future Iranian missile threats and does not pose a threat to Russian intercontinental ballistic missiles.
    Keywords: Political Science ; History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWM Weapons and equipment::JWMN Nuclear weapons ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWK Military and defence strategy ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSF Arms negotiation and control
    Language: English
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  • 99
    Publication Date: 2023-10-05
    Description: Part of a series highlighting innovative models and best practices for leveraging local health departments’ involvement in Patient Protection and Affordable Care Act outreach and enrollment, this report describes a case study on Boston and Massachusetts that captures nuanced differences in how health departments support these efforts, identifies facilitators and barriers to these approaches, and develop lessons learned from these activities.
    Keywords: Health Sciences ; History ; Business ; bic Book Industry Communication::K Economics, finance, business & management::KF Finance & accounting::KFF Finance::KFFN Insurance & actuarial studies ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBQ Medicolegal issues ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBN Public health & preventive medicine
    Language: English
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  • 100
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: Outbreaks of crown-of-thorns starfish (Acanthaster spp.) are a major contributor to ongoing coral loss on reefs throughout the Indo-Pacific, thereby jeopardizing productivity and biodiversity of these important marine ecosystems. Controlling outbreak populations of Acanthaster spp. is considered one of the most promising strategies to halt or reverse widespread declines in live coral cover. Effective management of crown-of-thorns starfish is, however, conditional on improved understanding of their biology and ecology. While crown-of-thorns starfish are arguably the most extensively studied of any single coral reef species, there remain considerable gaps in our knowledge of their basic biology and ecology. This edited monograph presents the latest research and significant advances in understanding and managing outbreaks of crown-of-thorns starfish.
    Keywords: QH301-705.5 ; Coral reefs ; Habitat loss ; Disturbance ; Ecology ; Management ; Acanthaster spp. ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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