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  • Q1-390  (1,621)
  • thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology  (1,259)
  • thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general  (856)
  • English  (3,598)
  • French  (133)
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  • 1
    Publication Date: 2024-04-05
    Description: After a quarter of century of rapid technological advances, research has revealed the complexity of cancer, a disease intimately related to the dynamic transformation of the genome. However, the full understanding of the molecular onset of this disease is still far from achieved and the search for mechanisms of treatment will follow closely. It is here that Nanotechnology enters the fray offering a wealth of tools to diagnose and treat cancer. In fact, the National Cancer Institute predicts that over the next years, nanotechnology will result in important advances in early detection, molecular imaging, targeted and multifunctional therapeutics, prevention and control of cancer. Nanotechnology offers numerous tools to diagnose and treat cancer, such as new imaging agents, multifunctional devices capable of overcome biological barriers to deliver therapeutic agents directly to cells and tissues involved in cancer growth and metastasis, and devices capable of predicting molecular changes to prevent action against precancerous cells. Nanomaterials-based delivery systems in Theranostics (Diagnostics & Therapy) provide better penetration of therapeutic and diagnostic substances within the body at a reduced risk in comparison to conventional therapies. At the present time, there is a growing need to enhance the capability of theranostics procedures where nanomaterials-based sensors may provide for the simultaneous detection of several gene-associated conditions and nanodevices with the ability to monitor real-time drug action. These innovative multifunctional nanocarriers for cancer theranostics may allow the development of diagnostics systems such as colorimetric and immunoassays, and in therapy approaches through gene therapy, drug delivery and tumor targeting systems in cancer. Some of the thousands and thousands of published nanosystems so far will most likely revolutionize our understanding of biological mechanisms and push forward the clinical practice through their integration in future diagnostics platforms. Nevertheless, despite the significant efforts towards the use of nanomaterials in biologically relevant research, more in vivo studies are needed to assess the applicability of these materials as delivery agents. In fact, only a few went through feasible clinical trials. Nanomaterials have to serve as the norm rather than an exception in the future conventional cancer treatments. Future in vivo work will need to carefully consider the correct choice of chemical modifications to incorporate into the multifunctional nanocarriers to avoid activation off-target, side effects and toxicity. Moreover the majority of studies on nanomaterials do not consider the final application to guide the design of nanomaterial. Instead, the focus is predominantly on engineering materials with specific physical or chemical properties. It is imperative to learn how advances in nanosystem’s capabilities are being used to identify new diagnostic and therapy tools driving the development of personalized medicine in oncology; discover how integrating cancer research and nanotechnology modeling can help patient diagnosis and treatment; recognize how to translate nanotheranostics data into an actionable clinical strategy; discuss with industry leaders how nanotheranostics is evolving and what the impact is on current research efforts; and last but not least, learn what approaches are proving fruitful in turning promising clinical data into treatment realities.
    Keywords: QD1-999 ; Q1-390 ; Nanoparticles ; Gene Therapy ; Immunotherapy ; bioimaging ; theranostics ; nanomaterials ; Drug delivery ; Nanomedicine ; Cancer ; Phototherapy ; thema EDItEUR::P Mathematics and Science::PN Chemistry
    Language: English
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  • 2
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    Collège de France
    Publication Date: 2022-02-01
    Description: La théorie de Darwin aussi bien que sa réception scientifique, littéraire et politique en France continuent d’être matière à débat. Les controverses qu’elle a suscitées à partir de la première traduction française de L’Origine des espèces en 1862 n’ont pas été le seul fait des naturalistes, des géologues ou des paléontologues. De nombreux autres savants se sont préoccupés de l’impact du darwinisme sur leur discipline, notamment en philologie, dans les mathématiques, la linguistique, la psychologie comparée, l’histoire ou la philosophie. Les auteurs des textes réunis dans Darwin au Collège de France montrent que le Collège de France constitue un point de référence idéal pour étudier les idées de Darwin et leur réception ainsi que la manière dont elles ont pu jouer sur la formation des disciplines du milieu du xixe siècle jusqu’à aujourd’hui. Parmi les défenseurs ou les adversaires français du darwinisme, on compte en effet plusieurs de ses professeurs, à commencer par Pierre Flourens, dont l’Examen du livre de M. Darwin (1864) a été l’un des premiers comptes rendus hostiles de L’Origine des espèces. D’autres figurent encore dans la liste : Ernest Renan, Edgar Quinet, Théodule Ribot, Jean-Charles Lévêque, Étienne-Jules Marey, Jean-François Nourrisson, Michel Bréal, Gabriel Tarde, Henri Bergson, Étienne Gilson. À cette liste s’ajoutent les professeurs de biologie, de médecine, de paléontologie, de neurosciences, ou d’économie politique. Le colloque, dont les contributions sur quelques-uns des savants mentionnés ci-dessus sont réunies dans le deuxième volume de la collection « Passage des disciplines », a été organisé par Alain Prochiantz et Antoine Compagnon dans le cadre du projet « Passage des disciplines : Histoire globale du Collège de France, xixe siècle - xxe siècle », qui s’intéresse à l’évolution des matières enseignées aussi bien que celles qui ont n’y ont pas été admises et qui forment un « Collège virtuel », depuis la fin du xviiie siècle jusqu’aux années 1960. Il est dirigé par Antoine Compagnon, avec la collaboration de Céline Surprenant et le soutien financier de PSL (2016-2019), et de la Fondation Hugot.
    Keywords: P ; D1-2009 ; PN1-6790 ; B1-5802 ; H1-99 ; Q1-390 ; literary criticism ; biology ; psychology ; history of sciences ; social sciences ; literary history ; higher education ; life sciences ; history of ideas ; philosophy ; research
    Language: French
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: Anthropogenic greenhouse gas (GHG) emissions are dramatically influencing the environment, and research is strongly committed to proposing alternatives, mainly based on renewable energy sources. Low GHG electricity production from renewables is well established but issues of grid balancing are limiting their application. Energy storage is a key topic for the further deployment of renewable energy production. Besides batteries and other types of electrical storage, electrofuels and bioderived fuels may offer suitable alternatives in some specific scenarios. This Special Issue includes contributions on the energy conversion technologies and use, energy storage, technologies integration, e-fuels, and pilot and large-scale applications.
    Keywords: Q1-390 ; QC1-999 ; n/a ; PV ; GHG savings ; lithium-ion battery (LIB) ; probability prediction ; decarbonization ; supercapacitor (SC) ; least squares support vector machine ; EV fleet forecasts ; alternative maritime power (AMP) ; Markov chain ; feasibility study ; D funding ; hybrid power system ; numerical analysis ; ship structure ; optimal sizing ; cellulosic ethanol ; electric vehicles EV ; biofuel ; green ship ; R&amp ; bulk carrier ; molten carbonate fuel cell system ; sparse Gaussian process regression ; power-to-gas ; combination method ; charging infrastructure ; jet fuel ; flow characteristics ; hybrid refinery ; LNG-fueled ship ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: English
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  • 4
    Publication Date: 2024-04-11
    Description: It has become more evident that many microalgae respond very differently than land plants to diverse stimuli. Therefore, we cannot reduce microalgae biology to what we have learned from land plants biology. However, we are still at the beginning of a comprehensive understanding of microalgae biology. Microalgae have been posited several times as prime candidates for the development of sustainable energy platforms, making thus the in-depth understanding of their biological features an important objective. Thus, the knowledge related to the basics of microalgae biology must be acquired and shared rapidly, fostering the development of potential applications. Microalgae biology has been studied for more than forty years now and more intensely since the 1970’s, when genetics and molecular biology approaches were integrated into the research programs. Recently, studies on the molecular physiology of microalgae have provided evidences on the particularities of these organisms, mainly in model species, such as Chlamydomonas reinhardtii. Of note, cellular responses in microalgae produce very interesting phenotypes, such as high lipid content in nitrogen deprived cells, increased protein content in cells under high CO2 concentrations, the modification of flagella structure and motility in basal body mutant strains, the different ancient proteins that microalgae uses to dissipate the harmful excess of light energy, the hydrogen production in cells under sulfur deprivation, to mention just a few. Moreover, several research groups are using high-throughput and data-driven technologies, including “omics” approaches to investigate microalgae cellular responses at a system-wide level, revealing new features of microalgae biology, highlighting differences between microalgae and land plants. It has been amazing to observe the efforts towards the development and optimization of new technologies required for the proper study of microalgae, including methods that opened new paths to the investigation of important processes such as regulatory mechanisms, signaling crosstalk, chemotactic mechanisms, light responses, chloroplast controlled mechanisms, among others. This is an exciting moment in microalgae research when novel data are been produced and applied by research groups from different areas, such as bioprocesses and biotechnology. Moreover, there has been an increased amount of research groups focused in the study of microalgae as a sustainable source for bioremediation, synthesis of bioproducts and development of bioenergy. Innovative strategies are combining the knowledge of basic sciences on microalgae into their applied processes, resulting in the progression of many applications that hopefully, will achieve the necessary degree of optimization for economically feasible large-scale applications. Advances on the areas of basic microalgae biology and novelties on the essential cellular processes were revealed. Progress in the applied science showed the use of the basic science knowledge into fostering translational research, proposing novel strategies for a sustainable world scenario. In this present e-book, articles presented by research groups from different scientific areas showed, successfully, the increased development of the microalgae research. Herewith, you will find articles ranging from bioprospecting regional microalgae species, through advances in microalgae molecular physiology to the development of techniques for characterization of biomass and the use of biomass into agriculture and bioenergy production. This e-book is an excellent source of knowledge for those working with microalgae basic and applied sciences, and a great opportunity for researchers from both areas to have an overview of the amazing possibilities we have for building an environmentally sustainable future once the knowledge is translated into novel applications.
    Keywords: TA1-2040 ; TP248.13-248.65 ; QK1-989 ; Q1-390 ; Biotechnology ; biomass ; Hydrogen ; bioenergy ; Nutrients ; Lipids ; Microalgae ; Biofuels ; sustainability ; Carbon Dioxide ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In recent years, the fascination with shape memory alloys (SMAs) has grown across industries such as aerospace, automotive, naval, civil, and biology. SMAs possess unique properties, including the ability to recover from deformation when heated, exhibit pseudoelastic stress-strain behavior for large deformations, and exceptional biocompatibility for bioengineering applications. However, a comprehensive understanding of critical characteristics like transformation temperature and stress values is necessary to fully utilize SMAs. The shape memory effect, where SMAs regain their original shape after deformation under specific thermal conditions, has driven innovative applications in various sectors. In aerospace, SMAs are used in wing structures and actuation systems, enabling morphing and improving aerodynamics. In healthcare, they are integrated into orthopedic devices, simplifying surgical procedures and providing necessary support. The automotive industry also benefits from SMAs, using them in seatbelts and vibration damping systems for enhanced safety and comfort. Accurate knowledge of critical characteristics is essential for effective utilization of SMAs, unlocking their potential in different fields. The remarkable versatility of SMAs, with their deformation recovery, pseudoelasticity, and biocompatibility, positions them as a material of immense interest. As research and development continue, SMAs are poised to drive future innovations, shaping various industries.
    Keywords: shape memory alloy (SMAs) ; shape memory effect (SME) ; superelasticity ; smart materials ; constitutive models ; simulation and modeling ; smart devices ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Mg alloy is the lightest metallic structural material and possesses the advantages of high specific strength, high specific stiffness, good electromagnetism shield, good damping capacity, good machinability, and easy recycling, etc. Therefore, it has extremely broad application prospects and has drawn considerable interest in the fields of automobile, electronics, electrical appliances, transportation, aerospace, and aviation. In addition, Mg alloys are gradually showing application potential in emerging industries, serving as biodegradable metals in the biomedical field, functional material for hydrogen storage, and so on. This Special Issue (SI), entitled “Research Progress in High-Performance Magnesium Alloy and Its Applications”, presents recent developments and excellent results in the field of Mg alloys, and includes 10 articles and one editorial covering some interesting aspects of the topic.
    Keywords: grain refinement ; high strength and toughness ; {10–12} twin ; Mg-Gd-Y alloy ; multidirectional impact forging ; Mg-Zn-Mn-Ca ; Ca2Mg6Zn3 phase ; corrosion behaviors ; SKPFM ; boride ; MgB2 ; mechanical alloying ; ignition ; combustion ; flame temperature ; magnesium alloy ; biocompatibility ; surface coating modification ; corrosion resistance ; implantable bio-metal materials ; filler material ; welding ; scandium ; microstructure modification ; mechanical properties ; microstructure ; texture ; stretch formability ; high temperature cross-rolling ; annealing ; wire arc additive manufacturing ; cold metal transfer ; Al-Mg alloys ; orthogonal experiment ; Mg-Bi-Ca alloy ; hot deformation ; constitutive model ; dynamic recrystallization kinetics ; Mg alloy ; twinning ; random orientation ; compression ; room temperature ; backward extrusion ; tensile strength ; failure mechanism ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 7
    Publication Date: 2024-04-05
    Description: In the past two decades there have been significant advances made in understanding the cellular and molecular alterations that occur with brain ageing, as well as with our understanding of age-related brain diseases. Ageing is associated with a mid-life decline in many cognitive domains (eg. Attention, working memory, episodic memory) that progresses with advancing age and which may be potentiated by a variety of diseases. However, despite the breadth of attempts to explain it, the underlying basis for age-related memory impairment remains poorly understood. Both normal and “pathological” ageing (as in age-related neurodegenerative disorders such as Alzheimer’s disease) may be associated with overlapping and increased levels of “abnormal” pathology, and this may be a potential mediator of cognitive decline in both populations. An emerging hypothesis in this field is that metal ion dys/homeostasis may represent a primary unifying mechanism to explain age- and disease-associated memory impairment – either indirectly via an effect on disease pathogenesis, or by a direct effect on signaling pathways relevant to learning and memory. There remains a concerted worldwide effort to deliver an effective therapeutic treatment for cognitive decline associated with ageing and/or disease, which is currently an unmet need. There have been numerous clinical trials conducted specifically testing drugs to prevent cognitive decline and progression to dementia, but to date the results have been less than impressive, highlighting the urgent need for a greater understanding of the neurobiological basis of memory impairment in ageing and disease which can then drive the search for effective therapeutics.
    Keywords: RC321-571 ; Q1-390 ; Down Syndrome ; Amyotrophic Lateral Sclerosis ; Parkinson's disease ; aluminium ; Iron ; TBI ; Cognition ; Copper ; Alzheimer's disease ; Zinc ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Metalliferous minerals play a central role in the global economy. They will continue to provide the raw materials we need for industrial processes. Significant challenges will likely emerge if the climate-driven green and low-carbon development transition of metalliferous mineral exploitation is not managed responsibly and sustainably. Green low-carbon technology is vital to promote the development of metalliferous mineral resources shifting from extensive and destructive mining to clean and energy-saving mining in future decades. Global mining scientists and engineers have conducted a lot of research in related fields, such as green mining, ecological mining, energy-saving mining, and mining solid waste recycling, and have achieved a great deal of innovative progress and achievements. This Special Issue intends to collect the latest developments in the green low-carbon mining field, written by well-known researchers who have contributed to the innovation of new technologies, process optimization methods, or energy-saving techniques in metalliferous minerals development.
    Keywords: metallurgical slag-based binders ; solidification/stabilisation ; As(III) ; As(V) ; calcium hydroxide ; sublevel caving ; numerical simulation ; physical model ; structural parameter ; green mining ; limestone ; high temperature ; confining pressure ; SHPB ; constitutive model ; open-pit mine ; PLAXIS 3D ; dynamic load ; safety factor ; acceleration ; particle sedimentation ; filling mining ; degree of influence ; pipeline transportation ; solid waste utilization ; tailings ; reclamation risk ; hazard identification ; complex network ; hazard management ; digital mine ; mine short-term production planning ; haulage equipment dispatch plan ; ABCA ; NSGA ; settlement velocity measurement ; K-means ; tailings backfill ; unsupervised learning ; cemented paste backfill ; ESEM ; picture processing ; floc networks ; pumping agent ; fractal dimension ; backfill slurry ; strength of cemented backfill ; inhomogeneity of cemented backfill ; cemented tailings backfill ; copper ; zinc ; recovery ; sulfide concentrate ; artificial microbial community ; granular backfill ; bearing characteristics ; numerical model ; particle size ; surface subsidence ; blasting dust movement ; dust concentration ; particle size distribution ; blasting dust reduction ; backfill ; metal mine ; log-sigmoid ; tailings pond ; regional distribution ; dam break ; accident statistics ; causation analysis ; backfilling ; increasing resistance and reducing pressure ; computational fluid dynamics ; spiral pipe ; stowing gradient ; coal-based solid waste ; orthogonal experiment ; strength development ; regression analysis ; engineering performance ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTU Mining technology and engineering
    Language: English
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  • 9
    Publication Date: 2024-04-05
    Description: Neuromorphic engineering has just reached its 25th year as a discipline. In the first two decades neuromorphic engineers focused on building models of sensors, such as silicon cochleas and retinas, and building blocks such as silicon neurons and synapses. These designs have honed our skills in implementing sensors and neural networks in VLSI using analog and mixed mode circuits. Over the last decade the address event representation has been used to interface devices and computers from different designers and even different groups. This facility has been essential for our ability to combine sensors, neural networks, and actuators into neuromorphic systems. More recently, several big projects have emerged to build very large scale neuromorphic systems. The Telluride Neuromorphic Engineering Workshop (since 1994) and the CapoCaccia Cognitive Neuromorphic Engineering Workshop (since 2009) have been instrumental not only in creating a strongly connected research community, but also in introducing different groups to each other’s hardware. Many neuromorphic systems are first created at one of these workshops. With this special research topic, we showcase the state-of-the-art in neuromorphic systems.
    Keywords: RC321-571 ; Q1-390 ; neuromorphic engineering ; Learning ; Floating gate ; Neural Network ; spike-based ; event-based ; simulation ; dynamic vision sensor ; network ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 10
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Despite the importance of mathematics in our educational systems little is known about how abstract mathematical thinking emerges. Under the uniting thread of mathematical development, we hope to connect researchers from various backgrounds to provide an integrated view of abstract mathematical cognition. Much progress has been made in the last 20 years on how numeracy is acquired. Experimental psychology has brought to light the fact that numerical cognition stems from spatial cognition. The findings from neuroimaging and single cell recording experiments converge to show that numerical representations take place in the intraparietal sulcus. Further research has demonstrated that supplementary neural networks might be recruited to carry out subtasks; for example, the retrieval of arithmetic facts is done by the angular gyrus. Now that the neural networks in charge of basic mathematical cognition are identified, we can move onto the stage where we seek to understand how these basics skills are used to support the acquisition and use of abstract mathematical concepts.
    Keywords: RC321-571 ; Q1-390 ; Neuroimaging ; development ; numerosity ; gifted ; Mathematical Cognition ; algebra ; abstract ; Expertise ; Arithmetic ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Elastomer materials are characterized by their high elongation and (entropy) elasticity, which makes them indispensable for widespread applications in various engineering and medical areas as well as consumer goods. This book focuses on the state-of-the-art of elastomers covering all aspects from their properties to applications. The development and testing of advanced elastomers is of particular interest. Attention is given to various aspects of elastomers, such as ever-increasing environmental concepts dealing with recyclability and reusability, incorporation of functional groups or additives to obtain novel functionality or bioelastomers, analytical description of mechanisms and structure relations of the fracture behavior of elastomers, and their external stimuli-responsive character. The scope of the book encompasses contributions at the frontier of science in polymer network synthesis, experimental and theoretical physics of polymer networks, and new structures and functionalities incorporated into elastomers leading to enhanced properties of crosslinked elastomeric materials, among others.
    Keywords: magnetorheological elastomer ; filler ; hetero-aggregation ; nanosized Ni-Mg cobalt ferrites ; electrical resistance ; resistivity ; rheological properties ; elastomers ; in-situ silica ; friction ; abrasion ; tear fatigue test ; buffing dust collagen (BDC) ; styrene–butadiene rubber (SBR) ; polymer composites ; biodegradation ; bio-oil ; bio-based plasticizer ; eco-friendly plasticizer ; acrylonitrile-butadiene rubber ; NBR ; mechanical testing ; thermo-oxidative aging ; vulcanized rubber ; rubber compounds ; carbon black ; vibration damping ; viscoelasticity ; magnetorheological ; elastomer ; magnetic particle ; viscoelastic ; rheological ; smart materials ; coating ; particle coating ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In this Special Issue, we have several papers related to fuel-cell-based cogeneration systems; the management and control of fuel cell systems; the analysis, simulation, and operation of different types of fuel cells; modelling and online experimental validation; and the environment assessment of cathode materials in lithium-ion battery energy generation systems. A paper which gives a comprehensive review with technical guidelines for the design and operation of fuel cells, especially in a cogeneration system setup, which can be an important source of references for the optimal design and operation of various types of fuel cells in cogeneration systems, can also be found in this Special Issue.
    Keywords: LIBs ; environmental sustainability ; cathode material ; LCA ; wind energy ; fuel cell ; IM ; induction generator ; hybrid system ; mine blast optimizer ; solid oxide fuel cell ; robust model predictive control ; off-line calculation ; control synthesis ; review ; cogeneration ; optimal design ; guidelines ; SOFC ; simulation ; internal reforming ; anode oxidation ; carbon formation ; direct methanol fuel cell ; methanol crossover ; power density ; catalyst ; membrane electrode assembly ; Colebrook equation ; fuel cells ; flow friction factor ; open-cathode ; pressure drop ; symbolic regression ; numerically stabile solution ; roughness ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 13
    Publication Date: 2024-03-29
    Description: In the year 2013, ‘selfie’ was named word of the year by Oxford Dictionaries in recognition of dramatic changes in frequency, prominence, and register of the term. This drastic increase in selfie-taking was spurred by two factors. The first was the advent of smartphones equipped with front cameras and preview screens that made it easy to compose a photographic self-portrait by a process of deliberately exploring one’s image, choosing a pose, and finally taking the picture. The second key change contributing to the rise of the selfie age was the increasing availability of internet connections. It is estimated that about 50% of the world population has access to the internet today (2018; https://www.internetworldstats.com). At the end of the past century, this percentage was a mere 1%. The growth of the internet infrastructure simultaneously spurred the development of social network applications such as Facebook, Twitter, Snapchat, and Instagram, providing accessible media for sharing photographs including photographic self-portraits. However, despite their tremendous reach and popularity, selfies have so far received relatively little attention by the scientific community, especially within psychology. Thus, we proposed a Frontiers in Psychology Research Topic to expand empirical and theoretical work on the massively popular, yet scientifically unexplored, phenomenon of the selfie. The articles published in this eBook offer a multifaceted insight into current scholarly work on this topic.
    Keywords: BF1-990 ; Q1-390 ; group selfies ; self-esteem ; Human Computer Interaction (HCI) ; self-presentation ; selfie ; viewing perspective ; perception bias ; smartphones ; social media ; internet ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Smart materials and structures are capable of active or passive changes in terms of shapes, properties, and mechanical or electromagnetic responses in reaction to an external stimulus, such as light, temperature, stress, moisture, pH, and electric or magnetic fields. They have attracted increasing interest for their enhanced performance and efficiency over a wide range of industrial applications, especially for aerospace. These require novel engineering approaches and design philosophies in order to integrate the actions of sensors, actuators, and control circuit elements into a single system that can respond adaptively to its surroundings. This reprint has collected cutting-edge research and recent advances in smart materials and structures, including seven original research papers and three review articles, co-authored by 65 scientists and engineers from 18 institutions and 3 industries. The research topics mainly cover advanced materials, applications of smart materials and structures, as well as recent development in sensing techniques. We hope this reprint will contribute to disseminating the latest progress in smart materials and structures, as well as stimulate the interest of its audience to work in this important and vibrant area to promote and benefit the multidisciplinary scientific communities.
    Keywords: textile-based mechanical sensors ; mechanism ; preparation ; advantages ; applications ; Artificial Neural Network (ANN) ; guided waves ; Structural Health Monitoring (SHM) ; Finite Element Analysis (FEA) ; damage detection ; metals ; composites ; aeroelastic stability ; bladed disk ; intentional mistuning ; piezoelectric material ; topological optimization ; microstructure ; high-entropy alloy ; mechanical property ; bipedal robot ; dynamics simulation ; MRE isolator ; vibration reduction control algorithms ; no-core fiber ; polyaniline ; polyacrylic acid ; pH sensor ; multimode interference ; gas foil bearing ; Inconel alloy ; sensing foil ; strain field ; temperature field ; thermomechanical coupling ; thermomechanical characterization ; rotor dynamics ; turbomachinery ; cholesteric liquid crystals ; electro-optic response ; polymer stabilization ; ion-trapping mechanism ; liquid metal ; stretchable conductor ; 3D printing ; high dynamic stability ; wearable devices ; biomimetic ; Venus flytrap ; smart ; composite ; mechanics ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Non-Newtonian (non-linear) fluids are common in nature, for example, in mud and honey, but also in many chemical, biological, food, pharmaceutical, and personal care processing industries. This Special Issue of Fluids is dedicated to the recent advances in the mathematical and physical modeling of non-linear fluids with industrial applications, especially those concerned with CFD studies. These fluids include traditional non-Newtonian fluid models, electro- or magneto-rheological fluids, granular materials, slurries, drilling fluids, polymers, blood and other biofluids, mixtures of fluids and particles, etc.
    Keywords: TA1-2040 ; T1-995 ; Poiseuille–Couette flow ; membrane ; viscous fluid ; channel flow ; existence theorem ; yield stress ; hemoglobe capacitor ; creeping flows ; viscoplastic fluids ; projection method ; power-law fluid ; first- and second-order slip ; Mittag–Leffler ; lubrication ; viscoplastic fluid ; rupture ; convection ; Re numbers ; enhanced oil recovery (EOR) ; SPH-FEM ; Gamma densitometer ; oil recovery ; non-newtonian fluids ; marginal function ; particle interaction ; computational fluid dynamics ; non-isothermal flows ; suspensions ; Brinkman equation ; lubrication approximation (76A05 ; lid-driven cavity ; smoothed particle hydrodynamics (SPH) ; 76D08 ; Phan-Thien–Tanner (PTT) model ; bubble suspension ; porous media ; non-equilibrium thermodynamics ; porous medium ; suspension viscosity ; hemoglobin ; convection-diffusion ; slug translational velocity ; closure relationship ; non-linear fluids ; wormlike micellar solutions (WMS) ; high viscosity oil ; viscoelastic surfactants (VES) ; 76A20) ; meshless ; Bingham fluid ; Reynolds equation ; generalised simplified PTT ; dense suspension ; chemical EOR (cEOR) ; buoyancy force ; viscosity ratio ; aspect ratio ; rheology ; lubrication approximation ; fluid-solid interaction (FSI) ; optimal control ; natural convection ; biofluids ; shear-dependent viscosity ; thermodynamic capacitor ; shear-thinning ; stokesian dynamics ; weak solution ; biological capacitor ; cement ; variable viscosity ; Couette flow ; pressure boundary conditions ; inhomogeneous fluids ; boundary control ; similarity transformation ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The development of solid state gas sensors based on microtransducers and nanostructured sensing materials is the key point in the design of portable measurement systems able to reach sensing and identification performance comparable with analytical ones. In such a context several efforts must be spent of course in the development of the sensing material, but also in the choice of the transducer mechanism and its structure, in the electrical characterization of the performance and in the design of suitable measurement setups. This call for papers invites researchers worldwide to report about their novel results on the most recent advances and overview in design and measurements for applications in gas sensors, along with their relevant features and technological aspects. Original research papers are welcome (but not limited) on all aspects that focus on the most recent advances in: (i) basic principles and modeling of gas and VOCs sensors; (ii) new gas sensor principles and technologies; (iii) Characterization and measurements methodologies; (iv) transduction and sampling systems; (vi) package optimization; (vi) gas sensor based systems and applications.
    Keywords: TA1-2040 ; T1-995 ; indium oxide ; n/a ; environmental monitoring ; semiconductor ; gas sensor ; packed gas chromatographic column ; ultrathin carbon layer ; metal-oxide-semiconductor array sensor ; halitosis ; laser ablation ; capacitive micromachined ultrasonic transducers (CMUT) ; LTCC side via ; MEMS ; indirect packaging ; gas sensing ; efficiency ; bad breath ; electrospray ; array optimization ; low temperature co-fired ceramic (LTCC) ; electronic nose ; UV irradiation ; core/shell nanostructure ; combinatorial and high-throughput technique ; sensitive material ; hydrogen sulfide ; CO detection ; ZnO ; amperometric ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 17
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The use of concentrated solar technologies has grown significantly worldwide in the last decade but the research and development of this renewable energy technology still needs to be advanced to guarantee its competitiveness with other energy sources. Challenges remain with reducing costs, optimizing the systems design, and increasing the performance and durability of the systems.This Special Issue on research on solar collectors presents some recent developments and studies on tracking-solar collectors for medium- to high-temperature applications, both line- and point-focus systems, conceived for the supply of heat in industrial processes, to provide thermal energy to a power block for electricity production, or even to combine heat and electricity generation in a solar collector unit (CPV/T). The articles included in this Special Issue cover theoretical or practical issues on geometrics optics, thermal–hydraulic modelling, and performance analysis, focusing on the following topics:• Solar towers: heliostat fields analysis and optimization• Solar towers: heat transfer media studies• Parabolic troughs: evacuated solar receivers analysis and thermal–hydraulic modelling• Fresnel reflectors: geometrics optics and manufacturing issues• Fresnel lens in CPV• Energy losses in solar collectors systems
    Keywords: thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Concerns relating to energy supply and climate change have driven renewable energy targets around the world. Marine renewable energy could make a significant contribution to reducing greenhouse gas emissions and mitigating the consequences of climate change, while providing a high-technology industry. The conversion of wave and tidal energy into electricity has many advantages. Individual tidal and wave energy devices have been installed and proven, with commercial arrays planned throughout the world. The wave and tidal energy industry has developed rapidly in the past few years; therefore, it seems timely to review current research and map future challenges. Methods to improve understanding of the resource and interactions (between energy extraction, the resource and the environment) are considered, such as resource characterisation (including electricity output), design considerations (e.g., extreme and fatigue loadings) and environmental impacts, at all timescales (ranging from turbulence to decadal) and all spatial scales (from device and array scales to shelf sea scales).
    Keywords: tide-surge-wave model ; Taiwanese waters ; sea-state hindcast ; wave power ; wave energy ; unstructured grid model ; resource characterization ; WaveWatch III ; SWAN ; tidal energy ; experimental testing ; acoustic Doppler profiler ; Strangford Lough ; dc-dc bidirectional converter ; finite control set-model predictive control (FCS-MPC) ; oscillating water column (OWC) ; supercapacitor energy storage (SCES) ; wave climate variability ; wavelet analysis ; teleconnection patterns ; marine renewable energy ; ocean energy ; environmental effects ; wave modeling ; wave propagation ; numerical modeling ; sediment dynamics ; risk assessment ; marine current energy ; spiral involute blade ; hydrodynamic analysis ; numerical simulation ; wave energy trends ; reanalysis wave data ; Chilean coast ; renewable energy ; wave energy converters ; annual mean power production ; wave energy converter ; transmission coefficient ; absorption ; surfing amenity ; resource ; impact assessment ; feasibility study ; floating offshore wave farm ; WEC ; IRR ; LCOE ; marine energy ; unmanned ocean device ; multi-type floating bodies ; nonlinear Froude-Krylov force ; energy efficiency ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Processing and storage can cause changes and interactions in food components that have effects on nutritional value, organoleptic characteristics or even food safety. This book includes 19 research works showing important and interesting advances, as well as new approaches, in this research topic. Four articles are dedicated to studying the effect of canning conditions (filling media and some ingredients) on the diverse parameters of quality for fish and pet foods. Three articles are devoted to studying the effects of dehydration (pre-treatments and drying procedures). One article is dedicated to monitoring the elaboration of a fermented and dehydrated product (sausage) using a portable NIRS device. The ninth article of this book studies the effect of low-dose electron beam irradiation on cooking quality, moisture migration, and thermodynamics, as well as the digestion properties of the isolated starches in newly harvested and dried rice. The next contribution studies the use of different preservatives to avoid the formation of undesirable volatile organic compounds in stracciatella cheese. Another article examines the impact of source material, kibble size, temperature, and duration on the efficiency of the aqueous extraction of sugars and phenolics from carob kibbles by conventional heat-assisted (HAE) and ultrasound-assisted (UAE) methods. In two articles, marinating with different extracts, alone or combined with other seasoning/conditioning methods, was essayed to tenderize beef or to improve the sensory quality of chicken leg and breast meat. The effect of various cooking methods on the quality, structure, pasting, water distribution and protein oxidation of fish and meat-based snacks is studied in the fourteenth article. The last five articles are dedicated to the study of the effects of storage on several foods (olive oil, blueberry, beetroot and Atlantic mackerel).
    Keywords: Electron Beam Irradiation ; rice ; moisture ; physicochemical properties ; rabbiteye blueberry ; postharvest storage ; firmness ; aroma compounds ; off-odor ; dry-fermented sausages ; near infrared spectroscopy ; portable device ; PLS-DA ; Scomber colias ; prior chilling ; Fucus spiralis ; packaging medium ; canning ; lipid damage ; colour ; trimethylamine ; quality ; carob kibbles ; carob juice ; aqueous extraction ; sugars ; phenolics ; free amino acids ; biogenic amines ; filling medium ; European eels ; stracciatella cheese ; volatile organic compounds ; sensory characteristics ; natural preservatives ; cheese storage ; pineapple by-products ; hydrostatic pressure ; bromelain ; enzyme activity ; marinade ; meat ; texture ; water status and distribution ; microstructure ; secondary structure of protein ; Atlantic mackerel ; saffron quality ; secondary metabolites ; drying ; high performance liquid chromatography-diode array detection (HPLC-DAD) ; spectrophotometry ; canned eels ; olive oil ; sunflower oil ; oxidation ; antioxidants ; total phenols ; vitamin E ; fresh wet noodles ; humidity-controlled dehydration ; microorganisms ; shelf-life ; noodle quality ; “Rocha” pear ; ultrasound ; microwave ; quality characteristics ; empirical models ; beetroot ; organic farming ; storage ; bioactive compounds ; betalain ; nitrate ; sugar ; phenolic compounds ; total dry matter ; chicken meat ; sensory evaluation ; superheated steam ; marination ; hot smoking ; storage effect ; extra virgin olive oil ; phenols ; sterols ; tocopherols ; temperature ; argon ; freeze-thaw cycles ; anthocyanins ; gas chromatography-mass spectrometry ; aroma profiles ; hot-air drying ; blueberry ; cooking methods ; fish meat snacks ; LF-NMR ; SEM ; protein oxidation ; expressible moisture ; gel ; gum ; heat penetration ; thermally processed ; wet pet food ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
    Language: English
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  • 20
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: DNA methylation, a modification found in most species, regulates chromatin functions in conjunction with other epigenome modifications, such as histone post-translational modifications and non-coding RNAs. In mammals, DNA methylation has an essential role in development by orchestrating the generation and maintenance of the phenotypic diversity of human cell types. Recent years have brought spectacular advances in our understanding of the mechanism, function and regulation of DNA methyltransferases through their interaction with other epigenome modifications, chromatin factors and post-translational modifications, which are described in this Special Issue of Genes. Manuscripts are specifically addressing describing the targeting and regulation of DNA methyltransferases by interacting factors and their roles in cellular differentiation and the development of diseases. Prof. Dr. Albert Jeltsch and Prof. Dr. Humaira Gowher, Guest Editors
    Keywords: QH301-705.5 ; Q1-390 ; DNMTs ; n/a ; histone modification ; TBRS ; DNA methyltransferases ; autoinhibition ; epigenetics ; DNMT ; cell identity ; embryogenesis ; dwarfism ; DNMT3B ; germ cells ; HSAN1E ; USP7 ; DNMT3A ; DNA methyltransferase ; gene expression ; DNMT1 ; de novo DNA methylation ; DNA methyltransferase structure ; UHRF1 ; DNA methyltransferase mechanism ; allosteric regulation ; rare diseases ; DNA Methylation ; maintenance DNA methylation ; DNA methylation ; ADCA-DN ; PCC/PGL ; ubiquitination ; TETs ; DNA methyltransferase function ; molecular epigenetics ; DNA methyltransferase regulation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 21
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    Frontiers Media SA
    Publication Date: 2024-03-31
    Description: The main physiological actions of the biologically most active metabolite of vitamin D, 1a,25-dihydroxyvitamin D3(1a,25(OH)2D3), are calcium and phosphorus uptake and transport and thereby controlling bone formation. Other emergent areas of 1a,25(OH)2D3 action are in the control of immune functions, cellular growth and differentiation. This fits both with the widespread expression of the VDR and the above described consequences of vitamin D deficiency. Transcriptome-wide analysis indicated that per cell type between 200 and 600 genes are primary targets of vitamin D. Since most of these genes respond to vitamin D in a cell-specific fashion, the total number of vitamin D targets in the human genome is far higher than 1,000. This is supported by the genome-wide view on VDR binding sites in human lymphocytes, monocytes, colon and hepatic cells. All genomic actions of 1a,25(OH)2D3 are mediated by the transcription factor vitamin D receptor (VDR) that has been the subject of intense study since the 1980’s. Thus, vitamin D signaling primarily implies the molecular actions of the VDR. In this research topic, we present in 15 chapters different perspectives on the action of vitamin D and its receptor, such as the impact of the genomewide distribution of VDR binding loci, ii) the transcriptome- and proteome-wide effects of vitamin D, iii) the role of vitamin D in health, iv) tissue-specific functions of vitamin D and v) the involvement of vitamin D in different diseases, such as infections, autoimmune diseases, diabetes and different types of cancer.
    Keywords: QP1-981 ; Q1-390 ; Vitamin D ; Immune System ; Genomics ; vitamin D receptor ; Physiology ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
    Language: English
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  • 22
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This Special Issue was intended as a forum to advance research and apply machine-learning and data-mining methods to facilitate the development of modern electric power systems, grids and devices, and smart grids and protection devices, as well as to develop tools for more accurate and efficient power system analysis. Conventional signal processing is no longer adequate to extract all the relevant information from distorted signals through filtering, estimation, and detection to facilitate decision-making and control actions. Machine learning algorithms, optimization techniques and efficient numerical algorithms, distributed signal processing, machine learning, data-mining statistical signal detection, and estimation may help to solve contemporary challenges in modern power systems. The increased use of digital information and control technology can improve the grid’s reliability, security, and efficiency; the dynamic optimization of grid operations; demand response; the incorporation of demand-side resources and integration of energy-efficient resources; distribution automation; and the integration of smart appliances and consumer devices. Signal processing offers the tools needed to convert measurement data to information, and to transform information into actionable intelligence. This Special Issue includes fifteen articles, authored by international research teams from several countries.
    Keywords: virtual power plant (VPP) ; power quality (PQ) ; global index ; distributed energy resources (DER) ; energy storage systems (ESS) ; power systems ; long-term assessment ; battery energy storage systems (BESS) ; smart grids ; conducted disturbances ; power quality ; supraharmonics ; 2–150 kHz ; Power Line Communications (PLC) ; intentional emission ; non-intentional emission ; mains signalling ; virtual power plant ; data mining ; clustering ; distributed energy resources ; energy storage systems ; short term conditions ; cluster analysis (CA) ; nonlinear loads ; harmonics, cancellation, and attenuation of harmonics ; waveform distortion ; THDi ; low-voltage networks ; optimization techniques ; different batteries ; off-grid microgrid ; integrated renewable energy system ; cluster analysis ; K-means ; agglomerative ; ANFIS ; fuzzy logic ; induction generator ; MPPT ; neural network ; renewable energy ; variable speed WECS ; wind energy conversion system ; wind energy ; frequency estimation ; spectrum interpolation ; power network disturbances ; COVID-19 ; time-varying reproduction number ; social distancing ; load profile ; demographic characteristic ; household energy consumption ; demand-side management ; energy management ; time series ; Hidden Markov Model ; short-term forecast ; sparse signal decomposition ; supervised dictionary learning ; dictionary impulsion ; singular value decomposition ; discrete cosine transform ; discrete Haar transform ; discrete wavelet transform ; transient stability assessment ; home energy management ; binary-coded genetic algorithms ; optimal power scheduling ; demand response ; Data Injection Attack ; machine learning ; critical infrastructure ; smart grid ; water treatment plant ; power system ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNB Energy industries and utilities
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  • 23
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: This book is motivated by our passion to compile recent research on antimicrobial surfaces. We aimed to assemble research papers on the preparation of new materials, antimicrobial testing using different pathogens (bacteria, fungi, and viruses), and the relationship between the coating nanostructure and its reactivity towards the studied pathogen(s). We believe that a good antimicrobial coating should by characterized by (i) a fast activity towards the pathogen, (ii) sustainable activity based on the stability of the coating, and (iii) the lowest possible toxicity for humans and reduced risks for the environment. Striking a compromise between these different challenges is difficult and requires more research.
    Keywords: active packaging ; chitosan ; methylcellulose ; natamycin ; antimicrobial action ; quaternary ammonium groups ; acrylic acid ; glycidyl methacrylate ; crosslinking reaction ; coating ; edible films ; edible coatings ; antimicrobial agents ; fresh fish ; spoilage ; shelf-life ; black anther disease ; orchid cut flower ; silver nanoparticles ; antifouling efficacy ; flow-through ; triangular box ; Amphibalanus amphitrite ; cuprous oxide ; dynamic aging ; repellant activity ; raft experiment ; bioassay ; biofouling of ships’ hull ; polypropylene ; hernia meshes ; antibacterial ; drug release ; polydopamine ; antimicrobial ; citric acid ; cross-linked ; cold plasma ; antimicrobial activity ; brilliant green ; crystal violet ; demethylation ; lignin ; polyurethane coatings ; triphenylmethane dyes ; 3D printing ; catheters ; dialysis ; extrusion ; infections ; manufacturing ; infection ; coatings ; silver ; nanomaterials ; plasma deposition ; titanium-based thin films ; copper ; magnetron sputtering ; super-elastic coatings ; E. coli inactivation ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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  • 24
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Glial cells are no longer considered passive bystanders in neuronal brain circuits. Not only are they required for housekeeping and brain metabolism, they are active participants in regulating the physiological function and plasticity of brain circuits and the online control of behavior both in invertebrate and vertebrate model systems. In invertebrates, glial cells are essential for normal function of sensory organs (C. elegans) and necessary for the circadian regulation of locomotor activity (D. melanogaster). In the mamallian brain, astrocytes are implicated in the regulation of cortical brain rhythms and sleep homeostasis. Disruption of AMPA receptor function in a subset of glial cell types in mice shows behavioral deficits. Furthermore, genetic disruption of glial cell function can directly control behavioral output. Regulation of ionic gradients by glia can underlie bistability of neurons and can modulate the fidelity of synaptic transmission. Grafting of human glial progenitor cells in mouse forebrain results in human glial chimeric mice with enhanced plasticity and improved behavioral performance, suggesting that astrocytes have evolved to cope with information processing in more complex brains. Taken together, current evidence is strongly suggestive that glial cells are essential contributors to information processing in the brain. This Research Topic compiles recent research that shows how the molecular mechanisms underlying glial cell function can be dissected, reviews their impact on plasticity and behavior across species and presents novel approaches to further probe their function.
    Keywords: RC321-571 ; Q1-390 ; Cerebellum ; C. elegans ; Astrocytes ; DREADD ; Cortex ; plasticity ; Gq ; Behavior ; glia ; Hippocampus ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 25
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The Special Issue “Assessment and Nonlinear Modeling of Wave, Tidal, and Wind Energy Converters and Turbines” contributes original research to stimulate the continuing progress of the offshore renewable energy (ORE) field, with a focus on state-of-the-art numerical approaches developed for the design and analysis of ORE devices. Particularly, this collection provides new methodologies, analytical/numerical tools, and theoretical methods that deal with engineering problems in the ORE field of wave, wind, and current structures. This Special Issue covers a wide range of multidisciplinary aspects, such as the 1) study of generalized interaction wake model systems with elm variation for offshore wind farms; 2) a flower pollination method based on global maximum power point tracking strategy for point-absorbing type wave energy converters; 3) performance optimization of a Kirsten–Boeing turbine using a metamodel based on neural networks coupled with CFD; 4) proposal of a novel semi-submersible floating wind turbine platform composed of inclined columns and multi-segmented mooring lines; 5) reduction of tower fatigue through blade back twist and active pitch-to-stall control strategy for a semi-submersible floating offshore wind turbine; 6) assessment of primary energy conversion of a closed-circuit OWC wave energy converter; 7) development and validation of a wave-to-wire model for two types of OWC wave energy converters; 8) assessment of a hydrokinetic energy converter based on vortex-induced angular oscillations of a cylinder; 9) application of wave-turbulence decomposition methods on a tidal energy site assessment; 10) parametric study for an oscillating water column wave energy conversion system installed on a breakwater; 11) optimal dimensions of a semisubmersible floating platform for a 10 MW wind turbine; 12) fatigue life assessment for power cables floating in offshore wind turbines.
    Keywords: off-shore wind farms (OSWFs) ; wake model ; wind turbine (WT) ; Extreme Learning Machine (ELM) ; wind power (WP) ; large-eddy simulation (LES) ; point-absorbing ; wave energy converter (WEC) ; maximum power point tracking (MPPT) ; flower pollination algorithm (FPA) ; power take-off (PTO) ; hill-climbing method ; Kirsten–Boeing ; vertical axis turbine ; optimization ; neural nets ; Tensorflow ; ANSYS CFX ; metamodeling ; FOWT ; multi-segmented mooring line ; inclined columns ; semi-submersible ; AFWT ; floating offshore wind turbine (FOWT) ; pitch-to-stall ; blade back twist ; tower fore–aft moments ; negative damping ; blade flapwise moment ; tower axial fatigue life ; wave energy ; oscillating water column ; tank testing ; valves ; air compressibility ; air turbine ; wave-to-wire model ; energy harnessing ; energy converter ; flow-induced oscillations ; vortex-induced vibration ; flow–structure interaction ; hydrodynamics ; vortex shedding ; cylinder wake ; tidal energy ; site assessment ; wave-current interaction ; turbulence ; integral length scales ; wave-turbulence decomposition ; OWC ; wave power converting system ; parametric study ; caisson breakwater application ; floating offshore wind turbines ; frequency domain model ; semisubmersible platform ; 10 MW wind turbines ; large floating platform ; platform optimization ; wind energy ; floating offshore wind turbine ; dynamic analysis ; fatigue life assessment ; flexible power cables ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 26
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    IRD Éditions
    Publication Date: 2023-12-20
    Description: Le fleuve Niger constitue un véritable poumon humide pour l’Afrique de l’Ouest et plus spécialement pour la république du Mali. Dans ce pays, la gestion du fleuve constitue un enjeu majeur car on y trouve à la fois de remarquables systèmes de production traditionnels associés au phénomène naturel de crue – sources de moyens d’existence pour des centaines de milliers de personnes – mais aussi de grandes réalisations et promesses en matière d’aménagements modernes, hydroélectriques et hydroagricoles. À l’heure où de nouveaux projets d’équipement arrivent à concrétisation et où d’autres sont annoncés, il est important de faire le point sur l’état de santé de ce fleuve et de peser ce qu’il représente pour ses multiples usagers. Cette expertise collégiale, conduite par l’IRD et l’IER et réalisée avec le soutien de plusieurs institutions d’aide au développement et de défense de l’environnement, traite de ces différents aspects avec pour objectif, d’une part, la clarification des cadres institutionnels et des options de politiques publiques et, d’autre part, le renforcement des outils de suivi et d’aide à la décision.
    Keywords: Q1-390 ; aménagement hydroélectrique ; écosystème ; irrigation ; Niger cours d’eau ; aménagement hydroagricole ; Mali ; exploitation des ressources naturelles ; eau ; bassin versant ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
    Language: French
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  • 27
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Anthropogenic and natural disturbances to freshwater quantity and quality are a greater issue for society than ever before. To successfully restore water resources requires understanding the interactions between hydrology, climate, land use, water quality, ecology, and social and economic pressures. This Special Issue of Water includes cutting edge research broadly addressing investigative areas related to experimental study designs and modeling, freshwater pollutants of concern, and human dimensions of water use and management. Results demonstrate the immense, globally transferable value of the experimental watershed approach, the relevance and critical importance of current integrated studies of pollutants of concern, and the imperative to include human sociological and economic processes in water resources investigations. In spite of the latest progress, as demonstrated in this Special Issue, managers remain insufficiently informed to make the best water resource decisions amidst combined influences of land use change, rapid ongoing human population growth, and changing environmental conditions. There is, thus, a persistent need for further advancements in integrated and interdisciplinary research to improve the scientific understanding, management, and future sustainability of water resources.
    Keywords: physical habitat ; aquatic ecology ; stream health ; environmental flows ; land use ; hydrology ; hydroecology ; ecohydrology ; climate change ; Appalachia ; reforestation ; land use-land cover ; land-atmosphere coupling ; water quality ; environmental perceptions ; human dimensions ; spatial models ; socioeconomics ; urban watershed management ; municipal watershed ; water quality impairment ; collaborative adaptive management ; water resources ; urban watersheds ; endocrine disrupting chemical ; opioid ; pathway analysis ; ontology ; metabolomics ; decision-making ; logit regression ; farmer perceptions ; social networks ; public funds ; water conservation adoption ; good governance ; sanitation ; sustainability ; water supply ; water-saving agriculture ; Chinese provincial input efficiency ; three-stage DEA model ; environmental variables ; Boufakrane river watershed ; remote sensing ; LULCC ; water balances ; vulnerability ; total dissolved solids ; drinking water ; Appalachian Mountains ; streamflow sensitivity ; water security ; water balance partitioning ; Budyko ; Escherichia coli ; Suspended particulate matter ; Water quality ; Land use practices ; Watershed management ; basin ; hydrologic model ; reaeration rates ; stream metabolism ; watershed ; physicochemistry ; land use practices ; experimental watershed ; suspended particulate matter ; stream water temperature ; watershed management ; bacteria ; land-use practices ; environmental persistence ; saturated hydraulic conductivity ; pedotransfer function ; model validation ; Chesapeake Bay Watershed ; experimental watershed study ; human dimensions of water ; watershed modeling ; hydrological modeling ; water pollutants ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 28
    Publication Date: 2024-03-27
    Description: This Special Issue provides an insight, collated from 26 articles, focusing on various aspects of the Fit-For-Purpose Land Administration (FFPLA) concept and its application. It presents some influential and innovative trends and recommendations for designing, implementing, maintaining and further developing Fit-For-Purpose solutions for providing secure land rights at scale. The first group of 14 articles is published in Volume One and discusses various conceptual innovations related to spatial, legal and institutional aspects and its wider applications within land use management. The second group of 12 articles is published in Volume Two and focuses on case studies from various countries throughout the world, providing evidence and lessons learned from the FFPLA implementation process.
    Keywords: complete cadastre ; legal element ; fixing boundary ; eligible landowner ; agreement ; boundary marker ; fit-for-purpose land administration (FFP LA) ; violent conflict ; United Nations ; extra-legal ; transitional justice ; peace building ; land governance ; power relations ; securing land rights ; land registration ; development impacts ; fit-for-purpose land administration ; land administration ; decentralization ; India ; fit-for-purpose ; institutions ; governance ; politics ; Amazon ; deforestation ; Fit-For-Purpose land administration ; participatory mapping ; indigenous land conflict ; Cumaribo ; Colombia ; community-based land adjudication ; components of adjudication ; land tenure ; land rights ; good practices ; updating land records ; systematic land registration ; unconventional approach ; case study ; Benin ; cadaster ; land administration domain model ; LADM ; cadastre ; FFPLA ; customary tenure ; land inventory ; land management ; mobile-based applications ; pro-poor ; land surveying ; tenure security ; land rights and tenure ; fit-for-purpose approach ; human rights ; design science research ; design thinking ; fit for purpose ; spatial data quality ; spatial data quality assurance ; maintenance ; update ; upgrade ; upkeep ; renewal ; data quality ; spatial framework ; STDM ; technology ; UAV ; feature extraction ; rapid urbanization ; climate change ; pandemic ; urban resilience ; spatial ; legal ; and institutional frameworks ; land tenure security ; pro-poor land recordation ; land governance reform ; cost effectiveness ; innovative technology ; case studies ; Uganda ; customary land tenure ; land recordation tools ; semantic technologies ; land information system ; fit-for-purpose land management ; aerial and street level imagery ; machine learning ; integrated land programs ; land policy ; pilot study ; informal settlements ; urban development ; Brazil ; community-based crowdsourcing ; SiGIT ; Ecuador ; land and resources rights ; public-private partnerships ; corporate social responsibility ; poverty reduction ; business driven solutions ; social enterprises ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
    Language: English
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  • 29
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The fundamentals of mechanical system dynamics were established before the beginning of the industrial era. The 18th century was a very important time for science and was characterized by the development of classical mechanics. This development progressed in the 19th century, and new, important applications related to industrialization were found and studied. The development of computers in the 20th century revolutionized mechanical system dynamics owing to the development of numerical simulation. We are now in the presence of the fourth industrial revolution. Mechanical systems are increasingly integrated with electrical, fluidic, and electronic systems, and the industrial environment has become characterized by the cyber-physical systems of industry 4.0. Within this framework, the status-of-the-art has become represented by integrated mechanical systems and supported by accurate dynamic models able to predict their dynamic behavior. Therefore, mechanical systems dynamics will play a central role in forthcoming years. This Special Issue aims to disseminate the latest research findings and ideas in the field of mechanical systems dynamics, with particular emphasis on novel trends and applications.
    Keywords: tire model ; tire temperature ; FSAE vehicle ; rolling bearing ; rigid rotor ; internal radial clearance ; number of rolling elements ; vibration ; varying compliance vibration ; ball passage frequency ; load ; trucks ; handling stability ; lightweight ; taper-leaf spring ; suspension ; step steer ; motorcycle tires ; thermal modeling ; performance optimization ; real-time simulations ; conveyor ; friction ; rolling ; non-linear simulation ; fractal derivative ; viscoelastic models ; polymers ; bicycle ; mountain bike ; tire tread pattern ; force and moment ; e-bike ; tyre ; dynamics ; active rear axle independent steering (ARIS) system ; hierarchical synchronization control ; virtual coupling control ; linear active disturbance rejection control (LADRC) ; computational fluid dynamics ; fluid sloshing ; table cart method ; zero moment point ; rider ; body segment inertial parameters ; biomechanics ; human body ; motorcycle ; multibody ; robot ; compliance ; machining ; modes of vibration ; impulsive testing ; dynamic parameter identification ; dynamic parameters ; parallel kinematics ; parallel robot ; parallel manipulator ; varying friction ; valve train ; coupled approach ; NVH ; vibration energy control ; multi-physics mechanism theory ; non-linear stiffness ; isolation ; hydraulic system ; magnetic spring ; articulated vehicle ; hydraulic steering system ; directional stability ; deformable soil ; tracked vehicle ; contact model ; two-wheeler ; vehicle dynamic modelling ; wobble ; weave ; fork bending compliance ; rider influence ; ADAS ; driver model ; load cell ; steering wheel ; cable robots ; motion planning ; cable failure ; recovery strategy ; roller chain ; chain efficiency ; sliding friction ; lateral offset ; damping force ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 30
    Publication Date: 2024-04-05
    Description: Newborn Screening for Sickle Cell Disease and other Haemoglobinopathies is a Special Issue of the International Journal of Neonatal Screening. Sickle cell disease is one of the most common inherited blood disorders, with a huge impact on health care systems due to high morbidity and high mortality associated with the undiagnosed disease. Newborn screening helps to make the diagnosis early and to prevent fatal complications and diagnostic odysseys. This book gives an overview of diagnostic standards in newborn screening for sickle cell disease and examples of existing newborn screening programs.
    Keywords: QD1-999 ; Q1-390 ; glucose-6-phosphate dehydrogenase ; hydroxyurea/hydroxycarbamide ; n/a ; cord blood ; screening ; hemoglobin pattern ; capillary electrophoresis ; sickle cell disease ; (recommended) screening panel ; vaso-occlusive crisis ; Guthrie spots ; newborn screening) ; foetal haemoglobin ; harmonisation ; review ; birth prevalence ; G6PD deficiency ; prevention ; end-organ damage ; thalassemia ; MALDI-TOF ; IEF ; acute chest syndrome ; India ; sickle cell and thalassaemia screening programme ; ‘Getting to Outcomes’ ; newborn screening ; hemoglobinopathy ; service users ; public health engagement ; automated HPLC ; Kaduna State ; gene therapy for haemoglobinopathies ; ?-globin gene ; methods ; neonatal screening program ; malaria ; Plasmodium vivax ; sub-Saharan Africa ; patient organisations ; health policy ; pathophysiology ; Sickle Cell Disease ; mass spectrometry ; sickle cell disorder ; neonatal screening ; non-tribal ; Nigeria ; point-of-care ; HPLC ; laboratory methods ; registry ; patient advocacy ; bone marrow transplant ; anaemia ; hemoglobinopathies ; tribal ; newborn ; burden of disease ; patient representatives ; diagnostics ; policy making ; haemolysis ; Caribbean ; high performance liquid chromatography (HPLC) ; sickle cell disease (SCD) ; implementation science ; thema EDItEUR::P Mathematics and Science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Supply Chain 4.0 is designed, planned, managed and optimized using Industry 4.0 technologies. There are many research issues and challenges associated with Supply Chain 4.0, a data rich complex system. The available data can interpret what happened in the past, what is currently happening, what will happen in the future and what are the best actionable decisions. Digitalization, visibility, connectivity and interoperability are integrated in Supply Chain 4.0. The operational, tactical and strategic plans across the supply chain are digitally interlinked and real-time synchronized with a 360-degree view. The win–win partnerships are dynamic and sustainable, with agility, flexibility and responsiveness to uncertain business environments. New models and methods are advocated to implement Supply Chain 4.0 research and development. With the progress and implementation of Industry 4.0 technologies, it is anticipated that there will be more and more breakthroughs in the models and methods of Supply Chain 4.0. This Special Issue will serve as a helpful reference for Supply Chain 4.0 researchers and practitioners.
    Keywords: Industry 4.0 ; supply chain management and optimization ; Supply Chain 4.0 ; supply chain analytics ; supply chain visibility and connectivity ; supply chain synchronization and coordination ; sustainable supply chain management&nbsp ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 32
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Additive manufacturing (AM) processes are gaining more and more attention from many industrial fields, mainly because they are revolutionizing the components’ designs and production lines. The complete industrialization of these processes has to be supported by the full understanding of correlation between AM building conditions and the final materials’ properties. Another critical aspect is that nowadays only a reduced number of materials processable by AM are available on the market. It is, therefore, fundamental to widen the materials’ portfolio, and to study and develop new materials that can take advantage of these unique building processes.
    Keywords: amorphous poly(lactide acid) ; poly(styrene-co-methyl methacrylate) ; polymer blends ; filament extrusion ; 3D printing ; additive manufacturing ; silicon nitride ; high performance ceramics ; photopolymerisation ; lithography-based ceramic manufacturing ; fused-deposition modeling ; mechanical properties ; thermal behavior ; polyetherimide ; fused filament modelling ; design of experiments ; directed energy deposition ; AISI 316L ; microstructure ; LPBF ; as-built ; as-cast ; microhardness ; tensile test ; Ni–Cu alloy ; materials development ; polymers ; metals ; ceramics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 33
    Publication Date: 2024-04-11
    Description: This Special Issue covers symmetry and asymmetry phenomena occurring in real-life problems. We invited authors to submit their theoretical or experimental research presenting engineering and economic problem solution models dealing with the symmetry or asymmetry of different types of information. The issue gained interest in the research community and received many submissions. After rigorous scientific evaluation by editors and reviewers, nine papers were accepted and published. The authors proposed different MADM and MODM solution models as integrated tools to find a balance between the components of sustainable global development, to find a symmetry axis concerning goals, risks, and constraints to cope with the complicated problems. Most approaches suggested decision models under uncertainty, combining the usual decision-making methods with interval-valued fuzzy or rough sets theory, also Z numbers. The application fields of the proposed models involved both problems of technological sciences and social sciences. The papers cover three essential areas: engineering, economy, and management. We hope that a summary of the Special Issue as provided here will encourage a detailed analysis of the papers included in the Printed Edition.
    Keywords: TA1-2040 ; T1-995 ; rough sets ; interval type-2 fuzzy set (IT2FS) ; resources distribution ; the criteria of the weights ; public management ; Step-wise Weight Assessment Ratio Analysis (SWARA) ; multi-criteria decision-making (MCDM) ; symmetry of the method ; quadcopter ; transaction cost ; full fuzzy environment ; dual generalized geometric Bonferroni mean (DGGBM) operator ; data logger ; information theory ; control system ; salvage value ; nonlinear dynamics ; pattern formation ; oscillations ; stability ; Pythagorean fuzzy set ; FAHP ; fuzzy sets ; group decision-making ; generalized Bonferroni mean (GBM) operator ; probabilistic systems analysis ; economic decisions ; 2-tuple linguistic neutrosophic numbers set (2TLNNSs) ; evaluating the quality of distant courses ; subjective weights ; Z-numbers ; green supplier selection ; dual generalized Bonferroni mean (DGBM) operator ; normal cloud ; thrust ; sensor ; neutrosophic numbers ; MCDM ; Bayes’ theorem ; optimal dividend ; logistics ; measurement ; hybrid MCDM ; combining the weights ; data envelopment analysis ; criteria weights ; multiple attribute decision making (MADM) ; IDOCRIW ; excess-of-loss reinsurance ; fuzzy efficiency ; multiple-criteria decision-making (MCDM) ; MCGDM ; transport ; backward cloud transformation ; engineering problems ; rough ARAS ; capital injection ; performance ; Bonferroni mean (BM) operator ; green supply chain management ; population sizes ; hybrid problem solution models ; criteria weight assessment ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 34
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: During cell metabolism, oxygen is partially reduced to reactive oxygen species (ROS) that play a physiological role in cellular processes. However, an imbalance between the production of ROS and the ability of defenses to detoxify the organism provokes oxidative stress. Oxidative stress and its subsequent damages to vital cellular components have been associated with numerous severe chronic disorders. In addition, oxidation reactions are responsible for food deterioration during processing and storage. Peptides from animal and vegetal food sources have attracted attention due to the large evidence of their in vitro antioxidant properties. In addition to their potential as safer alternatives to synthetic antioxidants used to prevent oxidative reactions in foods, antioxidant peptides can also act by reducing the risk of numerous oxidative stress-associated diseases. Furthermore, peptides can act synergistically with nonpeptide antioxidants, enhancing their protective effect. This Special Issue of the Foods journal includes outstanding papers illustrating examples of the most recent advances on antioxidant peptides from both vegetal and animal sources. The existing data on their bioactivities demonstrated by in silico, in vitro, and animal models are included as well as the mechanisms of action of identified antioxidant peptides.
    Keywords: food peptides ; reactive oxygen species ; antioxidant enzymes ; whey protein hydrolysate ; hydrolysis condition ; food antioxidant ; ORAC ; cellular ROS ; HepG2 ; peptides ; egg white ; egg yolk ; antioxidant peptides ; sarcopenia ; whey protein ; muscle ; C2C12 ; aged animals ; older adult ; exercise ; bioactive peptides ; animal protein ; multifunctionality ; antioxidant activity ; in silico ; cell models ; fruit residues ; antioxidant ; extraction ; albumin ; albumin peptide ; antioxidant peptide ; bioactive peptide ; mung bean ; mung bean albumin ; peptide sequencing ; Vigna radiata ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 35
    Publication Date: 2024-04-05
    Description: In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and neural dynamics in humans. A growing body of evidence indicates that the neural dynamics (e.g., oscillations, synchrony) are important in mediating information processing and networking for various functions in the human brain. Most of previous studies on human brain dynamics, however, show correlative relationships between brain functions and patterns of neural dynamics measured by imaging methods such as electroencephalography (EEG), magnetoencephalography (MEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). In contrast, manipulative approaches by non-invasive brain stimulation (NIBS) have been developed and extensively used. These approaches include transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) such as transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), and random noise stimulation (tRNS), which can directly manipulate neural dynamics in the intact human brain. Although the neural-correlate approach is a strong tool, we think that manipulative approaches have far greater potential to show causal roles of neural dynamics in human brain functions. There have been technical challenges with using manipulative methods together with imaging methods. However, thanks to recent technical developments, it has become possible to use combined methods such as TMS–EEG coregistration. We can now directly measure and manipulate neural dynamics and analyze functional consequences to show causal roles of neural dynamics in various brain functions. Moreover, these combined methods can probe brain excitability, plasticity and cortical networking associated with information processing in the intact human brain. The contributors to this EBook have succeeded in showcasing cutting-edge studies and demonstrate the huge impact of their approaches on many areas in human neuroscience and clinical applications.
    Keywords: RC321-571 ; Q1-390 ; non-invasive brain stimulation NIBS ; TMS-EEG ; Transcranial magnetic stimulation TMS ; transcranial electric stimulation tES ; Coregistration ; Near-infrared spectroscopy NIRS ; Functional magnetic resonance imaging fMRI ; transcranial direct current stimulation tDCS ; transcranial alternating current stimulation tACS ; transcranial random noise stimulation tRNS ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 36
    Publication Date: 2024-04-05
    Description: Bálint’s syndrome is named after the Hungarian physician who first reported a remarkable case of a man with complex visuospatial deficits following bilateral lesions within parietal and occipital cortex (Bálint, 1909). The syndrome has three primary symptoms: simultanagnosia (impaired spatial awareness of more than one object at time), optic ataxia (misreaching to visual targets) and ocular apraxia (described by Bálint as “psychic paralysis of gaze”). Balint’s patients not only cannot perceive more than one object at time and therefore show poor comprehension of multi-object visual scenes i.e. poor detection of all the objects present and difficulty in grasping the relationship between them; in addition they typically fail to reach towards location of the single object, which they can perceive. The deficit of the allocation of spatial attention in Balint’s syndrome has been linked to a problem in feature binding which results in illusory conjunctions. Patients with Balint’s syndrome also show deficits in global processing i.e. when integration of multiple local elements into global compound shapes is required. Consequently, Balint’s syndrome provides a unique opportunity to study the nature and neuroanatomy of human visuospatial processing, in particular multi-level object representation, spatial awareness and the distribution of visual attention. The studies collected here cover both the anatomical and the cognitive mechanisms of the different symptoms associated with the syndrome. Furthermore, the dissociations between the components of Bálints’ syndrome, in particular simultanagnosia and optic ataxia, can also co-occur with visual neglect and extinction and the different combinations of reported lesions raises a question about the status of the syndrome and whether it should be merely treated as a historical compilation of symptoms which may or may not coexist cohesively. This interesting argument is raised here.
    Keywords: RC321-571 ; Q1-390 ; posterior cortical atrophy ; Balints syndrome ; optic ataxia ; Posterior parietal cortex ; simultanagnosia ; ocular apraxia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 37
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The proliferation of powerful but cheap devices, together with the availability of a plethora of wireless technologies, has pushed for the spread of the Wireless Internet of Things (WIoT), which is typically much more heterogeneous, dynamic, and general-purpose if compared with the traditional IoT. The WIoT is characterized by the dynamic interaction of traditional infrastructure-side devices, e.g., sensors and actuators, provided by municipalities in Smart City infrastructures, and other portable and more opportunistic ones, such as mobile smartphones, opportunistically integrated to dynamically extend and enhance the WIoT environment. A key enabler of this vision is the advancement of software and middleware technologies in various mobile-related sectors, ranging from the effective synergic management of wireless communications to mobility/adaptivity support in operating systems and differentiated integration and management of devices with heterogeneous capabilities in middleware, from horizontal support to crowdsourcing in different application domains to dynamic offloading to cloud resources, only to mention a few. The book presents state-of-the-art contributions in the articulated WIoT area by providing novel insights about the development and adoption of middleware solutions to enable the WIoT vision in a wide spectrum of heterogeneous scenarios, ranging from industrial environments to educational devices. The presented solutions provide readers with differentiated point of views, by demonstrating how the WIoT vision can be applied to several aspects of our daily life in a pervasive manner.
    Keywords: TA1-2040 ; T1-995 ; container ; fog computing ; virtual reality ; privacy and security ; software defined infrastructure ; intelligent medical service ; very long instruction word (VLIW) ; semantics ; privacy leakage detection ; context information ; post-copy ; ontology ; body area network ; DSP ; Internet-of-Things ; Mobile Device Management ; interoperability ; Android ; water consumption ; Processing-in-Memory ; performance analysis ; semantic ; mobility ; data management ; CRIU ; training simulator ; Industry 4.0 ; sensor networks ; experimental evaluation ; programming paradigm ; pre-copy ; microservice-oriented platform ; CubeSats ; middleware ; registry ; smart metering ; big data analytics ; nanosatellites ; medium access control ; Internet of Things ; heterogeneity ; web-of-things ; one-to-one computing educational program ; Web-of-Things ; internet of things ; instruction set extension ; microservices architecture ; migration ; behaviour ; wireless access networks ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: As an important tool of systems biology, proteomics has enabled a deep understanding of different plant processes and functions. Complemented with genomic data, computational tools, and improved sample preparation strategies, proteomics has an unprecedented opportunity to characterize plant proteoforms in high spatial and temporal resolution. This special issue of Plant Proteomic Research 4.0 captures the recent advancements in proteomics and addresses the current challenges of plant stress response and resilience in the ever-changing climate. It contains 12 articles, including three reviews and nine original research articles. The three reviews deal with pollen phosphoproteomics, starch biosynthesis-related proteins and posttranslational modifications (PTMs) in rice developing seeds, and PTMs of waxy proteins in rice grain. The nine research articles include three related to temperature, two on water stress, two on salt stress, one on fungal pathogen, and the last one on field-grown potato apoplast proteome. The articles reflect the current frontiers of plant proteomics, focusing on themes of environmental stresses, proteoforms/PTMs, crop species, and new development in data-independent acquisition mass spectrometry. They provide readers insights into current technologies, their utility in understanding plant growth and resilience, as well as directions of proteomics in the frontiers of systems biology and synthetic biology.
    Keywords: peptide markers ; Quercus ilex ; drought tolerance ; targeted post-acquisition proteomics ; plant pathogenesis responses ; quantitative proteomics ; data-independent acquisition ; Phytophthora infestans ; waxy ; amylose ; posttranslational modification ; GBSSI ; rice ; wheat ; salt stress ; physiological characteristics ; ER proteome ; label-free quantitation ; starch biosynthesis ; proteomics ; starch functionality ; cooking and eating quality ; Mesembryanthemum crystallinum ; McHB7 ; transcription factor ; late embryogenesis abundant ; Arabidopsis ; seed germination ; metabolomics ; heat-stable proteome ; dehydrins ; LEA transcripts ; intrinsically disordered proteins ; floral thermogenesis ; Nelumbo nucifera ; DIA-based quantitative proteomics ; time series analysis ; protein-protein interaction network ; WGCNA ; mutant soybean ; flooding ; glycoprotein folding ; fermentation ; cell death ; rice endosperm ; phosphorylation ; high temperature ; sucrose and starch metabolism ; ABPP ; apoplast ; serine hydrolases ; β-glycosidases ; potato ; field-omics ; phosphoproteomics ; pollen tube ; male gametophyte ; root hair ; signal transduction ; kinase motif ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 39
    Publication Date: 2024-04-05
    Description: The tale of cyclic GMP has been astonishing. Having overcome an initial disbelief, cyclic GMP has risen to its present eminence as a premium cellular signal transduction messenger of not only hormonal extracellular but also of the intracellular signals. This research topic focuses on the pathways and functions of membrane guanylate cyclases in different tissues of the body and their interplay with intracellular sensory signals where in many cases, cyclic GMP along with Ca2+ have taken on roles as synarchic co-messengers.
    Keywords: RC321-571 ; Q1-390 ; Glaucoma ; Visceral Pain ; Calcium ; membrane guanylate cyclase ; ANF-RGC ; Gene Therapy ; Cyclic GMP ; synaptic plasticity ; trafficking ; ROS-GC ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 40
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Photoacoustic (or optoacoustic) imaging, including photoacoustic tomography (PAT) and photoacoustic microscopy (PAM), is an emerging imaging modality with great clinical potential. PAI’s deep tissue penetration and fine spatial resolution also hold great promise for visualizing physiology and pathology at the molecular level. PAI combines optical contrast with ultrasonic resolution, and is capable of imaging at depths of up to 7 cm with a real-time scalable spatial resolution of 10 to 500 µm. PAI has demonstrated applications in brain imaging and cancer imaging, such as breast cancer, prostate cancer, ovarian cancer etc. This Special Issue focuses on the novel technological developments and pre-clinical and clinical biomedical applications of PAI. Topics include but are not limited to: brain imaging; cancer imaging; image reconstruction; quantitative imaging; light source and delivery for PAI; photoacoustic detectors; nanoparticles designed for PAI; photoacoustic molecular imaging; photoacoustic spectroscopy.
    Keywords: photoacoustic imaging ; tomography ; thermoacoustic ; radio frequency ; image quality assessment ; image formation theory ; image reconstruction techniques ; sparsity ; signal processing ; deconvolution ; empirical mode decomposition ; signal deconvolution ; photoacoustics ; tissue characterization ; absorption ; Photoacoustic Computed Tomography (PACT) ; ring array ; fast imaging ; low cost ; photoacoustic tomography ; full-field detection ; wave equation ; final time inversion ; uniqueness ; stability ; iterative reconstruction ; 3D photoacoustic tomography ; full-view illumination and ultrasound detection ; photoacoustic coplanar ; quartz bowl ; correlation matrix filter ; time reversal operator ; photo-acoustic tomography ; reflection artifacts ; deep learning ; convolutional neural network ; time reversal ; Landweber algorithm ; U-net ; optoacoustic imaging ; respiratory gating ; motion artifacts ; full-ring illumination ; diffused-beam illumination ; point source illumination ; ultrasound tomography (UST) ; photoacoustic tomography (PAT) ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 41
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: Introducing “A Feasible Approach for Natural Products to Treatment of Diseases”–an exploration of the therapeutic potential locked within nature’s abundant offerings. This comprehensive reprint delves into the fascinating realm of natural products, uncovering their inherent properties, mechanisms of action, and potential roles in effective disease management. Through extensive scientific research and reviews, the authors shed light on the immense potential of natural products as a viable approach to enhancing health and combating diseases. This reprint presents a diverse and multidimensional exploration, bridging the gap between traditional wisdom and contemporary scientific understanding and offering new avenues for healthcare professionals, researchers, and enthusiasts to harness the power of nature’s remarkable resources. As a catalyst for unlocking the healing potential of natural products, this reprint inspires further investigation and innovation, and drives us towards a future where their integration into mainstream healthcare becomes indispensable. Discover the possibilities and embark on a health and well-being journey with “A Feasible Approach for Natural Products to Treatment of Diseases”.
    Keywords: cancer immunotherapy ; fructan ; FT-IR ; mass spectrometry ; young green barley ; COVID-19 ; β-glucans ; immunomodulation ; anti-inflammation ; anti-oxidant ; ACE2 regulation ; impedance ; ECIS ; antitumor activity ; anticancer properties ; betulin ; betulinic acid ; Amadori rearrangement compounds ; barley ; anti-obesity ; arginyl-fructose ; adipogenic ; ergosta-5,7,22,24(28)-tetraenol (ERGT) ; cholesta-5,7,22,24-tetraenol (CHT) ; ergosterol biosynthesis ; antimetabolite ; suicide substrate ; Trypanosoma brucei ; coronavirus SARS-CoV-2 ; main protease ; Saussurea costus ; molecular docking ; GC-MS profiling ; Molineria recurvata ; diabetic nephropathy ; urinary biomarkers ; inflammation ; oxidative stress ; walnut ; Juglans regia ; high-fat diet ; insulin resistance ; cognitive function ; JNK/NFκB pathway ; Citri Reticulatae Pericarpium ; flavonoids ; anticancer ; mechanism ; phenotype ; Angelica sinensis polysaccharide ; Astragalus membranaceus polysaccharide ; hexokinase 2 ; glycolysis ; JAK2/STAT3 pathway ; liver regeneration ; Holoptelea integrifolia ; MMP-9 ; wound healing ; friedelin ; oxalactam A ; macrolactam ; anti-Rhizoctonia solani ; Penicillium oxalicum ; molecular dynamics ; non-alcoholic fatty liver disease (NAFLD) ; natural products ; terpenoids ; mechanisms ; treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 42
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: In recent years, inorganic oxidic nanomaterials have been extensively investigated for their outstanding properties that allow their use within a large variety of raising fields of interest, ranging from (photo)catalysis to the development of functional nanocomposites. Nanoscopic metal (eventually mixed) oxides are often fabricated following soft-chemistry approaches, characterized by the possibility of favouring specific morphologies, particles dimensions, and surface porosities through different synthetic methods and templating processes. In this context, surface functionalities and reactivity play a major role in the determination of nanomaterials final properties. For this reason, further surface functionalization with specific chemical moieties is often recommended to extend their field of application. This Special Issue, now edited as a book, aimed at extending the comprehension of the mechanisms involved in the synthesis and templating of inorganic oxidic nanomaterials, as well as in their surface functionalization and reactivity. Additionally, this Special Issue aimed at increasing the knowledge on the latest advances of these systems in (photo)catalysis, environmental clean-up processes, energy storage, controlled transport and/or release, biomedicine, sensing, development of smart-materials, stimuli-responsive materials, and nanocomposites. Nanomaterials of interest included: silica, alumina, titania, zirconia, zinc oxide, aluminosilicates, iron oxides, perovskites and titanates, rare earth oxides, and composites. Furthermore, particular attention was dedicated toward studies describing alternative ecofriendly preparation methods.
    Keywords: alumino-silicates ; biomedicine ; ceramics ; clays ; inorganic chemistry ; environmental remediation ; nanomaterials ; porous materials ; mesoporous material ; zero-valent-iron nanoparticles ; methylene blue adsorption ; metal–organic framework ; iridium oxide ; nanostructuration ; IrO2 applications ; IrO2 synthesis ; OER ; C3N4 ; ZnO ; heterojunction ; photocatalyst ; metal oxide nanocomposites ; microstructural analysis ; electrospinning ; polymer substrate ; photodegradation ; LSA 99Mo ; thermodynamic parameters ; solid-phase extraction ; isotherm ; metal oxides NPs ; Ni-Fe-TiO2 nanocomposite ; microstructure ; biocompatibility ; endodontic file ; graphitic carbon nitride ; photocatalysts ; g-C3N4/ZnO ; visible light ; photocatalytic degradation ; inorganic coatings ; functional coatings ; stimuli-responsive polymers ; sol–gel ; antimicrobial ; wear-resistance ; photo-catalytic activity ; UV protection ; calcium oxide-doped carbon nitride nanostructures ; basic fuchsine ; elimination mechanism ; π-π stacking ; magnetic nanoparticles ; magnetite ; solvothermal synthesis ; waste valorization ; green chemistry ; advanced oxidation processes ; experimental protocols ; heterogeneous catalysis ; inorganic thermal activation ; organic pollutants ; perovskites ; physico-chemical characterization ; solution combustion synthesis ; strontium ferrates ; water treatment ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PN Chemistry ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNK Inorganic chemistry
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  • 43
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The sustainability of water resources worldwide is increasingly imperiled as climate change contributes to the human-induced problems of water supply scarcity and maldistribution. Environmental problems associated with water quality, such as aquifer depletion, land subsidence, the seasonal drying of river flows, waterlogging, the salinization of rivers and groundwater, and human health problems from the excessive use of fertilizers and pesticides will require a radical re-thinking of resource-management policy and new tools to help analysts and regulators craft novel solutions. Over the past several decades, with the advent and rapid progress of computational technology, watershed models have increasingly become important and effective tools for tackling a wide range of water resource and environmental management issues and for supporting regulatory compliance. Statistical and machine-learning methods are being used to support and even supplant more traditional simulation models to improve the estimation of the temporal dynamics and patterns of variability in pollutant concentrations and loads. With the advancements in modeling approaches for water quality, there have also been developments in decision-support tools for water quality management. This reprint describes innovative decision-support approaches from around the world and across sectors that can be applied by stakeholders, government entities, and regulators to reduce environmental pollution and result in cost-effective and sustainable water management strategies.
    Keywords: tree-ring ; flow reconstruction ; pre-development ; estuarine salinity ; salinity intrusion ; water quality forecasting ; decision support ; WARMF ; regression model ; salinity ; irrigated agriculture ; stakeholder involvement ; stream water quality ; CART ; ID3 ; random forest ; bagging ; boosting ; extremely random trees ; Gradient Boosting ; land use factor ; Decision Support System ; water quality forecast ; MLP neural network ; Daubechies 5 wavelet ; long short-term memory network ; hybrid model ; decomposition-and-ensemble ; CE-QUAL-W2 ; EDSS ; SaaS ; irrigation ; agriculture ; policy ; water ; economics ; model ; conservation practices ; decision making ; nutrients ; sediment ; targeting ; water quality ; chemical footprint ; emerging contaminants ; endocrine-disrupting compounds ; footprint calculator ; personal care products ; remote sensing ; geographical information systems ; watershed management ; ambient monitoring ; data collection ; San Joaquin River ; decision support system ; assimilative capacity ; real-time management economics ; drinking water quality ; operational decision-making ; real-time monitoring ; Sacramento-San Joaquin Delta ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::K Economics, Finance, Business and Management::KC Economics::KCV Economics of specific sectors::KCVG Environmental economics ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology::TQK Pollution control
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  • 44
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Our world is facing many challenges, such as poverty, hunger, resource shortage, environmental degradation, climate change, and increased inequalities and conflicts. To address such challenges, the United Nations proposed the Sustainable Development Goals (SDG), consisting of 17 interlinked global goals, as the strategic blueprint of world sustainable development. Nevertheless, the implementation of the SDG framework has been very challenging and the COVID-19 pandemic has further impeded the SDG implementation progress. Accelerated efforts are needed to enable all stakeholders, ranging from national and local governments, civil society, private sector, academia and youth, to contribute to addressing this dilemma. This volume of the Climate Change and Environmental Sustainability book series aims to offer inspiration and creativity on approaches to sustainable development. Among other things, it covers topics of COVID-19 and sustainability, environmental pollution, food production, clean energy, low-carbon transport promotion, and strategic governance for sustainable initiatives. This book can reveal facts about the challenges we are facing on the one hand and provide a better understanding of drivers, barriers, and motivations to achieve a better and more sustainable future for all on the other. Research presented in this volume can provide different stakeholders, including planners and policy makers, with better solutions for the implementation of SDGs. Prof. Bao-Jie He acknowledges the Project NO. 2021CDJQY-004 supported by the Fundamental Research Funds for the Central Universities. We appreciate the assistance from Mr. Lifeng Xiong, Mr. Wei Wang, Ms. Xueke Chen and Ms. Anxian Chen at School of Architecture and Urban Planning, Chongqing University, China.
    Keywords: climate change ; sustainable development goals ; urban transformation ; decarbonization ; built environment ; governance ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 45
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Research on radiation-tolerant electronics has increased rapidly over the past few years, resulting in many interesting approaches to modeling radiation effects and designing radiation-hardened integrated circuits and embedded systems. This research is strongly driven by the growing need for radiation-hardened electronics for space applications, high-energy physics experiments such as those on the Large Hadron Collider at CERN, and many terrestrial nuclear applications including nuclear energy and nuclear safety. With the progressive scaling of integrated circuit technologies and the growing complexity of electronic systems, their susceptibility to ionizing radiation has raised many exciting challenges, which are expected to drive research in the coming decade. In this book we highlight recent breakthroughs in the study of radiation effects in advanced semiconductor devices, as well as in high-performance analog, mixed signal, RF, and digital integrated circuits. We also focus on advances in embedded radiation hardening in both FPGA and microcontroller systems and apply radiation-hardened embedded systems for cryptography and image processing, targeting space applications.
    Keywords: TA1-2040 ; TK1-9971 ; T1-995 ; single event effects ; n/a ; radiation-hardening-by-design (RHBD) ; frequency divider by two ; single event upset ; Image processing ; CMOS analog integrated circuits ; FPGA ; total ionizing dose (TID) ; Impulse Sensitive Function ; soft error ; hardening by design ; radiation hardening by design ; X-rays ; Single-Event Upsets (SEUs) ; line buffer ; heavy ions ; VHDL ; FPGA-based digital controller ; radiation hardening by design (RHBD) ; radiation hardening ; SRAM-based FPGA ; proton irradiation ; ring oscillator ; sensor readout IC ; fault tolerance ; space application ; physical unclonable function ; voltage controlled oscillator (VCO) ; Ring Oscillators ; analog single-event transient (ASET) ; single event opset (SEU) ; SEB ; single event upsets ; bipolar transistor ; total ionizing dose ; protons ; triple modular redundancy (TMR) ; gain degradation ; space electronics ; saturation effect ; configuration memory ; Co-60 gamma radiation ; total ionization dose (TID) ; frequency synthesizers ; CMOS ; PLL ; TDC ; single-event upsets (SEUs) ; bandgap voltage reference (BGR) ; 4MR ; single-shot ; error rates ; Radiation Hardening by Design ; soft errors ; heavy-ions ; single-event effects (SEE) ; single event transient (SET) ; SEE testing ; proton irradiation effects ; RFIC ; single event upset (SEU) ; FMR ; ionization ; radiation tolerant ; triplex–duplex ; neutron irradiation effects ; digital integrated circuits ; single event gate rupture (SEGR) ; power MOSFETs ; ring-oscillator ; selective hardening ; voltage reference ; nuclear fusion ; TMR ; gamma-rays ; gamma ray ; instrumentation amplifier ; radiation effects ; reference circuits ; radiation-hardened ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 46
    Publication Date: 2024-04-05
    Description: In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system.
    Keywords: RC321-571 ; Q1-390 ; Nervous System ; Ion Channels ; Interactome ; cellular signaling ; Protein complexes ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 47
    Publication Date: 2024-04-11
    Description: Experiments to characterize the effects of moisture content and temperature on the mechanical properties of concrete were conducted. Based on these experiments, a new overall material model capable of predicting the mechanical behaviour of concrete subject to elevated temperatures up to 100 °C was developed. The material model estimates the time, temperature and moisture dependency of the compressive and tensile strength, creep and shrinkage of concrete.
    Keywords: TA1-2040 ; concrete ; Temperatur ; Beton ; Schwinden ; Temperature ; strength ; Kriechen ; creep ; Festigkeit ; shrinkage ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 48
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Smart sensors are technologies designed to facilitate the monitoring operations. For instance, power consumption can be minimized through on-board processing and smart interrogation algorithms, and state detection enhanced through collaboration between sensor nodes. Applied to structural health monitoring, smart sensors are key enablers of sparse and dense sensor networks capable of monitoring full-scale structures and components. They are also critical in empowering operators with decision making capabilities. The objective of this Special Issue is to generate discussions on the latest advances in research on smart sensing technologies for structural health monitoring applications, with a focus on decision-enabling systems. This Special Issue covers a wide range of related topics such as innovative sensors and sensing technologies for crack, displacement, and sudden event monitoring, sensor optimization, and novel sensor data processing algorithms for damage and defect detection, operational modal analysis, and system identification of a wide variety of structures (bridges, transmission line towers, high-speed trains, masonry light houses, etc.).
    Keywords: TA1-2040 ; T1-995 ; NSGA-II ; wind force ; wavelet packet decomposition ; structural health monitoring ; amplitude spectrum ; environmental noise ; patch antenna ; damage identification ; event-triggered sensing ; Particle Swarm Optimization (PSO) algorithm ; high-speed train ; low-velocity impacts ; concrete structures ; sensors distribution optimization ; acceleration ; digital sampling moiré ; crack ; displacement sensor ; length effect ; FBG sensor array ; SHM ; space window ; Bayesian blind source separation ; feature selection ; stress detection ; wheel minor defect ; strain ; uniaxial stress measurement ; turbine ; impact identification ; helical antenna ; energy analysis of wavelet band ; strain wave ; time window ; structural steel members ; steel frame ; acoustoelastic effect ; demand-based nodes ; online wayside detection ; sensor ; bridge ; sensitivity ; acoustic emission ; bending stiffness ; wireless smart sensors ; distributed dense sensor network ; mapping construction ; data fusion ; fuzzy classification ; shear-wave birefringence ; normal mode ; piezoelectric wafer active sensors ; resonant frequency ; electromagnetic oscillation ; settlement ; sensor optimization ; modal frequencies ; perturbation theory ; feature extraction ; Virtual Distortion Method (VDM) ; reflective optical sensor ; fibre bundle ; smartphones ; crack identification ; active sensing ; test vehicle ; calibration ; stretching method ; model updating ; rotary ultrasonic array ; 2D crack growth ; data processing ; damage detection ; impactor stiffness ; tip clearance ; transmission tower ; phase spectrum ; concrete crack ; structural impact monitoring ; shaking table tests ; optical crack growth sensor ; steel strand ; passive sensing ; sudden event monitoring ; aero engine ; principal component analysis ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 49
    Publication Date: 2024-04-05
    Description: Genome-wide association studies (GWAS) for complex disorders with large case-control populations have been performed on hundreds of traits in more than 1200 published studies (http://www.genome.gov/gwastudies/) but the variants detected by GWAS account for little of the heritability of these traits, leading to an increasing interest in using family based designs. While GWAS studies are designed to find common variants with low to moderate attributable risks, family based studies are expected to find rare variants with high attributable risk. Because family-based designs can better control both genetic and environmental background, this study design is robust to heterogeneity and population stratification. Moreover, in family-based analysis, the background genetic variation can be modeled to control the residual variance which could increase the power to identify disease associated rare variants. Analysis of families can also help us gain knowledge about disease transmission and inheritance patterns. Although a family-based design has the advantage of being robust to false positives, novel and powerful methods to analyze families in genetic epidemiology continue to be needed, especially for the interaction between genetic and environmental factors associated with disease. Moreover, with the rapid development of sequencing technology, advances in approaches to the design and analysis of sequencing data in families are also greatly needed. The 11 articles in this book all introduce new methodology and, using family data, substantial new findings are presented in the areas of infectious diseases, diabetes, eye traits, autism spectrum disorder and prostate cancer.
    Keywords: QH426-470 ; Q1-390 ; Regional heritability ; prostate cancer ; infectious diseases ; MCMC ; combining studies screening ; conditional-logistic linkage ; Informatics ; autism ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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  • 50
    Publication Date: 2022-01-31
    Description: This eBook presents illustrative examples of genetic chaperonopathies affecting primarily nerves and muscles and discusses molecular mechanisms and treatment targeting chaperones, i.e., chaperonotherapy.
    Keywords: Q1-390 ; small-Hsp ; Hsp60/CCT/BBS ; Indirect/Secondary Chaperonopathies ; Genetic Chaperonopathies ; Hsp40/DnaJ ; chaperonotherapy
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  • 51
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Mobile robotics is a challenging field with great potential. It covers disciplines including electrical engineering, mechanical engineering, computer science, cognitive science, and social science. It is essential to the design of automated robots, in combination with artificial intelligence, vision, and sensor technologies. Mobile robots are widely used for surveillance, guidance, transportation and entertainment tasks, as well as medical applications. This Special Issue intends to concentrate on recent developments concerning mobile robots and the research surrounding them to enhance studies on the fundamental problems observed in the robots. Various multidisciplinary approaches and integrative contributions including navigation, learning and adaptation, networked system, biologically inspired robots and cognitive methods are welcome contributions to this Special Issue, both from a research and an application perspective.
    Keywords: TA1-2040 ; T1-995 ; similarity measure ; swarm-robotics ; drag-based system ; PID algorithm ; human–robot interaction ; behaviour dynamics ; state constraints ; fair optimisation ; micro mobile robot ; robot ; actuators ; high-gain observer ; turning model LIP ; space robot ; manipulation action sequences ; subgoal graphs ; remotely operated vehicle ; constrained motion ; joint limit avoidance ; curvilinear obstacle ; rehabilitation system ; stability criterion ; system design ; quad-tilt rotor ; iterative learning ; spiral curve ; cable detection ; SEA ; douglas–peuker polygonal approximation ; predictable trajectory planning ; ATEX ; obstacle avoidance system ; kinematic singularity ; collision avoidance ; biologically-inspired ; jumping robot ; differential wheeled robot ; design and modeling ; control efficacy ; robotics ; extremum-seeking ; object-oriented ; non-holonomic mobile robot ; magneto-rheological fluids ; rendezvous consensus ; altitude controller ; master-slave ; switching control ; deep reinforcement learning ; mechanism ; expansion logic strategy ; negative buoyancy ; action generation ; radial basis function neural networks ; unmanned aerial vehicles ; extend procedure ; glass façade cleaning robot ; convolutional neural network ; climbing robot ; micro air vehicle ; car-like kinematics ; variable speed ; machine learning ; dynamical model ; transportation ; geodesic ; unmanned surface vessel ; medical devices ; stopper ; extended state observer (ESO) ; high efficiency ; object mapping ; multi-objective optimization ; hybrid robot ; robot learning ; auto-tuning ; cable disturbance modeling ; manipulation planning ; pesticide application ; high-speed target ; sparse pose adjustment (SPA) ; service robot ; lumped parameter method ; Geometric Algebra ; dynamic coupling analysis ; Thau observer ; tri-tilt-rotor ; industrial robotic manipulator ; hardware-in-the-loop simulation ; robotic drilling ; muscle activities ; small size ; chameleon ; continuous hopping ; wall climbing robot ; hover mode ; 3D-SLAM ; curvature constraints ; PSO ; drilling end-effector ; Rodrigues parameters ; gait adaptation ; static environments ; position/force cooperative control ; snake-like robot ; shape-fitting ; powered exoskeleton ; input saturation ; kinematic identification ; methane ; human–machine interactive navigation ; q-learning ; path following ; hopping robot ; mobile manipulation ; high step-up ratio ; actuatorless ; monocular vision ; stability analysis ; compact driving unit ; snake robot ; non-holonomic robot ; curvature constraint ; phase-shifting ; dialytic elimination ; gesture recognition ; snake robots ; series elastic actuator ; flapping ; servo valve ; motion camouflage control ; biomimetic robot ; minimally invasive surgery robot ; centralized architecture ; trajectory planning ; computing time ; adaptive control law ; kinematics ; facial and gender recognition ; single actuator ; victim-detection ; shape memory alloys ; undiscovered sensor values ; discomfort ; Differential Evolution ; numerical evaluation ; quadruped robot ; coverage path planning ; localization ; MPC ; n/a ; fault diagnosis ; neural networks ; disturbance-rejection control ; sample gathering problem ; cart ; bio-inspired robot ; opposite angle-based exact cell decomposition ; optimization ; safety ; goal exchange ; hierarchical planning ; ocean current ; robot motion ; nonlinear differentiator ; mapping ; finite-time currents observer ; Newton iteration ; inverse kinematics ; deposition uniformity ; spatial pyramid pooling ; hierarchical path planning ; end effector ; head-raising ; fault recovery ; LOS ; path tracking ; non-inertial reference frame ; step climbing ; obstacle avoidance ; sliding mode control ; symmetrical adaptive variable impedance ; lane change ; quadcopter UAV ; singularity analysis ; biped mechanism ; fault-tolerant control ; dynamic neural networks ; mobile robots ; data association ; UAV ; enemy avoidance ; reinforcement learning ; grip optimization ; safety recovery mechanism ; exoskeleton ; dynamic environment ; uncertain environments ; hybrid bionic robot ; potential field ; robot navigation ; cleaning robot ; unmanned aerial vehicle ; non-singular fast-terminal sliding-mode control ; contact planning ; Lyapunov-like function ; piezoelectric actuator ; transition mode ; non-prehensile manipulation ; multiple mobile robots ; Tetris-inspired ; real-time action recognition ; integral line-of-sight ; topological map ; alpine ski ; target tracking ; closed-loop detection ; working efficiency ; mathematical modeling ; curve fitting ; force control ; biped robots ; NSGA-II ; mobile robot ; load carriage ; prescription map translation ; artificial fish swarm algorithm ; Q-networks ; self-reconfigurable robot ; G3-continuity ; autonomous vehicle ; loop closure detection ; excellent driver model ; robots ; graph representation ; regional growth ; target assignment ; evolutionary operators ; intelligent mobile robot ; motion sensor ; exploration ; droplets penetrability ; dynamic uncertainty ; simultaneous localization and mapping (SLAM) ; area decomposition ; multi-criteria decision making ; 4WS4WD vehicle ; biped climbing robots ; skiing robot ; ROS ; decision making ; smart materials ; centrifugal force ; missile control system ; formation of robots ; electro-rheological fluids ; pneumatics ; variable spray ; inertial measurement unit (IMU) ; Robot Operating System ; trajectory interpolation ; formation control ; immersion and invariance ; dragonfly ; parallel navigation ; harmonic potential field ; pallet transportation ; mobile robot navigation ; negative-buoyancy ; grip planning ; manipulator ; position control ; external disturbance ; legged robot ; passive skiing turn ; autonomous underwater vehicle (AUV) ; gait cycle ; path planning ; sliding mode observer ; dynamic gait ; self-learning ; polyomino tiling theory ; coalmine ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 52
    Publication Date: 2024-04-05
    Description: Virus-caused asthma, we now call a phenotype of asthma. Regardless of the significance and popularity of this disease, the etiology of the virus-induced asthma have not well understood. In addition, a few effective vaccines have been applied to prevent respiratory virus infection. To solve the issues, it is essential to clarify and delineate both aspects of the virus and host defense systems including acute/chronic inflammation and airway tissue remodeling. To deeply review and discuss pathophysiology and epidemiology of virus-induced asthma, this topics includes new findings of the host immunity, pathology, epidemiology, and virology of asthma/chronic obstructive pulmonary disease (COPD). We believe that these works are well summarized and informative to glimpse the field of virus- associated asthma and COPD, and may help understanding the basic and clinical aspects of the diseases.
    Keywords: QR1-502 ; QK1-989 ; Q1-390 ; virus-induced asthma ; Pathology ; respiratory virus ; human immunity ; Epidemiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
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  • 53
    Publication Date: 2024-04-11
    Description: The subject of this PhD-thesis is the transferability of Facility Management (FM) by using the example of hospitals in Germany and Iran. The intention is to determine the status and significance of facility management in the project countries, to analyse similarities, semblances and differences in order to develop a system transferability model.
    Keywords: TA1-2040 ; health system ; facility management ; system transferability ; hospital ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 54
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: This book brings together recent research related to urban resilience, in particular, taking into account climate change impacts and hydrological hazards. Due to the complexity of our cities, which are vulnerable and continuously evolving systems, urban resilience should be considered as a transversal and multi-sectorial issue, affecting different urban services, several hazards, and all the steps of the risk management cycle. Within this context, the different pieces of research that form this book deal with the topics of multi-risk and urban resilience assessment, analysis of cascading effects, and the proposal and prioritization of adaptation measures and strategies to cope with climate-related hazards through multi-criteria analysis.
    Keywords: RESCCUE project ; Electrical distribution network ; Flooding ; Risk Assessment ; city resiliency ; GIS model ; drought ; water scarcity ; water availability ; climate change ; hydrological modeling ; resilience ; flooding ; hazard mapping ; risk identification ; sustainability ; urban resilience ; traffic modelling ; resilience assessment ; urban services ; cities ; Ecosystem Services (ES) ; Nature-Based Solutions (NBS) ; Resilience Assessment Framework (RAF) ; stakeholders’ validation ; stormwater management and control ; depth‒damage curves ; urban floods ; properties ; claims ; flood expert surveyor ; fluvial ; pluvial ; tidal ; sewer ; flood ; risk ; modelling ; cascading effects ; urban flood ; water quality ; cost-benefit analysis ; combined sewer overflows ; climate change adaptation ; climate risk ; socio-economic assessment ; flood risk assessment ; 1D/2D hydrodynamic model ; Metro system ; subway ; urban mobility ; pluvial floods ; 1D/2D coupled models ; impact assessment ; adaptation strategies ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 55
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This Special Issue gathers research from different branches of science and engineering disciplines working on experiments and modelling of nanocomposites into one volume. The Guest Editor welcomes papers dedicated to experimental, computational, and theoretical aspects dealing with many important state-of-the-art technologies and methodologies regarding the synthesis, fabrication, characterization, properties, design, and applications, and both finite element analysis and molecular dynamic simulations, of nanocomposite materials and structures. Full papers covering novel topics, extending the frontiers of the science and technology of nanoreinforced composites are encouraged. Reviews covering topics of major interest will be also considered.
    Keywords: TA1-2040 ; T1-995 ; ab initio ; critical yield strength ; carbon nanotube ; impact buckling ; elasticity ; molecular dynamics simulation ; magnetism ; coarse-grained model ; 3D fiber-metal laminates ; mechanical property ; interface ; nanocomposites ; interface force fields ; YN ; graphene/Fe composite ; cohesive element ; stability ; ScN ; delamination propagation ; interfaces ; graphene nanoplatelets ; nanoindentation ; pressure ; molecular dynamics ; piezoelectric property ; temperature effect ; Fe-Al ; hardness ; equivalent fiber ; disorder ; Fe3Al ; elastic modulus ; delamination buckling ; CNT agglomeration ; CNTs/epoxy nanocomposites ; boron nitride honeycomb ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 56
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The ongoing deployment of 5G networks is a key enabler for realizing upcoming services at scale, including the massive deployment of the Internet of Things, providing communications to support autonomous vehicles, and supporting the realization of smart cities. However, as the limitations of existing approaches become apparent, the need for next-generation technologies is growing, in terms of improving spectral efficiency, increasing network data rates and densification, supporting local/wide area wireless coordination, and more. In this Special Issue, we present some technologies to meet these demanding requirements and facilitate coordinating wireless networks to support future Beyond 5G networks.
    Keywords: 5G fiber optic networks ; data-driven service assurance ; next generation networks ; predictive analytics ; live-video delivery ; 5G networks ; virtualized content delivery networks ; network function virtualization ; service function chain deployment ; deep reinforcement learning ; MAC classification ; vehicular networks ; VANETs ; distributed MAC ; centralized MAC ; multi-channel MAC ; single-channel MAC ; spectrum allocation ; private 5G ; mmWave RAN ; modulation and coding schemes ; spectral efficiency ; self-organization ; self-optimization ; self-healing ; SON applications and architecture ; SON design and dimensioning ; machine learning (ML) and artificial intelligence (AI) for SON ; massive Machine-Type Communication (mMTC) ; IoT ; URLLC ; backhauling ; SON for 3G/4G ; 5G and B5G networks ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNB Energy industries and utilities
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  • 57
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: This book is a collection of Special Issue articles with a multidisciplinary character, linking biology, medicine, and synthetic organic chemistry. The synthesis and full characterization of about 180 novel organic species, both of natural and synthetic origin, often designed with the support of in-silico studies, are set out in the book. In several articles, molecular hybridization approaches have been used as a successful multi-target strategy for the design and development of novel antitumor agents. Rigorous and careful biochemical studies ranging from in-vitro experiments on a plethora of human-cancer derived cell lines to in-vivo and ex-vivo studies allowed the authors to identify the molecular targets and gain useful information on structure–activity relationships (SAR). For this reason, this collection should interest many readers from different scientific fields.
    Keywords: thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 58
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    Frontiers Media SA
    Publication Date: 2024-04-05
    Description: Transfer cells are anatomically specialized cells optimized to support high levels of nutrient transport in plants. These cells trans-differentiate from existing cell types by developing extensive and localized wall ingrowth labyrinths to amplify plasma membrane surface area which in turn supports high densities of membrane transporters. Unsurprisingly, therefore, transfer cells are found at key anatomical sites for nutrient acquisition, distribution and exchange. Transfer cells are involved in delivery of nutrients between generations and in the development of reproductive organs and also facilitate the exchange of nutrients that characterize symbiotic associations. Transfer cells occur across all taxonomic groups in higher plants and also in algae and fungi. Deposition of wall ingrowth-like structures are also seen in “syncytia” and “giant cells” which function as feeding sites for cyst and root-knot nematodes, respectively, following their infection of roots. Consequently, the formation of highly localized wall ingrowth structures in diverse cell types appears to be an ancient anatomical adaption to facilitate enhanced rates of apoplasmic transport of nutrients in plants. In some systems a role for transfer cells in the formation of an anti-pathogen protective barrier at these symplastic discontinuities has been inferred. Remarkably, the extent of cell wall ingrowth development at a particular site can show high plasticity, suggesting that transfer cell differentiation might be a dynamic process adapted to the transport requirements of each physiological condition. Recent studies exploiting different experimental systems to investigate transfer cell biology have identified signaling pathways inducing transfer cell development and genes/gene networks that define transfer cell identity and/or are involved in building the wall ingrowth labyrinths themselves. Further studies have defined the structure and composition of wall ingrowths in different systems, leading in many instances to the conclusion that this process may involve previously uncharacterized mechanisms for localized wall deposition in plants. Since transfer cells play important roles in plant development and productivity, the latter being relevant to crop yield, especially so in major agricultural species such as wheat, barley, soybean and maize, understanding the molecular and cellular events leading to wall ingrowth deposition holds exciting promise to develop new strategies to improve plant performance, a key imperative in addressing global food security. This Research Topic presents a timely and comprehensive treatise on transfer cell biology to help define critical questions for future research and thereby generating a deeper understanding of these fascinating and important cells in plant biology.
    Keywords: QK1-989 ; Q1-390 ; Wall ingrowth ; Arabidopsis thaliana ; synctial cells ; Zea mays ; transfer cells ; endosperm transfer cells ; Giant Cells ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
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  • 59
    Publication Date: 2024-04-05
    Description: Research during the past decade highlights the strong link between appetitive feeding behavior, reward and motivation. Interestingly, stress levels can affect feeding behavior by manipulating hypothalamic circuits and brain dopaminergic reward pathways. Indeed, animals and people will increase or decrease their feeding responses when stressed. In many cases acute stress leads to a decrease in food intake, yet chronic social stressors are associated to increases in caloric intake and adiposity. Interestingly, mood disorders and the treatments used to manage these disorders are also associated with changes in appetite and body weight. These data suggest a strong interaction between the systems that regulate feeding and metabolism and those that regulate mood. This Research Topic aims to illustrate how hormonal mechanisms regulate the nexus between feeding behavior and stress. It focuses on the hormonal regulation of hypothalamic circuits and/or brain dopaminergic systems, as the potential sites controlling the converging pathways between feeding behavior and stress.
    Keywords: RC321-571 ; Q1-390 ; stress ; Obesity ; Dopamine ; Ghrelin ; Leptin ; Seasonal regulation ; feeding ; HPA axis ; Hypothalamus ; circadian rhythms ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 60
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: This Special Issue contains one review and five original articles, all of which address cutting-edge research in the field of water and environmental virology. The review article by Gerba and Betancourt summarizes the current status and future needs for the development of virus detection methods in water reuse systems, especially focusing on methods to assess the infectivity of enteric viruses. Original papers cover a variety of research topics, such as an environmental monitoring survey of group A rotaviruses in sewage and oysters in Japan, the occurrence and genetic diversity of noroviruses and rotaviruses in a wastewater reclamation system in China, the detection of viruses and their indicators in tanker water and its sources in Nepal, integrated culture next-generation sequencing to identify the diversity of F-specific RNA coliphages in wastewater, and the development of a portable collection and detection method for viruses from ambient air and its application to a wastewater treatment plant.
    Keywords: Q1-390 ; reuse ; aerosols ; viral indicator ; wastewater treatment ; microbial contamination ; index virus ; real-time PCR ; tanker water ; virus ; wastewater reclamation ; pathogenic virus ; infectivity ; chlorination ; molecular methods ; wastewater ; next-generation sequencing ; fecal source tracking ; oyster ; fecal-source marker ; viral contamination ; cell culture ; pathogenic microorganisms ; rotavirus ; ultraviolet disinfection ; F-specific RNA bacteriophage strain ; sewage ; waterborne gastroenteritis viruses ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 61
    Publication Date: 2024-04-05
    Description: euromodulation is among the fastest-growing areas of medicine, involving many diverse specialties and affecting hundreds of thousands of patients with numerous disorders worldwide. It can briefly be described as the science of how electrical, chemical, and mechanical interventions can modulate the nervous system function. A prominent example of neuromodulation is deep brain stimulation (DBS), an intervention that reflects a fundamental shift in the understanding of neurological and psychiatric diseases: namely as resulting from a dysfunctional activity pattern in a defined neuronal network that can be normalized by targeted stimulation. The application of DBS has grown remarkably and more than 130,000 patients worldwide have obtained a DBS intervention in the past 30 years—most of them for treating movement disorders. This Frontiers Research Topics provides an overview on the current discussion beyond basic research in DBS and other brain stimulation technologies. Researchers from various disciplines, who are working on broader clinical, ethical and social issues related to DBS and related neuromodulation technologies, have contributed to this research topic.
    Keywords: RC321-571 ; Q1-390 ; Informed Consent ; Deep Brain Stimulation ; Depression ; Neurosurgery ; Movement Disorders ; Neuromodulation ; Enhancement ; Neuroethics ; Philosophy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 62
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: This Special Issue explored different topics concerning recent progress in the synthesis and characterization of suitable innovative macromolecular systems, proposed as carriers of specific antimicrobial molecules, to be employed in the biomedical and pharmaceutical fields. Many infectious diseases are induced by omnipresent micro-organisms, including bacteria, viruses, protozoa, fungi, and algae, and, consequently, are very common, accounting for a significant share of the global disease burden. Unfortunately, antimicrobial resistance, adverse effects, and the high cost of antimicrobials are crucial health challenges worldwide. One of the common efforts in addressing this issue lies in improving the existing antimicrobial delivery systems. In this regard, nanoparticles as well as three-dimensional hydrophilic systems represent valuable tools able to ensure excellent performances. Biocompatible polymeric particles, entrapping these bioactive molecules, are capable of releasing them over a desired period of time, thereby decreasing the frequency of their administration. At the same time, these systems are able to protect antimicrobial drugs from degradation, enhancing their bioavailability. This Special Issue serves to highlight and capture the contemporary progress recorded in this field.
    Keywords: film nanocomposite ; essential oil ; supercritical CO2 ; long-term package ; hybrid nanoparticles ; biocompatible polymer ; antimicrobial amphiphiles ; dynamic light scattering ; scanning electron microscopy ; cell viability from counting of colony-forming unities ; antimicrobial activity of nanoparticles ; Escherichia coli ; Staphylococcus aureus ; Candida albicans ; hydrogel ; polyvinyl alcohol ; aliphatic dicarboxylic acids ; sustained release ; linezolid ; equilibrium swelling ratio ; accumulative release ; thermogravimetric analysis ; gram-negative bacteria ; multidrug resistance ; polymer therapeutics ; colistin ; polymyxin B ; nanoliposomes ; MDR-Bacteria ; chitosan ; nanotechnologies ; plant extracts ; agro-food-wastes ; antimicrobial agents ; polymeric nanocarriers ; mixed polymeric micelles ; drug delivery ; antibiotics ; Pluronic F127 ; antimicrobial agent ; polymeric nanomaterial ; self-assembly ; antimicrobial peptide ; silver nanoparticle ; anti-biofilm ; wound healing ; bromelain ; nisin ; bioactivity ; biomedicine ; carrier ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 63
    Publication Date: 2024-03-29
    Description: The integration of multisensory information is an essential mechanism in perception and in controlling actions. Research in multisensory integration is concerned with how the information from the different sensory modalities, such as the senses of vision, hearing, smell, taste, touch, and proprioception, are integrated to a coherent representation of objects. Multisensory integration is central for action control. For instance, when you grasp for a rubber duck, you can see its size and hear the sound it produces. Moreover, identical physical properties of an object can be provided by different senses. You can both see and feel the size of the rubber duck. Even when you grasp for the rubber duck with a tool (e.g. with tongs), the information from the hand, from the effect points of the tool and from the eyes are integrated in a manner to act successfully. Over the recent decade a surge of interest in multisensory integration and action control has been witnessed, especially in connection with the idea that multiple sensory sources are integrated in an optimized way. For this perspective to mature, it will be helpful to delve deeper into the information processing mechanisms and their neural correlates, asking about the range and constraints of this mechanisms, about its localization and involved networks.
    Keywords: BF1-990 ; Q1-390 ; recalibration ; haptic ; Human Information Processing ; Vision ; Perception ; reference frame ; Acoustics ; Tool Use ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 64
    Publication Date: 2024-04-05
    Description: Volume I, entitled “Augmentation of Brain Functions: Brain-Machine Interfaces”, is a collection of articles on neuroprosthetic technologies that utilize brain-machine interfaces (BMIs). BMIs strive to augment the brain by linking neural activity, recorded invasively or noninvasively, to external devices, such as arm prostheses, exoskeletons that enable bipedal walking, means of communication and technologies that augment attention. In addition to many practical applications, BMIs provide useful research tools for basic science. Several articles cover challenges and controversies in this rapidly developing field, such as ways to improve information transfer rate. BMIs can be applied to the awake state of the brain and to the sleep state, as well. BMIs can augment action planning and decision making. Importantly, BMI operations evoke brain plasticity, which can have long-lasting effects. Advanced neural decoding algorithms that utilize optimal feedback controllers are key to the BMI performance. BMI approach can be combined with the other augmentation methods; such systems are called hybrid BMIs. Overall, it appears that BMI will lead to many powerful and practical brain-augmenting technologies in the future.
    Keywords: RC321-571 ; Q1-390 ; microcircuits ; Brain machine interface (BMI) ; nootropics ; tDCStranscranial direct current stimulation ; neural networks ; neuroprosthesis ; TMS ; implants ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 65
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Photovoltaic (PV) and concentrated solar power (CSP) systems for the conversion of solar energy into electricity are technologically robust, scalable, and geographically dispersed, and they possess enormous potential as sustainable energy sources. Systematic planning and design considering various factors and constraints are necessary for the successful deployment of PV and CSP systems. This book on solar power system planning and design includes 14 publications from esteemed research groups worldwide. The research and review papers in this Special Issue fall within the following broad categories: resource assessments, site evaluations, system design, performance assessments, and feasibility studies.
    Keywords: thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 66
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Open data and policy implications coming from data-aware planning entail collection and pre- and postprocessing as operations of primary interest. Before these steps, making data available to people and their decision-makers is a crucial point. Referring to the relationship between data and energy, public administrations, governments, and research bodies are promoting the construction of reliable and robust datasets to pursue policies coherent with the Sustainable Development Goals, as well as to allow citizens to make informed choices. Energy engineers and planners must provide the simplest and most robust tools to collect, process, and analyze data in order to offer solid data-based evidence for future projections in building, district, and regional systems planning. This Special Issue aims at providing the state-of-the-art on open-energy data analytics; its availability in the different contexts, i.e., country peculiarities; and its availability at different scales, i.e., building, district, and regional for data-aware planning and policy-making. For all the aforementioned reasons, we encourage researchers to share their original works on the field of open data and energy analytics. Topics of primary interest include but are not limited to the following: 1. Open data and energy sustainability; 2. Open data science and energy planning; 3. Open science and open governance for sustainable development goals; 4. Key performance indicators of data-aware energy modelling, planning, and policy; 5. Energy, water, and sustainability database for building, district, and regional systems; 6. Best practices and case studies.
    Keywords: data envelopment analysis ; Kohonen self-organizing maps ; factor analysis ; multiple regression ; energy efficiency ; social media ; energy-consuming activities ; energy consumption ; machine learning ; ontology ; energy performance certificate ; heating energy demand ; buildings ; data mining ; classification ; regression ; decision tree ; support vector machine ; random forest ; artificial neural network ; open data ; electrification modelling ; Malawi ; OnSSET ; MESSAGEix ; reproducibility ; collaborative work ; open modelling and data ; data-handling ; integrated assessment modelling ; data pre- and post-processing ; space heating ; domestic hot water ; market assessment ; EU28 ; district heating ; data analytics ; big data ; forecasting ; energy ; polygeneration ; clustering ; kNN ; pattern recognition ; heating ; building stock ; heat map ; spatial analysis ; heat density map ; building performance simulation ; parametric modelling ; energy management ; model calibration ; Passive House ; energy planning ; energy potential mapping ; urban energy atlas ; urban energy transition ; energy data ; data-aware planning ; spatial planning ; open data analytics ; smart cities ; open energy governance ; urban database ; energy mapping ; building dataset ; energy modelling ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 67
    Publication Date: 2024-04-05
    Description: Photosystem II is a 700-kDa membrane-protein super-complex responsible for the light-driven splitting of water in oxygenic photosynthesis. The photosystem is comprised of two 350-kDa complexes each made of 20 different polypeptides and over 80 co-factors. While there have been major advances in understanding the mature structure of this photosystem many key protein factors involved in the assembly of the complex do not appear in the holoenzyme. The mechanism for assembling this super-complex is a very active area of research with newly discovered assembly factors and subcomplexes requiring characterization. Additionally the ability to split water is inseparable from light-induced photodamage that arises from radicals and reactive O2 species generated by Photosystem II chemistry. Consequently, to sustain water splitting, a “self repair” cycle has evolved whereby damaged protein is removed and replaced so as to extend the working life of the complex. Understanding how the biogenesis and repair processes are coordinated is among several important questions that remain to be answered. Other questions include: how and when are the inorganic cofactors inserted during the assembly and repair processes and how are the subcomplexes protected from photodamage during assembly? Evidence has also been obtained for Photosystem II biogenesis centers in cyanobacteria but do these also exist in plants? Do the molecular mechanisms associated with Photosystem II assembly shed fresh light on the assembly of other major energy-transducing complexes such as Photosystem I or the cytochrome b6/f complex or indeed other respiratory complexes? The contributions to this Frontiers in Plant Science Research Topic are likely to reveal new details applicable to the assembly of a range of membrane-protein complexes, including aspects of self-assembly and solar energy conversion that may be applied to artificial photosynthetic systems. In addition, a deeper understanding of Photosystem II assembly — particularly in response to changing environmental conditions — will provide new knowledge underpinning photosynthetic yields which may contribute to improved food production and long-term food security.
    Keywords: QK1-989 ; Q1-390 ; Arabidopsis thaliana ; photoactivation ; photosynthesis ; Chlamydomonas reinhardtii ; cyanobacteria ; biogenesis ; Photosystem II ; photodamage ; Nicotiana tabacum ; Synechocystis sp. PCC 6803 ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
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  • 68
    Publication Date: 2024-04-05
    Description: Big data is revolutionizing our ability to measure and study the human brain. New technology increases the resolution of images that are being study as well as enables researchers to study the brain as it functions. These technological advances are combined with efforts to collect neuroimaging data on large numbers of subjects, in some cases longitudinally. This combination of advances in measurement and scope of studies requires novel development in the statistical analysis. Fast, scalable, robust and accurate models and approaches need to be developed to make headway on these problems. This volume represents a unique collection of researchers providing deep insights on the statistical analysis of big neuroimaging data.
    Keywords: RC321-571 ; Q1-390 ; fMRI ; Neuroscience ; functional connectivity ; EEG ; Classification ; prediction ; big data ; MEG ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 69
    Publication Date: 2024-04-11
    Description: The specialty section Earthquake Engineering is one branch of Frontiers in Built Environment and welcomes critical and in-depth submissions on earthquake ground motions and their effects on buildings and infrastructures. Manuscripts should yield new insights and ultimately contribute to a safer and more reliable design of building structures and infrastructures. The scope includes the characterization of earthquake ground motions (e.g. near-fault, far-fault, short-period, long-period), their underlying properties, their intrinsic relationship with structural responses, and the true behaviors of building structures and infrastructures under risky and uncertain ground motions. More specific topics include recorded ground motions, generated ground motions, response spectra, stochastic modeling of ground motion, critical excitation, geotechnical aspects, soil mechanics, soil liquefaction, soil-structure interactions, pile foundations, earthquake input energy, structural control, passive control, active control, base-isolation, steel structures, reinforced concrete structures, wood structures, building retrofit, structural optimization, uncertainty analysis, robustness analysis, and redundancy analysis. This eBook includes four original research papers, in addition to the Specialty Grand Challenge article, on the critical earthquake response of elastic-plastic structures under near-fault or long-duration ground motions which were published in the specialty section Earthquake Engineering. In the early stage of dynamic nonlinear response analysis of structures around 1960s, a simple hysteretic structural model and a simple sinusoidal earthquake ground motion input were dealt with together with random inputs. The steady-state response was tackled by an equivalent linearization method developed by Caughey, Iwan and others. In fact, the resonance plays a key role in the earthquake-resistant design and it has a strong effect even in case of near-fault ground motions. In order to draw the steady-state response curve and investigate the resonant property, two kinds of repetition have to be introduced. One is a cycle, for one forced input frequency, of the initial guess of the steady-state response amplitude, the construction of the equivalent linear model, the analysis of the steady-state response amplitude using the equivalent linear model and the update of the equivalent linear model based on the computed steady-state response amplitude. The other is the sweeping over a range of forced input frequencies. This process is quite tedious. Four original research papers included in this eBook propose a new approach to overcome this difficulty. Kojima and Takewaki demonstrated that the elastic-plastic response as continuation of free-vibrations under impulse input can be derived in a closed form by a sophisticated energy approach without solving directly the equations of motion as differential equations. While, as pointed out above, the approach based on the equivalent linearization method requires the repetition of application of the linearized equations, the method by Kojima and Takewaki does not need any repetition. The double impulse, triple impulse and multiple impulses enable us to describe directly the critical timing of impulses (resonant frequency) which is not easy for the sinusoidal and other inputs without a repetitive procedure. It is important to note that, while most of the previous methods employ the equivalent linearization of the structural model with the input unchanged, the method treated in this eBook transforms the input into a series of impulses with the structural model unchanged. This characteristic guarantees high accuracy and reliability even in the large plastic deformation range. The approach presented in this eBook is an epoch-making accomplishment to open the door for simpler and deeper understanding of structural reliability of built environments in the elastic-plastic range.
    Keywords: TA1-2040 ; fling-step input ; Critical response ; Long-duration ground motion ; double impulse ; forward-directivity input ; triple impulse ; robustness ; Near-fault ground motion ; Ground motion ; Ductility factor ; uncertainty ; resonance ; Structural parameter ; Earthquake Response ; Elastic-plastic response ; Interval analysis ; Multiple impulse ; Earthquake input energy ; redundancy ; Upper bound of input energy ; earthquake engineering ; critical excitation method ; Energy transfer function ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 70
    Publication Date: 2024-03-29
    Description: A conversation between two people can only take place if the words intended by each speaker are successfully recognized. Spoken word recognition is at the heart of language comprehension. This automatic and smooth process remains a challenge for models of spoken word recognition. Both the process of mapping the speech signal onto stored representations for words, and the format of the representation themselves are subject to debate. So far, existing research on the nature of spoken word representations has focused mainly on native speakers. The picture becomes even more complex when looking at spoken word recognition in a second language. Given that most of the world’s speakers know and use more than one language, it is crucial to reach a more precise understanding of how bilingual and multilingual individuals encode spoken words in the mental lexicon, and why spoken word recognition is more difficult in a second language than in the native language. Current models of native spoken word recognition operate under two assumptions: (i) that listeners’ perception of the incoming speech signal is optimal; and (ii) that listeners’ lexical representations are accurate. As a result, lexical representations are easily activated, and intended words are successfully recognized. However, these assumptions are compromised when applied to a later-learned second language. For a variety of reasons (e.g., phonetic/phonological, orthographic), second language users may not perceive the speech signal optimally, and they may still be refining the motor routines needed for articulation. Accordingly, their lexical representations may differ from those of native speakers, which may in turn inhibit their selection of the intended word forms. Second language users also have to solve a larger selection challenge—having words in more than one language to choose from. Thus, for second language users, the links between perception, lexical representations, orthography, and production are all but clear. Even for simultaneous bilinguals, important questions remain about the specificity and interdependence of their lexical representations and the factors influencing cross-language word activation. This Frontiers Research Topic seeks to further our understanding of the factors that determine how multilinguals recognize and encode spoken words in the mental lexicon, with a focus on the mapping between the input and lexical representations, and on the quality of lexical representations.
    Keywords: BF1-990 ; Q1-390 ; Phonological knowledge ; Second-language speech ; bilingual and bidialectal lexicon ; spoken word recognition ; lexical access ; orthographic knowledge ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 71
    Publication Date: 2024-03-31
    Description: This forum of comprehensive reviews and research studies on distinct aspects of the pathophysiology of BAV aortopathy provides both the state of the art in the knowledge on this complex disease and novel insights into its causes and consequences. The present collection of focused papers also envisions and proposes new therapeutic strategies, novel biomarkers and original risk stratification criteria, for the improvement of patient management.
    Keywords: QP1-981 ; Q1-390 ; smooth muscle cells ; microRNAs ; aortic root ; endothelial cells ; aortic surgery ; bicuspid aortic valve ; 4DFlow analysis ; aortopathy ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 72
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Catalysis, in the industrial production of chemicals, fuels, and materials, accounts for more than half of gross material production worldwide. Heterogeneous catalysis enables fast and selective chemical transformations, resulting in superior product yield and facilitating catalyst separation and recovery. The synthesis of novel catalysts has emerged as a hot topic for process and product development with numerous research publications and patents. Hence, development of efficient catalysts and their applications is important for sustainable energy production and use, green chemicals production and use, and economic growth. This Special Issue discusses recent developments related to catalysis for the production of sustainable fuels and chemicals and traverses many new frontiers of catalysis including synthesis, characterization, catalytic performances, reaction kinetics and modelling, as well as applications of catalysts for the production of biofuels, synthesis gas, and other green products. This covers the current state-of-the-art catalysis research applied to bioenergy, organic transformation, carbon–carbon and carbon–heteroatoms, reforming, hydrogenation, hydrodesulfurization, hydrodenitrogenation, hydrodemetalization, Fischer–Tropsch synthesis, to name a few. This book highlights new avenues in catalysis including catalyst preparation methods, analytical tools for catalyst characterization, and techno-economic assessment to enhance a chemical or biological transformation process using catalysts for a betterment of industry, academia and society.
    Keywords: HDO ; sulfide catalyst ; NiMo/Al2O3 ; phospholipid ; fatty acid ; choline ; oxidative desulfurization ; oxidative denitrogenation ; hydrotreating ; XPS ; activated carbon ; tert-butyl hydroperoxide ; biofuel ; biodiesel ; hydrocarbon ; waste ; glycerol hydrogenolysis ; in situ hydrogen ; methanol steam reforming ; Ni/Cu/ZnO/Al2O3 catalysts ; chilean natural zeolite ; Brønsted acid sites ; bio-oil upgrade ; catalytic pyrolysis ; nitrogen-doping ; iron nitrides ; light olefins ; CO hydrogenation ; KMnO4 pretreatment ; dry reforming methane (DRM) ; methane ; carbon dioxide ; microwave ; conversion ; catalyst ; selectivity ; thermal integration ; catalyst support ; CoMo sulfided catalyst ; deoxygenation ; cracking and polymerization ; hydrogenation and dehydrogenation ; waste cooking oil ; artificial neural network ; kinetic modeling ; cobalt-praseodymium (III) oxide ; CO-rich hydrogen ; methane dry reforming ; hydrodeoxygenation ; Ni/KIT-6 ; ethyl acetate ; CO2 activation ; methanol synthesis ; atomic layer deposition ; copper nanoparticles ; zinc oxide atomic layer ; hydroprocessing ; FeCu catalysts ; jet fuel ; oleic acid ; catalytic conversion ; catalyst acidity and basicity ; product distribution ; reaction pathways ; molybdenum phosphide ; methyl palmitate ; isomerization ; carboxylic acids upgrading ; ketonization ; deuterated acetic acid ; acetone D-isotopomers distribution ; H/D exchange ; inverse deuterium kinetic isotope effect ; kinetic parameters ; activation energy ; catalytic pyrolysis of biomass ; bio-oil ; sustainable fuels and chemicals ; hydrogenolysis ; desulfurization and denitrogenation ; CO2 utilization ; pyrolysis and cracking ; syngas and hydrogen ; biomass and bio-oil ; catalysis ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 73
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: The diversity of wood and non-wood forest products is enormous and reflected in their anatomical, physical and chemical properties as well as their potential applications. Special attention should be given to lesser-known species and even to invasive species, which may be profitable when properly managed, thereby decreasing the overexploitation of threatened species. Besides the market importance of stem wood, other tree components and non-wood forest products, often regarded simply as forest residual materials, are valuable forest resources with various potential applications that can strengthen the circular economy. Assessing the characteristics of these diverse materials, such as their structure and anatomy as well as their physical and chemical properties, is fundamental for evaluating their potential and increasing high-quality end-uses. This knowledge will also contribute to sustainable forest management with enhanced forest diversity and species conservation in addition to the reinforcement of certification and environmental policies.
    Keywords: Calamus zollingeri ; Calamus ornatus ; dynamic vapor sorption ; basic density ; volumetric swelling ; white rot ; mold ; Quercus suber L. ; seasonal variation ; cuticular waxes ; leaves ; new species ; morphology ; wood ; properties ; chemical composition ; spectroscopy ; chemometrics ; unconventional species ; Quercus suber ; cork borer ; cork ; phenolics ; tropical species ; wood anatomy ; wood density ; wood color ; multivariate analysis ; species diversity ; dark-brown zone ; lenticular filling tissue ; quantitative anatomical characteristics ; Quercus variabilis ; reproduction cork ; scanning electron microscopy ; sclereid ; virgin cork ; Cytisus scoparius ; liquefied ; optimization ; eco-valorization ; agro-industrial residues ; Asparagaceae ; lignocellulose ; crystalline cellulose ; syringyl/guaiacyl ; anatomy ; Tilia amurensis Rupr. ; Tilia mandshurica Rupr. & Maxim. ; branch ; wood properties ; papermaking material ; tropical timber ; color parameters ; mid-infrared spectroscopy ; FTIR ratios ; environmental factors ; West African Sahel ; Cupressus funebris Endl. wood ; wood knots ; physical properties ; wood color properties ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNA Agribusiness and primary industries::KNAL Forestry industry
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  • 74
    Publication Date: 2024-03-29
    Description: This research topic stems from the "Interdisciplinary Approaches to Multilingualism" conference, which was hosted by the Language Research Centre at the University of Calgary. It was the first conference of its kind, which brought together the work of researchers, educators, and policy makers in the areas of first and second language acquisition from psycholinguistic and pedagogical perspectives. The goal was to provide an opportunity for participants to engage with the implications of multilingualism from a range of perspectives, including the effects of being bilingual from infancy to adulthood, the process and benefits of learning multiple languages, and the impact of multilingualism on society.
    Keywords: BF1-990 ; Q1-390 ; Developmental psycholinguistics ; second language literacy development ; Multilingualism ; psycholinguistic research methods ; Second language pedagogy ; bilingualism ; Second Language Acquisition ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 75
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Energy is an important material basis that can promote the development of human society. Despite the increasing use of renewable energy, the overall energy supply is dominated by fossil fuels. For a long period of time, the main consumption proportion of fossil energy will not change. With the perspective of fossil fuels such as coal, oil, natural gas, shale oil, shale gas, and combustible ice, energy exploration, reservoir reconstruction, and intelligent applications in energy exploitation and energy occurrence geology are currently explored from the perspectives of exploration and exploitation technology. This reprint summarizes the intelligent unmanned mining and its development trends and conducts various research studies, including the stratigraphic correlation of sandy conglomerate in the Yellow River Delta Sag of the Bohai Bay basin, the growth and distribution of coal-measured hydrocarbon source rocks in a mixed platform, the physical and mechanical properties of sandstone, mudstone and granite in the geological environment of deep energy reservoirs, the formation mechanism of energy reservoirs and gas reservoirs, the two-phase flow experiment and numerical simulation in energy mining, the evolution law of cracks in the surrounding rock and the reinforcement principle of gradient support, and the comparison of particle pickup by axial flow and swirling flow in horizontal pneumatic conveying.
    Keywords: intelligent mine ; smart mining ; intelligent working face ; intelligent control ; adaptive ; robotic technology ; seismic rock physics ; sandstone and mudstone ; P-wave and S-wave velocity ; pressure ; temperature ; sandy conglomerate ; Huanghekou Sag ; stratigraphic correlation ; calcite U-Pb dating ; detrital zircon ; pressure-controlled pyrolysis ; oil–water separation ; centrifugal force ; two-phase vapor separation ; cyclone separation ; Tarim Basin ; mixed platform ; delta ; coal-measure distribution ; coal-measure logging response ; axial flow ; swirling flow ; pickup behavior ; coefficient of variation ; tight sandstone gas reservoir ; nuclear magnetic resonance ; fracture ; water blocking ; n/a ; rock mechanical properties ; MMTS ; geothermal development ; geothermal reservoir ; different depth of occurrence ; gas storage ; injection production simulation ; effective permeability ; seepage law ; two-dimensional simulation experiment ; fracture evolution law ; fractured seepage zone ; gradient failure support ; hierarchical control mechanism ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 76
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Robotics and control are both research and application domains that have been frequently engineered through the use of interdisciplinary approaches like cybernetics. Cognition is a particular concept of this approach, abstracted from the context of living organisms to that of artificial devices, and is concerned with knowledge acquisition and understanding through thought, experience, and the senses. Cognitive robotics and control refer to knowledge processing as much as knowledge generation from problem understanding, leading to special forms of architectures that enable systems to behave in an autonomous way. The main aim of this book is to highlight emerging applications and address recent breakthroughs in the domain of cognitive robotics and control and related areas. Procedures, algorithms, architectures, and implementations for reasoning, problem solving, or decision making are considered in the domain of robotics and control.
    Keywords: initial trajectory ; trajectory optimization ; Bézier surface ; robotics ; open FPGAs ; robot control ; surgical robotics ; human–machine interaction ; autonomous guidance ; low-cost platform ; FPGA ; S-curve ; motion control ; SoC ; telemanipulation ; haptics ; machine learning ; gesture recognition ; upper limb rehabilitation robot ; particle swam optimization (PSO) ; artificial bee colony (ABC) ; Ziegler Nichols ; Maximum sensitivity ; ontology ; robot task planning ; knowledge base ; knowledge representation ; industrial collaborative robots ; shared robotic tasks ; physical human–robot interaction ; human intention recognition ; time series classification ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 77
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: “Personalised Nutrition” represents any initiative that attempts to provide tailor-made healthy eating advice based on the nutritional needs of each individual, as these are dictated by the individual’s behaviour, phenotype and/or genotype, and their interactions. This Special Issue of Nutrients is dedicated to the development, implementation and assessment of the effectiveness of evidence-based “Personalised Nutrition” strategies. In this regard, a selection of reviews and original research manuscripts will bring together the latest evidence on how lifestyle habits, physiology, nutraceuticals, gut microbiome and genetics can be integrated into nutritional solutions, specific to the needs of each individual, for maintaining health and preventing diseases.
    Keywords: QH301-705.5 ; Q1-390 ; TX341-641 ; n/a ; gene-based ; taste ; postprandial leptin ; children ; personalised ; obesity ; macronutrient composition ; gastrointestinal symptoms ; postprandial adiponectin ; formula diet ; avoidance diet ; weight loss ; weight ; omega-3 fatty acids ; microbiome ; genotype ; nutrition ; direct-to-consumer test ; intervention ; clinical nutrition ; postprandial total ghrelin ; dietary intervention ; microbiota ; low-carbohydrate diet ; insulin ; FADS polymorphism ; adults ; genetics ; diet ; healthcare professionals ; HbA1c ; PROX1 gene ; phenotype ; high-fat meal ; glucose ; personalised nutrition ; irritable bowel syndrome ; dietary recommendation ; postprandial metabolic fingerprinting ; type 2 diabetes mellitus risk ; high-carbohydrate meal ; health ; ultra-high performance liquid chromatography ; food allergy ; normo-carbohydrate meal ; nutrimetabolomics ; type 2 diabetes ; nutrigenetics ; gene–diet interaction ; personalized nutrition ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 78
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-28
    Description: New scientific advances in different areas have allowed the design of more precise strategies for the prevention and treatment of metabolic disorders through nutrition. In this context emerges the term Precision Nutrition, a new approach that takes advantage of scientific knowledge about the interaction of internal and external environmental factors to develop dynamic and precise nutritional recommendations. Therefore, Precision Nutrition includes personalized advice based on genetics and well-documented gene–nutrient–phenotype interactions, as well as other factors such as individual metabolome, transcriptome, and microbiota profile; food behavior; and dietary, physical activity, and life-style habits; and the resulting interactomes. Precision Nutrition should be based at least on three sequential steps: conventional nutritional approaches (considering age, gender, and physiological states); the incorporation of nutritional and health status information (e.g., metabolites, physical and nutritional behavior); and the genetic baggage including multiomics functional integration.
    Keywords: dietary parameters ; carbohydrate intake ; obesity ; single nucleotide polymorphism ; CLOCK gene ; rs3749474 ; sodium intake ; hypertension ; single-nucleotide polymorphism ; personalized nutrition ; dietary vitamin A ; body fat ; UCP ; retinoic acid ; PBMC ; genetic variant ; weight loss ; nutrigenomics ; dietary intervention ; FTO gene ; dietary protein ; dietary carbohydrates ; dietary fat ; macronutrients ; gene-diet interaction ; glucose homeostasis ; glaucoma ; polygenetic-risk scores ; gene-gene interaction ; gene-nutrient interaction ; precision medicine ; childhood ; insulin resistance ; adipokine ; metabolomics ; biomarkers ; ELOVL ; metabolic alterations ; Mexican population ; Single Nucleotide Polymorphisms ; pediatrics ; cardiometabolic risk factors ; precision nutrition ; eating behavior ; nutrigenetics ; microbiota ; metabolic syndrome ; Mediterranean diet ; genetic risk score ; HELENA ; adolescents ; sex ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBC Cultural and media studies::JBCC Cultural studies::JBCC4 Cultural studies: food and society
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  • 79
    Publication Date: 2024-04-05
    Description: In the last decade, sleep spindles have attracted steadily increasing attention. This interest is motivated by the many intriguing relationships between spindles and various diseases (e.g., schizophrenia, Parkinson, Alzheimer, autism, mental retardation), recovery processes (e.g., post brain stroke), and cognitive faculties (e.g., memory consolidation, intelligence, dream recall, sleep preservation). Nonetheless, a methodological wall has impeded the study of sleep spindles. Their investigation rests heavily on our ability to reliably and consistently identify spindle patterns from background EEG activity, a task involving many obstacles, including: a fuzzy definition of spindles, low inter-expert agreement on their scoring, lack of consensus on standard techniques for their automated detection, low reproducibility of observed characteristics and correlates, unavailability of large, standardized, high-quality databases, and inconsistencies in the methods used to evaluate the performance of automated detectors. The primary aims of this research topic were to bring together world-class researchers on a project designed to facilitate exchanges on methodological difficulties encountered in assessing sleep spindles and to promote standardized spindle-related resources. In preparing their contributions, authors were encouraged to use existing – or to propose new – publicly available resources for assessing sleep spindles. To allow fair and accurate comparison of reported results, the authors were also encouraged to validate their tools on a common benchmark. A database containing expert spindle scoring (i.e., the Montreal Archive of Sleep Studies) was made publicly available for that purpose.
    Keywords: RC321-571 ; Q1-390 ; Neural oscillations ; Electroencephalography (EEG) ; Sleep ; Sleep Spindles ; Memory ; IQ ; sigma waves ; automatic detection ; biomarker ; Open access ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 80
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    Unknown
    Frontiers Media SA
    Publication Date: 2024-03-31
    Description: Energy metabolism is central to life and altered energy expenditure (EE) is often cited as a central mechanism responsible for development of the obese phenotype. Resting EE, EE of physical activity, cold induced thermogenesis and thermic effect of feeding add to produce total EE but can also affect each other. It is thus very important that each component be well measured. Measuring energy expenditure by indirect calorimetry is extremely simple in theory but the practice if far more difficult. Taking into account temperature in small sized animals, measuring accurately the effect of activity on EE, correcting EE for body size body composition, age sex etc… add difficulties in producing reliable data. The goal of this Research Topic was to call for the practical experience of main investigators trained to practice calorimetry in order to get their feedback and the way they deal with the various and specific problems of humans and animal calorimetry. The goal is to share the questions/solutions experienced by the contributors to inititate a “guide of the good practices” that can be periodically updated and used by all those who are and will be interested in measuring energy metabolism from the 20g mouse to the human and large farm animals.
    Keywords: QP1-981 ; Q1-390 ; Body Composition ; Thermogenesis ; brown adipose tissue ; Body Size ; Energy Expenditure ; indirect calorimetry ; physical activity ; metabolic Phenotyping ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 81
    Publication Date: 2023-12-20
    Description: Landscapes have long been viewed as ‘multifunctional’, integrating ecological, economic, sociocultural, historical, and aesthetic dimensions. Landscape science and public awareness in Europe have been progressing in leaps and bounds. The challenges involved in landscape-related issues and fields, however, are multiple and refer to landscape stewardship and protection, as well as to the development of comprehensive theoretical and methodological approaches, in tandem with public sensitization and participatory governance and in coordination with appropriate top-down planning and policy instruments. Landscape-scale approaches are fundamental to the understanding of past and present cultural evolution, and are now considered to be an appropriate spatial framework for the analysis of sustainability. Methods and tools of landscape analysis and intervention have also gone a long way since their early development in Europe and the United States. Although significant progress has been made, there remain many issues which are understudied or not investigated at all—at least in a Mediterranean context. This Special Issue addresses the application of landscape theory and practice in the Eastern Mediterranean and mainly, but not exclusively, reports on the outcomes of an international conference held in Jordan, in December 2015, with the title “Landscapes of Eastern Mediterranean: Challenges, Opportunities, Prospects and Accomplishments”. The focus of this Special Issue, landscapes of the Eastern Mediterranean region, thus constitutes a timely area of research interest, not only because these landscapes have so far been understudied, but also as a rich site of strikingly variegated, long-standing multicultural human–environmental interactions. These interactions, resting on and taking shape through millennia of continuity in tradition, have been striving to adapt to technological advances, while currently juggling with manifold and multilayered socioeconomic and climate–environmental crises.
    Keywords: G1-922 ; Q1-390 ; n/a ; landscape archaeology ; Cyprus ; Landscape Character Assessment (LCA) ; Eastern Mediterranean ; Land Description Units ; stakeholders’ analysis ; UK ; local authority ; ancient sanctuaries ; East Med landscape ; Twain-born Border Lord ; Landscape Decision Support System ; mapping ; topography ; Byzantine landscape and garden art ; economy ; LCA ; classification ; churches ; Arabic-speaking ; participatory ; Landscape Risk Assessment Model ; landforms ; GIS ; planning ; typology ; Greek-speaking ; public realm ; landscape changes ; sacred space ; comparative study ; urban environment ; ideology ; political power ; Arabic landscape and garden art ; cultural sustainability ; historical maps ; religion ; rural land ; multi-functional landscapes ; Lebanon ; Mediterranean ; geographical information system ; spatial distributions ; Land Description Unit (LDU) ; political sustainability ; landscape ; landscape character assessment ; governance ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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  • 82
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In recent years, the implementation of sustainable concrete systems has been a topic of great interest in the field of construction engineering worldwide, as a result of the large and rapid increase in carbon emissions and environmental problems resulting from traditional concrete production and industry. For example, the uses of supplementary cementitious materials, geopolymer binder, recycled aggregate and industrial/agricultural wastes in concrete are all approaches to building a sustainable concrete system. However, such materials have inherent flaws due to their variety of sources, and exhibit very different properties compared with traditional concrete. Therefore, they require specific modifications in preprocessing, design, and evaluation before use in concrete. This reprint, entitled “Advances in Sustainable Concrete System”, covers a broad range of advanced concrete research in environmentally friendly concretes, cost-effective admixtures, and waste recycling, specifically including the design methods, mechanical properties, durability, microstructure, various models, hydration mechanisms, and practical applications of solid wastes in concrete systems.
    Keywords: high-strength concrete ; energy evolution ; elastic strain energy ; brittleness evaluation index ; concrete ; humidity ; moisture absorption ; moisture desorption ; numerical simulation ; acoustic emission ; AE rate process theory ; corrosion rate ; damage evolution ; axial load ; precast concrete structure ; lattice girder semi-precast slabs ; bending resistance ; FE modelling ; concrete damage ; GSP ; high strength ; hydration ; strength ; penetrability ; rice husk ash ; sustainable concrete ; artificial neural networks ; multiple linear regression ; eco-friendly concrete ; green concrete ; sustainable development ; artificial intelligence ; data science ; machine learning ; bagasse ash ; mechanical properties ; natural coarse aggregate ; recycled coarse aggregate ; two-stage concrete ; materials design ; recycled concrete ; crumb rubber concrete ; crumb rubber ; NaOH treatment ; lime treatment ; water treatment ; detergent treatment ; compressive strength ; materials ; adhesively-bonded joint ; temperature aging ; residual strength ; mechanical behavior ; failure criterion ; steel slag powder ; compound activator ; mortar strength ; orthogonal experiment ; GM (0, N) model ; ultrafine metakaolin ; silica fume ; durability ; fiber-reinforced concrete ; damage mechanism ; uniaxial tension ; cracked concrete ; crack width ; crack depth ; tortuosity ; sustainability ; concrete composites ; sulfate and acid attacks ; WPFT fibers ; coal gangue ; gradation ; cement content ; unconfined compressive strength ; freeze–thaw cycle ; minimum energy dissipation principle ; three-shear energy yield criterion ; damage variable ; constitutive model ; phosphorus slag ; limestone ; sulphate-corrosion resistance ; volume deformation ; blast furnace ferronickel slag ; alkali-activated material ; dosage of activator ; reactive powder concrete ; beam-column joint ; FE modeling ; crack ; cementitious gravel ; fly ash ; age ; optimal dosage ; bamboo ; sawdust ; pretreatment ; bio-based material ; mechanical property ; self-compacting concrete ; supplementary cementitious materials ; hydration mechanisms ; microstructure ; fresh properties ; synthetic polymer ; high temperature ; bentonite-free drilling fluid ; rheology ; filtration ; FRP reinforced concrete slab ; punching shear strength ; SHAP ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TN Civil engineering, surveying and building::TNK Building construction and materials::TNKX Conservation of buildings and building materials
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  • 83
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This book is a collection of recent publications from researchers all over the globe in the broad area of high-voltage engineering. The presented research papers cover both experimental and simulation studies, with a focus on topics related to insulation monitoring using state-of-the-art sensors and advanced machine learning algorithms. Special attention was given in the Special Issue to partial discharge monitoring as one of the most important techniques in insulation condition assessment. Moreover, this Special Issue contains several articles which focus on different modeling techniques that help researchers to better evaluate the condition of insulation systems. Different power system assets are addressed in this book, including transformers, outdoor insulators, underground cables, and gas-insulated substations.
    Keywords: TA1-2040 ; T1-995 ; artificial neural network ; simulation ; high-frequency ; artificial flashover tests ; wide bandgap power modules ; tracking ; electrical field strength ; fast-rise square wave voltages ; FDTD simulation ; cable joint ; corona discharge ; feature selection ; post insulator ; earthing systems ; wind speed ; surface discharge ; oil/paper insulation ; oil-paper insulation ; high-magnitude currents and impulse polarity ; UFVM ; Tettex 9520 ; electrical tree ; flashover characteristics ; composite insulator ; partial discharge ; numerical modeling ; saline mechanism ; thermal parameters ; space charge density ; seasonal ; ion flow field ; denoising ; DDX 9121b ; temperature ; transformer asset management ; cavity discharge ; space/interface charge ; insulation health index ; heat transfer model ; leakage current ; machine learning ; partial discharges (PD) ; RF signal ; flashover ; high impulse conditions ; grounding electrodes ; generalized finite difference time domain ; curve fitting ; grounding ; plasma discharge ; outdoor insulators ; flashover dynamic model ; wavelet transform ; degradation ; thermal properties ; bipolar charge transport model ; UHF sensor ; cable ; random walk theory ; tracking test setup ; GIL ; pressure ; modelling ; non-uniform pollution between windward and leeward sides ; calibrator ; secondary arc ; polymeric insulation ; optical-UHF integrated detection ; shoreline ; dry band arcing ; photoelectric fusion pattern ; DDX 8003 ; XLPE ; silicone gel ; partial discharge modeling ; electric field analysis ; NSCT ; electrode’s geometry ; gas ; Comsol Multiphysics ; fast-impulses ; laying modes ; ageing ; cable ampacity ; residual resistance formulation ; finite element analysis ; thermal effect ; hydrophobicity ; soil resistivity ; charge simulation method ; short-circuit discharge ; dry band formation ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: In light of the considerable impact of global food supply chains on climate change, more sustainable ways of producing, distributing, and consuming food appear critical for sustainable development. With the aim of contributing to this topic, this Special Issue on sustainable food consumption and food marketing addresses various relevant issues related to food consumption, including innovative and sustainable forms of food production and consumption, animal welfare and meat consumption, price transmission, social media communication, alternative food production, and organic agriculture, among others. As such, this Special Issue sheds light on more sustainable and carbon-friendly food production and consumption systems from various angles. It delivers valuable scientific evidence for the transformation of current carbon-based food supply chains to more eco-friendly, fair, and future-oriented food supply chains.
    Keywords: aquaponics ; Structural Equation Modeling ; consumer behavior ; purchase intention ; willingness to pay ; sustainability ; food market ; veganic ; vegan-organic ; vegan ; stockless ; attitudes ; environmental marketing ; green product ; green consumer ; green purchase decision ; consumer behaviour ; theory of planned behaviour ; sustainable consumption ; Bangladesh ; out-of-home catering ; sustainable nutrition ; variety seeking ; spontaneous choice ; company canteens ; trust ; social media ; small and medium enterprises ; Bresse Gauloise ; choice experiment ; dual-purpose breeds ; faba beans ; Kollbecksmoor ; theory of planned behavior ; Vorwerkhuhn ; White Rock ; green products ; palm oil free ; structural equation modeling ; SEM ; sustainable food consumption ; food waste ; theoretical framework ; food tourism ; community-based tourism ; sustainable development ; community engagement ; rural development ; food heritage ; carbon-friendly food ; emotions ; animal welfare ; cured ham ; discrete choice experiment ; latent construct model ; market instability ; nonlinear empirical dynamics ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 85
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Cognitive building is a pioneering topic envisioning the future of our built environment. The concept of "cognitive" provides a paradigm shift that steps from the static concept of the building as a container of human activities towards the modernist vision of "machine à habiter" of Le Corbusier, where the technological content adds the capability of learning from users' behavior and environmental variables to adapt itself to achieve major goals such as user comfort, energy-saving, flexible functionality, high durability, and good maintainability. The concept is based on digital frameworks and IoT networks towards the concept of a smart city.
    Keywords: explainable post occupancy ; humanoid robot ; lighting simulation software ; BIM ; openBIM ; IFC ; IoT ; sensors ; cognitive buildings ; asset management ; digital twin ; BEM ; simulation modelling ; dynamic simulation ; Building Information Modelling (BIM) ; Internet of Things (IoT) ; facility management ; cyber-physical systems ; Building Management System ; Digital Twin ; Post-Occupancy Evaluations ; cognitive ; digital twins ; building lifecycle management ; artificial intelligence ; decision support ; self-learning ; optimization ; building performance simulation ; lighting simulation ; lighting quality ; visual comfort ; office field study ; evidence-based design ; building information modeling ; HVAC ; fan coil ; Internet of Things ; predictive maintenance ; fault detection ; smart building ; sustainable building ; construction projects ; BIM implementation ; stakeholders ; barriers ; construction product ; servitization ; level of evidence ; level curves ; ground slopes ; embankments ; road and rail design ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 86
    Publication Date: 2024-04-11
    Description: Energy systems worldwide are undergoing major transformation as a consequence of the transition towards the widespread use of clean and sustainable energy sources. Basically, this involves massive changes in technical and organizational levels together with tremendous technological upgrades in different sectors ranging from energy generation and transmission systems down to distribution systems. These actions generate huge science and engineering challenges and demands for expert knowledge in the field to create solutions for a sustainable energy system that is economically, environmentally, and socially viable while meeting high security requirements. This book covers these promising and dynamic areas of research and development, and presents contributions in sustainable energy systems planning, integration, and management. Moreover, the book elaborates on a variety of topics, ranging from design and planning of small- to large-scale energy systems to the operation and control of energy networks in different sectors, namely electricity, heat, ?and transport.
    Keywords: TA1-2040 ; T1-995 ; n/a ; Romanian coastal environment ; neural networks ; intermittent heating ; wind velocities ; time-space network ; optimal chiller loading (OCL) ; renewable energy ; pure electric buses ; mixed-integer non-linear programming problem (MINLP) ; control system ; FANP ; energy consumption ; load regulation ; energy ; smart box ; novel method ; smart logistics system ; multiple uncertainties ; non-intrusive load monitoring ; wind speed forecasting ; solid waste to energy plant ; uncertain cooling demand ; dual robust optimization ; Black Sea ; field test and numerical simulation ; electric power ; sustainable development ; multi-type bus operating organization ; cuckoo search algorithm ; vehicular emissions ; SWAN ; public transport ; product quality model ; MCDM ; TOPSIS ; heat transfer ; solar energy ; forecasting validity ; information gap decision theory (IGDT) ; photovoltaic systems ; configurations of internal wall ; ensemble empirical mode decomposition ; agricultural pruning ; hot summer and cold winter climate zone ; energy and environmental systems ; feature extraction ; information platform ; pruning biomass ; smart grid ; product usability testing ; meteorological variables ; fuzzy logic ; performance evaluation ; rural residential building ; threshold value of daily operation hours ; datacenter ; wave energy ; thermal comfort ; heat storage and release ; resampling ; risk aversion ; environment ; support vector machine ; internal coverings ; numerical models ; gradient descent ; renewable biomass energy ; demand response ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 87
    Publication Date: 2023-12-21
    Description: Aflatoxins are a group of polyketide mycotoxins that are produced mainly by members of the genus Aspergillus. Production of these toxic secondary metabolites is closely related to fungal development (Keller et al., 2005; Jamali et al., 2012). Contamination of food, feed and agricultural commodities by aflatoxins poses enormous economic and serious health concerns because these chemicals are highly carcinogenic and can directly influence the structure of DNA. The resulting genetic defects can lead to fetal misdevelopment and miscarriages; aflatoxins are also known to suppress immune systems (Razzaghi-Abyaneh et al., 2013). In a global context, aflatoxin contamination is a constant concern between the 35N and 35S latitude where developing countries are mainly situated. With expanding boundaries of developing countries, aflatoxin contamination has become a persistent problem to those emerging areas (Shams-Ghahfarokhi et al., 2013). The continuing threat by aflatoxin contamination of food, feed and agricultural commodities to the world population has made aflatoxin research one of the most exciting and rapidly developing study areas of microbial toxins. The present research topic includes six review articles, three mini reviews and four original research articles. Contributors highlight current global health issues arising from aflatoxins and aflatoxigenic fungi and cover important aspects of aflatoxin research including contamination of crops, epidemiology, molecular biology and management strategies. Special attention is given to fungus-plant host interactions, biodiversity and biocontrol, sexual recombination in aflatoxigenic aspergilli, potential biomarkers for aflatoxin exposure in humans and safe storage programs.
    Keywords: R5-920 ; QR1-502 ; Q1-390 ; TX341-641 ; genetic diversity ; Public Health ; Aspergillus flavus ; Genomics ; MicroRNAs ; Fungus host interactions ; biological control ; aflatoxin ; agricultural crops ; bic Book Industry Communication::M Medicine
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The last few decades have seen rapid development in the field of surface engineering and its applications in almost all industrial sectors. Tribological coatings, which are an important aspect of surface engineering, are today applied on machine component surfaces for a diverse range of moving machine components to control (mostly to minimize) friction and wear in order to conserve energy and materials. This reprint book is a compilation of 11 research papers contributed by experts in the field of surface engineering and tribology. These papers have dealt with the synthesis of various types of coatings, characterization and applications under different operating conditions. It is hoped that this reprint book will be of interest, not only to researchers, but also to practicing engineers and technologists in the industry.
    Keywords: Cr-Ti-B-N films ; magnetron sputtering ; microstructure ; friction and wear ; GH4169 alloy ; Ag–Mo co-implantation ; ion-beam-assisted bombardment technology (IBAB) ; wear mechanism ; polymer coating ; graphene ; tribological properties ; elevated temperature ; VCN–Cu films ; mechanical ; friction property ; wear property ; high-entropy alloy (HEA) matrix coating ; plasma spraying ; wear resistance ; microhardness ; bonding strength ; Cu/MoS2 coatings ; Cu-Al/MoS2 coatings ; annealing treatment ; γ2-Cu9Al4 phase ; scratch test ; acoustic emission ; thin films ; silicon carbide ; multilayered AlCrN coating ; Raman spectroscopy ; tribo-corrosion ; sliding wear ; DLC ; MoS2 ; coating ; elastomer ; seals ; TiB2 ; ZrB2 ; coating blade ; anti-wear ; stainless steel coating ; sputtering ; wear ; adhesion ; friction ; structure ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 89
    Publication Date: 2024-04-05
    Description: Helicases are the proteins that bind to double- or single-stranded DNA and/or RNA chains to unwind higher order structures, usually consuming energy from the hydrolysis of ATP molecules. The biological roles of helicases are associated with a variety of DNA and/or RNA metabolisms, including DNA-replication, -repair, -recombination, RNA processing, and transcription. Dysfunctions of helicases cause various diseases, such as xeroderma pigmentosum (XP), premature aging syndrome, cancer and immunodeficiency, in humans. Moreover, recent genetic analyses revealed that mutations in helicase-encoding genes are frequently found in patients of specific diseases. Some helicases regulate cellular senescence by controlling integrity of genomes, and others play a role in neuromuscular functions presumably by modulating processing of mRNAs. However, the molecular mechanisms of how helicases are regulated in order to maintain our health are not yet fully understood. In this research topic, we will focus on the expression and functions of helicases and their encoding genes, reviewing recent research progresses that provide new insights into development of clinical and pharmaceutical treatments targeting helicases.
    Keywords: QH426-470 ; Q1-390 ; DNA Repair ; Aging ; helicases ; Telomere ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
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  • 90
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-12-20
    Description: The practical importance of economic valuation information can hardly be overstated. Coastal and marine resource policy planning and management benefit from complete information on the impact of policy decisions.
    Keywords: Q1-390 ; internet survey ; open access ; contingent valuation method ; coastal management ; tourism ; Thailand ; marine ; wetlands ; harmful algae blooms ; environmental valuation ; quota ; cyanobacteria ; estuarine and coastal ecosystems ; wealth accounting ; seawater quality ; economic analysis ; remote sensing ; ecosystem restoration ; coastal ecosystems ; random utility model ; contingent behavior ; public policy ; habitat–fishery linkages ; Barbados ; coastal ecosystem services valuation ; fishery ; mangroves ; ecosystem services valuation ; coral reefs valuation ; recreational boating ; regulated open access ; non-market value ; economic valuation ; ecosystem services ; coastal ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general
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  • 91
    Publication Date: 2024-03-27
    Description: This reprint focuses on exploring the relationship between urban form, mobility, and social well-being across neighborhoods, cities, and regions. Understanding more about these relationships is helpful in shaping integrated sustainable urban planning and transport development strategies. All reprint chapters primarily contribute to the existing literature on the interdisciplinary field of the impact of urban planning and transport on social well-being and facilitate novel ways of measuring the abstract concept of well-being, particularly in Asian and European countries. We suggested that further research could explore these themes in greater depth by means of both theoretical frameworks and methodological developments in this integrated field.
    Keywords: social well-being ; social equity ; quality of life ; behavioural change and decision making ; urban mobility ; travel behaviour ; sustainable transport development ; urban and transport modelling ; urban form ; urban planning ; sustainable cities ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
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  • 92
    facet.materialart.
    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-05
    Description: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
    Keywords: QH301-705.5 ; Q1-390 ; STRIPAK ; skin cancer ; n/a ; Lats2 ; transcription ; myofibroblast ; epigenetic ; Hippo ; cancer immunity ; TAZ ; Taz ; TAZ (transcriptional co-activator with PDZ-binding motif) ; adaptive immunity ; fibroblasts ; innate immunity ; LATS ; MST (mammalian STE20-like protein kinase) ; phosphorylation ; stem cells ; wound healing ; signal transduction ; angiogenesis ; LATS1/2 ; EMT ; protein-protein interactions ; structure biology ; Hippo pathway ; hippo pathway ; autoimmunity ; Mps one binder ; YAP/TAZ ; GPCR ; fibrosis ; MST1/2 ; YAP (yes-associated protein) ; YAP ; Yap ; protein kinase ; LATS (large tumor suppressor kinase) ; peripheral nerve sheath tumor ; signal cross-talk ; stem cell ; skin development ; STK38 ; tumorigenesis ; NDR ; schwannoma ; G protein-coupled receptor ; anti-cancer therapy ; feedback loops ; vascular mimicry ; castration resistance ; chromatin ; Hippo signalling ; ECM ; MST ; prostate cancer ; TEAD ; cancer ; zebrafish ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
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  • 93
    Publication Date: 2024-03-29
    Description: The visual system consists of hierarchically organized distinct anatomical areas functionally specialized for processing different aspects of a visual object (Felleman & Van Essen, 1991). These visual areas are interconnected through ascending feedforward projections, descending feedback projections, and projections from neural structures at the same hierarchical level (Lamme et al., 1998). Accumulating evidence from anatomical, functional and theoretical studies suggests that these three projections play fundamentally different roles in perception. However, their distinct functional roles in visual processing are still subject to debate (Lamme & Roelfsema, 2000). The focus of this Research Topic is the roles of feedforward and feedback projections in vision. Even though the notions of feedforward, feedback, and reentrant processing are widely accepted, it has been found difficult to distinguish their individual roles on the basis of a single criterion. We welcome empirical contributions, theoretical contributions and reviews that fit into any one (or a combination) of the following domains: 1) their functional roles for perception of specific features of a visual object 2) their contributions to the distinct modes of visual processing (e.g., pre-attentive vs. attentive, conscious vs. unconscious) 3) recent techniques/methodologies to identify distinct functional roles of feedforward and feedback projections and corresponding neural signatures. We believe that the current Research Topic will not only provide recent information about feedforward/feedback processes in vision but also contribute to the understanding fundamental principles of cortical processing in general.
    Keywords: BF1-990 ; Q1-390 ; projections ; processes ; Feedback ; Vision ; feedforward ; Visual System ; mechanisms ; bic Book Industry Communication::J Society & social sciences::JM Psychology ; thema EDItEUR::J Society and Social Sciences::JM Psychology
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  • 94
    facet.materialart.
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In impulse-based manufacturing technologies, the energy required to form, join or cut components acts on the workpiece in a very short time and suddenly accelerates workpiece areas to very high velocities. The correspondingly high strain rates, together with inertia effects, affect the behavior of many materials, resulting in technological benefits such as improved formability, reduced localizing and springback, extended possibilities to produce high-quality multi material joints and burr-free cutting. This Special Issue of JMMP presents the current research findings, which focus on exploiting the full potential of these processes by providing a deeper understanding of the technology and the material behavior and detailed knowledge about the sophisticated process and equipment design. The range of processes that are considered covers electromagnetic forming, electrohydraulic forming, adiabatic cutting, forming by vaporizing foil actuators and other impulse-based manufacturing technologies. Papers show significant improvements in the aforementioned processes with regard to: Processes analysis; Measurement technique; Technology development; Materials and modelling; Tools and equipment; Industrial implementation.
    Keywords: magnetic pulse welding ; spot welds ; linear coils ; shear lap test ; automotive alloys ; numerical analysis ; LS-DYNA ; impact deformation ; vaporizing foil actuator ; powder compaction ; spallation ; inclined collision welding ; dissimilar material combinations ; impact velocity ; impact angle ; collision velocity ; impulse forming ; bulge forming ; permeability ; conductivity ; adiabatic blanking ; adiabatic shear band ; high velocity ; clearance ; blanked surface ; stress triaxiality ; FE simulation ; electromagnetic forming ; proximity effect ; Lorentz forces ; coil windings ; electro-hydraulic ; pulsed forming ; numerical simulation ; preforming ; collision welding ; impact welding ; welding window ; aluminum and copper ; high-speed imaging ; jet ; cloud of particles ; energy balance ; energy extraction ; melting ; material properties ; interface morphology ; magnetic pulse welding (MPW) ; AA6016 ; aluminum ; 22MnB5 ; press-hardening steel ; interface characterization ; mechanical characterization ; tribological characterization ; high strain rate ; elevated temperature ; additive manufacturing ; 18Ni300 maraging steel ; constitutive modelling ; damage modelling ; machining simulation ; magnetic pulse forming ; electro-hydraulic forming ; high strain rates ; lightweight ; high pulsed power ; formability ; simulation ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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  • 95
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This book presents the results of the successful Sensors Special Issue on Intelligent Vehicles that received submissions between March 2019 and May 2020. The Guest Editors of this Special Issue are Dr. David Fernández-Llorca, Dr. Ignacio Parra-Alonso, Dr. Iván García-Daza and Dr. Noelia Parra-Alonso, all from the Computer Engineering Department at the University of Alcalá (Madrid, Spain). A total of 32 manuscripts were finally accepted between 2019 and 2020, presented by top researchers from all over the world. The reader will find a well-representative set of current research and developments related to sensors and sensing for intelligent vehicles. The topics of the published manuscripts can be grouped into seven main categories: (1) assistance systems and automatic vehicle operation, (2) vehicle positioning and localization, (3) fault diagnosis and fail-x systems, (4) perception and scene understanding, (5) smart regenerative braking systems for electric vehicles, (6) driver behavior modeling and (7) intelligent sensing. We, the Guest Editors, hope that the readers will find this book to contain interesting papers for their research, papers that they will enjoy reading as much as we have enjoyed organizing this Special Issue
    Keywords: tracking-by-detection ; multi-vehicle tracking ; Siamese network ; data association ; Markov decision process ; driving behavior ; real-time monitoring ; driver distraction ; mobile application ; portable system ; simulation test ; dynamic driving behavior ; traffic scene augmentation ; corridor model ; IMU ; vision ; classification networks ; Hough transform ; lane markings detection ; semantic segmentation ; transfer learning ; autonomous ; off-road driving ; tire-road forces estimation ; slip angle estimation ; gauge sensors ; fuzzy logic system ; load transfer estimation ; simulation results ; normalization ; lateral force empirical model ; driver monitor ; lane departure ; statistical process control ; fault detection ; sensor fault ; signal restoration ; intelligent vehicle ; autonomous vehicle ; kinematic model ; visual SLAM ; sparse direct method ; photometric calibration ; corner detection and filtering ; loop closure detection ; road friction coefficient ; tire model ; nonlinear observer ; self-aligning torque ; lateral displacement ; Lyapunov method ; automatic parking system (APS) ; end-to-end parking ; reinforcement learning ; parking slot tracking ; deceleration planning ; multi-layer perceptron ; smart regenerative braking ; electric vehicles ; vehicle speed prediction ; driver behavior modeling ; electric vehicle control ; driver characteristics online learning ; objects’ edge detection ; stixel histograms accumulate ; point cloud segmentation ; autonomous vehicles ; scene understanding ; occlusion reasoning ; road detection ; advanced driver assistance system ; trajectory prediction ; risk assessment ; collision warning ; connected vehicles ; vehicular communications ; vulnerable road users ; fail-operational systems ; fall-back strategy ; automated driving ; advanced driving assistance systems ; illumination ; shadow detection ; shadow edge ; image processing ; traffic light detection ; intelligent transportation system ; lane-changing ; merging maneuvers ; game theory ; decision-making ; intelligent vehicles ; model predictive controller ; automatic train operation ; softness factor ; fusion velocity ; online obtaining ; hardware-in-the-loop simulation ; driving assistant ; driving diagnosis ; accident risk maps ; driving safety ; intelligent driving ; virtual test environment ; millimeter wave radar ; lane-change decision ; risk perception ; mixed traffic ; minimum safe deceleration ; automated driving system (ADS) ; sensor fusion ; multi-lane detection ; particle filter ; self-driving car ; unscented Kalman filter ; vehicle model ; Monte Carlo localization ; millimeter-wave radar ; square-root cubature Kalman filter ; Sage-Husa algorithm ; target tracking ; stationary and moving object classification ; localization ; LiDAR ; GNSS ; Global Positioning System (GPS) ; monte carlo ; autonomous driving ; robot motion ; path planning ; piecewise linear approximation ; multiple-target path planning ; autonomous mobile robot ; homotopy based path planning ; LiDAR signal processing ; sensor and information fusion ; advanced driver assistance systems ; autonomous racing ; high-speed camera ; real-time systems ; LiDAR odometry ; fail-aware ; sensors ; sensing ; percepction ; object detection and tracking ; scene segmentation ; vehicle positioning ; fail-x systems ; driver behavior modelling ; automatic operation ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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    Publication Date: 2024-04-05
    Description: The eBook "Building Strategies for Porcine Cancer Models" presents a series of articles demonstrating the state-of-the-art developments in pig models for cancer research. Renowned researchers dedicated to the reproduction, genomic and biological engineering of the pig model for biomedicine contribute to this special research area. Although advances in these areas are occurring at surprising speeds, they are still far from realizing all the potential benefits that this biological model could provide to science. The current biomedical models may limit the frontier of knowledge in the cancer research.
    Keywords: QH426-470 ; Q1-390 ; Pigs ; Cloning ; Genetic engineering ; Comparative Genomics ; Gene Editing ; Animal Models ; Cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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  • 97
    Publication Date: 2024-04-05
    Description: This e-book summarizes recent advances in the young and rapidly developing field of microbial volatiles. Articles included here reveal novel information about the chemical diversity of bacterial and fungal volatiles, their functions, their roles in inter-specific and inter-kingdom interactions and the metabolic and physiological changes their exposure causes in the target organisms. The e-book is divided in three chapters: (1) Natural Functions of Microbial Volatiles; (2) Volatile Production and Ecosystem Functioning and (3) Volatile Detection and Identification.
    Keywords: QR1-502 ; Q1-390 ; microorganisms ; infochemicals ; natural functions ; induced systemic resistance ; Plants ; antimicrobials ; plant growth promotion ; volatiles ; interactions ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-03-27
    Description: Phytochemicals from natural products are now widely used as food additives (antioxidants, pigments), food supplements, cosmetic ingredients, etc. Currently, the majority of the extraction processes implemented on an industrial scale for the production of bioactive-enriched extracts are based on solvents of petroleum origin. However, contemporary trends in green extraction techniques dictate a minimization of solvent use, low-energy processes and novel eco-friendly materials that are environmentally benign. The search for liquids and/or extraction technologies that could meet such requirements is, therefore, an intriguing concept. This book addresses the concept of recovering natural bioactive substances from plant resources, using state-of-the-art extraction technologies, with prospects in the food, cosmetic and pharmaceutical industries.
    Keywords: cosmeceutical product ; long-lived trees ; simplex-centroid mixture design ; deep eutectic solvents ; bioactivity ; flavonoids ; extraction ; deep eutectic solvents (DES) ; natural deep eutectic solvents (NaDES) ; Moringa oleifera ; polyphenols ; ultrasonication pretreatment ; antioxidants ; hydroxypropyl β-cyclodextrin ; potato peels ; grape seed ; grape skin ; green extraction ; antioxidant activity ; chlorogenic acid ; caffeine ; β-cyclodextrin ; coffee pulp ; sensory analysis ; cold brew ; n/a ; thema EDItEUR::G Reference, Information and Interdisciplinary subjects::GP Research and information: general
    Language: English
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  • 99
    Publication Date: 2024-04-05
    Description: Planting trees in the agricultural landscape, in the form of establishing agroforestry systems, has a significant role to play in potentially improving ecosystem services, such as increased biodiversity, reduced soil erosion, increased soil carbon storage, improved food security and nutrition, and reduced greenhouse gas emissions. While the role of trees in agroforestry systems in improving ecosystem services has been researched, studies in new systems/regions and new agroforestry system designs are still emerging. This Special Issue includes selected papers presented at the 4th World Congress on Agroforestry, Montpellier, France 20–22 May 2019, and other volunteer papers. The scope of articles includes all aspects of agroforestry systems.
    Keywords: QH301-705.5 ; Q1-390 ; S1-972 ; farmers’ knowledge ; ahannon-wiener index ; economic benefits ; alley cropping ; lignin ; shelterbelts ; agroforestry ; natural capital ; forest farming ; nutrient content ; agroforestry system ; review ; Amazonia ; cropland ; riparian buffers ; climate change ; subtropical acidic forest soil ; bees ; phosphorus ; pollination ; 15N tracing experiment ; stable isotope ; West Java ; interspecific competition ; growth form ; cropping system ; climate change mitigation ; gross N transformation rates ; East Africa ; improved-fallow ; N-fixing trees ; carbon sequestration ; home garden ; margalef index ; windbreaks ; leaf nutrient diagnosis ; agroforestry systems ; pollinators ; sorption ; forestland ; China ; temperature change ; fractionation ; hedgerows ; native trees ; slash-and-mulch ; soil N ; shade tree species ; soil C ; Alpinia oxyphylla ; sustainable management ; plant water use ; rubber-based agroforestry system ; ecosystem services ; Indonesia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    Unknown
    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Physical processes are keys for the status of a lake. In this Special Issue, the emphasis is on dissolved oxygen and on exchange of gases, energy and momentum between atmosphere and further mixing and consumption within the water. The studies presented relate to ice-free as well as ice-covered lakes. Field measurements are combined with theoretical approaches.
    Keywords: hydrodynamic model ; bubble plume ; artificial mixing ; GLM ; Si3D ; dissolved gas ; Henry law ; total gas pressure ; ebullition ; greenhouse gases ; lacustrine waters ; diurnal variation ; hourly model ; water temperature ; dissolved oxygen ; shallow lakes ; and sediment heat flux ; water quality ; chlorophyll-a ; phosphorus ; phosphorus release ; full set of turbulent stresses ; Acoustic Doppler current profilers ; interbeam velocity correlations ; ice-covered lakes ; convectively-mixed layer ; anisotropic turbulence ; shallow lake ; ice-covered period ; ice phenology ; snow-ice cover thickness ; under-ice irradiance ; radiatively driven convection ; climate change ; 3D modelling ; stratification ; bubble plumes ; fractal ; lakes ; mixing ; multi-scale ; turbulence ; energy fluxes ; energy content ; reservoirs ; internal waves ; surface waves ; biogenic turbulence ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
    Language: English
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