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  • Frontiers Media SA  (2,450)
  • Peter Lang International Academic Publishing Group  (1,660)
  • American Meteorological Society
  • Annual Reviews
  • Springer
  • English  (3,189)
  • German  (1,333)
Collection
  • 1
    Description / Table of Contents: Prof. Dr. -Ing. Wolfgang Spyra Brandenburg University of Technology in Cottbus, Germany The demilitarization and conversion of military properties wor- wide has been a topic of growing importance since the end of the Cold War. The slowing of the arms race brought on by weapons treaties and relaxed tensions between NATO and Warsaw Pact nations caused sto- piles of conventional weapons to become superfluous. The need to process and dispose of such weapons began more quickly in NATO countries. This demilitarization process began shortly after the reunification of Germany and was largely completed by the mid to late 1990’s. The remaining process, no small task in itself, of converting lands formerly used by the military into safe and environmentally acceptable landscapes may continue for decades to come. Due to a lack of resources and technology, the process of demilitarization in the former Warsaw Pact countries has launched more slowly. In 2002 both Georgia and Moldova finished projects which destroyed their stocks of liquid ballistic missile components. Both these projects were carried out through the cooperative support of trans-national organizations, private contractors, and research institutions. The Republic of Azerbaijan now finds itself at the beginning of its demilitarization process. Stored at the country’s military depots are over 2000 tons of missile fuels, oxidizer, and chemical additives. This hazardous waste is kept in tanks intended only for temporary transport and storage.
    Pages: Online-Ressource (X, 148 pages)
    ISBN: 9781402023811
    Language: English
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  • 2
    Keywords: communication ; design ; dynamics ; environment ; network ; physics ; power transmission ; radio ; satellite ; simulation ; technology ; transmission
    Description / Table of Contents: The 17 chapters of this book grew out of the tutorial lectures given by leading world-class experts at the NATO Advanced Research Workshop “Effects of Space Weather on Technology Infrastructure” - ESPRIT, which was held in Rhodes on March 25-29, 2004. All manuscripts were refereed and subsequently meticulously edited by the editor to ensure the highest quality for this monograph. I owe particular thanks to the lecturers of the ESPRIT Advanced Research Workshop for producing these excellent tutorial reviews, which convey the essential knowledge and the latest advances in our field. Due to the breadth, extensive literature citations and quality of the reviews we expect this publication to serve extremely well as a reference book. Multimedia material referring to individual chapters of the book is accessible on the accompanying CD. The aim of ESPRIT was to assess existing knowledge and identify future actions regarding monitoring, forecasting and mitigation of space weather induced malfunction and damage of vital technological systems operating in space and on the ground.
    ISBN: 9781402027543
    Language: English
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  • 3
    Keywords: Air ; Chlor ; GSM-Postponed Project ; Manual ; Oxide ; Water ; bacteria ; microorganism ; pollution ; production ; soil ; toxicity
    Description / Table of Contents: Environmental Chemistry: Fundamentals, by Jorge Ibanez et al., is an exceptionally useful and well organized book. After reviewing basic chemical concepts, Environmental Chemistry: Fundamentals quickly progresses to more advanced and contemporary applications including ozone depletion, physiochemical and biological treatment of pollutants, and green chemistry. The chemistry of processes of the atmosphere, lithosphere and hydrosphere are covered in detail and the effects of pollutants on each of these chemical processes are extensively considered, as are their effects on the biosphere. The book also has an experimental companion, Environmental Chemistry: Microscale Laboratory Experiments, which includes an array of environmental chemistry experiments that can be readily performed at the microscale level. Ideas for additional open-ended projects are provided for all experiments, and they impart a thorough introduction to environmental experimentation. I strongly recommend Environmental Chemistry: Fundamentals and its experimental accompaniment, Environmental Chemistry: Microscale Laboratory Experiments. Dr. Zvi Szafran Vice President for Academic Affairs and Professor of Chemistry Southern Polytechnic State University Our Earth is a remarkable reaction vessel. It is of paramount importance that students grow in their understanding and awareness of the astounding effects that chemistry and biochemistry have on our environment…and why they are so significant to our present and future hopes as a civilization. Environmental Chemistry: Microscale Laboratory Experiments, intended to complement lessons in the companion textbook Environmental Chemistry: Fundamentals, covers the chemical and biochemical processes that take place in air, water, soil, and living systems. The corresponding experiments range from the characterization of aqueous media to pollutant-treatment schemes. For increased safety, as well as for reduced costs, wastes, and environmental damage, the experiments are presented at the microscale level. Pre- and post-laboratory exercises and open-ended projects accompany each experiment, to develop problem-solving skills and initiative among students.
    Pages: Online-Ressource (XII, 238 pages)
    ISBN: 9780387494937
    Language: English
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  • 4
    Keywords: Atom ; Fulleren ; Fullerene ; Nanocar ; Nanomaterial ; Nanotube ; Transport ; carbon nanotubes ; electricity
    Description / Table of Contents: The 2007 ARW “Using Carbon Nanomaterials in Clean-Energy Hydrogen Systems” (UCNCEHS’2007) was held in September 22–28, 2007 in the remarkable town Sudak (Crimea, Ukraine) known for its heroic and unusual fate. In the tradition of the earlier conferences, UCNCEHS’2007 meeting served as an multidisciplinary forum for the presentation and discussion of the most recent research on transition to hydrogen-based energy systems, technologies for hydrogen production, storage, utilization, carbon nanomaterials processing and chemical behavior, energy and environmental problems. The aim of UCNCEHS’2007 was to provide the wide overview of the latest scientific results on basic research and technological applications of hydrogen interactions with carbon materials. The active representatives from research/academic organizations and governmental agencies could meet, discuss and present the most recent advances in hydrogen concepts, processes and systems, to evaluate current progress and to exchange academic information, to identify research needs and future development in this important area. This ARW should help further the progress of hydrogen-based science and promote the role of hydrogen and carbon nanomaterials in the energy field.
    ISBN: 9781402088988
    Language: English
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  • 5
    Pages: Online-Ressource (XII, 543 Seiten)
    Edition: 3. Aufl.
    ISBN: 9783540345251
    Language: German
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  • 6
    Keywords: Biomass conversion ; Biotechnology ; Chemical Engineering ; Chemistry industry ; Industrial Chemistry ; Kent ; Riegel ; biochemical engineering
    Description / Table of Contents: Substantially revising and updating the classic reference in the field, this handbook offers a valuable overview and myriad details on current chemical processes, products, and practices. No other source offers as much data on the chemistry, engineering, economics, and infrastructure of the industry. The Handbook serves a spectrum of individuals, from those who are directly involved in the chemical industry to others in related industries and activities. It provides not only the underlying science and technology for important industry sectors, but also broad coverage of critical supporting topics. Industrial processes and products can be much enhanced through observing the tenets and applying the methodologies found in chapters on Green Engineering and Chemistry (specifically, biomass conversion), Practical Catalysis, and Environmental Measurements; as well as expanded treatment of Safety, chemistry plant security, and Emergency Preparedness. Understanding these factors allows them to be part of the total process and helps achieve optimum results in, for example, process development, review, and modification. Important topics in the energy field, namely nuclear, coal, natural gas, and petroleum, are covered in individual chapters. Other new chapters include energy conversion, energy storage, emerging nanoscience and technology. Updated sections include more material on biomass conversion, as well as three chapters covering biotechnology topics, namely, Industrial Biotechnology, Industrial Enzymes, and Industrial Production of Therapeutic Proteins.
    Pages: Online-Ressource (XIV, 1562 pages)
    ISBN: 9780387278438
    Language: English
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  • 7
    Keywords: Assessment ; Malaria ; Public Health ; Scale ; Weather ; climate change ; public health policy ; temperature
    Description / Table of Contents: Awareness that many key aspects of public health are strongly influenced by climate is growing dramatically, driven by new research and experience and fears of climate change and the research needed to underpin policy developments in area is growing rapidly . This awareness has yet to translate into a practical use of climate knowledge by health policy-makers. Evidence based policy and practice is the mantra of the health sector. If climate scientists are to contribute effectively to health policy at local and global scales then careful empirical studies must be undertaken – focused on the needs of the public health policy and decision-makers. Results presented at the Wengen conference make clear that the science and art of integrating climate knowledge into the control of climate sensitive diseases on a year to year time frame as well as careful assessments of the potential impacts of climate change on health outcomes over longer time frames is advancing rapidly on many fronts. This includes advances in the empirical understanding of mechanisms, methodologies for modeling future impacts, new partnership developments between the health and climate community along with access to relevant data resources, and education and training. In a rapidly evolving field this book provides a snapshot of these emerging themes.
    Pages: Online-Ressource (X, 232 pages)
    ISBN: 9781402068775
    Language: English
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  • 8
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: social-decision making ; animal behavior ; behavioral ecology ; animal collective behavior ; animal SDM ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 9
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-29
    Description: Ausgehend von der zunehmenden quantitativen Bedeutung der Auslandsverschuldung des Staates untersucht der Verfasser zunächst, ob eine derartige Verschuldung in der Lage ist, den inländischen Kapitalmarkt zu entlasten und die Zinsbelastung des Staates zu senken. Anschliessend werden die Auswirkungen auf Volkseinkommen, Beschäftigung und Preisniveau im Inland analysiert. Darüber hinaus wird gefragt, inwieweit die Auslandsverschuldung des Staates in der gegenwärtigen bundesdeutschen Situation als zahlungsbilanzpolitisches Instrument eingesetzt werden kann.
    Keywords: Auslandsverschuldung ; einer ; flexiblen ; Scheuer ; Staates ; Wechselkursen ; Wirkungen ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCB Macroeconomics::KCBM Monetary economics
    Language: German
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  • 10
    Publication Date: 2024-04-05
    Description: After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.
    Keywords: QD1-999 ; Q1-390 ; Nanoparticles ; Gene Therapy ; Immunotherapy ; bioimaging ; theranostics ; nanomaterials ; Drug delivery ; Nanomedicine ; Cancer ; Phototherapy ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 11
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    Peter Lang International Academic Publishing Group
    Publication Date: 2021-02-10
    Description: In einer umfangreichen Untersuchung widmen sich Dieter Maurer und Claudia Riboni den frühesten Zeichnungen und Malereien von Kindern und auf diese Weise der «untersten» Struktur des Bildhaften und Ästhetischen: Wie erscheinen, «entstehen» Bilder? Welche Eigenschaften, Strukturen und Entwicklungen lassen sich in frühen graphischen Äusserungen beobachten? Sind frühe Bilder Produkte oder Prozesse? Sind frühe Bildmerkmale allgemein, abhängig vom Kontext ihrer Produktion, oder individuell? Worin besteht frühe bildhafte Erkenntnis und Ästhetik? Auf welche allgemeinen Bestimmungen von «Bild» oder «Bildern» verweist die Bildgenese? Auf welche allgemeinen Aspekte des frühen symbolischen Verhaltens verweisen frühe Bilder? Die Ergebnisse ihrer Forschung an der Zürcher Hochschule der Künste werden fortlaufend im Rahmen der Reihe, deren vierter Band hier vorliegt, veröffentlicht.
    Keywords: Cognition and cognitive psychology ; Drawing and drawings ; The arts: general issues ; Pre-school and kindergarten ; Child, developmental and lifespan psychology ; bic Book Industry Communication::J Society & social sciences::JM Psychology::JMR Cognition & cognitive psychology ; bic Book Industry Communication::A The arts::AB The arts: general issues ; bic Book Industry Communication::A The arts::AF Art forms::AFC Painting & paintings ; bic Book Industry Communication::J Society & social sciences::JM Psychology::JMC Child & developmental psychology ; bic Book Industry Communication::J Society & social sciences::JN Education::JNL Schools::JNLA Pre-school & kindergarten
    Language: German
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  • 12
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    Peter Lang International Academic Publishing Group
    Publication Date: 2022-05-13
    Description: Designing a contract is often more of an economic than a legal problem. A good contract protects parties against opportunistic behavior while providing motivation to cooperate. This is where economics and, especially contract theory, may prove helpful by enhancing our understanding of incentive issues. The purpose of this book is to provide specific tools which will help to write better contracts in real world environments. Concentrating on moral hazard literature, this book derives a tentative checklist for drafting contracts. As an economic contribution to a field traditionally considered an art rather than a science, this treatment also gives much attention to methodological issues.
    Keywords: Agency ; Agency-Theorie ; Analysis ; Approach ; asymmetrische Information ; Contracts ; Joint Ventures ; Kontrakttheorie ; Methodology ; Netzwerk ; Outsourcing ; private Information ; Stremitzer ; Structured ; Theory ; Transaktionsbeziehung ; Vertrag ; Writing ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCA Economic theory & philosophy ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCG Economic growth
    Language: English
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  • 13
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    Springer Nature | Springer
    Publication Date: 2022-06-21
    Description: This open access book is about socio-spatial theory in, and the nature of, Nordic geography. From both historical and contemporary perspectives, the book engages with theorisations of geography in the Nordic countries. Including chapters by geographers from Denmark, Finland, Iceland, Norway and Sweden, it reflects how theories about the relations between the social and the spatial have been developed, adopted and critiqued in Nordic human geography in relation to a wide range of themes, concepts and approaches. The book also traces institutional developments, distinct geographical traditions and intellectual histories, as well as authors’ own experiences as geographers in and beyond the Nordic area. The chapters together introduce and engage with debates and discussions that permeate Nordic geography and allows readers a glimpse of geographical thinking and the role of socio-spatial theory in the Nordic countries. By providing insights into how geographical ideas emerge, travel and are translated and adapted in specific contexts, the book contributes to debates about historical-geographical situatedness and theorisations of geography.
    Keywords: History of Nordic geography ; Socio-spatial theory in Nordic Geography ; Debates within Nordic geography ; History of geographical thought ; Theoretical geographical perspectives and approaches ; Radical and Critical Geography ; History of university developments in the Nordic countries ; Auto-biographical reflections among Nordic geographers ; Nordic small state geopolitics ; Nordic racial exceptionalism ; Regional planning ; Geography and landscape ; Marxist theorisation of geography ; Mobility and rural-urban transformations ; Nordic gender geography ; Urban space ; Nordic social and cultural geography ; Politicisizing nature in Nordic geography ; Tourism studies in Nordic geography ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography::RGC Human geography ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology::JHBA Social theory ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
    Language: English
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  • 14
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: omics ; epigenetics ; pharmacogenetics ; CYP ; risk prediction ; microbiota ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacology
    Language: English
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  • 15
    Publication Date: 2024-04-11
    Description: It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. Therefore, we cannot reduce microalgae biology to what we have learned from land plants biology. However, we are still at the beginning of a comprehensive understanding of microalgae biology. Microalgae have been posited several times as prime candidates for the development of sustainable energy platforms, making thus the in-depth understanding of their biological features an important objective. Thus, the knowledge related to the basics of microalgae biology must be acquired and shared rapidly, fostering the development of potential applications. Microalgae biology has been studied for more than forty years now and more intensely since the 1970’s, when genetics and molecular biology approaches were integrated into the research programs. Recently, studies on the molecular physiology of microalgae have provided evidences on the particularities of these organisms, mainly in model species, such as Chlamydomonas reinhardtii. Of note, cellular responses in microalgae produce very interesting phenotypes, such as high lipid content in nitrogen deprived cells, increased protein content in cells under high CO2 concentrations, the modification of flagella structure and motility in basal body mutant strains, the different ancient proteins that microalgae uses to dissipate the harmful excess of light energy, the hydrogen production in cells under sulfur deprivation, to mention just a few. Moreover, several research groups are using high-throughput and data-driven technologies, including “omics” approaches to investigate microalgae cellular responses at a system-wide level, revealing new features of microalgae biology, highlighting differences between microalgae and land plants. It has been amazing to observe the efforts towards the development and optimization of new technologies required for the proper study of microalgae, including methods that opened new paths to the investigation of important processes such as regulatory mechanisms, signaling crosstalk, chemotactic mechanisms, light responses, chloroplast controlled mechanisms, among others. This is an exciting moment in microalgae research when novel data are been produced and applied by research groups from different areas, such as bioprocesses and biotechnology. Moreover, there has been an increased amount of research groups focused in the study of microalgae as a sustainable source for bioremediation, synthesis of bioproducts and development of bioenergy. Innovative strategies are combining the knowledge of basic sciences on microalgae into their applied processes, resulting in the progression of many applications that hopefully, will achieve the necessary degree of optimization for economically feasible large-scale applications. Advances on the areas of basic microalgae biology and novelties on the essential cellular processes were revealed. Progress in the applied science showed the use of the basic science knowledge into fostering translational research, proposing novel strategies for a sustainable world scenario. In this present e-book, articles presented by research groups from different scientific areas showed, successfully, the increased development of the microalgae research. Herewith, you will find articles ranging from bioprospecting regional microalgae species, through advances in microalgae molecular physiology to the development of techniques for characterization of biomass and the use of biomass into agriculture and bioenergy production. This e-book is an excellent source of knowledge for those working with microalgae basic and applied sciences, and a great opportunity for researchers from both areas to have an overview of the amazing possibilities we have for building an environmentally sustainable future once the knowledge is translated into novel applications.
    Keywords: TA1-2040 ; TP248.13-248.65 ; QK1-989 ; Q1-390 ; Biotechnology ; biomass ; Hydrogen ; bioenergy ; Nutrients ; Lipids ; Microalgae ; Biofuels ; sustainability ; Carbon Dioxide ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 16
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    Peter Lang International Academic Publishing Group
    Publication Date: 2021-02-10
    Description: Trotz ihrer gesamtwirtschaftlichen Bedeutung hat die kommunale Investitionstätigkeit nur ein geringes Interesse in der Finanzwissen- schaft gefunden. So ist bis heute weitgehend unbekannt, welche Motive eine Gemeinde veranlassen, Investitionsvorhaben in Angriff zu nehmen. Die Studie kommt an Hand empirischer Untersuchungen zu dem Ergebnis, dass die ökonomische Analyse kommunaler Investitionen nicht nur interessante finanzwissenschaftliche Aspekte eröffnet, sondern auch manche tradierte Vorstellung in Frage stellt.
    Keywords: Economics ; Political economy ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCS Economic systems & structures ; bic Book Industry Communication::J Society & social sciences::JP Politics & government::JPP Public administration
    Language: German
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  • 17
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: oligodendrocyte ; Schwann cell ; oligodendrocyte precursor cell ; myelin ; myelin repair ; axon physiology ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 18
    Publication Date: 2023-12-21
    Description: It is now well appreciated that the immune system, in addition to its traditional role in defending the organism against pathogens, communicate in a well-organized fashion with the brain to maintain homeostasis and regulate a set of neural functions. Perturbation in this brain-immune interactions due to inflammatory responses may lead to psychiatric and neurological disorders. Microglia are one of the essential cells involved in the brain-immune interactions. Microglial cells are now not simply regarded as resident tissue macrophages in the brain. These cells are derived from myeloid progenitor cells in the yolk sac in early gestation, travel to the brain parenchyma and interact actively with neurons during the critical period of neurogenesis. Microglia provide a trophic support to developing neurons and take part in the neural wiring through the activity-dependent synapse elimination via direct neuron-microglia interactions. Altered microglial functions including changes in the gene expression due to early life inflammatory events or psychological and environmental stressors can be causally related to neurodevelopmental diseases and mental health disorders. This type of alterations in the neural functions can occur in the absence of infiltration of inflammatory cells in the brain parenchyma or leptomeninges. In this sense, the pathogenetic state underlying a significant part of psychiatric and neurological diseases may be similar to “para-inflammation”, an intermediate state between homeostatic and classical inflammatory states as defined by Ruslan Medzhitov (Nature 454:428-35, 2008). Therefore, it is important to study how systemic inflammation affects brain health and how local peripheral inflammation induces changes in the brain microenvironment. Chronic pain is also induced by disturbance in otherwise well-organized multisystem interplay comprising of reciprocal neural, endocrine and immune interactions. Especially, early-life insults including exposure to immune challenges can alter the neuroanatomical components of nociception, which induces altered pain response later in life. Recently the discrete roles of microglia and blood monocyte-derived macrophages are being defined. The distinction may be further highlighted by disorders in which the brain parenchymal tissue is damaged. Therefore, studies investigating the dynamics of immune cells in traumatic brain injury and neurotropic viral infections including human immunodeficiency virus, etc. as well as neurodegenerative diseases such as amyotrophic lateral sclerosis are promising to clarify the interplay between the central nervous and immune systems. The understanding of the histological architecture providing the infrastructure of such neuro-immune interplay is also essential. This Frontiers research topic brings together fourteen articles and aims to create a platform for researchers in the field of psychoneuroimmunology to share the recent theories, hypotheses and future perspectives regarding open questions on the mechanisms of cell-cell interactions with chemical mediators among the nervous, immune and endocrine systems. We hope that this platform would reveal the relevance of the studies on multisystem interactions to enhance the understanding of the mechanisms underlying a wide variety of neurological and psychiatric disorders.
    Keywords: R5-920 ; RC346-429 ; RC581-607 ; brain-immune interaction ; fatigue ; pain ; HIV ; neuroinflammation ; traumatic brain injury ; depression ; microglia ; amyotrophic lateral sclerosis ; autism ; bic Book Industry Communication::M Medicine
    Language: English
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  • 19
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Eine "geistige Nähe" zwischen dem Repräsentanten des deutschen philosophischen Dramas und dem Schöpfer des russischen philosophischen Romans konstatierte der Germanist Vil'mont? Wenn in der russischen Literatur des 19. Jahrhunderts ein inneres Bedürfnis existiert hat, Schillersche Kunsterfahrungen in einem umfassenden Sinne zu assimilieren und umzufunktionieren, dann sind daraus auch Konsequenzen hinsichtlich eines typologischen Zusammenhanges zwischen aufklärerisch-klassischem Denken und russischem Realismus zu ziehen.
    Keywords: Aspekte ; Dostoevskijs ; Kunst ; Kunsttheorie ; Literaturkonzept ; Literaturwissenschaft ; Philosophie ; Russland ; Schillerschen ; Schulz ; Slavische Sprachwissenschaft ; thema EDItEUR::D Biography, Literature and Literary studies
    Language: German
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  • 20
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Die Arbeit besteht somit aus zwei Hauptteilen. Zunächst werden in den "Vorbemerkungen" die wichtigsten Begriffe gegeneinander abgegrenzt und ein Forschungsüberblick gegeben. Da die Entwicklung der russischen Sprache eng mit den jeweiligen geschichtlichen Ereignissen verknüpft ist, werden im ersten, mehr referierenden Teil die geschichtlichen Voraussetzungen für den Sprachwandel in einem kurzen Überblick dargelegt. Anschließend wird die sprachliche Umbruchsituation charakterisiert. Einen eigenen Abschnitt wird dabei die Einordnung des "Artakserksovo dejstvo" in den literarischen Kontext seiner Zeit bilden. Im zweiten Teil wird der Text des "Artakserksovo dejstvo" sprachlich untersucht.
    Keywords: Artakserksovo ; ausgehenden ; dejstvo ; Jahrhunderts ; Rußland ; Schellenberger ; Situation ; Sprache ; sprachlichen ; Studien ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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  • 21
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: The aim of this work is to integrate the West Slavic languages ​​into grammar and language comparisons using modern grammatical approaches. This is done using the example of the imperative sentence in Slovak with a view to other West Slavic languages. This type of sentence is examined for its formal and content-related characteristics. At the same time, its communicative-pragmatic potential is derived and explained from the structural meaning of this mode verbi. The demarcation between the grammar and the pragmatics of the imperative theorem will play an important role here.
    Description: Das Ziel dieser Arbeit ist es, die westslawischen Sprachen unter Anwendung moderner grammatiktheoretischer Ansätze in den Grammatik- und Sprachvergleich zu integrieren. Dies erfolgt am Beispiel des Imperativsatzes im Slowakischen mit Blick auf andere westslawische Sprachen. Dieser Satztyp wird hinsichtlich seiner formalen und inhaltlichen Eigenschaften untersucht. Zugleich wird sein kommunikativ-pragmatisches Potential aus der Strukturbedeutung dieses Modus verbi abgeleitet und erklärt. Dabei wird die Grenzziehung zwischen der Grammatik und der Pragmatik des Imperativsatzes eine wichtige Rolle spielen.
    Keywords: Blick ; Grammatik ; grammatiktheoretisch ; Imperativsatz ; Linguistik ; Pragmatik ; Satztyps ; Semantik ; Slavische Sprachwissenschaft ; Slowakischen ; Späth ; Sprachen ; Strukturbedeutung ; Syntax ; westslawische ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-04
    Description: Gesellschaften mit starker Einwanderung kennzeichnen vielfältige Formen von Identitätsbildung und das Ringen um politische und zivilgesellschaftliche Partizipation. Dies gilt in besonderer Weise für Luxemburg im 19. und 20. Jahrhundert. Hier entstand in einem Kleinstaat eine der jüngeren Nationen Europas und zugleich eine besonders offene, plurikulturelle Einwanderungsgesellschaft. Ziel dieses Bandes ist es, die Entstehung dieser Mehr-Kulturen-Gesellschaft im europäischen Zusammenhang zu verstehen. Die einzelnen Beiträge analysieren mit Hilfe unterschiedlicher sozial- und kulturwissenschaftlicher Annäherungen exemplarische Konfliktlinien der Identitätsbildung und des Kampfes um Partizipation.
    Keywords: European history ; Biography: general ; Language teaching and learning ; History ; Social and cultural history ; General and world history ; Literature: history and criticism ; Literary studies: ancient, classical and medieval ; Literary theory ; Philosophy ; Politics and government ; Civics and citizenship ; Political science and theory ; Political control and freedoms ; Anthropology ; Social and cultural anthropology ; Ethnic studies ; Gender studies: women and girls ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history ; thema EDItEUR::N History and Archaeology::NK Archaeology ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSF Gender studies, gender groups::JBSF1 Gender studies: women and girls ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory
    Language: German
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  • 23
    Publication Date: 2024-04-05
    Description: In the past two decades there have been significant advances made in understanding the cellular and molecular alterations that occur with brain ageing, as well as with our understanding of age-related brain diseases. Ageing is associated with a mid-life decline in many cognitive domains (eg. Attention, working memory, episodic memory) that progresses with advancing age and which may be potentiated by a variety of diseases. However, despite the breadth of attempts to explain it, the underlying basis for age-related memory impairment remains poorly understood. Both normal and “pathological” ageing (as in age-related neurodegenerative disorders such as Alzheimer’s disease) may be associated with overlapping and increased levels of “abnormal” pathology, and this may be a potential mediator of cognitive decline in both populations. An emerging hypothesis in this field is that metal ion dys/homeostasis may represent a primary unifying mechanism to explain age- and disease-associated memory impairment – either indirectly via an effect on disease pathogenesis, or by a direct effect on signaling pathways relevant to learning and memory. There remains a concerted worldwide effort to deliver an effective therapeutic treatment for cognitive decline associated with ageing and/or disease, which is currently an unmet need. There have been numerous clinical trials conducted specifically testing drugs to prevent cognitive decline and progression to dementia, but to date the results have been less than impressive, highlighting the urgent need for a greater understanding of the neurobiological basis of memory impairment in ageing and disease which can then drive the search for effective therapeutics.
    Keywords: RC321-571 ; Q1-390 ; Down Syndrome ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; aluminium ; Iron ; TBI ; Cognition ; Copper ; Alzheimer's disease ; Zinc ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 24
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: 〈P〉The authors of the articles are Slovak linguists who work within various spheres of linguistics. Represented in the volume are authors who started their scientific activity in the pre-war period, directly or indirectly building on the work of the Prague Linguistic Circle, but soon differentiating themselves and contributing to linguistic theory with original works, as well as a newer generation of linguists who entered linguistics within the last two decades. 〈/P〉
    Keywords: Kacala ; Linguistics ; Linguistik ; Prague Linguistic Circle ; pre-war period ; Reader ; Semantics ; Slavische Sprachwissenschaft ; Slovak ; Slovak linguists ; Studies ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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  • 25
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: 〈P〉Die 1972 von den Frankfurter Slavisten Olexa Horbatsch und Gerd Freidhof begründete Reihe Specimina philologiae Slavicae wird heute von Holger Kuße (Dresden), Peter Kosta (Potsdam), Beatrix Kreß (Hildesheim), Franz Schindler (Gießen), Barbara Sonnenhauser (Zürich) und Nadine Thielemann (Wien) herausgeben. In der Reihe erscheinen Monographien, Sammelbände und Lehrbücher zu allen Gebieten der Slavistik, der Sprach-, der Literatur- und der Kulturwissenschaft. In der Sprachwissenschaft erscheinen sowohl sprachhistorische als auch innovative Arbeiten zur Pragmatik und Semantik, zu slavischen Kleinsprachen und zur Diskurslinguistik. In der Literatur- und Kulturwissenschaft gehört zu den besonderen Interessensgebieten die Russische Philosophie.〈/P〉
    Keywords: České ; comparison ; Czech ; Degrees ; Linguistik ; Literatur ; Marvan ; Philologie ; Slawistik ; Sprachwissenschaft ; stupňování ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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  • 26
    Publication Date: 2024-04-04
    Description: Evolution of the horse has been an often-cited primary example of evolution, as well as one of the classic and important stories in paleontology for over a century and a half, due to their rich fossil record across 5 continents: North America, South America, Europe, Asia and Africa. The recent horse has served a profound role in human ancestry, including agriculture, commerce, sport, transport, warfare, and in prehistory, for the subsistence of humans. Many studies have examined the evolution of the Equidae and chronicled the striking changes in skulls, dentition, limbs, and body size which have long been perceived to be a response to environmental shifts through time. Most comprehensive studies heretofore have: (1) focused on the “Great Transformation”- changes that occurred in the early Miocene, (2) involved tracking long-term diversity or paleoecological trends on a single continent or within a geographical locality, or (3) concentrated on the 3-toed hipparions. The Plio–Pleistocene evolutionary stage of horse evolution is punctuated by the great climatic fluctuations of the Quaternary beginning 2.6 Ma which influenced Equus evolution, biogeographic dispersion and adaptation on a nearly global scale. The evolutionary biology of Equus evolution across its entire range remains relatively poorly understood and often highly controversial. Some of this lack of understanding is due to assumptions that have arisen because of the relatively derived craniodental and postcranial anatomy of Equus and its close relatives which has seemed to imply that that these forms occupied relatively homogenous and narrow dietary and locomotor niches - notions that have not been adequately addressed and rigorously tested. Other challenges have revolved around teasing apart environmentally-driven adaptation versus phylogenetically defined morphological change. Geochronologic age control of localities, geographic provinces and continents has improved, but in no way is absolute and can be reexamined in our proposed volume. Temporal resolution for paleodietary, paleohabitat and paleoecological interpretations are also challenging for understanding the evolution of Equus. Our proposed volume attempts to assemble a group of experts who will address multiple dimensions of Equus’ evolution in time and space.
    Keywords: Ecomorphology ; Equus ; Paleoecology ; Taxonomy ; Biogeography ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Language: English
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  • 27
    Publication Date: 2023-12-21
    Description: Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types have specific defects in DNA repair pathways, and that these defects may predispose for sensitivity and resistance to various classes of cytotoxic agents. Breast, ovarian and other cancers develop in the setting of inherited DNA repair deficiency, and these cancers may be more sensitive to cytotoxic agents that induce DNA strand breaks, as well as to inhibitors of PARP activity. A series of recent clinical trials has tested whether PARP inhibitors can achieve synthetic lethality in hereditary DNA repair-deficient tumors. At the current time, mutation of BRCA serves as a potential, but not comprehensive, biomarker to predict response to PARP inhibitor therapy. Mechanisms of resistance to PARP inhibitors are only recently being uncovered. Future studies seek to identify sporadic cancers that harbor genomic instability rendering susceptibility to PARP inhibitors that compound lethal DNA damage.
    Keywords: R5-920 ; RC254-282 ; DNA reapir ; PARP inhibitor ; Homologous Recombination ; combination therapy ; DNA Damage ; Cancer ; bic Book Industry Communication::M Medicine
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  • 28
    Publication Date: 2024-04-05
    Description: Neuromorphic engineering has just reached its 25th year as a discipline. In the first two decades neuromorphic engineers focused on building models of sensors, such as silicon cochleas and retinas, and building blocks such as silicon neurons and synapses. These designs have honed our skills in implementing sensors and neural networks in VLSI using analog and mixed mode circuits. Over the last decade the address event representation has been used to interface devices and computers from different designers and even different groups. This facility has been essential for our ability to combine sensors, neural networks, and actuators into neuromorphic systems. More recently, several big projects have emerged to build very large scale neuromorphic systems. The Telluride Neuromorphic Engineering Workshop (since 1994) and the CapoCaccia Cognitive Neuromorphic Engineering Workshop (since 2009) have been instrumental not only in creating a strongly connected research community, but also in introducing different groups to each other’s hardware. Many neuromorphic systems are first created at one of these workshops. With this special research topic, we showcase the state-of-the-art in neuromorphic systems.
    Keywords: RC321-571 ; Q1-390 ; neuromorphic engineering ; Learning ; Floating gate ; Neural Network ; spike-based ; event-based ; simulation ; dynamic vision sensor ; network ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 29
    Publication Date: 2023-12-21
    Description: This e-book provides the insight into occupational health and safety problems, challenges and solutions of the dairy sector. Thirty-two authors have been sharing their results and knowledge reflecting the challenges from small scale farming up to industrial style. The worldwide trend of growing farm sizes and a reduction in numbers is one of the major drivers for the changes in the working environment. Musculoskeletal disorders are among the most prevalent health problems of people working on farms. Nevertheless mechanisation has not reduced the number of complaints, and new problems arise due to the changing working environment.
    Keywords: R5-920 ; RA1-1270 ; immigrant workers ; Dairy farming ; OHS ; MSS ; MSD ; bic Book Industry Communication::M Medicine
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  • 30
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Despite the importance of mathematics in our educational systems little is known about how abstract mathematical thinking emerges. Under the uniting thread of mathematical development, we hope to connect researchers from various backgrounds to provide an integrated view of abstract mathematical cognition. Much progress has been made in the last 20 years on how numeracy is acquired. Experimental psychology has brought to light the fact that numerical cognition stems from spatial cognition. The findings from neuroimaging and single cell recording experiments converge to show that numerical representations take place in the intraparietal sulcus. Further research has demonstrated that supplementary neural networks might be recruited to carry out subtasks; for example, the retrieval of arithmetic facts is done by the angular gyrus. Now that the neural networks in charge of basic mathematical cognition are identified, we can move onto the stage where we seek to understand how these basics skills are used to support the acquisition and use of abstract mathematical concepts.
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; development ; numerosity ; gifted ; Mathematical Cognition ; algebra ; abstract ; Expertise ; Arithmetic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 31
    Publication Date: 2023-12-21
    Description: Microglia are essential for the development and function of the adult brain. Their ontogeny, together with the absence of turnover from the periphery and the singular environment of the central nervous system (CNS), make microglia a unique cell population compared to other tissue-macrophages. The unique properties and functions of microglial cells, such as their role in synaptic pruning or the exceptional capacity to scan the brain parenchyma and rapidly react to its perturbations, have emerged in recent years. In the coming years, understanding how microglia acquire and maintain their unique profiles in order to fulfil distinct tasks in the healthy CNS and how these are altered in disease, will be essential to develop strategies to diagnose or treat CNS disorders with an immunological component. This Research Topic covers several aspects of microglial biology, ranging from their origin and the functional role of microglia during development and lifespan, their molecular properties compared with other brain and peripheral immune cells to microglial phenotypes and functional states in neurodegenerative diseases and brain tumours. In conclusion, the present Research Topic provides a comprehensive overview of our current understanding of several cellular and molecular mechanisms that make microglia a unique immune cell population within the healthy CNS as well as under inflammatory, neurodegenerative and tumorigenic processes.
    Keywords: R5-920 ; RC346-429 ; RC581-607 ; inflammation ; brain tumour ; neurodegeneration ; microglia ; ontogeny ; bic Book Industry Communication::M Medicine
    Language: English
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    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Exercise Science ; Performance ; Physiology ; Japan ; Olympics ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 33
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-30
    Description: Die Betrachtung aggregierter Beschäftigungsentwicklungen greift zu kurz, wenn man sich für die Dynamik und die Unterschiedlichkeit betriebsindividueller Beschäftigungsveränderungen interessiert. Für diese Arbeit wurden daher erstmals für die baden-württembergische Industrie und die Jahre 1980 bis 1999 amtliche Betriebsdaten zu einem Betriebspaneldatensatz verknüpft. Ausgehend von einer fundierten Analyse der betrieblichen Arbeitsplatzdynamik werden mögliche betriebsindividuelle, branchenspezifische, aber auch regionale Einflussfaktoren des betrieblichen Beschäftigungswachstums einer empirischen Überprüfung unterzogen. Eine ökonometrische Analyse möglicher Determinanten des Auftretens und insbesondere des Überlebens von neu gegründeten Industriebetrieben rundet die Arbeit ab.
    Keywords: amtlichen ; Analyse ; Arbeitsplatzdynamik ; baden ; Betriebspaneldaten ; Eine ; Industrie ; industrie ; neue wirtschaften ; standort ; Strotmann ; württembergischen ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCA Economic theory and philosophy ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCF Labour / income economics ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCS Economic systems and structures
    Language: German
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  • 34
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: organohalide respiration ; Microbial reductive dehalogenation ; Dehalococcoides ; electron transport chain ; reductive dehalogenase ; Community composition and function ; bioremediation ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 35
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-29
    Description: In der EU hat Irland aufgrund seines wirtschaftlichen Aufschwungs und der hohen Direktinvestitionen auf sich aufmerksam gemacht. Die Autorin untersucht, welche internen (Standortfaktoren) und externen Rahmenbedingungen (europäische Integration) eine erfolgreiche Anwerbung von Direktinvestitionen ermöglicht haben. Von besonderem Interesse ist, inwieweit andere Mitgliedsländer der EU die Strategie Irlands übernehmen können. Nach der Ermittlung eines theoretischen Analyserahmens wird dieser auf Irland angewendet. Dabei sind die Direktinvestitionszuflüsse durch die regionale Integration zu erklären, jedoch nur in Kombination mit den irischen Besonderheiten. Insbesondere die langfristige Ausrichtung der wirtschaftspolitischen Maßnahmen auf die MNU haben dazu beigetragen.
    Keywords: Ausländische ; Beispiel ; Direktinvestition ; Direktinvestitionen ; Europäische Integration ; Integration ; Irland ; Irland ; Köller ; MNU ; MOEL ; regionale ; Standortdeterminanten ; Wirtschaftsentwicklung ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPA Political science and theory ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCA Economic theory and philosophy ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management
    Language: German
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: artificial reefs ; offshore oil and gas platforms ; coastal infrastructure ; aquaculture facilities ; anthropogenic influences ; ecological restoration ; marine conservation ; rigs-to-reef ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RB Earth sciences::RBK Hydrology and the hydrosphere::RBKC Oceanography (seas and oceans)
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  • 37
    Publication Date: 2023-12-21
    Description: The non-classical HLA class I molecule HLA-G is different from classical HLA class I molecules because of the low polymorphism in the coding region, the fact that HLA-G primary transcript is alternatively spliced in seven isoforms, and the inhibitory action on immune cells. Although HLA-G is low polymorphic, variants in both promoter and 3’ un-translated region (UTR) of HLA-G locus regulate its expression. In healthy conditions, a basal level of HLA-G gene transcription is observed in most cells and tissues; however, translation into HLA-G protein is restricted to trophoblasts in the placenta, where it participates in promoting tolerance at the fetal-maternal interface. HLA-G is also expressed by thymic epitelial, cornea, mesenchymal stem cells, nail matrix, pancreatic beta cells, erythroid, and endothelial precursors. HLA-G can be neo-expressed in adult tissues in pathological conditions, and its expression has been documented autoimmune disorders, viral infections, and cancer. In the latter setting de novo HLA-G expression is associated with the capability of tumor cells to evade the immune control. In the last decade it has become evident that HLA-G expression on T cells and antigenpresenting cells confers to these cells tolerogenic properties. This Research Topic focused on i) summarizing updated clinical and immunological evidences that HLA-G expression is associate with beneficial or detrimental tolerance, ii) gathering new insights into the mechanisms governing the expression of HLA-G in healthy and pathological conditions, such as pre-eclampsia, and iii) examining the mechanisms underlying HLA-G mediated tolerance.
    Keywords: R5-920 ; RC581-607 ; Pregnancy ; Autoimmunity ; Immuno-modulation ; Pre-Eclampsia ; Infections ; Exosomes ; HLA-G ; polymorphisms ; tolerance ; Cancer ; bic Book Industry Communication::M Medicine
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  • 38
    Publication Date: 2024-03-29
    Description: In the year 2013, ‘selfie’ was named word of the year by Oxford Dictionaries in recognition of dramatic changes in frequency, prominence, and register of the term. This drastic increase in selfie-taking was spurred by two factors. The first was the advent of smartphones equipped with front cameras and preview screens that made it easy to compose a photographic self-portrait by a process of deliberately exploring one’s image, choosing a pose, and finally taking the picture. The second key change contributing to the rise of the selfie age was the increasing availability of internet connections. It is estimated that about 50% of the world population has access to the internet today (2018; https://www.internetworldstats.com). At the end of the past century, this percentage was a mere 1%. The growth of the internet infrastructure simultaneously spurred the development of social network applications such as Facebook, Twitter, Snapchat, and Instagram, providing accessible media for sharing photographs including photographic self-portraits. However, despite their tremendous reach and popularity, selfies have so far received relatively little attention by the scientific community, especially within psychology. Thus, we proposed a Frontiers in Psychology Research Topic to expand empirical and theoretical work on the massively popular, yet scientifically unexplored, phenomenon of the selfie. The articles published in this eBook offer a multifaceted insight into current scholarly work on this topic.
    Keywords: BF1-990 ; Q1-390 ; group selfies ; self-esteem ; Human Computer Interaction (HCI) ; self-presentation ; selfie ; viewing perspective ; perception bias ; smartphones ; social media ; internet ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 39
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-01
    Description: Kazimierz Moczarski (1907–1975) was a journalist, soldier, and political prisoner. His life exemplifies a Central European biography under Nazism and Comunism. The addictive and moving Civility in Uncivil Times reveals the story of a man who defended law and democracy all his life. Moczarski fought for it in the authoritarian Poland of the 1930s. During the Second World War, he partook in the resistance movement. After the war, he spent eleven years in a Stalinist prison, including nine months in one cell with the Nazi Jürgen Stroop, who commanded the brutal pacification of the Warsaw Ghetto. The communists imprisoned Moczarski’s wife. After release, he rebuilt the broken marriage, rejoined social life, and wrote a work about meeting Stroop. Translated into many languages, Conversations with the Executioner is a thorough study of totalitarianism.
    Keywords: anti-Semitism ; Battle ; Biography ; Civility ; Kazimierz ; Machcewicz ; Moczarski ; Moczarski's ; Polish ; political prisoner ; post-Stalinist thaw ; Prison ; prison letters ; Quiet ; Stalinism ; Stalinist ; terror ; Times ; Truth ; Uncivil ; Underground ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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  • 40
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Um eine Analyse der Bildlichkeit im Prosawerk Marlinskijs vornehmen zu können, bedarf es im Vorfeld einer Skizzierung dessen, was eine solche Untersuchung zu leisten imstande ist. Dem bildlichen Ausdruck als Interpretationseinheit, seinem Inhalt und seiner Stellung im Kontext soll das Hauptaugenmerk der vorliegenden Arbeit gelten. Denn die Art und Weise, wie Marlinskij bestimmte Sachverhalte neu und überraschend benennt, läßt Rückschlüsse auf sein Verhältnis zur Welt und seine persönliche Sicht der Dinge zu. Die durch den Autor vorgenommenen subjektiven Neuzuweisungen von Bezeichnungen und Begriffen lassen den Leser einen tiefen Einblick in die Gedankenwelt des Dichters tun und zu den verborgenen Ebenen seines dichterischen Werkes vorstoßen.
    Keywords: Becker ; Bestužev ; Bildfunktionen ; Bildlichkeit ; Erzählerprojektion ; Gefühlswelt der Gestalten ; Gestaltenprojektion ; Gestalthaftigkeit ; Marlinskijs ; Nekvedavičius ; Prosawerk ; Untersuchungen ; thema EDItEUR::D Biography, Literature and Literary studies
    Language: German
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    Frontiers Media SA
    Publication Date: 2024-03-31
    Description: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.
    Keywords: QP1-981 ; Q1-390 ; Vitamin D ; Immune System ; Genomics ; vitamin D receptor ; Physiology ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: resting-state fMRI ; fMRI denoising ; vascular modulation ; head motion ; arousal ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: COVID-19’s impacts revealed that teaching writing online was no longer merely an issue of convenience or economic necessity—it was critical to public health and equity concerns as well. Now higher education faces one of its greatest historical challenges, expanding online offerings to fully engage and support students around the world. Gathering together educators who teach writing at college and graduate levels using creative hybrid, blended, and online/remote/virtual modes, this book should be required reading for all teachers and administrators. The volume features those new to online teaching alongside experienced online writing teachers. Referencing the latest research in online teaching and writing, contributors share stories of crucial successes as well as unforeseen difficulties. Essays address compelling concerns such as engaging diversity and cultural inclusivity, social justice, as well as global learning in online writing courses; radically reshaping graduate seminars for online delivery; flipping classrooms to promote more successful writing instruction; fostering greater community within online writing classrooms; examining the problems and possibilities of Learning Management Systems for teaching writing; sustaining remote writing-centered archival research; avoiding Zoom fatigue in writing classes by using design thinking; utilizing expressive arts in online writing classes; mentoring doctoral students online; constructing meaningful approaches to online peer writing feedback; as well as making access and inclusivity central to online writing course design.
    Keywords: Courses ; COVID-19 ; Dunshea ; flipped and hybrid classrooms ; global outreach and online education ; Go Online! Reconfiguring Writing Courses for the New, Virtual World ; Gray ; Laura ; Laura Gray-Rosendale ; learning management systems ; Online ; online discussion/peer feedback ; online/remote teaching and technology ; Pandemic ; Philip ; Reconfiguring ; Rosendale ; social justice/ equity and diversity ; Steven ; Steven Rosendale ; teaching writing/composition online ; Virtual ; Writing ; Zoom/Collaborate ; thema EDItEUR::C Language and Linguistics::CJ Language teaching and learning::CJA Language teaching theory and methods
    Language: English
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-01
    Description: The book is a comparative case study of collective memory in two small communities situated on two Central-European borderlands. Despite different pre-war histories, Ukrainian Zhovkva (before 1939 Polish Żółkiew) and Polish Krzyż (before 1945 German Kreuz) were to share a common fate of many European localities, destroyed and rebuilt in a completely new shape. As a result of war, and post-war ethnic cleansing and displacement, they lost almost all of their pre-war inhabitants and were repopulated by new people. Based on more than 150 oral history interviews, the book describes the process of reconstruction of social microcosm, involving the reader in a journey through the lives of real people entangled in the dramatic historical events of the 20th century.
    Keywords: Collective Identity ; Deportation and resettlement ; Displaced ; Forgetting ; Galicji ; Holocaust and ethnic cleansing ; Kopernika ; Memories ; Mikołaja ; Naukowe ; Odzyskanych ; pamięć ; pamięci ; Poland ; Polish-Ukrainian conflict ; Politics of memory ; polskich ; Post ; Przesiedlenia ; przykładzie ; Remembering ; Second World War ; społecznej ; Studium ; Ukraine ; ukraińskiej ; Uniwersytetu ; Wydawnictwo ; Wylegala ; Ziem ; thema EDItEUR::N History and Archaeology::NH History
    Language: English
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-29
    Description: Seit über einem Jahrzehnt werden in Entwicklungs- und Schwellenländern Unternehmen des öffentlichen Sektors privatisiert. Als besonders problematisch gilt der Wassersektor auf Grund seiner ausgeprägten Monopoleigenschaften. Argentinien kann mit der Privatisierung der Wasserversorgung von Buenos Aires auf einen reichen Erfahrungsschatz verweisen. Dies nimmt der Autor zum Anlass, die Erfolge und Probleme der Privatisierung und Regulierung des argentinischen Wassersektors zu untersuchen. Ziel ist es, ausgehend von den argentinischen Erfahrungen einen Katalog von Handlungsregeln zu erarbeiten, der bei der Privatisierung öffentlicher Unternehmen in anderen Ländern beachtet werden sollte. Die Analyse erfolgt mittels des wirtschaftswissenschaftlichen Instrumentariums und den darauf aufbauenden normativen und positiven Regulierungsmodellen.
    Keywords: Aires ; Argentinas, Aguas ; Argentinien ; Argentinien ; Beispiel ; Buenos ; Buenos Aires ; England ; ETOSS ; Kommunaler Versorgungsbetrieb ; Menem, Carlos Saul ; Müller ; Privatisierung ; Privatisierung ; Regulierung ; Scheeßel ; Wales ; Wasse ; Wassersektors ; Wasserversorgung ; bic Book Industry Communication::J Society & social sciences::JP Politics & government ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCM Development economics & emerging economies ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCP Political economy ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCS Economic systems & structures ; thema EDItEUR::J Society and Social Sciences::JP Politics and government ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCM Development economics and emerging economies ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCP Political economy ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCS Economic systems and structures
    Language: German
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Postkoloniale Konstellationen lassen sich nicht (mehr) in das Eigene und das Andere, in das Originäre und das Nachgeahmte, in ein Hier und Dort auseinanderdividierenden. Sie sind geprägt von Verflechtungen, Hybri-disierungen und wechselseitigen Aneignungsprozessen. In diesem Band analysiert die Autorin Texte von Jurij Brězan, Irena Brežná, Mascha Dabić, Róža Domašcyna, Olga Grjasnowa, Barbi Marković, Olga Martynova und Aleksandar Tišma. Sie zeigt auf, dass alle Werke sich mit multiplen Zuge-hörigkeiten, Mehrsprachigkeit und Übersetzung auseinandersetzen. Die Texte dekonstruieren Grenzen sprachlicher und kultureller Zugehörigkeit, thematisieren aber auch Diskriminierung, Rassismus und Antisemitismus. Damit beschreiben sie mehrsprachige Welten jenseits von hegemonialer Einsprachigkeit.
    Keywords: Aleksandar Tišma ; Barbi Marković ; deutsche ; Einsprachigkeit ; Hitzke ; Jurij Brězan ; Mehrsprachigkeit ; Olga Grjasnowa ; Olga Martynova ; Postkoloniale Literatur ; Slavisch ; Sorbische Literatur ; Texte ; transkulturell ; Übersetzung ; Verflechtung ; thema EDItEUR::C Language and Linguistics::CF Linguistics ; thema EDItEUR::D Biography, Literature and Literary studies::DS Literature: history and criticism::DSB Literary studies: general
    Language: German
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    Springer Nature | Springer
    Publication Date: 2024-04-08
    Description: This book is open access under a CC BY 4.0 license. This book addresses the age-old problem of infinite regresses in epistemology. How can we ever come to know something if knowing requires having good reasons, and reasons can only be good if they are backed by good reasons in turn? The problem has puzzled philosophers ever since antiquity, giving rise to what is often called Agrippa's Trilemma. The current volume approaches the old problem in a provocative and thoroughly contemporary way. Taking seriously the idea that good reasons are typically probabilistic in character, it develops and defends a new solution that challenges venerable philosophical intuitions and explains why they were mistakenly held. Key to the new solution is the phenomenon of fading foundations, according to which distant reasons are less important than those that are nearby. The phenomenon takes the sting out of Agrippa's Trilemma; moreover, since the theory that describes it is general and abstract, it is readily applicable outside epistemology, notably to debates on infinite regresses in metaphysics. The book is a potential game-changer and a must for any advanced student or researcher in the field.
    Keywords: Epistemology ; Mathematical Logic and Foundations ; Statistical Theory and Methods ; History and Philosophical Foundations of Physics ; Operations Research/Decision Theory ; Philosophical Foundations of Physics and Astronomy ; Operations Research and Decision Theory ; Epistemic Justification ; Infinite Regress ; Regresses in Epistemology ; Regresses in Ethics ; Regresses in Metaphysics ; Regresses in Philosophy of Mind ; Open Access ; Philosophy: epistemology & theory of knowledge ; Mathematical foundations ; Mathematical logic ; Probability & statistics ; History of science ; Operational research ; Management decision making ; bic Book Industry Communication::H Humanities::HP Philosophy::HPK Philosophy: epistemology & theory of knowledge ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBC Mathematical foundations ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBT Probability & statistics ; bic Book Industry Communication::P Mathematics & science::PD Science: general issues::PDX History of science ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management::KJT Operational research ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTK Philosophy: epistemology and theory of knowledge ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBC Mathematical foundations ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBT Probability and statistics ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDX History of science ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJT Operational research
    Language: English
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    Frontiers Media SA
    Publication Date: 2022-01-31
    Description: This research topic is focused on recent advances in our understanding of effects of mechanical loading on the skeleton, and research methods used in addressing these. Though it is well established that mechanical loading provides an essential stimulus for skeletal growth and maintenance, there have been major advances recently in terms of our understanding of the molecular pathways involved, which are thought to provide novel drug targets for treating osteoporosis. The articles included in this topic encompass the full spectrum of laboratory and clinical research, and range from review articles, editorials, hypothesis papers and original research articles. Together, they demonstrate how mechanical loading underpins many aspects of bone biology, including the pathogenesis and treatment of osteoporosis and other clinical disorders associated with skeletal fragility.
    Keywords: RC648-665 ; R5-920 ; mechanical loading ; bone architecture ; accelerometers ; osteoblast ; osteoporosis ; osteoclast ; fractures ; distraction osteogenesis
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Glial cells are no longer considered passive bystanders in neuronal brain circuits. Not only are they required for housekeeping and brain metabolism, they are active participants in regulating the physiological function and plasticity of brain circuits and the online control of behavior both in invertebrate and vertebrate model systems. In invertebrates, glial cells are essential for normal function of sensory organs (C. elegans) and necessary for the circadian regulation of locomotor activity (D. melanogaster). In the mamallian brain, astrocytes are implicated in the regulation of cortical brain rhythms and sleep homeostasis. Disruption of AMPA receptor function in a subset of glial cell types in mice shows behavioral deficits. Furthermore, genetic disruption of glial cell function can directly control behavioral output. Regulation of ionic gradients by glia can underlie bistability of neurons and can modulate the fidelity of synaptic transmission. Grafting of human glial progenitor cells in mouse forebrain results in human glial chimeric mice with enhanced plasticity and improved behavioral performance, suggesting that astrocytes have evolved to cope with information processing in more complex brains. Taken together, current evidence is strongly suggestive that glial cells are essential contributors to information processing in the brain. This Research Topic compiles recent research that shows how the molecular mechanisms underlying glial cell function can be dissected, reviews their impact on plasticity and behavior across species and presents novel approaches to further probe their function.
    Keywords: RC321-571 ; Q1-390 ; Cerebellum ; C. elegans ; Astrocytes ; DREADD ; Cortex ; plasticity ; Gq ; Behavior ; glia ; Hippocampus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Thy-1 ; CD90 ; Signal Transduction ; cell-cell interaction ; Cell-matrix interaction ; Scaffold ; Nanodomains ; integrin ; Mechanotransduction ; Cancer ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: export ; secretion ; pathogens ; toxins ; macromolecular machineries ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2023-12-21
    Description: Lymphocytes constantly survey the lymph nodes in search for potential infection by a pathogen. They enter the afferent lymphatic vessel that serves as a conduit to transport the motile lymphocytes to the draining lymph node. Lymphatic vessels (LVs) are present in most vascularized tissues. They are traditionally regarded as passive conduits for soluble antigens and leukocytes. Afferent LVs begin as blind ended capillaries, which give rise to collecting vessels that merge and connect with draining lymph nodes (dLNs). Initial lymphatic capillaries are composed of Lymphatic Endothelial Cells (LECs) connected by discontinuous cell junctions, which join to form larger collecting lymphatic vessels, and ultimately feed into the LN subcapsular sinus. Within the LN, LECs are localized to the subcapsular, cortical, and medullary sinuses, where they interact with incoming and exiting leukocytes. LECs, and in general LN stromal cells, have emerged in the recent years as active players in the immune response. In support to this,studies have shown that the immune response generated during inflammation and under pathologic conditions is accompanied by modeling of the LVs and generation of new lymphatics, a process known as lymphangiogenesis. These facts strongly suggest that LECs and stromal LN cells in general, are not inert players but rather are part of the immune response by organizing immune cells movement, exchanging information and supplying survival factors. The purpose of this research topic is to review the role of the LECs during immune homeostasis and cancer. Considering the critical role of lymphangiogenesis in many pathologies like chronic and acute inflammation, autoimmunity, wound healing, graft rejection, and tumor metastasis, it is important to understand the molecular mechanisms that govern the cross talks between the LECs and immune cells during homeostasis and inflammation.
    Keywords: R5-920 ; RC581-607 ; Liver Injury ; Lymphatic Vessels ; Lymphatic Vasculature ; Tumor Microenvironment ; PD-L1 ; Antigen Presenting Cells ; Lymphatic Endothelial Cells ; T cell trafficking ; T cells ; bic Book Industry Communication::M Medicine
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Heart Rate ; Heart rate variability ; Autonomic Nervous System ; infants ; Children ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-29
    Description: Die Studie zum Fremdsprachenunterricht in deutschen Grundschulen bietet einen Überblick über Bundesländergrenzen hinweg in eine heterogene Bildungslandschaft, die von erheblichen curricularen Unterschieden und Widersprüchen geprägt ist. Neben dieser Bestandsaufnahme zeigen die Autoren auf, welche bildungspolitischen und fachdidaktischen Ausgestaltungen Fachleute aus Hochschulen, Landesinstituten und Schulen als sinnvoll und wünschenswert erachten. Ihr Meinungsbild erlaubt es, bundesländerübergreifende Konzepte für die qualitative Weiterentwicklung des frühen Fremdsprachenunterrichts zu entwickeln, daraus resultierende Implikationen für Lehreraus- und Fortbildung zu beleuchten und so letztlich eine Basis für nationale Mindeststandards für den Fremdsprachenunterricht in der Grundschule zu bieten.
    Keywords: Languages ; Elementary School ; Foreign Language Learning ; Germany ; Bundesländer ; education policy ; Teacher Training ; bic Book Industry Communication::J Society & social sciences::JN Education::JNT Teaching skills & techniques ; thema EDItEUR::J Society and Social Sciences::JN Education::JNT Teaching skills and techniques
    Language: German
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    Springer Nature | Springer
    Publication Date: 2024-04-05
    Description: This open access textbook aims at providing detailed explanations on how to design and construct image analysis workflows to successfully conduct bioimage analysis. Addressing the main challenges in image data analysis, where acquisition by powerful imaging devices results in very large amounts of collected image data, the book discusses techniques relying on batch and GPU programming, as well as on powerful deep learning-based algorithms. In addition, downstream data processing techniques are introduced, such as Python libraries for data organization, plotting, and visualizations. Finally, by studying the way individual unique ideas are implemented in the workflows, readers are carefully guided through how the parameters driving biological systems are revealed by analyzing image data. These studies include segmentation of plant tissue epidermis, analysis of the spatial pattern of the eye development in fruit flies, and the analysis of collective cell migration dynamics. The presented content extends the Bioimage Data Analysis Workflows textbook (Miura, Sladoje, 2020), published in this same series, with new contributions and advanced material, while preserving the well-appreciated pedagogical approach adopted and promoted during the training schools for bioimage analysis organized within NEUBIAS – the Network of European Bioimage Analysts. This textbook is intended for advanced students in various fields of the life sciences and biomedicine, as well as staff scientists and faculty members who conduct regular quantitative analyses of microscopy images.
    Keywords: Analyzing Image Data in Biology ; Building a Bioimage Analysis Workflow ; Computational Analysis ; Chosing the Correct Components for Given Biological Questions ; Data Handling and Plotting ; Deep Learning ; Fast Computation ; GPU-Acceleration ; Handling Biological data ; Machine Learning ; Phyton ; Processing Language ; Understanding Bioimage Analysis Software ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: NMDAR = N-methyl-d-aspartate receptor ; Enzymes - metabolism ; enzyme drug target ; d-serine ; L-serine ; thema EDItEUR::P Mathematics and Science::PD Science: general issues
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    Frontiers Media SA
    Publication Date: 2024-03-30
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: biobank ; samples ; data ; biobank network ; BBMRI
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-30
    Description: A company operating various sales channels, e.g. the Internet and a traditional shop, inevitably faces a tricky coordination problem. As prevalent approaches often do not lead to a satisfying solution, the author suggests a normative model to offer directions for the optimal channel coordination. The model is based on stochastic purchase and switching probabilities, given certain conditions like prices and supportive marketing activities (like delivery time or shop environment). A company can fit its consumer base to the model and simulate various effects on its earnings by altering prices or marketing activities. The model is a market-based playground to develop new holistic strategies for a multichannel company without affecting the market.
    Keywords: Consumer Behaviour ; E-Commerce ; Gruber ; Management ; Model ; Multichannel ; Normative ; Optimality ; Pricing ; Stochastic Modelling ; Towards ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas::KJMV5 Production and quality control management
    Language: English
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: The present study would like to close at least some of the previous gaps in a concise overview, which is why also previously overlooked seemingly marginal areas of the literature of the belles lettres and the hymn. It confines itself to the presentation of the direct journalistic effects of the literature exchange in the form of translations and literary criticism, thus for example dispensing with the inclusion of correspondence already printed in part anyway.
    Description: Die vorliegende Untersuchung möchte nun in einem wenngleich gedrängten Überblick zumindest einige der bisherigen Lücken schließen, weshalb auch bisher weniger beachtete scheinbare Randgebiete der schöngeistigen Literatur und das Kirchenlied. Sie beschränkt sich dabei auf die Darstellung der unmittelbaren publizistischen Auswirkungen des Literaturaustausches in Form von Übersetzungen und Literaturkritik, verzichtet also etwa auf die Einbeziehung von ohnehin nur in Teilen gedruckt vorliegenden Korrespondenzen.
    Keywords: Belletristik im 18. Jahrhundert ; das katholische Kirchenlied ; das protestantische Kirchenlied ; Deutsch ; deutsch-slavische Literaturbeziehung ; Drews ; Jahrhun ; Jahrhundert ; Jugendliteratur ; Literaturbeziehungen ; slavische ; thema EDItEUR::D Biography, Literature and Literary studies
    Language: German
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-04-01
    Description: The different theoretical notions and practices of the relations between the state and religious communities in early modern Europe constitute one of the most interesting problems in historiography. Moving away from a simple «toleration» versus «non-toleration» dichotomy, the author sets out to analyse the inter-confessional relations in selected European territories in a «longue duree» perspective, between Reformation and Enlightenment. Outlining the relations between the state and the different Churches (confessions) in the Polish-Lithuanian Commonwealth, the Holy Roman Empire of Germany, and the Northern Netherlands serves to highlight the specificity of Northern Netherlands serves to highlight the specificity of «free» (non-absolutist) composite states, where the particularly complex process of defining the raison d’etat determined the level of religious toleration that was politically feasible and socially acceptable.
    Keywords: Church ; Church-state relations ; Confessional ; Denominational relations ; Enlightenment ; Germany ; Humanist and political theory ; Kriegseisen ; Lithuania ; Netherlands ; Poland ; Protestant and Catholic reformers ; Reform ; Reformation ; Relations ; State ; thema EDItEUR::N History and Archaeology ; thema EDItEUR::3 Time period qualifiers::3M c 1500 onwards to present day ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: English
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  • 61
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Microbial ; activity ; extracellular enzyme ; marine ; freshwater ; Metabolic potential ; function ; metabolic ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: The work consists of two parts. The first part deals exclusively with the aspect properties of Russian prefigured verbs. A perfective analysis for Russian is proposed, which allows to grasp the semantic differences between imperfective Simplizia and its derivative derivatives in semantic terms. The second part of the thesis is an application of the proposed perfective analysis to Russian pere-prefixed verbs. It is shown that the meaning variants of pere-prefixed verbs in Russian can be derived from a general prefix scheme and the semantics of the stem verb.
    Description: Die Arbeit besteht aus zwei Teilen. Der erste Teil befaßt sich ausschließlich mit den aspektuellen Eigenschaften russischer präfigierter Verben. Es wird eine Perfektivanalyse für das Russische vorgeschlagen, die es ermöglicht, die semantischen Unterschiede zwischen imperfektiven Simplizia und ihren perfektiven Derivata in semantischen Termen zu erfassen. Der zweite Teil der Arbeit stellt eine Anwendung der vorgeschlagenen Perfektivanalyse auf russische pere-präfigierte Verben dar. Es wird gezeigt, daß die Bedeutungsvarianten pere-präfigierter Verben im Russischen aus einem allgemeinen Präfixschema und der Semantik des Stammverbs abgeleitet werden können.
    Keywords: Analyse ; Demjjanow ; Eine ; Fallstudie ; imperfektives Simplizia ; pere ; Perfektivaxiome ; Perfektivierung im Lexikon ; Perfektivierungspräfigierung ; Perfektiv-Imperfektivtest ; Russischen ; semantische ; Verbpräfigierung ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-30
    Description: Wie wirken sich politisch-institutionelle Rahmenbedingungen auf die ökonomische Leistungsfähigkeit einer Gesellschaft aus? Dieser Frage wird hier aus dem Blickwinkel der Theorie der politischen Ökonomie nachgegangen. Zunächst werden hierfür die theoretischen Grundlagen skizziert. Auf dieser Basis wird der Schwerpunkt der sich anschließenden Analyse auf die durch politische Systeme definierten kollektiven Entscheidungsverfahren und deren Auswirkungen u. a. auf die Besteuerung, die Bereitstellung öffentlicher Güter und Rent-Seeking gelegt. Hierzu werden etablierte Modelle dargestellt und deren Gemeinsamkeiten aufgezeigt. Abschließend erfolgt eine Überprüfung der theoretischen Schlussfolgerungen anhand des empirischen Forschungsstandes.
    Keywords: Entscheidungsverfahren ; Geruschkat ; Ökonomie ; Politische Systeme ; politischer ; Systeme ; Theorie der politischen Ökonomie ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCA Economic theory and philosophy
    Language: German
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: precise genome editing ; CRISPR ; HDR efficiency ; biallelic HDR targeting ; off-target effect ; animal model ; base editing ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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  • 65
    Publication Date: 2024-04-05
    Description: In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and neural dynamics in humans. A growing body of evidence indicates that the neural dynamics (e.g., oscillations, synchrony) are important in mediating information processing and networking for various functions in the human brain. Most of previous studies on human brain dynamics, however, show correlative relationships between brain functions and patterns of neural dynamics measured by imaging methods such as electroencephalography (EEG), magnetoencephalography (MEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). In contrast, manipulative approaches by non-invasive brain stimulation (NIBS) have been developed and extensively used. These approaches include transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) such as transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), and random noise stimulation (tRNS), which can directly manipulate neural dynamics in the intact human brain. Although the neural-correlate approach is a strong tool, we think that manipulative approaches have far greater potential to show causal roles of neural dynamics in human brain functions. There have been technical challenges with using manipulative methods together with imaging methods. However, thanks to recent technical developments, it has become possible to use combined methods such as TMS–EEG coregistration. We can now directly measure and manipulate neural dynamics and analyze functional consequences to show causal roles of neural dynamics in various brain functions. Moreover, these combined methods can probe brain excitability, plasticity and cortical networking associated with information processing in the intact human brain. The contributors to this EBook have succeeded in showcasing cutting-edge studies and demonstrate the huge impact of their approaches on many areas in human neuroscience and clinical applications.
    Keywords: RC321-571 ; Q1-390 ; non-invasive brain stimulation NIBS ; TMS-EEG ; Transcranial magnetic stimulation TMS ; transcranial electric stimulation tES ; Coregistration ; Near-infrared spectroscopy NIRS ; Functional magnetic resonance imaging fMRI ; transcranial direct current stimulation tDCS ; transcranial alternating current stimulation tACS ; transcranial random noise stimulation tRNS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 66
    Publication Date: 2024-04-05
    Description: Bálint’s syndrome is named after the Hungarian physician who first reported a remarkable case of a man with complex visuospatial deficits following bilateral lesions within parietal and occipital cortex (Bálint, 1909). The syndrome has three primary symptoms: simultanagnosia (impaired spatial awareness of more than one object at time), optic ataxia (misreaching to visual targets) and ocular apraxia (described by Bálint as “psychic paralysis of gaze”). Balint’s patients not only cannot perceive more than one object at time and therefore show poor comprehension of multi-object visual scenes i.e. poor detection of all the objects present and difficulty in grasping the relationship between them; in addition they typically fail to reach towards location of the single object, which they can perceive. The deficit of the allocation of spatial attention in Balint’s syndrome has been linked to a problem in feature binding which results in illusory conjunctions. Patients with Balint’s syndrome also show deficits in global processing i.e. when integration of multiple local elements into global compound shapes is required. Consequently, Balint’s syndrome provides a unique opportunity to study the nature and neuroanatomy of human visuospatial processing, in particular multi-level object representation, spatial awareness and the distribution of visual attention. The studies collected here cover both the anatomical and the cognitive mechanisms of the different symptoms associated with the syndrome. Furthermore, the dissociations between the components of Bálints’ syndrome, in particular simultanagnosia and optic ataxia, can also co-occur with visual neglect and extinction and the different combinations of reported lesions raises a question about the status of the syndrome and whether it should be merely treated as a historical compilation of symptoms which may or may not coexist cohesively. This interesting argument is raised here.
    Keywords: RC321-571 ; Q1-390 ; posterior cortical atrophy ; Balints syndrome ; optic ataxia ; Posterior parietal cortex ; simultanagnosia ; ocular apraxia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Springer Nature | Springer
    Publication Date: 2021-02-10
    Description: This open access book provides anthropological insights into the arduous yet rewarding journeys involved in selected TESOL teachers’ pedagogical transition to teaching English for Academic Purposes (EAP) at universities in Shanghai, the largest metropolitan area in China. Applying a unique combination of ethnography and phenomenology, the book offers innovative new perspectives on teacher education research. Drawing on the latest language education theory, it outlines a practitioner-friendly approach to EAP literacy. Teacher readers will especially benefit from the case studies presented here, which provide role models for teacher change in educational reform, as well as advice on their academic careers. In addition to addressing a timely and important research gap on EAP teachers in non-Western countries, the book is the ideal choice for readers interested in an update on English education in China.
    Keywords: Philosophy of Education ; Language Education ; Teaching and Teacher Education ; Social Anthropology ; EAP Teacher Education ; EAP Teaching ; University English Teaching ; China Higher Education ; Teacher Change ; Open Access ; Philosophy & theory of education ; Language: reference & general ; Teacher training ; Social & cultural anthropology ; bic Book Industry Communication::J Society & social sciences::JN Education::JNA Philosophy & theory of education ; bic Book Industry Communication::C Language::CB Language: reference & general ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education::JNMT Teacher training ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHM Anthropology::JHMC Social & cultural anthropology, ethnography
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  • 68
    Publication Date: 2024-04-05
    Description: The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.
    Keywords: RC321-571 ; Q1-390 ; Glaucoma ; Visceral Pain ; Calcium ; membrane guanylate cyclase ; ANF-RGC ; Gene Therapy ; Cyclic GMP ; synaptic plasticity ; trafficking ; ROS-GC ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Microbial communities ; Pollutants ; Environmental risk assessment ; Bioindication ; Biodegradation ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFM Medical microbiology and virology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: 〈P〉Vasilij Kirillovič Trediakovskij: dieser Name allein schreckt die meisten Leser ab. Daß dieser Gelehrte neben Lomonosov zu den Gründern der neueren russischen Literatur gehört, wird selten gebührend erwähnt. Diese Arbeit soll von ihm handeln, und besonders von einem Werk, das beinahe nicht zur Kenntnis genommen wird. Es soll eine gänzlich in Vergessenheit geratene Begegnung wieder ans Licht kommen: die Begegnung zwischen dem Autor Trediakovskij, dessen Rolle in der Literaturgeschichte unterschätzt wird, und einem Roman John Barclays, der "Argenis", dem in ganz Europa populärsten Roman des 17. Jahrhunderts. Hier wird eine Übersetzung Gegenstand sein; dennoch handelt es sich hier keineswegs um eine übersetzungskritische Arbeit. 〈/P〉
    Keywords: Argenida ; Carrier ; keines ; Linguistik ; Literaturgeschichte ; Russland ; Slavische Sprachwissenschaft ; Trediakovskij ; Übersetzung ; Vorbild ; wurde ; thema EDItEUR::C Language and Linguistics
    Language: German
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    Springer Nature | Springer
    Publication Date: 2024-04-04
    Description: This open access book introduces the modern tontine and its applications in retirement and decumulation. Personal financial management in the later stages of life presents unique challenges, and renowned retirement planning expert Dr. Milevsky proposes the modern tontine as a solution. With the goal of guiding professionals and retirees in more efficient decumulation, the book demonstrates how to build a modern tontine. It is technically oriented, employing a cookbook format, featuring R code, and examining retirement planning through a statistical lens. This how-to guide, which is a sequel to his 2020 book “Retirement Income Recipes in R”, will be invaluable for retirement planning professionals and advisors, as well as for PhD scholars in retirement planning, quantitative finance, and related fields. This book is open access.
    Keywords: tontine ; risk management ; retirement ; decumulation ; insurance ; Business Analytics ; Mathematical Finance ; Statistical Finance ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBT Probability and statistics ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBW Applied mathematics
    Language: English
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Alzheimer's disease ; Neurodegeneration ; Peptides ; cognitive ; model ; Parkinson's disease ; database ; transgenic ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: 〈P〉In der Reihe 〈I〉Slavistische Beiträge〈/I〉 werden vor allem slavistische Dissertationen des deutschsprachigen Raums sowie vereinzelt auch amerikanische, englische und russische publiziert. Darüber hinaus stellt die Reihe ein Forum für Sammelbände und Monographien etablierter Wissenschafter/innen dar.〈/P〉
    Keywords: Funktion ; historicum ; Linguistik ; Panzer ; Philologie ; Praesens ; Russischen ; Russland ; Slavische Sprachwissenschaft ; Sprachwissenschaft ; Verbalaspekts ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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  • 74
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Sport ; performance ; physiology ; kinesiology ; biomechanics ; health ; exercise ; physical activity ; athletes ; training ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::S Sports and Active outdoor recreation ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKW Sports injuries and medicine
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-29
    Description: Die Unterstützung der Innovationstätigkeit von Unternehmen durch staatliche Förderung stellt ein populäres Instrument der Politik dar. Diese Arbeit untersucht unter Anwendung von Ansätzen der Neuen Institutionenökonomik und Entrepreneurship-Theorie die Ausgestaltung von Innovationsförderung am Beispiel des Niedersächsischen Innovationsförderprogramms und die von diesem Programm ausgehende Wirkung auf die beteiligten Akteure. Daran schließt sich die Darstellung der Ergebnisse einer Unternehmensbefragung an, in welcher die theoretischen und empirischen Erkenntnisse verknüpft werden. Im Mittelpunkt steht dabei die Fragestellung, inwiefern sich Unternehmen, die Innovationsfördermittel erhalten haben, von nicht geförderten Unternehmen unterscheiden.
    Keywords: Analyse ; Beispiel ; Betrachtung ; Eine ; empirische ; Entrepreneurship ; Innovationsförderung ; Institutionenökonomische ; Mertins ; Neue Institutionenökonomik ; Niedersachsens ; theoretische ; Unternehmer ; Wirtschaftspolitik ; bic Book Industry Communication::J Society & social sciences::JP Politics & government ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCK Behavioural economics ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCP Political economy ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCS Economic systems & structures ; bic Book Industry Communication::K Economics, finance, business & management::KJ Business & management ; thema EDItEUR::J Society and Social Sciences::JP Politics and government ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCK Behavioural economics ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCP Political economy ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCS Economic systems and structures ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management
    Language: German
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  • 76
    Publication Date: 2024-04-05
    Description: In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system.
    Keywords: RC321-571 ; Q1-390 ; Nervous System ; Ion Channels ; Interactome ; cellular signaling ; Protein complexes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: The series Lectures and Treatises on Slavic Studies, which has been published since 1980, offers opportunities for publication, especially for smaller monographs, which, in terms of their scope, are located between the journal article and the large book. It will cover topics from the whole area of ​​Slavic languages, literatures and cultures as well as their interrelations. In addition to investigations, bibliographies, research reports and editions are published. The authors of the previous volumes come from America, Canada, Germany, Finland, Poland, Russia, Switzerland, Slovenia, the Czech Republic and Hungary.
    Description: Die seit 1980 erscheinende Reihe Vorträge und Abhandlungen zur Slavistik bietet Publikationsmöglichkeiten vor allem für kleinere Monographien, die ihrem Umfang nach zwischen Zeitschriftenbeitrag und großem Buch anzusiedeln sind. Aufgenommen werden Themen aus dem Gesamtbereich der slavischen Sprachen, Literaturen und Kulturen sowie ihrer Wechselbeziehungen. Neben Untersuchungen werden auch Bibliographien, Forschungsberichte und Editionen veröffentlicht. Die Autoren und Autorinnen der bisherigen Bände kommen aus Amerika, Kanada, Deutschland, Finnland, Polen, Rußland, Schweiz, Slowenien, Tschechische Republik und Ungarn.
    Keywords: 1885 ; 1898 ; Bondarev ; Briefe ; Donskov ; Erinnerungen ; Literaturwissenschaft ; Perepiska ; Russland ; Tagebücher ; Tolstoj ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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    Frontiers Media SA
    Publication Date: 2024-04-04
    Description: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
    Keywords: Brainstem monoamine neurons ; locus coeruleus ; emotion ; pain ; morphometry ; amphetamine derivatives ; sleep ; gaze ; trigeminal nerve ; microglia. ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 79
    Publication Date: 2024-04-05
    Description: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
    Keywords: QH426-470 ; Q1-390 ; Regional heritability ; prostate cancer ; infectious diseases ; MCMC ; combining studies screening ; conditional-logistic linkage ; Informatics ; autism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Die Zeitschrift Bibliothek und Medien (vormals ABDOS-Mitteilungen) ist das einzige Periodikum, das sich speziell an Osteuropa-Bibliothekarinnen und -Bibliothekare in Europa und den USA wie auch an solche in Ost-, Ostmittel- und Südosteuropa wendet. Sie versammelt ausgewählte Beiträge, Tagungs- (Berichte) und Miszellen aus dem Arbeitsgebiet der ABDOS-Mitglieder und Mitgliedsorganisationen. Besonderer Wert wird auf den Rezensionsteil gelegt. Die Redaktion nimmt Texte in deutscher, englischer und russischer Sprache entgegen.
    Keywords: Slavic languages ; thema EDItEUR::C Language and Linguistics::CJ Language teaching and learning
    Language: German
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  • 81
    Publication Date: 2024-04-14
    Description: This open access book provides a comprehensive treatment of recent developments in kernel-based identification that are of interest to anyone engaged in learning dynamic systems from data. The reader is led step by step into understanding of a novel paradigm that leverages the power of machine learning without losing sight of the system-theoretical principles of black-box identification. The authors’ reformulation of the identification problem in the light of regularization theory not only offers new insight on classical questions, but paves the way to new and powerful algorithms for a variety of linear and nonlinear problems. Regression methods such as regularization networks and support vector machines are the basis of techniques that extend the function-estimation problem to the estimation of dynamic models. Many examples, also from real-world applications, illustrate the comparative advantages of the new nonparametric approach with respect to classic parametric prediction error methods. The challenges it addresses lie at the intersection of several disciplines so Regularized System Identification will be of interest to a variety of researchers and practitioners in the areas of control systems, machine learning, statistics, and data science. This is an open access book.
    Keywords: System Identification ; Machine Learning ; Linear Dynamical Systems ; Nonlinear Dynamical Systems ; Kernel-based Regularization ; Bayesian Interpretation of Regularization ; Gaussian Processes ; Reproducing Kernel Hilbert Spaces ; Estimation Theory ; Support Vector Machines ; Regularization Networks ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence::UYQM Machine learning ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TJ Electronics and communications engineering::TJF Electronics engineering::TJFM Automatic control engineering ; thema EDItEUR::P Mathematics and Science::PH Physics::PHS Statistical physics ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBT Probability and statistics::PBTB Bayesian inference ; thema EDItEUR::P Mathematics and Science::PB Mathematics::PBT Probability and statistics ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general::GPF Information theory::GPFC Cybernetics and systems theory
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  • 82
    Publication Date: 2023-12-21
    Description: It is long known that many cells can shed extracellular vesicles, small membrane-enclosed cell fragments. Although the existence of extracellular vesicles has been recognized for many years, researchers are only beginning to understand their physiologic significance. Several recent studies have demonstrated that extracellular vesicles released from cells serve as a mode of cellular communication. They can carry diverse molecular payload (e.g. nucleic acids, bioactive lipids and proteins) to distal organs and recipient cells. Extracellular vesicles can be classified into three major groups: exosomes, microvesicles, and apoptotic bodies. All these types of extracellular vesicles can be found in a variety of biologic specimen and their numbers, distribution and composition may serve as biomarkers for various disorders, including cardiovascular disease. Although extracellular vesicle-mediated processes are currently best characterized in the fields of cancer biology and neurobiology, evidence is accumulating that extracellular vesicles play a key role in the pathophysiology of diabetes, thrombosis, inflammation and cardiovascular calcification. In this Research Topic, we invited review and methodological articles that advance our understanding of extracellular vesicle-related processes in vascular biology.
    Keywords: R5-920 ; Angiogenesis ; Atherosclerosis ; Extracellular vesicles ; Calcification ; Biomarkers ; Cardiovascular disease ; Inflammation ; Exosomes ; Platelets ; Heart valve ; bic Book Industry Communication::M Medicine
    Language: English
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  • 83
    Publication Date: 2022-01-31
    Description: This eBook presents illustrative examples of genetic chaperonopathies affecting primarily nerves and muscles and discusses molecular mechanisms and treatment targeting chaperones, i.e., chaperonotherapy.
    Keywords: Q1-390 ; small-Hsp ; Hsp60/CCT/BBS ; Indirect/Secondary Chaperonopathies ; Genetic Chaperonopathies ; Hsp40/DnaJ ; chaperonotherapy
    Language: English
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  • 84
    Publication Date: 2024-04-05
    Description: Virus-caused asthma, we now call a phenotype of asthma. Regardless of the significance and popularity of this disease, the etiology of the virus-induced asthma have not well understood. In addition, a few effective vaccines have been applied to prevent respiratory virus infection. To solve the issues, it is essential to clarify and delineate both aspects of the virus and host defense systems including acute/chronic inflammation and airway tissue remodeling. To deeply review and discuss pathophysiology and epidemiology of virus-induced asthma, this topics includes new findings of the host immunity, pathology, epidemiology, and virology of asthma/chronic obstructive pulmonary disease (COPD). We believe that these works are well summarized and informative to glimpse the field of virus- associated asthma and COPD, and may help understanding the basic and clinical aspects of the diseases.
    Keywords: QR1-502 ; QK1-989 ; Q1-390 ; virus-induced asthma ; Pathology ; respiratory virus ; human immunity ; Epidemiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 85
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Vorliegende Arbeit, die 1959 der Philosophischen Fakultät der Universität München als Dissertation eingereicht wurde, versucht erstmals in deutscher Sprache einen umfassenden Überblick über das Schaffen des weißruthenischen Nationaldichters Janka Kupała zu geben. Um den Nachweis zu führen, wie tief Kupałas dichterisches Werk in seinem Volkstum verwurzelt ist, wurde auf die Darstellung der volkskundlichen und volkstümlichen Elemente in seinem Werk besonderer Nachdruck gelegt.
    Keywords: Ethnographie ; Folkloristik ; Janka ; Kulturwissenschaft ; Kupała ; Moskalik ; Sänger ; Slavische Sprachwissenschaft ; Volkstums ; Weißrussland ; weissruthenischen ; thema EDItEUR::D Biography, Literature and Literary studies
    Language: German
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  • 86
    Publication Date: 2023-12-21
    Description: Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is widely used in the treatment of haematological malignancies as a form of immunotherapy acting through a graft-versus-leukemia (GvL) reaction. This curative allogeneic response can be associated with severe drawbacks, such as frequent and severe graft-versus-host disease (GvHD) and a long-lasting immunodeficiency, especially now with the development of innovative strategies such as umbilical cord blood transplantation or transplants from haplo-identical family donors (Haplo-HSCT). In the long-term follow-up of these patients, severe post-transplant infections, relapse or secondary malignancies may be directly related to persistent immune defects.Reconstitution of the different lymphocyte populations (B, T, NK, NKT) and antigen presenting cells of myeloid origin (monocytes, macrophages and dendritic cells) should be considered not only quantitatively but especially qualitatively, in terms of functional subsets. Immune deficiency leading to an increased susceptibility to infections lasts for more than a year. Although infections that occur in the first month mostly result from a deficiency in both granulocytes and mononuclear cells (MNC), later post-engraftment infections are due to a deficiency in MNC subsets, primarily CD4 T-cells and B-cells. T-cell reconstitution has been extensively studied because of the central role of T-cells in mediating both GvHD, evidenced by the reduced incidence of this complication following T-Cell depletion, and a GvL effect as shown by DLI. In the recent years there has been renewed interest in the role of NK-cells, especially in the context of Haplo-HSCT, and in B-cell reconstitution.This Frontiers Research Topic will provide state of the art knowledge of the mechanisms of immune reconstitution in an allogeneic environment, in order to improve monitoring and therapeutic intervention in allo-HSCT patients.
    Keywords: R5-920 ; RC581-607 ; cell therapy ; Immune reconstitution ; Haplo-SCT ; HSCT ; Thymic function ; bic Book Industry Communication::M Medicine
    Language: English
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  • 87
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    Springer Nature | Springer
    Publication Date: 2024-04-14
    Description: This open access two-volume set constitutes the proceedings of the 26th International Conference on Tools and Algorithms for the Construction and Analysis of Systems, TACAS 2020, which took place in Dublin, Ireland, in April 2020, and was held as Part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2020. The total of 60 regular papers presented in these volumes was carefully reviewed and selected from 155 submissions. The papers are organized in topical sections as follows: Part I: Program verification; SAT and SMT; Timed and Dynamical Systems; Verifying Concurrent Systems; Probabilistic Systems; Model Checking and Reachability; and Timed and Probabilistic Systems. Part II: Bisimulation; Verification and Efficiency; Logic and Proof; Tools and Case Studies; Games and Automata; and SV-COMP 2020.
    Keywords: Software Engineering/Programming and Operating Systems ; Special Purpose and Application-Based Systems ; Computer System Implementation ; Control Structures and Microprogramming ; Mathematics of Computing ; open access ; specification and verification techniques ; software and hardware verification ; SAT and SMT solving ; theorem proving ; model checking ; static and dynamic program analysis ; testing ; system construction and transformation techniques ; tool environments and tool architectures ; abstraction techniques for modeling and verification ; compositional and refinement-based methodologies ; mathematics ; software engineering ; software design ; architecting ; software architecture ; embedded systems ; automata theory ; linguistics ; Software Engineering ; Operating systems ; Expert systems / knowledge-based systems ; Systems analysis & design ; Algorithms & data structures ; Mathematical theory of computation ; Maths for computer scientists ; thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMZ Software Engineering ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence::UYQE Expert systems / knowledge-based systems ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYD Systems analysis and design ; thema EDItEUR::U Computing and Information Technology::UM Computer programming / software engineering::UMB Algorithms and data structures ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYA Mathematical theory of computation
    Language: English
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  • 88
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Transfer cells are anatomically specialized cells optimized to support high levels of nutrient transport in plants. These cells trans-differentiate from existing cell types by developing extensive and localized wall ingrowth labyrinths to amplify plasma membrane surface area which in turn supports high densities of membrane transporters. Unsurprisingly, therefore, transfer cells are found at key anatomical sites for nutrient acquisition, distribution and exchange. Transfer cells are involved in delivery of nutrients between generations and in the development of reproductive organs and also facilitate the exchange of nutrients that characterize symbiotic associations. Transfer cells occur across all taxonomic groups in higher plants and also in algae and fungi. Deposition of wall ingrowth-like structures are also seen in “syncytia” and “giant cells” which function as feeding sites for cyst and root-knot nematodes, respectively, following their infection of roots. Consequently, the formation of highly localized wall ingrowth structures in diverse cell types appears to be an ancient anatomical adaption to facilitate enhanced rates of apoplasmic transport of nutrients in plants. In some systems a role for transfer cells in the formation of an anti-pathogen protective barrier at these symplastic discontinuities has been inferred. Remarkably, the extent of cell wall ingrowth development at a particular site can show high plasticity, suggesting that transfer cell differentiation might be a dynamic process adapted to the transport requirements of each physiological condition. Recent studies exploiting different experimental systems to investigate transfer cell biology have identified signaling pathways inducing transfer cell development and genes/gene networks that define transfer cell identity and/or are involved in building the wall ingrowth labyrinths themselves. Further studies have defined the structure and composition of wall ingrowths in different systems, leading in many instances to the conclusion that this process may involve previously uncharacterized mechanisms for localized wall deposition in plants. Since transfer cells play important roles in plant development and productivity, the latter being relevant to crop yield, especially so in major agricultural species such as wheat, barley, soybean and maize, understanding the molecular and cellular events leading to wall ingrowth deposition holds exciting promise to develop new strategies to improve plant performance, a key imperative in addressing global food security. This Research Topic presents a timely and comprehensive treatise on transfer cell biology to help define critical questions for future research and thereby generating a deeper understanding of these fascinating and important cells in plant biology.
    Keywords: QK1-989 ; Q1-390 ; Wall ingrowth ; Arabidopsis thaliana ; synctial cells ; Zea mays ; transfer cells ; endosperm transfer cells ; Giant Cells ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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  • 89
    Publication Date: 2024-04-05
    Description: Research during the past decade highlights the strong link between appetitive feeding behavior, reward and motivation. Interestingly, stress levels can affect feeding behavior by manipulating hypothalamic circuits and brain dopaminergic reward pathways. Indeed, animals and people will increase or decrease their feeding responses when stressed. In many cases acute stress leads to a decrease in food intake, yet chronic social stressors are associated to increases in caloric intake and adiposity. Interestingly, mood disorders and the treatments used to manage these disorders are also associated with changes in appetite and body weight. These data suggest a strong interaction between the systems that regulate feeding and metabolism and those that regulate mood. This Research Topic aims to illustrate how hormonal mechanisms regulate the nexus between feeding behavior and stress. It focuses on the hormonal regulation of hypothalamic circuits and/or brain dopaminergic systems, as the potential sites controlling the converging pathways between feeding behavior and stress.
    Keywords: RC321-571 ; Q1-390 ; stress ; Obesity ; Dopamine ; Ghrelin ; Leptin ; Seasonal regulation ; feeding ; HPA axis ; Hypothalamus ; circadian rhythms ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 90
    Publication Date: 2024-04-05
    Description: euromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
    Keywords: RC321-571 ; Q1-390 ; Informed Consent ; Deep Brain Stimulation ; Depression ; Neurosurgery ; Movement Disorders ; Neuromodulation ; Enhancement ; Neuroethics ; Philosophy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 91
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Mit "Kolchosprosa" (kolchoznaja proza) und "Dorfprosa" (derevenskaja proza) greift die vorliegende Arbeit zwei im literarischen Leben der Sowjetunion entstandene Kategorien auf, die sich auf einander ablösende synchrone Schnitte im Evolutionsprozeß einer spezifischen literarischen Unterreihe beziehen. Die Grenze zwischen den beiden Schnitten entspricht ungefähr der Grenze zwischen den fünfziger und sechziger Jahren.
    Keywords: Dorfprosa ; einer ; Evolution ; fünfziger ; Jahre ; Kolchos ; literarischen ; Literaturwissenschaft ; Philologie ; Prosa ; Russland ; sechziger ; Slavische Sprachwissenschaft ; sowjetische ; Unterreihe ; Witte ; thema EDItEUR::D Biography, Literature and Literary studies
    Language: German
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  • 92
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Germany has gradually become Europe's largest immigration country and is increasingly shaped by the image of a multicultural and multilingual society. However, the issue of multilingualism receives little attention, especially with regard to Slavic migration idioms. The aim of the present study is the empirical investigation of the current language behavior of Slavophone immigrants and the determination of the vitality of their native languages. On the basis of a nationwide survey of 500 immigrants detailed microsociological data on the use of Slavic languages ​​depending on persons, topics and situations will be collected and the influence of linguistic ecological factors such as attitudes, motivations, identity and social network of speakers on language use and language content will be investigated. In addition, on the basis of interdisciplinary approaches to the description of linguistic minorities, the vitality of slavins is analyzed comparatively, showing the current situation and the future development of Slavia in Germany in general and specific tendencies of ethnolects in particular.
    Description: Deutschland hat sich sukzessive zum größten Einwanderungsland Europas entwickelt und wird immer stärker vom Bild einer multikulturellen und multilingualen Gesellschaft geprägt. Dem Thema Mehrsprachigkeit aber wird insbesondere in Bezug auf slavische Migrationsidiome nur wenig Beachtung geschenkt. Ziel der vorliegenden Studie ist die empirische Erforschung des aktuellen Sprachverhaltens slavophoner Immigranten und die Bestimmung der Vitalität ihrer Muttersprachen. Anhand einer deutschlandweiten Enquete unter 500 Zuwanderern werden detaillierte mikrosoziologische Daten zum Gebrauch der slavischen Sprachen in Abhängigkeit von Personen, Themen und Situationen erhoben und der Einfluss sprachökologischer Faktoren wie Attitüden, Motivationen, Identität und soziales Netzwerk der Sprecher auf die Sprachverwendung und den Spracherhalt untersucht. Zudem wird auf der Grundlage interdisziplinärer Ansätze zur Beschreibung von Sprachminderheiten die Vitalität der Slavinen komparativ analysiert, womit die gegenwärtige Situation und die zukünftige Entwicklung der Slavia in Deutschland im Allgemeinen und spezifische Tendenzen der Ethnolekte im Besonderen aufgezeigt werden.
    Keywords: Germany ; migration idioms ; immigration ; Achterberg ; Deutschland ; Ethnolinguistischen Vitalität ; Idiome ; Immigrantensprachen ; Immigration nach Deutschland ; Mehrsprachigkeit ; slavischer ; Sprachkontakt ; Vitalität ; thema EDItEUR::C Language and Linguistics::CF Linguistics
    Language: German
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  • 93
    Publication Date: 2024-03-29
    Description: The integration of multisensory information is an essential mechanism in perception and in controlling actions. Research in multisensory integration is concerned with how the information from the different sensory modalities, such as the senses of vision, hearing, smell, taste, touch, and proprioception, are integrated to a coherent representation of objects. Multisensory integration is central for action control. For instance, when you grasp for a rubber duck, you can see its size and hear the sound it produces. Moreover, identical physical properties of an object can be provided by different senses. You can both see and feel the size of the rubber duck. Even when you grasp for the rubber duck with a tool (e.g. with tongs), the information from the hand, from the effect points of the tool and from the eyes are integrated in a manner to act successfully. Over the recent decade a surge of interest in multisensory integration and action control has been witnessed, especially in connection with the idea that multiple sensory sources are integrated in an optimized way. For this perspective to mature, it will be helpful to delve deeper into the information processing mechanisms and their neural correlates, asking about the range and constraints of this mechanisms, about its localization and involved networks.
    Keywords: BF1-990 ; Q1-390 ; recalibration ; haptic ; Human Information Processing ; Vision ; Perception ; reference frame ; Acoustics ; Tool Use ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 94
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    Springer Nature | Springer
    Publication Date: 2024-04-01
    Description: This open access book describes the latest advances in the anal incontinence diagnostic and therapeutic processes. Anal incontinence is a devastating condition heavily impacting on the patients’ lives. Those suffering from this disorder are generally very embarrassed and reluctant to undergo an appropriate clinical evaluation, thus becoming more isolated and worsening the quality of their life. Luckily, nowadays a wide range of treatments is available to improve this oppressive condition; however, the recognition of the related pathophysiological alterations is mandatory to grant its successful management. This volume will help the surgeons community to keep abreast of developments in diagnostics and treatment of this impairing condition. and will provide all health professionals with the appropriate tools to face this impairing condition.
    Keywords: Continence mechanism ; Fecal incontinence ; Pelviperineal disorders ; Anal sphincter ; Continence Surgery ; thema EDItEUR::M Medicine and Nursing::MN Surgery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJH Gastroenterology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJS Urology and urogenital medicine ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKS Medical imaging::MKSH Medical imaging: radiology
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  • 95
    Publication Date: 2024-04-05
    Description: Volume I, entitled “Augmentation of Brain Functions: Brain-Machine Interfaces”, is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
    Keywords: RC321-571 ; Q1-390 ; microcircuits ; Brain machine interface (BMI) ; nootropics ; tDCStranscranial direct current stimulation ; neural networks ; neuroprosthesis ; TMS ; implants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 96
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-30
    Description: Controllerbereich und Interne Revision werden im Rahmen einer effizienten Unternehmenssteuerung und -überwachung in Forschung und Praxis getrennt voneinander zentrale Rollen beigemessen. Forschungsdefizite bestehen jedoch hinsichtlich ihres Kooperationspotenzials. Diese Arbeit liefert konkrete Hinweise, wie eine Kooperation dieser beiden Unternehmensbereiche erfolgreich ausgestaltet werden kann und somit zum Unternehmenserfolg beiträgt. Als Grundlage dieser Handlungsempfehlungen dienen die Erkenntnisse aus einer empirischen Untersuchung deutscher Unternehmen. Dieses Buch spricht Wissenschaftler, Praktiker und Studierende an, die sich einen Überblick über die Erfolgsfaktoren und Auswirkungen einer erfolgreichen Zusammenarbeit von Controllerbereich und Interner Revision verschaffen wollen.
    Keywords: Auswirkungen ; Binner ; Controllerbereich ; Controllerbereich ; deutscher ; Eine ; empirische ; Erfolgsfaktoren ; Interne Revision ; Interner ; Kooperation ; Revision ; Unternehmen ; Unternehmenssteuerung ; Untersuchung ; thema EDItEUR::K Economics, Finance, Business and Management::KF Finance and accounting::KFC Accounting::KFCX Accounting: study and revision guides
    Language: German
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  • 97
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-24
    Description: Slavic languages
    Keywords: Slavic languages ; thema EDItEUR::C Language and Linguistics::CJ Language teaching and learning
    Language: German
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  • 98
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    Peter Lang International Academic Publishing Group
    Publication Date: 2024-03-30
    Description: Ausgelöst durch zahlreiche Unternehmenskrisen wird seit Beginn der 90er Jahre in der Corporate Governance-Diskussion die Funktionsfähigkeit des deutschen Aufsichtsratssystems in Frage gestellt. Der Gesetzgeber reagierte hierauf zunächst mit dem KonTraG und zuletzt mit dem TransPuG. 〈BR〉 Der Autor entwickelt aus betriebswirtschaftlicher Perspektive Gestaltungsvorschläge, die zu einer Funktionsverbesserung des Aufsichtsrats beitragen. Ausgehend von einer Analyse der juristischen Rahmenbedingungen zeigt der Autor, daß ein wesentlicher Teil der Aufsichtsratsaufgaben zukunftsbezogen ist. Zur Erfüllung dieser Aufgaben sollten Aktiengesellschaften daher über ein Aufsichtsratsplanungssystem verfügen, das die Aufsichtsratsmitglieder umfassend unterstützt. Es wird ein theoretisch fundiertes Gesamtsystem entwickelt, das sich durch hohe praktische Umsetzbarkeit auszeichnet. Zur Förderung der notwendigen Professionalisierung des Aufsichtsrats wird außerdem ein wertorientiertes Anreizsystem gestaltet, das das Planungssystem ergänzen muß.
    Keywords: Aufsichtsratsplanungssysteme ; Ausgestaltung ; Betriebsrat ; Gremium ; Grundlagen ; praktische ; Publikumsaktiengesellschaften ; Ruhwedel ; Tarifplanung ; Theoretische ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJB Business studies: general ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJU Organizational theory and behaviour ; thema EDItEUR::L Law::LA Jurisprudence and general issues
    Language: German
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  • 99
    Publication Date: 2022-05-12
    Description: 〈P〉Die Südosteuropa-Studien werden von der in München ansässigen Südosteuropa-Gesellschaft, der wichtigsten Wissenschaftsorganisation der Südosteuropa-Forschung im deutschsprachigen Raum, herausgegeben. Sie dienen der vertieften und interdisziplinären wissenschaftlichen Darstellung wichtiger Themen aus der Südosteuropa-Forschung. Auch Fragen zur aktuellen politischen und sozio-ökonomischen Entwicklung in der Region Südosteuropa werden aufgegriffen. Herausgeber der Einzelbände sind renommierte Repräsentanten der deutschen und internationalen Südosteuropa-Forschung.〈/P〉
    Keywords: Bibliographie ; Bibliothek ; Donau ; einschlägigen ; Gamst ; Instituts ; Kiel ; Schrifttums ; Slavische Sprachwissenschaft ; Südosteuropa ; Universität ; Verzeichnis ; vorhandenen ; Weltwirtschaft ; Weltwirtschaft ; Wirtschaft ; bic Book Industry Communication::J Society & social sciences
    Language: German
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  • 100
    Publication Date: 2023-12-21
    Description: Gamma/delta (γδ) T-cells are a small subset of T-lymphocytes in the peripheral circulation but constitute a major T-cell population at other anatomical localizations such as the epithelial tissues. In contrast to conventional a/ß T-cells, the available number of germline genes coding for T-cell receptor (TCR) variable elements of γδ T-cells is very small. Moreover, there is a prefential localization of γδ T-cells expressing given Vgamma and Vdelta genes in certain tissues. In humans, γδ T-cells expressing the Vg9Vd2-encoded TCR account for anywhere between 50 and 〉95% of peripheral blood γδ T-cells, whereas cells expressing non-Vd2 genes dominate in mucosal tissues. In mice, there is an ordered appearance of γδ T-cell „waves“ during embryonic development, resulting in preferential localization of γδ T-cells expressing distinct VgammaVdelta genes in the skin, the reproductive organs, or gut epithelia. The major function of γδ T-cells resides in local immunosurveillance and immune defense against infection and malignancy. This is supported by the identification of ligands that are selectively recognized by the γδ TCR. As an example, human Vgamma9Vdelta2 T-cells recognize phosphorylated metabolites („phosphoantigens“) that are secreted by many pathogens but can also be overproduced by tumor cells, providing a basis for a role of these γδ T-cells in both anti-infective and anti-tumor immunity. Similarly, the recognition of endothelial protein C receptor by human non-Vdelta2 γδ T-cells has recently been identified to provide a link for the role for such γδ T-cells in immunity against epithelial tumor cells and cytomegalovirus-infected endothelial cells. In addition to „classical“ functions such as cytokine production and cytotoxicity, recent studies suggest that subsets of γδ T-cells can exert additional functions such as regulatory activity and – quite surpisingly – „professional“ antigen-presenting capacity. It is currently not well known how this tremendous extent of functional plasticity is regulated and what is the extent of γδ TCR ligand diversity. Due to their non-MHC-restricted recognition of unusual stress-associated ligands, γδ T-cells have raised great interest as to their potential translational application in cell-based immunotherapy. Topics of this Research Focus include: Molecular insights into the activation and differentiation requirements of γδ T-cells, role of pyrophosphates and butyrophilin molecules for the activation of human γδ T-cells, role of γδ T-cells in tumor immunity and in other infectious and non-infectious diseases, and many others. We are most grateful to all colleagues who agreed to write a manuscript. Thanks to their contributions, this E-book presents an up-to-date overview on many facets of the still exciting γδ T-cells.
    Keywords: R5-920 ; RC581-607 ; Infection ; Butyrophilin 3A1 ; Tumor-infiltrating lymphocytes ; cancer immunotherapy ; IL-17 ; Pyrophosphates ; bic Book Industry Communication::M Medicine
    Language: English
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