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  • bic Book Industry Communication::M Medicine  (1,154)
  • thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues  (1,123)
  • bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues  (828)
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint concerns topics on chemical, functional, and technological features of wheats to obtain wheat-based foods improved in phytochemicals. Genetic materials, from landraces to ancient and modern wheat varieties, characterized for their content of bioactive compounds, were exploited to produce superior staple foods. The study of other species allowed to identify functional ingredients, in wholemeals or in their by-products, useful in the enrichment of formulations for various cereal-based products. Further, in the optic of circular economy, it is of great interest the extraction of bioactive components from food processing waste belonging to the other crops to functionalize final products.
    Keywords: durum wheat ; diversity ; pigmented cereals ; phytochemicals ; anthocyanins ; antioxidant activity ; protein ; gluten ; wheat aleurone ; dietary fibre ; extraction process ; antioxidant ; bread ; arabinoxylans ; bakery ; biologically active substances ; DPPH assay ; nutritional value ; sensory properties ; pasta fortification ; hemp flour ; durum wheat cultivar ; amino acids ; fatty acids ; mineral fortification ; brewers’ spent grain ; bread-making ; circular economy ; common wheat ; emmer ; phenolics ; proteins ; sustainable food production ; bread wheat ; spelt ; fibre ; metabolites ; minerals ; fertilisation ; health benefits ; colour ; farinograph ; rheofermentograph ; viscoelastic behaviour ; bread shelf life ; crumb porosity ; cereals ; wholemeal ; biscuits ; phenolic acid compositions ; carotenoids ; consumer acceptance ; wheat quality ; genetic resources ; ancient wheat ; avocado wastes/by-products ; functional bread ; lactic acid bacteria ; sourdough ; peels ; pulp ; seeds ; polyphenols ; antioxidant properties ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
    Language: English
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Smart materials and structures are capable of active or passive changes in terms of shapes, properties, and mechanical or electromagnetic responses in reaction to an external stimulus, such as light, temperature, stress, moisture, pH, and electric or magnetic fields. They have attracted increasing interest for their enhanced performance and efficiency over a wide range of industrial applications, especially for aerospace. These require novel engineering approaches and design philosophies in order to integrate the actions of sensors, actuators, and control circuit elements into a single system that can respond adaptively to its surroundings. This reprint has collected cutting-edge research and recent advances in smart materials and structures, including seven original research papers and three review articles, co-authored by 65 scientists and engineers from 18 institutions and 3 industries. The research topics mainly cover advanced materials, applications of smart materials and structures, as well as recent development in sensing techniques. We hope this reprint will contribute to disseminating the latest progress in smart materials and structures, as well as stimulate the interest of its audience to work in this important and vibrant area to promote and benefit the multidisciplinary scientific communities.
    Keywords: textile-based mechanical sensors ; mechanism ; preparation ; advantages ; applications ; Artificial Neural Network (ANN) ; guided waves ; Structural Health Monitoring (SHM) ; Finite Element Analysis (FEA) ; damage detection ; metals ; composites ; aeroelastic stability ; bladed disk ; intentional mistuning ; piezoelectric material ; topological optimization ; microstructure ; high-entropy alloy ; mechanical property ; bipedal robot ; dynamics simulation ; MRE isolator ; vibration reduction control algorithms ; no-core fiber ; polyaniline ; polyacrylic acid ; pH sensor ; multimode interference ; gas foil bearing ; Inconel alloy ; sensing foil ; strain field ; temperature field ; thermomechanical coupling ; thermomechanical characterization ; rotor dynamics ; turbomachinery ; cholesteric liquid crystals ; electro-optic response ; polymer stabilization ; ion-trapping mechanism ; liquid metal ; stretchable conductor ; 3D printing ; high dynamic stability ; wearable devices ; biomimetic ; Venus flytrap ; smart ; composite ; mechanics ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, recent advancements in the field of pediatric tumors are discussed, and novel prognostic markers are critically appraised. Greater understanding of the heterogeneity of pediatric cancers will ultimately lead to new therapeutic strategies with the potential to provide new prospects for precision medicine in pediatric oncology.
    Keywords: undernutrition ; obesity ; nutritional status ; childhood cancer ; overall survival ; event-free survival ; relapse ; treatment-related toxicity ; review ; sarcoma botryoides ; fertility-sparing surgery ; embryonal rhabdomyosarcoma ; genital tract ; prognosis ; treatment ; local debulking ; neoadjuvant chemotherapy ; radiation ; ovarian cancer ; adolescents ; diagnosis ; therapy ; guidelines ; children ; papillary thyroid cancer ; proto-oncogene B-raf gene (BRAF) ; craniopharyngioma ; recurrence ; risk factors ; youth ; acute lymphoblastic leukemia (ALL) ; child ; genetics ; CDKN2A/2B deletions ; fluorescent in situ hybridization (FISH) ; multiple-ligation probe amplification (MLPA) ; copy-number alterations (CNAs) ; risk stratification ; minimal residual disease (MRD) ; cardiotoxicity ; chemotherapeutics agents ; biomarkers ; omics technology ; medulloblastoma ; tumor ; histologic ; pediatrics ; micro-RNAs ; non-coding RNAs ; molecular subgroup ; stratification ; acute lymphoblastic leukemia ; proteomics ; oncology ; chemotherapy ; cardiac function tests ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Agricultural production management is facing a new era of intelligence and automation. With developments in sensor technologies, the temporal, spectral, and spatial resolution from ground/air/space platforms have been notably improved. Optical sensors play an essential role in agriculture production management. Specifically, monitoring plant health, growth conditions, and insect infestation has traditionally involved extensive fieldwork. We believe that sensors, artificial intelligence, and machine learning are not simply scientific experiments but opportunities to make our agricultural production management more efficient and cost-effective, further contributing to the healthy development of natural–human systems. This reprint compiles the latest research on optical sensors and machine learning in agricultural monitoring, including related topics: Machine learning approaches for crop health, growth, and yield monitoring; Combined multisource/multi-sensor data to improve the crop parameters mapping; Crop-related growth models, artificial intelligence models, algorithms, and precision management; Farmland environmental monitoring and management; Ground, air, and space platforms application in precision agriculture; Development and application of field robotics; High-throughput field information survey; Phenological monitoring.
    Keywords: soil moisture content ; spectral processing technology ; hyperspectral ; principal component analysis ; feature parameters extraction ; yield estimation ; rice ; unmanned aerial vehicle (UAV) ; tasseled cap transformation ; precision agriculture ; weed identification ; YOLOv4-Tiny ; attention mechanism ; multiscale detection ; angle normalization ; vegetation canopy reflectance ; geostationary satellite ; path length correction ; Minnaert model ; GOCI ; winter wheat ; LSTM ; LAI ; deep learning ; land use ; land cover ; classification ; random forest ; Sentinel data ; SRTM ; feature selection ; accuracy ; validation ; unmanned aerial vehicle ; soybean ; convolutional neural network ; multispectral imagery ; fusarium head blight ; texture indices ; machine learning ; cropland ; multi-seasonal ; fractal feature ; feature extraction ; accuracy evaluation ; black soil ; UAV ; chlorophyll ; fractional vegetation cover ; maturity monitoring ; anomaly detection ; smart agriculture ; detection of apple leaf diseases ; YOLOv5 ; transformer ; CBAM ; crop type classification ; multi-temporal ; remote sensing ; dairy cows ; body condition score ; 3D TOF sensor ; non-contact evaluation ; recognize area of interest ; sugarcane clones ; canopy cover ; light interception ; biomass ; cane yield ; peanut southern blight ; reflection spectrum ; spectral index ; continuous wavelet transform ; VGNet ; corn diseases ; leaf detection ; lightweight ; transfer learning ; agriculture ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Land degradation, exacerbated by climate change and rapid urbanization, poses significant threats to socio-economic development. There is an urgent need to explore land degradation and its associated ecosystem responses and the suitable pathways for sustainable development in urban and rural regions. This reprint comprises a collection of 16 articles, featuring 1 review article and 15 research articles. There are some key practical experiences and scientific findings to support the ecosystem change response to land degradation, through either theoretical works or empirical research, identifying the characteristics and solutions for sustainable development. Key scientific issues addressed include land use and land cover change, ecological impacts of urbanization, mechanisms of land degradation on ecosystems, and coordinated social, economic, and ecological development. This reprint encouraged scholars to share the latest advancements in the research framework, datasets, methods, and case studies for assessing land degradation and associated ecosystem responses. We expect this reprint will inspire broader reflection and discussion within academic community regarding the theories and practices concerning land degradation and associated ecosystem responses. It could be a valuable reference for exploring potential solutions towards achieving land degradation neutrality and promoting regional sustainable development.
    Keywords: ecological compensation ; ecosystem services ; opportunity cost ; ecological compensation priority ; land degradation ; dust emission ; wind erosion ; dust models ; dust cycle ; carbon cycle ; livestock carrying capacity risk ; planting and breeding balance ; northeast China ; farmland circulation ; differential circulation features ; driving mechanism ; plot level ; plains and mountainous areas ; Zhangye City ; ecological carrying capacity ; supply and demand ; priority areas ; agricultural ecological efficiency ; spatial-temporal evolution ; SBM model ; spatial Markov chain ; spatiotemporal changes ; driving factors ; agro-pastoral transitional zone ; management ; Bashang Plateau ; Populus simonii forest ; optimal plant cover ; leaf-area index ; Biome-BGC model ; urban resilience ; land use/cover change ; urbanization ; carbon neutrality ; Beijing-Tianjin-Hebei urban agglomeration ; surface thermal environment ; standard deviation ellipse ; Shijiazhuang ; wildfires ; natural protected areas ; decision support system ; scenario-based analysis ; soil salinity ; sodicity ; GIS ; RS ; leaching and gypsum requirement ; carbon and nitrogen pools ; soil quality ; carbon and nitrogen management index ; land use ; arid environment ; eco-compensation ; ecosystem service value ; PAHs pollution ; risk assessment ; industrial legacy sites ; vertical distribution ; land reuse ; drylands ; sediment connectivity ; degradation ; land use and land cover change (LULCC) ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Recently, the trends of a circular economy and sustainability have driven nanotechnology towards the development of novel and innovative applications in the food packaging sector, which is rather recent compared with their use in biomedical and pharmaceutical applications. Bioactive films and coatings based on natural biopolymers such as chitosan, sodium alginate and gelatin and containing antioxidant and antimicrobial agents such as micro- and nanoemulsions of phytochemicals and nanostructured materials such as quantum dots, ZnO nanoparticles, nanoclays, silicas, zeolites and activated carbons, are finding application in various sectors of the food industry, especially in the development of novel edible, active packaging films and coatings. These bioactive films and coating materials enhance solubility, improve bioavailability, facilitate controlled release, and protect bioactive components during manufacture and storage. This Issue intends to provide an overview of bioactive gel films and coatings applied in active food packaging.
    Keywords: bioactive packaging ; xanthan ; propolis ; physicochemical properties ; microbiological analyses ; sensory evaluation ; biopolymers ; antimicrobial ; environment ; film ; coating ; active packaging ; soft cheese preservation ; sodium alginate ; thyme oil ; natural zeolite ; shelf-life extension ; anthocyanin ; fruit decay ; postharvest shelf life ; Aloe vera ; antioxidant ; fig ; purple-flesh sweet-potato ; chitosan ; gel coating ; preservation ; citrus ; cinnamon ; clove ; eucalyptus ; mint ; ginger ; chamomile ; halloysite ; polyvinyl alcohol ; gel ; active coatings ; nanostructures ; kiwi fruits ; green pea pods ; corn oil ; films ; hydrogel polymer ; acacia gum ; cinnamon essential oil ; edible hydrogel-based films ; food packaging ; edible films ; composite material ; essential oil ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Metronomic chemotherapy is now, finally, in clinical use. After 20 years of preclinical development and clinical trials, the emerging data will be of paramount importance in allowing us to assess the impact of metronomic chemotherapy on different tumor types. Indeed, it is likely that the next decade will see a major reassessment of the possible applications of metronomic chemotherapy, both alone and in combination with new therapeutic approaches such as immunotherapies, for the management of cancer. Moreover, the results of clinical trials will likely profoundly affect the direction of the laboratory efforts that are going on in parallel and aiming to improve the personalization of this therapeutic strategy. This Special Issue is our attempt to cover the past and present clinical results that have brought us to this pivotal moment and will form the basis of future clinical developments. Scientists and clinicians caring for cancer patients are well aware of the challenges in dealing with this particular therapeutic approach; one such challenge is obtaining improvements in patient survival without significant toxicity. This edition includes clinical research on chemotherapy and ongoing controversies related to metronomic chemotherapy.
    Keywords: metronomic ; oral cancer ; oral squamous cell carcinoma ; metronomic chemotherapy ; metastatic castration-resistant prostate cancer ; cyclophosphamide ; side effects ; pediatric tumors ; etoposide ; valproic acid ; prostate cancer ; CRPC ; castration ; capecitabine ; paclitaxel ; immunomodulation ; angiogenesis ; microbiome ; breast cancer ; safety ; preclinical studies ; clinical studies ; pharmacokinetic studies ; biomarkers ; chemo-free ; DLBCL ; diffuse-large-b-cell-lymphoma ; elderly ; frail ; comprehensive geriatric assessment ; chemo-endocrine therapy ; FulVEC ; pediatric oncology ; brain tumors ; pharmacology ; medulloblastoma ; ATRT ; immunotherapy ; lymphoma ; vinorelbine ; checkpoint inhibitors ; bic Book Industry Communication::M Medicine
    Language: English
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The integration of information technologies with industry has marked the beginning of the fourth industrial revolution and promoted the development of industrial engineering. However, the depletion of resources and industrial waste caused by increasing amounts of industrial production pose a huge threat to nature. The application of sustainable supply chains in industrial engineering and management is one of the ways to balance the economy, society and environment. Therefore, it is a key concern for us to explore the construction of sustainable supply chains in industrial engineering and management. Moreover, to understand the impact of low-carbon, sustainable and recycled supply chains on industrial engineering, we need more in-depth investigations.This Special Issue aims to solicit original research and review articles discussing sustainable supply chain decision-making in industrial engineering and management to improve the sustainability of enterprise operations. Moreover, this Special Issue also shows mixed methods (e.g., modeling plus a case study) and rigorous quantitative/qualitative empirical studies of sustainable supply chains.
    Keywords: coordination degree model ; logistics industry ; digital economy ; industrial integration ; regional IEE system ; multimodel decision ; coupling coordination ; decision support methods ; online retailer ; consumer purchase behavior ; return strategy ; return insurance ; supply chain management ; real-time ; home delivery ; business modeling ; e-commerce ; time window ; lightweight ; carbon emissions ; low carbon benefits ; optimization design ; wheel hub ; subsidy policy ; remanufacturing industry ; donation strategy ; prisoner’s dilemma ; water-efficient products ; quality improvement ; DMAIC ; smart water closets ; carbon abatement ; cost sharing ; capital constraint ; environmental externality ; innovative products ; remanufacturing ; differential game ; bass model ; strategic emerging industries ; industrial structure ; employment effect ; artificial intelligence hardware ; data classification ; deep learning ; emission control ; industrial manufacturing ; bilateral matching decision making ; interval-valued hesitant fuzzy information ; bidirectional projection technology ; organizational quality-specific immunity ; automotive supply chain disruption ; supply chain resilience ; disruption risk ; bibliometric analysis ; co-citation analysis ; NGU ; self-attention ; CNN ; silver prediction ; data-driven ; composite systems ; synergy ; sustainability ; blockchain ; collection channel ; recycling strategies ; uncertain demand ; game theory ; federated learning ; intelligent manufacturing ; sustainable energy ; low-carbon strategy ; livestreaming marketing mode ; consumer low-carbon preference ; level of low-carbon promotion effort ; power structures ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The states of bridge structures decline over time due to various degradation processes, such as creep, corrosion, and cyclic loading. During its life cycle, a bridge also faces the great threat of multiple hazards, such as winds, earthquakes, collisions, waves, landslides, and so on. Structural damages in an existing bridge affect operational and structural safety and weaken the sustainability of bridges. Therefore, advanced damage diagnosis techniques and safety assessment methods are strongly required to ensure structural safety and achieve infrastructure sustainability. This Special Issue aims to bring together recent scientific developments in probabilistic hazard analysis, structural exposure models, damage diagnosis methods, testing and measurement techniques, dynamic behavior and protection technology, damage mechanisms, risk assessment framework, and resilience-based approaches. Since we have past one year since this Special Issue opened, thirteen papers have been published, the majority of which focus on the structural safety assessment of bridges under wind, earthquake, collision, wave, etc. The Guest Editors believe that this reprint will provide important theoretical and technical support for bridge damage diagnosis and safety assessment and promote communication and cooperation between design, construction, research, teaching, and production.
    Keywords: self-consolidating concrete ; micro-steel fiber ; high admixture ; mechanical performance ; grid pile foundation ; ABAQUS ; load-bearing performance ; Monte Carlo method ; safety assessment ; sea-crossing bridges ; triangle elevation ; leveling method ; dynamic compensation ; total station ; harsh environment ; long distance ; sea-crossing elevation ; combined survey platform ; numerical simulation ; strong wave and deep-water conditions ; wave-current load ; working performance ; arch bridge ; ultimate span length ; theoretical analysis ; high-performance material ; strength ; stability ; bridge ; near-fault earthquake ; vertical separation ; eccentric impact ; failure mode ; pounding ; prefabricated frame bridge ; seismic behaviors ; small and medium bridge ; seismic responses ; stopper damage ; numerical method ; conformal mapping ; closed box girder ; sliding searching method ; flutter performance ; aerodynamic forces ; streamlined box girder ; coupled vibration ; potential flow ; second-order component ; bridge engineering ; temperature gradient ; parameter sensitivity ; steel slag ; concrete-filled double-skin steel tube (CFDST) ; T-joint ; seismic performance ; concrete-filled steel tubular (CFST) ; laced piers ; modeling method ; design optimization ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 10
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Rapid urbanization and industrialization, in addition to the presence of new pollutants, make it necessary to search for new wastewater treatment technologies to achieve future water quality requirements. Additionally, waste reduction and the reuse of treated wastewater seem to be excellent options to realize the concept of a circular economy. This Reprint compiles the latest research on relevant wastewater treatment concerns, including the occurrence of emerging contaminants and their removal in wastewater treatment plants (WWTPs), novel technologies for wastewater and sludge treatment, sludge valorization, the transformation of agricultural residues into materials for wastewater treatment, biodegradation of recalcitrant compounds, etc.
    Keywords: wastewater treatment ; emerging pollutants ; agricultural waste valorization ; biodegradation ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: With the continuous improvement of artificial intelligence and sensing technologies, the marine field is ushering in unprecedented change. In this wave of change, the design and application of marine transportation have become significant tools for promoting the marine economy and environmental protection. Motion control and path planning have become key technologies to ensure that marine transportation vehicles operate efficiently and intelligently in complex marine environments. Therefore, this Special Issue focuses on motion control and path planning for marine vehicles and explores how autonomous underwater vehicles (AUVs), surface unmanned vehicles (USVs), and deep-sea landers (DSLVs) can play a key role in the oceans through optimization strategies and new approaches. We will delve into the application of intelligent and autonomous motion control systems on marine vehicles, and the innovation and optimization of path-planning techniques. In this Special Issue, we brought together the latest results from experts and researchers, aiming to share their cutting-edge research in motion control and path planning for marine vehicles. We expect that the presentation of these papers will provide new ideas and solutions to promote marine science and technology development and application. Finally, we would like to convey our most profound gratitude to the staff of MDPI Books and the editorial team of Marine Science and Engineering, in particular the assistant editors, talented authors, and diligent reviewers.
    Keywords: motion control ; path planning ; ship motion ; marine vehicle ; unmanned ocean vehicles ; autonomouslearning and AI ; cooperation and coordination ; unmanned marine vehicle swarm ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The vast number of recently published research papers on computational and numerical methods for solving various structural problems proves that this topic has great potential, and the further advancements that can be accomplished are still numerous.This reprint contains innovative investigations dealing with accurate, reliable, and effective numerical approaches in the field of both structural mechanics and the mechanics of materials.In particular, these studies present a numerical analysis focused on the development of finite-element or finite-element-based methods for novel problems, as well as different computational techniques involving the solution of those problems that require the development of numerical methods to obtain approximate but accurate solutions.In any circumstance, the contributing authors have emphasized the novelty of their approaches, highlighting the improvements with respect to the existing literature. Much attention has also been dedicated to the numerical investigations of advanced and innovative materials, as well as multiscale analyses, employed in many engineering fields, such as civil, mechanical, and aerospace engineering.
    Keywords: Computational mechanics ; Numerical methods ; Advanced and innovative constituents ; Solids mechanics ; Structural analyses ; FE and FE-based methods ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TN Civil engineering, surveying and building::TNK Building construction and materials::TNKX Conservation of buildings and building materials
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  • 13
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In human social development, the consumption of fossil energy, especially coal, has promoted economic prosperity, cultural exchanges, and social progress. With shallow coal resources exhausted, coal mining engineering has entered deep areas. The coal geology environment of the deep area differs from that of the shallow. With mining depth increasing, all the stress of buried rock stratum and surrounding rock and gas pressure of coal seam increase gradually. In addition, geological structures, such as complex faults, big folds, and thick-hard roofs, will increase the risk of coal mining. Once the dynamic disaster occurs, it will induce miner casualties and property losses. So, it is urgent to identify mine hazards, such as coal and gas outbursts, rock bursts, gas explosions, and coal fires, and research their formation mechanism, occurrence, and development process. Furthermore, prevention and control methods should be proposed to reduce mine disasters. Only in this way can we promote the safe, green, and efficient development of coal mining. This Topical Collection, titled “Mine Hazards Identification, Prevention, and Control,” aims to allow global researchers to conduct a broader scientific and technological discussion on such advances to improve the prevention and control level of disasters encountered during underground coal mining. The discussion topics include, but are not limited to, the basic experiments, modeling, numerical simulation, and field tests of aforementioned disasters.
    Keywords: mine hazards ; coal/rock disasters ; coal and gas outburst ; monitoring and early warning ; prevention and control ; identification method ; gas explosions ; coal fires ; composite dynamic disasters ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This topic reprint "Application of Innovative Power Electronic Technologies" encompasses a diverse range of topics and discoveries that addresses the increasing global demand for energy conversion in the context of sustainable energy, electric vehicles, industrial automation, and smart grids. This reprint brought together a selection of papers that delve into new technologies and practical applications of power electronics, offering insights into the challenges and solutions faced in the design and implementation of advanced energy conversion techniques.
    Keywords: power electronics ; energy conversion ; innovative technologies ; smart grid applications ; electric vehicle integration ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This collection of articles provides insight into the mental health and nursing care of individuals who are confronting a life-threatening illness. As individuals face a cancer diagnosis, there will be many challenges and changes in their lives. Emotional distress can emerge to greater and lesser degrees. Frequently, these individuals will require additional assistance to cope with the emotional distress they experience. Nurses have an important role in assessing this emotional distress and providing relevant interventions.
    Keywords: Latinx ; family ; meaning ; communication ; coping with advanced cancer ; delirium ; liaison nurse ; misrecognition of delirium ; coordination ; breast cancer ; psychological distress ; quality of life ; women’s health ; qualitative study ; cancer care ; older adults ; mental health ; feeling safe ; home-dwelling ; patients with terminal cancer ; caregivers ; competency in anticipatory grief counseling ; emotional care ; person-centered care ; qualitative research ; anxiety ; depression ; family involvement ; hepatocellular carcinoma ; palliative care ; cancer ; decision-making ; nurse ; caregiving self-efficacy ; family caregiver ; oral cancer ; oncology ; nursing ; clinical nurse specialists ; cancer patients ; expanding nurses’ authority ; professionalization ; policy ; education ; bic Book Industry Communication::M Medicine
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Obstructive sleep apnea is a highly prevalent disorder with strong associations with cardiovascular, cerebrovascular, metabolic, and cognitive consequences, including drowsy driving. Positive Airway Pressure treatment is the first-line therapy for adults with obstructive sleep apnea who are symptomatic. However, many individuals with comorbidities do not report symptoms that are associated with the disorder, and adherence to treatment is poor, especially in individuals with cardiovascular diseases. This reprint contains reviews and original articles that aim to update the current perspectives on the treatment modalities of obstructive sleep apnea to highlight multidisciplinary approaches, personalized treatment strategies, and the identification of the predictors of a patient’s response to treatment, both in the general population and in clinical cohorts.
    Keywords: obstructive sleep apnea (OSA) ; continuous positive airway pressure (CPAP) ; mandibular advancement devices ; upper airway surgery ; drowsy driving ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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  • 17
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-09
    Description: This Special Issue reprint highlights seventy years since the discovery of carbon nanotubes (CNTs) in 1952 by Russian scientists LV Radushkevich and VM Lukyanovich in what was then the Union of Soviet Socialist Republics or the USSR. It also reflects the popularization by the well-known Japanese scientist S Iijima, since 1991, of carbon nanostructures, including CNTs, towards nanotechnology as a forever impactful and inspiring field. For researchers, academics, and teachers of all levels, from novice to expert to guru, the articles contained within this Special Issue are themed around sustainability from nanotechnology, pertaining to diameter measurement, rotor system molecular simulation, ultra-high tensile strength, energy, filtration via membrane distillation, environmental remediation using adsorption, ionic liquids as curing agents, biosensors and bioinspired sensors, and electrical/mechanical properties of polymer nanocomposites. The CNT is a legacy 1D nanomaterial, only after which was 2D graphene able to emerge. This is a global and mixed-country authorship Special Issue, with this reprint containing articles from Canada, Saudi Arabia, China, Russia, Spain, India, Japan, the United Arab Emirates (UAE), the USA, Germany, Turkiye, and Malaysia. The Guest Editor is from Singapore and began publishing critical work on the CNT-polymer interface towards the mechanical properties of the nanocomposite up to 20 years ago.
    Keywords: CNTs ; MWCNTs ; SWCNTs ; polymer composite ; mechanical performance ; flexible capacitive sensors ; bioinspired spinosum ; CNT/PDMS nanocomposite ; tires ; transmission system ; carbon nanotube (CNT) ; hydroxyl groups ; response speed ; energy dissipation ; carbon nanotubes ; carbon nanotube fibers ; tensile strength ; defect control ; controlled preparation ; dielectric polymer composites ; permittivity ; polymer nanocomposite ; electrical conductivity ; mixing ; polymer blends ; electromagnetic interference shielding ; carbon nanotube ; filler migration ; polyethylene ; lead ; arsenic ; adsorption ; poly(amidoamine) ; silver nanoparticles ; biosensor ; virus ; SARS-CoV-2 ; toxicity ; biocompatibility ; electrospinning ; electrospraying ; nanomaterials ; nanostructured membrane ; nanocomposites ; seawater desalination ; temperature polarization ; flux ; solar energy ; dye degradation ; surface plasmon resonance effect ; TiO2/rGO/Ag ; hybrid nanostructures ; phosphorus ; encapsulation ; lithium-ion batteries ; atomic force microscopy ; diameter ; nanometrology ; epoxy resin ; ionic liquid ; nanocomposite ; curing agent ; dispersing agent ; mechanical properties ; lap shear ; conductivity ; melt-mixing ; polymer composites ; SWCNT ; PMMA ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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  • 18
    Publication Date: 2024-01-08
    Description: Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management of primary non-response and secondary loss of response to biologics, while cumulative evidence suggests that proactive TDM is efficacious for optimizing anti-tumour necrosis factor (anti-TNF) therapy in patients with IBD. Proactive TDM can be very useful for optimizing biological therapy in specific IBD populations, such as pregnant women as well as patients with perianal fistulizing Crohn’s disease and acute severe ulcerative colitis who are characterized by high drug clearance. Preliminary data suggest that proactive TDM may also have a role in de-escalating anti-TNF therapy in patients in clinical remission including stopping the immunomodulator when combined with anti-TNF therapy. However, several knowledge gaps and limitations hinder the wide implementation of TDM in clinical practice, including the optimal drug concentration to target the lag time between sampling and results and the lack of harmonization of TDM assays. Recent advances regarding the role of TDM include the use of rapid point-of-care assays and the incorporation of model-informed precision dosing. The aim of this Special Issue is to highlight the clinical utility of TDM and discuss the barriers and recent advances of TDM of biologics in IBD and other IMID.
    Keywords: ulcerative colitis ; Crohn&rsquo ; s disease ; inflammatory bowel disease ; infliximab ; adalimumab ; certolizumab pegol ; golimumab ; vedolizumab ; ustekinumab ; therapeutic drug monitoring ; immunogenicity ; rheumatoid arthritis ; ankylosing spondylitis ; psoriasis ; clearance ; model informed precision dosing ; bic Book Industry Communication::M Medicine
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Implementing sustainable development is central to achieving global reductions in greenhouse gas emissions and mitigating anthropogenic environmental impacts. As defined by the UN 2030 Agenda and its associated Sustainable Development Goals (SDGs), sustainable development requires a holistic, interdisciplinary approach, which is not without its challenges. Indeed, studies tracking global progress toward meeting the 2030 SDG targets emphasize the importance of implementing sustainable solutions, with several SDG targets described as 'off track.' Therefore, there is an urgent need to address the challenges of an interdisciplinary, unified, and practical approach to sustainable implementation. In this context, this Reprint brings together 15 selected papers presented during the 2022 SDEWES Conference. These papers cover a broad range of topics, from circular governance models to education related to sustainable practices, as well as the impacts of current legislative frameworks targeting energy efficiency, built environment energy performance, bio-based industrial applications, transport and sustainable energy services, and production, supply, and infrastructure maintenance strategies. This Reprint provides an interdisciplinary and holistic perspective on sustainable development solutions, with several papers highlighting the interrelations between various fields and aspects of sustainability.
    Keywords: combined heat and power ; hospitality ; feasibility ; sensitivity analysis ; simple payback ; energy performance certificate ; CO2 ; multi-apartment buildings ; heating ; energy consumption ; cooling ; performance-based retrofit ; decision support ; building performance simulation ; parametric analysis ; multiple-criteria decision analysis ; residential buildings ; in-line inspection ; smart pig ; sensor ; oil ; natural gas ; pipeline ; environment ; biorefinery ; organosolv ; lignin ; pre-treatment ; higher education ; competencies development ; STEM education ; sustainability ; colloidal particles ; Pickering emulsion ; rheological behaviour ; ESCO business models ; aggregator business models ; energy services for buildings ; energy performance contract ; Pay-for-Performance contract ; energy efficiency in buildings ; demand response ; demand side flexibility ; residential sector ; governance ; circular economy ; circular territories ; index ; circularity ; thermal transmittance ; thermal resistance ; finite element method ; heat flux sensor ; in situ monitoring ; concrete masonry unit ; hydrogen ; water ; wastewater ; electrolysis ; water scarcity ; wastewater treatment plants ; desalination ; Jordan ; system dynamics ; thermal comfort ; Minha Casa Minha Vida ; natural ventilation ; bioclimatic architecture ; social housing ; energy poverty ; battery electric vehicles ; plug-in hybrid electric vehicles ; hybrid electric vehicles ; CO2 emissions ; Hofstede ; advertising ; sustainability integration ; Middle East ; supply chain management ; responsible logistics ; education for SDGs ; natural gas pipelines ; nondestructive testing (NDT) ; in-line inspection robot ; wireless communication ; antenna ; circular waveguide ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Acoustic sensors have been utilized commercially for more than 60 years. Acoustic sensing technologies have been studied extensively and the information, transmission, reception, transformation, processing, and application of acoustic signals have been developed, with acoustic sensors as the central focus. An acoustic sensor is a device that converts a sound wave signal into an electrical signal. This Special Issue on Acoustic Sensors and Their Applications presents original research covering recent advances in all aspects of the design, development, testing, and application of acoustic sensors.
    Keywords: Acoustic&nbsp ; emission ; piezoelectric&nbsp ; transducer ; hybrid acoustic model ; &nbsp ; structural health monitoring ; non-destructive testing ; computational paralinguistics ; pencil lead break test ; leak detection ; optical microphone ; speaker recognition ; thickness measurement ; sound navigation and ranging ; noise control ; infinity tube ; ultrasonic measurement ; air-coupled ultrasound ; ATP system in air ; optical ultrasound detection. ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 21
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the IBD classification are ulcerative colitis (UC) and Crohn’s disease (CD), sharing similarities but exhibiting distinct differences, sometimes making their discrimination challenging.A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by the robust and persistent infiltration of immune cells and compromised intestinal barrier integrity, leading to a phenomenon known as “leaky gut.” Inflammation can manifest acutely or chronically, known as relapsing, and can increase in severity over time, thereby causing life-long morbidities and reduced quality of life for affected individuals, underscoring the need for a deeper comprehension of the molecular contributors to disease pathogenesis and progression.
    Keywords: inflammatory bowel diseases ; cell autofluorescence ; immune cells ; NADH ; FAD ; flow cytometry ; multiphoton microscopy ; colitis ; colitis-associated cancer ; inflammatory bowel disease ; colorectal cancer ; colon adenocarcinoma ; ulcerative colitis ; Crohn’s disease ; cDNA microarray ; transciptomics analysis ; microarray ; inflammatory bowel diseases (IBDs) ; vasculature ; angiogenesis ; gut vascular barrier ; vessel permeability ; epithelial barrier ; homeostasis ; acetylcholine ; muscarinic receptor ; non-neuronal acetylcholine ; mucosal wound healing ; ferroptosis ; leaky gut ; inflammatory bowel disease (IBD) ; triple-culture ; Caco-2 ; HT29-MTX-E12 ; THP-1 ; monocyte-derived macrophage ; inflammation ; TEER ; FITC-dextran 4 kDa (FD4) ; pro-inflammatory cytokines ; HIF-1α ; PHD2 ; AKT ; intestinal epithelial cells ; probiotics ; LPS ; antigen-specific T-cells ; celiac disease ; gliadin ; IBD ; food antigens ; intestinal Behcet’s disease ; immune mechanism ; biological agents ; claudin ; tight junctions ; barrier function ; gut ; ZO-1 ; actin ; cell migration ; cell division ; colon cancer ; PMNs ; LDs ; FOXO3 ; n/a ; bic Book Industry Communication::M Medicine
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  • 22
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The reprint will help young readers discover systematic research and reviews of the various topics in the field of microfluidic-based biosensing. This reprint contains empirical studies and systematic reviews regarding the use of microfluidic technology in biosensing and its applications in point-of-care system development.
    Keywords: Microfluidic Chip ; integrated sensing ; Diagnostic ; Point-of-care. ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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  • 23
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Biomedical sensors stand at the forefront of modern medical technologies, serving as indispensable components in diverse instruments and equipment. These sensors unravel the intricacies of biological processes and medical interventions. The recent surge in high-density sensor systems, characterized by arrangements in matrix arrays and other configurations, has ushered in a new era of functional evaluation. This spans electrophysiological activity, the metabolic responses of organs and tissues, and motor control analysis, all enriched with crucial spatial information. Functional mapping, a burgeoning approach in various biomedical techniques such as EEG, EMG, ECG, NIRS, and MEG, is proving to be transformative. Its integration enhances our comprehension of complex biological behaviors, where the precise spatial localization of sensing methodologies becomes paramount. The applications of functional mapping using biomedical sensors extend across multiple fields, including neuroscience, neuromuscular physiology, rehabilitation, and cardiology. Its utility ranges from diagnostic purposes to assessing the effectiveness of therapeutic interventions. The primary objective of this reprint was to collect papers that delineate the forefront of techniques, methods, and applications in the realm of biomedical sensors. Additionally, the focus extends to specific algorithms for data processing, ensuring a robust understanding of functional information intricately associated with spatial localization.
    Keywords: EMG ; EEG ; rehabilitation ; neuromotor ; evaluation ; assessment ; review ; machine learning ; biofeedback ; transfer learning ; random forest classifier ; COVID-19 ; intubation ; tracheoesophageal fistula ; tracheal lesions ; acute respiratory distress syndrome ; modeling ; intensive care unit ; muscle synergies ; whole body FES ; neurological patients ; photodynamic therapy ; fluorescence ; laser ; fluorophores ; enamel ; effective connectivity ; kurtosis ; resting-state connectivity ; stationarity ; sleep monitoring ; pressure bed sensor (PBS) ; unobtrusive measure ; multi-scale analysis ; sleep apnea–hypopnea syndrome (SAHS) ; shift-working ; optically detected magnetic resonance ; quantum magnetometer ; magnetoencephalography ; time domain ; functional near infrared spectroscopy ; diffuse optics ; brain ; hemodynamics ; resting-state brain oscillation ; mental workload ; signal processing ; reliability ; cognitive performance ; Simon task ; emotion detection ; valence ; arousal ; wearable sensors ; regression ; classification ; technology acceptance model ; rehabilitation exoskeletons ; therapists ; neuro-rehabilitation ; multiple linear regression ; Pearson’s correlation ; integrated sensor systems ; hand function ; hand osteoarthritis ; electromyography ; diagnosis ; discriminant analysis ; photoplethysmogram ; microcirculation ; deep learning ; convolutional neural network ; modelling ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The Special Issue entitled “Advances in Rock Mechanics and Geotechnical Engineering” is devoted to the publication of the latest research, field works, and laboratory investigations in the area of rock mechanics and geotechnical engineering. This Special Issue has published novel contributions in different areas of geotechnical and geomechanical engineering such as slope and embankment, tunneling and underground space technologies, pile and foundation, rock mechanics and rock blasting, excavation and leveling projects, ground improvement techniques, unsaturated soil, practical issues in soft soil, mining technology, geo-environmental engineering, new laboratory testing, applied geology for construction, and novel geotechnical construction methods. The focus of this reprint is on the development of computational methods for solving problems in the fields of rock mechanics and geotechnical engineering.
    Keywords: strength prediction ; brittle rock ; grain-structure representation ; micro-properties ; bonded block models ; Voronoi tessellation ; structure-type rockburst ; evolution mechanism ; particle flow code ; flat-joint model ; pre-grouting ; soft coal mass ; coal-grout structure ; shear behavior ; quality improvement ; rock strength ; tensile behaviour ; neuro-fuzzy ; regression ; non-destructive tests ; paste filling ; slicing mining ; false roof stability ; optimal false roof thickness ; tree-based techniques ; feature selection ; pile bearing capacity ; gradient boosted tree ; random forest ; in situ stress ; rock blasting ; crack propagation ; model test ; rheological deformation ; key stratum ; roadway groups ; roadway deformation ; surrounding rock control ; triaxial creep experiment ; cyclic loading and unloading ; elasto-visco-plastic strain ; irrecoverable strain ; tertiary creep stage ; nonlinear creep damage model ; high-altitude slope ; BP neural network ; freeze-thaw cycle ; geological conditions ; mining method ; soft broken complex ore body ; improved AHP ; comprehensive evaluation index ; blasting ; back-break ; SVM ; metaheuristic algorithms ; moth–flame optimization ; whale optimization algorithm ; tilted strata ; roadway ; nonuniform deformation ; physical simulation ; HFDEM ; numerical method ; rock fracture ; strain rate ; mining engineering ; backfill mining ; high-concentration backfill ; elastic modulus ; K-fold cross-validation ; mining ; rock engineering ; sensitivity analysis ; XGBoost ; limit equilibrium method (LEM) ; limit analysis ; accuracy ; slope stability ; homogenous slopes ; error accuracy classification chart ; physical and mechanical responses ; Egyptian granodiorite ; thermal damage threshold ; microstructure ; thermal constructions ; rock slope analysis ; limited analysis method ; numerical methods ; combined/hybrid finite–discrete element method ; FDEM ; non-renewable ; clean coal technology ; waste of resources ; “110 construction method” ; collapse settlement control ; moisture content ; dry–wet cycles ; cyclic loading ; injury mechanism ; acoustic emission RA-AF ; thermal effect prediction model ; uniaxial compressive strength ; static Young’s modulus ; artificial neural network ; multilinear regression ; rock mass ; hydraulic conductivity ; sustainability ; rock mechanics ; geotechnical engineering ; geomechanical engineering ; mining technology ; natural stones ; temperature ; fire ; thermal effect ; point load strength ; porosity ; color ; gloss ; automated mineral identification ; LBP ; classification ; texture feature ; liquefaction potential ; prediction ; Bayesian optimization ; support vector machines ; optimization ; Hoek–Brown criterion ; Mohr failure envelope ; Balmer’s equation ; limit equilibrium analysis ; modified Bishop approach ; active earth pressure ; unsaturated narrow backfill ; interlayer shear stress ; arching effect ; thin-layer element method ; tunnel excavation ; cut blasting method ; LLB method ; uncharged hole ; numerical simulation ; spectrum index ; water content ; hyperspectral information ; V-type firing pattern ; collision fragmentation ; RSA ; ANN ; coupled stress-hydro effect ; uniaxial loading ; infrared radiation ; warning threshold ; non-destructive monitoring ; alteration ; tunnel ; stress field ; deformation field ; plastic zone ; flyrock ; weathering index (WI) ; equilibrium optimizer (EO) ; particle swarm optimization (PSO) ; extreme learning machine (ELM) ; artificial neural network (ANN) ; high-water material ; seawater ; water-cement ratio ; strength ; mining method optimization ; difficult-to-mine complicated orebody ; multiple attribute decision making ; Pythagorean fuzzy sets and TOPSIS method ; mechanized upward horizontal layering method ; plateau alluvial-lacustrine deposits ; round gravelly soil ; large scale direct shear test ; shear strength parameters ; Erbil ; geotechnical characterization ; GIS ; ANFIS ; differential evolution ; firefly algorithm ; frozen rock mass blasting ; ice-filled crack ; explosion stress wave propagation ; attenuation factor ; UCS ; intelligent and statistical methods ; sedimentary rocks ; modulus of deformation ; RMR ; in situ testing ; modelling ; instrumentation ; failure risk ; element failure probability ; spatial variability ; stochastic groundwater level ; upper bound method ; rock joints ; shear strength ; scale effects ; normal stress ; JRC ; PFC simulation ; water inrush ; precursor ; strain energy ; normalized ; sustainable mine ; blast-induced flyrock ; LSSVM ; prediction models ; salt cavern ; underground gas storage ; continuum-discrete coupled method ; thermal-mechanical coupling ; thermal damage ; marble strength ; direct and indirect methods ; correlations analysis ; artificial intelligence techniques ; performance indicators ; resonant column test ; torsional simple shear test ; damping ratio ; steady-state vibration ; free vibration decay ; bibliometric analysis ; pile foundation ; sustainable structure ; VOS viewer ; Web of Science ; red clay ; desiccation cracking mechanism ; digital image correlation technology ; strain ; displacement ; mineral carbonation ; comminution energy ; stress–strain relationship ; elastic properties ; radial distribution function ; crown deformation ; underground caverns ; parametric study ; multiple linear regression ; twin tunnels ; 3D numerical analysis ; surface settlement ; field measurement ; geotechnical and geological conditions ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 25
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Recent years have seen growing interest in equine lung and heart health, and advances in technology and a focus on equine welfare have driven this research. This Special Issue explores novel diagnostic and therapeutic approaches, including imaging techniques and lung function testing, immunological features, and immunomodulatory treatments for equine asthma and common racehorse respiratory issues. Moreover, it reports on novel echocardiography data of donkeys. This collection offers valuable insights into equine cardio-respiratory medicine.
    Keywords: equine asthma ; exercise-induced pulmonary hemorrhage ; racehorse respiratory medicine ; donkey cardiology ; bic Book Industry Communication::M Medicine
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  • 26
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on treating the associated comorbidities and complications of cerebral palsy. Increased prescription of technology means that we are treating some comorbidities of cerebral palsy earlier or even pre-emptively. Increased life expectancy, compared with 20 years ago, means that we are also seeing even later complications of cerebral palsy. However, increased access to intensive medical care at home, non-invasive ventilation, and total parenteral nutrition now exist. There is also greater engagement with the perspectives and expectations of parents/carers and children. As society begins to discuss mental health more openly, we are also starting to recognise the significant two-way associations between disability and mental health. Ethical consultation may be warranted when harm with treatment exceeds the benefit. As we prepare children with cerebral palsy for adulthood, there is more thought and discussion around issues such as pain, mental health, quality of life, independence, and participation. Researchers in the field of cerebral palsy have contributed original articles and reviews which help build our evidence base to guide shared decision making.
    Keywords: mental health ; anxiety ; depression ; cerebral palsy ; adolescence ; young adults ; young people ; adolescents ; unmet need ; health services ; physical therapy ; occupational therapy ; fracture ; bone fragility ; mortality ; epidemiology ; age-adjusted mortality rates ; death certificate ; medical education ; severe neurological impairment ; scoliosis ; shared decision-making ; respiratory ; hospitalisations ; antibiotics ; Indigenous ; inequities ; cell therapies ; stem cells ; comorbidities ; outcome measures ; clinical studies ; inflammation ; biomarker ; comorbidity ; scoping review ; co-design ; intervention ; participation ; involvement matrix ; public and patient involvement ; early intervention ; infant vocalisations ; infants ; single-subject research design ; CP ; infant ; stress ; parents ; fathers ; parent–infant interaction ; representations ; epilepsy ; children ; neuroimaging ; seizure outcome ; Sialorrhea ; submandibular duct relocation ; postoperative management ; ultrasound ; piecewise model ; muscle volume ; cross-sectional area ; GMFCS ; upper limb ; sensory function ; bimanual intensive functional therapy ; hand function ; associated impairment ; register ; low- and middle-income country ; hip displacement ; hip surveillance ; adductor-psoas release ; hip reconstruction ; guided growth ; salvage surgery ; disability ; emotion regulation ; atropine ; sialorrhea ; pediatric ; drooling ; sublingual ; developmental disorders ; neurodevelopmental disorders ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Autonomous vehicles are increasingly prevalent, navigating both structured urban roads and challenging offroad scenes. At the core of these vehicles lie the planning and control modules, which are crucial for demonstrating the intelligence inherent in an autonomous driving system. The planning module is responsible for devising an open-loop trajectory, taking into account a variety of environmental restrictions, task-related demands, and vehicle-kinematics-related constraints, while the control module ensures adherence to this trajectory in a closed-loop manner. This adherence is vital in a range of conditions, including diverse weather scenarios, different driving situations, and in response to potential disturbances such as mechanical failures or cyber threats. In certain contexts, these modules are collectively referred to as 'control', with the planning component considered an open-loop controller. This Special Issue focuses on the latest research trends in planning and control methods for autonomous driving. It comprises 11 papers that cover a broad spectrum of applications, including occlusion-aware motion planning in warehouses, control strategies for articulated vehicles, cooperative trajectory planning for autonomous forklifts, and tracking control for underwater vehicles in the face of disturbances and uncertainties. These contributions collectively underscore the diverse and evolving nature of autonomous vehicle technology.
    Keywords: autonomous vehicle ; infrared positioning ; occlusion-aware path planning ; numerical optimal control ; dynamic programming ; quadratic program ; underground intelligent vehicles ; path planning ; RRT* algorithm ; articulated vehicles ; unmanned driving ; spatial exploration ; hierarchical framework ; deep reinforcement learning ; intrinsic motivation ; obstacle avoidance ; data-driven control ; time delay neural network ; drift control ; autonomous driving ; nonlinear model predictive control ; brain–computer interface (BCI) ; steady-state visual evoked potential (SSVEP) ; electroencephalography (EEG) ; threatening pedestrians ; eye-tracking ; automated vehicle ; trajectory planning ; narrow corridor scene ; space discretization strategy ; articulated tracked vehicle ; adaptive model predictive control ; Hybrid A-star ; trajectory tracking ; kinematics ; improved A* algorithm ; GIS ; open-pit mine ; autonomous truck ; scheduling ; artificial bee colony algorithm ; autonomous forklift ; cooperative trajectory planning ; joint dispatching and planning ; Hybrid A* search algorithm ; artificial neural network ; autonomous underwater vehicle ; tube model predictive control ; path tracking ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TR Transport technology and trades
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    Springer Nature | Palgrave Macmillan
    Publication Date: 2024-04-11
    Description: In this open access book, Timothy Aylsworth and Clinton Castro draw on the deep well of Kantian ethics to argue that we have moral duties, both to ourselves and to others, to protect our autonomy from the threat posed by the problematic use of technology. The problematic use of technologies like smartphones threatens our autonomy in a variety of ways, and critics have only begun to appreciate the vast scope of this problem. In the last decade, we have seen a flurry of books making “self-help” arguments about how we could live happier, more fulfilling lives if we were less addicted to our phones. But none of these authors see this issue as one involving a moral duty to protect our autonomy.
    Keywords: Kantian ethics ; technology ; social media addiction ; artificial intelligence ; distraction ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTQ Ethics and moral philosophy ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYQ Artificial intelligence
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Energy crises and environmental pollution are two serious problems facing the development of human society. Photocatalysis is a promising environmentally friendly technology to address the above issues due to its low energy input and carbon footprint. In particular, graphitic carbon nitride, a typical organic–nonmetallic semiconductor photocatalyst, has become a research hotspot due to its unique properties; g-C3N4 is innoxious, inexpensive, easy to synthesize, has an appropriate energy band gap (2.7 eV), and demonstrates outstanding thermal stability and chemical stability. Nevertheless, some inherent scientific factors, such as its small surface area, low utilization of visible light, and fast recombination of electrons and holes, limit its applications in the field of photocatalysis. Among key modification methods, the construction of a heterojunction/homojunction between graphitic carbon nitride and other semiconductor photocatalysts with interleaved energy band positions is an effective approach to improve photocatalytic activity, attributed to the accelerated photon-generated carrier transfer rate. In particular, such S-scheme structures can simultaneously accelerate photon-generated carrier transfer rates and yield higher redox potentials. Therefore, there is an urgent need to design a neoteric g-C3N4-based photocatalytic system that can further promote the development of photocatalysis.
    Keywords: amine-based pharmaceutical ; graphene ; g-C3N4 ; nizatidine ; photocatalysts ; solar irradiation ; donor-acceptor ; graphitic carbon nitride ; PTCDA ; photocatalysis ; CO2 reduction ; g-C3N4@Cu0.5In0.5S ; S-scheme heterojunction ; hollow nanostructure ; photothermal effect ; FeTCPP@CNNS ; g-C3N4 nanosheets ; photocatalytic ; visible light ; SrTiO3 ; GO ; Rh active sites modification ; photocatalytic overall water splitting ; energy conversion ; pharmaceutical compounds ; catalyst ; wastewater ; treatment ; photothermal-assisted ; black g-C3N4 ; degradation ; cyano group defects ; semiconductors ; hydrogen peroxide ; photocatalyst ; Sb2S3 ; PANI ; ZnO ; reaction parameters ; structure design ; exfoliation ; quantum dots ; nanocomposite ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 30
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue compiles11 research papers published in the field of forestry and wood processing technology. In particular, this Special Issue highlights the research on timber saw, biomass and waste from resinous branches, forest by-products, log exploitation, the primary processing of round wood in timber with a band saw, the quality of exploited wood, and the role of the forest and forest ecosystem on the environment. Regarding wood science processes, this Special Issue presents works on cutting round wood in timber and veneers, technology 4.0, the manufacture of furniture and musical instruments, acoustical properties, wood biomass, including briquettes and pellets, thermochemical treatments of wood and pellets, finishing processes, and the restoration of cultural heritage objects using classical technologies and chemical materials. A lot of material waste was used to obtain better composites or chemical substances to obtain wood-based composites with better properties and low-level formaldehyde emission.
    Keywords: Wooden heritage object ; Forest biomass ; Wood products ; Forest environment ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 31
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint entails descriptions of novel issues and challenges for primary mental healthcare regarding both general and vulnerable populations on a global scale. It is intended for health professionals and all who are interested in mental health care at the primary level.
    Keywords: depression ; sense of coherence ; burnout ; COVID-19 ; nurses ; medication adherence ; mental health nurses ; tacit knowledge ; schizophrenia ; sensory processing sensitivity ; environmental sensitivity ; university students ; nursing ; scale ; somatization ; number of diseases ; coping strategies ; sex ; aggression ; alexithymia ; comprehensibility ; quality of life ; family caregivers ; students ; medical ; psychological problem ; undergraduate ; Saudi Arabia ; n/a ; prospect theory ; applied psychology ; health ; decision making ; behavior ; prevention ; multiple sclerosis ; Beck depression inventory ; anxiety ; fatigue ; mediation ; lawyers ; suicidal ideation ; occupational stress ; loneliness ; perceived stress ; mental health ; work overcommitment ; mental health care ; adolescence ; internalizing/externalizing problems ; social skills ; neurodevelopmental disorders ; filmmaking intervention ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint includes studies on diagnosing, evaluating and managing the pathologies diagnosed during pregnancy. The information provided in these pages is helpful for specialists in obstetrics and gynaecology but also for other medical specialities involved in treating pregnant women with associated pathologies. Studying the articles in the reprint could contribute to improving case management.
    Keywords: pregnancy ; fetus prenatal care ; high-risk ; pathology ; bic Book Industry Communication::M Medicine
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  • 33
    Publication Date: 2024-02-29
    Description: The monograph is devoted to the system analysis of approaches to the building of models of chemical-technological systems, on the basis of which a systematic concept of building of models and the issues of solving decision-making problems for managing the operating modes of technological objects is proposed. The problems of the development of mathematical models and the optimization of complex chemical-technological systems are investigated, using the example of technological objects of oil refining, in conditions of uncertainty caused by the lack of reliable quantitative information and the fuzziness of available information. The structure of the monograph consists of an introduction, the main part of four sections, a conclusion and a list of sources of information. In the main part of the work, the current state of the problems of mathematical modelling of technological objects of oil refining production is analyzed. Methods of mathematical modelling and decision-making in the management of technological objects according to environmental and economic criteria are chosen as the direction of research. Methods of building mathematical models of chemical-technological systems of oil refining in a fuzzy environment have been investigated and proposed, and models of the technological complex of the catalytic reforming unit have been developed. An approach to the creation of a package of models for system modelling of the technological complex of the catalytic reforming unit is described. An algorithm for the synthesis of models of a technological complex of oil refining based on fuzzy information is proposed. Expert assessments have been carried out to develop a mathematical description of the technological complex of the reforming unit, a method has been developed for carrying out expert procedures in a fuzzy environment. The formulations of decision-making problems for the control of the technological complex of the reforming unit are formulated and, based on the modification of various optimality principles, heuristic algorithms for their solution are developed. The properties of the developed algorithms for solving decision-making problems have been investigated and a method for their selection in solving specific production problems has been proposed. A mathematical formulation of the decision-making problem for optimizing the operating modes of the catalytic reforming unit in a fuzzy environment is obtained and the results of its solution based on the proposed fuzzy approach are presented. The structure is created and the main functional blocks of the computer decision support system based on the object models are described. The issues of software implementation of the developed models are considered and a description of the interface of the computer system for modelling the units of the reforming unit and decision support for optimizing their operation modes is given.
    Description: Published
    Keywords: Mathematical model ; Multi-criteria optimization ; Decision making ; Fuzzy information ; Technological object of oil refining ; Catalytic reforming unit ; System of modelling and decision-making support ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
    Language: English
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  • 34
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Three-dimensional printing is among the emerging technologies of our time. While it was previously primarily employed for rapid prototyping, this technology has entered a phase of accelerated production, especially for complicated or small objects. Most recently, novel 3D printing technologies have enabled objects with features at the micro- or even nano-scale to be fabricated. Meanwhile, well-known problems such as the waviness of fused deposition modeling (FDM)-printed parts, the missing long-term stability of some typical printing materials or the reduced mechanical properties of 3D-printed objects persist.This Special Issue focusses on all topics related to the 3D printing of micro-electro-mechanical systems (MEMS), such as novel or advanced features enabled by 3D printing compared to conventional technologies, but also the challenges that continue to exist regarding the application of 3D printing technologies for MEMS and new approaches to overcoming them.
    Keywords: 3D printing ; microelectromechanical systems (MEMS) ; microelectronics ; microfluidics ; microsensors ; microactuators ; inkjet printing ; zinc oxide ; heat treatment ; micro-heater ; semiconductor ; 2D printhead ; thermal inkjet ; thin-film resistors ; digital light processing ; projection micro-stereolithography ; micro beam ; fabrication ; additive manufacturing technology ; powder bed fusion ; surface geometrical parameters (SGP) ; lathe chuck jaws ; polymethylmethacrylate ; additive manufacturing ; fused deposition modeling ; passive ; pipeline ; pressure ; reactive impedance sensor ; structural health monitoring ; wireless ; DNA printing ; flow estimation ; MEMS ; ferrite materials ; magnetic thin films ; strontium ferrite nanomaterial ; relative permeability ; relative permittivity ; thermopneumatic ; micro actuator ; soft bellows actuator ; independent actuation ; polydimethylsiloxane ; standalone ; aerosol jet printing ; dielectric ; etching ; polyvinyl alcohol (PVA), polymers ; sacrificial material ; micro-electro-mechanical-system (MEMS) ; lithium niobate microring resonator ; silicon nitride waveguide ; photolithography assisted chemo-mechanical etching ; colorimetric device ; organophosphorus pesticide residues ; LCD mask photo-curing ; PolyJet 3D printing ; fidelity of 3D printing ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 35
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The aim of this Special Issue is to specify relevant principles of mathematics and mechanics in order to explore and understand biological problems. We summarize the most important parameters that influence human performance and that are related to the health sciences for all age groups, throughout their lives. We present papers that aim to introduce the latest research in the fields of health, quality-of-life improvement, and sport rehabilitation and that summarize their recommendations for best practice. The aim for this Special Issue is, therefore, to effectively combine and coordinate research and results in order to understand and improve human movement in medicine, sports, and at work.
    Keywords: tendinopathy ; Achilles tendon ; hyaluronic acid ; viscoelastic properties ; isometric contraction ; matrix metalloproteinase 3 ; interleukin-1beta ; fascia ; chronic low back pain ; myofascial release ; quality of life ; older adults ; oldest-old ; measurement invariance ; SHARE European Survey ; therapeutic exercises ; chronic neck pain ; scapular dyskinesia ; DOMS ; vibration ; post-exercise muscle damage ; physical exercise ; recovery ; women’s rugby ; anthropometry ; body composition ; adiposity ; somatotype ; lower-body strength ; accelerometry ; falls ; squat jump ; syndesmosis ; anterior inferior tibiofibular ligament ; high ankle sprain ; rotational instability ; posterior malleolus ; stabilization ; anatomic repair ; syndesmotic screw ; suture-button ; internal bracing ; treatment algorithm ; cardiac rehabilitation ; peripheral artery disease ; COVID-19 ; intermittent claudication ; review ; pressotherapy ; compression ; regeneration ; return-to-play ; rotator cuff repair ; shoulder injuries ; shoulder surgery ; shoulder assessment ; chronic obstructive pulmonary disease ; COPD ; acupuncture ; acupuncture therapy ; acupuncture treatment ; health-related quality of life ; anterior knee laxity ; stiffness ; general joint laxity ; genu recurvatum ; low back pain ; physical activity ; trunk alignment ; rasterstereographic system ; young males ; tissue flossing ; floss band ; vascular occlusion ; muscle strength ; muscle endurance ; warm-up ; TECAR therapy ; high-intensity laser therapy ; manual therapy ; muscle disorders ; hemophilia ; knee ; virtual reality exposure therapy ; joint pain ; physiotherapy ; daily physical function ; middle-aged and older adults ; CHARLS ; aging ; appendicular muscle mass ; inflammaging ; biomarkers ; adiponectin ; sarcopenia ; bic Book Industry Communication::M Medicine
    Language: English
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  • 36
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue brings together the latest advancements across various facets of viscous and viscoelastic fluid flows. Encompassing a spectrum of contributions, the topics span from innovative numerical methods and sophisticated mathematical modeling to cutting-edge experimental research. In addition to providing insights into the current state of research in these domains, the issue aims to foster a comprehensive understanding of the intricate dynamics and behaviors exhibited by viscous and viscoelastic fluids.
    Keywords: numerical methods ; analytical solutions ; boundary conditions ; computational rheology ; computational fluid dynamics ; mathematical models ; viscoelasticity ; complex viscous-viscoelastic flows ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 37
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The 3D analysis of human movement aims to objectively and quantitatively assess motor functions and alterations. It is a valuable method for sport scientists, coaches, and clinicians to evaluate sport performance, common movements, and alterations. The feasibility of 3D analysis is increasing because it can be adopted both in a laboratory setting or directly in the field, in static or dynamic conditions, and for physiological or pathological movements. This evaluation technique can be adopted for many people, including children, adolescents, adults, and older people, whether they are sedentary or athletes and whether they are healthy or motor-impaired people.
    Keywords: virtual reality ; augmented reality ; lifelogging ; mirror world ; health ; posture training ; feedback ; COVID-19 ; neck-shoulder-region ; shoulder protraction ; upper crossed syndrome ; posture weakness ; physical inactivity ; sedentary behavior ; soccer ; climbing ; exhaustion ; fatigue ; training ; machine learning ; sports ; gender ; data mining ; artificial intelligence ; posture ; reproducibility ; mobile app ; movement ; kinesiology ; sport performance ; inertial sensor ; inertial sensor device ; inertial measurement unit ; training load ; external load ; physical demand ; handstand ; postural control ; postural balance ; sEMG ; stabilometric assessment ; exercise ; Nordic walking ; walking ; 3D kinematics ; biomechanics ; gait analysis ; kyphosis ; spinal mouse ; photogrammetry ; postural evaluation ; bicycle ; cyclists ; saddle pressure ; perineal pressure ; urogenital system ; injury prevention ; cervical ROM ; elastic taping ; neck pain ; musculoskeletal health ; n/a ; bic Book Industry Communication::M Medicine
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  • 38
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the orthopedic surgical field, knee surgeries, including articular cartilage repair procedures, meniscus surgery, ligament reconstruction surgery, osteotomy surgery, and partial/total knee arthroplasty surgery, have made great advances over the last few decades. This Special Issue highlights and focuses on the surgical concepts and techniques, decision-making processes, perioperative management protocols, and clinical outcomes of the recent various advanced knee surgery procedures.
    Keywords: high tibial osteotomy ; TomoFix ; plate position ; anatomical conformity ; dual-energy CT ; Hounsfield unit ; bone mineral density ; volumetric phantomless BMD ; opportunistic CT ; orthopedic surgeon ; planning ; survey ; total knee arthroplasty ; unicompartmental knee arthroplasty ; anterior cruciate ligament ; reconstruction ; bone tunnel widening ; adjustable-loop device ; interference screw ; hamstring tendon ; autograft ; tibial component alignment ; radiographic references ; extramedullary system ; tranexamic acid ; clamping time ; transfusion ; estimated blood loss ; continuous cold flow therapy ; cryotherapy ; pain ; opioids consumption ; patient satisfaction ; bone marrow lesion ; knee ; meniscus ; root tear ; root repair ; femorotibial joint ; chondromalacia ; aging ; body mass index ; magnetic resonance imaging ; automated detection ; detection algorithm ; deep learning ; venous thromboembolism ; medial collateral ligament ; strain ; video extensometer ; medial opening-wedge high tibial osteotomy ; central sensitization ; patient-reported outcomes ; osteotomy site pain ; minimal clinically important difference ; human umbilical cord blood derived mesenchymal stem cells ; cartilage regeneration ; cartilage repair ; osteoarthritis treatment ; stem cell therapy ; Outerbridge ; degeneration ; spacer block ; intramedullary rod ; femorotibial congruence ; unicompartmental arthroplasty ; osteoarthritis ; cartilage ; stem cells ; umbilical cord blood ; femur fracture ; polyethylene insert ; osteoporosis ; multivariate logistic analysis ; atelocollagen ; microfracture ; ACIC ; bone marrow aspirate concentrate ; human umbilical cord blood-derived mesenchymal stem cells ; knee osteoarthritis ; loosening ; arthroplasty ; machine learning ; transfer learning ; review ; prosthesis ; meniscus root ; medial meniscus posterior root ; medial meniscus posterior root tear ; meniscus root repair ; transtibial pull-out repair ; bone tunnel enlargement ; anterior cruciate ligament reconstruction ; landmark ; lateral tibial spine ; anatomy ; bic Book Industry Communication::M Medicine
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  • 39
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Over the years, digestive endoscopy has gone through a revolution. With different technological improvements, its diagnostic role is indeed becoming more and more sophisticated and is even moving closer to pathological evaluation. Above all, its therapeutic purpose is to date the first line of treatment for several gastrointestinal diseases. Importantly, the role of digestive endoscopy is also crossing over the mere concept of the GI tract and digestive diseases and will probably find a place in a more holistic concept of health. In this Special Issue, several emerging techniques are addressed, highlighting how endoscopy is emerging as a minimally invasive treatment procedure for several gastrointestinal diseases and post-surgical complications. However, crucial to this is the safety of all endoscopic processes, starting from endoscopic suites to the management of intra- and post-procedural complications.
    Keywords: interventional endoscopy, ERCP, cholangioscopy, biliopancreatic endoscopy, CH-EUS, radiofrequency ablation, necrosectomy, locoregional treatment, bariatric endoscopy, artificial intelligence ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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  • 40
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: A high demand for metals (cobalt, copper, gold, lithium, nickel, tin, vanadium, etc.) has been recorded for the past several decades, and this demand is expected to increase even further in the coming decades as the world moves to low-carbon technologies based on renewable energy sources (RESs) and electric vehicles (EVs) and away from the heavy use of fossil fuels. To meet the high forecasted demand, unconventional sources of metals such as low-grade complex ores, seafloor massive sulfides (SMSs), and wastes (e.g., tailings, metallurgical residues, and electronic wastes (e-wastes)) have become very important sources of metals; moreover, these metals should be extracted in a sustainable manner without negatively impacting the environment. This Special Issue focused on recent advances in the sustainable production of metals from the above-mentioned unconventional sources.This reprint is a compilation of a Special Issue of Minerals, “Sustainable Production of Metals for Low-Carbon Technologies”, where 13 papers contributed by experts in the area were published. Papers published in this Reprint cover a wide range of topics, including mineral processing (gravity concentration, magnetic separation, and flotation), hydrometallurgical techniques (leaching, solvent extraction, and cementation) to extract minerals/metals from primary and secondary resources. All the papers are of high scientific value and will be of great interest to readers of Minerals.
    Keywords: flotation circuit ; gold ore ; diagnosis ; optimization ; mass balance ; process simulation ; printed circuit boards ; heat treatment ; strength ; liberation ; Cu recovery ; physical separation ; ferronickel slag ; sulfuric acid leaching ; light magnesium oxide ; rare earth elements ; magnetic separation ; upgradation ; Khalzan Buregtei deposit ; NiMH batteries ; rare earth metals ; leaching ; solvent extraction ; precipitation ; gold ; cementation ; galvanic interaction ; aluminum ; activated carbon ; kinetics ; ammonium thiosulfate solution ; mass transfer ; fluorine ; occurrence ; removal ; gravity-flotation separation ; lignite ; lead ; zinc ; Al metal powder ; zinc plant leach residues ; flotation ; copper sulfides ; tailings ; carrier flotation ; flocculation ; oil agglomeration ; complex sulfide ores ; sphalerite ; anglesite ; extraction ; lithium ion battery ; recycling ; carbothermic reduction ; graphite ; porphyry copper deposits ; chalcopyrite ; pyrite ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TT Other technologies and applied sciences::TTU Mining technology and engineering
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  • 41
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Modern medical imaging systems provide information about the patient's health condition. Their precision, resolution and sensitivity are increasing, and new possibilities of differentiating the condition of tissue are constantly appearing. These advances are also taking place in musculoskeletal imaging. Increasingly accurate imaging in various modalities allows us to discover new relationships between the image and the diagnosis. It is therefore important to use all this information to best serve the patient. That is why research related to the analysis of medical images is so important, because it allows us to indicate what is invisible to the naked eye or to quantify what has so far been measured by humans or subject to discretionary assessment. This collection includes 25 works related to the analysis of images created during diagnostics of the musculoskeletal system using various modalities—from X-ray and fluoroscopy to conventional or spectral computed tomography, magnetic resonance imaging, ultrasound, elastography, PET/CT and systems for analyzing patient mechanics. Research was carried out related to the detection of various conditions, parameterization of clinical and population phenomena, and detection of image–clinical condition relationships. Despite the current popularity of machine learning techniques, the collection is dominated by classic engineering methods related to image processing. Several works use textural analysis, which has not been appreciated so far, which is particularly related to the imaging of the structure, especially of bones.
    Keywords: bone imaging, musculoskeletal imaging, image processing, image analysis, segmentation, textural analysis, machine learning ; bic Book Industry Communication::M Medicine
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  • 42
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Aluminum alloys and aluminum matrix composite materials have become the first choice to replace steel materials due to their high specific strength. The penetration rate of light alloys in new energy vehicles, the aerospace industry, and the rapid rail transit industry is increasing quickly. The reduction in energy consumption resulting from structural weight reduction is the key element for sustainable development. For example, every 100 kg reduction in car mass can save 0.6 L of fuel per 100 kilometers and reduce the emission of 800–900 g of carbon dioxide. For every 10% reduction in the weight of new energy vehicles, their range can be increased by 5.5% (for every 10 kg reduction in the weight of pure electric vehicles, their range can be increased by 2.5 km). The comprehensive proportion of aluminum alloys in automobiles will reach about 26% by 2040. The vigorous development of the automotive manufacturing industry has provided a huge application scenario for aluminum alloy profiles, aluminum alloy castings, and forgings. In addition, the use of aluminum in aerospace and high-speed rail is even more widely recognized. This Special Issue summarizes research on and the application of aluminum alloys of typical composition, including AlZnMgCu, AlCu, AlMn, and even Ti-aluminum alloys.
    Keywords: AlZnMgCu alloy ; AlMgSi alloy ; AlSiMgCu alloy ; AlCu alloy ; Deformation ; Modeling ; Properties ; Microstructure ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 43
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Pain biomarkers are biological indicators or measurable characteristics that can provide information about the presence, severity, or underlying mechanisms of pain. They are valuable for several reasons: Diagnosis and differential diagnosis: Biomarkers can help in the diagnosis of various pain conditions and differentiate between different types of pain, such as neuropathic, inflammatory, or nociceptive pain. This can lead to more accurate and timely diagnoses, which in turn can improve patient care. Monitoring treatment efficacy: Pain biomarkers can be used to track how well treatments are working for individuals suffering from chronic pain conditions. This allows healthcare providers to make informed decisions about adjusting treatment plans, optimizing pain management, and avoiding unnecessary or ineffective interventions. Drug development and testing: Biomarkers play a crucial role in the development of new pain medications and therapies. They can help researchers identify potential drug targets, screen compounds for their pain-relieving properties, and assess the safety and efficacy of experimental treatments in clinical trials. Personalized medicine: Pain biomarkers may, in a future, contribute to treatments, tailored to an individual's unique genetic and biological disposition. Reducing opioid misuse: By using biomarkers to assess pain and treatment responses, healthcare providers can make more informed decisions about opioid prescriptions, potentially reducing the overuse and abuse of these medications.
    Keywords: analgesia ; biomarker ; CSF ; cytokine ; inflammation ; neuropathy ; neurotransmitter ; pain ; QoL ; sensitization ; sensory ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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  • 44
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The fatigue of metallic materials stands as a pivotal challenge in engineering applications. Exploring the fatigue damage mechanism and fatigue life prediction of metallic materials is of paramount importance. This reprint includes articles that explore relevant topics, and they are intended for academic researchers, engineers, and students seeking a comprehensive understanding of the recent advancements in this field.
    Keywords: 7075 aluminum alloy ; outdoor exposure ; actual marine atmosphere ; pre-corrosion ; fatigue ; fretting fatigue ; digital image correlation ; relative slip ; tangential contact stiffness ; planetary transmission ; hierarchical analysis ; finite element method ; reliability modeling ; fatigue test ; nickel-based superalloy ; non-unified constitutive models ; creep-fatigue ; cyclic softening ; stress relaxation ; 2D-EBSD mapping ; intragranular misorientation ; KAM and GROD ; isotropic linear evolution ; mesoscopic plastic strain ; 3D polycrystalline plasticity model ; nickel-based alloy GH4169 ; complex stress state ; biaxial fatigue ; fatigue crack behavior ; phase field methods ; fatigue fracture ; performance improvement strategies ; rails ; rail steel ; reutilization ; fatigue life ; rail reliability ; crack ; geometric factor ; support vector regression ; pilot plant ; shape optimization ; flow guide disk ; vent hole ; design optimization ; fatigue crack initiation ; short crack ; Neuber’s rule ; strain energy density (SED) ; finite element analysis (FEA) ; TRIP steel ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 45
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on the comprehensive understanding and novel treatments in the realm of cornea and ocular surface diseases. Ranging from the relatively benign manifestations of keratoconjunctivitis sicca to more critical conditions such as corneal ulcers, ocular surface diseases pose a considerable challenge in clinical ophthalmology. Such conditions can severely compromise the transparency of the cornea, often necessitating interventions such as keratoplasty. A significant emphasis of this edition is on the paramount importance of pre-surgical optimization. A successful keratoplasty is often predicated on the health of the ocular surface. Through a series of insightful articles, the importance of enhancing tear function, rehabilitating the normal lid anatomy, and ensuring a robust limbal stem cell supply is elucidated. Properly addressing these factors has a direct bearing on the success rate of the subsequent surgical intervention. Another highlight of this Special Issue is the presentation of cutting-edge treatments. Researchers from around the globe share their findings, detailing advancements in both surgical and non-surgical treatments. These range from innovative surgical techniques and tools to groundbreaking pharmaceutical agents that hold promise in managing and possibly reversing some of these conditions. In summary, this Special Issue serves as a repository of the latest knowledge in the management of cornea and ocular surface diseases, aimed at both the seasoned ophthalmologist and budding researchers in the field.
    Keywords: cornea ; ocular surface disease ; dry eye ; corneal ulcer ; keratoplasty ; bic Book Industry Communication::M Medicine
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  • 46
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions, and liposomes, have been extensively studied to improve drug delivery through different administration routes. The main advantages linked to these systems are the ability to protect, transport, and control the release of lipophilic and hydrophilic molecules (either small molecular weight or macromolecules); the use of generally recognized as safe (GRAS) excipients that minimize the toxicity of the formulations; and the possibility to modulate pharmacokinetics and enable the site-specific delivery of encapsulated payloads. In addition, the versatility of lipid-based nanosystems has been further demonstrated through the delivery of vaccines, protection of cosmetic actives, or improvement in the moisturizing properties of cosmetic formulations. Currently, lipid-based nanosystems are well established, and there are already different commercially approved formulations for different human disorders. This success has actually paved the way to diversifying the pipeline of development, upon addressing unmet medical needs for several indications, such as cancer; neurological disorders; and autoimmune, genetic, and infectious diseases. This Special Issue aims to update readers on the latest research on lipid-based nanosystems, both at the preclinical and clinical levels.
    Keywords: design of experiment ; porcine mucous membrane ; ophthalmic tissues ; permeation ; nanostructured lipid carriers ; gentiopicroside ; phospholipid complex ; self-nanoemulsion drug delivery system ; oral bioavailability ; pharmacokinetics ; antioxidants ; marine bio-waste ; bioactive compounds ; neurodegenerative diseases ; NLC ; solid lipid nanoparticles ; SLN ; intranasal administration ; nose-to-brain ; exosome ; drug loading ; exosomal delivery ; large-scale production ; lipid nanoparticles ; mucoadhesion ; ocular bioavailability ; surface modification ; liposomes ; baricitinib ; JAK-inhibitor ; transepidermal delivery ; skin permeation ; lipid NPs ; breast cancer ; siRNA delivery ; gene silencing ; personalized therapy ; bimatoprost ; central composite design ; glaucoma ; HET-CAM test ; solid lipid nanoparticles (SLNs) ; perillyl acid ; biodistribution ; empty lipid nanoparticles ; reactogenicity ; xenobiotics ; ionizable lipids ; isoniazid ; in vivo pharmacokinetics ; drug release profile ; histopathological toxicity ; mannosylation ; nanocarriers ; Chagas disease ; Trypanosoma cruzi ; in vivo assays ; quality by design ; plumbagin ; diabetes ; in vitro ; niosomes ; levosulpiride ; antidepressant ; acute toxicity ; in vivo imaging ; bioavailability ; cisplatin ; co-encapsulation ; mifepristone ; synergism ; gefitinib ; lipid ; surfactant ; stability ; breast cancer cell ; MTT assay ; anticancer ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 47
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The 3rd International Conference on Advances in Mechanical Engineering 2023 (ICAME-23) was organized on 24th August 2023 by the Department of Mechanical Engineering, Capital University of Science and Technology (CUST). All the articles are single-blindfold reviewed. The acceptance rate of the conference was 65%. ICAME is held annually and welcame high-quality theoretical and empirical original research papers, case studies, and review papers from researchers, academicians, professionals, practitioners, and students worldwide. ICAME-23 accepted research papers in the discipline of: Experimental and Computational Fluid Dynamics; Thermodynamics and heat transfer analysis; Machine and Mechanisms; Design and Solid Mechanics; Manufacturing, Production and Industrial Engineering; Engineering and Technology Management; Renewable Energy and Environmental Engineering; Bioengineering; Materials and Failure Analysis; Other Related Fields. The ICAME-23 conference provided a platform for the national and international speakers/participants to present their state-of-the-art research work to diverse audiences from academia and industry. The conference proceedings are published in the Engineering Proceeding of MDPI, Switzerland. All the articles are individually indexed and are citable via Digital Object Identification (DOI).
    Keywords: Engineering ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials
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  • 48
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Fault detection and state estimation are essential tasks for ensuring the reliability, safety and performance of automatic control systems. They play a critical role in detecting and isolating faults quickly and accurately, enabling timely corrective action and preventing system failures. The field of fault detection and state estimation has seen significant advances in recent years, driven by the integration of advanced methodologies with cutting-edge technologies, in particular artificial intelligence and deep learning. These techniques have demonstrated remarkable capabilities in fault diagnosis, state estimation and fault-tolerant control, especially in complex multi-sensor systems. This Special Issue highlights and discusses the design and application of fault detection algorithms, the design and application of state estimation methods, the design and application of machine learning algorithms, the analysis of automatic control system characteristics, and the design and application of intelligent control systems. Nevertheless, many challenges remain and require attention, including scalability, computational efficiency, online implementation, fault isolation, fault recovery and fault-tolerant control. Additional research efforts are therefore essential to advance both the theory and practice of this critical task.
    Keywords: Intelligent Control ; Intelligent Modeling ; Computational Intelligence ; Artificial Intelligence ; State Estimation ; Fault Detection ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 49
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This textbook “Applied Mathematics in Ferroelectricity and Piezoelectricity” was authored to provide the reader solid mathematical background for studying “ferroelectricity and piezoelectricity”, as a supplemental reference to my three course books; “Ferroelectric Devices 2nd Edition (2010)”, “Micromechatronics 2nd Edition (2019)”, and “FEM and Micromechatronics with ATILA Software (2008)”, all published from CRC Press. “Physics” prefers “simplicity”; converting a complicated phenomenon expressed by a function.
    Keywords: ferroelectrics ; piezoelectricity ; phenomenology ; applied mathematics ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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  • 50
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: As people become more environmentally aware and recycle , the reuse of waste materials and the application of sustainable techniques in the construction field have become popular. This reprint collates new green and sustainable infrastructure construction materials, including cement and asphalt concrete, biomass, and composite infrastructure materials. This collection should be used as a guidance for the future field application of new techniques for the improved environmental sustainability of infrastructure constructions.
    Keywords: sustainable infrastructure materials ; green cement concrete ; asphalt and mixtures ; material and structure of road engineering ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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  • 51
    Publication Date: 2024-02-27
    Description: Collective monograph contains the results of scientific research devoted to the search for effective scientific and applied solutions for the operation of logistics systems. The problems posed are considered through the prism of technological and economic views, which contributes to the formation of the practical significance of the results of systematic research, which are highlighted in the monograph. Section 1 examines which multimodal logistics solutions in emergency situations and transport security threats have proven effective during the war in Ukraine. The given transport and logistics solutions can be considered promising from the point of view of integrative capabilities at a new level of transport competitiveness and defense capability. In Section 2, practical measures are proposed to improve logistics solutions in transport and customs services in international traffic to ensure the efficiency and reliability of the national economy. In Section 3, the impact of information provision of truck crews performing transport tasks on road traffic is investigated, and an effective scheme for information support of cargo delivery conditions is developed. In Section 4, solutions are proposed for evaluating the effectiveness of the ecological system project using the "discounted payback period" criterion, which takes into account transformational changes in its life cycle model. In Section 5, solutions are proposed that allow for a reasonable selection of the composition of consumers and partners for each enterprise, taking into account their characteristics and strategies of information interaction, ensuring an increase in the efficiency of the "consumer - enterprise - partner" system based on the criterion of profit maximization. The monograph is intended for practitioners who are engaged in the search and implementation of effective technological solutions in the field of logistics, in particular according to economic criteria, and scientists who investigate applied problems of the functioning of logistics systems. The monograph can also be useful to postgraduate and master's students of universities in the relevant educational and scientific profile.
    Description: Published
    Keywords: Transportation events ; Humanitarian supply chains ; Intermodal transportation ; Traffic safety management information systems ; Customs service ; Logistics risks ; Containerized transportation ; Cargo delivery ; Logistics chain of flow delays ; Ecological system ; Information interaction ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 52
    Publication Date: 2024-01-08
    Description: This reprint, entitled “Management of Acute and Chronic Complications of Lysosomal Storage Diseases in Children and Adults: Current Practice and Future Opportunities”, covers broad aspects of this group of rare diseases. The first theme includes articles on the management of pain, corneal clouding, gastrointestinal and airway diseases in Mucopolysaccharidoses and Mucolipidoses, and the evaluation of dysphonia in Pompe disease. Additionally, attention deficit and ADHD and the management of atherosclerosis in Fabry disease are considered here. The second theme includes diagnostic conundrums in lysosomal storage diseases, e.g., the prenatal diagnosis of Gaucher disease during pregnancy, the diagnosis of secondary hyperparathyroidism in Mucolipidoses, and the application of the new biomarker “plasma neurofilament light” in Niemann Pick C disease, as well as the correlation of enzyme activity with molecular diagnosis in Pompe disease. The articles in the third theme describe the impact of therapies on clinical outcomes. For example, a systematic review of the impact of enzyme replacement therapy on late-onset Pompe disease and trehalose use on Niemann Pick A and B is included. The remaining articles describe the NHS processes for overcoming challenges resulting from the COVID-19 pandemic and the differences in the transition from paediatric to adult services between different countries.
    Keywords: Mucopolysaccharidosis ; corneal clouding ; penetrating keratoplasty ; deep anterior lamellar keratoplasty ; mucopolysaccharidoses ; airway ; obstruction ; management ; Fabry disease ; attention ; Attention Deficit/Hyperactivity ; cognition ; late-onset Pompe disease ; gastrointestinal ; smooth muscles ; PROMIS–GI symptom scales ; GAAKO mice ; glycogen storage disorder ; translational research ; patient-reported outcomes measures ; mucopolysaccharidosis ; MPS ; disease manifestations ; symptoms ; morbidity ; spine disease ; anaesthesia ; perioperative complications ; surgery ; pompe disease ; speech ; voice ; dysphonia ; acoustic ; auditory-perceptual ; GRBAS ; respiratory ; Pompe disease ; gene panel sequencing ; alpha-glucosidase ; GAA ; dried-blood spots ; fabry disease ; neuropathic pain ; depression ; Fabry ; atherosclerosis ; ischaemia ; perfusion ; angina ; Sanfilippo syndrome ; mortality ; Niemann–Pick C ; neurofilament light ; biomarkers ; neurological disease ; glycogen storage disease type II ; enzyme replacement therapy ; COVID-19 ; inherited metabolic disorders ; rare autoinflammatory diseases ; health care providers ; Gaucher disease ; NIHF ; perinatal-lethal Gaucher disease ; PLGD ; ichthyosis ; GBA gene ; airway management ; radiology ; hyoid bone ; chin ; intubation ; intratracheal ; lysosomal storage disease (LSD) ; Niemann–Pick type A ; Niemann–Pick type B ; acid sphingomyelinase ; sphingolipid deposition ; trehalose ; mucolipidosis type II ; ML II ; I-cell disease ; hyperparathyroidism ; mucolipidosis ; ML ; MLII ; transition service ; adult metabolic medicine ; collaboration ; challenges ; inherited metabolic diseases ; healthcare systems ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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  • 53
    Publication Date: 2024-03-14
    Description: This open access book is dedicated to exploring methods and charting the course for enhancing engineering education in and beyond 2023. It delves into the idea that education, coupled with social connections, is indispensable for a more profound comprehension of the world and the creation of an improved quality of life. The book serves as a conduit for incorporating complex problem-solving into engineering education across various formats. It offers a structured approach for tackling complex issues, comparing an array of techniques for managing complexity within the realm of engineering education. Moreover, the book scrutinizes several complex case studies derived from the United Nation's Sustainable Development Goals. Additionally, it explores intricate problem-solving and curriculum change case studies specific to engineering education from Harvard University, the University of Technology Sydney, and Aalborg University.
    Keywords: System Thinking in Education ; Engineering Education ; Complexity in Engineering Education ; Complex Problem Solving in Engineering Education ; Problem Solving in Education ; Design Engineering in Education ; Mega Projects in Engineering Education ; Human Challenges in Education ; Sustainable Development Goals and Education ; Engineering Education Curricula ; Social Challenges and Engineering ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::J Society & social sciences::JN Education ; bic Book Industry Communication::J Society & social sciences::JH Sociology & anthropology::JHB Sociology ; bic Book Industry Communication::J Society & social sciences::JN Education::JNT Teaching skills & techniques ; bic Book Industry Communication::J Society & social sciences::JN Education::JNK Organization & management of education::JNKC Curriculum planning & development
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  • 54
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    Brill
    Publication Date: 2024-04-04
    Description: This volume of collected studies takes stock of most recent developments in Egyptology and the Digital Humanities, considering future directions for the application of new technologies in Egyptology. The book presents the results of an international conference held in 2019 at Indiana University – Bloomington, in which Egyptologists and digital humanists with interest in Egyptology gathered in 2019 to present current projects in 3D modeling, virtual and augmented reality, game technology, digital pedagogy, database projects, computational and corpus linguistics and E-publications. Those projects, along with a selection of others that were not presented in Bloomington, are now described and discussed in this volume.
    Keywords: 3D modelling ; 3D technology ; Archaeology ; Art History ; Computational Analysis ; Digital Humanities ; Digitization ; Egyptology ; Linguistics ; Philology ; Photogrammetry ; Virtual Heritage ; Virtual Reality ; thema EDItEUR::N History and Archaeology::NK Archaeology::NKD Archaeology by period / region ; thema EDItEUR::1 Place qualifiers::1Q Other geographical groupings: Oceans and seas, historical, political etc::1QB Historical states, empires, territories and regions::1QBA Ancient World::1QBAE Ancient Egypt ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::3 Time period qualifiers::3C BCE period – Protohistory
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  • 55
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    Brill
    Publication Date: 2024-04-04
    Description: Translating Technology in Africa brings together authors from different disciplines who engage with Science and Technology Studies (STS) to stimulate curiosity about the diversity of sociotechnical assemblages on the African continent. The contributions provide detailed praxeographic examinations of technologies at work in postcolonial contexts. The series of 5 volumes aims to catalyse the development of a field of research that is still in its infancy in Africa and promises to offer novel insights into past, present, and future challenges and opportunities facing the continent. The first volume, on "Metrics", explores practices of quantification and digitisation. The chapters examine how numbers are aggregated and how the resulting metrics shape new realities. Contributors include Kevin. P. Donovan, Véra Ehrenstein, Jonathan Klaaren, Emma Park, Helen Robertson, René Umlauf and Helen Verran
    Keywords: access to information ; algorithmic decision-making ; carbon ; concept possession ; credit ; digital infrastructure ; digital labour ; Gabon ; Kenya ; machine-learning models ; measurement ; Nigeria ; platforms ; privacy ; quantification ; remote sensing ; South Africa ; tropical forests ; Uganda ; Yorùbá ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::P Mathematics and Science::PB Mathematics ; thema EDItEUR::P Mathematics and Science::PD Science: general issues::PDR Impact of science and technology on society ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::1 Place qualifiers::1H Africa
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  • 56
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Molecular toxicology is a field that investigates the interactions between chemical or biological molecules and organisms at the molecular level. In this Special Issue, we focus on the toxic effects and mechanisms of action of chemical and biological molecules, will be of great interest of readers in molecular toxicology and applied pharmacology.
    Keywords: smoking ; inflammatory ; cytokine ; human serum ; GO ; PRRSV ; FT-SPR ; sensitization ; NNK ; nicotine ; cytotoxicity ; genotoxicity ; cytochrome P450 2A13 ; Aspergillus flavus ; aflatoxins B1 ; carcinogen ; Surface-Enhanced Raman Scattering ; colloidal Au nanoparticles ; portable Raman spectrometer ; Euphorbia semen ; Euphorbia factors ; transcriptome ; RNA sequencing ; bioinformatics ; gene structure ; neuroblast differentiation-associated protein AHNAK ; hepatocellular carcinoma (HCC) ; insulin-like growth factor 1 receptor (IGF-1R) ; interactome ; field cancerization ; 8–17 DNAzyme ; gene silencing ; catalysis ; antisense ; chemical modifications ; 6-cyclohexyl methyl-β-D-maltoside ; transduction efficiency ; conditionally replicative adenovirus ; lethal effect ; gene therapy ; PBDE ; immunotoxicity ; macrophage ; reactive oxygen species ; apoptosis ; immune function ; breast cancer ; signature ; aging ; cancer ; nomogram ; immunotherapy ; tumor mutation burden ; doxorubicin ; Toll-like receptor 4 ; cardiotoxicity ; heart ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology::MMGT Medical toxicology
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  • 57
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The reprint, titled ”Sustainable Biopolymer-Based Composites: Processing, Characterization, and Application”, is composed of 32 scientific works of scholars that contributed their own expertise passion, and science to expand the boundaries of knowledge by addressing new challenges. The topic of new biopolymer-based composite materials is addressed from several aspects, from the development to characterization and application, in several fields of scientific interest.
    Keywords: biopolymer-treated soil ; Xanthan Gum ; Guar Gum ; soil strength ; durability ; cyclic wetting-drying ; biodegradability ; carbon nanotubes ; graphene ; life cycle analysis ; nanocomposites ; packaging ; remediation ; starch ; aging ; coarse wool fibre ; hybrid composites ; natural rubber ; PALF ; sisal fibre ; mulch films ; biopolymers ; SDGs ; plastic pollution ; polymers ; microfluidics ; lab-on-chip ; biomedical engineering ; drug carrier ; artificial cell ; 3D bioprinting ; hydrogel films ; gelatin ; antimicrobial activity ; food packaging ; TGA ; biocomposites ; renewable sources ; wood waste ; waste valorization ; primerless-wet bonding ; resin adhesive system ; hybrid layer ; tensile bond strength ; micro-seal ; luting resin ; dental prosthesis ; fixed prosthodontics ; bioplastics ; conventional polymers ; renewable resources ; LCA ; fish collagen ; fish industry waste ; collagen extraction ; nano collagen ; sustainability ; poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) ; cellulose nanofiber ; bionanocomposite ; melt-extrusion processing ; optimization ; response surface methodology ; acrylonitrile butadiene rubber ; fish scale ; bis(triethoxysilylpropyl)tetrasulfide ; composite ; compatibilizer ; collagen biopolymer ; unicornfish bone ; acid extraction ; characterization ; biocompatible ; biodegradable ; scaffolds ; tissue engineering ; lignin biopolymer ; erosion ; triaxial test ; wetting and drying cycles ; silt ; green macroalga ; red sea ; Chaetomorpha linum ; cellulose nanocrystals ; green silver nanoparticles ; bio-nanocomposite films ; optical properties ; Torenia fournieri ; zinc oxide nanoparticle ; smart packaging sensors ; wound healing ; biodegradable plastic ; circular economy ; pineapple ; tensile strength ; silver nanoparticles ; green synthesis ; Piper betle L. leaf ; pig lining leather ; antibacterial activity ; antifungal activity ; polylactic acid (PLA) ; spent coffee grounds (SCG) ; rheological properties ; mechanical properties ; chitosan ; nanofiber ; preparation ; applications ; wound dressing ; acetylation ; flour ; physicochemical properties ; modification ; wound dressings ; hydrogel ; honey ; natural polymer ; synthetic polymer ; PLA ; biodegradation ; sports equipment manufacturing ; arrowroot starch ; heat-moisture treatment ; octenylsuccinilation ; dual-modification ; functional properties ; glabridin ; 3-O-Ethyl-L-ascorbic acid ; tranexamic acid ; microneedles ; pigmentation ; multifunctional drug ; hydrophilic bioplastics ; gum Arabic ; polyvinyl alcohol ; casting of poly-(methyl methacrylate) ; dehydration ; phosphorus pentoxide ; peeling ; microbial biodegradation ; green composites ; stem fiber ; crystallinity ; thermal behavior ; reinforcement material ; pineapple leaf fiber ; flax ; poly(butylene succinate) ; unidirectional composites ; microstructure ; sustainable materials ; epoxy resin ; Schiff base ; epoxidized soybean oil ; epoxy vitrimer ; reprocessability ; recyclability ; agroindustrial wastes ; biomaterials ; cellulose ; lignocellulosic biomass ; polylactic acid ; coir fiber ; bamboo leaf fiber ; annealing ; biocomposite ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering
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  • 58
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, we have gathered high-level research papers from all over the world. We would like to thank all researchers for their commitment to the field. From diagnostic ultrasound of different fetal conditions to advanced cardiovascular imaging leading to fetal MRI and from serum markers and biomarkers in maternal and fetal conditions to new modalities in fetal therapy, this Special Issue covers a large scale view of the present spectrum of modern perinatal medicine. Again, a warm thank you to all contributors.
    Keywords: fetal echocardiography ; fetal abnormalities ; fetal therapy ; genetic testing, prenatal medicine ; bic Book Industry Communication::M Medicine
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  • 59
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Innovation in chemical plant design is driving improvements in efficiency, safety, and environmental sustainability. This progress is influenced by factors such as safety standards, environmental regulations, market dynamics, and technological advancements. Innovations encompass process intensification, modular design, automation, data analytics, and sustainability solutions, addressing modern challenges. These innovations have diverse applications, spanning drug delivery systems, textile technologies, spray drying, extraction, and active packaging. Notably, supercritical fluid-assisted production of liposomes in pharmaceuticals promises improved therapeutic outcomes through meticulous optimization and sustainability. The textile industry sees advancements in natural dyeing and antibacterial properties, while spray-drying and extraction processes enhance product development and sustainability. Integration of remote sensing and microelectronics aids land surface temperature understanding for applications like agriculture and climate change studies. Convolutional Neural Networks benefit material science, facilitating material identification for energy storage and lubrication applications. Techno-economics for gas-to-liquid processes in natural gas are vital for energy and environmental sustainability. The industry's ongoing evolution prioritizes safety, sustainability, and efficiency, relying on innovative approaches and technologies to create safer, more sustainable, and economically viable chemical processes with reduced environmental impact, contributing to a prosperous and sustainable future.
    Keywords: supercritical fluids ; mass spectroscopy ; ultra-high-pressure liquid chromatography ; cytotoxic compound ; phytosterol ; stigmasterol ; supercritical antisolvent ; micronization ; coprecipitation ; biomedical field ; drug delivery ; Wendita calysina ; burrito ; supercritical fluid extraction ; fractional separation ; D-carvone ; anticancer ; antimicrobial ; liposomes ; carbon dioxide ; high pressure systems ; antibiotics ; lutein ; Weibull model ; techno-economic analysis ; GtL ; Fischer–Tropsch ; ASPEN–Python ; Monte Carlo simulation ; pharmaceutical applications ; biomedical ; graphite ; classification ; transfer learning ; focal loss ; convolution neural network ; supercritical fluid impregnation ; electrospinning ; solvent casting ; antioxidant packaging ; materials optimization ; Landsat 8 LST product ; MODIS ; spatiotemporal fusion ; validation ; electroless nickel-electroless palladium-immersion gold ; Sn-58Bi ; ball grid array ; intermetallic compound ; deep eutectic solvent ; sustainable chemistry ; antioxidant activity ; Euterpe edulis ; experimental design ; spray drying ; agglomeration ; multiple nozzles ; single nozzle location ; air-atmospheric plasma ; mordant ; natural dye ; cotton ; antibacterial activity ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TD Industrial chemistry and manufacturing technologies::TDC Industrial chemistry and chemical engineering
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  • 60
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The topics covered in this Special Issue range from breastfeeding and early-life nutrition to effects on microbiota, infection, allergy, asthma, and the mechanisms of immunomodulation via (the early introduction of) nutrition on infections and the development of (food) allergies.
    Keywords: diet ; pregnancy ; cord blood ; fatty acids ; n-3 PUFAs ; n-6 PUFAs ; arachidonic acid ; phospholipids ; atopic eczema ; NICE birth cohort ; multi-allergen ; early introduction ; food allergy ; safety ; efficacy ; prevention ; allergic sensitization ; foetal immune ontogeny ; gene/environment interactions ; asthma ; eczema ; maternal diet ; PUFAs ; vitamin D ; Mediterranean diet ; microbiome ; breastfeeding ; functional gastrointestinal disorder ; partial hydrolysate ; peptide ; protein ; infancy ; childhood ; immune development ; probiotic ; microbiota ; allergy ; atopic dermatitis ; breastmilk ; house dust mite ; Der p 1 ; Asthma ; total IgE ; atopy ; sensitization ; oral tolerance ; early food introduction ; milk protein ; cow’s milk allergy (CMA) ; maternal atopy ; epigenetics ; pediatric asthma ; cohort study ; immune complex ; trained immunity ; RSV ; bovine IgG ; preF protein ; cow’s milk allergy ; allergen ; hypoallergenic infant formula ; n/a ; IgA deficiency ; selenium deficiency ; zinc deficiency ; recommended dietary allowances ; immune system ; allergen molecules ; milk allergen micro-array ; peptides ; anaphylaxis ; milk tolerance ; diagnosis ; IgE sensitization ; children ; bic Book Industry Communication::M Medicine
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  • 61
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint serves as an introduction to the groundbreaking research work that explores the remarkable advancements in biosensor technology and its profound impact on the fields of biomedicine and environmental research. It aims to elucidate the subject's scope, provide future research directions, and highlight potential applications. This reprint is dedicated to the scientific community, researchers, and professionals seeking to expand their knowledge of biosensing. We express our gratitude to all those who have supported and contributed to this scientific endeavor.
    Keywords: live-cell immunoassay ; topographic micropatterns ; on-chip cytokine detection ; nasopharyngeal cancer ; integrated microfluidics ; retinol-binding protein 4 ; type 2 diabetes mellitus ; aptasensor ; colorimetric ; gold nanoparticles ; diagnosis ; biosensing ; fluorescent probe ; AIE ; RNA ; CAG repeats ; nucleic acid aptamer ; DNA and RNA Capture-SELEX ; small molecule contaminant ; characterization ; aptamer ; biosensing applications ; microfluidic ; impedance biosensor ; electrical impedance flow cytometer ; electrochemical impedance spectroscopy ; metal nanoparticles ; immunosensor ; MXene ; MoS2 ; graphene ; MOF ; biomarkers ; graphitic carbon nitride ; black phosphorous ; 2D-LDHs ; boron nitrides ; graphdiyne ; metal–organic frameworks ; luminescence ; surface-enhanced Raman spectroscopy ; multiplexed detection ; polymer dots ; biosensors ; fluorescent probes ; semiconducting polymers ; molecular imaging ; DNA sensor ; silver ion detection ; minidumbbell ; non-B DNA ; C·C mismatch ; cTnI ; PEC immunosensor ; bismuth vanadate ; bismuth sulfide ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 62
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Helicobacter pylori is one of the most common infections in the world, affecting roughly half of all humans. Although it is not an infection that causes death immediately after infection, it is one of the largest emerging infectious diseases in the history of humankind, causing a wide variety of diseases and, in the long term, serious complications such as stomach cancer. This Reprint contains empirical studies and reviews regarding the diagnosis, treatment, complications, and management of H. pylori infection, including new diagnostic methods, effective eradication regimens, the management of gastric cancer, and other topics.
    Keywords: gastric cancer ; biliopancreatic reflux ; gastritis ; carcinoma ; endoscopic surveillance ; Helicobacter pylori infection ; gastric stump cancer ; Helicobacter pylori ; H. pylori ; rifabutin ; treatment ; eradication failure ; culture ; bismuth ; rescue ; Hp-EuReg ; third-generation ultrathin endoscope ; transnasal endoscopy ; narrow-band imaging ; Kyoto classification of gastritis ; gastric atrophy and intestinal metaplasia ; diagnosis ; stool antigen test ; urea breath test ; peptic ulcer disease ; triple therapy ; vonoprazan ; dyspepsia ; Kyoto Classification of Gastritis ; cagA ; Okinawa ; endoscopic findings ; Helicobacter infection ; tetracycline ; eradication ; penicillin allergy ; furazolidone ; metronidazole ; amoxicillin ; child ; host genetic factor ; iron deficiency anemia ; iron demand ; iron uptake ; sports activity ; virulence factor ; gastric lymphoma ; MALT lymphoma ; radiotherapy ; chemotherapy ; rituximab ; dual therapy ; vonoprazan (VPZ) ; amoxicillin (AMOX) ; clarithromycin (CAM) ; bic Book Industry Communication::M Medicine
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  • 63
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In the face of the formidable challenge posed by global climate change, the imperative to transform the building sector into a bastion of sustainable practices has never been more urgent. The Reprint of the Topic “Building Energy and Environment” is a compendium of cutting-edge research and innovative solutions that aims to propel the construction industry towards the goals of “carbon peaking” and “carbon neutrality”.
    Keywords: low-carbon and green buildings ; building design ; building construction ; building operation ; renewable energy ; building health ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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  • 64
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Often, a project's sustainability is centred on building services and energy, but we need to have a comprehensive view of how we integrate deeper sustainability. Traditionally, we have neglected embodied carbon generated during building construction, which has led to significant carbon emissions over the last few decades, causing global warming and other related problems. The aim of this Special Issue was to collect the results of research and practice experiences in sustainable building structures, made from steel, concrete, timber, and other composite materials. Dr Roy and Dr Ananthi warmly invited authors to submit their papers for potential inclusion in this Special Issue of “Sustainable construction using steel, concrete, timber, and other composite materials”, in the journal of Journal of Composites Science.
    Keywords: ground waste tire rubber ; hollow concrete brick ; fractal ; finite element analysis ; compressive strength ; acoustic absorption ; eco-sustainability ; glass-fiber-reinforced polymer (GFRP) rods ; concrete slab ; high-volume fly ash ; moment–curvature ; ductility ; SFRC (steel-fiber-reinforced concrete) ; conventional RCC slab ; plastic hinge length ; repeated loading and composite material ; glass-fibre-reinforced polymer (GFRP) sheets ; flexural behaviour ; cracking behaviour ; load–deflection ; carbon footprint of cement ; bagasse ash composites ; green concrete ; pozzolanic ; sustainable construction ; pultruded glass-fiber-reinforced polymer ; engineered cementitious composite ; cyclic loading ; steel fiber reinforced concrete beam ; carbon fiber mesh ; jacketing ; monotonic loading ; HDPE ; quartz sand ; bitumen ; compression testing ; water absorption test ; efflorescence test ; self-sensing ; reinforced concrete beam ; mortar ; fibre ; electrical resistance ; carbon fibre ; electrically conductive filler ; brass fibre ; transfer learning ; crack detection ; concrete wall ; convolutional neural network ; structural health monitoring ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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  • 65
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Zeolites are crystalline aluminosilicates possessing a 3D network structure. They are widely considered to have been the leading materials of the last few decades in the fields of chemical engineering, energy sources, and environmental protection. Zeolites with various pore sizes can be obtained with different ratios of SiO2 and Al2O3, demonstrating large specific areas and strong gas adsorption. Therefore, they are commonly used for various processes, such as dehydration, gas separation and synthesis, air pollution control (H2S, SO2, and NOx decontamination), fuel conversion (electrolyte film), petroleum cracking, and others, playing the roles of a membrane, catalyst, and support. This Special Issue is dedicated to novel research and discussions on zeolites, with a focus on, but not limited to, the following: (1) Fundamental research on mechanisms of the formation of pores for zeolites; (2) Zeolites used as the membrane, catalyst, and support; (3) Theoretical simulation and machine learning research for zeolites; (4) Novel applications for zeolites; (5) Related porous materials
    Keywords: cerium oxide ; photocatalysis ; flash combustion ; water treatment ; air purification ; visible light ; alkali ions ; sodalite ; transesterification ; kinetics ; thermodynamic ; mechanism ; adsorption ; natural zeolite support ; single and double metal oxide catalysts ; synergistic mechanism ; SAPO-34 ; zeolites ; crystallization ; esterification ; propyl levulinate ; Zn-BEA zeolites ; dealumination ; acid–base characteristics ; propane dehydrogenation with CO2 ; propene ; Cu-SSZ-16 ; Ce content ; NH3-SCR ; low temperature ; hydrothermal stability ; zeolitic membranes ; gas separation and purification ; metal–organic frameworks ; bimetallic ; electrocatalysts ; CO2 utilization ; syngas ; zeolite ; catalyst ; pore structure ; redox ; applications ; propane oxidation dehydrogenation (ODHP) ; N2O ; Cu-BEA ; density functional theory (DFT) ; microkinetic modelling ; Mn-Ce/CuX catalyst ; zinc species poisoning ; low-temperature NH3-SCR ; benzene alkylation ; H-ZSM-5 zeolite ; Al spatial distribution ; DFT calculation ; ZSM-5 ; NOx removal ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 66
    Publication Date: 2024-03-05
    Description: The monograph is devoted to the study of dynamic processes in technical systems for various technological purposes. A new approach and methodology is proposed for a systemic, synergistic approach, taking into account the influence of energy fields of physical and mechanical effects, transformation and inversion of types of energy action. Models and equations of motion of discrete and continuous dynamic systems, dispersed media in the spectrum of their processing are considered. Changes in the parameters of subsystems are revealed: working mediums, mechanical systems, the processes of their interaction are investigated on the basis of taking into account their stress-strain state. The processes of grinding, sorting, mixing, compaction of materials and media are considered. The intensification of physical and mechanical processes, methods and means of their creation was achieved by the systematization and complexity of approaches due to the joint consideration of the mutual influence of the internal properties of subsystems. The processes of material processing by superresonant, subresonant and multi-mode parameters are investigated. Methods for determining effective parameters and modes of their operation are proposed. The processes of grinding, sorting, mixing, compaction of the processing medium in the field of vibration load are described. As a result of the research carried out, new properties of the behavior of discrete-continuous systems under power load conditions are revealed. For the first time, the stresses and deformations of both working bodies and media were taken into account to create energy-saving vibration systems for various technological processes. The carried out scientific research makes it possible to obtain the laws of change in the state of dispersed media under the action of power loads by technical systems, new technological and design solutions were proposed.
    Description: Published
    Keywords: Technical systems ; Technological media ; Grinding ; Sorting ; Mixing ; Compaction ; Cavitation ; Models ; Continuous and discrete parameters ; Force loads ; Stresses ; Deformations ; Energy ; Synergetics ; Vibration amplitude ; Vibration frequency ; Laws of motion ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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  • 67
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: This reprint, entitled “Application of data-driven method for HVAC System”, is dedicated to providing an overview of the latest achievements in the application of data-driven methods for HVAC systems. Topics of interest include, but are not limited to, the following: fault detection and diagnosis of HVAC systems; energy consumption prediction; model predictive control; data mining and analysis of HVAC systems; data mining and analysis of building environment; energy conservation; energy saving.
    Keywords: indoor air quality ; high occupancy rate ; natural ventilation ; university building ; intelligent packaging ; temperature ; humidity ; supply chain ; food waste ; food quality ; food preservation ; transportation ; grain bin ; PCM ; phase change temperature ; energy saving ; PCM latent heat ; mobile public toilets ; thermal environment ; public health security ; mechanical ventilation ; aerosol transmission risk ; underground commercial buildings ; field measurement ; air distribution optimization ; M-cycle ; evaporative cooling ; solid desiccant ; humidification–dehumidification desalination ; water production ; load data analysis ; demand side management (DSM) ; rural home hotels ; cluster control strategy ; PCM storage ; air conditioning system ; pattern recognition ; clustering ; correlation analysis ; defrosting operation mode ; low-carbon substation ; climate zones ; envelope thermal design ; window to wall ratio ; shape factor ; chillers ; fault diagnosis ; fusion ; residual ; data ; air-conditioned bed system ; heat conduction heating ; convection heating ; thermal comfort ; energy conservation ; genetic algorithm ; existing office parks ; whole life cycle ; cost benefits ; carbon reduction ; retrofit ; relative humidity ; CO concentration ; CO2 concentration ; cooking procedure ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
    Language: English
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  • 68
    Publication Date: 2024-02-27
    Description: Collective monograph contains the results of scientific research devoted to new views and proposals for the diagnosis of certain diseases. The proposed solutions are important for clinical practice and inspire optimism in obtaining encouraging results in overcoming some pathologies. Chapter 1 is dedicated to endoscopic retrograde cholangiopancreatography - a contrast study of the bile ducts and ductal system of the pancreas, which is achieved by their cannulation with the help of a flexible endoscope and their visualization by X-ray (fluoroscopy). Thanks to this, it becomes possible to diagnose and perform medical interventions for choledocholithiasis, benign and malignant obstruction of the bile ducts, chronic pancreatitis accompanied by obstruction of the pancreatic ducts. Chapter 2 presents the results of the development of a thermoelectric device for diagnosing inflammatory processes and pain syndrome in degenerative-dystrophic diseases of the lumbosacral spine. Such a device makes it possible to save, process and visualize measurement results on the display of the device and on a personal computer in real time. The results of clinical studies of thermometric indicators in the lumbosacral region of the spine in persons with chronic pain syndrome against the background of degenerative-dystrophic pathology of the spine in the presence of hernias and protrusions of intervertebral discs are given. The effectiveness of the proposed thermoelectric device in medical practice has been confirmed. Chapter 3 presents the results of the examination of various contingents of the population: students, athletes, mobile operators, people with hearing loss, post-covid syndrome and psychophysiological lability developed under martial law. The features of information processing by examinees with different degrees of functional mobility of nervous processes are highlighted. It was found that the deprivation of auditory function, post-conviction syndrome, psychophysiological lability developed in the conditions of martial law significantly reduce the level of neural processes and the ability to process information. The evaluation scales of neurodynamic and sensorimotor functions proposed for use in the medical field can be used to optimize diagnosis and increase the effectiveness of monitoring neurological morbidity, including in people with special needs. Chapter 4 is devoted to the problems of children's neuropsychiatric diseases, in particular brain damage in children with ASD. Restrained optimism is expressed for the prospect of overcoming this severe psychiatric pathology in the foreseeable future due to the introduction of genetic, biochemical and immunodiagnostic approaches, as well as metabolic and immunotherapeutic interventions with neuroprotective effects. Arguments are presented in favor of the fact that the successful testing in clinical practice of evidence-based personalized multidisciplinary strategies of diagnosis and treatment will allow a breakthrough in the clinical management of children with severe mental disorders in the near future. This will provide not only the possibility of recovery from a prognostically unfavorable and currently incurable neuropsychiatric disorder, but will also contribute to stopping the large-scale threatening epidemic of neuropsychiatric syndromes in the modern child population. Chapter 5 presents the evolution of views on the problem of Internet addiction, provides information on its prevalence, comorbidity with mental disorders, and provides an overview of modern clinical classifications and psychometric tools for its diagnosis. A single definition of "cyber addiction" is singled out, based on the fact that the object of addiction is interaction with various information resources and technical means. The proposed clinical diagnostic criteria, which are based on the criteria for the diagnosis of mental and behavioral disorders due to the use of psychoactive substances ICD-11, and the characteristics of the boundary with normative behavior when using various information resources and technical means are provided. The development and validation of a new psychodiagnostic screening tool based on the proposed cyber addiction paradigm, the YSCAS scale, is presented. The monograph is intended for doctors and practitioners who are engaged in the search and implementation of effective diagnostic methods to overcome the problems associated with the detection and treatment of certain pathologies. The monograph can also be useful to postgraduate and master's students of universities in the relevant educational and scientific profile.
    Description: Published
    Keywords: Endoscopic retrograde cholangiopancreatography ; Endoscopic lithoextraction ; Osteochondrosis of the spine ; Thermoelectric device ; Individual-typological properties ; Functional mobility ; Sensorimotor reactivity ; Autism spectrum disorders ; Attention deficit hyperactivity disorder ; Obsessive-compulsive syndrome ; Immunodiagnostics ; Internet addiction ; Cyberaddiction ; YSCAS scale ; bic Book Industry Communication::M Medicine
    Language: English
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  • 69
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The Special Issue entitled “Advances in Rock Mechanics and Geotechnical Engineering” is devoted to the publication of the latest research, field works, and laboratory investigations in the area of rock mechanics and geotechnical engineering. This Special Issue has published novel contributions in different areas of geotechnical and geomechanical engineering such as slope and embankment, tunneling and underground space technologies, pile and foundation, rock mechanics and rock blasting, excavation and leveling projects, ground improvement techniques, unsaturated soil, practical issues in soft soil, mining technology, geo-environmental engineering, new laboratory testing, applied geology for construction, and novel geotechnical construction methods. The focus of this reprint is on the development of computational methods for solving problems in the fields of rock mechanics and geotechnical engineering.
    Keywords: strength prediction ; brittle rock ; grain-structure representation ; micro-properties ; bonded block models ; Voronoi tessellation ; structure-type rockburst ; evolution mechanism ; particle flow code ; flat-joint model ; pre-grouting ; soft coal mass ; coal-grout structure ; shear behavior ; quality improvement ; rock strength ; tensile behaviour ; neuro-fuzzy ; regression ; non-destructive tests ; paste filling ; slicing mining ; false roof stability ; optimal false roof thickness ; tree-based techniques ; feature selection ; pile bearing capacity ; gradient boosted tree ; random forest ; in situ stress ; rock blasting ; crack propagation ; model test ; rheological deformation ; key stratum ; roadway groups ; roadway deformation ; surrounding rock control ; triaxial creep experiment ; cyclic loading and unloading ; elasto-visco-plastic strain ; irrecoverable strain ; tertiary creep stage ; nonlinear creep damage model ; high-altitude slope ; BP neural network ; freeze-thaw cycle ; geological conditions ; mining method ; soft broken complex ore body ; improved AHP ; comprehensive evaluation index ; blasting ; back-break ; SVM ; metaheuristic algorithms ; moth–flame optimization ; whale optimization algorithm ; tilted strata ; roadway ; nonuniform deformation ; physical simulation ; HFDEM ; numerical method ; rock fracture ; strain rate ; mining engineering ; backfill mining ; high-concentration backfill ; elastic modulus ; K-fold cross-validation ; mining ; rock engineering ; sensitivity analysis ; XGBoost ; limit equilibrium method (LEM) ; limit analysis ; accuracy ; slope stability ; homogenous slopes ; error accuracy classification chart ; physical and mechanical responses ; Egyptian granodiorite ; thermal damage threshold ; microstructure ; thermal constructions ; rock slope analysis ; limited analysis method ; numerical methods ; combined/hybrid finite–discrete element method ; FDEM ; non-renewable ; clean coal technology ; waste of resources ; “110 construction method” ; collapse settlement control ; moisture content ; dry–wet cycles ; cyclic loading ; injury mechanism ; acoustic emission RA-AF ; thermal effect prediction model ; uniaxial compressive strength ; static Young’s modulus ; artificial neural network ; multilinear regression ; rock mass ; hydraulic conductivity ; sustainability ; rock mechanics ; geotechnical engineering ; geomechanical engineering ; mining technology ; natural stones ; temperature ; fire ; thermal effect ; point load strength ; porosity ; color ; gloss ; automated mineral identification ; LBP ; classification ; texture feature ; liquefaction potential ; prediction ; Bayesian optimization ; support vector machines ; optimization ; Hoek–Brown criterion ; Mohr failure envelope ; Balmer’s equation ; limit equilibrium analysis ; modified Bishop approach ; active earth pressure ; unsaturated narrow backfill ; interlayer shear stress ; arching effect ; thin-layer element method ; tunnel excavation ; cut blasting method ; LLB method ; uncharged hole ; numerical simulation ; spectrum index ; water content ; hyperspectral information ; V-type firing pattern ; collision fragmentation ; RSA ; ANN ; coupled stress-hydro effect ; uniaxial loading ; infrared radiation ; warning threshold ; non-destructive monitoring ; alteration ; tunnel ; stress field ; deformation field ; plastic zone ; flyrock ; weathering index (WI) ; equilibrium optimizer (EO) ; particle swarm optimization (PSO) ; extreme learning machine (ELM) ; artificial neural network (ANN) ; high-water material ; seawater ; water-cement ratio ; strength ; mining method optimization ; difficult-to-mine complicated orebody ; multiple attribute decision making ; Pythagorean fuzzy sets and TOPSIS method ; mechanized upward horizontal layering method ; plateau alluvial-lacustrine deposits ; round gravelly soil ; large scale direct shear test ; shear strength parameters ; Erbil ; geotechnical characterization ; GIS ; ANFIS ; differential evolution ; firefly algorithm ; frozen rock mass blasting ; ice-filled crack ; explosion stress wave propagation ; attenuation factor ; UCS ; intelligent and statistical methods ; sedimentary rocks ; modulus of deformation ; RMR ; in situ testing ; modelling ; instrumentation ; failure risk ; element failure probability ; spatial variability ; stochastic groundwater level ; upper bound method ; rock joints ; shear strength ; scale effects ; normal stress ; JRC ; PFC simulation ; water inrush ; precursor ; strain energy ; normalized ; sustainable mine ; blast-induced flyrock ; LSSVM ; prediction models ; salt cavern ; underground gas storage ; continuum-discrete coupled method ; thermal-mechanical coupling ; thermal damage ; marble strength ; direct and indirect methods ; correlations analysis ; artificial intelligence techniques ; performance indicators ; resonant column test ; torsional simple shear test ; damping ratio ; steady-state vibration ; free vibration decay ; bibliometric analysis ; pile foundation ; sustainable structure ; VOS viewer ; Web of Science ; red clay ; desiccation cracking mechanism ; digital image correlation technology ; strain ; displacement ; mineral carbonation ; comminution energy ; stress–strain relationship ; elastic properties ; radial distribution function ; crown deformation ; underground caverns ; parametric study ; multiple linear regression ; twin tunnels ; 3D numerical analysis ; surface settlement ; field measurement ; geotechnical and geological conditions ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint focuses on the importance of the micronutrient iron in human physiological iron homeostasis and iron-related diseases. Daily adequate dietary iron supply ensures vital body functions and hemoglobin synthesis during erythropoiesis. During the last few decades, scientific evidence has shown that the maintenance of human iron homeostasis is an important factor for physical and mental health. The present reprint gives an overview of how iron, as an essential dietary element, is responsible for physiological and pathological biochemical processes in the human body. For the readership, this relevant information will provide an evidence-based update on the complex regulatory mechanisms and related diseases of iron metabolism.
    Keywords: iron metabolism ; iron homeostasis ; micronutrient iron ; physiology ; pathology ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 71
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue addresses recent advances in the research of plant-derived natural products, their mechanisms of action and how they can influence health and disease. Plant-derived natural products have been well known since antiquity due to their beneficial effects on human health, and since then, they have attracted the interest of the scientific community, leading to the identification, isolation and quantification of their compounds and research on their biomedical properties. They have been found to be rich in phytochemicals, such as terpenes and phenolic compounds, with proven antioxidant, anti-inflammatory, antimicrobial, antitumor and prebiotic properties, and therefore, they have been suggested as potential candidates for the therapeutic management of several chronic diseases. Some of them include inflammatory bowel disease, diabetes, non-alcoholic fatty liver disease, arthritis and cancer, in which inflammation, oxidative stress and dysbiosis mechanisms are implicated. Furthermore, given the increased economic burden, the side effects and the low compliance rates of patients who receive standard medical treatments, plant-derived natural products could possibly serve as adjunct therapeutic agents for chronic diseases.
    Keywords: plants ; natural products ; free radicals ; inflammation ; medicinal ; caffeic acid ; antibacterial ; antifungal ; antioxidant ; anticancer ; juglone ; Juglans regia ; mogrol ; mogroside ; phytochemical ; pharmacology ; osteoporosis ; antiobesity ; anti-inflammation ; neurodegenerative disorders ; anticancer agents ; aromadendrane ; bryophytes ; cytokinesis inhibitor ; Plagiochila species ; plagiochilins ; analgesic activity ; traditional medicine ; wound healing ; colon carcinogenesis ; 1,2 dimethylhydrazine ; hesperetin ; capecitabine ; Jatropha tanjorensis ; Fraxinus micrantha ; HPTLC ; anti-obesity activity ; high-fat diet model ; histological ; Alzheimer ; acetylcholinesterase inhibitors ; Euonymus laxiflorus Champ. ; bioactive compounds ; medicinal plants ; P. lentiscus ; GC/MS ; HPLC-DAD ; antioxidant activity ; antibacterial activity ; antifungal activity ; extract ; molecular docking ; Artemisia arborescens ; Artemisia inculta ; phenolic compounds ; terpenes ; trace metals ; antioxidant capacity ; Eurycoma longifolia Jack ; anti-inflammatory ; antinociceptive effect ; antipyretic effects ; gastroprotective activity ; gastric ulcer ; Thai traditional medicine ; phytochemicals ; inflammatory bowel disease ; gut microbiota ; Mastiha ; Curcumin ; Boswellia serrata ; Artemisia absinthium ; lipidomic profile ; Tulsi ; Ocimum sanctum ; ischemic stroke ; photothrombotic ischemia ; medicinal plant ; n/a ; bic Book Industry Communication::M Medicine
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  • 72
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Translational research is required to uncover the underlying pathomechanisms of neurological and psychiatric disorders, search for new biomarkers, and develop novel therapeutics. Complex polygenic, multifactorial, and heterogeneous mechanisms have been elucidated using in vivo and in vitro models. Advanced preclinical models have recently revealed an intriguing interaction between sex/gender and aging in the pathogenesis and clinical manifestations of neuropsychiatric disorders. Despite these advances, much work remains to be carried out to fully understand the underlying pathology of these conditions and to develop treatments that can significantly improve the lives of those who suffer from them. The current challenge in the field of neurological and psychiatric disorders is the development of disease-modifying, effective treatments for these complex and long-term debilitating conditions with a high malady burden. The first edition of this research topic, entitled 'Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models,' emphasizes the importance of translational research in bridging the gap between basic research and clinical applications. Furthermore, it provided a venue for researchers to share their findings and progress in translational research in this field.
    Keywords: Alzheimer&rsquo ; s disease ; Parkinson&rsquo ; multiple sclerosis ; stroke ; migraine ; pain ; depressive disorder ; anxiety disorder ; autism spectrum disorder ; sleep wake disorders ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 73
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: undefined
    Keywords: Medicine ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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  • 74
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Machining continues to be a hot topic within the field of Mechanical Engineering, due to the fact that it allows for high precision and surface quality. Studies around machining remain extremely active, and there is still a strong demand for knowledge and development in this area. Sectors, such as the aeronautical industry, aerospace industry, defense industry, automotive industry and mold industry, are just some of the sectors that depend heavily on this manufacturing process to produce the components that the market requires. The industry continues to require increasingly reliable and competitive solutions, and it is up to science to study means of achieving these ends. This reprint seeks to compile a series of articles that contribute to the increasing knowledge in this area.
    Keywords: Machining ; Milling ; Turning ; Reviews ; Tool wear ; Coated tools ; Fiber metal laminates ; Inconel ; Duplex stainless steels ; Machining sustainability ; Sustainable coolants ; Machining time prediction ; Machining costs prediction.&nbsp ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials
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  • 75
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    Cardiff University Press
    Publication Date: 2024-04-16
    Description: Digital and communication technologies, from cloud computing, Internet of Things (IoTs), big data and analytics, to artificial intelligence (AI), robotics and blockchain, are having a profound impact on individuals, organisations and society. The devastation caused by the global Covid-19 pandemic has highlighted the fact that digital transformation is no longer an option but a survival necessity. In the supply chain field, technology developments require companies to rethink the way they design and manage their supply chains, in order to cope with ever-growing customer expectations and to remain competitive in the marketplace. Meanwhile mega-trends and geo-political uncertainties such as Brexit, US-China trade wars and climate change have increased the pressure for supply chains to become more agile, resilient and sustainable. This edited book aims to provide readers with deep insights into how those emerging digital technologies, if deployed effectively, will allow organisations to reach the next level of operational effectiveness, and leverage emerging digital supply chain business models to transform their traditional supply chain into a sustainable digital supply chain ecosystem. The book brings together contributions from world-leading experts in supply chain digitalisation from both academia and industry, analysing cutting-edge developments observed in industries and drawing insights from the latest research in the field, such as EU Horizon 2020 project research. The contributors deliberately shy away from more established technological developments such as supply chain planning and execution systems, cloud computing and electronic platforms/networks. They focus entirely on the latest emerging digitalisation developments instead, bringing readers up to date so that they can appreciate how these are disrupting and will disrupt the status quo of supply chains. The target audiences include academics, students (undergraduates and postgraduates) and practitioners who are interested in supply chain digitalisation and transformation.
    Keywords: Digital platform; digital ecosystem; sustainability; Artificial intelligence; Blockchain or distributed ledger technology; Emerging technology; Digital transformation; Supply chain digitalisation or digitisation ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMV Management of specific areas::KJMV9 Distribution and logistics management ; thema EDItEUR::K Economics, Finance, Business and Management::KJ Business and Management::KJM Management and management techniques::KJMN Business process / operations management ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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  • 76
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Various classes of natural and synthetic molecules that can be classified as biomaterials find application in all fields of dentistry. Biomaterials should be biocompatible to minimise toxicity and bioactivity to ensure or simulate biological effects. They are used, for instance, to enhance antibacterial activity and improve the healing process. Calcium silicates, for illustration, are biomaterials used in endodontics that have proven their excellent biological, physico-chemical, and mechanical properties. However, some of these are considered too soluble, and this is almost completely due to their hardness when used as endodontic sealers, making endodontic retreatment very difficult. Despite manufacturers' best efforts, it is sometimes difficult to marry bioactivity, biocompatibility, and clinical benefits in a biomaterial; therefore, in this content, the work of researchers is invaluable.
    Keywords: calcium silicate cement ; retrograde materials ; premixed cement ; powder–liquid cement ; chemical composition ; EDX ; caries prevention ; anterior restorations ; ceramic ; dental veneers ; follow-up ; non-vital teeth ; porcelain laminate veneers ; vital teeth ; antimicrobial ; osseointegration ; surface modification ; tissue engineering ; root canal retreatment ; calcium silicate-based cement ; ProTaper Universal Retreatment ; D-Race ; dentin hypersensitivity ; desensitizing agents ; calcium phosphate ; hydroxyapatite ; nano-hydroxyapatite ; peri-implantitis ; periodontitis ; periapical radiograph ; deep learning ; neural networks ; image enhancement ; carious lesion activity ; irreversible pulpitis ; partial pulpotomy ; vital pulp therapy ; mineral trioxide aggregate ; furcation involvement ; image segmentation ; Gaussian high-pass filtering ; image preprocessing ; CNN ; calcium silicate material ; confocal laser scanning microscope ; deciduous tooth ; digital microscopy ; flowability ; micro-CT ; pulpectomy primary teeth ; root canal filling ; SEM ; zinc oxide eugenol ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The healthcare system’s ability to diagnose and care for people with schizophrenia has improved in recent decades, as effective pharmacological and psychosocial interventions are now available. However, schizophrenia remains a leading cause of disability and premature mortality. The utilization of pharmacological and psychosocial interventions in the healthcare system, which have the potential to significantly improve the quality of life for people with schizophrenia, heavily depends on medical professionals completing accurate and comprehensive assessments of patients’ psychopathologies, cognitive profiles, physical health statuses and any environmental factors that may influence them. This Special Issue reprint on schizophrenia, from the Journal of Clinical Medicine, presents a collection of articles on current approaches to assessment and treatment, as well as new findings and future perspectives of schizophrenia research and care.
    Keywords: schizophrenia ; ERP ; mismatch negativity ; MMN ; P3a ; illness duration ; real-life functioning ; motivation circuits ; negative symptoms ; RDoC ; positive valence system ; salience system ; deficit syndrome ; diagnosis ; cognitive function ; social skills training ; physical comorbidities ; childhood abuse ; internalized stigma ; neutrophil-to-lymphocyte ratio ; antipsychotics ; hypothyroidism ; inflammatory markers ; expressive deficits ; experiential deficits ; functioning ; quality of life ; first psychotic episode ; first episode ; emotional processing ; social cognition ; MCCB ; MSCEIT ; real-world studies ; real-world effectiveness ; tolerability ; treatment adherence ; second-generation antipsychotics ; long-acting injectable antipsychotics ; delusional disorders ; psychosis ; sex ; women ; psychopathology ; construct ; schizophrenia spectrum ; renaming ; rethinking ; revising ; effort expenditure ; recent-onset schizophrenia ; persistent negative symptoms ; motivation ; neuropeptide S ; cognitive functioning ; rehabilitation ; AEP ; QEEG ; switch ; extrapyramidal symptoms ; treatment ; cognitive deficits ; self-evaluation of negative symptoms ; health-related quality of life ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: In recent years, the fascination with shape memory alloys (SMAs) has grown across industries such as aerospace, automotive, naval, civil, and biology. SMAs possess unique properties, including the ability to recover from deformation when heated, exhibit pseudoelastic stress-strain behavior for large deformations, and exceptional biocompatibility for bioengineering applications. However, a comprehensive understanding of critical characteristics like transformation temperature and stress values is necessary to fully utilize SMAs. The shape memory effect, where SMAs regain their original shape after deformation under specific thermal conditions, has driven innovative applications in various sectors. In aerospace, SMAs are used in wing structures and actuation systems, enabling morphing and improving aerodynamics. In healthcare, they are integrated into orthopedic devices, simplifying surgical procedures and providing necessary support. The automotive industry also benefits from SMAs, using them in seatbelts and vibration damping systems for enhanced safety and comfort. Accurate knowledge of critical characteristics is essential for effective utilization of SMAs, unlocking their potential in different fields. The remarkable versatility of SMAs, with their deformation recovery, pseudoelasticity, and biocompatibility, positions them as a material of immense interest. As research and development continue, SMAs are poised to drive future innovations, shaping various industries.
    Keywords: shape memory alloy (SMAs) ; shape memory effect (SME) ; superelasticity ; smart materials ; constitutive models ; simulation and modeling ; smart devices ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Mg alloy is the lightest metallic structural material and possesses the advantages of high specific strength, high specific stiffness, good electromagnetism shield, good damping capacity, good machinability, and easy recycling, etc. Therefore, it has extremely broad application prospects and has drawn considerable interest in the fields of automobile, electronics, electrical appliances, transportation, aerospace, and aviation. In addition, Mg alloys are gradually showing application potential in emerging industries, serving as biodegradable metals in the biomedical field, functional material for hydrogen storage, and so on. This Special Issue (SI), entitled “Research Progress in High-Performance Magnesium Alloy and Its Applications”, presents recent developments and excellent results in the field of Mg alloys, and includes 10 articles and one editorial covering some interesting aspects of the topic.
    Keywords: grain refinement ; high strength and toughness ; {10–12} twin ; Mg-Gd-Y alloy ; multidirectional impact forging ; Mg-Zn-Mn-Ca ; Ca2Mg6Zn3 phase ; corrosion behaviors ; SKPFM ; boride ; MgB2 ; mechanical alloying ; ignition ; combustion ; flame temperature ; magnesium alloy ; biocompatibility ; surface coating modification ; corrosion resistance ; implantable bio-metal materials ; filler material ; welding ; scandium ; microstructure modification ; mechanical properties ; microstructure ; texture ; stretch formability ; high temperature cross-rolling ; annealing ; wire arc additive manufacturing ; cold metal transfer ; Al-Mg alloys ; orthogonal experiment ; Mg-Bi-Ca alloy ; hot deformation ; constitutive model ; dynamic recrystallization kinetics ; Mg alloy ; twinning ; random orientation ; compression ; room temperature ; backward extrusion ; tensile strength ; failure mechanism ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This Reprint Book provides recent studies addressing encapsulation systems for active compounds (e.g., drugs and food ingredients) to improve the quality of life around the world. The content may be helpful for the colleagues and students working on encapsulation of active compounds.
    Keywords: carboxymethyl chitosan ; mangosteen ; deodorant ; skin moisturizing ; trans-2-nonenal ; accelerated stability test ; guava ; carotenoids ; microencapsulation ; mucilage ; spray-drying ; aloe vera ; Opuntia ficus-indica ; ar-turmerone ; polymeric nanoparticles ; anticancer activity ; release study ; biodegradable polymers ; apple fiber ; trehalose ; sucrose ; blackberry phenolics ; blackberry volatiles ; starch ; Bisphenol A ; Moringa leaf extract ; encapsulating Moringa leaf extract ; nanoparticles ; alginate ; chitosan ; Ib-M peptides ; E. coli ; peptide stability ; polyethylene glycol methacrylate ; oregano ; phenolic compounds ; nanoencapsulation ; bioaccessibility ; curcumin ; zebrafish embryogenesis ; oxidative stress ; neuroprotection ; PCL nanoparticles ; paraquat ; grafted microparticles ; sodium hyaluronate ; crosslinked microparticles ; metronidazole adsorption ; adsorption isotherm ; adsorption kinetics ; metronidazole release ; polyelectrolyte ; complex coacervate ; polyamine ; stimulus-responsive materials ; controlled release ; encapsulation ; hybrids ; clay ; sodium alginate ; rosemary essential oil ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Papers collected in the present Special Issue relate to the field of sericulture. They cover different aspects based on a very ancient human agricultural activity, taking into consideration classical agronomic aspects, such as the impact of feeding on silk quality and sericulture in different parts of the world. Nonetheless, cutting edge topics are addressed as well, with papers studying silk as a biomaterial, the silkworm as a model organism, and the possibility of exploring its physiology and the molecular mechanisms that stand behind it with the aid of modern tools such as gene profiling, the CRISPR/Cas-9 system, and -omics sciences.
    Keywords: silkworm ; Bombyx mori ; transcriptome analysis ; RNA-seq ; gene model transcriptional factor ; Cutibacterium acnes ; infection ; antibacterial drugs ; polyamines ; cell cycle progression ; Bombyx mori nuclear polyhedrosis virus ; sequencing analysis ; qPCR ; pathogenicity difference ; maternal mRNAs ; 20-hydroxyecdysone ; pupa ; wandering ; fibroin ; sericin ; chrysalis ; diabetes ; hydrogen sulfide ; transcriptome ; differentially expressed genes ; expression pattern ; silk ; supercritical carbon dioxide impregnation ; nanofiller ; CRISPR-Cas ; silkworms ; genome engineering ; insect biotechnology ; entomology ; sericulture ; agroindustry ; Food and Agriculture Organization of the United Nations ; mulberry ; moriculture ; germplasm preservation ; 16S rRNA gene ; amplicon sequencing ; gut microbiota ; co-expression network analysis ; silk protein ; transcription factor ; Eri silkworm ; pentose-utilizing microbe ; lactic acid bacteria ; probiotic ; Eri culture ; silk fibroin ; SILKBridge® nerve conduit ; performance testing ; biocompatibility ; toxicology ; regulatory requirements ; quality requirements ; control manufacturing ; green material ; biomaterial ; 3D scaffolds ; cancer therapy ; bibliometric analysis ; mulberry silkworm pupae ; nutritional composition ; silk gland ; infection model ; Staphylococcus epidermidis ; insect immune response ; antimicrobial compounds ; glycopeptide antibiotics ; vancomycin ; teicoplanin ; dalbavancin ; mulberry leaves ; chemical composition ; feeding experiment ; bacterial microbiome ; BmNPV ; Bombyx mori L. ; non-timber forest product ; livelihood ; Indonesia ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Advancements in digital technologies are reshaping the world of dentistry, from prosthodontics to implant dentistry. Intraoral scanners, facial scanners, 3D printers, and milling machines have revolutionized the clinical approach and operative workflow in daily practice. However, digital dentistry brings several challenges to clinicians due to the rapid evolution of new technologies and the lack of evidence-based guidelines for their correct use. The aim of this Special Issue is to cover the latest advances in the development and application of digital technologies in prosthetic and implant dentistry. We wish to provide both clinicians and researchers with a comprehensive and up-to-date source of information on current trends, limitations, and potential future applications of digital technologies in daily clinical practice.
    Keywords: dental implants ; digital impression ; intraoral scanner ; CAD/CAM materials ; toothbrushing wear ; surface ; roughness ; surface integrity ; alveolar remodeling ; tooth extraction ; intraoral digital scanning ; imaging superimposition ; less traumatic surgery ; socket healing ; implantology ; computer-aided surgery ; image-guided surgery ; zygomatic implants ; navigation system ; dental implant ; bone level ; prospective study ; sub-crestal placement ; emergence profile ; guided surgery ; digital workflow ; stereolithographic surgical guide ; accuracy ; CAD–CAM ; DICOM–STL ; static guided surgery ; clinical study ; intraoral scanners ; digital dentistry ; impression techniques ; full-arch impression ; elderly population ; dimensional measurement accuracy ; implant scan ; operator ; precision ; scan area ; trueness ; occlusion ; overloading ; complications ; implant-supported restorations ; marginal bone loss ; oral implantology ; intraoral scan ; cone-beam computed tomography ; oral surgery ; emergence angle ; retrospective study ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Nearly 18 months later, COVID-19, caused by SARS-CoV-2, continues to present significant challenges to health systems, public health, and the economy of countries across both hemispheres. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed hospitals and clinics in many countries and continue to do so. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This Special Issue collection follows on from the Special Issue “COVID-19: Current Challenges and Future Perspectives” and provides an avenue for authors from various disciplines to provide feedback on the response to and our future global preparedness for COVID-19, as well as to disseminate critical information about SARS-CoV-2 and the associated COVID-19 pandemic.
    Keywords: COVID-19 ; new-onset DM ; severe infection ; mortality ; outbreak ; P.1 variant ; Gamma variant ; SARS-CoV-2 infection ; whole-genome sequencing ; pandemic ; overweight ; obesity ; Peru ; psychological impacts ; public health ; preparedness ; mRNA-1273 ; BNT162b2 ; TAK-919 ; SARS-CoV-2 ; post-vaccination ; healthcare personnel ; vaccination ; asymptomatic infection ; HIV ; infectious disease ; excess mortality ; regdanvimab ; remdesivir ; severe ; community transmission ; population density gradient ; Dhaka ; Bangladesh ; dengue ; undifferentiated febrile illness ; antigen testing ; variants ; reinfections ; breakthrough infections ; vaccine hesitancy ; sub-Saharan Africa ; pulmonary fibrosis ; postacute COVID-19 syndrome ; tuberculosis ; helminth coinfection ; coronavirus ; coordination ; health operations and technical expertise ; AFRO ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; liver transplantation ; reproduction rate ; phylogenetic analysis ; clade GK ; D614G ; P681R ; cross-reactivity ; haemorrhage ; thrombocytopenia ; thrombosis ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) ; molecular diagnostics ; real-time polymerase chain reaction (RT-qPCR) ; economy ; income levels ; waves ; policy ; turning points ; occupational exposure ; risk factors ; personal protective equipment ; SIR model ; socio-behavioral aspects ; interaction distance ; school reopening strategy ; self-medication ; over-the-counter ; medicine use ; Pakistan ; clinical features ; Luanda ; Angola ; socioeconomic status ; risk perception ; risk prevention practices ; qualitative ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: This reprint focuses on both advanced metals and their alloys and the areas of physical and process metallurgy, materials science, and processing techniques. Specific areas of interest also include titanium/nickel-based superalloys, intermetallics, advanced metallic materials, nanomaterials, metal matrix composites, functional materials, related synthesis and processing techniques, finite element modelling, statistical analysis, physical/mechanical property characterization, experimental validation, and other relevant phenomena. Physical metallurgy is important in the design and optimization of advanced materials with superior physical and mechanical properties through microstructural modifications and processing techniques. The goal of reprint was to bring together recent progress, novel technologies, and advanced equipment for the design and development of advanced metals and alloys and provide guidelines/benchmarks for further research in related areas. Composites, intermetallics, and nanomaterials as well as functional materials will be also included. Some of the recent advances in the field of advanced metals and alloys include novel material processing techniques, manufacturing methods and theories, microstructural characterization, modelling development, and advanced equipment. Conventional and nonconventional processes related to machining, forming, laser processing, additive/subtractive manufacturing, surface modification, and the solidification of high-performance alloys/metals are also included.
    Keywords: Fe-rich Al–Si alloy ; β-Al5FeSi phase ; cooling rate ; melt spinning ; microstructure ; strengthening mechanisms ; Zn-Mg-Ti alloy ; biodegradable metals ; mechanical properties ; cytotoxicity ; Fe-B-W alloy ; manganese ; aluminum ; molten zinc ; microanalysis ; corrosion ; hydrogenated–dehydrogenated titanium powder ; laser directed energy deposition ; mechanical property ; radio frequency plasma technique ; high entropy alloy ; bulk metallic glass ; similar element substitution/addition ; glass forming ability ; lattice distortion ; sapphire ; surface metallization ; deposition mechanism ; wettability ; low-temperature joining ; silver alloy bonding wire ; bonding strength ; vulcanization resistance ; cathodic passivation ; Mg–Nd alloy ; precipitate ; eutectic growth ; modelling and simulation ; recrystallization ; microstructure-property characterization simulation and modeling ; heat treatment and surface treatment ; TC4 alloy ; EBCHM ; aging treatment ; glass-forming ability ; corrosion behavior ; amorphous alloy ; phase transformation ; mechanical behavior ; corrosion wear resistance ; gear grinding ; white layer ; grinding temperature ; surface integrity ; AlSi10Mg alloy ; friction stir processing ; grain boundary ; texture ; dynamic recrystallization ; silver wire ; wire bonding ; chloride ions ; ion migration ; galvanic corrosion ; Cu-15Ni-8Sn alloys ; grain size ; solution treatment ; microalloying ; microstructural evolution ; laser-powder bed fusion ; MgAl2O4 ; TiB2 ; metallothermic reduction ; SHS powder metallurgy ; combustion wave propagation ; HSLA steel ; microstructural characterization ; laser welding ; thick plate ; corrosion resistance ; high entropy alloys ; lightweight ; magnesium alloys ; ultrasound treatment ; solution ; aging ; Mg17Al12 ; converter ; vortex ; flow field analysis ; numerical simulation ; steel ball ; skew rolling ; cold forming ; stainless steel ; copper–scandium CuSc ; copper alloy ; differential scanning calorimetry DSC ; precipitation kinetics ; cold-working ; cold-rolling ; activation energy ; Kissinger method ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: This Special Issue covers manufacturing of a smart polymer composites via choice of ingredients, such as polymer, filler, and additives, as well as their unique composition. It also covers the smart processing of polymer composites, which is influenced by the choice of mixers, processing condition, processing technique, etc.
    Keywords: thermoplastic polyurethane ; expanded bead ; supercritical CO2 foaming ; expansion ratio ; resilience ; hardness ; poly(lactic acid) ; lignin ; maleic anhydride ; chemical modification ; 3D printing filament ; SEBS ; membrane ; water uptake ; impedance spectroscopy ; ionic conductivity ; phlogopite ; natural rubber (NR) ; ethylene-propylene-diene monomer rubber (EPDM) ; mechanical properties ; compatibility ; nylon 6 ; polyketone ; chain extender ; hydrogen bonding ; chain branching ; chain crosslinking ; melt viscosity ; shape memory polymer ; NIR light responsive ; semicrystalline maleated polyolefin elastomer ; polyaniline ; melt blending ; adhesive ; fluorosilicone ; thermal conductivity ; magnesium oxide ; boron nitride ; syntactic foams ; hyperbranched polymer ; polyamide 6 ; hollow glass microsphere ; lubricant ; compatibilizer ; composites ; silica ; silane ; hydrolysis ; interfacial adhesion ; zinc mechanism ; hybrid flame retardant materials ; influence of gypsum ; minimum total heat release ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Supply Chain 4.0 is designed, planned, managed and optimized using Industry 4.0 technologies. There are many research issues and challenges associated with Supply Chain 4.0, a data rich complex system. The available data can interpret what happened in the past, what is currently happening, what will happen in the future and what are the best actionable decisions. Digitalization, visibility, connectivity and interoperability are integrated in Supply Chain 4.0. The operational, tactical and strategic plans across the supply chain are digitally interlinked and real-time synchronized with a 360-degree view. The win–win partnerships are dynamic and sustainable, with agility, flexibility and responsiveness to uncertain business environments. New models and methods are advocated to implement Supply Chain 4.0 research and development. With the progress and implementation of Industry 4.0 technologies, it is anticipated that there will be more and more breakthroughs in the models and methods of Supply Chain 4.0. This Special Issue will serve as a helpful reference for Supply Chain 4.0 researchers and practitioners.
    Keywords: Industry 4.0 ; supply chain management and optimization ; Supply Chain 4.0 ; supply chain analytics ; supply chain visibility and connectivity ; supply chain synchronization and coordination ; sustainable supply chain management&nbsp ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TQ Environmental science, engineering and technology
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    RAND Corporation
    Publication Date: 2024-04-14
    Description: This report discusses the information revolution in the Asia-Pacific region and its likely course over the next five to ten years. Key questions addressed in this report include the extent to which the information revolution has taken hold of markets in this region, the political implications of the information revolution for Asian governments, the variations between individual countries, and the prospects for further information-technology-related developments in the region.
    Keywords: Technology ; thema EDItEUR::U Computing and Information Technology::UY Computer science::UYZ Human–computer interaction::UYZM Information architecture ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective treatment of cancer remains a great challenge. Novel therapeutic strategies with superior anticancer ability urgently need to be discovered. In recent years, nano-drug delivery systems have been extensively investigated and applied as alternatives to conventional cancer treatments. Cancer nanomedicines aim to achieve the targeted delivery of chemotherapeutic drugs to the tumor site, utilizing strategies such as passive targeting, active targeting and stimuli-triggered drug release, while simultaneously decreasing drug accumulation in normal tissues, which together lead to improved therapeutic efficacy and reduced side effects. Currently, several cancer nanomedicines are in regular use, and several others are in various stages of development.This Special Issue will highlight recent progress in the development of novel nanomedicines and targeted drug delivery systems for cancer therapy.
    Keywords: graphene quantum dot ; targeted drug delivery ; photothermal therapy ; chemo-therapy ; polymeric prodrug ; theranostic nanocomplex ; pH-triggering releasing ; magnetic targeting ; magnetic hyperthermia ; magnetic resonance imaging ; docetaxel ; adenosine receptors ; PLGA ; nanoparticles ; lung cancer ; Notch signaling ; RBPJ protein ; drug repurposing ; fidaxomicin ; acarbose ; schaftoside ; breast cancer ; experimental skin cancer ; entrapment efficacy ; ethosomes ; metformin ; in vitro permeation ; zeta potential ; sesamol ; albumin nanoparticles ; doxorubicin ; oxidative stress ; antioxidants ; tumor-derived membrane vesicles ; cancer therapy ; tumor vaccine ; personalized immunotherapy ; low-density lipoprotein ; nanoparticle ; tumor microenvironment-responsive ; magnetic nanofluid ; improved magnetic resonance imaging ; neutral-responsive Fenton reaction ; enhanced chemodynamic therapy ; brain targeting ; folate receptor ; glioma cancer ; erlotinib ; blood–brain barrier ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    Publication Date: 2024-04-11
    Description: Describes a framework to guide assessments of the availability of data regarding U.S. anti- and counterterrorism systems, countermeasures, and defenses for planning attacks on the U.S. air, rail, and sea transportation infrastructure. Overall, the framework is useful for assessing what kind of information would be easy or hard for potential attackers to find.
    Keywords: Technology ; Transportation Studies ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::W Lifestyle, Hobbies and Leisure::WG Transport: general interest
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    Taylor & Francis | CRC Press
    Publication Date: 2023-09-12
    Description: Transition Engineering: Building a Sustainable Future examines new strategies emerging in response to the mega-issues of global climate change, decline in world oil supply, scarcity of key industrial minerals, and local environmental constraints. These issues pose challenges for organizations, businesses, and communities, and engineers will need to begin developing ideas and projects to implement the transition of engineered systems. This work presents a methodology for shifting away from unsustainable activities. Teaching the Transition Engineering approach and methodology is the focus of the text, and the concept is presented in a way that engineers can begin applying it in their work.
    Keywords: building life-cycle cost analysis;energy policies;environmental costs;global climate change;input-output analysis;local environmental constraints;resource management;sustainability;transition engineering;world oil supply ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RN The environment::RNK Conservation of the environment ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RP Regional & area planning::RPC Urban & municipal planning ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHD Classical mechanics::PHDY Energy ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TG Mechanical engineering & materials::TGB Mechanical engineering
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: The ongoing deployment of 5G networks is a key enabler for realizing upcoming services at scale, including the massive deployment of the Internet of Things, providing communications to support autonomous vehicles, and supporting the realization of smart cities. However, as the limitations of existing approaches become apparent, the need for next-generation technologies is growing, in terms of improving spectral efficiency, increasing network data rates and densification, supporting local/wide area wireless coordination, and more. In this Special Issue, we present some technologies to meet these demanding requirements and facilitate coordinating wireless networks to support future Beyond 5G networks.
    Keywords: 5G fiber optic networks ; data-driven service assurance ; next generation networks ; predictive analytics ; live-video delivery ; 5G networks ; virtualized content delivery networks ; network function virtualization ; service function chain deployment ; deep reinforcement learning ; MAC classification ; vehicular networks ; VANETs ; distributed MAC ; centralized MAC ; multi-channel MAC ; single-channel MAC ; spectrum allocation ; private 5G ; mmWave RAN ; modulation and coding schemes ; spectral efficiency ; self-organization ; self-optimization ; self-healing ; SON applications and architecture ; SON design and dimensioning ; machine learning (ML) and artificial intelligence (AI) for SON ; massive Machine-Type Communication (mMTC) ; IoT ; URLLC ; backhauling ; SON for 3G/4G ; 5G and B5G networks ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNB Energy industries and utilities
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Processing and Conversion of Oil and Gas: Modeling, Control, Simulation, and Optimization describes the core of the activity of petrochemical engineers, process controller engineers, industrial engineers, energy engineers, and researchers in the oil and gas field. This reprint explores the modeling, control, simulation, and optimization of new and revamped petrochemical processes using proven software. Thus, it offers novel illustrative examples, prospective applications, and solutions to improve these processes. This reprint aims to combine theoretical principles with examples modeled by commonly used simulation software employing steady-state or dynamic process simulation. Furthermore, applying numerical methods and optimization at both the theoretical and practical levels is within the scope of this reprint.
    Keywords: jet stability ; swirl ; twist ; dominant mode ; Brassica Napus ; fatty acid methyl esters ; 2-Ethyl-2-hydroxymethyl-1,3-propanediol ; viscosity ; batch reactor ; kinetics ; self-excited oscillation pulse jet ; nozzle ; large eddy simulation ; peak velocity ; cavitation number ; coal tar ; wash oil ; nitrogen-containing compounds ; indole ; formamide equilibrium extraction ; price bubbles ; bubble length ; petroleum products ; GSADF ; Pakistan ; pipeline safety ; risk classification ; pipeline failure ; fuzzy analytic hierarchy process ; pipeline risk assessment ; shale gas pipelines ; pressure gradient ; gas–liquid two-phase flow ; flow patterns ; Generalized Additive Model ; dimensionless numbers ; discrete element method ; optimal design ; simulation analysis ; anti-corrosion pill particles ; butyl acetate ; acetic acid ; n-butanol ; esterification ; membrane reactor ; reactive distillation ; amberlyst-15 catalyst ; energy efficiency ; economic evaluation ; methyl isobutyl ketone (MIBK) ; acetone self-condensation ; selective hydrogenation ; process development ; heat integration ; economic analysis ; nano-Pd/nano-ZnCr2O4 catalyst ; dimethyl carbonate ; dimethyl oxalate ; oxidative carbonylation ; azeotropic distillation ; profitability analysis ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: The Special Issue “Demand Response in Smart Grids” includes 11 papers on a variety of topics. The success of this Special Issue demonstrates the relevance of demand response programs and events in the operation of power and energy systems at both the distribution level and at the wide power system level. This reprint addresses the design, implementation, and operation of demand response programs, with focus on methods and techniques to achieve an optimized operation as well as on the electricity consumer.
    Keywords: demand response ; population evolution ; irrational behavior ; Markov state ; non-cooperative game ; solid electric thermal storage ; cyber–physical model ; K-means ; support vector machine ; neural network ; data analysis ; demand response (DR), load profile clustering ; k-means ; targeting of customer ; aggregator ; ramp period ; real-time simulation ; multi-objective optimization ; social welfare metrics ; energy allocation ; load disaggregation ; percentage total harmonic distortion and non-intrusive identification of load pattern ; charging strategy ; optimization ; electricity pricing ; electric vehicle ; flexibility ; flexibility market ; home energy management system ; energy flexibility ; industrial energy management ; demand side management ; control approaches ; energy management ; optimization method ; objective function ; control constraints ; Demand Response ; dynamic thermal rating ; hosting capacity ; transformer ; n/a ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues::TBX History of engineering & technology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Energy is an important material basis that can promote the development of human society. Despite the increasing use of renewable energy, the overall energy supply is dominated by fossil fuels. For a long period of time, the main consumption proportion of fossil energy will not change. With the perspective of fossil fuels such as coal, oil, natural gas, shale oil, shale gas, and combustible ice, energy exploration, reservoir reconstruction, and intelligent applications in energy exploitation and energy occurrence geology are currently explored from the perspectives of exploration and exploitation technology. This reprint summarizes the intelligent unmanned mining and its development trends and conducts various research studies, including the stratigraphic correlation of sandy conglomerate in the Yellow River Delta Sag of the Bohai Bay basin, the growth and distribution of coal-measured hydrocarbon source rocks in a mixed platform, the physical and mechanical properties of sandstone, mudstone and granite in the geological environment of deep energy reservoirs, the formation mechanism of energy reservoirs and gas reservoirs, the two-phase flow experiment and numerical simulation in energy mining, the evolution law of cracks in the surrounding rock and the reinforcement principle of gradient support, and the comparison of particle pickup by axial flow and swirling flow in horizontal pneumatic conveying.
    Keywords: intelligent mine ; smart mining ; intelligent working face ; intelligent control ; adaptive ; robotic technology ; seismic rock physics ; sandstone and mudstone ; P-wave and S-wave velocity ; pressure ; temperature ; sandy conglomerate ; Huanghekou Sag ; stratigraphic correlation ; calcite U-Pb dating ; detrital zircon ; pressure-controlled pyrolysis ; oil–water separation ; centrifugal force ; two-phase vapor separation ; cyclone separation ; Tarim Basin ; mixed platform ; delta ; coal-measure distribution ; coal-measure logging response ; axial flow ; swirling flow ; pickup behavior ; coefficient of variation ; tight sandstone gas reservoir ; nuclear magnetic resonance ; fracture ; water blocking ; n/a ; rock mechanical properties ; MMTS ; geothermal development ; geothermal reservoir ; different depth of occurrence ; gas storage ; injection production simulation ; effective permeability ; seepage law ; two-dimensional simulation experiment ; fracture evolution law ; fractured seepage zone ; gradient failure support ; hierarchical control mechanism ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues::TBX History of engineering and technology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TG Mechanical engineering and materials::TGM Materials science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: In this reprint, state-of-the-art research and review articles on emerging material systems for additive manufacturing (AM) are collected, with a focus on the process–structure–properties relationships. Additive manufacturing (AM) has grown and evolved rapidly in recent years. There are many exciting research and translational works in many areas of application, such as biomedical, aerospace and electronics. These advancements are typically coupled with materials development, which has resulted in more functionalities added to 3D-printed parts, such as multi-material fabrications and integration with machine learning or digital twins. Such enhancements in functionalities have enabled the evolution of AM from a rapid prototyping tool to an actual manufacturing solution. In this reprint, two reviews and thirteen original research articles are included to highlight the latest development in the field of materials science for AM.
    Keywords: titanium scaffolds ; 3D printing ; pore design ; selective laser melting ; lattice structures ; torsion ; design ; additive manufacturing ; functionally gradient lattice ; torsional stiffness ; energy absorption ; failure behavior ; ferritic steel ; heat treatment ; SLM ; nuclear application ; laser powder bed fusion ; solidification crack ; hot crack ; aluminum alloy powder ; EN AW-5083 ; AA5083 ; AlSi10Mg ; powder bed fusion ; metal matrix composites ; laser powder-bed fusion ; aluminum alloys ; reinforcement ; ceramic particulates ; grain refinement ; crystallographic texture ; mechanical properties ; laser-directed energy deposition ; melt pool ; process maps ; multi-fidelity Gaussian process ; Bayesian Optimization ; uncertainty quantification ; K418 alloy ; orientation ; phase ; microhardness ; color 3D printing ; penetration depth ; chromaticity ; image-based metric ; color reproduction ; Ti-24Nb-4Zr-8Sn ; titanium alloy ; biomedical engineering ; microstructure ; X-ray diffraction ; directed energy deposition ; shape-memory alloys ; joining of metals ; elemental powders ; 3D concrete printing (3DCP) ; hybrids ; geopolymer ; frost resistance ; UV radiation ; thermal conductivity ; surface finishing ; physical vapor deposition ; composites ; recycling ; polymer-matrix composites (PMCs) ; direct ink writing ; liquid deposition modeling ; glass fibers ; stainless steel ; AISI 316L ; AISI 630 (17-4PH) ; AISI 420 ; AISI 440C ; carbon content ; online monitoring ; electron beam melting ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Personalized medicine for Parkinson’s disease is a growing and emerging concept in light of recent recognition that Parkinson’s is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven “one size fits all” management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital “checklists” to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
    Keywords: Parkinson’s disease ; movement disorders ; periodontitis ; periodontal disease ; hematologic tests ; Vitamin D ; oral health ; Parkinson’s Disease ; cognition ; GABAergic signaling ; cerebellum ; MRS ; response inhibition ; non-motor symptoms ; carer stress ; older persons with Parkinson’s disease ; education ; lifestyle behaviours ; diet ; cross-sectional ; population study ; neurological disorders ; precision medicine ; genetics ; clinical trials ; Parkinson’s disease (PD) ; cognitive rehabilitation ; intervention ; deep brain stimulation ; levodopa-carbidopa intestinal gel ; apomorphine ; radiofrequency ; focused ultrasound ; induced pluripotent stem cells ; cell therapy ; gene therapy ; personalized medicine ; advanced Parkinson’s disease (APD) ; apomorphine subcutaneous infusion therapy ; pain ; intrajejunal ; levodopa ; motor and non-motor symptoms ; PKG (KinetiGrap) ; rehabilitation ; device-aided therapies ; personalised medicine ; Alzheimer’s disease ; clinical trial ; impulsive-compulsive disorders (ICD) ; dopaminergic therapy ; genetic markers ; pharmacogenetic ; polymorphisms ; insomnia ; sleep quality ; assessment ; young onset Parkinson’s (YOPD) ; Emiratis ; expatriate ; genetic ; epigenetics ; societal impact ; device aided therapies ; quality of life ; non motor symptoms ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-04-11
    Description: Herein we describe some molecular aspects of the recent anti-COVID-19 research, including some approaches making use of natural remedies, especially from medicinal plants, in silico methods, and different experimental procedures that led to the discovery of novel targets of SARS-CoV-2 and consequently novel potential COVID-19 therapeutics. COVID-19 vaccines also find mention in this book with also a description of some adverse effects reported in some cases. Considering that the different beta coronaviruses present certain conserved biomolecular mechanisms and, thus, some common therapeutic targets, finding effective therapies for a specific member of their family (such as SARS-CoV, SARS-CoV-2, and MERS-CoV) even in a scenario of a reduced impact at the time of the related disease on humankind is still relevant as it could offer or inspire efficacious therapeutic strategies not only in the context of novel pathogenic mutations of the already known beta coronaviruses, but also when future zoonoses caused by other beta coronaviruses will emergence, which is not unlikely to occur in the current world where the interactions between humans and wildlife are made more and more frequent due to the growing loss of intact ecosystems worldwide.
    Keywords: coronavirus infections ; pandemics ; natural compounds ; clove ; Syzygium aromaticum ; eugenol ; eugeniin ; SARS-CoV-2 ; COVID-19 ; phytochemicals ; herbal medicine ; catechin ; polyphenol ; tea leaf extract ; theaflavin ; virucidal activity ; MERS-CoV ; S1-NTD ; pharmacophore modeling ; ADME ; quantum mechanical calculation ; DFT ; FMO ; MM/GBSA ; molecular docking ; Molecular Dynamics Simulation ; HOMO ; LUMO ; COVID-19 vaccine ; disseminated intravascular coagulation ; heparin induced thrombocytopenia ; platelet factor 4 ; thrombosis ; thrombotic thrombo-cytopenic purpura ; vaccine induced thrombocytopenia and thrombosis ; disinfectants ; ethanol ; hand hygiene ; ozonated water ; slightly acidic electrolyzed water ; virucidal mechanism ; coronavirus ; renal disease ; nephrotoxicity ; reno-protective effect ; green tea ; epigallocatechin-3-gallate (EGCG) ; flavonoids ; natural products ; medicinal plant ; SARS-Cov-2 nsp10 ; structural similarity ; fingerprint ; ADMET ; toxicity ; main protease ; triazole ; docking ; MD simulation ; drug ; proteomic ; vaccine ; immunology ; biomarker ; cheminformatics ; phytocompounds ; systems pharmacology ; anti-COVID-19 ; drug repositioning ; molecular dynamic simulations ; binding free energy ; signal peptide ; RBD protein ; secretion ; mutant ; nucleocapsid or nucleoprotein ; structure-based drug discovery ; alphafold model and molecular dynamics ; neuroinflammation ; brain fog ; neuropeptides ; neurotransmission ; metabolism ; NSAIDs ; inflammation ; ketoprofen ; n/a ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TB Technology: general issues ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In the urological sphere, the number of tumor malignancies caused by cancer is continuously growing in Western countries. Although this is mainly due to the contemporary increase in the life expectancy of people in these geographic areas, many other factors are also contributing to this growth. Urological cancer is a complex and varied disease which affects different organs and mainly affects the male population. In fact, in most statistics, kidney, prostate, and bladder cancer are regularly included in the top-ten list of the most frequent neoplasms in males. The female population, however, has also been increasingly affected by renal and bladder cancer in the last decade. From these facts, it is clear that urological cancer is a problem of major concern in developed societies. This Topic Issue of Cancers intends to shed some light on the complexity of this field and will consider all useful and appropriate contributions from scientists and clinicians in order to improve urological cancer knowledge for patients’ benefit.
    Keywords: high-risk prostate cancer ; androgen receptor axis ; castration resistance ; neuroendocrine carcinoma ; PARP inhibition ; immunotherapy ; cancer genome ; precision targeting ; robot-assisted partial nephrectomy ; renal cell carcinoma ; indocyanine green ; nephron sparing ; prostate cancer survivors ; follow-up care ; primary health care ; general practice ; process evaluation ; Consolidated Framework for Implementation Research ; prostate-specific membrane antigen positron-emission tomography ; multiparametric magnetic-resonance imaging ; primary diagnosis ; prostate cancer ; systematic review ; diagnosis ; PSMA ; PSA ; tumor ; PET scan ; bladder cancer ; bisphenol A ; bisphenol S ; energy metabolism ; migration ; proliferation ; carbon-ion radiotherapy ; elderly patients ; radiotherapy ; particle beam therapy ; life expectancy ; systemic immune-inflammation index ; Charlson comorbidity index ; CAPRA-S ; early survival ; male incontinence ; robotic prostatectomy ; clear cell renal cell carcinoma ; ferroptosis ; prognostic model ; TCGA ; E-MTAB-1980 ; GLS2 ; pazopanib ; real-world data ; non-interventional study ; time on drug ; nivolumab ; everolimus ; trial-eligibility ; ureteral neoplasms ; urinary bladder neoplasms ; ureteroscopy ; CNTF ; CNTFRα ; LNCaP ; 22Rv1 ; castration resistant ; castration sensitive ; STAT3 ; ERK ; MMP ; biomarker ; Gleason grade ; transforming growth factor-β family ; activin ; INHBA ; INHBB ; INHBC ; prostate-specific antigen ; false-positive results ; real world-data ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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    IntechOpen | IntechOpen
    Publication Date: 2023-09-05
    Description: Following the success of the first, second and third volumes of this series, we are keen to continue our discussions on research topics related to the fields of food science, intelligent systems, molecular biomedicine, water science, and creation and theories of culture. Our aims are to discuss the latest topics, theories, and research methods in each of these fields, to promote debate among top researchers and graduate students and, in the process, to generate collaborative work.
    Keywords: bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues
    Language: English
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