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  • bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general  (1,229)
  • bic Book Industry Communication::M Medicine  (1,154)
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Global warming is imposing tremendous challenges upon human and otherwise biotic life on Earth. A warmer atmosphere holds more moisture. The consensus is that the moisture transport by the atmospheric circulation strengthens and makes already wet areas of moisture convergence wetter and already dry areas of moisture divergence drier. Therefore, the tropics and mid-to-high latitudes will get wetter and the subtropics will get drier. Without any change in the interannual variability of hydroclimate, the change in the mean hydroclimate would equally increase drought risk in some places and flood risk in others. Moreover, global warming will cause the interannual variability of the hydroclimate to intensify, which will induce more droughts and floods. Furthermore, the changing atmospheric circulation interaction with the land surface may cause storm track alterations and may play an important role in shaping moisture redistribution. The author's contributions have documented the precipitation trends in southeast of the US, the Nile River Basin Ethiopia, Iraq, the Huai River Basin of northern China, and the Qilian Mountains of western China. The precipitation predictability on both global and regional scales are also studied. The interaction among climate systems in southeast Asia is also explicitly documented.
    Keywords: El Niño ; winter weather types ; precipitable water ; surface water vapor pressure ; consistency ; interannual and long-term trend ; precipitation ; trend analysis ; Iraq ; climate projection ; CMIP5 ; groundwater levels ; rainfall ; temperature ; Mann–Kendall test ; Bayesian Ensemble Algorithm ; rainstorm process ; rainstorm intensity ; risk estimation and mapping ; CMIP6 ; risk prediction ; Southwest China ; rainstorm and flood ; spatial and temporal change ; atmospheric circulation ; rainfall change ; CHIRPS ; PERSIANN-CDR ; descriptive statistics ; non-parametric trends ; Google Earth Engine ; central Punjab ; climate change ; land cover/land use ; vegetation ; NDVI ; Huai River Basin ; trends and variability ; flood magnitude ; Qilian Mountains ; cyclones power dissipation index (PDI) ; monsoon trough ; El Niño southern oscillation (ENSO) ; Indian Ocean dipole (IOD) ; Walker circulation ; predictability ; global ; seasonal precipitation ; ENSO ; MJO ; climate trend ; land use land cover ; Nile River Basin ; water resources ; raindrop spectrum ; radar ; dynamic Z-I ; LSTM neural network ; precipitation estimation ; Loess Plateau ; spring maize ; relative soil moisture ; drought index ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RB Earth sciences::RBP Meteorology & climatology
    Language: English
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  • 2
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, recent advancements in the field of pediatric tumors are discussed, and novel prognostic markers are critically appraised. Greater understanding of the heterogeneity of pediatric cancers will ultimately lead to new therapeutic strategies with the potential to provide new prospects for precision medicine in pediatric oncology.
    Keywords: undernutrition ; obesity ; nutritional status ; childhood cancer ; overall survival ; event-free survival ; relapse ; treatment-related toxicity ; review ; sarcoma botryoides ; fertility-sparing surgery ; embryonal rhabdomyosarcoma ; genital tract ; prognosis ; treatment ; local debulking ; neoadjuvant chemotherapy ; radiation ; ovarian cancer ; adolescents ; diagnosis ; therapy ; guidelines ; children ; papillary thyroid cancer ; proto-oncogene B-raf gene (BRAF) ; craniopharyngioma ; recurrence ; risk factors ; youth ; acute lymphoblastic leukemia (ALL) ; child ; genetics ; CDKN2A/2B deletions ; fluorescent in situ hybridization (FISH) ; multiple-ligation probe amplification (MLPA) ; copy-number alterations (CNAs) ; risk stratification ; minimal residual disease (MRD) ; cardiotoxicity ; chemotherapeutics agents ; biomarkers ; omics technology ; medulloblastoma ; tumor ; histologic ; pediatrics ; micro-RNAs ; non-coding RNAs ; molecular subgroup ; stratification ; acute lymphoblastic leukemia ; proteomics ; oncology ; chemotherapy ; cardiac function tests ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 3
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: I am grateful to all the authors who contributed to this Special Issue and the referees for reviewing the manuscripts. Finally, I give my thanks to Ms. Alisa Si and all the editorial staff of Nanomaterials for their support during the publication of this Special Issue.
    Keywords: Si ; MnO2 ; rGO ; sea urchin-like structure ; lithium-ion battery ; high performance ; silica-based anode ; Ketjen Black ; electrochemical properties ; pseudocapacitor ; carbon nanotube ; polyaniline ; fractional-order circuit model ; memory effect ; fractional derivative ; zinc-ion batteries ; conducting polymers ; zinc-ion diffusion ; metal–organic framework ; supercapacitors ; energy density ; specific capacitance ; stability ; self-powered ; wearable flexible sensor ; energy harvesting ; human motion monitoring ; triboelectric nanogenerator ; NiMoO4@MnCo2O4 ; microstructure ; electrochemical performance ; cycling stability ; semiconductor superlattice ; dielectric capacity ; energy storage ; first-principles calculation ; supercapacitor ; organic crosslinked polymer ; porous carbon ; electrochemistry ; α-Fe2O3@MnO2 ; electrode materials ; flexibility ; hydrogen generation ; porous titanium oxide cage ; PtNi nanoparticles ; sodium borohydride hydrolysis ; NaBH4 ; graphene oxide ; catalytic activity ; hydrolysis ; aqueous zinc ion battery ; transition metal chalcogenides ; layered structure ; cathode ; energy storage mechanism ; g-C3N4 ; perovskite solar cells ; additive ; surface modifier layer ; Li-rich cathode material ; voltage and capacity fade ; testing mode ; cobalt-containing nanomaterials ; morphological design ; bio-derived hard carbon ; Coulomb efficiency ; Na-ion batteries ; storage mechanism ; fibrous phosphorus ; lithium-Ion battery ; anode ; CuMn2O4 ; nanosheet arrays ; hydrothermal ; battery-type ; CoO@rGO ; graphene ; MOF ; flexible electrodes ; hollow structure ; ultrafast integration ; lithium-ion batteries ; proton exchange membrane fuel cell ; mechanical vibration ; durability ; platinum migration ; accelerated stress test ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
    Language: English
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  • 4
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Land use is the projection of human activities in space, and it has become an important insight into the transformation and reconstruction of human society and economy. Rural land use in China is undergoing rapid transformation driven by the rapid development of science and technology. Effectively grasping the change and transformation process of rural land use and its internal mechanism provides an important reference for revealing the inherent laws of China's rural development. Rural land use is closely related to the rural vitalization strategy and urban–rural integration in the new era. An in-depth study of China's rural land use and policy reform provides the basis of knowledge for formulating and optimizing urban–rural relations. This Special Issue focuses on the changes, effects, and regulation of rural land use in China, focusing on its main contradictions and solutions, building a cooperative network and sharing platform for rural land use research from a multidisciplinary perspective, and further deepening the theoretical innovation and practical application of rural land use research. We invited scholars from various disciplines to contribute to the Special Issue, especially with papers on the subjects of theoretical innovation, technological innovation, and practical innovation in this field.
    Keywords: family farm ; efficiency ; DEA model ; Tobit model ; farm operation ; influencing factors ; soybean ; production pattern ; spatial agglomeration ; policy implications ; spatiotemporal changes ; crop planting structure ; black soil region ; Northeast China ; county-level ; geographic characteristics ; hollow village ; actor–network ; governance mode ; operation process ; appropriate tillage sand land ; land survey ; limiting factor ; land evaluation ; cultivated land protection ; Green Transition of Cultivated Land-use (GTCL) ; Water-Land-Food-Carbon (WLFC) ; coupling coordination ; land use change ; rural settlements ; spatial pattern evolution ; land policy ; China ; different modes ; land transfer ; livelihood capital ; difference-in-differences model ; Land Certificated Program (LCP) ; farmland “stickiness” ; land production function ; property rights ; agricultural policy ; cultivated land multifunctionality ; coupling coordination degree ; spatial-temporal pattern ; driving force ; major grain-producing areas ; northeast China ; comprehensive land consolidation ; pilot project ; decision-making evaluation ; farmers ; social investors ; non-agriculturalization rate ; ecological risk ; cultivated land change ; landform ; land management ; increasing versus decreasing balance (IVDB) ; balanced quota ; revenue ; inverted U-shaped curve ; Zhejiang province ; territorial space ; production–living–ecological space ; spatio-temporal variation ; eco-environment effect ; territorial spatial pattern ; eco-environmental quality ; soil contamination ; phytoremediation ; passivation ; farmer ; questionnaire survey ; paddy field ; dryland ; topographic gradient ; landscape characteristics ; land-use change ; rural settlement ; spatial distribution ; scale distribution ; morphological distribution ; the metropolitan fringe area ; Nanjing ; farmland transfer ; farmland function ; income structure ; rural household consumption ; consumption structure ; Yunnan Province ; farmers’ land transfer behavior ; herd effect ; geo-network ; the farmland right system reform ; creditor rights ; real rights ; agricultural modernization ; labor migration ; spatio-temporal evolution ; driving factor ; family structure ; heterogeneity ; area of land transfer ; rural–urban migration ; rural development ; land consolidation ; income distribution ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: From a biological perspective, the subterranean realm is one of the less studied, but at the same time, one of the most promising, theatres for new findings and research. Compared to those on the surface, the ecological conditions occurring in subterranean habitats are relatively simple, and this may be an optimal scenario for understanding the mechanisms allowing the colonization, adaptation, and evolution of species, as well as their interactions within local communities. Diversity in subterranean habitats is often overlooked, and few studies embrace whole communities or try to assess functional relationships between species. This Special Issue reprint comprises papers covering a wide range of aspects related to the distribution, composition, and roles of subterranean communities occurring in different typologies of subterranean habitats.
    Keywords: cave biology ; subterranean habitats ; vertebrates ; invertebrates ; community dynamics ; biospeleology ; hypogean ; conservation ; biodiversity ; troglobite ; troglophile ; trogloxene ; extreme environment ; niche ; epikarst ; classification trees ; Copepoda ; random forests ; Diptera ; Limonia ; Limonia nubeculosa ; Neolimonia ; Trichoceridea ; cave community ; prey ; food resources ; occupancy ; abundance ; Astyanax ; Spelaeomysis ; Troglomexicanus ; Speocirolana ; Toro cave ; Sierra de El Abra ; troglomorphy ; stygobite ; fieldwork ; wild fish ; comparative biology ; behavior ; troglomorphism ; olfactory test ; infrared movies ; amino acids ; chondroitin ; plasticity ; cybernetics ; ecology ; cavefish ; dissolved oxygen ; cave evolution ; Astyanax mexicanus ; Ostracoda ; Yucatán Peninsula ; cenotes ; mitochondrial marker ; geometric morphometrics ; population ecology ; growth ; movements ; São Domingos karst area ; subterranean fishes ; evolution ; origin of troglobites ; Brazil ; subterranean biology ; environmental science ; biogeography ; distribution records ; groundwater ; underwater caves ; cenote ; mysid ; stygobiont ; bioindicator ; accidental cave visitors ; Arachnida ; Araneae ; arid ; levant ; Mediterranean ; species diversity ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSV Zoology & animal sciences
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Metronomic chemotherapy is now, finally, in clinical use. After 20 years of preclinical development and clinical trials, the emerging data will be of paramount importance in allowing us to assess the impact of metronomic chemotherapy on different tumor types. Indeed, it is likely that the next decade will see a major reassessment of the possible applications of metronomic chemotherapy, both alone and in combination with new therapeutic approaches such as immunotherapies, for the management of cancer. Moreover, the results of clinical trials will likely profoundly affect the direction of the laboratory efforts that are going on in parallel and aiming to improve the personalization of this therapeutic strategy. This Special Issue is our attempt to cover the past and present clinical results that have brought us to this pivotal moment and will form the basis of future clinical developments. Scientists and clinicians caring for cancer patients are well aware of the challenges in dealing with this particular therapeutic approach; one such challenge is obtaining improvements in patient survival without significant toxicity. This edition includes clinical research on chemotherapy and ongoing controversies related to metronomic chemotherapy.
    Keywords: metronomic ; oral cancer ; oral squamous cell carcinoma ; metronomic chemotherapy ; metastatic castration-resistant prostate cancer ; cyclophosphamide ; side effects ; pediatric tumors ; etoposide ; valproic acid ; prostate cancer ; CRPC ; castration ; capecitabine ; paclitaxel ; immunomodulation ; angiogenesis ; microbiome ; breast cancer ; safety ; preclinical studies ; clinical studies ; pharmacokinetic studies ; biomarkers ; chemo-free ; DLBCL ; diffuse-large-b-cell-lymphoma ; elderly ; frail ; comprehensive geriatric assessment ; chemo-endocrine therapy ; FulVEC ; pediatric oncology ; brain tumors ; pharmacology ; medulloblastoma ; ATRT ; immunotherapy ; lymphoma ; vinorelbine ; checkpoint inhibitors ; bic Book Industry Communication::M Medicine
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The green mining of coal resources aims to realize the best economic and environmental benefits in the process of coal resource development, which is relevant to the sustainable development of the earth. Green mining technologies include the following: water-preserved mining for water resource protection; filling mining for the protection of the earth and buildings; simultaneous extraction of coal and gas for the realization of gas discharge; intelligent green mining to realize emission reduction; clean energy development in mining enterprises for the realization of resource transformation; and water and soil ecological restoration for the ecological protection of mining areas.
    Keywords: residual coal pillar ; gob-side entry driving ; extra-thick coal seam ; coal pillar size ; surrounding rock control ; directional long borehole ; long-distance ; heading face ; permeability evolution ; gas pressure evolution ; gas drainage ; pre-splitting blasting ; roof cutting technology ; hydraulic fracturing ; no-coal pillar mining ; thick hard roof ; pressure relief technology ; sandstone ; deformation behavior ; mining stress path ; coal ; solid propellant blasting ; borehole wall pressure ; damage fracture law ; experimental study ; main roadway group ; mining-induced stress ; surrounding rock stability ; ground control ; deflection of principal stress ; close-distance coal seams ; stopping space ; roof rocks ; stability ; asymmetric control ; deep mine ; coal roadway ; numerical simulation ; pressure relief ; external anchor–internal unloading ; surrounding rock control technology ; multi-seam mining ; gas emission of working face ; hydrocarbon isotope ; gas emission rate of adjacent coal seam ; mining fracture zone height ; fully mechanized top coal caving mining ; triangle-block structure ; beam structure ; cable truss ; support ; mining pressures ; gob-side coal roadway ; asymmetric floor heave ; failure mechanism ; cooperative control ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning
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  • 8
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on topics related to spintronic devices, such as spin-based magnetoresistive memories, multiferroic interconnects and sensors, microfluidic solenoid valves, and magnetoelectric antennas with broad practical applications.
    Keywords: optimization design ; magnetic isolation ring ; dynamic response characteristics ; simulation ; transition jitter ; heat-assisted magnetic recording ; magnetic footprints ; antenna miniaturization ; ME antenna ; mason equivalent circuit model ; finite element simulation ; high gain ; electrodeposition ; permalloy ; magnetoresistance ; MOKE ; AMR ; FMR ; planar hall effect ; gradiometer ; magnetic sensor ; synthetic multiferroic ; interconnects ; magnetic logic devices ; spintronics ; spin-transfer torque magnetic tunnel junctions (STT-MTJ) ; Ising annealing system ; combinatorial optimization problem ; magnetostriction ; magneto-deformation ; magnetoactive elastomer ; normal force ; hysteresis ; magnetorheological elastomer ; finite element method ; micromagnetics ; spin and charge drift-diffusion ; MRAM ; SOT-MRAM ; temperature scaling ; temperature effects ; incubation time ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHK Electricity, electromagnetism & magnetism
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  • 9
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Bee products, such as honey, bee pollen, bee bread, royal jelly, propolis, and bee-related insect foods, are widely consumed as natural/functional foods or supplements, owing to their nutritional/bioactive characteristics, which are beneficial to human health. However, the bee products currently on the market vary in quality, leading to serious concerns among consumers. Various factors influence the quality of bee products, such as the standardization of bee breeding and product production, environmental and climatic conditions, artificial blending, and the residues of hazardous substances. In order to improve the quality of bee products and promote the healthy development of the bee product industry, it is vital to strengthen the quality evaluation system of bee products based on their physicochemical and biological characteristics, such as the distribution of different nutrients, the residue detection of hazardous substances, the characterization of botanical or geographical markers, the identification of genomic characteristics, and the determination of biological/functional activities. We invited submissions to this topic on the “Quality Evaluation of Bee Products”.
    Keywords: bee products ; quality evaluation ; distribution of nutrients ; residues of hazardous substances ; botanical or geographical markers ; genomic characteristics ; biological/functional activities ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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  • 10
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Natura is a polysemic Latin word that has accompanied the historical development of the West for centuries, spreading around much of the globe with colonialism and imperialism. It has been adopted in numerous languages. Our relationship with nature has become a highly charged issue at least since the "ecological turn" around 1970. It is as much about the relationship of humans to the environment as it is about the relationship of humans to each other. In the course of these debates, research has intensified in various disciplines: history, anthropology, philosophy, literature, ecology, etc. The nine contributions gathered in this volume deal with the dimension of perception and its long-term development from the Middle Ages to the present time. They trace in detail how images of nature were adopted, modified, and transmitted for specific purposes in specific situations. The introduction to the volume provides an overview and brings the contributions together.
    Keywords: nature ; culture ; science ; religion ; European history ; scholasticism ; image of man ; Thomism ; medieval medicine ; anthropology ; Magnus Hundt ; human body ; Japan ; history of ideas ; environment ; pollution ; ecology ; physico-theology ; nature as a huge organism ; Alfred North Whitehead ; philosophy of nature ; philosophy of subjectivity ; metaphysics ; Donna J. Haraway ; anarchism ; naturalism ; Fin de Siècle ; pedagogy ; historical anthropology ; history of biology ; symmetrical history ; medieval breeding ; race ; ancestry ; Aristotelianism ; Albertus Magnus ; practical knowledge ; natural philosophy ; seventeenth century ; atomism ; corpuscles ; Humboldtian science ; barbarism ; savage ; civilization ; indigenous knowledge ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
    Language: English
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This collection of articles provides insight into the mental health and nursing care of individuals who are confronting a life-threatening illness. As individuals face a cancer diagnosis, there will be many challenges and changes in their lives. Emotional distress can emerge to greater and lesser degrees. Frequently, these individuals will require additional assistance to cope with the emotional distress they experience. Nurses have an important role in assessing this emotional distress and providing relevant interventions.
    Keywords: Latinx ; family ; meaning ; communication ; coping with advanced cancer ; delirium ; liaison nurse ; misrecognition of delirium ; coordination ; breast cancer ; psychological distress ; quality of life ; women’s health ; qualitative study ; cancer care ; older adults ; mental health ; feeling safe ; home-dwelling ; patients with terminal cancer ; caregivers ; competency in anticipatory grief counseling ; emotional care ; person-centered care ; qualitative research ; anxiety ; depression ; family involvement ; hepatocellular carcinoma ; palliative care ; cancer ; decision-making ; nurse ; caregiving self-efficacy ; family caregiver ; oral cancer ; oncology ; nursing ; clinical nurse specialists ; cancer patients ; expanding nurses’ authority ; professionalization ; policy ; education ; bic Book Industry Communication::M Medicine
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  • 12
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Obstructive sleep apnea is a highly prevalent disorder with strong associations with cardiovascular, cerebrovascular, metabolic, and cognitive consequences, including drowsy driving. Positive Airway Pressure treatment is the first-line therapy for adults with obstructive sleep apnea who are symptomatic. However, many individuals with comorbidities do not report symptoms that are associated with the disorder, and adherence to treatment is poor, especially in individuals with cardiovascular diseases. This reprint contains reviews and original articles that aim to update the current perspectives on the treatment modalities of obstructive sleep apnea to highlight multidisciplinary approaches, personalized treatment strategies, and the identification of the predictors of a patient’s response to treatment, both in the general population and in clinical cohorts.
    Keywords: obstructive sleep apnea (OSA) ; continuous positive airway pressure (CPAP) ; mandibular advancement devices ; upper airway surgery ; drowsy driving ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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  • 13
    Publication Date: 2024-01-08
    Description: Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management of primary non-response and secondary loss of response to biologics, while cumulative evidence suggests that proactive TDM is efficacious for optimizing anti-tumour necrosis factor (anti-TNF) therapy in patients with IBD. Proactive TDM can be very useful for optimizing biological therapy in specific IBD populations, such as pregnant women as well as patients with perianal fistulizing Crohn’s disease and acute severe ulcerative colitis who are characterized by high drug clearance. Preliminary data suggest that proactive TDM may also have a role in de-escalating anti-TNF therapy in patients in clinical remission including stopping the immunomodulator when combined with anti-TNF therapy. However, several knowledge gaps and limitations hinder the wide implementation of TDM in clinical practice, including the optimal drug concentration to target the lag time between sampling and results and the lack of harmonization of TDM assays. Recent advances regarding the role of TDM include the use of rapid point-of-care assays and the incorporation of model-informed precision dosing. The aim of this Special Issue is to highlight the clinical utility of TDM and discuss the barriers and recent advances of TDM of biologics in IBD and other IMID.
    Keywords: ulcerative colitis ; Crohn&rsquo ; s disease ; inflammatory bowel disease ; infliximab ; adalimumab ; certolizumab pegol ; golimumab ; vedolizumab ; ustekinumab ; therapeutic drug monitoring ; immunogenicity ; rheumatoid arthritis ; ankylosing spondylitis ; psoriasis ; clearance ; model informed precision dosing ; bic Book Industry Communication::M Medicine
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-12
    Description: Scientific motivation to publish this book comes from the increased interest in the study of toxoplasmosis, showed all over the world. Though the Toxoplasma gondii infection was first discovered in 1908, toxoplasmosis remains a today's research topic, a realm of questions and dilemmas that interest both the veterinarians and the human doctors. Studies in the field are directed to the epidemiology of the disease, the sources of infection, epidemiological chains, being underlined the important feature in the transmission of this parasite: the ability to pass from one intermediate host to another intermediate host without passing through the final host - felids. An increased prevalence of toxoplasmosis in humans and animals, as well as the difficulty of coproscopic diagnosis of toxoplasmosis in cats, expensive serological examinations in both animals and humans, lack of diagnostic methods accessible to veterinarians in slaughterhouses, cultural and culinary differences of human patients, which can influence the prevalence of the disease, motivate the scientific and practical importance of the proposed book and reveal the importance of this topic for animal and human health. So, the proposed book will contain informations regarding the etiology and history of Toxoplasma gondii infection and also the parasite's morphology and biology. This work will contain a very detailed epidemiology of the toxoplasmosis from all over the world and for all species of animals. This chapter will include also personal findings of the authors about the Toxoplasma gondii seroprevalence in domestic animals from Romania. In the last part of the book we will present the main methods for toxoplasma diagnosis. At the end of the book we will synthesize the main routes for T. gondii infection and the recommendations for reducing toxoplasmosis seroprevalence.
    Keywords: Toxoplasma gondii; animals; humans; seroprevalence; prevention; control ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The global transition toward a renewable energy-centric energy matrix represents a focal point of interest for the international community in the pursuit of mitigating environmental pollution and combating climate change. This reprint advocates for the proposition of technologically advanced solutions, emphasizing heightened efficiency, superior energy integration, and cost-effectiveness. Such advancements are poised to accelerate the widespread adoption of renewable energies, thereby propelling collective endeavors towards sustainable development. Within the intricate framework of energy systems, energy storage stands as a cornerstone, providing indispensable attributes such as continuity, stability, and security of service. The seamless integration of energy storage systems into renewable energy technologies emerges as a pivotal imperative. This strategic integration addresses the challenge of intermittency, ensuring prolonged utilization of renewable sources and contributing significantly to the decarbonization of both centralized and distributed electrification systems. This reprint amalgamates pioneering research, offering a scholarly foundation that will propel the sustainable development of energy storage integration. Positioned as a valuable resource, it informs decision-making processes in both the public and private sectors, steering them towards a more resilient and environmentally conscious energy landscape.
    Keywords: photovoltaic and thermal solar energy ; wind energy ; artificial intelligence applied to clean energy systems ; microgrids ; energy storage in batteries: lead&ndash ; acid, lithium-ion, nickel&ndash ; cadmium, flow batteries, others ; control of electrical systems ; renewable energies ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 16
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue includes 14 papers by authors from Italy, USA, Egypt, Brazil, Russia, Indonesia, Czech Republic, China, Lithuania, the Netherlands, and Greece, dealing with several topics. The spatial distribution of soil organic carbon is useful for improving crop productivity and assessing the effect of agronomic management on crops and soil. Two interpolation methods and remotely sensed images were used in two papers. Other papers dealed with the use of zeolite-rich tuff in olive growing to reduce mineral fertilization, tested the effectiveness of green manure crops in providing nutrients and supplementing traditional fertilizers, and proposed composted sewage sludge as a source of micronutrients for crops. Since soil-borne diseases worsen the fertility, other authors studied the bacteria in the rhizosphere of saffron. Mapping and modeling soil suitability and capability under intensive land use in drylands with multivariate analysis was the topic of another paper, as was the evaluation of forest patches for preserving water regulation in tropical landscapes. Other findings regard agricultural conservation practices that reinforced the small water cycle and the comparison of deep-rooted vegetal covers for stabilizing slopes or repairing shallow landslides. Moreover, industrial solid waste can be a liming material to reduce soil acidification, increase crop productivity or amend soil; low-peat mixtures are able to provide C sequestration, climate regulation, and functional diversity services, while low-intensity management of high mountains can preserve seed-rich habitats for farmland avifauna.
    Keywords: soil management ; soil ecosystem services ; agricultural land ; agricultural ecosystem ; agricultural conservation practices ; soil chemical properties ; soil organic matter ; SOC spatial distribution ; small water cycle ; biodiversity ; functional microbial diversity ; urban soil ; remote sensing ; regression kriging (RK) ; multivariate adaptive regression splines (MARS) ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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  • 17
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue is a collection of eleven articles (five reviews and six studies) that describe a wide range of approaches to modulating metalloproteinase activity in disease. The techniques described are in vitro, in vivo, and ex vivo.
    Keywords: carbohydrates ; glycoconjugates ; MMPs ; ADAMs ; iminosugars ; metzincin inhibitors ; matrix metalloproteinases (MMPs), protease ; tissue inhibitors of metalloproteinases (TIMPs), exosite ; small molecule inhibitors ; monoclonal antibodies ; proteomics ; N-terminomics ; terminal amine isotopic labeling of substrates (TAILS) ; MMP-2 ; MMP-9 ; Alzheimer’s disease ; AD ; neurodegeneration ; neuroinflammation ; natural compounds ; marine compounds ; terrestrial compounds ; nutraceuticals ; Matrix Metalloproteinase inhibitors ; bone targeting ; bisphosphonates ; antitumor agents ; skeletal malignancies ; osteoarthritis ; cartilage ; metalloproteinase ; targeting ; meprin α ; meprin β ; zinc metalloproteinase ; medicinal chemistry ; probe development ; uHTS ; dipeptidyl peptidase III ; coumarin derivatives ; inhibitor ; molecular modeling ; β-blockers ; carvedilol ; matrix metalloproteinase-2 ; ischemia-reperfusion injury ; isolated heart perfusion ; kidney ; obeticholic acid ; ischemia/reperfusion ; liver ; metalloproteinases ; MMP-2 inhibitor ; cardiac dysfunction ; ischemia ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint is a comprehensive compilation of both new discoveries and methods related to nature hydrate and deep-water hydrocarbon. This reprint contains the advanced methods used in natural gas hydrate and deep-water hydrocarbon exploration. Its scope ranges from the East China Sea to the South China Sea and the Southeastern India Ocean. The reprint particularly focuses on the many innovative technical developments that have emerged in this field, and explores the various ways we may achieve renewable energy integration. The reprint provides a valuable resource for researchers, practitioners, and policymakers who are interested in the challenges and opportunities associated with natural gas hydrate and deep-water hydrocarbon exploration.
    Keywords: natural gas hydrate ; deep-water hydrocarbon ; geochemical characteristics ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the IBD classification are ulcerative colitis (UC) and Crohn’s disease (CD), sharing similarities but exhibiting distinct differences, sometimes making their discrimination challenging.A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by the robust and persistent infiltration of immune cells and compromised intestinal barrier integrity, leading to a phenomenon known as “leaky gut.” Inflammation can manifest acutely or chronically, known as relapsing, and can increase in severity over time, thereby causing life-long morbidities and reduced quality of life for affected individuals, underscoring the need for a deeper comprehension of the molecular contributors to disease pathogenesis and progression.
    Keywords: inflammatory bowel diseases ; cell autofluorescence ; immune cells ; NADH ; FAD ; flow cytometry ; multiphoton microscopy ; colitis ; colitis-associated cancer ; inflammatory bowel disease ; colorectal cancer ; colon adenocarcinoma ; ulcerative colitis ; Crohn’s disease ; cDNA microarray ; transciptomics analysis ; microarray ; inflammatory bowel diseases (IBDs) ; vasculature ; angiogenesis ; gut vascular barrier ; vessel permeability ; epithelial barrier ; homeostasis ; acetylcholine ; muscarinic receptor ; non-neuronal acetylcholine ; mucosal wound healing ; ferroptosis ; leaky gut ; inflammatory bowel disease (IBD) ; triple-culture ; Caco-2 ; HT29-MTX-E12 ; THP-1 ; monocyte-derived macrophage ; inflammation ; TEER ; FITC-dextran 4 kDa (FD4) ; pro-inflammatory cytokines ; HIF-1α ; PHD2 ; AKT ; intestinal epithelial cells ; probiotics ; LPS ; antigen-specific T-cells ; celiac disease ; gliadin ; IBD ; food antigens ; intestinal Behcet’s disease ; immune mechanism ; biological agents ; claudin ; tight junctions ; barrier function ; gut ; ZO-1 ; actin ; cell migration ; cell division ; colon cancer ; PMNs ; LDs ; FOXO3 ; n/a ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Wine has a complex matrix with many volatile compounds present, which evolves over time. These volatile compounds are important to wine quality as they contribute to the aroma and varietal characteristics of wine. Recent development in the analysis of volatile compounds in wine has greatly improved our understanding of the complexity of wine aroma. Analytical methods used for wine aroma fingerprinting have shown potential in determining the origin and quality of wine. Thus, research on volatile compounds responsible for wine aroma and their correlation with wine provenance and wine quality have increasingly attracted great interest from researchers and winegrowers. This Special Issue presents the latest research regarding wine aroma compounds, including, but not limited to, the topics on the characterization of aroma compounds in grapes and wine, factors influencing the production of aroma compounds in wine during fermentation and maturation, and analytical methods for wine aroma analysis.
    Keywords: marselan wine ; aroma compounds ; indigenous yeast strains ; Saccharomyces ; non-Saccharomyces ; icewine ; Vidal ; yeast ; sensory analysis ; amino acid ; fruity ester ; wine aroma ; nitrogen management ; Pearson correlation analysis ; carbon metabolism ; Vitis davidii Foёx ; spend coffee grounds ; fermentation ; sensory property ; volatile profile ; yeast protein hydrolysate ; nitrogen supplementation ; volatile compounds ; wine higher alcohols ; wine esters ; monoterpenes ; triangle test ; check-all-that-apply ; correspondence analysis ; Cochran’s Q-test ; nutrients ; central composite design ; Saccharomyces cerevisiae ; wine ; strain effect ; aromas ; non-Saccharomyces yeasts ; ethanol tolerance ; ultraviolet irradiation ; diethyl sulfate mutagenesis ; vineyard mechanization ; phenolics ; sensory properties ; anthocyanins ; bentonite ; cold soaking ; colour ; pathogenesis-related proteins ; Pinot noir ; tannin ; antioxidants ; glutathione ; glutathione-enriched inactivated dry yeasts ; methoxypyrazines ; oxidation ; Sauvignon Blanc ; thiols ; aroma profile ; grape pomace ; model juice ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The term fertilizer use efficiency (FUE) is not new. However, in recent years, improving the FUE has become particularly significant. This is due to growing demographic pressure, limited natural resources, climate change, and challenges related to environmental protection. This Special Issue of Plants contains papers that describe the current status of the knowledge and outlook of FUE improvement. The two review articles included provide an opportunity to become acquainted with the factors influencing FUE and contemporary trends in the development of fertilization strategies and technologies aimed at maximizing the value of this indicator. Of note, the concept of effective fertilization is presented and defined as the soil fertility clock (SFC). The 19 original articles included in this reprint present the results of research on the following: optimal N dose determination, balanced N fertilization, nitrogen use efficiency (NUE), foliar fertilization, improving the effectiveness of phosphorus use, and the possibility of improving FUE through the application of innovative fertilizers. Thanks to all the articles, this Special Issue enriches our knowledge in terms of the assessment methods of FUE in plant production. Moreover, it indicates new possibilities, perspectives, and directions for the development of scientific research within this field in the coming future.
    Keywords: Soil acidity and nutrient uptake ; Critical stages of nutrient requirement by crop plants ; Effect of nutrients on yield component formation ; Nutrient balance ; Macronutrient impact on crop growth rate and physiological determinants of yielding ; Nutrients and tolerance to abiotic and biotic stresses ; Nitrogen use effectivity ; Urease and nitrification inhibitors ; Crop plant quality ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue, entitled “Geochemistry and Mineralogy of Ni-Co Laterite Deposits”, presents an updated overview of Ni-Co laterites as sources of Ni and Co but also of other metals of interest, such as Sc, PGE or REE. This collection is composed by researchers from different fields. The Special Issue starts with two general descriptions of previously unknown laterite deposits, a clay-type Ni-laterite deposit from Cuba and a magnesium silicate Ni-laterite deposit from the Philippines. It follows with four papers focusing on the occurrence of Co, Sc and other critical metals located in current tropical environments (the Dominican Republic, Venezuela and Brazil) as well as non-tropical environments (the Balkan peninsula, Spain and Chile). The three following papers deal with novel techniques or methodologies to improve the characterization of the Ni-laterite profiles, involving the use Al as a Sc proxy, water correction of in situ portable XRF analyses, and the study of hyperspectral data using quadrant scan. The next paper focuses on the silicification commonly observed, yet understudied, in some Ni-laterite profiles using oxygen and silicon isotopes. And finally, the last contribution examines the presence of unusual minerals (diamond, SiC) in Ni-laterite breccias.
    Keywords: Fe–Ni–Co laterites ; critical metals ; REE ; PGE ; Cr(VI) contamination ; spectral data ; mineralogical data ; lithological boundaries ; nickel laterite ; New Caledonia ; quadrant scan ; Ni-laterites ; mineralogy ; breccia ; uranium ; SiC ; combined analyses ; Raman ; nickel laterites ; lateritization ; serpentinization ; weathering ; goethite ageing ; pXRF ; mine ; nickel ; iron ; water content ; dilution law ; Beer-Lambert law ; saturation ; scandium ; laterite ; Ni-laterite ; sequential extraction ; cobalt ; manganese ; lithiophorite ; asbolane ; Ni-Co laterite ; Piauí ; metal cycling ; cobalt speciation ; biogeochemistry ; redox cycling ; silcrete ; pseudo-karst ; oxygen and silicon isotopes ; Sc ; Co ; Ni-rich serpentinite ; Mn-oxyhydroxides ; smectite ; serpentine ; clay-type ; Cuba ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint focuses on the latest advances in the field of the 3Rs, as applied to laboratory animals. The continuous progress in the application of the 3Rs will allow for us to achieve a more humane and equally competitive science, improving animal welfare.
    Keywords: replacement, reduction, refinement, disease models, human-animal interaction, translation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFF Social issues & processes::JFFZ Animals & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: To ensure global food and nutrition security, there is a need for a sustainable year-round supply of nutritious food systems such as fruits and vegetables. Over the years, there has been a surge in fruit and vegetable consumption due to their composition of health-promoting biomarkers such as vitamins, minerals, fiber, and bioactive polyphenols. However, producing fruits and vegetables with the valuable contents of these health-promoting biomarkers is dependent on various factors, such as growing degree days, genetic pool, and management practices. Thereby, the goal of this Special Issue (Fruits and Vegetables Production) of the MDPI journal Plants was to provide up-to-date knowledge on traditional and emerging novel technologies applicable in sustainable production of high-value fruits and vegetables at various stages of their field and greenhouse production chains. In summary, this reprint is produced from the Special Issue that reported 12 peer-reviewed manuscripts, with foci on: (1) crop response to different elicitors and (2) green non-destructive technologies for efficient profiling of biomarkers, quality parameters, and cultivar evaluation. Thus, this reprint bridges the gaps among stakeholders (i.e., researchers, policymakers, and industry) for efficient production of consumer-centric crops with high productivity, appreciable nutritional value, and post-harvest resilience.
    Keywords: antioxidant ; Brassica oleracea ; chlorophyll index ; membrane injury ; stomatal conductance ; water deficit ; water use efficiency ; rhizobacteria ; PGPR ; nutraceutical quality ; Solanum lycopersicum ; biostimulant ; pyroligneous acid ; vegetable production ; post-harvest ; Capsicum annuum L. ; maturation ; nutritional quality ; seed chemical composition ; β-carotene Cucumis melo ; flavonoids ; mineral element ; vitamin C ; fruit quality ; quality prediction ; plant phenotyping ; orchard management ; grape ; histamine ; putrescine ; agmatine ; dopamine ; spermine ; organic amendment ; plant metabolites ; soil health ; environmental health ; anthocyanin ; russeting ; silver patch ; Solanum tuberosum ; suberized cell layer ; surface cracking ; microgreens ; natural amendment ; phytochemicals ; healthy food ; common bean ; magnetic field ; photosynthesis ; physiological parameters ; seeds ; Carica papaya ; cultivation practice ; fruit development ; fruit tree ; greenhouse ; mineral distribution ; papaya fruit ; skin coloration ; nutrient ; ripening stages ; tropical ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint combines 11 quality review and research articles on active and intelligent food packaging polymers. We anticipate that the contributions gathered within this Special Issue not only reflect the current state of the field but also serve as a catalyst for future advancements. Together, we aim to unravel the intricacies of active and intelligent food packaging, paving the way for a safer, more sustainable, and technologically enriched future in the realm of food preservation.
    Keywords: biopolymers ; compost ; soil ; aquatic systems ; biodegradation assay ; food packaging ; antimicrobial film ; antioxidant film ; active packaging ; EVOH copolymer ; methyl anthranilate ; melt-extrusion ; film properties ; antifungal activity ; cellulose nanocrystal ; silver nanoparticle ; hydrothermal green synthesis ; colorimetric freshness indicator ; intelligent packaging ; active compounds ; food additives ; food toxicity ; functional foods ; nano-encapsulation ; orange juice ; physicochemical characteristics ; microbial stability ; shelf-life ; lignin nanoparticles ; thymol ; polybutylene succinate ; antimicrobial packaging ; biodegradable materials ; thermochromic inks ; chemical resistance ; UV radiation ; color degradation ; anthocyanin ; Clitoria ternatea L. ; ultrasonic extraction ; pH-responsive indicator ; food freshness ; titanium dioxide ; photocatalytic activity ; ethylene-removing ; nanocomposites ; eco-friendly materials ; oxygen scavenger ; multilayer film ; volatile organic compound ; VOC ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint describes the fate of pollutants transported to the sea from the mainland and how they accumulate in the marine environment and organisms. This will contribute to increasing the knowledge on the dangers of pollutants that reach the marine environment and their fate once they enter the marine food chain. We also hope to improve knowledge on the effects of the pollutant load on the sea during all the seasons, due to the contribution of rivers, rainfall, etc., and the relative influence on marine organisms.
    Keywords: Adriatic Sea ; Neretva Channel ; sediment dynamics ; age model ; metal concentrations ; toxic element ; Mediterranean Sea ; sponges ; biomonitoring ; northern Adriatic Sea ; anthropic signal ; trace metals concentration ; marine sediments ; zoobenthos ; sentinel species ; suspension feeders ; water pollutants ; bioaccumulation ; heavy metals ; trace metals ; beach sediments ; coastal processes ; lithology ; pollution indicators ; surficial sediments ; central western Adriatic Sea ; marine dumping area ; heavy metal ; dredged material ; benthic community ; Huangmao Island ; review ; DNA methylation ; genetic polymorphisms ; ecogenetics ; anthropology ; environmental pollutants ; methylmercury ; polycyclic aromatic hydrocarbons ; seafood ; PAH ; PCB ; neritic environment ; seawater ; sediment ; biota ; partition ; contamination ; Ionian Sea ; Tyrrhenian Sea ; database ; meta-analysis ; contaminants ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics ; bic Book Industry Communication::T Technology, engineering, agriculture::TQ Environmental science, engineering & technology::TQK Pollution control
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Agricultural practices, industrial manufacturing, and household consumption are just a few of the activities that contribute to the production of food waste biomass. Modern environmental theories, like the circular economy, are thought to be the impulse behind the implementation of zero-waste policies. The huge percentage of such residual biomass has significant potential to be used as a raw material to produce novel products and specialty feedstock through biorefining procedures, even though the high volume of waste originating from the food industry raises serious concerns regarding both economic and environmental aspects. Given that many plant parts that are rejected during fruit and vegetable processing (e.g., leaves, branches, peels, roots, stems, and seeds) carry a sizable load of phytochemicals, including polyphenols, the recovery of valuable secondary metabolites from waste plant tissues is an appealing prospect in this regard. This specific group of substances exhibits a wide range of chemical compositions with diverse biological characteristics and functions, including antioxidant and antibacterial activities as well as chemoprotective effects against cancer and other degenerative diseases.
    Keywords: oyster shell waste ; washing method ; sodium chloride ; impurities ; particle size ; anaerobic digestion ; agricultural inputs ; biochemical methane potential ; biodegradability ; lignocellulosic biomasses ; manures ; agriculture ; agricultural waste management ; allelopathic effect ; invasive species ; phytoremediation ; rice straw ; rice bran ; rice husk ; agricultural waste ; valorization ; circular economy ; biomass ; bioeconomy ; kinetics ; lignocellulosic biomass ; mechanical pretreatment ; methane potential ; twin-screw extrusion ; fruit and vegetable ; biowaste ; synergies ; matchmaking ; platform ; industrial symbiosis ; waste management ; sustainability ; green building ; recycle ; food waste ; lightweight concrete ; lime concrete ; fruit shells ; coarse aggregate replacement ; sugarcane bagasse ; pentose liquor ; dark fermentation ; biohydrogen ; organic acids ; biorefinery ; fungi ; laccase ; microcosm ; homogenisation ; hemicellulose ; cellulose ; fibre ; conventional limestone ; waste brown eggshells ; polylactic acid ; mechanical properties ; bio-composite ; Aspergillus niger ; ellagitannins ; phenolic compounds ; punica granatum ; saccharomyces cerevisiae ; solid-state fermentation ; limonene ; alpha-pinene ; biotransformation ; terpene ; flavouring agent ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the face of mounting challenges such as food insecurity and environmental degradation, the significance of sustainable agriculture has become increasingly apparent as a beacon for our collective future. Central to this transformative movement is the profound importance of soil health, which serves as the bedrock for both crop productivity and ecological resilience. The Special Issue "Advancements in Soil and Sustainable Agriculture" boldly ventures into this pivotal realm, unveiling a rich tapestry of groundbreaking research dedicated to preserving soil health and cultivating a more environmentally conscious agricultural landscape. Within the pages of this reprint, a wealth of experimental studies and insightful reviews converge to address a broad spectrum of soil sustainability issues. From innovative nutrient management strategies to the remediation of contaminated soils, the contributors to this Special Issue illuminate the nuanced interplay between agricultural practices and the intricate web of soil health. This comprehensive collection stands as a guiding compass for researchers, shedding light on the complexities of sustainable agriculture and paving the way for a future that harmonizes food security with environmental stewardship. The invaluable insights encapsulated within these pages are poised to propel the frontiers of sustainable agriculture, ensuring a trajectory where the principles of environmental consciousness and resilient food production intertwine seamlessly for generations to come.
    Keywords: sustainable agriculture ; soil quality ; best agronomic practices ; soil physical properties ; soil management ; conservation agriculture ; precision agriculture ; cover crop and rotation ; water management ; nutrient management ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Numerous scientific research projects are concerned with improving and protecting the environment. The first steps towards solving the problem of environmental pollution include researching and monitoring the presence and concentration of pollutants, especially heavy metals. It is known from previous studies that fungi bioaccumulate high concentrations of heavy metals, the concentration of which depends, to a greater or lesser extent, on factors such as the species, sampling area, and anatomical parts of the fungus, but also the substrate on which they grow. As the concentration of heavy metals in fungi increases, the importance of fungi as bioindicators of environmental pollution also increases. However, extremely high concentrations of toxic heavy metals in fungi can have negative effects on human health. Constantly monitoring and controlling the levels of metals and metalloids in the human diet is necessary, both in foods of plant and animal origin and in food supplements, or in this case edible mushrooms, whose availability on the market and general popularity are constantly increasing. Therefore, this reprint provides good insights into the development of science and technology in relation to heavy metal concentrations in mushrooms.
    Keywords: bioaccumulation ; mushroom cultivation ; prediction models ; regression analysis ; waste management ; cluster analysis ; health risk ; potentially toxic elements ; mushroom ; spatial analysis ; principal component ; wild edible mushrooms ; metallic elements ; metalloids ; risk assessment ; human health ; organic food ; Boletus griseus ; Hypomyces chrysospermus ; cadmium ; symbiotic association ; health risk assessment ; heavy metals ; health hazard ; mushrooms ; Tricholoma spp. ; copper ; wood ; detoxification ; ligninolytic fungi ; oxalate ; biosorption ; accumulation ; basidiomycete ; bioremediation ; champignon ; common mushroom ; edible mushroom ; sludge ; toxic elements ; wastes ; food quality ; forest biodiversity ; metal elements ; traditional foraging ; wild mushrooms ; mercury ; contamination ; Leccinum ; Y. lipolytica ; CCA-treated wood ; copper stress ; ectomycorrhiza ; morphotype ; metal ; plant ; field ; pot ; inoculation ; Paraisaria dubia ; Zn2+ stress response ; transcriptomic ; metabolomic ; metal ion transport ; microcycle conidiation ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Recent years have seen growing interest in equine lung and heart health, and advances in technology and a focus on equine welfare have driven this research. This Special Issue explores novel diagnostic and therapeutic approaches, including imaging techniques and lung function testing, immunological features, and immunomodulatory treatments for equine asthma and common racehorse respiratory issues. Moreover, it reports on novel echocardiography data of donkeys. This collection offers valuable insights into equine cardio-respiratory medicine.
    Keywords: equine asthma ; exercise-induced pulmonary hemorrhage ; racehorse respiratory medicine ; donkey cardiology ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on treating the associated comorbidities and complications of cerebral palsy. Increased prescription of technology means that we are treating some comorbidities of cerebral palsy earlier or even pre-emptively. Increased life expectancy, compared with 20 years ago, means that we are also seeing even later complications of cerebral palsy. However, increased access to intensive medical care at home, non-invasive ventilation, and total parenteral nutrition now exist. There is also greater engagement with the perspectives and expectations of parents/carers and children. As society begins to discuss mental health more openly, we are also starting to recognise the significant two-way associations between disability and mental health. Ethical consultation may be warranted when harm with treatment exceeds the benefit. As we prepare children with cerebral palsy for adulthood, there is more thought and discussion around issues such as pain, mental health, quality of life, independence, and participation. Researchers in the field of cerebral palsy have contributed original articles and reviews which help build our evidence base to guide shared decision making.
    Keywords: mental health ; anxiety ; depression ; cerebral palsy ; adolescence ; young adults ; young people ; adolescents ; unmet need ; health services ; physical therapy ; occupational therapy ; fracture ; bone fragility ; mortality ; epidemiology ; age-adjusted mortality rates ; death certificate ; medical education ; severe neurological impairment ; scoliosis ; shared decision-making ; respiratory ; hospitalisations ; antibiotics ; Indigenous ; inequities ; cell therapies ; stem cells ; comorbidities ; outcome measures ; clinical studies ; inflammation ; biomarker ; comorbidity ; scoping review ; co-design ; intervention ; participation ; involvement matrix ; public and patient involvement ; early intervention ; infant vocalisations ; infants ; single-subject research design ; CP ; infant ; stress ; parents ; fathers ; parent–infant interaction ; representations ; epilepsy ; children ; neuroimaging ; seizure outcome ; Sialorrhea ; submandibular duct relocation ; postoperative management ; ultrasound ; piecewise model ; muscle volume ; cross-sectional area ; GMFCS ; upper limb ; sensory function ; bimanual intensive functional therapy ; hand function ; associated impairment ; register ; low- and middle-income country ; hip displacement ; hip surveillance ; adductor-psoas release ; hip reconstruction ; guided growth ; salvage surgery ; disability ; emotion regulation ; atropine ; sialorrhea ; pediatric ; drooling ; sublingual ; developmental disorders ; neurodevelopmental disorders ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: With the continuous improvement of people's living standards, the concern for food nutrition and safety has gradually increased. Consumers increasingly need to replace synthetic food additives with natural components extracted from food. Polysaccharides, starch, protein, pectin, and fibre are major types of biopolymer components in foods. They not only provide people with energy and nutrition, but are also used in food processing as natural additives due to their gelling, emulsifying, and film-forming properties, etc. They are characterised by high biocompatibility, low cost, and ease of access. Some natural components isolated from raw food materials have some drawbacks, such as low solubility and instability under certain conditions, which limit their application in food processing. Currently, many researchers are focusing on the modification, food technology, and future industry of polysaccharides, starch, protein, etc. These studies help to obtain the changed physicochemical and enhanced functional properties of these components, and further promote their high-value utilization in the food field. This Special Issue brings together 34 articles regarding the latest advances in the properties of polysaccharides, starch, protein, pectin, and fibre in food processing, from the improvements of the physical properties of major food components and biological activity studies to their applications in food preservation.
    Keywords: polysaccharide ; antibacterial activity ; toxicity ; body health ; gut microbiota ; pre-gelatinization ; thermal properties ; rheology ; structural properties ; microstructure ; starch gel ; polysaccharides ; inflammatory bowel disease ; mechanism ; polyphenol oxidase ; kudzu ; thermostability ; thermal inactivation kinetics ; food constituents ; conformation ; dietary fiber ; fermentation patterns ; cyanidin-3-O-glucoside ; polymeric proanthocyanidin ; degree of polymerization ; starch ; pasting ; retrogradation ; digestibility ; hyperlipidemia ; resistant starch ; Bifidobacterium pseudolongum ; gut microbes ; synbiotics ; hemp protein isolate ; (−)-epigallocatechin gallate ; covalent binding ; structural changes ; emulsifying properties ; polysaccharide-based materials ; edible packaging ; cellulose ; hemicellulose ; chitosan ; polysaccharide gums ; Holothuria leucospilota ; fermentation behaviors ; antioxidant activity ; zein ; flaxseed gum ; ultrasound ; complex particle ; Pickering emulsion ; soybean residue ; insoluble dietary fiber ; fermentation in vitro ; colon health ; pea ; protein co-precipitates ; protein blends ; surface hydrophobicity ; surimi ; setting ; water migration ; chemical interactions ; purslane polysaccharides ; selenylation ; RAW 264.7 macrophages ; splenocytes ; immune modulation ; type 2 diabetes ; β-glucan ; molecular structure ; anti-diabetic function ; macronutrient absorption ; enzyme inhibitor ; ovomucoid ; superheated steam ; modification ; allergenicity ; mass spectrometry ; acrolein ; IEC-6 cells ; autophagy ; apoptosis ; carboxymethyl chitosan ; frozen surimi ; myofibrillar protein ; denaturation ; gelling properties ; walnut protein isolates ; oxidation ; structural characteristics ; functional properties ; proteomics ; collagen peptide ; B16F10 cells ; melanogenesis ; tyrosinase ; antioxidant ; pea fiber ; industry-scale microfluidizer ; structure ; quinoa protein ; ultrasounic-assisted extraction ; in vitro digestion ; amino acid content ; nuclear magnetic resonance hydrogen spectroscopy ; Chinese yam ; structural characterization ; oxidative stress ; okara ; prebiotic ; γ-irradiation ; anthocyanins ; stable system ; inclusion complex ; hydrogen bonding ; biological activity ; packaging ; preservation ; gelatin ; mulberry leaf polysaccharides ; miscible system ; zeta potential ; rheological properties ; betanin ; gelatinization ; camelina cake polysaccharide ; carrier ; stabilizer ; purple corn cob ; by-product ; anthocyanin bioaccessibility ; tapioca ; hygroscopicity ; BET and GAB models ; particle size characteristics ; storage stability ; pea protein ; moderate enzymatic hydrolysis ; structure properties ; dual protein ; plant protein ; co-precipitation dual protein ; blended dual protein ; fish sausage ; pre-emulsion ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint showcases a collection of a Special Issue entitled “Soilless Culture, Growing Media and Horticultural Plants”. Within its pages, readers will find an assortment of 22 original papers accompanied by 1 review paper and 1 editorial. Representing a collaborative effort involving by 84 authors from 15 different countries, this Special Issue explores cutting-edge advancements in soilless culture, investigating the interaction between soilless and environmental factors while also exploring their consequential impacts on plant growth and physiology. Additionally, these studies meticulously scrutinize the accumulation of secondary metabolites. The compositions of nutrient solutions and the physical attributes of substrates and mixtures are illuminated through rigorous analyses. Furthermore, a spotlight is placed on the dynamic interactions between microorganisms and plant-growing media. In the near future, climate change and environmental and ecological issues will steer the trajectory of soilless culture systems and the choice of growing media constituents.
    Keywords: biochar ; compost ; climate change ; hydroponics ; growing medium ; life cycle analysis ; organic bioresources ; peat alternatives ; renewable raw materials ; rockwool ; waste ; wood fibers ; soilless culture ; water soluble fertilizers ; vegetables ; Capsicum annuum L. ; Solanum melongena L. ; nutrients ; shape index ; UVR8 ; PPFD ; dose-dependent ; photosynthesis ; chlorophyll fluorescence ; phenolic compounds ; nutrient uptake ; nutrient variation ; simulation model ; sweet pepper ; restricted deficit irrigation ; soil moisture sensors ; nonchemical growth control ; water use efficiency ; peat ; growth ; cabbage ; Brassica ; emergence ; colored sweet peppers ; antioxidant activity ; phenolics ; ascorbic acid ; carotenoids ; solar and ultraviolet radiation ; peat replacement ; particle size ; calcium ; magnesium ; extractable nutrients ; dry weight ; N levels ; elevated CO2 ; open-top chamber ; nutrient transportation ; transpiration ; dilution effect ; Capsicum annuum ; flavonoids ; fluorescence monitoring ; bio-waste utilization ; NO3–N ; plant ; substrate ; container ; production ; growing media ; nursery production ; carbon ; peat moss ; bioenergy ; Solanum lycopersicum ; olive oil waste ; two-phase ; three-phase ; water sludge ; flower bud development ; flower number ; flower quality ; Gerbera jamesonii ; DLI ; urban agriculture ; simplified soilless culture ; conventional agriculture ; irrigation ; soilless substrates ; water ; coconut coir ; initial moisture ; mass wetness ; peatmoss ; pine bark ; wettability ; capillary rise ; container capacity ; capture rate ; available water ; dewpoint potentiometer ; pine tree substrate ; substrate processing ; surface-bound water ; unavailable water ; wood substrate ; organic and mineral substrates and mixtures ; laboratory characterization ; hydraulic properties ; physicochemical properties ; lettuce ; plant nutrient content ; Pelargonium zonale ; low-tech soilless cultivation system ; commercial quality ; plant growth-promoting rhizobacteria (PGPR) ; rhizosphere ; plant factory ; plant quality ; plant yield ; microbiome ; beneficial bacteria ; germination ; nitrate content ; phenolic content ; antioxidant capacity ; microbial community ; nutrient solution concentration ; sweetpotato ; storage root ; leaf abscission ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The Hsp90 chaperone complex is responsible for the activation and maturation of a vast array of signaling proteins. Recently, there has been a leap in our understanding of the Hsp90 structure and molecular mechanisms involved in such regulation. This has opened a doorway to the underlying mechanisms of disease processes and how we may intervene in such mechanisms to improve prognosis. The focus of this Special Issue is on the recent structural and biochemical advances of Hsp90 that provide insights into the mechanistic activation of Hsp90 on client proteins. It will also include discussions on Hsp90 and its co-chaperones, and their potential as therapeutic targets against human diseases.
    Keywords: Hsp90 ; heat shock proteins ; chaperone ; structure ; mechanism ; regulation ; disease ; cancer ; neurological disease ; drug development ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: We are very excited to introduce this Special Issue of Nutrients, “Advances in Legumes for Human Nutrition”. Recently, legumes have contributed to a sustainable and increased food supply for the rapidly growing global population due to climate change. Legume seeds that are intact or milled into flour offer a complex array of macro- and micronutrients and phytochemicals for human nutrition. Additionally, they can be fractionated into their component proteins, starches, lipids and dietary fibre as health- and techno-functional food ingredients. These ingredients are in great demand by the food industry, for example, in the manufacture of vegetarian and vegan dairy products and meat analogues with good nutritional profiles. However, the issues, such as micronutrient availability, antinutrients and allergenicity, still require solutions for the maximum uptake of legumes by humans. We invited manuscripts that address any aspect of this broad topic, including the impact of innovative food technologies on the nutritional value of legumes and those focusing on nutritional properties of seeds from underutilised members of the Fabaceae (Leguminosae) family.
    Keywords: α-amylase inhibitor ; biofortification ; lectins ; nutritional enhancement ; phytic acid ; predicted glycemic index ; sensory analysis ; temporal dominance sensation ; legumes ; fermented beans ; extruded snacks ; spices ; antioxidant activity ; lupin ; health outcomes ; type 2 diabetes ; cardiovascular disease ; obesity ; legume proteins ; nutraceuticals ; structural properties ; bioactive peptides ; in vivo digestibility ; health effects ; Lupin ; processing ; lupin kernel fibre ; food ingredient ; composition ; techno-functionality ; health benefits ; consumer acceptability ; coronary heart disease ; health care cost ; cost-of-illness analysis ; nutrition economics ; dietary guidelines ; consumption ; sustainability ; chronic disease ; Setaria italica L. ; Cicer arietinum L. ; Hibiscus sabdariffa L. ; chickpea flour ; foxtail millet flour ; minerals ; organic acids ; pregelatinization ; sensory evaluation ; nutritional values ; in vitro bioaccessibility ; benign prostatic hyperplasia (BPH) ; lower urinary tract symptoms (LUTSs) ; voiding symptoms ; soy ; soy food ; isoflavones ; prostate smooth muscle contraction ; faba proteins ; enzymatic hydrolysis ; UHT processing ; emulsion ; phenolic compounds ; in vitro digestion ; colonic fermentation ; cotyledon cells ; in vitro starch digestion ; legume structure ; low glycaemic index ; navy beans ; protein matrix ; beans ; fiber ; pulses ; carbohydrate ; fat ; protein ; NHANES ; waist ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: As the global population and demand for food steadily increase, the maintenance and enhancement of soil productivity to ensure food security is becoming an important issue at the global level as global warming continues to progress. Soil carbon acts as a global carbon sink, playing a crucial role in soil fertility maintenance. Soil carbon is a complex product resulting from various microbial processes; it is a fragile entity, vulnerable to inappropriate human activity and global climate change. Soil microbes that utilize carbon efficiently may help to reduce carbon losses and increase carbon storage. This Special Issue highlights the current understanding of the dynamics of soil carbon and the microbial processes in agricultural ecosystems from the molecular level to the regional and global scales. The topics of interest in this Special Issue include carbon dynamics in plant–soil systems, the carbon balance, approaches to managing soil carbon maintenance and carbon sequestration, and related microbial processes in agricultural ecosystems.
    Keywords: Agriculture ecosystem ; Carbon cycling ; Global warming ; Rhizosphere ; Rhizodeposition ; Soil microbes ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Reprint provides the most relevant and state-of-the-art research in the field, including the use of novel gelation agents, the characterization of the structure and rheological properties of food gels, and the application of food gels in novel food products.
    Keywords: food gels ; novel processing methods ; food applications&nbsp ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint entails descriptions of novel issues and challenges for primary mental healthcare regarding both general and vulnerable populations on a global scale. It is intended for health professionals and all who are interested in mental health care at the primary level.
    Keywords: depression ; sense of coherence ; burnout ; COVID-19 ; nurses ; medication adherence ; mental health nurses ; tacit knowledge ; schizophrenia ; sensory processing sensitivity ; environmental sensitivity ; university students ; nursing ; scale ; somatization ; number of diseases ; coping strategies ; sex ; aggression ; alexithymia ; comprehensibility ; quality of life ; family caregivers ; students ; medical ; psychological problem ; undergraduate ; Saudi Arabia ; n/a ; prospect theory ; applied psychology ; health ; decision making ; behavior ; prevention ; multiple sclerosis ; Beck depression inventory ; anxiety ; fatigue ; mediation ; lawyers ; suicidal ideation ; occupational stress ; loneliness ; perceived stress ; mental health ; work overcommitment ; mental health care ; adolescence ; internalizing/externalizing problems ; social skills ; neurodevelopmental disorders ; filmmaking intervention ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint includes studies on diagnosing, evaluating and managing the pathologies diagnosed during pregnancy. The information provided in these pages is helpful for specialists in obstetrics and gynaecology but also for other medical specialities involved in treating pregnant women with associated pathologies. Studying the articles in the reprint could contribute to improving case management.
    Keywords: pregnancy ; fetus prenatal care ; high-risk ; pathology ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Taking into account the increasing general concern related to the necessity of reducing CO2 emissions, a very important aspect of this topic refers to the green energy sector. In this vein, the present Special Issue is focused on the area of Offshore Renewable Energy (ORE). This Special Issue contains valuable works related to ORE.
    Keywords: Romanian nearshore ; EEZ ; ERA5 ; water depth ; energy resources ; offshore wind turbines ; offshore wind ; technical analysis ; economic analysis ; Philippines ; European seas ; sea state conditions ; wind climate ; wave climate ; statistical analysis ; solar farm siting ; assessment criteria ; entropy weight method ; AHP ; TOPSIS ; wave power ; wave energy converters (WECs) ; Galician coast ; SWAN ; wave-energy converter array ; interconnected model ; model predictive control ; hardware-in-the-loop ; wave energy converter (WEC) ; heaving point-absorber WEC ; WEC array ; WECfarm ; physical modelling ; real-time control ; MATLAB-Simulink ; heaving point absorber WEC ; system identification (SID) ; solar radiation ; marine renewable energy ; floating solar panels (FPV) ; sustainability ; wave energy converter ; floating flapping-panel ; slope ; hydrodynamic performance ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint contains articles published as part of the Special Issue of "Sustainable Tourism: Ways to Counteract the Negative Effects of Overtourism at Tourist Attractions and Destinations" in the journal Sustainability in the "Tourism, Culture, and Heritage" section. It contains 13 articles presenting research on various aspects of overtourism: the attitudes of city dwellers towards overtourism, e.g., Krakow and Wrocław; the effects of tourism development in regions of natural value, e.g., the Tatra National Park; and areas adjacent to tourist routes. It looked at night-time tourism and the sharing economy, as well as how business models can be used to manage sustainable tourism. The phenomenon of overtourism in Tunisia, Brazil, and South Korea is described. The articles published in 2020 are very popular. They have been viewed by several thousand researchers and have been cited 300 times by other authors.
    Keywords: health resorts ; management ; Poland ; investment gaps ; overtourism ; investment attractiveness ; sustainability ; Kraków ; Doxey index ; attitudes ; residents ; service providers ; life form ; dispersal mode ; semi-natural habitats ; trampling ; vascular plants ; tourist experiences ; ecological awareness ; protected areas ; Tatra National Park ; TripAdvisor ; conflict management ; social conflict ; conflict analysis ; circle of conflict ; urban tourism ; tourism-phobia ; tourism in cities ; tourist gentrification ; impact of tourism ; experience economy ; sustainable tourism ; Wrocław city ; subjective well-being ; festivals ; tourism consequences ; tourism area life cycle model ; tourism carrying capacity ; tourism intensity index ; tourism density index ; over-tourism ; temporal distribution ; willingness to pay ; choice experiment ; tourism management and development ; UNESCO World Heritage site ; sustainable development ; Social Capital Theory ; sharing economy ; collaborative economy ; tourism ; gentrification ; tourism impact ; non-mega sports events ; sports tourism ; quality of life of hosts ; social impact of sports events ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the realm of complex decision making, characterized by inherent incompleteness and uncertainty, the foundational work of Lotfi A. Zadeh on fuzzy set theory has been instrumental. The efficacy of classical fuzzy sets in addressing vagueness has prompted an exploration of various extensions, each catering to the intricacies of real-world decision-making problems. This reprint delves into an array of advanced fuzzy theories, including type-2 fuzzy sets, hesitant fuzzy sets, multivalued fuzzy sets, cubic sets, intuitionistic fuzzy sets, Pythagorean fuzzy sets, spherical fuzzy sets, neutrosophic sets, and more. The richness of these extensions reflects the dynamism of fuzzy theories in diverse decision-making applications.
    Keywords: fuzzy theory ; fuzzy decision theory and method ; decision making ; multicriteria decision making ; group decision making ; engineering and scientific applications ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: With the development of modern society, environmental pollution and energy shortages have become the focus of attention worldwide. Most of the global energy supplies are generated from fossil fuel, which gives rise to environmental pollution and climate change. Photocatalysis technology, which can directly convert solar energy into high value-added fuel and chemical materials or degrade a wide range of organic pollutants into easily degradable intermediates or less toxic small molecular substances, is regarded as one of the most important ways to solve the global energy shortage and environmental pollution problem. This Special Issue focuses on advanced photocatalytic materials, including but not limited to photocatalytic materials for the treatment of indoor air, photocatalytic bacterial inactivation, photocatalytic hydrogen evolution, photocatalytic oxygen evolution, photocatalytic CO2 reduction, photocatalytic hazardous pollutant removal, the photothermal decomposition of pollutants, photoelectrochemical water splitting, etc. This Special Issue provides a platform for scientists to present their original research on “Advanced Photocatalytic Materials for Environmental and Energy Applications”.
    Keywords: PbBiO2I microspheres ; CQDs ; ionic liquid ; charge separation ; interface ; polycrystalline silicon ; solar cells ; low-high-low ; phosphorus diffusion ; semiconductor ; photocatalysis ; indoor air treatment ; volatile organic compounds ; microorganism ; photocatalyst ; type-II heterojunction ; carrier separation ; photodegradation ; phase engineering ; water splitting ; CO2 reduction ; pollutant degradation ; MoS2 ; SnS2 ; composite catalyst ; visible light degradation ; thermo-photocatalysis ; nickel foam ; Ni-doped TiO2 ; acetaldehyde decomposition ; zinc oxide ; Langmuir–Hinshelwood–Hougen–Watson model ; methylene blue ; titanium dioxide ; anodization ; self-doping ; cocatalyst ; Mo2C ; phosphorus ; doped ; g-C3N4 ; photocatalytic ; mixture of pollutants ; coupling system ; plasma ; synergetic effect ; mineralization ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint focuses on the geometrical and spectroscopic features as well as potential applications of halogen, chalcogen, pnictogen, tetrel, and triel bonds in chemical reactions, crystal engineering, molecular recognition, and biological systems. We particularly aim to present studies concerning the bonds formed between some novel important electron donors and acceptors, similarities and differences between these bonds, structures of the complexes composed of these bonds in solution and gas phases, spectroscopic methods for measuring these bonds in solution and gas phases, and applications of these bonds in chemical reactions, crystal engineering, molecular recognition, and biological systems.
    Keywords: triel bond ; hydrogen bonding ; proton transfer ; NBO ; halogen bonding ; haloforms ; Amines ; NMR spectroscopy ; UV–Vis spectroscopy ; DFT calculations ; X-ray crystallography ; halogen bond ; QTAIM ; energy density ; pyrazole ; electron density ; hcb net ; metallic anion ; nucleophilic substitution reaction ; quantum chemistry calculation ; reductive elimination ; hydrogen bond ; abnormality ; competition ; AIM ; cysteine dimers ; NCI ; stochastic optimization ; salt bridges ; non-covalent interactions ; dihydrogen bonding ; local vibrational mode analysis ; blue/red shifts ; hydride complexes ; hydrogen storage ; halogen bonds ; density functional theory ; energy decomposition analysis ; ring current analysis ; spin-orbit coupling ; ortho-carborane ; iodo derivatives ; X-ray structure ; I⋯I dihalogen bond ; vinyl cations ; vinyl cation adduct ; very strong H-bond ; proton disolvate ; carborane salt ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The aim of this Special Issue is to specify relevant principles of mathematics and mechanics in order to explore and understand biological problems. We summarize the most important parameters that influence human performance and that are related to the health sciences for all age groups, throughout their lives. We present papers that aim to introduce the latest research in the fields of health, quality-of-life improvement, and sport rehabilitation and that summarize their recommendations for best practice. The aim for this Special Issue is, therefore, to effectively combine and coordinate research and results in order to understand and improve human movement in medicine, sports, and at work.
    Keywords: tendinopathy ; Achilles tendon ; hyaluronic acid ; viscoelastic properties ; isometric contraction ; matrix metalloproteinase 3 ; interleukin-1beta ; fascia ; chronic low back pain ; myofascial release ; quality of life ; older adults ; oldest-old ; measurement invariance ; SHARE European Survey ; therapeutic exercises ; chronic neck pain ; scapular dyskinesia ; DOMS ; vibration ; post-exercise muscle damage ; physical exercise ; recovery ; women’s rugby ; anthropometry ; body composition ; adiposity ; somatotype ; lower-body strength ; accelerometry ; falls ; squat jump ; syndesmosis ; anterior inferior tibiofibular ligament ; high ankle sprain ; rotational instability ; posterior malleolus ; stabilization ; anatomic repair ; syndesmotic screw ; suture-button ; internal bracing ; treatment algorithm ; cardiac rehabilitation ; peripheral artery disease ; COVID-19 ; intermittent claudication ; review ; pressotherapy ; compression ; regeneration ; return-to-play ; rotator cuff repair ; shoulder injuries ; shoulder surgery ; shoulder assessment ; chronic obstructive pulmonary disease ; COPD ; acupuncture ; acupuncture therapy ; acupuncture treatment ; health-related quality of life ; anterior knee laxity ; stiffness ; general joint laxity ; genu recurvatum ; low back pain ; physical activity ; trunk alignment ; rasterstereographic system ; young males ; tissue flossing ; floss band ; vascular occlusion ; muscle strength ; muscle endurance ; warm-up ; TECAR therapy ; high-intensity laser therapy ; manual therapy ; muscle disorders ; hemophilia ; knee ; virtual reality exposure therapy ; joint pain ; physiotherapy ; daily physical function ; middle-aged and older adults ; CHARLS ; aging ; appendicular muscle mass ; inflammaging ; biomarkers ; adiponectin ; sarcopenia ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The 3D analysis of human movement aims to objectively and quantitatively assess motor functions and alterations. It is a valuable method for sport scientists, coaches, and clinicians to evaluate sport performance, common movements, and alterations. The feasibility of 3D analysis is increasing because it can be adopted both in a laboratory setting or directly in the field, in static or dynamic conditions, and for physiological or pathological movements. This evaluation technique can be adopted for many people, including children, adolescents, adults, and older people, whether they are sedentary or athletes and whether they are healthy or motor-impaired people.
    Keywords: virtual reality ; augmented reality ; lifelogging ; mirror world ; health ; posture training ; feedback ; COVID-19 ; neck-shoulder-region ; shoulder protraction ; upper crossed syndrome ; posture weakness ; physical inactivity ; sedentary behavior ; soccer ; climbing ; exhaustion ; fatigue ; training ; machine learning ; sports ; gender ; data mining ; artificial intelligence ; posture ; reproducibility ; mobile app ; movement ; kinesiology ; sport performance ; inertial sensor ; inertial sensor device ; inertial measurement unit ; training load ; external load ; physical demand ; handstand ; postural control ; postural balance ; sEMG ; stabilometric assessment ; exercise ; Nordic walking ; walking ; 3D kinematics ; biomechanics ; gait analysis ; kyphosis ; spinal mouse ; photogrammetry ; postural evaluation ; bicycle ; cyclists ; saddle pressure ; perineal pressure ; urogenital system ; injury prevention ; cervical ROM ; elastic taping ; neck pain ; musculoskeletal health ; n/a ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the orthopedic surgical field, knee surgeries, including articular cartilage repair procedures, meniscus surgery, ligament reconstruction surgery, osteotomy surgery, and partial/total knee arthroplasty surgery, have made great advances over the last few decades. This Special Issue highlights and focuses on the surgical concepts and techniques, decision-making processes, perioperative management protocols, and clinical outcomes of the recent various advanced knee surgery procedures.
    Keywords: high tibial osteotomy ; TomoFix ; plate position ; anatomical conformity ; dual-energy CT ; Hounsfield unit ; bone mineral density ; volumetric phantomless BMD ; opportunistic CT ; orthopedic surgeon ; planning ; survey ; total knee arthroplasty ; unicompartmental knee arthroplasty ; anterior cruciate ligament ; reconstruction ; bone tunnel widening ; adjustable-loop device ; interference screw ; hamstring tendon ; autograft ; tibial component alignment ; radiographic references ; extramedullary system ; tranexamic acid ; clamping time ; transfusion ; estimated blood loss ; continuous cold flow therapy ; cryotherapy ; pain ; opioids consumption ; patient satisfaction ; bone marrow lesion ; knee ; meniscus ; root tear ; root repair ; femorotibial joint ; chondromalacia ; aging ; body mass index ; magnetic resonance imaging ; automated detection ; detection algorithm ; deep learning ; venous thromboembolism ; medial collateral ligament ; strain ; video extensometer ; medial opening-wedge high tibial osteotomy ; central sensitization ; patient-reported outcomes ; osteotomy site pain ; minimal clinically important difference ; human umbilical cord blood derived mesenchymal stem cells ; cartilage regeneration ; cartilage repair ; osteoarthritis treatment ; stem cell therapy ; Outerbridge ; degeneration ; spacer block ; intramedullary rod ; femorotibial congruence ; unicompartmental arthroplasty ; osteoarthritis ; cartilage ; stem cells ; umbilical cord blood ; femur fracture ; polyethylene insert ; osteoporosis ; multivariate logistic analysis ; atelocollagen ; microfracture ; ACIC ; bone marrow aspirate concentrate ; human umbilical cord blood-derived mesenchymal stem cells ; knee osteoarthritis ; loosening ; arthroplasty ; machine learning ; transfer learning ; review ; prosthesis ; meniscus root ; medial meniscus posterior root ; medial meniscus posterior root tear ; meniscus root repair ; transtibial pull-out repair ; bone tunnel enlargement ; anterior cruciate ligament reconstruction ; landmark ; lateral tibial spine ; anatomy ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Over the years, digestive endoscopy has gone through a revolution. With different technological improvements, its diagnostic role is indeed becoming more and more sophisticated and is even moving closer to pathological evaluation. Above all, its therapeutic purpose is to date the first line of treatment for several gastrointestinal diseases. Importantly, the role of digestive endoscopy is also crossing over the mere concept of the GI tract and digestive diseases and will probably find a place in a more holistic concept of health. In this Special Issue, several emerging techniques are addressed, highlighting how endoscopy is emerging as a minimally invasive treatment procedure for several gastrointestinal diseases and post-surgical complications. However, crucial to this is the safety of all endoscopic processes, starting from endoscopic suites to the management of intra- and post-procedural complications.
    Keywords: interventional endoscopy, ERCP, cholangioscopy, biliopancreatic endoscopy, CH-EUS, radiofrequency ablation, necrosectomy, locoregional treatment, bariatric endoscopy, artificial intelligence ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Modern medical imaging systems provide information about the patient's health condition. Their precision, resolution and sensitivity are increasing, and new possibilities of differentiating the condition of tissue are constantly appearing. These advances are also taking place in musculoskeletal imaging. Increasingly accurate imaging in various modalities allows us to discover new relationships between the image and the diagnosis. It is therefore important to use all this information to best serve the patient. That is why research related to the analysis of medical images is so important, because it allows us to indicate what is invisible to the naked eye or to quantify what has so far been measured by humans or subject to discretionary assessment. This collection includes 25 works related to the analysis of images created during diagnostics of the musculoskeletal system using various modalities—from X-ray and fluoroscopy to conventional or spectral computed tomography, magnetic resonance imaging, ultrasound, elastography, PET/CT and systems for analyzing patient mechanics. Research was carried out related to the detection of various conditions, parameterization of clinical and population phenomena, and detection of image–clinical condition relationships. Despite the current popularity of machine learning techniques, the collection is dominated by classic engineering methods related to image processing. Several works use textural analysis, which has not been appreciated so far, which is particularly related to the imaging of the structure, especially of bones.
    Keywords: bone imaging, musculoskeletal imaging, image processing, image analysis, segmentation, textural analysis, machine learning ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue provides an update on the state of the art and current trends in polymeric drug delivery systems specifically designed for improving drug bioavailability. The multiple contributions received further strengthen the role of polymers in modern drug delivery and targeting, illustrating the different approaches possible and unveiling what the future may bring.
    Keywords: Histoplasma capsulatum ; PLGA ; Itraconazole ; macrophage ; functionalized nanoparticle ; F4/80 receptor ; rutin ; nanocrystals ; anti-inflammatory ; hydroxypropyl beta-cyclodextrin ; nanoparticles ; budesonide ; chitosan ; colon delivery ; eudragit ; pellets ; ferrisilicate ; PEG ; insulin ; encapsulation ; diabetic mellitus ; polypeptides ; drug delivery ; doxorubicin ; cancer ; topology of poly-l-cystein ; antimicrobial ; antifouling ; pH sensitivity ; zwitterionic polymers ; gamma radiation ; copolyester ; SPION ; cysteine ; bioconjugation ; and enzymatic release ; polymeric nanoparticles ; drug delivery and targeting ; ocular posterior segment ; oxidative stress ; retinal degeneration ; nerve growth factor ; peanut agglutinin ; zebrafish ; molecular dynamics simulation ; interaction energy ; hydrogen bonding ; solid dispersion ; hot melt extrusion ; amorphous formulation ; tacrolimus ; sucrose acetate isobutyrate ; amorphous solid dispersion ; dissolution ; stability ; pharmacokinetics ; phytomedicine ; nanosponges ; lactoferrin ; bioavailability ; MDA-MB-231 cells ; caspase-3 ; cyclin-D1 ; dendrimers ; Janus nanoparticles ; biocompatibility ; nanoformulation ; pharmaceuticals ; 3D printing ; hybrid scaffold ; polycaprolactone ; vancomycin ; mesenchymal stem cells ; tissue engineering ; drug delivery systems (DDSs) ; osteomyelitis ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Pain biomarkers are biological indicators or measurable characteristics that can provide information about the presence, severity, or underlying mechanisms of pain. They are valuable for several reasons: Diagnosis and differential diagnosis: Biomarkers can help in the diagnosis of various pain conditions and differentiate between different types of pain, such as neuropathic, inflammatory, or nociceptive pain. This can lead to more accurate and timely diagnoses, which in turn can improve patient care. Monitoring treatment efficacy: Pain biomarkers can be used to track how well treatments are working for individuals suffering from chronic pain conditions. This allows healthcare providers to make informed decisions about adjusting treatment plans, optimizing pain management, and avoiding unnecessary or ineffective interventions. Drug development and testing: Biomarkers play a crucial role in the development of new pain medications and therapies. They can help researchers identify potential drug targets, screen compounds for their pain-relieving properties, and assess the safety and efficacy of experimental treatments in clinical trials. Personalized medicine: Pain biomarkers may, in a future, contribute to treatments, tailored to an individual's unique genetic and biological disposition. Reducing opioid misuse: By using biomarkers to assess pain and treatment responses, healthcare providers can make more informed decisions about opioid prescriptions, potentially reducing the overuse and abuse of these medications.
    Keywords: analgesia ; biomarker ; CSF ; cytokine ; inflammation ; neuropathy ; neurotransmitter ; pain ; QoL ; sensitization ; sensory ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on the comprehensive understanding and novel treatments in the realm of cornea and ocular surface diseases. Ranging from the relatively benign manifestations of keratoconjunctivitis sicca to more critical conditions such as corneal ulcers, ocular surface diseases pose a considerable challenge in clinical ophthalmology. Such conditions can severely compromise the transparency of the cornea, often necessitating interventions such as keratoplasty. A significant emphasis of this edition is on the paramount importance of pre-surgical optimization. A successful keratoplasty is often predicated on the health of the ocular surface. Through a series of insightful articles, the importance of enhancing tear function, rehabilitating the normal lid anatomy, and ensuring a robust limbal stem cell supply is elucidated. Properly addressing these factors has a direct bearing on the success rate of the subsequent surgical intervention. Another highlight of this Special Issue is the presentation of cutting-edge treatments. Researchers from around the globe share their findings, detailing advancements in both surgical and non-surgical treatments. These range from innovative surgical techniques and tools to groundbreaking pharmaceutical agents that hold promise in managing and possibly reversing some of these conditions. In summary, this Special Issue serves as a repository of the latest knowledge in the management of cornea and ocular surface diseases, aimed at both the seasoned ophthalmologist and budding researchers in the field.
    Keywords: cornea ; ocular surface disease ; dry eye ; corneal ulcer ; keratoplasty ; bic Book Industry Communication::M Medicine
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  • 53
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint includes 23 research articles and 1 review accepted and published by MDPI in the Special Issue entitled "Recent Advances and Applications in Partial Least Squares Structural Equation Modeling (PLS-SEM)", comprising 7 articles in Economies, 6 articles in Mathematics, 10 articles in Sustainability and 1 article in Data. The covered topics include the impacts of COVID-19 and climate change on food security or the tourism sector, the critical factors affecting the implementation of corporate governance, consumers' perspectives and behaviors toward corporate social responsibility, consumers’ ethnocentrism and country of origin, the differentiation strategy and export performance in emerging countries, the influence of agricultural development on alleviating rural poverty, leadership and employee performance, the relationship between entrepreneurial orientation and business performance, the role of commitment in an extended theory of planned behavior, major shifts in sustainable consumer behavior, an empirical evaluation of customers' adoption of drone food delivery services, European citizens' happiness, the mediation of corporate social responsibility between information and communication technologies adoption and SMEs performance, students’ satisfaction about blended learning, etc. This reprint is expected to benefit those working in the area of PLS-SEM, regardless of their field of study (economics, finance, marketing, education, etc.). Applications involving higher-order constructs, mediating variables, multigroup analysis, and the latest advances in applied methodology are detailed in this reprint.
    Keywords: PLS-SEM ; structural equations ; economics ; finance ; healthcare ; sustainability ; environment ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Soilless Culture Systems (SCSs) have expanded globally into protected and open-field horticulture. However, it is crucial to ensure the sustainability of this system in order to address resource challenges, minimize environmental impacts and establish a resilient and efficient agricultural system in the face of global challenges. This Special Issue reprint emphasizes the significance of transitioning to sustainable horticultural practices, outlines the challenges encountered, and presents various strategies to reduce or eliminate the utilization of peat in growing media. Additionally, it introduces cascade systems strategies that include recycling nutrient solutions, minimizing pesticide emissions, and integrating eco-friendly practices. Utilizing microorganisms has been identified as a potential strategy to augment the resilience of plants against the onslaught of pests and diseases. This approach is expected to reduce the utilization of chemicals for the same purpose considerably. This Special Issue reprint significantly contributes to advancing sustainable SCSs and growing media, providing diverse strategies and insights in order to propel its progress as a viable form of sustainable agriculture. It comprises 11 original contributions and an editorial written by 45 authors from 10 different countries. These numbers differ slightly from what was reported in the Editorial, as the Editorial was written before the last article was published.
    Keywords: Soilless culture ; growing media ; peat alternatives ; cascade systems ; bio-fertilizers&nbsp ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This textbook “Applied Mathematics in Ferroelectricity and Piezoelectricity” was authored to provide the reader solid mathematical background for studying “ferroelectricity and piezoelectricity”, as a supplemental reference to my three course books; “Ferroelectric Devices 2nd Edition (2010)”, “Micromechatronics 2nd Edition (2019)”, and “FEM and Micromechatronics with ATILA Software (2008)”, all published from CRC Press. “Physics” prefers “simplicity”; converting a complicated phenomenon expressed by a function.
    Keywords: ferroelectrics ; piezoelectricity ; phenomenology ; applied mathematics ; bic Book Industry Communication::T Technology, engineering, agriculture::TB Technology: general issues ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The effort of the Editors has received global attention. Indebtedness is due to Saha and Asif and coworkers from Canada, Joseph and Mahapatra and coworkers from Poland and India, Ramirez-Montoya and coworkers from Spain and Mexico, Mota-Panizio and coworkers from Portugal and Brazil, Izquierdo and Lopez-Coca and coworkers from Spain, Vinitnantharat and coworkers from Thailand and the UK, Roy and Fini and coworkers from India and the USA, Lawson and Luyima and coworkers from Ghana and South Korea, Fouad El Mansouri and coworkers from Morocco and Spain, and Man Zhang and Yaning Zhang and coworkers from China for the 10 scholarly research papers dealing with the synthesis, characterization, properties, and applications of new carbon materials. The applications are mainly centered around environmental remediation owing to the intensity of the problem and comprise of water decontamination and the removal of heavy metals and organic compounds like tannic acid from contaminated sources. The use of biochar in agriculture for preventing nitrogen leaching for soil has also been included. Unconventional carbon-related materials like rice husk ash and carbon steel slag were also used for exotic applications.
    Keywords: polymers ; biocompatible ; biodegradable ; compostable ; sustainable ; market dynamics ; research trends ; graphene ; graphene-like materials ; carbon ; biomass pyrolysis ; microwave pyrolysis ; OMWW ; adsorption ; carbon steel slag ; tannic acid ; biochar ; dry matter accumulation ; leaching of nitrogen ; nitrogen uptake ; tropical sandy soils ; sustainability ; carbon footprint ; rice husk ash ; lime ; silica ; asphalt ; concrete ; roadways ; fractionation ; heavy metal removal ; isotherm ; modified biochar ; WIEC ; carbonization ; pretreatment ; activation ; carbonaceous material ; hydrothermal carbon ; Castanea sativa ; biomass residues ; residue valorization ; per- and poly-fluoroalkyl substances (PFAS) ; water decontamination ; porous carbon monolith ; whey ; biomass carbon ; mechanical properties ; C ; H ; N ; corn straw ; microwave heating ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNK Inorganic chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Although they play a key role in ecosystem functioning and human life, plants are generally overlooked by policymakers and humans in general. In addition, in recent years, we have been witnessing an increase in biologists unable to recognize even common plants, and the number of plant experts (i.e., botanists) able to identify plants is decreasing. In light of these considerations, the Special Issue "Floristic Studies in the Light of Biodiversity Knowledge and Conservation” was launched in the journal Plants, and eight research articles, two reviews, and an editorial were published in it. It has been possible to publish research from different countries, underlining that the knowledge of the flora of a territory is essential to slow down the effects of anthropic pressure on biodiversity and likewise essential for most of the research activities of modern botany.
    Keywords: correlation ; ecology ; essential oils ; Lamiaceae ; vegetation ; species composition ; richness ; urban areas ; anthropogenic impact ; climate ; anthropogenic habitats ; Caucasus ; Himantoglossum formosum ; human-made habitats ; Orchidaceae ; salep harvesting ; Transcaucasia ; kapok ; Ceiba ; fiber ; sustainability ; Malvaceae ; silk-cotton ; phenotypic plasticity ; mangrove grass ; salt marshes ; coastal habitat ; biodiversity ; bryophytes ; generalist plants ; grassland specialists ; historical monuments ; invasive alien plants ; kurgans ; lichens ; native plants ; alien status ; biological records ; Europe ; Latium ; Mediterranean flora ; Rome ; urban biodiversity ; endemism ; floristic research ; herbaria ; lectotype ; nomenclature ; taxonomy ; halophytes ; edible wild species ; coastal areas ; Salicornia ; Arthrocaulon macrostachyum ; Soda inermis ; Cakile maritima ; Crithmum maritimum ; Reichardia picroides ; Silene vulgaris subsp. tenoreana ; Allium commutatum ; Beta vulgaris subsp. maritima ; Capparis spinosa ; Italy ; IUCN ; morphology ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PST Botany & plant sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The Special Issue "Numerical Heat Transfer and Fluid Flow 2022" contains scientific articles on experiments and simulations of heat transfer in compressible and incompressible fluids, including single- and two-phase flows. The articles present the current state of knowledge, solve scientific and industrial problems, and set directions for future research. The Special Issue is addressed to specialists from around the world dealing with numerical modelling and experiments on heat transfer in flowing fluids.
    Keywords: heat transfer ; fluid flow ; experiments, simulation and modelling of fluid flow ; compressible and incompressible flow ; single- and two-phase flow. ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Cancer is one of the leading causes of morbidity and mortality in humans today, and the number of people affected by cancer is growing. As a result, the search for new antitumor agents that may be more effective and secure than existing treatments is an ongoing effort. Nature provides a wide range of compounds with a great variety of chemical scaffolds and distinct bioactivity profiles. Indeed, natural products are a rich source of bioactive molecules that, over the years, have found application in the treatment of many diseases, including cancer. Natural products have played an important role in chemotherapy and chemoprevention by providing antitumor drugs such as camptothecin, doxorubicin, paclitaxel, vinblastine, and vincristine, as well as understanding the cellular and molecular mechanisms underlying antitumor activity. Significant advances in natural source isolation and extraction techniques have enabled the identification of novel lead compounds as useful starting points for the generation of optimized molecules with enhanced therapeutic potential via semi-synthetic or synthetic processes. The focus of this Topic is on natural substances derived from plants or animals, as well as their synthetic derivatives, which have been investigated for their ability to counteract cancer progression.
    Keywords: natural compounds ; natural derivatives ; anticancer ; drug discovery ; antiproliferation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint delves into the latest advancements in aquaculture techniques emerging from China. It provides a comprehensive update on the research and technological developments in various aspects of aquaculture, including biotechnology, ecotechnology, feeding technology, and environmental technology. The reprint covers a wide range of topics, such as the use of biotechnology to identify and characterize genes that enhance resistance to bacterial infection and environmental stress. It also explores feeding technology that improves immunity and stress resistance in aquatic organisms. Additionally, the reprint discusses the detection of the impact of thermal stress on marine fish immunity, the manipulation of light color to enhance algal growth, and the utilization of integrated multi-trophic systems to boost production. With a focus on marine fish, shrimp, sea cucumbers, sea urchins, and algae, this reprint showcases groundbreaking research that paves the way for future advancements in aquaculture. These innovative technologies are expected to have far-reaching implications for other species in the field of aquaculture.
    Keywords: aquaculture ; biology ; biotechnology ; environment ; &nbsp ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAF Fisheries & related industries
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    Publication Date: 2024-01-08
    Description: This reprint, entitled “Management of Acute and Chronic Complications of Lysosomal Storage Diseases in Children and Adults: Current Practice and Future Opportunities”, covers broad aspects of this group of rare diseases. The first theme includes articles on the management of pain, corneal clouding, gastrointestinal and airway diseases in Mucopolysaccharidoses and Mucolipidoses, and the evaluation of dysphonia in Pompe disease. Additionally, attention deficit and ADHD and the management of atherosclerosis in Fabry disease are considered here. The second theme includes diagnostic conundrums in lysosomal storage diseases, e.g., the prenatal diagnosis of Gaucher disease during pregnancy, the diagnosis of secondary hyperparathyroidism in Mucolipidoses, and the application of the new biomarker “plasma neurofilament light” in Niemann Pick C disease, as well as the correlation of enzyme activity with molecular diagnosis in Pompe disease. The articles in the third theme describe the impact of therapies on clinical outcomes. For example, a systematic review of the impact of enzyme replacement therapy on late-onset Pompe disease and trehalose use on Niemann Pick A and B is included. The remaining articles describe the NHS processes for overcoming challenges resulting from the COVID-19 pandemic and the differences in the transition from paediatric to adult services between different countries.
    Keywords: Mucopolysaccharidosis ; corneal clouding ; penetrating keratoplasty ; deep anterior lamellar keratoplasty ; mucopolysaccharidoses ; airway ; obstruction ; management ; Fabry disease ; attention ; Attention Deficit/Hyperactivity ; cognition ; late-onset Pompe disease ; gastrointestinal ; smooth muscles ; PROMIS–GI symptom scales ; GAAKO mice ; glycogen storage disorder ; translational research ; patient-reported outcomes measures ; mucopolysaccharidosis ; MPS ; disease manifestations ; symptoms ; morbidity ; spine disease ; anaesthesia ; perioperative complications ; surgery ; pompe disease ; speech ; voice ; dysphonia ; acoustic ; auditory-perceptual ; GRBAS ; respiratory ; Pompe disease ; gene panel sequencing ; alpha-glucosidase ; GAA ; dried-blood spots ; fabry disease ; neuropathic pain ; depression ; Fabry ; atherosclerosis ; ischaemia ; perfusion ; angina ; Sanfilippo syndrome ; mortality ; Niemann–Pick C ; neurofilament light ; biomarkers ; neurological disease ; glycogen storage disease type II ; enzyme replacement therapy ; COVID-19 ; inherited metabolic disorders ; rare autoinflammatory diseases ; health care providers ; Gaucher disease ; NIHF ; perinatal-lethal Gaucher disease ; PLGD ; ichthyosis ; GBA gene ; airway management ; radiology ; hyoid bone ; chin ; intubation ; intratracheal ; lysosomal storage disease (LSD) ; Niemann–Pick type A ; Niemann–Pick type B ; acid sphingomyelinase ; sphingolipid deposition ; trehalose ; mucolipidosis type II ; ML II ; I-cell disease ; hyperparathyroidism ; mucolipidosis ; ML ; MLII ; transition service ; adult metabolic medicine ; collaboration ; challenges ; inherited metabolic diseases ; healthcare systems ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Molecular toxicology is a field that investigates the interactions between chemical or biological molecules and organisms at the molecular level. In this Special Issue, we focus on the toxic effects and mechanisms of action of chemical and biological molecules, will be of great interest of readers in molecular toxicology and applied pharmacology.
    Keywords: smoking ; inflammatory ; cytokine ; human serum ; GO ; PRRSV ; FT-SPR ; sensitization ; NNK ; nicotine ; cytotoxicity ; genotoxicity ; cytochrome P450 2A13 ; Aspergillus flavus ; aflatoxins B1 ; carcinogen ; Surface-Enhanced Raman Scattering ; colloidal Au nanoparticles ; portable Raman spectrometer ; Euphorbia semen ; Euphorbia factors ; transcriptome ; RNA sequencing ; bioinformatics ; gene structure ; neuroblast differentiation-associated protein AHNAK ; hepatocellular carcinoma (HCC) ; insulin-like growth factor 1 receptor (IGF-1R) ; interactome ; field cancerization ; 8–17 DNAzyme ; gene silencing ; catalysis ; antisense ; chemical modifications ; 6-cyclohexyl methyl-β-D-maltoside ; transduction efficiency ; conditionally replicative adenovirus ; lethal effect ; gene therapy ; PBDE ; immunotoxicity ; macrophage ; reactive oxygen species ; apoptosis ; immune function ; breast cancer ; signature ; aging ; cancer ; nomogram ; immunotherapy ; tumor mutation burden ; doxorubicin ; Toll-like receptor 4 ; cardiotoxicity ; heart ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology::MMGT Medical toxicology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the current context of global change and global interconnectedness, our role in connecting the dots and finding solutions to current and future problems is very important. When talking specifically about the management of forests, we can see its continuous evolution and, more importantly, its adaptation to contemporary challenges. As is well known, forest ecosystems play an essential role in our economy, human wellbeing and global wellbeing. More specifically, one of the main challenges in forest management is represented by the sustainability of resources and need to conserve biological diversity. The best way is to think globally, to find patterns that repeat themselves and to investigate solutions that can help us to prepare a better future. In this regard, we think that it is essential to review papers that present interesting findings that could guide us. The first step was to select 18 articles from a wide range of countries located on three continents, including Brazil, Bulgaria, Ecuador, Germany, Malaysia, Peru, Poland, Romania, Slovakia, and Slovenia. Our main goal was to analyse the regionally specific aspects, as well as general aspects that can be applied worldwide. Using this approach, we narrowed our research to eight sub-domains: natural and human disturbances, genetics, site conditions, tropical forest, peri-urban forest, forest soils, forest reserves, and mountain ecosystems. These articles tackle themes such as peri-urban forests and their impact on urban agglomerations, ecoturism, cultural heritages and practices from local communities, human interventions and best practices.
    Keywords: BDq method ; Eastern Amazon ; degraded tropical forest ; forest restoration ; forest economy ; logging selection criteria ; sustainable forest management ; visual perception ; rainforest ; land use ; aesthetics ; Amazon ; management implications ; black locust ; forest ; germination ; provenances ; seed dormancy ; old growth forests ; gene flow ; molecular markers ; legally protected forests ; noninvasive genetic sampling ; brown bear ; management plan ; residual trees ; logging technology ; silvicultural works ; tree healed wound ; forest gaps ; plant colonisation ; community strategy ; Dinaric fir-beech forests ; Ellenberg values ; whole system approach ; data fusion and integration ; semantic and ontological compatibility ; mountain ecosystems ; ecosystem condition ; remote sensing ; vegetation indices ; climate change reanalysis ; dominant species level forest ecosystem classification ; Norway spruce ; Douglas fir ; beech ; maple ; soil chemical properties ; soil microorganisms ; silver fir ; Romanian Carpathians ; stand productivity ; forest sustainability ; silviculture ; ecology ; management ; risks ; uses ; impact ; competitive strength ; forest management ; nature conservation ; naturalness ; European beech ; species diversity ; invasiveness ; homogenization ; Ophiostoma novo-ulmi ; subspecies ; Ulmus minor ; U. glabra ; U. laevis ; tolerance to DED ; climate ; built-up area ; geographical information systems (GIS) ; native species ; plant diversity ; urbanization gradient ; ecological reconstruction ; bacteria diversity ; sustainable rehabilitation ; climate change effects ; peri-urban forest management ; forest stability ; urban expansion ; greenhouse gas emissions ; forest resilience ; diversity ; four corner ; microscale elevation ; correlation ; elevation effects ; alpha diversity ; Andes ; tourist circuit ; beta diversity ; native plants ; phenology ; species richness ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KNA Primary industries::KNAL Forestry & related industries
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The prevalence rates of risk factors for premature mortality and early non-communicable diseases are growing due to the increasing prevalence of poor nutrition habits, increasing levels of stress, and sedentary lifestyles. The life course epidemiology offers an integrative approach which guides research on health, human development, and ageing. The translation of this life course approach to women’s health is indispensable. It comprises the investigation of risk factors across the life that influence the timing of menarche, fertility, pregnancy outcomes, gynaecological disorders, and age at menopause. It also recognises the important influence of reproductive health on later non-communicable disease risks. The continuity of reproductive health and the relationship between different biomarkers and risk factors are taken into account in this integrative approach. Within women’s life courses, lifestyle plays an essential role, ranging from young age to pregnancy, menopause, and healthy aging. The underlying mechanisms and the effect sizes between nutrition and many diseases are only partly known due to the often multifactorial disease processes. The link between lifestyle and the growing rates of different diseases (e.g., cervical, ovarian carcinoma, breast cancer, cardiovascular diseases, or diabetes mellitus) needs to be investigated further. New scientific approaches are being used to try to relate individual biomarkers to dietary patterns and changes in the microbiome in order to make risk potentials visible earlier. The collection of scientific contributions on nutrition and women’s health is presented here.
    Keywords: dietary factors ; nutrition ; women health ; specific diseases ; gynaecologic diseases ; non-communicable diseases ; life course epidemiology ; pregnancy ; menopause ; prevention ; &nbsp ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint aims to identify critical areas of water quality assessment, modeling, and mitigation in freshwater bodies, wastewater treatment, and groundwater aquifers, which require special attention. This links the volume to multiple regulatory options, including policy and governance measures, alternative ecosystem service dependence options (i.e., nature-based solutions), or mechanisms that link regions to international processes, like measures proposed under the Environmental Protection guidelines. The reprint will pay special attention to water quality assessment, modeling, and mitigation.
    Keywords: pumping station pipeline ; chaotic characteristic ; IVMD ; vibration response ; correlation dimension ; Lyapunov exponent ; monitoring ; mitigations ; spatial and temporal variabilities ; principal component analysis ; cluster analysis ; discriminant analysis ; water quality ; pollution ; correlation ; settlement ; damage evolution ; seepage/stress-damage method ; data monitoring ; groundwater ; heavy metals ; physicochemical parameters ; in-situ ; machine learning ; geostatistical analysis ; nanofiltration ; electrocoagulation ; nickel ; zinc ; copper ; water pollution ; adsorption ; copper ions ; adsorption mechanism ; adsorption kinetics ; thermodynamics ; expanded S-curve model ; domestic water usage ; economic development ; mathematical model ; Sentinel-2 ; chlorophyll ; turbidity ; lake ; concentration modeling of contaminants ; Cuernavaca aquifer ; hydrochemistry ; water quality index ; time series analysis ; spatial analysis ; water intensity ; LMDI model ; Tapio model ; technical effect ; industrial structure effect ; regional scale effect ; tannery effluent ; ozonation ; optimization ; turbidity removal ; Taguchi ; ecosystem services ; provisioning ecosystem services ; regulating ecosystem services ; cultural ecosystem services ; supporting ecosystem services ; modeling ; water quality indexing ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Partial differential equations are indispensable for modeling various phenomena and processes, such as those in physics, biology, finance, and engineering. Finding solutions to partial differential equations using qualitative theories or quantitative methods, as well as the application of such investigations to real-world problems, has drawn a large amount of interest from researchers. This reprint encompasses all the articles that were accepted and published in this Special Issue titled "Applications of Partial Differential Equations ". We hope that these accepted and published papers will be impactful and motivate future research on partial differential equations for solving complex problems in various fields, disciplines, and applications.
    Keywords: non-linear optimal control ; stratified fluids ; energy functional ; optimal condition ; state variable ; travelling waves ; Eyring–Powell ; geometric perturbation ; nonlinear reaction–diffusion ; unsteady flow ; C∞-semigroups ; analytic semigroups ; Fourier multipliers ; Λ-ellipticity ; fractional Zakharov system ; stochastic Zakharov system ; Riccati–Bernoulli sub-ODE method ; Jacobi elliptic function method ; generalized fractional derivative ; time-diffusion problem ; generalized linear interpolation ; numerical scheme ; backward nonlocal wave equation ; Pascal bases automatically satisfying specified conditions ; integral boundary condition ; nonlocal boundary shape function ; delay differential equations ; 2D parabolic equations ; fractional step method ; convection diffusion problems ; shallow water flow ; Faedo–Galerkin method ; feedback control ; PDE’s stabilization ; tuberculosis ; COVID-19 ; diffusion ; coinfection ; stability ; singularly perturbed problem ; parabolic differential equation ; convection–diffusion problem ; line discontinuous source term ; streamline–diffusion finite element method ; Shishkin mesh ; uniformly convergent ; diffusion equations ; traveling waves ; phototaxis ; bacterial motion ; biological aggregation ; chemotaxis model ; integral inequality ; global uniform boundedness ; CNL-GZE ; lump-type solitons ; rogue wave ; appropriate transformation technique ; optimal decay ; viscoelastic wave equation ; nonlinear time-varying delay ; nonlinear damping ; acoustic boundary conditions ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, we have gathered high-level research papers from all over the world. We would like to thank all researchers for their commitment to the field. From diagnostic ultrasound of different fetal conditions to advanced cardiovascular imaging leading to fetal MRI and from serum markers and biomarkers in maternal and fetal conditions to new modalities in fetal therapy, this Special Issue covers a large scale view of the present spectrum of modern perinatal medicine. Again, a warm thank you to all contributors.
    Keywords: fetal echocardiography ; fetal abnormalities ; fetal therapy ; genetic testing, prenatal medicine ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Drought and climate change have decreased water availability for agriculture in arid and semiarid regions, and therefore efficiency enhancements in irrigation water management aimed at conserving water are key to adjust to limits in water supply, as well as improve the profitability and sustainability of agricultural production. Agricultural water management tools and practices that reduce water uses with acceptable impacts on crop production are viable strategies required to cope with diminished water supplies and generate new sources of irrigation water. This Special Issue focuses on “Agricultural Water Conservation: Tools, Strategies, and Practices”, which aims to bring together a collection of recent cutting-edge research and advancements in applied agricultural water conservation. It provides a broad overview focusing on irrigation decision support systems, drought management plans, deficit irrigation strategies, soil mulching, surface and subsurface drip irrigation, conservation tillage, and optimal water and fertilizer management practices.
    Keywords: drought stress ; protein content ; rainfed ; yield stability ; wheat ; water quality ; agro-ecological wetland ; irrigation ; nutrients ; ecological status ; drought ; water scarcity ; risk-based approach ; drought management plan ; assessment protocol ; river basin scale ; rice ; water footprint ; nutrient use efficiency ; productivity ; profitability ; benefit-cost ratio ; physiological traits ; rainwater harvesting system ; rain-fed conditions and ridge-furrow mulching ; correlation ; environment ; humic acid ; PCA analysis ; rain-fed ; wheat varieties ; mulching ; spearmint ; yield ; ecophysiology ; essential oil ; hydrogel ; irrigation deficit ; mandarin ; proline ; irrigation emitter ; hydraulic performance ; energy dissipation mechanism ; structural design ; computational fluid dynamics ; food–water–energy nexus ; nitrate leaching ; precision agriculture ; water productivity ; irrigation management ; soil moisture ; potato fertigation ; leaf area index ; root mass density ; real water productivity ; field water balance ; subsurface pipe drainage ; soil salinity ; saline groundwater ; winter wheat ; numerical simulation ; cowpea ; deficit irrigation ; zinc ; amino acid ; biofortification ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Oral cancer is a commonly occurring head and neck cancer, with 90% of cases diagnosed as oral squamous cell carcinoma (OSCC). Histologically, OSCC is derived from a multistep mechanism known as oral carcinogenesis, which progresses from normal epithelium to hyperplasia, followed by dysplasia and carcinoma in situ, and precedes the development of invasive squamous cell carcinoma. This multistep mechanism is characterized by mutations related to copy number alteration and epigenetic modifications. Precision medicine based on genomic profiling is also becoming more prevalent. It relies on the genetic information of individual patients or specific cancer cells and how their genes interact with each other and the environment. This method can potentially provide more effective treatment strategies as approaches can be customized for the specific genetic profiles of patients. Completing the TCGA HNSCC database has led to the development of new therapeutic approaches and targeted therapies. Lately, immune checkpoint inhibitors have been recognized as one of the standards of care in HNSCC. However, although treating invasive SCC is crucial, implementing prevention strategies to preclude malignant transformation has been useful in clinical management. Topics of interest for this Special Issue include, but are not limited to: Precision medicine, i.e., targeted therapies that inhibit oral carcinogenesis and tumorigenesis mechanisms; Combination of novel therapeutic approaches with standard-of-care regimens in OSCC; Biomarkers, i.e., predictive and prognostic markers for therapeutic approaches.
    Keywords: oral carcinogenesis ; oral tumorigenesis ; oral squamous cell carcinoma ; immune checkpoint inhibitor ; mutation ; biomarkers ; chemoradiation ; targeted therapies ; cisplatin ; preclinical models ; deep learning ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue includes ten papers by 45 authors, including excellent cutting-edge research from Japan. Looking at the papers reported here, Japan’s liquid crystalline research is a global pioneer within this field. It is clear that Japanese liquid crystalline research will further develop in the future.
    Keywords: white emission ; liquid crystal ; aggregated structure ; gold(I) complex ; carbazole moiety ; molecular chirality ; π-conjugated compound ; chromonic liquid crystal ; ionic liquid ; nematic ; hexagonal columnar phase ; twist–bend nematic phase ; direct twist–bend nematic phase transition ; liquid crystal dimer ; cyanobiphenyl dimer ; short spacer ; diphenylacetylene ; fluorinated tolanecarboxylic acid ; fluorine ; photoluminescence ; liquid crystals ; nematic phase ; phase transition ; polysiloxane ; photoalignment ; UV curing ; rubbing method ; composite alignment layer ; high pretilt angle ; incidence angle dependence ; mechanofluorochromic dye ; gel ; electrochromism ; tetrafluorocyclohexa-1,3-diene ; tricyclic molecule ; aggregation ; self-sort ; segregated columns ; binary mixture ; amphiphilicity ; homeotropic alignment ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry ; bic Book Industry Communication::P Mathematics & science::PN Chemistry::PNR Physical chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The agricultural sector is undergoing a profound transformation derived from the introduction of new technologies and tools from industry 4.0, giving rise to what has been called Agriculture 4.0. This Reprint contains a selection of some interesting recent advances in this field, including new techniques for remote crop sensing and agricultural machinery, the development of novel vision and deep learning algorithms, advances in aquaculture technologies, and a review on the state of the art in Horticulture 4.0.
    Keywords: Agricultural engineering ; new technologies ; remote sensing ; precision agriculture ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::T Technology, engineering, agriculture
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The topics covered in this Special Issue range from breastfeeding and early-life nutrition to effects on microbiota, infection, allergy, asthma, and the mechanisms of immunomodulation via (the early introduction of) nutrition on infections and the development of (food) allergies.
    Keywords: diet ; pregnancy ; cord blood ; fatty acids ; n-3 PUFAs ; n-6 PUFAs ; arachidonic acid ; phospholipids ; atopic eczema ; NICE birth cohort ; multi-allergen ; early introduction ; food allergy ; safety ; efficacy ; prevention ; allergic sensitization ; foetal immune ontogeny ; gene/environment interactions ; asthma ; eczema ; maternal diet ; PUFAs ; vitamin D ; Mediterranean diet ; microbiome ; breastfeeding ; functional gastrointestinal disorder ; partial hydrolysate ; peptide ; protein ; infancy ; childhood ; immune development ; probiotic ; microbiota ; allergy ; atopic dermatitis ; breastmilk ; house dust mite ; Der p 1 ; Asthma ; total IgE ; atopy ; sensitization ; oral tolerance ; early food introduction ; milk protein ; cow’s milk allergy (CMA) ; maternal atopy ; epigenetics ; pediatric asthma ; cohort study ; immune complex ; trained immunity ; RSV ; bovine IgG ; preF protein ; cow’s milk allergy ; allergen ; hypoallergenic infant formula ; n/a ; IgA deficiency ; selenium deficiency ; zinc deficiency ; recommended dietary allowances ; immune system ; allergen molecules ; milk allergen micro-array ; peptides ; anaphylaxis ; milk tolerance ; diagnosis ; IgE sensitization ; children ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This comprehensive reprint explores the remarkable advancements in energy-related systems driven by the utilization of nanomaterials. It covers a wide range of topics, from material-level investigations to device-level applications, incorporating molecular dynamic simulations and measurements of electrical, thermal, dielectric, and electrochemical properties. The chapters delve into optimizing heat transfer processes, enhancing HVAC systems, improving Li-ion battery performance, developing high-performance carbon nanofiber anodes, and exploring the potential of flexible porous silicon/carbon fiber anodes. The reprint also discusses formic acid microfluidic fuel cells, 2D MXenes, electrical breakdown models, nanocomposite capacitors, and the dielectric behavior of nanofluids. It addresses topics such as radical scavenger fillers, the thermal properties of ternary nitrate, distributed Bragg reflectors, Pd–Pt bimetallic dendrites, and the oil–water interface behavior of modified graphene oxide. With its multidisciplinary approach and comprehensive coverage, this reprint serves as a valuable resource for researchers, scientists, and engineers working in the field of energy-related systems and nanotechnology.
    Keywords: nanocomposites ; nanofluids ; electrochemical synthesis ; electrochemical energy conversion and storage ; lithium-ion batteries ; capacitors ; light-emitting devices ; fuel cells ; heat transfer fluids ; electrical breakdown ; dielectric properties ; specific heat capacity ; thermal diffusion coefficient ; molecular dynamics simulation ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This compilation of scientific work delves into innovative wastewater treatment technologies, focusing primarily on the development and optimization of novel catalysts for the effective removal of pollutants. Covering a range of catalysts, including precious metals and nanomaterials, the research offers new insights into cost-effective and efficient pollutant removal methods. Aimed at environmental scientists, engineers, and policymakers, this publication represents a significant contribution from top researchers in the field. It serves as a key resource for those looking to understand and apply the latest advancements in wastewater treatment.
    Keywords: nanohybrid filter ; photoelectrochemical filtration ; carbon nanotubes ; MIL-101(Fe) ; tetracycline ; electrocatalytic oxidation ; anode materials ; Magnéli phase ; titanium oxide ; wastewater treatment ; iron-bearing attapulgite ; heterogeneous Fenton ; granular catalyst ; rhodamine B ; peracetic acid ; advanced oxidation ; reactive dyes ; aniline ; polyvinyl alcohol ; carbon dots ; photocatalysis ; graphitic carbon nitride ; bismuth phosphate ; tetracycline hydrochloride ; electrochemistry ; octogen ; wastewater ; hydroxyl radical ; toxicity ; catalytic membrane reactor ; noble metal catalyst ; molybdenum disulfide ; water purification ; nanoscale zero valent iron ; Cr(VI) ; adsorption kinetics ; mechanism ; modification ; nitrogen dope ; biochar ; peroxymonosulfate ; KOH activation ; bisphenol A degradation ; antibiotics ; catalytic ozonation ; emerging contaminant ; Co-Mn/CeO2 ; norfloxacin ; anode ; metal oxide ; electrolysis ; refractory pollutant ; carbon ; new biochar ; compound material ; organic pollutants ; biochar/zero valent iron ; Ti/Sb-SnO2/PbO2 electrode ; copper-containing wastewater ; active granule doping ; electrocatalytic activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The present reprint encompasses all the articles that have been accepted and published in the Special Issue entitled "Probability, Stochastic Processes and Optimization". In applied research, Probability Theory is usually regarded as a distant, often-neglected relative of Statistics. This Special Issue attempted to rectify this misconception by publishing papers presenting novel applications and original models from the natural, computer, or social sciences, based on Probability and Stochastic Processes.
    Keywords: probabilistic optimization ; spherical distribution ; multi-variate calculus ; hypergeometric functions ; transition kernel ; system of ordinary differential equations ; linear regression analysis ; theorem of existence and uniqueness ; implicit function theorem ; method of moments ; precious metals ; gold ; silver ; algorithmic trading ; futures ; asymptotics ; goodness-of-fit ; Monte Carlo simulation ; Rayleigh distribution ; Stein characterization ; Malliavin calculus ; fourth moment theorem ; multiple stochastic integrals ; multivariate normal approximation ; Gaussian fields ; random variable ; mean ; geometric mean ; entropy ; cumulative residual entropy ; Lindley distribution ; Markov chains ; Markov operators ; finitely additive Markov chains ; finitely additive measures ; invariant measures ; decompositions of Markov chains ; binomial crossover ; differential evolution ; fixed-budget analysis ; evolutionary computation ; approximation error ; exponentially modified Laplace distribution ; moments ; skewness and kurtosis coefficients ; asymmetric piecewise linear systems ; transmissibility factors ; Lyapunov equation ; ϕ-deformed (Naudts) entropy ; divergence ; relative group entropy ; generalized Fisher metric ; Fisher-like metric ; MaxEnt problem ; the alpha power inverse Weibull distribution ; step stress partially accelerated life testing ; adaptive progressive hybrid censored data ; loss functions ; continuous evolutionary algorithm ; Markov chain ; martingale ; drift analysis ; Wald’s equation ; computational complexity ; optimal control ; Lyapunov function ; system of stochastic differential equations ; Markov switches ; Poisson perturbations ; immigration ; access to employment ; regression and classification models ; collinearity and reverse causality checks ; performance comparisons and reporting ; triangulation ; cross-validations ; full support for replication of results ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Helicobacter pylori is one of the most common infections in the world, affecting roughly half of all humans. Although it is not an infection that causes death immediately after infection, it is one of the largest emerging infectious diseases in the history of humankind, causing a wide variety of diseases and, in the long term, serious complications such as stomach cancer. This Reprint contains empirical studies and reviews regarding the diagnosis, treatment, complications, and management of H. pylori infection, including new diagnostic methods, effective eradication regimens, the management of gastric cancer, and other topics.
    Keywords: gastric cancer ; biliopancreatic reflux ; gastritis ; carcinoma ; endoscopic surveillance ; Helicobacter pylori infection ; gastric stump cancer ; Helicobacter pylori ; H. pylori ; rifabutin ; treatment ; eradication failure ; culture ; bismuth ; rescue ; Hp-EuReg ; third-generation ultrathin endoscope ; transnasal endoscopy ; narrow-band imaging ; Kyoto classification of gastritis ; gastric atrophy and intestinal metaplasia ; diagnosis ; stool antigen test ; urea breath test ; peptic ulcer disease ; triple therapy ; vonoprazan ; dyspepsia ; Kyoto Classification of Gastritis ; cagA ; Okinawa ; endoscopic findings ; Helicobacter infection ; tetracycline ; eradication ; penicillin allergy ; furazolidone ; metronidazole ; amoxicillin ; child ; host genetic factor ; iron deficiency anemia ; iron demand ; iron uptake ; sports activity ; virulence factor ; gastric lymphoma ; MALT lymphoma ; radiotherapy ; chemotherapy ; rituximab ; dual therapy ; vonoprazan (VPZ) ; amoxicillin (AMOX) ; clarithromycin (CAM) ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This edition includes sixteen publications covering various applications in the field of ceramic coatings. This Issue features ceramic coatings developed through plasma spraying, magnetron sputtering, and plasma-electrolytic oxidation. It is appropriate for graduate students, scientists, and engineers interested in corrosion and wear-resistant high-temperature coatings for industrial applications.
    Keywords: glass ; glass-ceramic ; microstructure ; sealant ; SOFC ; boron coatings ; electron beam deposition ; fore-vacuum electron source ; film properties ; electron beam modification ; pressureless sintering ; composite ceramics ; electron beam ; electron-beam irradiation ; sintering ; conduction activation energy ; Al2O3-Cr ; thermal conductivity ; electrical conductivity ; forevacuum pressure region ; electron-beam evaporation ; fore-vacuum pressure range ; beam plasma ; coating deposition ; metal-ceramic coatings ; thermal barrier coatings ; atmospheric plasma spray ; suspension plasma spray ; thermal properties ; active thermography ; CrN coating ; X42Cr13 tool steel ; duplex treatment ; high-temperature nitriding ; scratch test ; wear test ; damage mechanism ; diluted magnetic semiconductor ; TM doping ; sputtering ; magnetic properties ; optical band gap ; resistivity ; multilayer DLC coating ; CrN interlayer ; nitriding ; reciprocating wear test ; tensile adhesion strength ; plasma spray coating ; MgAl2O4 ; Al2O3 ; FEA ; plasma electrolytic oxidation ; aluminum ; coating ; technological process ; experiment planning ; microhardness ; wear and tear ; cone-likeness ; friction heat resistance of materials ; carbon nanotubes ; TiC coating ; hot deformation ; aluminum matrix composite ; compression ; properties ; flow stress ; thermal fracture ; system of cracks ; functionally graded coatings ; fracture toughness ; rule of mixtures ; hard coatings ; high temperature ; HiPIMS ; wear resistance ; oxidation ; tribolayer ; flame-spraying ; fracture statistics ; QQ analysis ; Weibull distribution ; Gamma distribution ; structure-phase state ; multilayer coatings ; grain size ; curvature torsion ; phase transition ; thermal cyclic resistance ; AlCrSiN ; quaternary coating ; WC-Co ; cBN ; nano-indentation ; microscratch ; adhesion strength ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Forests are inherently linked to water resources and water-related ecosystem services. Therefore, an integrated forest–water management system is urgently required to ensure a balanced supply of hydrological and other ecosystem services from forests to meet the fast-increasing societal demands for them. This means that water aspects must be integrated into traditional forest management focusing mainly on timber production, and based on the knowledge and the latest scientific results of forest ecohydrology. Unfortunately, there are a lot of gaps in our knowledge of forest ecohydrology. This reprint presents relevant new results from scientific research on forest ecohydrology, related to the drought tolerance mechanism, hydrological properties of soil and litter layers, variation in solar radiation within stands, snowpack isotopic composition in open and forested areas, canopy transpiration and response to the main influencing factors, and the water balance components of typical forests at different regions with various climates. This knowledge can contribute to the theoretical development of forest ecohydrology and the innovative practice of integrated forest–water management to enhance the balanced supply of hydrological and other ecosystem services from forests.
    Keywords: forest ecohydrology ; stand structure ; spatial distribution ; hydrological process ; ecological process ; scale effect and scaling ; ecohydrological models ; forest&ndash ; water interaction ; integrated forest&ndash ; water management ; forest ecosystem service ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::K Economics, finance, business & management::KC Economics::KCN Environmental economics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue reprint includes one review and fifteen research articles. The review by Palyanova et al. (2023) summarized the available information on the palladian gold and proposed classifying the types of deposits based on the fineness, content, and set of impurities in palladian gold and minerals intergrown with it. Fifteen articles focused on the typomorphic features of native gold from gold deposits in Russia, India, Chile, Scotland, and Canada. This Special Issue aims to identify and generalize the reasons for variations in the compositions of native gold. I hope all the articles in this Special Issue will be helpful and valuable resources for anyone who is interested in native gold and gold deposits. I thank the Authors and Reviewers for their efforts and contributions. I am also grateful to the Editor-in-Chief, Editors and Assistant Editors of Minerals for their help.
    Keywords: geological-industrial types ; ore formations ; typomorphic features of native gold ; gold deposits in the north-east of Russia ; clinopyroxenites ; palladium gold ; platinum group minerals ; chlorite geothermometer ; sulfur isotopic composition ; placers ; gold ; Chile ; gold microchemistry ; gold morphometry ; gold provenance ; Jagpura Au-Cu deposit ; Aravalli Craton ; high fineness gold ; hydrothermal magnetite ; fluid inclusions ; IOCG-IOA type: IOCG-Co (reduced) subtype mineralization ; placer gold ; internal structures ; stages of ore formation ; endogenous and exogenous conditions ; coarse-grained structure ; high-grade shell ; recrystallization ; granulation ; deformation structures ; porpezite ; alkaline-ultrabasic rocks ; Anabar shield ; Siberian Platform ; alluvial gold ; indicator mineral ; compositional studies ; disseminated Au-sulfide mineralization ; orogenic gold deposits ; Yana–Kolyma metallogenic belt ; sulfide microtextures and mineralogy ; stable sulfur isotopes ; mineral chemistry ; source of gold ; typomorphic features ; fineness ; internal structure ; Anabar placer area ; hydrothermal-metasomatic formations ; K-feldspathization ; jasperoids ; ore mineralization ; fault zone ; ore gold ; sulfides ; gold mineralization ; metasomatites ; bismuth ; tellurides ; uytenbogaardtite ; bismoclite ; cervelleite ; native gold ; supergene gold ; the Spokoininsky cluster ; the Aldan-Stanovoy gold province ; the Aldan shield ; Pd,Hg-rich low-fineness gold ; Au-containing potarite ; substitution structure ; Itchaivayam mafic–ultramafic complex (Kamchatka, Russia) ; placer ; typomorphysm ; linear weathered crust ; Sukhoi Log deposit ; gold–sulfide–quartz (gold–arsenic) and gold–sulfide formations ; Polar Urals ; Manitanyrd ridge ; ore occurrences ; ore mineralogy ; sulfur isotopes ; palladian gold ; Pd,Cu,Ag,Hg-bearing gold ; Au-Pd ; Au-Pd-Ag ; Au-Pd-Cu ; Au-Pd-Hg ; Au-Pd-Ag-Cu ; Au-Pd-Ag-Hg ; Au-Pd-Ag-Cu-Hg systems ; minerals in association ; PGE and gold deposits ; T,P,X-conditions of ore formation ; Au-Pd mineralization types ; detrital gold ; gold alloy composition ; mineral inclusions ; indicator minerals ; gold deposit types ; British Columbia ; brannerite ; uranium mineralization ; Ozerninsky ore cluster ; Western Transbaikalia ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: There are about 30,000 plant species that are considered edible, but at present, very few of them are crops grown or cultivated on a commercially significant scale. On the other hand, there are several plants or their parts (leaves, shoots, fruits, seeds, hypogeal organs, and flowers) that are collected in the wild and consumed as raw or cooked food. Ethnobotany may offer a source of inspiration for agriculture, as wild edible species have the potential to lead food systems to be healthier, more sustainable, and resilient to climate change. Good tolerance to several abiotic and biotic stresses, as well as high nutritional value and excellent nutraceutical properties, are common traits of wild plants, making them promising candidates as new crops. Novel approaches for the outdoor/indoor cultivation of wild or underutilized species are needed to provide new opportunities for growers to produce new food categories, which would be particularly appealing to modern consumers. Cultivating wild species is also a way to preserve ethnobotanical heritage and promote genetic diversity. Furthermore, the cultivation of food plants normally gathered in the wild could reduce the health-related risks associated with pollution and biological contamination.
    Keywords: Edible species ; Cultivation systems ; Yield and quality ; New functional foods ; Nutrients ; Secondary metabolites ; Antioxidants ; Food security ; Food safety ; Biodiversity. ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    Publication Date: 2024-02-27
    Description: Collective monograph contains the results of scientific research devoted to new views and proposals for the diagnosis of certain diseases. The proposed solutions are important for clinical practice and inspire optimism in obtaining encouraging results in overcoming some pathologies. Chapter 1 is dedicated to endoscopic retrograde cholangiopancreatography - a contrast study of the bile ducts and ductal system of the pancreas, which is achieved by their cannulation with the help of a flexible endoscope and their visualization by X-ray (fluoroscopy). Thanks to this, it becomes possible to diagnose and perform medical interventions for choledocholithiasis, benign and malignant obstruction of the bile ducts, chronic pancreatitis accompanied by obstruction of the pancreatic ducts. Chapter 2 presents the results of the development of a thermoelectric device for diagnosing inflammatory processes and pain syndrome in degenerative-dystrophic diseases of the lumbosacral spine. Such a device makes it possible to save, process and visualize measurement results on the display of the device and on a personal computer in real time. The results of clinical studies of thermometric indicators in the lumbosacral region of the spine in persons with chronic pain syndrome against the background of degenerative-dystrophic pathology of the spine in the presence of hernias and protrusions of intervertebral discs are given. The effectiveness of the proposed thermoelectric device in medical practice has been confirmed. Chapter 3 presents the results of the examination of various contingents of the population: students, athletes, mobile operators, people with hearing loss, post-covid syndrome and psychophysiological lability developed under martial law. The features of information processing by examinees with different degrees of functional mobility of nervous processes are highlighted. It was found that the deprivation of auditory function, post-conviction syndrome, psychophysiological lability developed in the conditions of martial law significantly reduce the level of neural processes and the ability to process information. The evaluation scales of neurodynamic and sensorimotor functions proposed for use in the medical field can be used to optimize diagnosis and increase the effectiveness of monitoring neurological morbidity, including in people with special needs. Chapter 4 is devoted to the problems of children's neuropsychiatric diseases, in particular brain damage in children with ASD. Restrained optimism is expressed for the prospect of overcoming this severe psychiatric pathology in the foreseeable future due to the introduction of genetic, biochemical and immunodiagnostic approaches, as well as metabolic and immunotherapeutic interventions with neuroprotective effects. Arguments are presented in favor of the fact that the successful testing in clinical practice of evidence-based personalized multidisciplinary strategies of diagnosis and treatment will allow a breakthrough in the clinical management of children with severe mental disorders in the near future. This will provide not only the possibility of recovery from a prognostically unfavorable and currently incurable neuropsychiatric disorder, but will also contribute to stopping the large-scale threatening epidemic of neuropsychiatric syndromes in the modern child population. Chapter 5 presents the evolution of views on the problem of Internet addiction, provides information on its prevalence, comorbidity with mental disorders, and provides an overview of modern clinical classifications and psychometric tools for its diagnosis. A single definition of "cyber addiction" is singled out, based on the fact that the object of addiction is interaction with various information resources and technical means. The proposed clinical diagnostic criteria, which are based on the criteria for the diagnosis of mental and behavioral disorders due to the use of psychoactive substances ICD-11, and the characteristics of the boundary with normative behavior when using various information resources and technical means are provided. The development and validation of a new psychodiagnostic screening tool based on the proposed cyber addiction paradigm, the YSCAS scale, is presented. The monograph is intended for doctors and practitioners who are engaged in the search and implementation of effective diagnostic methods to overcome the problems associated with the detection and treatment of certain pathologies. The monograph can also be useful to postgraduate and master's students of universities in the relevant educational and scientific profile.
    Description: Published
    Keywords: Endoscopic retrograde cholangiopancreatography ; Endoscopic lithoextraction ; Osteochondrosis of the spine ; Thermoelectric device ; Individual-typological properties ; Functional mobility ; Sensorimotor reactivity ; Autism spectrum disorders ; Attention deficit hyperactivity disorder ; Obsessive-compulsive syndrome ; Immunodiagnostics ; Internet addiction ; Cyberaddiction ; YSCAS scale ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint focuses on the importance of the micronutrient iron in human physiological iron homeostasis and iron-related diseases. Daily adequate dietary iron supply ensures vital body functions and hemoglobin synthesis during erythropoiesis. During the last few decades, scientific evidence has shown that the maintenance of human iron homeostasis is an important factor for physical and mental health. The present reprint gives an overview of how iron, as an essential dietary element, is responsible for physiological and pathological biochemical processes in the human body. For the readership, this relevant information will provide an evidence-based update on the complex regulatory mechanisms and related diseases of iron metabolism.
    Keywords: iron metabolism ; iron homeostasis ; micronutrient iron ; physiology ; pathology ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MF Pre-clinical medicine: basic sciences::MFG Physiology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Biomaterials are natural or artificial materials used to manufacture implants to replace lost or diseased biological structures in order to restore form and function. Biomaterials that require long-term service, such as orthopedic implants, need good physical and chemical stability, such as stainless steel and titanium alloys. The application of metal in biomedicine is becoming more and more common, but due to its various limitations, it is often necessary to modify its surface to obtain better performance and better clinical application. There are many technologies for the surface modification of medical metals, such as laser surface modification, chemical treatment, plasma surface modification, etc., and these technologies are still being developed to meet market demand. This reprint will provide important contributions related to the announced topics, focusing on biomedical metals and the surface modification technologies of biomedical metals.
    Keywords: titanium ; surface modification ; surface topographies ; multifunctional surfaces ; metamaterials ; 4D printing ; ZK60 magnesium ; micro-arc oxidation ; atmospheric plasma spraying ; corrosion ; additive manufacturing ; porous titanium ; implant coatings ; antibacterial agent ; laser cladding ; Ca/P bio-ceramic coating ; biocompatibility ; bioactivity ; wear resistance ; magnetite ; conversion coating ; optimization ; invitro cytotoxicity ; beta titanium alloy ; elastic modulus ; corrosion property ; osseointegration ; Ti-matrix composites (TMCs) ; graphene oxide (GO) ; mechanical properties ; reinforcement ; laser-induced periodic surface structures ; femtosecond laser processing ; functional surfaces ; application ; composite ; 3D printing ; bioresorbable Fe-Cu-hydroxyapatite composite ; titanium alloy ; phosphate layer ; biomaterial ; zinc phosphate ; scholzite ; PVA films ; boric acid ; polyhexamethylene guanidine hydrochloride ; antimicrobial properties ; surface treatment ; titanium alloys ; microstructure ; physicochemical properties ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue addresses recent advances in the research of plant-derived natural products, their mechanisms of action and how they can influence health and disease. Plant-derived natural products have been well known since antiquity due to their beneficial effects on human health, and since then, they have attracted the interest of the scientific community, leading to the identification, isolation and quantification of their compounds and research on their biomedical properties. They have been found to be rich in phytochemicals, such as terpenes and phenolic compounds, with proven antioxidant, anti-inflammatory, antimicrobial, antitumor and prebiotic properties, and therefore, they have been suggested as potential candidates for the therapeutic management of several chronic diseases. Some of them include inflammatory bowel disease, diabetes, non-alcoholic fatty liver disease, arthritis and cancer, in which inflammation, oxidative stress and dysbiosis mechanisms are implicated. Furthermore, given the increased economic burden, the side effects and the low compliance rates of patients who receive standard medical treatments, plant-derived natural products could possibly serve as adjunct therapeutic agents for chronic diseases.
    Keywords: plants ; natural products ; free radicals ; inflammation ; medicinal ; caffeic acid ; antibacterial ; antifungal ; antioxidant ; anticancer ; juglone ; Juglans regia ; mogrol ; mogroside ; phytochemical ; pharmacology ; osteoporosis ; antiobesity ; anti-inflammation ; neurodegenerative disorders ; anticancer agents ; aromadendrane ; bryophytes ; cytokinesis inhibitor ; Plagiochila species ; plagiochilins ; analgesic activity ; traditional medicine ; wound healing ; colon carcinogenesis ; 1,2 dimethylhydrazine ; hesperetin ; capecitabine ; Jatropha tanjorensis ; Fraxinus micrantha ; HPTLC ; anti-obesity activity ; high-fat diet model ; histological ; Alzheimer ; acetylcholinesterase inhibitors ; Euonymus laxiflorus Champ. ; bioactive compounds ; medicinal plants ; P. lentiscus ; GC/MS ; HPLC-DAD ; antioxidant activity ; antibacterial activity ; antifungal activity ; extract ; molecular docking ; Artemisia arborescens ; Artemisia inculta ; phenolic compounds ; terpenes ; trace metals ; antioxidant capacity ; Eurycoma longifolia Jack ; anti-inflammatory ; antinociceptive effect ; antipyretic effects ; gastroprotective activity ; gastric ulcer ; Thai traditional medicine ; phytochemicals ; inflammatory bowel disease ; gut microbiota ; Mastiha ; Curcumin ; Boswellia serrata ; Artemisia absinthium ; lipidomic profile ; Tulsi ; Ocimum sanctum ; ischemic stroke ; photothrombotic ischemia ; medicinal plant ; n/a ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Translational research is required to uncover the underlying pathomechanisms of neurological and psychiatric disorders, search for new biomarkers, and develop novel therapeutics. Complex polygenic, multifactorial, and heterogeneous mechanisms have been elucidated using in vivo and in vitro models. Advanced preclinical models have recently revealed an intriguing interaction between sex/gender and aging in the pathogenesis and clinical manifestations of neuropsychiatric disorders. Despite these advances, much work remains to be carried out to fully understand the underlying pathology of these conditions and to develop treatments that can significantly improve the lives of those who suffer from them. The current challenge in the field of neurological and psychiatric disorders is the development of disease-modifying, effective treatments for these complex and long-term debilitating conditions with a high malady burden. The first edition of this research topic, entitled 'Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models,' emphasizes the importance of translational research in bridging the gap between basic research and clinical applications. Furthermore, it provided a venue for researchers to share their findings and progress in translational research in this field.
    Keywords: Alzheimer&rsquo ; s disease ; Parkinson&rsquo ; multiple sclerosis ; stroke ; migraine ; pain ; depressive disorder ; anxiety disorder ; autism spectrum disorder ; sleep wake disorders ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 86
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: undefined
    Keywords: Medicine ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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  • 87
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Various classes of natural and synthetic molecules that can be classified as biomaterials find application in all fields of dentistry. Biomaterials should be biocompatible to minimise toxicity and bioactivity to ensure or simulate biological effects. They are used, for instance, to enhance antibacterial activity and improve the healing process. Calcium silicates, for illustration, are biomaterials used in endodontics that have proven their excellent biological, physico-chemical, and mechanical properties. However, some of these are considered too soluble, and this is almost completely due to their hardness when used as endodontic sealers, making endodontic retreatment very difficult. Despite manufacturers' best efforts, it is sometimes difficult to marry bioactivity, biocompatibility, and clinical benefits in a biomaterial; therefore, in this content, the work of researchers is invaluable.
    Keywords: calcium silicate cement ; retrograde materials ; premixed cement ; powder–liquid cement ; chemical composition ; EDX ; caries prevention ; anterior restorations ; ceramic ; dental veneers ; follow-up ; non-vital teeth ; porcelain laminate veneers ; vital teeth ; antimicrobial ; osseointegration ; surface modification ; tissue engineering ; root canal retreatment ; calcium silicate-based cement ; ProTaper Universal Retreatment ; D-Race ; dentin hypersensitivity ; desensitizing agents ; calcium phosphate ; hydroxyapatite ; nano-hydroxyapatite ; peri-implantitis ; periodontitis ; periapical radiograph ; deep learning ; neural networks ; image enhancement ; carious lesion activity ; irreversible pulpitis ; partial pulpotomy ; vital pulp therapy ; mineral trioxide aggregate ; furcation involvement ; image segmentation ; Gaussian high-pass filtering ; image preprocessing ; CNN ; calcium silicate material ; confocal laser scanning microscope ; deciduous tooth ; digital microscopy ; flowability ; micro-CT ; pulpectomy primary teeth ; root canal filling ; SEM ; zinc oxide eugenol ; bic Book Industry Communication::M Medicine
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The healthcare system’s ability to diagnose and care for people with schizophrenia has improved in recent decades, as effective pharmacological and psychosocial interventions are now available. However, schizophrenia remains a leading cause of disability and premature mortality. The utilization of pharmacological and psychosocial interventions in the healthcare system, which have the potential to significantly improve the quality of life for people with schizophrenia, heavily depends on medical professionals completing accurate and comprehensive assessments of patients’ psychopathologies, cognitive profiles, physical health statuses and any environmental factors that may influence them. This Special Issue reprint on schizophrenia, from the Journal of Clinical Medicine, presents a collection of articles on current approaches to assessment and treatment, as well as new findings and future perspectives of schizophrenia research and care.
    Keywords: schizophrenia ; ERP ; mismatch negativity ; MMN ; P3a ; illness duration ; real-life functioning ; motivation circuits ; negative symptoms ; RDoC ; positive valence system ; salience system ; deficit syndrome ; diagnosis ; cognitive function ; social skills training ; physical comorbidities ; childhood abuse ; internalized stigma ; neutrophil-to-lymphocyte ratio ; antipsychotics ; hypothyroidism ; inflammatory markers ; expressive deficits ; experiential deficits ; functioning ; quality of life ; first psychotic episode ; first episode ; emotional processing ; social cognition ; MCCB ; MSCEIT ; real-world studies ; real-world effectiveness ; tolerability ; treatment adherence ; second-generation antipsychotics ; long-acting injectable antipsychotics ; delusional disorders ; psychosis ; sex ; women ; psychopathology ; construct ; schizophrenia spectrum ; renaming ; rethinking ; revising ; effort expenditure ; recent-onset schizophrenia ; persistent negative symptoms ; motivation ; neuropeptide S ; cognitive functioning ; rehabilitation ; AEP ; QEEG ; switch ; extrapyramidal symptoms ; treatment ; cognitive deficits ; self-evaluation of negative symptoms ; health-related quality of life ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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  • 89
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Steroids are a large group of compounds whose structure is based on a 17-carbon skeleton, with a specific cyclopentanoperhydrophenanthrene ring system. Natural steroids have been fine-tuned through evolution to build membranes; act as chemical messengers that regulate metabolic, immune and reproductive functions in animals and stimulate the growth of, or otherwise protect, animal organisms. The steroid core represents a suitable motive for structural modifications. Therefore, a large group of semi-synthetic steroid derivatives have occupied the attention of synthetic chemists as well as medicinal chemists due to their potential biological activity, including anticancer, antibacterial, anti-inflammatory and (anti)hormonal activities.This Reprint of the Special Issue of Molecules titled “Steroid Compounds with Potential Biological Activity” is dedicated to both experimental and theoretical studies on steroid chemistry, structural biology, biosynthesis, metabolism, and pharmacology. The Issue focuses on the isolation and synthesis of steroid compounds, diverse in origin, as well as their structural characterization and identification. Published articles and reviews relate to in vitro and in silico studies of the pharmacological properties, molecular biology, biochemistry and structural biology of steroids.
    Keywords: 4-azasteroids ; 4-azapregnenes ; aldol condensation ; molecular docking ; antiproliferative activity ; Paracaudina chilensis ; Molpadida ; triterpene glycosides ; chilensosides ; sea cucumber ; cytotoxic activity ; 26-thiodiosgenin ; thiol oxidation ; sulfoxides ; sulfones ; sapogenins ; steroids ; antimicrobial activity ; cytotoxicity ; breast cancer ; endocrine therapy ; endocrine resistance ; aromatase inhibitors ; exemestane ; oxymestane ; anti-cancer properties ; multi-target compounds ; aromatase ; estrogen receptor ; androgen receptor ; Chan–Lam reaction ; diaryl ether ; 13α-estrone ; antiproliferative effect ; tubulin polymerization ; molecular dynamics ; oximes ; chemistry ; antitumor ; anti-inflammatory ; antibacterial ; antifungal ; antiviral ; triterpenoids ; isoprenoid lipids ; anti-neoplastic ; anti-fungal ; anti-bacterial ; anti-viral ; fungal endophytes ; plants ; marine invertebrates ; furanosteroids ; fungi ; marine organisms ; diacetoxy-5α-cholestane ; crystal structure HSA binding ; multi-spectroscopy ; DFT ; steroid dimers ; 1,4-phenylene-linked dimers ; montmorillonite ; DHEA ; cholesterol ; cation channels ; TRPML1 ; bioisostere ; estrogens ; ring cleavage ; protective groups ; pyridines ; pyrimidines ; cyclization ; antimetabolites ; cell growth inhibition ; gene expression ; HeLa cells ; in vitro culture ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Acousto-optic technologies have increasingly attracted the attention of scientists and engineers. Acousto-optic interactions have become the flexible basis of compact and robust devices for the analysis of the intensity, spectrum, polarization, and other properties of light. In this book, modern trends of acousto-optical spectral technologies, including the fundamentals and optimization of existing techniques, are highlighted and discussed. This reprint provides a forum for reports on technical developments that allow the spectral analysis of various objects to take place. The goal of this reprint is to provide readers with an overview of the hot topics and the state of the art regarding the applications of acousto-optic techniques, including new materials and structures, theoretical and experimental studies of light diffraction by ultrasonic waves, spectroscopy, and spectral imaging.
    Keywords: acousto-optics ; phased-array piezoelectric transducers ; acousto-optic materials ; anisotropic Bragg diffraction ; acousto-optic devices ; spectral imaging ; acousto-optic interaction ; image quality ; confocal scheme ; collimating scheme ; AOTF spectrometer ; in situ measurement ; lunar surface ; terahertz radiation ; diffraction ; liquefied inert gas ; transparent electrode ; mesh structure ; sheet resistance ; transparency ; groove ; lithography ; chemical deposition ; shielding efficiency ; acousto-optic crystals ; propagation of acoustic waves ; non-destructive testing ; impulse acoustic microscopy ; AOTF ; AutoML ; feature wavelength selection ; near infrared detection system ; aberrations ; coordinate mapping ; figure of merit ; monoclinic crystal ; potassium rare-earth tungstate ; two-dimensional phononic crystals ; fused silica ; finite element method ; polarization of acoustic waves ; acousto–optic interaction ; acousto-optic ; tunable filter ; surface plasmon resonance ; surface electromagnetic wave spectroscopy ; thin film thickness ; wavelength and angular interrogation ; refractive index sensing ; AOTF spectral imager ; geometric calibration of AO crystal ; spectral response ; imaging aberrations ; tuning curve ; acousto-optic interaction geometry ; polar angular analysis ; tolerance analysis ; spectral imaging system ; polarization multiplexed ; high throughput ; color reproduction ; spectral power distribution ; Bragg diffraction ; multi-wavelength light filtration ; image processing ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics ; bic Book Industry Communication::P Mathematics & science::PH Physics::PHJ Optical physics
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: This reprint is the printed edition of the Special Issue published in Materials. The reprint provides an overview on current international research activities in the field of advanced pulse laser machining technology. It covers fundamental and applied aspects and collects contributions of renowned scientists from academics and industries working in the fields of laser processing, materials science, physics, chemistry, and engineering in order to foster the current knowledge and present new ideas for future applications and new technologies.
    Keywords: multi-beam micromachining ; beam splitting ; invar ; shadow masks ; OLED ; nanosecond laser ; direct laser interference patterning ; design of experiments ; central composite design ; morphological filtering ; surface texture homogeneity ; micro structuring ; bearing steel ; dual laser beam processing ; excited state absorption ; semiconducting thin films ; stimulated emission depletion ; femtosecond laser ; silicon ; amorphization ; crystallization ; spectroscopic imaging ellipsometry ; transmission electron microscopy ; atomic force microscopy ; laser ablation ; ultrafast ; re-deposition ; fs-laser writing ; waveguides ; element redistribution ; Soret effect ; diffusion competition effects ; ultra-short pulses ; double pulses ; burst processing ; MHz bursts ; GHz bursts ; X-ray emission ; micromachining ; dose rate ; X-ray spectrum ; ultrafast laser ; laser ; ultrashort pulse ; plasma ; X-ray ; Bremsstrahlung ; resonance absorption ; burst ; bi-burst ; beam shaping ; squared top-hat ; fs-laser ; laser surface structuring ; laser-induced periodic surface structures ; micro-channels ; glass ; ultrafast laser processing ; Bessel beam ; X-ray emission hazards ; ultrashort pulsed laser ; radiation protection ; industrial applications ; protection housing ; ambient dose rate ; pulsed laser ; laser micromachining ; mechanical shutter ; solenoid shutter ; electro-optic modulator shutter ; opening time ; lifetime ; X-ray energies ; X-ray dose rate ; laser printing ; laser-induced forward transfer (LIFT) ; digital manufacturing ; additive manufacturing ; printing of materials ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistry
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  • 92
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Landscapes and cultural heritage have faced many challenges over time, including modifications and degradation that appear with time, overlaps with other challenges not previously observed, and the influence of cities and management. One of the most visible and globally discussed challenges is climate change. Therefore, there is an urgent need to launch initiatives to tackle climate change and other current challenges from the perspective of landscape and cultural heritage protection. This Special Issue presents selected papers of studies conducted in relation to the 28th Conference on the Series of Garden Art and Historical Dendrology entitled “Climate Change and Current Challenges for Landscapes and Cultural Heritage” that was held on 28 and 29 October 2021. This collection serves as a platform for the exchange of experiences among researchers from different scientific domains.
    Keywords: nature reserves ; landscape fragmentation ; north–south transitional zone ; spatial differentiation ; Qinling–Daba Mountains ; habitat quality ; water dams ; Krakow fortress ; climate change ; environmental management ; cultural heritage conservation ; urban densification ; prefabricated housing estates ; spatial devastation ; protection of urban layout ; Cracow ; climate change mitigation ; cultural heritage ; urban renewal ; urban parks ; therapeutic landscapes ; climate resilience ; vernacular heritage ; climate narratives ; climate adaptation ; climate stories ; courtyard ; urban green infrastructure ; urban pattern ; supervised classification ; ecosystem services (ES) ; urban cemeteries ; biocultural diversity (BCD) ; urban green infrastructure (UGI) ; questionnaire survey ; Leipzig ; Łódź ; sensory gardens ; urban green spaces ; aromatic herbs ; plant smell memory ; stress ; human wellbeing in urban areas ; restorative environments ; history of gardens ; castle garden ; goosefoot avenue ; star-shaped garden layout ; Austro-Hungarian Empire ; Transylvania as part of Romania ; green infrastructure ; resilience management ; biodiversity ; scenario analysis ; cellular automata model ; historic psychiatric hospitals ; therapeutic landscape ; green therapy ; horticulture therapy ; historical commons ; human cultural heritage ; local development ; landscape values ; rainwater management ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: The purpose of this Special Issue was to collect and present research results and experiences on energy supply in the Visegrad Group countries. This research considers both macroeconomic and microeconomic aspects. It was important to determine how the V4 countries deal with energy management, how they have undergone or are undergoing energy transformation and in what direction they are heading. The articles concerned aspects of the energy balance in the V4 countries compared to the EU, including the production of renewable energy, as well as changes in its individual sectors (transport and food production). The energy efficiency of low-emission vehicles in public transport and goods deliveries are also discussed, as well as the energy efficiency of farms and energy storage facilities and the impact of the energy sector on the quality of the environment.
    Keywords: energy supplies ; energy security ; energy market ; EU countries ; Hellwig’s method ; sustainability strategies ; sustainable development ; Visegrád Group ; sustainable strategic management ; the renewable energy sector ; energy use ; structures ; food production systems ; Visegrad Group ; energy mix ; renewables ; energy in transport ; energetic efficiency ; energy sources ; economic growth ; developing and developed countries ; energy sector ; environmental quality ; renewable energy sources (RES) ; nuclear energy ; southeastern Poland ; sustainability ; renewable energy sources ; European Union ; cluster analysis ; Visegrad Group countries ; fuels ; cointegration ; Granger causality ; electricity prices ; households ; directions of price changes ; biogas energy ; solar energy ; hybrid biogas plant ; renewable energy ; circular economy ; off-grid systems ; energy efficiency ; social and economic aspects of energy ; economic efficiency ; low emissions ; zero emissions ; e-commerce ; last mile ; parcel lockers ; efficiency of logistics processes ; economies of scale ; simulation of logistics processes ; COVID-19 ; BESS management ; price arbitration ; shift load ; microgrid ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PH Physics
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  • 94
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This Special Issue, “Mapping Indigenous Knowledge in the Digital Age”, explores Indigenous engagement with geo-information in contemporary cartography. Indigenous mapping, incorporating performance, process, product, and positionality as well as tangible and intangible heritage, is speedily entering the domain of cartography, and digital technology is facilitating the engagement of communities in mapping their own locational stories, histories, cultural heritage, environmental, and political priorities. In this publication, multimodal and multisensory online maps combine the latest multimedia and telecommunications technology to examine data and support qualitative and quantitative research, as well as to present and store a wide range of temporal/spatial information and archival materials in innovative interactive storytelling formats. It will be of particular interest to researchers engaged in studies of global human and environmental connection in the age of evolving information technology.
    Keywords: transdisciplinary research ; knowledge dialog ; participatory mapping ; qualitative analysis ; community-based management ; Dawes ; allotment ; GIS ; map ; automation ; PLSS ; geographic information systems ; reservation ; indigenous ; Standing Rock ; community mapping ; learning community ; natural resources management ; Cyberatlas ; Native Americans ; first nations ; historic cartography ; toponymy ; Indigenous maps ; indigital ; undergraduate education ; native science ; Inuinnait ; Inuinnaqtun ; cybercartography ; digital return ; multi-media cartography ; digital heritage ; native guidance system ; Lençóis Maranhenses region ; Maranhão coast ; traditional communities ; Cybercartographic Atlas ; indigenous mappings ; decolonial cartography ; mythical spaces and indigenous orientations ; sky map ; collaborative work ; Pa Ipai ; Baja California ; Mexico ; mapping ; reconciliation ; art ; digital pedagogy ; reflexivity ; Cybercartography ; GIAMedia ; FOSS ; intercultural literacy ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::R Earth sciences, geography, environment, planning::RG Geography
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  • 95
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: This Special Issue highlights fundamental changes to the questions that we can ask about both the recent past and deep time. Delve into the forefront of paleontological research with this Special Issue reprint. Renowned paleontologists from around the world share groundbreaking insights into ancient life on Earth. Discover the latest advances in fossil discovery, analytical techniques, interdisciplinary collaborations, and technological innovations that are shaping our understanding of evolution and the Earth's history. This collection of cutting-edge research is a must-read for scientists, researchers, and enthusiasts interested in the dynamic field of paleontology in the modern era.
    Keywords: REE ; Tyrannosaurus rex ; molecular paleontology ; geochemical taphonomy ; diagenesis ; bone ; protein ; collagen ; Hell Creek Formation ; cuticle ; Eocene ; Fur Formation ; insects ; melanin ; mo-clay ; pigment ; Stolleklint Clay ; structural coloration ; Ølst Formation ; fossil ; dinosaur ; paleoproteomics ; porphyrin ; keratin ; feather ; taphonomy ; degradation ; microbes ; CO2 ; apatite ; paleontology ; China ; history ; 20th century ; 21th century ; paleobiology ; history and philosophy of paleontology ; twenty-first-century paleontology ; paleobiological revolution ; technoscience and global issues ; fossil proteins ; rare earth elements ; soft-tissue preservation ; geochemistry ; soft tissues ; molecular preservation ; Hornerstown Formation ; shallow marine ; glauconite ; hybridization ; introgression ; ancient DNA (aDNA) ; hominin paleontology ; paleoanthropology ; Brachylophosaurus ; Judith River Formation ; ELISA ; RIA ; Venta Micena site ; VM-0 ; VM-1960 ; taxonomy ; morphometrics ; phylogeny ; evolution ; morphological clock ; molecular clock ; biodiversity ; palaeobiogeography ; macroevolution ; primates ; Cercopithecidae ; monkeys ; genotype:phenotype mapping ; dentition ; Equidae ; Equinae ; hipparionini ; protohippini ; equini ; paleoecology ; paleoclimatology ; biochronology ; steroids ; diet ; coprolites ; Gryphaea dilatata ; crystallographic texture ; pole figures ; neutron diffraction ; recrystallization ; thick-walled shells ; molecular taphonomy ; fossils ; preservation ; mass spectrometry ; dinosaurs ; Neanderthal ; Combe-Grenal ; juvenile ; mandible ; periodontitis ; tooth ; tartar ; SEM analysis ; n/a ; terrestrialization ; artrhopods ; Cambrian explosion ; molecular clocks ; palaeontology ; phylogenomics ; teeth ; enamel ; microanalysis ; Purussaurus ; Neoepiblema ; miocene ; ICP-MS ; MEV ; microscopy ; magnetic resonance imaging ; micro-computed tomography ; radiocarbon dating ; DNA barcoding ; synchrotron ; bone remodeling ; elemental analysis ; diagenetic alteration ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Advancements in digital technologies are reshaping the world of dentistry, from prosthodontics to implant dentistry. Intraoral scanners, facial scanners, 3D printers, and milling machines have revolutionized the clinical approach and operative workflow in daily practice. However, digital dentistry brings several challenges to clinicians due to the rapid evolution of new technologies and the lack of evidence-based guidelines for their correct use. The aim of this Special Issue is to cover the latest advances in the development and application of digital technologies in prosthetic and implant dentistry. We wish to provide both clinicians and researchers with a comprehensive and up-to-date source of information on current trends, limitations, and potential future applications of digital technologies in daily clinical practice.
    Keywords: dental implants ; digital impression ; intraoral scanner ; CAD/CAM materials ; toothbrushing wear ; surface ; roughness ; surface integrity ; alveolar remodeling ; tooth extraction ; intraoral digital scanning ; imaging superimposition ; less traumatic surgery ; socket healing ; implantology ; computer-aided surgery ; image-guided surgery ; zygomatic implants ; navigation system ; dental implant ; bone level ; prospective study ; sub-crestal placement ; emergence profile ; guided surgery ; digital workflow ; stereolithographic surgical guide ; accuracy ; CAD–CAM ; DICOM–STL ; static guided surgery ; clinical study ; intraoral scanners ; digital dentistry ; impression techniques ; full-arch impression ; elderly population ; dimensional measurement accuracy ; implant scan ; operator ; precision ; scan area ; trueness ; occlusion ; overloading ; complications ; implant-supported restorations ; marginal bone loss ; oral implantology ; intraoral scan ; cone-beam computed tomography ; oral surgery ; emergence angle ; retrospective study ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Nearly 18 months later, COVID-19, caused by SARS-CoV-2, continues to present significant challenges to health systems, public health, and the economy of countries across both hemispheres. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed hospitals and clinics in many countries and continue to do so. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This Special Issue collection follows on from the Special Issue “COVID-19: Current Challenges and Future Perspectives” and provides an avenue for authors from various disciplines to provide feedback on the response to and our future global preparedness for COVID-19, as well as to disseminate critical information about SARS-CoV-2 and the associated COVID-19 pandemic.
    Keywords: COVID-19 ; new-onset DM ; severe infection ; mortality ; outbreak ; P.1 variant ; Gamma variant ; SARS-CoV-2 infection ; whole-genome sequencing ; pandemic ; overweight ; obesity ; Peru ; psychological impacts ; public health ; preparedness ; mRNA-1273 ; BNT162b2 ; TAK-919 ; SARS-CoV-2 ; post-vaccination ; healthcare personnel ; vaccination ; asymptomatic infection ; HIV ; infectious disease ; excess mortality ; regdanvimab ; remdesivir ; severe ; community transmission ; population density gradient ; Dhaka ; Bangladesh ; dengue ; undifferentiated febrile illness ; antigen testing ; variants ; reinfections ; breakthrough infections ; vaccine hesitancy ; sub-Saharan Africa ; pulmonary fibrosis ; postacute COVID-19 syndrome ; tuberculosis ; helminth coinfection ; coronavirus ; coordination ; health operations and technical expertise ; AFRO ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; liver transplantation ; reproduction rate ; phylogenetic analysis ; clade GK ; D614G ; P681R ; cross-reactivity ; haemorrhage ; thrombocytopenia ; thrombosis ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) ; molecular diagnostics ; real-time polymerase chain reaction (RT-qPCR) ; economy ; income levels ; waves ; policy ; turning points ; occupational exposure ; risk factors ; personal protective equipment ; SIR model ; socio-behavioral aspects ; interaction distance ; school reopening strategy ; self-medication ; over-the-counter ; medicine use ; Pakistan ; clinical features ; Luanda ; Angola ; socioeconomic status ; risk perception ; risk prevention practices ; qualitative ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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  • 98
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-08-08
    Description: The World Health Organization recommends the consumption of plant foods instead of animal-origin foods due to their high levels of saturated fat and cholesterol. Consumption of plant products has led to research on the beneficial properties of their components beyond basic nutrients. Vegetable-derived peptides have shown multifunctional effects related to chronic diseases, attracting interest from the food, nutraceutical, and pharmaceutical industries. This reprint highlights studies on various vegetable extracts, such as chestnut, quinoa, amaranth, buckwheat, and Protium heptaphyllum gum resin, which have demonstrated antimicrobial, anti-inflammatory, and cholesterol-regulating properties. Specific compounds derived from plants, such as methyl p-coumarate and lupin protein hydrolysate, have shown effectiveness in reducing inflammation and anxiety, respectively. A vegetable extract of rosemary has been studied for its potential to treat osteogenesis imperfecta. Moreover, this repprint reviews Lycium barbarum berries, essential oils from Annonaceae species, antioxidant compounds, phytosterols, and natural compounds for the prevention and treatment of oral mucositis was discussed. Overall, these studies suggest that vegetable-derived bioactive compounds could serve as new nutraceuticals to prevent and treat a wide range of chronic diseases.
    Keywords: hypercholesterolemia ; gene expression ; HMGCR ; PCSK9 ; PPARα ; enzymatic activity ; molecular docking ; statin ; monacolin ; breu branco ; seed storage proteins ; peptides ; anti-inflammatory ; antioxidant ; trypsin inhibitors ; quinoa ; amaranth ; buckwheat ; in vitro gastro-intestinal digestion ; natural products ; Brazilian species ; essential oil ; applications ; phytosterols ; neurodegeneration ; Alzheimer’s disease ; blood brain barrier ; obesity ; oxidative stress ; dyslipidemia ; diabetes ; enzyme-assisted extraction ; plant material ; phenolic compounds ; oligosaccharides ; prebiotic ; nanocellulose ; nanofibers ; fermentation ; sustainability ; cancer ; drug delivery ; oral mucositis ; treatment ; lupin ; protein hydrolysates ; anxiety ; ApoE−/− ; functional foods ; peptidomics ; rosemary extract ; collagen type I ; unfolded protein response ; autophagy ; proteasome ; skin fibroblasts ; apoptosis ; osteogenesis imperfecta ; asthma ; methyl p-coumarate ; Th2 cytokines ; eosinophil ; NF-κB ; Castanea sativa shells ; Subcritical Water Extraction (SWE) ; antimicrobial activity ; goji berries ; pro-healthy effects ; phenolics ; biological properties ; functional ingredients ; in vitro cultures ; Ruta montana ; coumarins ; alkaloids ; antibiofilm formation ; antibacterial activity ; antioxidant activity ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences ; bic Book Industry Communication::J Society & social sciences::JF Society & culture: general::JFC Cultural studies::JFCV Food & society
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Considering the worldwide problem of aquatic pollution, we proposed this reprint, which presents a collection of articles on different aspects of environmental pollution, from monitoring to the evaluation of toxicity. In particular, the volume concerns the issues specifically related to emerging contaminants in aquatic environments, such as plastics and pharmaceuticals. However, to confer to this volume a more holistic view, some articles on priority pollutants, such as heavy metals and pesticides, are also reported.
    Keywords: aquatic ecosystems ; pollution ; monitoring ; toxic effects ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science::PN Chemistry
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: This Special Issue of the journal Axioms collects submissions in which the authors report their perceptions and results in the field of mathematical physics and/or physical mathematics without any preconditions of the specific research topic. The papers are intended to provide the reader with a broad window into the status of the research field showing our understanding of how a known concept changes our thinking in that area of science. The papers in the Special Issue highlight the current two issues in physics and mathematics under hot debate: fractional calculus and entropy.
    Keywords: weak detonation ; high activation regime ; nonlinear PDEs ; Fuchsian reduction analysis ; Lorentz transformation ; blow-up ; hot spot ; chemically reactive flows ; nonlinear equations in partial derivatives ; hyperbolic equations ; Bäcklund transformations ; Clairin’s method ; differential relationships ; the Liouville equation ; symbolic calculus ; canonical system of q-difference equations ; q-Euler integral ; multi-term fractional differential equation ; quasilinear equation ; Riemann–Liouville fractional derivative ; defect of Cauchy type problem ; fixed point theorem ; initial-boundary value problem ; deformed numbers ; deformed algebras ; deformed calculus ; nonadditive entropy ; vibration control ; boundary control ; intermediate state control ; separation of variables ; Riemann–Liouville fractional differential equations ; nonlocal boundary conditions ; positive parameters ; positive solutions ; existence ; nonexistence ; Patlak–Keller–Segel systems ; the Cattaneo model of chemosensitive movement ; hyperbolic models ; shock waves ; conservation laws ; constrained Hamiltonian system ; canonicalization ; symplectic method ; numerical simulation ; extended Chebyshev functional ; generalized proportional Hadamard fractional integral operator ; manipulation system ; geometric approach ; noninteraction ; two-phase flow ; Sobolev spaces ; analytic semigroups ; fractional interpolation ; local and global solutions ; seismic tensorial force ; far-field seismic waves ; near-field seismic waves ; seismic mainshock ; quasi-static deformations ; mathematical physics ; Elliott Lieb ; the International Association of Mathematical Physics (IAMP, history and development) ; Letters in Mathematical Physics (LMP) ; history ; God as an (optional) axiom ; metamathematics ; symmetries ; particle physics ; n/a ; bic Book Industry Communication::G Reference, information & interdisciplinary subjects::GP Research & information: general ; bic Book Industry Communication::P Mathematics & science ; bic Book Industry Communication::P Mathematics & science::PB Mathematics::PBT Probability & statistics
    Language: English
    Format: application/octet-stream
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