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  • bic Book Industry Communication::M Medicine  (1,180)
  • thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas  (947)
  • Glazialgeologie
  • L22
  • English  (1,596)
  • Spanish  (445)
  • Portuguese  (166)
  • French  (63)
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  • 1
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, recent advancements in the field of pediatric tumors are discussed, and novel prognostic markers are critically appraised. Greater understanding of the heterogeneity of pediatric cancers will ultimately lead to new therapeutic strategies with the potential to provide new prospects for precision medicine in pediatric oncology.
    Keywords: undernutrition ; obesity ; nutritional status ; childhood cancer ; overall survival ; event-free survival ; relapse ; treatment-related toxicity ; review ; sarcoma botryoides ; fertility-sparing surgery ; embryonal rhabdomyosarcoma ; genital tract ; prognosis ; treatment ; local debulking ; neoadjuvant chemotherapy ; radiation ; ovarian cancer ; adolescents ; diagnosis ; therapy ; guidelines ; children ; papillary thyroid cancer ; proto-oncogene B-raf gene (BRAF) ; craniopharyngioma ; recurrence ; risk factors ; youth ; acute lymphoblastic leukemia (ALL) ; child ; genetics ; CDKN2A/2B deletions ; fluorescent in situ hybridization (FISH) ; multiple-ligation probe amplification (MLPA) ; copy-number alterations (CNAs) ; risk stratification ; minimal residual disease (MRD) ; cardiotoxicity ; chemotherapeutics agents ; biomarkers ; omics technology ; medulloblastoma ; tumor ; histologic ; pediatrics ; micro-RNAs ; non-coding RNAs ; molecular subgroup ; stratification ; acute lymphoblastic leukemia ; proteomics ; oncology ; chemotherapy ; cardiac function tests ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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  • 2
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    Taylor & Francis | Routledge
    Publication Date: 2024-04-03
    Description: This volume investigates a galaxy of diverse networks and intellectual actors who engaged in a broad political environment, from conservatism to the most radical right, between the World Wars. Looking beyond fascism, it considers the less-investigated domain of the 'Latin space', which is both geographical and cultural, encompassing countries of both Southern Europe and Latin America. Focus is given to mid-level civil servants, writers, journalists and artists and important 'transnational agents' as well as the larger intellectual networks to which they belonged. The book poses such questions as: In what way did the intellectuals align national and nationalistic values with the project of creating a 'Republic of Letters' that extended beyond each country’s borders, a 'space' in which one could produce and disseminate thought whose objective was to encourage political action? What kinds of networks did they succeed in establishing in the interwar period? Who were these intellectuals-in-action? What role did they play in their institutions’ and cultural associations’ activities? A wider and intricate analytical framework emerges, exploring right-wing intellectual agents and their networks, their travels and the circulation of ideas, during the interwar period and on a transatlantic scale, offering an original contribution to the debate on interwar authoritarian regimes and opening new possibilities for research.
    Keywords: Modern History,Latin American History,Military Regimes,Fascism,Far Right Ideology,Corporatism,Ramiro De Maeztu,Pietro Maria Bardi,Universalist Nationalism,Partido Nacional,Centro De Pesquisa,Primo De Rivera Dictatorship,De La Hispanidad,Je Suis Partout,Fustel De Coulanges,Modern Italian Architecture,Radical Conservative Movements,Lucien Rebatet,UNR,Brazilian Integralism,AIB,La Nueva,Piazza Della Vittoria,Catholic Social Teachings,Young Men,Partido Conservador,Le Corbusier,Du Pin,French Fascism,Charles Maurras,Argentinian Institute ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 3
    Publication Date: 2024-02-05
    Description: In the southern border area, where Ecuador is located with neighboring Peru. There are two important cantons for its commercial passage, the canton Macará in the province of Loja, and the canton Huaquillas in the province of El Oro. Through the Coordination 7 of the Ministry of Public Health, thanks to the ProSalud Frontera Sur Project, the database of the Automated Daily Registry of Consultations and Outpatient Care was managed, which allowed us to clarify the problems at the public health level in these cantons. It can be observed throughout the text that women present a greater number of diseases compared to men, with the latter remaining stable over the three years for both Ecuadorians and foreigners.
    Description: Published
    Description: En la zona fronteriza sur, donde se localiza el Ecuador con el vecino país Perú. Se encuentran dos cantones importantes por su paso comercial, el cantón Macará de la provincia de Loja, y el cantón Huaquillas de la provincia de El Oro. En donde, por medio de la Coordinación 7 del Ministerio de Salud Pública se gestionó gracias al Proyecto ProSalud Frontera Sur, la base de datos Registro Diario Automatizado de Consultas y Atenciones Ambulatorias, que nos permitió clarificar la problemática a nivel de salud pública en estos cantones. Se puede observar a lo largo del texto que las mujeres presentan mayores cantidades de enfermedades frente a los hombres manteniéndose estables estos en los tres años y tanto para ecuatorianos como para extranjeros
    Keywords: bic Book Industry Communication::M Medicine
    Language: Spanish
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  • 4
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    Appalachian State University | Appalachian State University
    Publication Date: 2024-04-02
    Description: Published in 1977, Western North Carolina is a narrative history of the Southern Appalachian Mountains up to 1880. Ora Blackmun depicts the stories of native Cherokee and Sequoyah people and pioneers such as William Bartram, Daniel Boone, Bishops Spangenberg and Asbury, and Zeb Vance.
    Keywords: History ; United States ; State & Local ; South (al, Ar, Fl, Ga, Ky, La, Ms, Nc, Sc, Tn, Va, Wv) ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 5
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Metronomic chemotherapy is now, finally, in clinical use. After 20 years of preclinical development and clinical trials, the emerging data will be of paramount importance in allowing us to assess the impact of metronomic chemotherapy on different tumor types. Indeed, it is likely that the next decade will see a major reassessment of the possible applications of metronomic chemotherapy, both alone and in combination with new therapeutic approaches such as immunotherapies, for the management of cancer. Moreover, the results of clinical trials will likely profoundly affect the direction of the laboratory efforts that are going on in parallel and aiming to improve the personalization of this therapeutic strategy. This Special Issue is our attempt to cover the past and present clinical results that have brought us to this pivotal moment and will form the basis of future clinical developments. Scientists and clinicians caring for cancer patients are well aware of the challenges in dealing with this particular therapeutic approach; one such challenge is obtaining improvements in patient survival without significant toxicity. This edition includes clinical research on chemotherapy and ongoing controversies related to metronomic chemotherapy.
    Keywords: metronomic ; oral cancer ; oral squamous cell carcinoma ; metronomic chemotherapy ; metastatic castration-resistant prostate cancer ; cyclophosphamide ; side effects ; pediatric tumors ; etoposide ; valproic acid ; prostate cancer ; CRPC ; castration ; capecitabine ; paclitaxel ; immunomodulation ; angiogenesis ; microbiome ; breast cancer ; safety ; preclinical studies ; clinical studies ; pharmacokinetic studies ; biomarkers ; chemo-free ; DLBCL ; diffuse-large-b-cell-lymphoma ; elderly ; frail ; comprehensive geriatric assessment ; chemo-endocrine therapy ; FulVEC ; pediatric oncology ; brain tumors ; pharmacology ; medulloblastoma ; ATRT ; immunotherapy ; lymphoma ; vinorelbine ; checkpoint inhibitors ; bic Book Industry Communication::M Medicine
    Language: English
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  • 6
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This collection of articles provides insight into the mental health and nursing care of individuals who are confronting a life-threatening illness. As individuals face a cancer diagnosis, there will be many challenges and changes in their lives. Emotional distress can emerge to greater and lesser degrees. Frequently, these individuals will require additional assistance to cope with the emotional distress they experience. Nurses have an important role in assessing this emotional distress and providing relevant interventions.
    Keywords: Latinx ; family ; meaning ; communication ; coping with advanced cancer ; delirium ; liaison nurse ; misrecognition of delirium ; coordination ; breast cancer ; psychological distress ; quality of life ; women’s health ; qualitative study ; cancer care ; older adults ; mental health ; feeling safe ; home-dwelling ; patients with terminal cancer ; caregivers ; competency in anticipatory grief counseling ; emotional care ; person-centered care ; qualitative research ; anxiety ; depression ; family involvement ; hepatocellular carcinoma ; palliative care ; cancer ; decision-making ; nurse ; caregiving self-efficacy ; family caregiver ; oral cancer ; oncology ; nursing ; clinical nurse specialists ; cancer patients ; expanding nurses’ authority ; professionalization ; policy ; education ; bic Book Industry Communication::M Medicine
    Language: English
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  • 7
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Obstructive sleep apnea is a highly prevalent disorder with strong associations with cardiovascular, cerebrovascular, metabolic, and cognitive consequences, including drowsy driving. Positive Airway Pressure treatment is the first-line therapy for adults with obstructive sleep apnea who are symptomatic. However, many individuals with comorbidities do not report symptoms that are associated with the disorder, and adherence to treatment is poor, especially in individuals with cardiovascular diseases. This reprint contains reviews and original articles that aim to update the current perspectives on the treatment modalities of obstructive sleep apnea to highlight multidisciplinary approaches, personalized treatment strategies, and the identification of the predictors of a patient’s response to treatment, both in the general population and in clinical cohorts.
    Keywords: obstructive sleep apnea (OSA) ; continuous positive airway pressure (CPAP) ; mandibular advancement devices ; upper airway surgery ; drowsy driving ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
    Language: English
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  • 8
    Publication Date: 2024-01-08
    Description: Therapeutic drug monitoring (TDM) has emerged as a useful tool for optimizing biological treatment in patients with inflammatory bowel disease (IBD) and other immune-mediated inflammatory diseases (IMID). Reactive TDM has rationalized the management of primary non-response and secondary loss of response to biologics, while cumulative evidence suggests that proactive TDM is efficacious for optimizing anti-tumour necrosis factor (anti-TNF) therapy in patients with IBD. Proactive TDM can be very useful for optimizing biological therapy in specific IBD populations, such as pregnant women as well as patients with perianal fistulizing Crohn’s disease and acute severe ulcerative colitis who are characterized by high drug clearance. Preliminary data suggest that proactive TDM may also have a role in de-escalating anti-TNF therapy in patients in clinical remission including stopping the immunomodulator when combined with anti-TNF therapy. However, several knowledge gaps and limitations hinder the wide implementation of TDM in clinical practice, including the optimal drug concentration to target the lag time between sampling and results and the lack of harmonization of TDM assays. Recent advances regarding the role of TDM include the use of rapid point-of-care assays and the incorporation of model-informed precision dosing. The aim of this Special Issue is to highlight the clinical utility of TDM and discuss the barriers and recent advances of TDM of biologics in IBD and other IMID.
    Keywords: ulcerative colitis ; Crohn&rsquo ; s disease ; inflammatory bowel disease ; infliximab ; adalimumab ; certolizumab pegol ; golimumab ; vedolizumab ; ustekinumab ; therapeutic drug monitoring ; immunogenicity ; rheumatoid arthritis ; ankylosing spondylitis ; psoriasis ; clearance ; model informed precision dosing ; bic Book Industry Communication::M Medicine
    Language: English
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  • 9
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    Fundação Editora da UNESP | Editora UNESP
    Publication Date: 2024-04-02
    Description: Este livro reúne textos dedicados a compreender experiências sociais provocadas pela modernização levada pela economia cafeeira às cidades do interior paulista, durante a Primeira República. Os textos conectam-se ao trabalho de José Evaldo de Melo Doin, docente que orientou os autores por mais de duas décadas na Faculdade de Ciências Sociais e Humanas da Universidade Estadual Paulista (Unesp), campus de Franca. Melo Doin dedicou-se ao estudo da construção histórica da contemporaneidade, por meio de análises do intricado diálogo entre História, Economia, Ciência Política, Arquitetura e Urbanismo. Nesta obra, fontes diversas – almanaques, fotos, crônicas, jornais, memórias, álbuns, entre outros – são interpretadas para compreender as vivências urbanas construídas com a chegada de tecnologias e hábitos novos, ao mesmo tempo em que traços de antiga sociabilidade e certos limites materiais e técnicos continuam preservados. Assim, Ribeirão Preto, Barretos, Mococa, São Carlos, Rio Claro, Batatais, Santa Bárbara D’Oeste e Franca revelam paisagens e cotidianos dotados de tensões, particularidades, permanências e possibilidades.
    Keywords: History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Portuguese
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  • 10
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    Cornell University Press
    Publication Date: 2024-04-06
    Description: In People's Diplomacy, Kazushi Minami shows how the American and Chinese people rebuilt US-China relations in the 1970s, a pivotal decade bookended by Richard Nixon's 1972 visit to China and 1979 normalization of diplomatic relations. Top policymakers in Washington and Beijing drew the blueprint for the new bilateral relationship, but the work of building it was left to a host of Americans and Chinese from all walks of life, who engaged in "people-to-people" exchanges. After two decades of estrangement and hostility caused by the Cold War, these people dramatically changed the nature of US-China relations. Americans reimagined China as a country of opportunities, irresistible because of its prodigious potential, while Chinese reinterpreted the United States as an agent of modernization, capable of enriching their country and rejuvenating their lives. Drawing on extensive research at two dozen archives in the United States and China, People's Diplomacy redefines contemporary US-China relations as a creation of the American and Chinese people.
    Keywords: people to people, 1970s, Nixon administration, sino-american, Henry Kissinger, Beijing, engagement over isolation, foreign policy ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations::JPSD Diplomacy
    Language: English
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  • 11
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Inflammatory bowel disease (IBD) encompasses chronic idiopathic relapsing and remitting gastrointestinal autoimmune diseases characterized by chronic inflammatory disorders of complex etiology, posing clinical challenges due to their often therapy-refractory nature. The primary disorders within the IBD classification are ulcerative colitis (UC) and Crohn’s disease (CD), sharing similarities but exhibiting distinct differences, sometimes making their discrimination challenging.A prominent feature of IBD is the inflammation of the intestinal mucosa, characterized by the robust and persistent infiltration of immune cells and compromised intestinal barrier integrity, leading to a phenomenon known as “leaky gut.” Inflammation can manifest acutely or chronically, known as relapsing, and can increase in severity over time, thereby causing life-long morbidities and reduced quality of life for affected individuals, underscoring the need for a deeper comprehension of the molecular contributors to disease pathogenesis and progression.
    Keywords: inflammatory bowel diseases ; cell autofluorescence ; immune cells ; NADH ; FAD ; flow cytometry ; multiphoton microscopy ; colitis ; colitis-associated cancer ; inflammatory bowel disease ; colorectal cancer ; colon adenocarcinoma ; ulcerative colitis ; Crohn’s disease ; cDNA microarray ; transciptomics analysis ; microarray ; inflammatory bowel diseases (IBDs) ; vasculature ; angiogenesis ; gut vascular barrier ; vessel permeability ; epithelial barrier ; homeostasis ; acetylcholine ; muscarinic receptor ; non-neuronal acetylcholine ; mucosal wound healing ; ferroptosis ; leaky gut ; inflammatory bowel disease (IBD) ; triple-culture ; Caco-2 ; HT29-MTX-E12 ; THP-1 ; monocyte-derived macrophage ; inflammation ; TEER ; FITC-dextran 4 kDa (FD4) ; pro-inflammatory cytokines ; HIF-1α ; PHD2 ; AKT ; intestinal epithelial cells ; probiotics ; LPS ; antigen-specific T-cells ; celiac disease ; gliadin ; IBD ; food antigens ; intestinal Behcet’s disease ; immune mechanism ; biological agents ; claudin ; tight junctions ; barrier function ; gut ; ZO-1 ; actin ; cell migration ; cell division ; colon cancer ; PMNs ; LDs ; FOXO3 ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 12
    Publication Date: 2024-04-02
    Description: This book presents the transcriptions and annotated translations of fifteen key historical documents concerning the Tapuia indigenous people written just before and during the Dutch occupation of northeastern Brazil. The selected documents vary widely in type, including letters, descriptions, reports, first-person declarations, diaries, and transcripts of interrogations, thereby showcasing different perspectives and audiences. Some of the documents were authored by European writers, while others register indigenous voices somewhat more directly in the form of interviews or declarations. These texts provide important first-hand information about the Tapuia and other indigenous peoples during the Dutch conquest, revealing their cultural practices and knowledge while also detailing their strategic engagements with each other and with different European colonizers.
    Keywords: archives ; Brazil ; colonial Brazil ; indigenous history ; indigenous people ; Tapuia ; West India Company ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 13
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    New York University Press | NYU Press
    Publication Date: 2024-04-04
    Description: From 1944 to 1946, as the world pivoted from the Second World War to an unsteady peace, Americans in more than two hundred cities and towns mobilized to chase an implausible dream. The newly-created United Nations needed a meeting place, a central place for global diplomacy—a Capital of the World. But what would it look like, and where would it be? Without invitation, civic boosters in every region of the United States leapt at the prospect of transforming their hometowns into the Capital of the World. The idea stirred in big cities—Chicago, San Francisco, St. Louis, New Orleans, Denver, and more. It fired imaginations in the Black Hills of South Dakota and in small towns from coast to coast. Meanwhile, within the United Nations the search for a headquarters site became a debacle that threatened to undermine the organization in its earliest days. At times it seemed the world’s diplomats could agree on only one thing: under no circumstances did they want the United Nations to be based in New York. And for its part, New York worked mightily just to stay in the race it would eventually win. With a sweeping view of the United States’ place in the world at the end of World War II, Capital of the World tells the dramatic, surprising, and at times comic story of hometown promoters in pursuit of an extraordinary prize and the diplomats who struggled with the balance of power at a pivotal moment in history.
    Keywords: History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 14
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Recent years have seen growing interest in equine lung and heart health, and advances in technology and a focus on equine welfare have driven this research. This Special Issue explores novel diagnostic and therapeutic approaches, including imaging techniques and lung function testing, immunological features, and immunomodulatory treatments for equine asthma and common racehorse respiratory issues. Moreover, it reports on novel echocardiography data of donkeys. This collection offers valuable insights into equine cardio-respiratory medicine.
    Keywords: equine asthma ; exercise-induced pulmonary hemorrhage ; racehorse respiratory medicine ; donkey cardiology ; bic Book Industry Communication::M Medicine
    Language: English
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  • 15
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on treating the associated comorbidities and complications of cerebral palsy. Increased prescription of technology means that we are treating some comorbidities of cerebral palsy earlier or even pre-emptively. Increased life expectancy, compared with 20 years ago, means that we are also seeing even later complications of cerebral palsy. However, increased access to intensive medical care at home, non-invasive ventilation, and total parenteral nutrition now exist. There is also greater engagement with the perspectives and expectations of parents/carers and children. As society begins to discuss mental health more openly, we are also starting to recognise the significant two-way associations between disability and mental health. Ethical consultation may be warranted when harm with treatment exceeds the benefit. As we prepare children with cerebral palsy for adulthood, there is more thought and discussion around issues such as pain, mental health, quality of life, independence, and participation. Researchers in the field of cerebral palsy have contributed original articles and reviews which help build our evidence base to guide shared decision making.
    Keywords: mental health ; anxiety ; depression ; cerebral palsy ; adolescence ; young adults ; young people ; adolescents ; unmet need ; health services ; physical therapy ; occupational therapy ; fracture ; bone fragility ; mortality ; epidemiology ; age-adjusted mortality rates ; death certificate ; medical education ; severe neurological impairment ; scoliosis ; shared decision-making ; respiratory ; hospitalisations ; antibiotics ; Indigenous ; inequities ; cell therapies ; stem cells ; comorbidities ; outcome measures ; clinical studies ; inflammation ; biomarker ; comorbidity ; scoping review ; co-design ; intervention ; participation ; involvement matrix ; public and patient involvement ; early intervention ; infant vocalisations ; infants ; single-subject research design ; CP ; infant ; stress ; parents ; fathers ; parent–infant interaction ; representations ; epilepsy ; children ; neuroimaging ; seizure outcome ; Sialorrhea ; submandibular duct relocation ; postoperative management ; ultrasound ; piecewise model ; muscle volume ; cross-sectional area ; GMFCS ; upper limb ; sensory function ; bimanual intensive functional therapy ; hand function ; associated impairment ; register ; low- and middle-income country ; hip displacement ; hip surveillance ; adductor-psoas release ; hip reconstruction ; guided growth ; salvage surgery ; disability ; emotion regulation ; atropine ; sialorrhea ; pediatric ; drooling ; sublingual ; developmental disorders ; neurodevelopmental disorders ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 16
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    New York University Press | NYU Press
    Publication Date: 2024-04-07
    Description: Helen Heran Jun explores how the history of U.S. citizenshiphas positioned Asian Americans and African Americans in interlocking socio-political relationships since the mid nineteenth century. Rejecting the conventional emphasis on ‘inter-racial prejudice,’ Jun demonstrates how a politics of inclusion has constituted a racial Other within Asian American and African American discourses of national identity. Race for Citizenship examines three salient moments when African American and Asian American citizenship become acutely visible as related crises: the ‘Negro Problem’ and the ‘Yellow Question’ in the mid- to late 19th century; World War II-era questions around race, loyalty, and national identity in the context of internment and Jim Crow segregation; and post-Civil Rights discourses of disenfranchisement and national belonging under globalization. Taking up a range of cultural texts—the 19th century black press, the writings of black feminist Anna Julia Cooper, Asian American novels, African American and Asian American commercial film and documentary—Jun does not seek to document signs of cross-racial identification, but instead demonstrates how the logic of citizenship compels racialized subjects to produce developmental narratives of inclusion in the effort to achieve political, economic, and social incorporation. Race for Citizenship provides a new model of comparative race studies by situating contemporary questions of differential racial formations within a long genealogy of anti-racist discourse constrained by liberal notions of inclusion.
    Keywords: 19th ; acutely ; African ; American ; around ; Asian ; became ; century ; citizenship ; disenfranchisement ; examines ; globalization ; identity ; II-era ; late ; loyalty ; mid- ; moments ; national ; Negro ; post-Civil ; Problem ; Question ; questions ; race ; Rights ; three ; under ; visible ; when ; World ; Yellow ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSL Ethnic studies ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 17
    Publication Date: 2024-04-02
    Description: Since antiquity, knowledge has often been juxtaposed with opinion. Whereas opinion commonly refers to subjective perceptions and viewpoints, knowledge is typically intended to represent objective and verifiable propositions. On this view, knowledge per se claims a universal dimension in that it pretends to be approvable through the reason of everyone, everywhere. This universal aspect of the concept of knowledge stands in marked contrast to cultures of local knowledge, where the generation of knowledge is dependent on specific times and places. These divergent aspects came into conflict when Indigenous knowledge was contested by Europeans and likewise, Indigenous challenges to European knowledge occurred. Based on religious, linguistic, demographic, and cultural disparities, knowledge operative in one context was adapted, manipulated, reframed, or dismissed as spurious or heretical in another framework. This book focuses on historical examples of Indigenous knowledge from 1492 until circa 1800, with contributions from the fields of history, art history, geography, anthropology, and archaeology.
    Keywords: Indigenous knowledge ; early modern period ; the Americas ; historiography ; material studies ; transfer of knowledge ; globalisation ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English , Spanish
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  • 18
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint entails descriptions of novel issues and challenges for primary mental healthcare regarding both general and vulnerable populations on a global scale. It is intended for health professionals and all who are interested in mental health care at the primary level.
    Keywords: depression ; sense of coherence ; burnout ; COVID-19 ; nurses ; medication adherence ; mental health nurses ; tacit knowledge ; schizophrenia ; sensory processing sensitivity ; environmental sensitivity ; university students ; nursing ; scale ; somatization ; number of diseases ; coping strategies ; sex ; aggression ; alexithymia ; comprehensibility ; quality of life ; family caregivers ; students ; medical ; psychological problem ; undergraduate ; Saudi Arabia ; n/a ; prospect theory ; applied psychology ; health ; decision making ; behavior ; prevention ; multiple sclerosis ; Beck depression inventory ; anxiety ; fatigue ; mediation ; lawyers ; suicidal ideation ; occupational stress ; loneliness ; perceived stress ; mental health ; work overcommitment ; mental health care ; adolescence ; internalizing/externalizing problems ; social skills ; neurodevelopmental disorders ; filmmaking intervention ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
    Language: English
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  • 19
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint includes studies on diagnosing, evaluating and managing the pathologies diagnosed during pregnancy. The information provided in these pages is helpful for specialists in obstetrics and gynaecology but also for other medical specialities involved in treating pregnant women with associated pathologies. Studying the articles in the reprint could contribute to improving case management.
    Keywords: pregnancy ; fetus prenatal care ; high-risk ; pathology ; bic Book Industry Communication::M Medicine
    Language: English
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  • 20
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    New York University Press | NYU Press
    Publication Date: 2024-04-07
    Description: The murky history behind municipal laws criminalizing disability In the late-nineteenth and early-twentieth centuries, municipal laws targeting "unsightly beggars" sprang up in cities across America. Seeming to criminalize disability and thus offering a visceral example of discrimination, these “ugly laws” have become a sort of shorthand for oppression in disability studies, law, and the arts. In this watershed study of the ugly laws, Susan M. Schweik uncovers the murky history behind the laws, situating the varied legislation in its historical context and exploring in detail what the laws meant. Illustrating how the laws join the history of the disabled and the poor, Schweik not only gives the reader a deeper understanding of the ugly laws and the cities where they were generated, she locates the laws at a crucial intersection of evolving and unstable concepts of race, nation, sex, class, and gender. Moreover, she explores the history of resistance to the ordinances, using the often harrowing life stories of those most affected by their passage. Moving to the laws’ more recent history, Schweik analyzes the shifting cultural memory of the ugly laws, examining how they have been used—and misused—by academics, activists, artists, lawyers, and legislators.
    Keywords: Americas ; chapter ; hard ; history ; look ; ugly ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 21
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    University of Nebraska Press
    Publication Date: 2024-04-02
    Description: Amazonian Cosmopolitans focuses on the autobiographical accounts of two Brazilian Indigenous leaders, Prepori and Sabino, Kawaiwete men whose lives spanned the twentieth century, when Amazonia increasingly became the context of large-scale state projects. Both give accounts of how they worked in a range of interethnic enterprises from the 1920s to the 1960s in central Brazil. Prepori, a shaman, also gives an account of his relations with spirit beings that populate the Kawaiwete cosmos as he participated in these projects. Like other Indigenous Amazonians, Kawaiwete value engagement with outsiders, particularly for leaders and shamanic healers. These social engagements encourage a careful watching and learning of others’ habits, customs, and sometimes languages, what could be called a kind of cosmopolitanism or an attitude of openness, leading to an expansion of the boundaries of community. The historical consciousness presented by these narrators centers on how transformations in social relations were experienced in bodily terms—how their bodies changed as new relationships formed. Amazonian Cosmopolitans offers Indigenous perspectives on twentieth-century Brazilian history as well as a way to reimagine lowland peoples as living within vast networks, bridging wide social and cosmological divides.
    Keywords: History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The aim of this Special Issue is to specify relevant principles of mathematics and mechanics in order to explore and understand biological problems. We summarize the most important parameters that influence human performance and that are related to the health sciences for all age groups, throughout their lives. We present papers that aim to introduce the latest research in the fields of health, quality-of-life improvement, and sport rehabilitation and that summarize their recommendations for best practice. The aim for this Special Issue is, therefore, to effectively combine and coordinate research and results in order to understand and improve human movement in medicine, sports, and at work.
    Keywords: tendinopathy ; Achilles tendon ; hyaluronic acid ; viscoelastic properties ; isometric contraction ; matrix metalloproteinase 3 ; interleukin-1beta ; fascia ; chronic low back pain ; myofascial release ; quality of life ; older adults ; oldest-old ; measurement invariance ; SHARE European Survey ; therapeutic exercises ; chronic neck pain ; scapular dyskinesia ; DOMS ; vibration ; post-exercise muscle damage ; physical exercise ; recovery ; women’s rugby ; anthropometry ; body composition ; adiposity ; somatotype ; lower-body strength ; accelerometry ; falls ; squat jump ; syndesmosis ; anterior inferior tibiofibular ligament ; high ankle sprain ; rotational instability ; posterior malleolus ; stabilization ; anatomic repair ; syndesmotic screw ; suture-button ; internal bracing ; treatment algorithm ; cardiac rehabilitation ; peripheral artery disease ; COVID-19 ; intermittent claudication ; review ; pressotherapy ; compression ; regeneration ; return-to-play ; rotator cuff repair ; shoulder injuries ; shoulder surgery ; shoulder assessment ; chronic obstructive pulmonary disease ; COPD ; acupuncture ; acupuncture therapy ; acupuncture treatment ; health-related quality of life ; anterior knee laxity ; stiffness ; general joint laxity ; genu recurvatum ; low back pain ; physical activity ; trunk alignment ; rasterstereographic system ; young males ; tissue flossing ; floss band ; vascular occlusion ; muscle strength ; muscle endurance ; warm-up ; TECAR therapy ; high-intensity laser therapy ; manual therapy ; muscle disorders ; hemophilia ; knee ; virtual reality exposure therapy ; joint pain ; physiotherapy ; daily physical function ; middle-aged and older adults ; CHARLS ; aging ; appendicular muscle mass ; inflammaging ; biomarkers ; adiponectin ; sarcopenia ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The 3D analysis of human movement aims to objectively and quantitatively assess motor functions and alterations. It is a valuable method for sport scientists, coaches, and clinicians to evaluate sport performance, common movements, and alterations. The feasibility of 3D analysis is increasing because it can be adopted both in a laboratory setting or directly in the field, in static or dynamic conditions, and for physiological or pathological movements. This evaluation technique can be adopted for many people, including children, adolescents, adults, and older people, whether they are sedentary or athletes and whether they are healthy or motor-impaired people.
    Keywords: virtual reality ; augmented reality ; lifelogging ; mirror world ; health ; posture training ; feedback ; COVID-19 ; neck-shoulder-region ; shoulder protraction ; upper crossed syndrome ; posture weakness ; physical inactivity ; sedentary behavior ; soccer ; climbing ; exhaustion ; fatigue ; training ; machine learning ; sports ; gender ; data mining ; artificial intelligence ; posture ; reproducibility ; mobile app ; movement ; kinesiology ; sport performance ; inertial sensor ; inertial sensor device ; inertial measurement unit ; training load ; external load ; physical demand ; handstand ; postural control ; postural balance ; sEMG ; stabilometric assessment ; exercise ; Nordic walking ; walking ; 3D kinematics ; biomechanics ; gait analysis ; kyphosis ; spinal mouse ; photogrammetry ; postural evaluation ; bicycle ; cyclists ; saddle pressure ; perineal pressure ; urogenital system ; injury prevention ; cervical ROM ; elastic taping ; neck pain ; musculoskeletal health ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 24
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In the orthopedic surgical field, knee surgeries, including articular cartilage repair procedures, meniscus surgery, ligament reconstruction surgery, osteotomy surgery, and partial/total knee arthroplasty surgery, have made great advances over the last few decades. This Special Issue highlights and focuses on the surgical concepts and techniques, decision-making processes, perioperative management protocols, and clinical outcomes of the recent various advanced knee surgery procedures.
    Keywords: high tibial osteotomy ; TomoFix ; plate position ; anatomical conformity ; dual-energy CT ; Hounsfield unit ; bone mineral density ; volumetric phantomless BMD ; opportunistic CT ; orthopedic surgeon ; planning ; survey ; total knee arthroplasty ; unicompartmental knee arthroplasty ; anterior cruciate ligament ; reconstruction ; bone tunnel widening ; adjustable-loop device ; interference screw ; hamstring tendon ; autograft ; tibial component alignment ; radiographic references ; extramedullary system ; tranexamic acid ; clamping time ; transfusion ; estimated blood loss ; continuous cold flow therapy ; cryotherapy ; pain ; opioids consumption ; patient satisfaction ; bone marrow lesion ; knee ; meniscus ; root tear ; root repair ; femorotibial joint ; chondromalacia ; aging ; body mass index ; magnetic resonance imaging ; automated detection ; detection algorithm ; deep learning ; venous thromboembolism ; medial collateral ligament ; strain ; video extensometer ; medial opening-wedge high tibial osteotomy ; central sensitization ; patient-reported outcomes ; osteotomy site pain ; minimal clinically important difference ; human umbilical cord blood derived mesenchymal stem cells ; cartilage regeneration ; cartilage repair ; osteoarthritis treatment ; stem cell therapy ; Outerbridge ; degeneration ; spacer block ; intramedullary rod ; femorotibial congruence ; unicompartmental arthroplasty ; osteoarthritis ; cartilage ; stem cells ; umbilical cord blood ; femur fracture ; polyethylene insert ; osteoporosis ; multivariate logistic analysis ; atelocollagen ; microfracture ; ACIC ; bone marrow aspirate concentrate ; human umbilical cord blood-derived mesenchymal stem cells ; knee osteoarthritis ; loosening ; arthroplasty ; machine learning ; transfer learning ; review ; prosthesis ; meniscus root ; medial meniscus posterior root ; medial meniscus posterior root tear ; meniscus root repair ; transtibial pull-out repair ; bone tunnel enlargement ; anterior cruciate ligament reconstruction ; landmark ; lateral tibial spine ; anatomy ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Over the years, digestive endoscopy has gone through a revolution. With different technological improvements, its diagnostic role is indeed becoming more and more sophisticated and is even moving closer to pathological evaluation. Above all, its therapeutic purpose is to date the first line of treatment for several gastrointestinal diseases. Importantly, the role of digestive endoscopy is also crossing over the mere concept of the GI tract and digestive diseases and will probably find a place in a more holistic concept of health. In this Special Issue, several emerging techniques are addressed, highlighting how endoscopy is emerging as a minimally invasive treatment procedure for several gastrointestinal diseases and post-surgical complications. However, crucial to this is the safety of all endoscopic processes, starting from endoscopic suites to the management of intra- and post-procedural complications.
    Keywords: interventional endoscopy, ERCP, cholangioscopy, biliopancreatic endoscopy, CH-EUS, radiofrequency ablation, necrosectomy, locoregional treatment, bariatric endoscopy, artificial intelligence ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Modern medical imaging systems provide information about the patient's health condition. Their precision, resolution and sensitivity are increasing, and new possibilities of differentiating the condition of tissue are constantly appearing. These advances are also taking place in musculoskeletal imaging. Increasingly accurate imaging in various modalities allows us to discover new relationships between the image and the diagnosis. It is therefore important to use all this information to best serve the patient. That is why research related to the analysis of medical images is so important, because it allows us to indicate what is invisible to the naked eye or to quantify what has so far been measured by humans or subject to discretionary assessment. This collection includes 25 works related to the analysis of images created during diagnostics of the musculoskeletal system using various modalities—from X-ray and fluoroscopy to conventional or spectral computed tomography, magnetic resonance imaging, ultrasound, elastography, PET/CT and systems for analyzing patient mechanics. Research was carried out related to the detection of various conditions, parameterization of clinical and population phenomena, and detection of image–clinical condition relationships. Despite the current popularity of machine learning techniques, the collection is dominated by classic engineering methods related to image processing. Several works use textural analysis, which has not been appreciated so far, which is particularly related to the imaging of the structure, especially of bones.
    Keywords: bone imaging, musculoskeletal imaging, image processing, image analysis, segmentation, textural analysis, machine learning ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Pain biomarkers are biological indicators or measurable characteristics that can provide information about the presence, severity, or underlying mechanisms of pain. They are valuable for several reasons: Diagnosis and differential diagnosis: Biomarkers can help in the diagnosis of various pain conditions and differentiate between different types of pain, such as neuropathic, inflammatory, or nociceptive pain. This can lead to more accurate and timely diagnoses, which in turn can improve patient care. Monitoring treatment efficacy: Pain biomarkers can be used to track how well treatments are working for individuals suffering from chronic pain conditions. This allows healthcare providers to make informed decisions about adjusting treatment plans, optimizing pain management, and avoiding unnecessary or ineffective interventions. Drug development and testing: Biomarkers play a crucial role in the development of new pain medications and therapies. They can help researchers identify potential drug targets, screen compounds for their pain-relieving properties, and assess the safety and efficacy of experimental treatments in clinical trials. Personalized medicine: Pain biomarkers may, in a future, contribute to treatments, tailored to an individual's unique genetic and biological disposition. Reducing opioid misuse: By using biomarkers to assess pain and treatment responses, healthcare providers can make more informed decisions about opioid prescriptions, potentially reducing the overuse and abuse of these medications.
    Keywords: analgesia ; biomarker ; CSF ; cytokine ; inflammation ; neuropathy ; neurotransmitter ; pain ; QoL ; sensitization ; sensory ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    Duke University Press | Duke University Press Books
    Publication Date: 2024-04-02
    Description: In this environmental history of twentieth-century Mexico, Christopher R. Boyer conceptualizes the forests of Chihuahua and Michoacán as political landscapes. Conflicts among local landowners, the federal government and timber companies politicized these geographies, demonstrating the crucial role that social forces play in the construction of environments.
    Keywords: History of the Americas; Conservation of the environment ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::R Earth Sciences, Geography, Environment, Planning::RN The environment::RNK Conservation of the environment
    Language: English
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    New York University Press | NYU Press
    Publication Date: 2024-04-07
    Description: As banks crashed, belts tightened, and cupboards emptied across the country, American prisons grew fat. Doing Time in the Depression tells the story of the 1930s as seen from the cell blocks and cotton fields of Texas and California prisons, state institutions that held growing numbers of working people from around the country and the world—overwhelmingly poor, disproportionately non-white, and displaced by economic crisis. Ethan Blue paints a vivid portrait of everyday life inside Texas and California’s penal systems. Each element of prison life—from numbing boredom to hard labor, from meager pleasure in popular culture to crushing pain from illness or violence—demonstrated a contest between keepers and the kept. From the moment they arrived to the day they would leave, inmates struggled over the meanings of race and manhood, power and poverty, and of the state itself. In this richly layered account, Blue compellingly argues that punishment in California and Texas played a critical role in producing a distinctive set of class, race, and gender identities in the 1930s, some of which reinforced the social hierarchies and ideologies of New Deal America, and others of which undercut and troubled the established social order. He reveals the underside of the modern state in two very different prison systems, and the making of grim institutions whose power would only grow across the century.
    Keywords: History of the Americas ; Crime and criminology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKV Crime and criminology
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    De Gruyter | De Gruyter Oldenbourg
    Publication Date: 2024-04-02
    Description: Western expansion in North America has mainly been described as either a linear sequence energized by nineteenth-century nation-building processes at a moving frontier, or as the practice of settler colonialism and its exploitation of resources and displacement of nonwhite peoples. This book suggests that shifting the focus from this binary pattern towards spatial imaginations and spatialization processes—a new theoretical framework developed at SFB 1199—provides novel insights into the placemaking dynamics of the American West. It brings to light a discursive diversity that often contradicts unidirectional interpretive patterns. It becomes clear that while some discourses solidified into spatial metanarratives like the character-shaping clash of civilizations at the frontier or manifest destiny, alternative spatial imaginations exist juxtaposed to or obfuscated by canonical interpretations. Making use of a variety of sources (including works of literature, poetry, newspapers, paintings, and speeches) to access spatialization processes on several sociocultural scales, the book presents a careful exploration of the parameters that inform(ed) the creation, affirmation, and subversion of spatial imagination of the American West throughout the nineteenth century from the perspective of American Studies.
    Keywords: thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue focuses on the comprehensive understanding and novel treatments in the realm of cornea and ocular surface diseases. Ranging from the relatively benign manifestations of keratoconjunctivitis sicca to more critical conditions such as corneal ulcers, ocular surface diseases pose a considerable challenge in clinical ophthalmology. Such conditions can severely compromise the transparency of the cornea, often necessitating interventions such as keratoplasty. A significant emphasis of this edition is on the paramount importance of pre-surgical optimization. A successful keratoplasty is often predicated on the health of the ocular surface. Through a series of insightful articles, the importance of enhancing tear function, rehabilitating the normal lid anatomy, and ensuring a robust limbal stem cell supply is elucidated. Properly addressing these factors has a direct bearing on the success rate of the subsequent surgical intervention. Another highlight of this Special Issue is the presentation of cutting-edge treatments. Researchers from around the globe share their findings, detailing advancements in both surgical and non-surgical treatments. These range from innovative surgical techniques and tools to groundbreaking pharmaceutical agents that hold promise in managing and possibly reversing some of these conditions. In summary, this Special Issue serves as a repository of the latest knowledge in the management of cornea and ocular surface diseases, aimed at both the seasoned ophthalmologist and budding researchers in the field.
    Keywords: cornea ; ocular surface disease ; dry eye ; corneal ulcer ; keratoplasty ; bic Book Industry Communication::M Medicine
    Language: English
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    New York University Press | NYU Press
    Publication Date: 2024-04-04
    Description: On Friday nights many parents want to have a little fun together—without the kids. But “getting a sitter”—especially a dependable one—rarely seems trouble-free. Will the kids be safe with “that girl”? It’s a question that discomfited parents have been asking ever since the emergence of the modern American teenage girl nearly a century ago. In Babysitter, Miriam Forman-Brunell brings critical attention to the ubiquitous, yet long-overlooked babysitter in the popular imagination and American history. Informed by her research on the history of teenage girls’ culture, Forman-Brunell analyzes the babysitter, who has embodied adults’ fundamental apprehensions about girls’ pursuit of autonomy and empowerment. In fact, the grievances go both ways, as girls have been distressed by unsatisfactory working conditions. In her quest to gain a fuller picture of this largely unexamined cultural phenomenon, Forman-Brunell analyzes a wealth of diverse sources, such as The Baby-sitter’s Club book series, horror movies like The Hand That Rocks the Cradle, urban legends, magazines, newspapers, television shows, pornography, and more. Forman-Brunell shows that beyond the mundane, understandable apprehensions stirred by hiring a caretaker to “mind the children” in one’s own home, babysitters became lightning rods for society’s larger fears about gender and generational change. In the end, experts’ efforts to tame teenage girls with training courses, handbooks, and other texts failed to prevent generations from turning their backs on babysitting.
    Keywords: American ; babysitter ; faces ; many ; mini-mother ; Teenaged ; temptress ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
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    New York University Press | NYU Press
    Publication Date: 2024-04-07
    Description: In As Long as We Both Shall Love, Karen M. Dunak provides a nuanced history of the American wedding and its celebrants. Blending an analysis of film, fiction, advertising, and prescriptive literature with personal views from letters, diaries, essays, and oral histories, Dunak demonstrates the ways in which the modern wedding epitomizes a diverse and consumerist culture and aims to reveal an ongoing debate about the power of peer culture, media, and the marketplace in America.
    Keywords: History of the Americas ; Gender studies, gender groups ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSF Gender studies, gender groups
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    Taylor & Francis | Intellectuals in the Latin Space during the Era of Fascism | Routledge
    Publication Date: 2024-04-02
    Description: This volume investigates a galaxy of diverse networks and intellectual actors who engaged in a broad political environment, from conservatism to the most radical right, between the World Wars. Looking beyond fascism, it considers the less-investigated domain of the 'Latin space', which is both geographical and cultural, encompassing countries of both Southern Europe and Latin America. Focus is given to mid-level civil servants, writers, journalists and artists and important 'transnational agents' as well as the larger intellectual networks to which they belonged. The book poses such questions as: In what way did the intellectuals align national and nationalistic values with the project of creating a 'Republic of Letters' that extended beyond each country’s borders, a 'space' in which one could produce and disseminate thought whose objective was to encourage political action? What kinds of networks did they succeed in establishing in the interwar period? Who were these intellectuals-in-action? What role did they play in their institutions’ and cultural associations’ activities? A wider and intricate analytical framework emerges, exploring right-wing intellectual agents and their networks, their travels and the circulation of ideas, during the interwar period and on a transatlantic scale, offering an original contribution to the debate on interwar authoritarian regimes and opening new possibilities for research.
    Keywords: Universalist Nationalism,Fustel De Coulanges,Partido Nacional,Pietro Maria Bardi,Ramiro De Maeztu,Centro De Pesquisa,Primo De Rivera Dictatorship,Je Suis Partout,De La Hispanidad,Traditionalist Nationalism,Modern Italian Architecture,Filipe II,Radical Conservative Movements,Alfonso XIII,UNR,AIB,Dominant Historical Narrative,Spanish Intellectuals,Le Corbusier,Superimposing,Pietro,Muñoz,Unamuno ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
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    Publication Date: 2024-01-08
    Description: This reprint, entitled “Management of Acute and Chronic Complications of Lysosomal Storage Diseases in Children and Adults: Current Practice and Future Opportunities”, covers broad aspects of this group of rare diseases. The first theme includes articles on the management of pain, corneal clouding, gastrointestinal and airway diseases in Mucopolysaccharidoses and Mucolipidoses, and the evaluation of dysphonia in Pompe disease. Additionally, attention deficit and ADHD and the management of atherosclerosis in Fabry disease are considered here. The second theme includes diagnostic conundrums in lysosomal storage diseases, e.g., the prenatal diagnosis of Gaucher disease during pregnancy, the diagnosis of secondary hyperparathyroidism in Mucolipidoses, and the application of the new biomarker “plasma neurofilament light” in Niemann Pick C disease, as well as the correlation of enzyme activity with molecular diagnosis in Pompe disease. The articles in the third theme describe the impact of therapies on clinical outcomes. For example, a systematic review of the impact of enzyme replacement therapy on late-onset Pompe disease and trehalose use on Niemann Pick A and B is included. The remaining articles describe the NHS processes for overcoming challenges resulting from the COVID-19 pandemic and the differences in the transition from paediatric to adult services between different countries.
    Keywords: Mucopolysaccharidosis ; corneal clouding ; penetrating keratoplasty ; deep anterior lamellar keratoplasty ; mucopolysaccharidoses ; airway ; obstruction ; management ; Fabry disease ; attention ; Attention Deficit/Hyperactivity ; cognition ; late-onset Pompe disease ; gastrointestinal ; smooth muscles ; PROMIS–GI symptom scales ; GAAKO mice ; glycogen storage disorder ; translational research ; patient-reported outcomes measures ; mucopolysaccharidosis ; MPS ; disease manifestations ; symptoms ; morbidity ; spine disease ; anaesthesia ; perioperative complications ; surgery ; pompe disease ; speech ; voice ; dysphonia ; acoustic ; auditory-perceptual ; GRBAS ; respiratory ; Pompe disease ; gene panel sequencing ; alpha-glucosidase ; GAA ; dried-blood spots ; fabry disease ; neuropathic pain ; depression ; Fabry ; atherosclerosis ; ischaemia ; perfusion ; angina ; Sanfilippo syndrome ; mortality ; Niemann–Pick C ; neurofilament light ; biomarkers ; neurological disease ; glycogen storage disease type II ; enzyme replacement therapy ; COVID-19 ; inherited metabolic disorders ; rare autoinflammatory diseases ; health care providers ; Gaucher disease ; NIHF ; perinatal-lethal Gaucher disease ; PLGD ; ichthyosis ; GBA gene ; airway management ; radiology ; hyoid bone ; chin ; intubation ; intratracheal ; lysosomal storage disease (LSD) ; Niemann–Pick type A ; Niemann–Pick type B ; acid sphingomyelinase ; sphingolipid deposition ; trehalose ; mucolipidosis type II ; ML II ; I-cell disease ; hyperparathyroidism ; mucolipidosis ; ML ; MLII ; transition service ; adult metabolic medicine ; collaboration ; challenges ; inherited metabolic diseases ; healthcare systems ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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    New York University Press | NYU Press
    Publication Date: 2024-04-03
    Description: Cool. The concept has distinctly American qualities and it permeates almost every aspect of contemporary American culture. From Kool cigarettes and the Peanuts cartoon's Joe Cool to West Side Story (Keep cool, boy.) and urban slang (Be cool. Chill out.), the idea of cool, in its many manifestations, has seized a central place in our vocabulary. Where did this preoccupation with cool come from? How was Victorian culture, seemingly so ensconced, replaced with the current emotional status quo? From whence came American Cool? These are the questions Peter Stearns seeks to answer in this timely and engaging volume. American Cool focuses extensively on the transition decades, from the erosion of Victorianism in the 1920s to the solidification of a cool culture in the 1960s. Beyond describing the characteristics of the new directions and how they altered or amended earlier standards, the book seeks to explain why the change occurred. It then assesses some of the outcomes and longer-range consequences of this transformation.
    Keywords: History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Molecular toxicology is a field that investigates the interactions between chemical or biological molecules and organisms at the molecular level. In this Special Issue, we focus on the toxic effects and mechanisms of action of chemical and biological molecules, will be of great interest of readers in molecular toxicology and applied pharmacology.
    Keywords: smoking ; inflammatory ; cytokine ; human serum ; GO ; PRRSV ; FT-SPR ; sensitization ; NNK ; nicotine ; cytotoxicity ; genotoxicity ; cytochrome P450 2A13 ; Aspergillus flavus ; aflatoxins B1 ; carcinogen ; Surface-Enhanced Raman Scattering ; colloidal Au nanoparticles ; portable Raman spectrometer ; Euphorbia semen ; Euphorbia factors ; transcriptome ; RNA sequencing ; bioinformatics ; gene structure ; neuroblast differentiation-associated protein AHNAK ; hepatocellular carcinoma (HCC) ; insulin-like growth factor 1 receptor (IGF-1R) ; interactome ; field cancerization ; 8–17 DNAzyme ; gene silencing ; catalysis ; antisense ; chemical modifications ; 6-cyclohexyl methyl-β-D-maltoside ; transduction efficiency ; conditionally replicative adenovirus ; lethal effect ; gene therapy ; PBDE ; immunotoxicity ; macrophage ; reactive oxygen species ; apoptosis ; immune function ; breast cancer ; signature ; aging ; cancer ; nomogram ; immunotherapy ; tumor mutation burden ; doxorubicin ; Toll-like receptor 4 ; cardiotoxicity ; heart ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology::MMGT Medical toxicology
    Language: English
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    Springer Nature | Palgrave Macmillan
    Publication Date: 2024-04-03
    Description: This open access book investigates how representation of Native Americans and Mexican-origin im/migrants takes place in high school history textbooks. Manually analyzing text and images in United States textbooks from the 1950s to 2022, the book documents stories of White victory and domination over Black, Indigenous, and People of Color (BIPOC) groups that disproportionately fill educational curricula. While representation and accurate information of non-White perspectives improves over time, the same limited tropes tend to be recycled from one textbook to the next. Textual analysis is augmented by focus groups and interviews with BIPOC students in California high schools. Together, the data show how misrepresentation and absence of BIPOC perspectives in textbooks impact youth identity. This book argues for an innovative rethinking of US history curricula to consider which stories are told, and which perspectives are represented.
    Keywords: Secondary Schooling ; Childhood Education ; History Curriculum ; US History ; K-12 Textbooks ; Mexican American representation ; Native American representation ; Textbook representation ; Textbook analysis ; Misrepresentation ; thema EDItEUR::J Society and Social Sciences::JN Education::JND Educational systems and structures::JNDG Curriculum planning and development ; thema EDItEUR::J Society and Social Sciences::JN Education ; thema EDItEUR::J Society and Social Sciences::JN Education::JNF Educational strategies and policy ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JP Politics and government
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: In this Special Issue, we have gathered high-level research papers from all over the world. We would like to thank all researchers for their commitment to the field. From diagnostic ultrasound of different fetal conditions to advanced cardiovascular imaging leading to fetal MRI and from serum markers and biomarkers in maternal and fetal conditions to new modalities in fetal therapy, this Special Issue covers a large scale view of the present spectrum of modern perinatal medicine. Again, a warm thank you to all contributors.
    Keywords: fetal echocardiography ; fetal abnormalities ; fetal therapy ; genetic testing, prenatal medicine ; bic Book Industry Communication::M Medicine
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The topics covered in this Special Issue range from breastfeeding and early-life nutrition to effects on microbiota, infection, allergy, asthma, and the mechanisms of immunomodulation via (the early introduction of) nutrition on infections and the development of (food) allergies.
    Keywords: diet ; pregnancy ; cord blood ; fatty acids ; n-3 PUFAs ; n-6 PUFAs ; arachidonic acid ; phospholipids ; atopic eczema ; NICE birth cohort ; multi-allergen ; early introduction ; food allergy ; safety ; efficacy ; prevention ; allergic sensitization ; foetal immune ontogeny ; gene/environment interactions ; asthma ; eczema ; maternal diet ; PUFAs ; vitamin D ; Mediterranean diet ; microbiome ; breastfeeding ; functional gastrointestinal disorder ; partial hydrolysate ; peptide ; protein ; infancy ; childhood ; immune development ; probiotic ; microbiota ; allergy ; atopic dermatitis ; breastmilk ; house dust mite ; Der p 1 ; Asthma ; total IgE ; atopy ; sensitization ; oral tolerance ; early food introduction ; milk protein ; cow’s milk allergy (CMA) ; maternal atopy ; epigenetics ; pediatric asthma ; cohort study ; immune complex ; trained immunity ; RSV ; bovine IgG ; preF protein ; cow’s milk allergy ; allergen ; hypoallergenic infant formula ; n/a ; IgA deficiency ; selenium deficiency ; zinc deficiency ; recommended dietary allowances ; immune system ; allergen molecules ; milk allergen micro-array ; peptides ; anaphylaxis ; milk tolerance ; diagnosis ; IgE sensitization ; children ; bic Book Industry Communication::M Medicine
    Language: English
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    University of Ottawa Press / Les Presses de l’Université d’Ottawa
    Publication Date: 2024-05-09
    Description: Is the history of Laurentian seigneuries the offspring of political conflict? This question, and many others, are among those addressed in Le féodalisme dans la vallée du Saint-Laurent. In this work, Sanfilippo summarizes and analyzes 250 years (1763–2008) of historiographical production in French and English Canada that deals with the Laurentian seigneurial regime. But the goal of the book is also to put the historians’ discourses on the seigneurial regime back into their respective political contexts. By doing so, the author firmly demonstrates how the history of this regime is inextricably linked to Canadian political dynamics. The result of an objective look by an Italian historian who studied English and French works for many years, Le féodalisme dans la vallée du Saint-Laurent is also a unique essay in the Canadian historiographical landscape now translated into French. At a time of clear revival in seigneurial history, readers will discover the captivating story of Laurentian seigneuries and encounter Sanfilippo’s opinions. The postface, written by Olivier Guimond and Arnaud Montreuil, pursues Sanfilippo’s reflections from 2008 to today.
    Description: L’histoire de la seigneurie laurentienne est-elle la fille du conflit politique ? C’est, entre autres, à cette question que répond Le féodalisme dans la vallée du Saint-Laurent : un problème historiographique. Dans cet ouvrage, Matteo Sanfilippo résume et analyse 250 années (1763-2008) de production historiographique au Canada français et au Canada anglais portant sur le régime seigneurial laurentien. Sanfilippo remet dans leur contexte historique les discours et les débats sur ce régime, qui sont inextricablement liés aux dynamiques politiques canadiennes. Le féodalisme dans la vallée du Saint-Laurent est un essai unique dans le paysage historiographique canadien. Il est ici traduit en français pour la première fois. À l’heure d’un renouveau certain de l’histoire seigneuriale laurentienne, lectrices et lecteurs pourront découvrir les enjeux complexes de son écriture en faisant la rencontre de la pensée originale de Matteo Sanfilippo. Enfin, les historiens Olivier Guimond et Arnaud Montreuil signent une postface dans laquelle ils poursuivent les réflexions de Matteo Sanfilippo entre 2008 et aujourd’hui.
    Keywords: Féodalisme;Régime seigneurial;Canada;Québec;Vallée du Saint-Laurent;Histoire seigneuriale;Seigneurie laurentienne;Histoire des Laurentides ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: French
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Helicobacter pylori is one of the most common infections in the world, affecting roughly half of all humans. Although it is not an infection that causes death immediately after infection, it is one of the largest emerging infectious diseases in the history of humankind, causing a wide variety of diseases and, in the long term, serious complications such as stomach cancer. This Reprint contains empirical studies and reviews regarding the diagnosis, treatment, complications, and management of H. pylori infection, including new diagnostic methods, effective eradication regimens, the management of gastric cancer, and other topics.
    Keywords: gastric cancer ; biliopancreatic reflux ; gastritis ; carcinoma ; endoscopic surveillance ; Helicobacter pylori infection ; gastric stump cancer ; Helicobacter pylori ; H. pylori ; rifabutin ; treatment ; eradication failure ; culture ; bismuth ; rescue ; Hp-EuReg ; third-generation ultrathin endoscope ; transnasal endoscopy ; narrow-band imaging ; Kyoto classification of gastritis ; gastric atrophy and intestinal metaplasia ; diagnosis ; stool antigen test ; urea breath test ; peptic ulcer disease ; triple therapy ; vonoprazan ; dyspepsia ; Kyoto Classification of Gastritis ; cagA ; Okinawa ; endoscopic findings ; Helicobacter infection ; tetracycline ; eradication ; penicillin allergy ; furazolidone ; metronidazole ; amoxicillin ; child ; host genetic factor ; iron deficiency anemia ; iron demand ; iron uptake ; sports activity ; virulence factor ; gastric lymphoma ; MALT lymphoma ; radiotherapy ; chemotherapy ; rituximab ; dual therapy ; vonoprazan (VPZ) ; amoxicillin (AMOX) ; clarithromycin (CAM) ; bic Book Industry Communication::M Medicine
    Language: English
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  • 43
    Publication Date: 2024-02-27
    Description: Collective monograph contains the results of scientific research devoted to new views and proposals for the diagnosis of certain diseases. The proposed solutions are important for clinical practice and inspire optimism in obtaining encouraging results in overcoming some pathologies. Chapter 1 is dedicated to endoscopic retrograde cholangiopancreatography - a contrast study of the bile ducts and ductal system of the pancreas, which is achieved by their cannulation with the help of a flexible endoscope and their visualization by X-ray (fluoroscopy). Thanks to this, it becomes possible to diagnose and perform medical interventions for choledocholithiasis, benign and malignant obstruction of the bile ducts, chronic pancreatitis accompanied by obstruction of the pancreatic ducts. Chapter 2 presents the results of the development of a thermoelectric device for diagnosing inflammatory processes and pain syndrome in degenerative-dystrophic diseases of the lumbosacral spine. Such a device makes it possible to save, process and visualize measurement results on the display of the device and on a personal computer in real time. The results of clinical studies of thermometric indicators in the lumbosacral region of the spine in persons with chronic pain syndrome against the background of degenerative-dystrophic pathology of the spine in the presence of hernias and protrusions of intervertebral discs are given. The effectiveness of the proposed thermoelectric device in medical practice has been confirmed. Chapter 3 presents the results of the examination of various contingents of the population: students, athletes, mobile operators, people with hearing loss, post-covid syndrome and psychophysiological lability developed under martial law. The features of information processing by examinees with different degrees of functional mobility of nervous processes are highlighted. It was found that the deprivation of auditory function, post-conviction syndrome, psychophysiological lability developed in the conditions of martial law significantly reduce the level of neural processes and the ability to process information. The evaluation scales of neurodynamic and sensorimotor functions proposed for use in the medical field can be used to optimize diagnosis and increase the effectiveness of monitoring neurological morbidity, including in people with special needs. Chapter 4 is devoted to the problems of children's neuropsychiatric diseases, in particular brain damage in children with ASD. Restrained optimism is expressed for the prospect of overcoming this severe psychiatric pathology in the foreseeable future due to the introduction of genetic, biochemical and immunodiagnostic approaches, as well as metabolic and immunotherapeutic interventions with neuroprotective effects. Arguments are presented in favor of the fact that the successful testing in clinical practice of evidence-based personalized multidisciplinary strategies of diagnosis and treatment will allow a breakthrough in the clinical management of children with severe mental disorders in the near future. This will provide not only the possibility of recovery from a prognostically unfavorable and currently incurable neuropsychiatric disorder, but will also contribute to stopping the large-scale threatening epidemic of neuropsychiatric syndromes in the modern child population. Chapter 5 presents the evolution of views on the problem of Internet addiction, provides information on its prevalence, comorbidity with mental disorders, and provides an overview of modern clinical classifications and psychometric tools for its diagnosis. A single definition of "cyber addiction" is singled out, based on the fact that the object of addiction is interaction with various information resources and technical means. The proposed clinical diagnostic criteria, which are based on the criteria for the diagnosis of mental and behavioral disorders due to the use of psychoactive substances ICD-11, and the characteristics of the boundary with normative behavior when using various information resources and technical means are provided. The development and validation of a new psychodiagnostic screening tool based on the proposed cyber addiction paradigm, the YSCAS scale, is presented. The monograph is intended for doctors and practitioners who are engaged in the search and implementation of effective diagnostic methods to overcome the problems associated with the detection and treatment of certain pathologies. The monograph can also be useful to postgraduate and master's students of universities in the relevant educational and scientific profile.
    Description: Published
    Keywords: Endoscopic retrograde cholangiopancreatography ; Endoscopic lithoextraction ; Osteochondrosis of the spine ; Thermoelectric device ; Individual-typological properties ; Functional mobility ; Sensorimotor reactivity ; Autism spectrum disorders ; Attention deficit hyperactivity disorder ; Obsessive-compulsive syndrome ; Immunodiagnostics ; Internet addiction ; Cyberaddiction ; YSCAS scale ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This reprint focuses on the importance of the micronutrient iron in human physiological iron homeostasis and iron-related diseases. Daily adequate dietary iron supply ensures vital body functions and hemoglobin synthesis during erythropoiesis. During the last few decades, scientific evidence has shown that the maintenance of human iron homeostasis is an important factor for physical and mental health. The present reprint gives an overview of how iron, as an essential dietary element, is responsible for physiological and pathological biochemical processes in the human body. For the readership, this relevant information will provide an evidence-based update on the complex regulatory mechanisms and related diseases of iron metabolism.
    Keywords: iron metabolism ; iron homeostasis ; micronutrient iron ; physiology ; pathology ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MF Pre-clinical medicine: basic sciences::MFG Physiology
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  • 45
    Publication Date: 2024-02-26
    Description: In the current scheme, the Institutions of Higher Education have the great responsibility to support academic growth and permanently guide the members of the university community in the teaching-learning process, in order to contribute to a better performance of the aspiring professionals who attend their classrooms. In recent times, respiratory system problems have been the cause of loss of life, especially since the appearance of COVID 19, which brought a pandemic of unprecedented proportions, which is why it is considered important to compile important data on this health issue. Considering that respiratory diseases are health problems that carry a high risk of impact on the quality of life of people and can cause death if they are not detected and treated in time, knowing about them and preventing them is a priority. In each area of specialty, we aim to comply with the established standards in an ethical and comprehensive manner. In the health area, the mission is to train a quality professional with an integral vision of the world, to form a man committed to the health problems that affect humanity, capable of facing critical situations of daily practice.
    Description: Published
    Description: En el esquema actual, las Instituciones de Educación Superior, tienen la gran responsabilidad de apoyar en el crecimiento académico y orientar de forma permanente en el proceso de enseñanza- aprendizaje, a los integrantes de la comunidad universitaria, con el fin de aportar para un mejor desempeño de los aspirantes a profesionales, que asisten a sus aulas. Los problemas del aparato respiratorio han sido en los últimos tiempos causa de pérdidas de vidas, en especial desde la aparición del COVID 19 que trajo una pandemia de proporciones nunca vistas, es por esa razón que se considera importante realizar una recopilación de datos importantes referentes a esta temática de salud. Considerando que las enfermedades respiratorias constituyen problemas de salud que conllevan un alto riesgo de impacto en la calidad de vida de las personas y que pueden causar la muerte de las personas sino se detectan se tratan a tiempo, conocerlas y prevenirlas es una prioridad. En cada área de especialidad, se pretende cumplir con los estándares establecidos en forma ética e integral. En el área de la salud la misión es formar un profesional de calidad, con una visión integral del mundo, formar un hombre comprometido con los problemas de salud, que afectan a la humanidad, capaz de enfrentar situaciones críticas de la práctica cotidiana.
    Keywords: Función Respiratoria ; Prevención ; Salud Pública ; Tratamiento ; bic Book Industry Communication::M Medicine
    Language: Spanish
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: This Special Issue addresses recent advances in the research of plant-derived natural products, their mechanisms of action and how they can influence health and disease. Plant-derived natural products have been well known since antiquity due to their beneficial effects on human health, and since then, they have attracted the interest of the scientific community, leading to the identification, isolation and quantification of their compounds and research on their biomedical properties. They have been found to be rich in phytochemicals, such as terpenes and phenolic compounds, with proven antioxidant, anti-inflammatory, antimicrobial, antitumor and prebiotic properties, and therefore, they have been suggested as potential candidates for the therapeutic management of several chronic diseases. Some of them include inflammatory bowel disease, diabetes, non-alcoholic fatty liver disease, arthritis and cancer, in which inflammation, oxidative stress and dysbiosis mechanisms are implicated. Furthermore, given the increased economic burden, the side effects and the low compliance rates of patients who receive standard medical treatments, plant-derived natural products could possibly serve as adjunct therapeutic agents for chronic diseases.
    Keywords: plants ; natural products ; free radicals ; inflammation ; medicinal ; caffeic acid ; antibacterial ; antifungal ; antioxidant ; anticancer ; juglone ; Juglans regia ; mogrol ; mogroside ; phytochemical ; pharmacology ; osteoporosis ; antiobesity ; anti-inflammation ; neurodegenerative disorders ; anticancer agents ; aromadendrane ; bryophytes ; cytokinesis inhibitor ; Plagiochila species ; plagiochilins ; analgesic activity ; traditional medicine ; wound healing ; colon carcinogenesis ; 1,2 dimethylhydrazine ; hesperetin ; capecitabine ; Jatropha tanjorensis ; Fraxinus micrantha ; HPTLC ; anti-obesity activity ; high-fat diet model ; histological ; Alzheimer ; acetylcholinesterase inhibitors ; Euonymus laxiflorus Champ. ; bioactive compounds ; medicinal plants ; P. lentiscus ; GC/MS ; HPLC-DAD ; antioxidant activity ; antibacterial activity ; antifungal activity ; extract ; molecular docking ; Artemisia arborescens ; Artemisia inculta ; phenolic compounds ; terpenes ; trace metals ; antioxidant capacity ; Eurycoma longifolia Jack ; anti-inflammatory ; antinociceptive effect ; antipyretic effects ; gastroprotective activity ; gastric ulcer ; Thai traditional medicine ; phytochemicals ; inflammatory bowel disease ; gut microbiota ; Mastiha ; Curcumin ; Boswellia serrata ; Artemisia absinthium ; lipidomic profile ; Tulsi ; Ocimum sanctum ; ischemic stroke ; photothrombotic ischemia ; medicinal plant ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Translational research is required to uncover the underlying pathomechanisms of neurological and psychiatric disorders, search for new biomarkers, and develop novel therapeutics. Complex polygenic, multifactorial, and heterogeneous mechanisms have been elucidated using in vivo and in vitro models. Advanced preclinical models have recently revealed an intriguing interaction between sex/gender and aging in the pathogenesis and clinical manifestations of neuropsychiatric disorders. Despite these advances, much work remains to be carried out to fully understand the underlying pathology of these conditions and to develop treatments that can significantly improve the lives of those who suffer from them. The current challenge in the field of neurological and psychiatric disorders is the development of disease-modifying, effective treatments for these complex and long-term debilitating conditions with a high malady burden. The first edition of this research topic, entitled 'Emerging Translational Research in Neurological and Psychiatric Diseases: From In Vitro to In Vivo Models,' emphasizes the importance of translational research in bridging the gap between basic research and clinical applications. Furthermore, it provided a venue for researchers to share their findings and progress in translational research in this field.
    Keywords: Alzheimer&rsquo ; s disease ; Parkinson&rsquo ; multiple sclerosis ; stroke ; migraine ; pain ; depressive disorder ; anxiety disorder ; autism spectrum disorder ; sleep wake disorders ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: undefined
    Keywords: Medicine ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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  • 49
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: Various classes of natural and synthetic molecules that can be classified as biomaterials find application in all fields of dentistry. Biomaterials should be biocompatible to minimise toxicity and bioactivity to ensure or simulate biological effects. They are used, for instance, to enhance antibacterial activity and improve the healing process. Calcium silicates, for illustration, are biomaterials used in endodontics that have proven their excellent biological, physico-chemical, and mechanical properties. However, some of these are considered too soluble, and this is almost completely due to their hardness when used as endodontic sealers, making endodontic retreatment very difficult. Despite manufacturers' best efforts, it is sometimes difficult to marry bioactivity, biocompatibility, and clinical benefits in a biomaterial; therefore, in this content, the work of researchers is invaluable.
    Keywords: calcium silicate cement ; retrograde materials ; premixed cement ; powder–liquid cement ; chemical composition ; EDX ; caries prevention ; anterior restorations ; ceramic ; dental veneers ; follow-up ; non-vital teeth ; porcelain laminate veneers ; vital teeth ; antimicrobial ; osseointegration ; surface modification ; tissue engineering ; root canal retreatment ; calcium silicate-based cement ; ProTaper Universal Retreatment ; D-Race ; dentin hypersensitivity ; desensitizing agents ; calcium phosphate ; hydroxyapatite ; nano-hydroxyapatite ; peri-implantitis ; periodontitis ; periapical radiograph ; deep learning ; neural networks ; image enhancement ; carious lesion activity ; irreversible pulpitis ; partial pulpotomy ; vital pulp therapy ; mineral trioxide aggregate ; furcation involvement ; image segmentation ; Gaussian high-pass filtering ; image preprocessing ; CNN ; calcium silicate material ; confocal laser scanning microscope ; deciduous tooth ; digital microscopy ; flowability ; micro-CT ; pulpectomy primary teeth ; root canal filling ; SEM ; zinc oxide eugenol ; bic Book Industry Communication::M Medicine
    Language: English
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    Appalachian State University | Appalachian State University
    Publication Date: 2024-04-02
    Description: Between the 1940s and 1970s, approxiately three million people left the Appalachian mountains in search of jobs in Midwest urban areas, such as Cincinnati, Chicago, and Detroit. Unfortunately, about a third of these people were forced into a life of long-term underclass dwellers. Struggling with questions of identity, rootlessness, and cultural negation, these people were given the name of “urban Appalachians.” Published in 1987, Too Few Tomorrows addresses some of the pressing questions regarding urban Appalachians and their story of migration to city life.
    Keywords: History ; United States ; State & Local ; South (al, Ar, Fl, Ga, Ky, La, Ms, Nc, Sc, Tn, Va, Wv) ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2024-01-08
    Description: The healthcare system’s ability to diagnose and care for people with schizophrenia has improved in recent decades, as effective pharmacological and psychosocial interventions are now available. However, schizophrenia remains a leading cause of disability and premature mortality. The utilization of pharmacological and psychosocial interventions in the healthcare system, which have the potential to significantly improve the quality of life for people with schizophrenia, heavily depends on medical professionals completing accurate and comprehensive assessments of patients’ psychopathologies, cognitive profiles, physical health statuses and any environmental factors that may influence them. This Special Issue reprint on schizophrenia, from the Journal of Clinical Medicine, presents a collection of articles on current approaches to assessment and treatment, as well as new findings and future perspectives of schizophrenia research and care.
    Keywords: schizophrenia ; ERP ; mismatch negativity ; MMN ; P3a ; illness duration ; real-life functioning ; motivation circuits ; negative symptoms ; RDoC ; positive valence system ; salience system ; deficit syndrome ; diagnosis ; cognitive function ; social skills training ; physical comorbidities ; childhood abuse ; internalized stigma ; neutrophil-to-lymphocyte ratio ; antipsychotics ; hypothyroidism ; inflammatory markers ; expressive deficits ; experiential deficits ; functioning ; quality of life ; first psychotic episode ; first episode ; emotional processing ; social cognition ; MCCB ; MSCEIT ; real-world studies ; real-world effectiveness ; tolerability ; treatment adherence ; second-generation antipsychotics ; long-acting injectable antipsychotics ; delusional disorders ; psychosis ; sex ; women ; psychopathology ; construct ; schizophrenia spectrum ; renaming ; rethinking ; revising ; effort expenditure ; recent-onset schizophrenia ; persistent negative symptoms ; motivation ; neuropeptide S ; cognitive functioning ; rehabilitation ; AEP ; QEEG ; switch ; extrapyramidal symptoms ; treatment ; cognitive deficits ; self-evaluation of negative symptoms ; health-related quality of life ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    New York University Press | NYU Press
    Publication Date: 2024-04-04
    Description: Choice Outstanding Academic Title 2003 A reinterpretation of early 20th century Deaf history, with sign language at its center During the nineteenth century, American schools for deaf education regarded sign language as the "natural language" of Deaf people, using it as the principal mode of instruction and communication. These schools inadvertently became the seedbeds of an emerging Deaf community and culture. But beginning in the 1880s, an oralist movement developed that sought to suppress sign language, removing Deaf teachers and requiring deaf people to learn speech and lip reading. Historians have all assumed that in the early decades of the twentieth century oralism triumphed overwhelmingly. Susan Burch shows us that everyone has it wrong; not only did Deaf students continue to use sign language in schools, hearing teachers relied on it as well. In Signs of Resistance, Susan Burch persuasively reinterprets early twentieth century Deaf history: using community sources such as Deaf newspapers, memoirs, films, and oral (sign language) interviews, Burch shows how the Deaf community mobilized to defend sign language and Deaf teachers, in the process facilitating the formation of collective Deaf consciousness, identity and political organization.
    Keywords: History of the Americas ; Disability: social aspects ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFM Disability: social aspects
    Language: English
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  • 53
    Publication Date: 2024-04-02
    Description: As part of an effort to assist Chile in developing a strategic program to foster the development of the health information technology (health IT) sector over the next five to ten years, this report assesses the current state of health IT adoption and implementation in Chile, as well as the challenges and opportunities facing the sector over the coming years.
    Keywords: Health Sciences ; History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBQ Medicolegal issues
    Language: English
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    University Press of Colorado | Utah State University Press
    Publication Date: 2024-04-02
    Description: The central issue Bush finds in these works is how their authors have dealt with the authority of Mormon Church leaders. As she puts it in her preface, "I use the phrase 'faithful transgression' to describe moments in the texts when each writer, explicitly or implicitly, commits herself in writing to trust her own ideas and authority over official religious authority while also conceiving of and depicting herself to be a 'faithful' member of the Church." Bush recognizes her book as her own act of faithful transgression. Writing it involved wrestling, she states, "with my own deeply ingrained religious beliefs and my equally compelling education in feminist theories that mean to liberate and empower women." Faithful Transgressions examines a remarkable group of authors and their highly readable and entertaining books. In producing the first significant book-length study of Mormon women's autobiographical writing, Bush rides a wave of memoir publishing and academic interest in autobiography and other life narratives. As she elucidates these works in relation to the religious tradition that played a major role in shaping them, she not only positions them in relation to feminist theory and current work on women's life writings but ties them to the long literary tradition of spiritual autobiography.
    Keywords: History ; Religion ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::Q Philosophy and Religion::QR Religion and beliefs::QRM Christianity::QRMB Christian Churches, denominations, groups
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  • 55
    Publication Date: 2024-04-04
    Description: This report shares an overview of the budget of the U.S. Department of Veterans Affairs (VA) and focuses particularly on health care spending and the Veterans Health Administration (VHA), including makeup of the veteran population, available health coverage, patterns of use, and potential areas of improvement.
    Keywords: History ; Health Sciences ; thema EDItEUR::N History and Archaeology::NH History::NHW Military history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::M Medicine and Nursing::MQ Nursing and ancillary services
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    CLACSO
    Publication Date: 2024-04-14
    Description: ste libro es expresión de las investigaciones realizadas por seis integrantes de la Línea Contextos, Prácticas Políticas y Políticas Públicas como parte del Programa Posdoctoral en Ciencias Sociales, Niñez y Juventud. Los trabajos que componen el segundo libro colectivo de esta línea fueron producidos entre el 2014 y el 2017 y abordan diferentes dimensiones de las vidas de niñas, niños y jóvenes de América Latina desde una perspectiva situada que, siendo rigurosa, asume el compromiso intelectual y político de aportar a la transformación de las condiciones en las que producen sus existencias. Si bien cada uno de los seis capítulos corresponde a investigaciones singulares llevadas a cabo por cada uno de los posdoctores en tres países de América Latina (Argentina, Brasil y Colombia), estos se alimentaron de los intercambios colectivos sostenidos en el espacio de trabajo que compartimos en la Línea del Posdoctorado. De esta manera, el libro puede leerse como el encuentro de seis textos con unidad y lógica en sí mismos, pero también como obra única en la que reverberan los diálogos sostenidos en el espacio común de trabajo que construimos en estos años. En este sentido, este texto es resultado de un proceso que demandó casi dos años de debates y reelaboraciones y que pasó por diversos momentos y circunstancias antes de que se hiciera posible su publicación. Agradecemos entonces la paciencia y la dedicación de las autoras —el azar o los procesos de igualdad de género quisieron que todas las autoras fueran mujeres— así como los comentarios y aportes de los otros colegas que integran la línea, cuyos trabajos ya han sido publicados o se editarán pronto. Asimismo, queremos agradecer al equipo de trabajo del posdoctorado que radica en el Centro de Estudios de Niñez y Juventudes (Cenju) del Cinde y la Universidad de Manizales (Sandra, Daniela, Julián), a los coordinadores de las otras líneas del programa (Toya, Patricia, Karina, Silvinha, José Manuel, Héctor Fabio, Fernanda, Myriam), a Sara Victoria Alvarado, a María Camila Ospina por aceptar con generosidad hacer el prólogo, a las instituciones coeditoras y, especialmente, a Lucía Rangel, quien compartió la coordinación de la línea junto a Pablo Vommaro hasta fines del 2016, momento en el que se incorporó Alejandra Barcala a este espacio. Este libro es también símbolo del trabajo que llevamos a cabo con Lucía y una bienvenida para Alejandra. La apuesta por publicar los capítulos en su idioma original (castellano o portugués) también es expresión de la vocación intercultural y latinoamericanista de esta obra. Los invitamos a compartir las páginas que siguen y a recorrer las experiencias de investigación y práctica intelectual que contienen. Esperamos que esta sea una manera de integrarse, al menos por algunos momentos, a la comunidad que constituimos en el Posdoctorado desde el 2010, que se potencia día a día con la publicación de obras como esta y con los ecos y debates que pueda generar. Buena lectura. "Pablo Vommaro y Alejandra Barcala"
    Keywords: Peace & Conflict Studies ; History ; Latin American Studies ; thema EDItEUR::Y Children’s, Teenage and Educational::YX Children’s / Teenage: Personal and social topics::YXZ Children’s / Teenage: Social issues / topics ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPV Political control and freedoms::JPVH Human rights, civil rights ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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    CLACSO
    Publication Date: 2024-04-08
    Description: Este libro permite, entre otras cosas, acercarse a la mayor parte de los desarrollos, las tendencias y los intereses teóricos que ocupan actualmente a los cientistas sociales en América Latina. Es un mapa capaz de mostrar mucho de lo que se está haciendo en el campo de la teoría social, y capaz también de mostrar mucho de lo que queda por hacer. Uno de los rasgos más notables de este mapa es su pluralidad. Se constata aquí que las más diversas tradiciones de pensamiento transitan por nuestro continente, y que son reelaboradas por nuevas lecturas de un modo tan vital como riguroso y consistente. Queda por saber si este pluralismo existente se irá todavía ampliando, si llegará a albergar más cabalmente tradiciones no tradicionales de pensamiento. Es decir, si podrá abrirse con más fuerza a un diálogo con puntos de vista sobre lo social, lo político y lo cultural provenientes de las epistemes no occidentales, o no completamente occidentales, que habitan el sur global.
    Keywords: Philosophy ; History ; Latin American Studies ; bic Book Industry Communication::H Humanities::HP Philosophy::HPS Social & political philosophy ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDT Topics in philosophy::QDTS Social and political philosophy ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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    CLACSO
    Publication Date: 2024-03-29
    Description: It is used to say that the first victim of a war is the truth. In fact, in a war in the strict sense or in a political war, the murder of the truth and the concealment of the facts occur profusely. It is not different in Brazil. Democracy was neither the first nor the only victim of the parliamentary coup (a.k.a. impeachment) in 2016. It was also the truth. Before the coup, and to justify it, anti-people and anti-national forces broadcasted, to exhaustion, a series of lies about the governments of the Workers Party (PT). The presentation of Dilma Rousseff
    Keywords: Political Science ; History ; Latin American Studies ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPH Political structure and processes::JPHV Political structures: democracy ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-01-05
    Description: Advancements in digital technologies are reshaping the world of dentistry, from prosthodontics to implant dentistry. Intraoral scanners, facial scanners, 3D printers, and milling machines have revolutionized the clinical approach and operative workflow in daily practice. However, digital dentistry brings several challenges to clinicians due to the rapid evolution of new technologies and the lack of evidence-based guidelines for their correct use. The aim of this Special Issue is to cover the latest advances in the development and application of digital technologies in prosthetic and implant dentistry. We wish to provide both clinicians and researchers with a comprehensive and up-to-date source of information on current trends, limitations, and potential future applications of digital technologies in daily clinical practice.
    Keywords: dental implants ; digital impression ; intraoral scanner ; CAD/CAM materials ; toothbrushing wear ; surface ; roughness ; surface integrity ; alveolar remodeling ; tooth extraction ; intraoral digital scanning ; imaging superimposition ; less traumatic surgery ; socket healing ; implantology ; computer-aided surgery ; image-guided surgery ; zygomatic implants ; navigation system ; dental implant ; bone level ; prospective study ; sub-crestal placement ; emergence profile ; guided surgery ; digital workflow ; stereolithographic surgical guide ; accuracy ; CAD–CAM ; DICOM–STL ; static guided surgery ; clinical study ; intraoral scanners ; digital dentistry ; impression techniques ; full-arch impression ; elderly population ; dimensional measurement accuracy ; implant scan ; operator ; precision ; scan area ; trueness ; occlusion ; overloading ; complications ; implant-supported restorations ; marginal bone loss ; oral implantology ; intraoral scan ; cone-beam computed tomography ; oral surgery ; emergence angle ; retrospective study ; bic Book Industry Communication::M Medicine
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: On 11 March 2020, the World Health Organization declared COVID-19 a global pandemic, and the disease now affects nearly every country and region. Nearly 18 months later, COVID-19, caused by SARS-CoV-2, continues to present significant challenges to health systems, public health, and the economy of countries across both hemispheres. The morbidity and mortality of the infection caused by SARS-CoV-2 has been significant, and various waves of disease outbreaks initially overwhelmed hospitals and clinics in many countries and continue to do so. This influences everyone, and public health countermeasures have been dramatic in terms of their impact on employment, social systems, and mental health. This Special Issue collection follows on from the Special Issue “COVID-19: Current Challenges and Future Perspectives” and provides an avenue for authors from various disciplines to provide feedback on the response to and our future global preparedness for COVID-19, as well as to disseminate critical information about SARS-CoV-2 and the associated COVID-19 pandemic.
    Keywords: COVID-19 ; new-onset DM ; severe infection ; mortality ; outbreak ; P.1 variant ; Gamma variant ; SARS-CoV-2 infection ; whole-genome sequencing ; pandemic ; overweight ; obesity ; Peru ; psychological impacts ; public health ; preparedness ; mRNA-1273 ; BNT162b2 ; TAK-919 ; SARS-CoV-2 ; post-vaccination ; healthcare personnel ; vaccination ; asymptomatic infection ; HIV ; infectious disease ; excess mortality ; regdanvimab ; remdesivir ; severe ; community transmission ; population density gradient ; Dhaka ; Bangladesh ; dengue ; undifferentiated febrile illness ; antigen testing ; variants ; reinfections ; breakthrough infections ; vaccine hesitancy ; sub-Saharan Africa ; pulmonary fibrosis ; postacute COVID-19 syndrome ; tuberculosis ; helminth coinfection ; coronavirus ; coordination ; health operations and technical expertise ; AFRO ; diarrhea ; liver ; pancreas ; inflammatory bowel diseases ; liver transplantation ; reproduction rate ; phylogenetic analysis ; clade GK ; D614G ; P681R ; cross-reactivity ; haemorrhage ; thrombocytopenia ; thrombosis ; severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) ; molecular diagnostics ; real-time polymerase chain reaction (RT-qPCR) ; economy ; income levels ; waves ; policy ; turning points ; occupational exposure ; risk factors ; personal protective equipment ; SIR model ; socio-behavioral aspects ; interaction distance ; school reopening strategy ; self-medication ; over-the-counter ; medicine use ; Pakistan ; clinical features ; Luanda ; Angola ; socioeconomic status ; risk perception ; risk prevention practices ; qualitative ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Epilepsy is one of the most prevalent neurological disorders and is characterized by recurrent seizures resulting from abnormal neuronal excitability in the central nervous system. Despite the availability of thirty-six antiseizure medications, about one-third of patients with epilepsy do not respond to the pharmacological treatment and develop a so-called “pharmaco-resistant epilepsy” or “refractory epilepsy.” Thus, there is an urgent need to develop novel, effective therapies based on novel mechanisms underlying neuronal excitability that leads to seizures. This reprint’s original research papers and review articles highlight unknown mechanisms underlying pharmaco-resistant resistant epilepsy, epileptogenesis, and seizure suppression.
    Keywords: 3CAI ; GRIA1 ; GRIA2 ; intractable epilepsy ; PICK1 ; protein kinase C ; pericytes ; mural cells ; cytokine ; blood-brain barrier ; neuroinflammation ; 3-phosphoinositide-dependent protein kinase-1 ; AKT ; cyclosporin A ; GluA1 ; GluR1 ; PDK1 ; refractory seizure ; temporal lobe epilepsy ; hippocampus ; 4-aminopyridine ; epilepsy model ; long-term potentiation ; AMPA receptor ; audiogenic epilepsy ; rodents ; fear reaction ; behavior genetics ; c-Fos ; early gene activation ; epileptogenesis ; lipopolysaccharide ; pentylenetetrazole ; post-traumatic epilepsy ; seizure susceptibility ; traumatic brain injury ; epilepsy ; ghrelin ; ghrelin receptor ; anxiety ; TRPV1 channels ; neuronal activity ; neuropsychiatric comorbidity ; immunofluorescence ; audiogenic kindling ; acoustically evoked seizures ; EACT ; generalized tonic-clonic seizures ; inherited epilepsy ; TMEM1A channels ; wild running seizures ; astrocyte ; ML365 ; pharmacoresistant epilepsy ; cortical atrophy ; hippocampal atrophy ; intracerebral electrode ; magnetic resonance imaging ; posttraumatic epilepsy ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
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    Duke University Press | Duke University Press Books
    Publication Date: 2024-04-02
    Description: The Surrendered is Peruvian public intellectual José Carlos Agüero's reflections on his parents—who were executed by the state for being Shining Path militants—as well as the legacies of the Peruvian internal armed conflict and the possibility for forgiveness and reconciliation in the face of hate.
    Keywords: History of the Americas; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JH Sociology and anthropology::JHB Sociology
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    University of Georgia Press
    Publication Date: 2024-04-02
    Description: Revolution and Regeneration is a book about the aging of the "young men of 1776," the men who came to adulthood with the American Revolution, found their identity merged with the new republic they had created, and grew old as the nation matured. As they identified themselves with their nation's past, so they used that past to judge their own lives and what they had accomplished, or failed to accomplish. Revolution and Regeneration is a marriage of psychohistory and intellectual history, applying the principles of the psychology of maturation to a generation whose experiences were crucial to our history-the generation of Adams, Jefferson, Hamilton, and Madison. Their need for identity drove them to demand independence for themselves and their communities. Revolution and Regeneration tells their stories, from youth to old age. The Georgia Open History Library has been made possible in part by a major grant from the National Endowment for the Humanities: Democracy demands wisdom. Any views, findings, conclusions, or recommendations expressed in this collection, do not necessarily represent those of the National Endowment for the Humanities.
    Keywords: History ; American Studies ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTV Revolutions, uprisings, rebellions
    Language: English
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    Publication Date: 2024-04-02
    Description: California’s Juvenile Justice Crime Prevention Act provides funds for counties to offer evidence-based programs for high-need juvenile probationers and at-risk youth. This report, based on the annual report to the state legislature, outlines the program’s success for six outcome measures (completion of probation, restitution, and community service; arrests; probation violations; and incarcerations) and county-required supplemental outcomes.
    Keywords: Law ; History ; Political Science ; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::L Law::LN Laws of specific jurisdictions and specific areas of law::LNF Criminal law: procedure and offences::LNFQ Juvenile criminal law ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKS Social welfare and social services::JKSW Emergency services::JKSW1 Police and security services ; thema EDItEUR::J Society and Social Sciences::JK Social services and welfare, criminology::JKV Crime and criminology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Currently, cancer is the second leading cause of death worldwide and is the most complex and challenging disease known to humankind. Due to the complex underlying mechanisms of tumorigenesis and tumor metastasis, as well as the intrinsic limitations of conventional cancer therapies, the effective treatment of cancer remains a great challenge. Novel therapeutic strategies with superior anticancer ability urgently need to be discovered. In recent years, nano-drug delivery systems have been extensively investigated and applied as alternatives to conventional cancer treatments. Cancer nanomedicines aim to achieve the targeted delivery of chemotherapeutic drugs to the tumor site, utilizing strategies such as passive targeting, active targeting and stimuli-triggered drug release, while simultaneously decreasing drug accumulation in normal tissues, which together lead to improved therapeutic efficacy and reduced side effects. Currently, several cancer nanomedicines are in regular use, and several others are in various stages of development.This Special Issue will highlight recent progress in the development of novel nanomedicines and targeted drug delivery systems for cancer therapy.
    Keywords: graphene quantum dot ; targeted drug delivery ; photothermal therapy ; chemo-therapy ; polymeric prodrug ; theranostic nanocomplex ; pH-triggering releasing ; magnetic targeting ; magnetic hyperthermia ; magnetic resonance imaging ; docetaxel ; adenosine receptors ; PLGA ; nanoparticles ; lung cancer ; Notch signaling ; RBPJ protein ; drug repurposing ; fidaxomicin ; acarbose ; schaftoside ; breast cancer ; experimental skin cancer ; entrapment efficacy ; ethosomes ; metformin ; in vitro permeation ; zeta potential ; sesamol ; albumin nanoparticles ; doxorubicin ; oxidative stress ; antioxidants ; tumor-derived membrane vesicles ; cancer therapy ; tumor vaccine ; personalized immunotherapy ; low-density lipoprotein ; nanoparticle ; tumor microenvironment-responsive ; magnetic nanofluid ; improved magnetic resonance imaging ; neutral-responsive Fenton reaction ; enhanced chemodynamic therapy ; brain targeting ; folate receptor ; glioma cancer ; erlotinib ; blood–brain barrier ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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    University of North Carolina Press
    Publication Date: 2024-04-02
    Description: A decade before the American Civil War, James Churchwill Vaughan (1828-1893) set out to fulfill his formerly enslaved father's dying wish that he should leave America to start a new life in Africa. Over the next forty years, Vaughan was taken captive, fought in African wars, built and rebuilt a livelihood, and led a revolt against white racism, finally becoming a successful merchant and the founder of a wealthy, educated, and politically active family. Tracing Vaughan's journey from South Carolina to Liberia to several parts of Yorubaland (present-day southwestern Nigeria), Lisa Lindsay documents this "free" man's struggle to find economic and political autonomy in an era when freedom was not clear and unhindered anywhere for people of African descent. In a tour de force of historical investigation on two continents, Lindsay tells a story of Vaughan's survival, prosperity, and activism against a seemingly endless series of obstacles. By following Vaughan's transatlantic journeys and comparing his experiences to those of his parents, contemporaries, and descendants in Nigeria and South Carolina, Lindsay reveals the expansive reach of slavery, the ambiguities of freedom, and the surprising ways that Africa, rather than America, offered new opportunities for people of African descent.
    Keywords: History ; American Studies ; African Studies ; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHH African history ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBF Social and ethical issues::JBFA Social discrimination and social justice
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    Publication Date: 2024-03-29
    Description: La presente antología contiene un amplio conjunto de textos que Fernando Martínez Heredia elaboró en función de los problemas sociales y retos que la práctica política socialista latinoamericana demandó al pensamiento con el objetivo de ir más allá de lo posible. Materiales vivos que nos incitan a pensar en tiempo de revolución para que, según dijera un humilde habanero que entregó su vida a esa empresa, los sueños de hoy se conviertan en la ley del mañana.
    Keywords: Political Science ; History ; Latin American Studies ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPF Political ideologies and movements::JPFC Far-left political ideologies and movements ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTQ Colonialism and imperialism
    Language: Spanish
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    Archaeopress Publishing Ltd
    Publication Date: 2024-04-02
    Description: Western Mesoamerican Calendars and Writing Systems draws together studies by some of the world’s leading experts presented at a conference held in December 2020, ‘The Origins and Developments of Central Mexican Calendars and Writing Systems’. Mesoamerica is one of the few places to witness the independent invention of writing. From the earliest attestations of this intellectual feat in the Late Preclassic period 900 bc-ad 150), writing spread throughout Mesoamerica, developing and diversifying into a series of distinct and independent scripts. With the exception of the celebrated phonetic decipherments of Maya and Aztec writing, which are now well-documented and can be fully read, most Mesoamerican writing systems remain little studied and undeciphered. This is particularly true of the writing systems of Western Mesoamerica, the topic of this volume.Bringing together new research on Western Mesoamerican writing systems, some contributions focus on specific features of a given writing system, whereas others offer state-of-the-art syntheses of whole writing systems. Two contributions focus on the calendar in particular, and associated notations, as integral parts of writing systems. Chapters are included on the writing system of Teotihuacan, the Ñuiñe writing of the Mixteca Baja and adjoining areas, the writing system of the Epiclassic period and Aztec writing of the Postclassic. These writing systems represent more than a millennium of written records and literacy in Mesoamerica, spanning from the Early Classic to the Late Postclassic (from the 2nd to the sixteenth centuries ad). Aztec writing even continued in use for several decades after the Spanish invasion of Mexico (ad 1519-1521), which saw the introduction of the Latin alphabet and the gradual obsolescence of Mesoamerican logophonetic writing systems.
    Keywords: History ; Latin America ; Pre-columbian Era ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
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    Institut français d’études andines
    Publication Date: 2024-04-02
    Description: El espejismo del mestizaje estudia la tensión irresuelta que genera el pensamiento que se ubica en la línea divisoria entre la modernidad, identificada con el desarrollo europeo, y la colonialidad, término con el que se revelan y denuncian los excesos y las limitaciones de la modernidad. Por ello, El espejismo del mestizaje afirma que no hay modernidad sin colonialidad, siendo esta última no sólo constitutiva de la primera, sino el lugar de enunciación que revela sus miserias y sus limitaciones. Este libro está sostenido por investigaciones que, al ser todavía poco conocidas por la academia angloparlante, constituyen, sin embargo, una novedosa perspectiva para repensar Latinoamérica. Aún más, El espejismo del mestizaje, que cuestiona la universalidad de las ciencias sociales y humanas, interviene decisivamente en la discursividad propia de las ciencias modernas, y, así configura otro espacio de producción de conocimientos que, de acuerdo con Walter Mignolo, es la construcción de un “paradigma otro”, una forma distinta de pensamiento que se atreve a ver el mundo “de otro modo”.
    Keywords: arte ; Bolivia ; cultura ; mestizaje ; política ; siglo XX ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: In this reprint, state-of-the-art research and review articles on emerging material systems for additive manufacturing (AM) are collected, with a focus on the process–structure–properties relationships. Additive manufacturing (AM) has grown and evolved rapidly in recent years. There are many exciting research and translational works in many areas of application, such as biomedical, aerospace and electronics. These advancements are typically coupled with materials development, which has resulted in more functionalities added to 3D-printed parts, such as multi-material fabrications and integration with machine learning or digital twins. Such enhancements in functionalities have enabled the evolution of AM from a rapid prototyping tool to an actual manufacturing solution. In this reprint, two reviews and thirteen original research articles are included to highlight the latest development in the field of materials science for AM.
    Keywords: titanium scaffolds ; 3D printing ; pore design ; selective laser melting ; lattice structures ; torsion ; design ; additive manufacturing ; functionally gradient lattice ; torsional stiffness ; energy absorption ; failure behavior ; ferritic steel ; heat treatment ; SLM ; nuclear application ; laser powder bed fusion ; solidification crack ; hot crack ; aluminum alloy powder ; EN AW-5083 ; AA5083 ; AlSi10Mg ; powder bed fusion ; metal matrix composites ; laser powder-bed fusion ; aluminum alloys ; reinforcement ; ceramic particulates ; grain refinement ; crystallographic texture ; mechanical properties ; laser-directed energy deposition ; melt pool ; process maps ; multi-fidelity Gaussian process ; Bayesian Optimization ; uncertainty quantification ; K418 alloy ; orientation ; phase ; microhardness ; color 3D printing ; penetration depth ; chromaticity ; image-based metric ; color reproduction ; Ti-24Nb-4Zr-8Sn ; titanium alloy ; biomedical engineering ; microstructure ; X-ray diffraction ; directed energy deposition ; shape-memory alloys ; joining of metals ; elemental powders ; 3D concrete printing (3DCP) ; hybrids ; geopolymer ; frost resistance ; UV radiation ; thermal conductivity ; surface finishing ; physical vapor deposition ; composites ; recycling ; polymer-matrix composites (PMCs) ; direct ink writing ; liquid deposition modeling ; glass fibers ; stainless steel ; AISI 316L ; AISI 630 (17-4PH) ; AISI 420 ; AISI 440C ; carbon content ; online monitoring ; electron beam melting ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Personalized medicine for Parkinson’s disease is a growing and emerging concept in light of recent recognition that Parkinson’s is a syndromic condition affecting multiple neurotransmitter systems, as well as brain and extracranial structures. The clinical expression is, thus, heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven “one size fits all” management strategies adopted in clinical practice are, therefore, often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this supplement of JPM, we present a selection of papers which address several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital “checklists” to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well. We are soliciting any papers addressing biomarkers, genetics and pharmacogenetics, treatment or complementary therapies for personalized or individualized treatment for PD.
    Keywords: Parkinson’s disease ; movement disorders ; periodontitis ; periodontal disease ; hematologic tests ; Vitamin D ; oral health ; Parkinson’s Disease ; cognition ; GABAergic signaling ; cerebellum ; MRS ; response inhibition ; non-motor symptoms ; carer stress ; older persons with Parkinson’s disease ; education ; lifestyle behaviours ; diet ; cross-sectional ; population study ; neurological disorders ; precision medicine ; genetics ; clinical trials ; Parkinson’s disease (PD) ; cognitive rehabilitation ; intervention ; deep brain stimulation ; levodopa-carbidopa intestinal gel ; apomorphine ; radiofrequency ; focused ultrasound ; induced pluripotent stem cells ; cell therapy ; gene therapy ; personalized medicine ; advanced Parkinson’s disease (APD) ; apomorphine subcutaneous infusion therapy ; pain ; intrajejunal ; levodopa ; motor and non-motor symptoms ; PKG (KinetiGrap) ; rehabilitation ; device-aided therapies ; personalised medicine ; Alzheimer’s disease ; clinical trial ; impulsive-compulsive disorders (ICD) ; dopaminergic therapy ; genetic markers ; pharmacogenetic ; polymorphisms ; insomnia ; sleep quality ; assessment ; young onset Parkinson’s (YOPD) ; Emiratis ; expatriate ; genetic ; epigenetics ; societal impact ; device aided therapies ; quality of life ; non motor symptoms ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: In the urological sphere, the number of tumor malignancies caused by cancer is continuously growing in Western countries. Although this is mainly due to the contemporary increase in the life expectancy of people in these geographic areas, many other factors are also contributing to this growth. Urological cancer is a complex and varied disease which affects different organs and mainly affects the male population. In fact, in most statistics, kidney, prostate, and bladder cancer are regularly included in the top-ten list of the most frequent neoplasms in males. The female population, however, has also been increasingly affected by renal and bladder cancer in the last decade. From these facts, it is clear that urological cancer is a problem of major concern in developed societies. This Topic Issue of Cancers intends to shed some light on the complexity of this field and will consider all useful and appropriate contributions from scientists and clinicians in order to improve urological cancer knowledge for patients’ benefit.
    Keywords: high-risk prostate cancer ; androgen receptor axis ; castration resistance ; neuroendocrine carcinoma ; PARP inhibition ; immunotherapy ; cancer genome ; precision targeting ; robot-assisted partial nephrectomy ; renal cell carcinoma ; indocyanine green ; nephron sparing ; prostate cancer survivors ; follow-up care ; primary health care ; general practice ; process evaluation ; Consolidated Framework for Implementation Research ; prostate-specific membrane antigen positron-emission tomography ; multiparametric magnetic-resonance imaging ; primary diagnosis ; prostate cancer ; systematic review ; diagnosis ; PSMA ; PSA ; tumor ; PET scan ; bladder cancer ; bisphenol A ; bisphenol S ; energy metabolism ; migration ; proliferation ; carbon-ion radiotherapy ; elderly patients ; radiotherapy ; particle beam therapy ; life expectancy ; systemic immune-inflammation index ; Charlson comorbidity index ; CAPRA-S ; early survival ; male incontinence ; robotic prostatectomy ; clear cell renal cell carcinoma ; ferroptosis ; prognostic model ; TCGA ; E-MTAB-1980 ; GLS2 ; pazopanib ; real-world data ; non-interventional study ; time on drug ; nivolumab ; everolimus ; trial-eligibility ; ureteral neoplasms ; urinary bladder neoplasms ; ureteroscopy ; CNTF ; CNTFRα ; LNCaP ; 22Rv1 ; castration resistant ; castration sensitive ; STAT3 ; ERK ; MMP ; biomarker ; Gleason grade ; transforming growth factor-β family ; activin ; INHBA ; INHBB ; INHBC ; prostate-specific antigen ; false-positive results ; real world-data ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJC Diseases & disorders::MJCL Oncology
    Language: English
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    RAND Corporation
    Publication Date: 2024-04-02
    Description: This book examines the strategic choices that American and Chinese decisionmakers face regarding sea power in the Western Pacific, shaped by geography, history, technology, and politics. In particular, the author explores the potential for cooperation on maritime security in the Western Pacific, and how the United States might pursue such cooperation as part of a broader strategy to advance its interests in the region.
    Keywords: History ; Political Science ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::J Society and Social Sciences::JW Warfare and defence::JWC Military forces and sectors::JWCK Naval forces and warfare ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JP Politics and government::JPS International relations
    Language: English
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  • 74
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    CLACSO
    Publication Date: 2024-04-02
    Description: Resultado de la orientación de investigación y exposición de académicas y académicos que valoraron como indispensable, para abordar los temas actuales de la frontera norte de México, el tener presente la complejidad y diversidad de su conformación histórica. Así, desde la diversidad de disciplinas Antropológicas y de la historia, las y los autores abordan temas que van de las primeras ocupaciones y aprovechamientos humanos del extenso territorio norteño de la actual república mexicana, hasta el estudio de los intereses estadounidenses en la geopolítica de lo que ellos han considerado su frontera sur, pasando por el largo periodo de invasión y conquista española de todo ese inmenso territorio y aun de los movimientos y estrategias de resistencia de los pueblos y comunidades indígenas, de ayer y hoy.
    Keywords: History ; Latin American Studies ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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  • 75
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-07-14
    Description: Global cancer incidence and death are expected to increase in the next decades. Inappropriate therapeutic regimens and tumor recurrence due to the development of drug resistance are two major clinical challenges impacting poor patient outcomes, which is critical to the discovery and development of new anticancer drugs. Over the last few decades, the marine environment has proved to be a key source of molecules with potent anticancer properties. The Special Issue, “Marine Natural Products as Anticancer Agents 2.0”, gathered eleven publications, including two reviews and nine research articles, about the anticancer activities of marine natural and/or derived products on in vitro 2D and 3D cellular models, and/or in vivo models of colorectal, breast, lung, myeloma, liver, leukemia, and melanoma cancers. Altogether, the eleven scientific papers published in this Special Issue provide an exciting overview of marine natural products as potential anticancer agents.
    Keywords: Clavatadine C ; spirocyclic bromotyrosines ; cytotoxicity ; cancer selectivity ; marine compounds ; melanoma A-375 cell line ; Sarcophyton convolutum ; sarcoconvolutum A–E ; cembrenoids ; anti-angiogenesis ; bromophenols ; tube formation ; vasculogenic mimicry ; brefeldin A ; ester derivative ; chronic myelogenous leukemia ; BCR-ABL ; proliferation inhibition ; molecular modeling ; 5-O-(N-Boc-l-alanine)-renieramycin T ; Xestospongia sp. ; marine sponge ; lung cancer ; anti-cancer ; cancer stem cells ; apoptosis ; Akt ; c-Myc ; migrastatics ; cell migration ; cell invasion ; metastasis ; terpenes ; algae ; marine natural products ; mitochondrial dysfunction ; oxidative stress ; anticancer ; Sphaerococcus coronopifolius ; seaweed ; Laminaria japonica ; Laminaria japonica peptides ; cancer ; liver ; cell cycle ; porphyrin ; Isabela ; hemin ; X-ray diffraction ; NOESY NMR ; cytotoxic ; colorectal cancer ; 5-fluorouracil ; 7S,15R-dihydroxy-16S,17S-epoxy-docosapentaenoic acid ; tumor-associated macrophages ; chemoresistance ; fucoidan ; immunopotentiation ; immunomodulatory ; immunotherapy ; cancer treatment ; cytokines ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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  • 76
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    Pennsylvania State University Press | University of Pennsylvania Press
    Publication Date: 2024-04-02
    Description: In 1803 in the colonial South American city of La Plata, Doña Martina Vilvado y Balverde presented herself to church and crown officials to denounce her husband of more than four years, Don Antonio Yta, as a "woman in disguise." Forced to submit to a medical inspection that revealed a woman's body, Don Antonio confessed to having been María Yta, but continued to assert his maleness and claimed to have a functional "member" that appeared, he said, when necessary. Passing to América is at once a historical biography and an in-depth examination of the sex/gender complex in an era before "gender" had been divorced from "sex." The book presents readers with the original court docket, including Don Antonio's extended confession, in which he tells his life story, and the equally extraordinary biographical sketch offered by Felipa Ybañez of her "son María," both in English translation and the original Spanish. Thomas A. Abercrombie's analysis not only grapples with how to understand the sex/gender system within the Spanish Atlantic empire at the turn of the nineteenth century but also explores what Antonio/María and contemporaries can teach us about the complexities of the relationship between sex and gender today. Passing to América brings to light a previously obscure case of gender transgression and puts Don Antonio's life into its social and historical context in order to explore the meaning of "trans" identity in Spain and its American colonies. This accessible and intriguing study provides new insight into historical and contemporary gender construction that will interest students and scholars of gender studies and colonial Spanish literature and history. This book is freely available in an open access edition thanks to TOME (Toward an Open Monograph Ecosystem)-a collaboration of the Association of American Universities, the Association of University Presses and the Association of Research Libraries-and the generous support of New York University. Learn more at the TOME website: openmonographs.org.
    Keywords: History ; Latin American Studies ; European Studies ; Feminist & Women's Studies ; Gender Studies ; Law ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::N History and Archaeology::NH History::NHD European history ; thema EDItEUR::N History and Archaeology::NH History::NHT History: specific events and topics::NHTB Social and cultural history ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSJ LGBTQ+ Studies / topics ; thema EDItEUR::L Law::LA Jurisprudence and general issues::LAZ Legal history
    Language: English
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  • 77
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    Temple University Press
    Publication Date: 2024-04-02
    Description: Throughout the late nineteenth century the hard coal industry was a major employer in Pennsylvania. The Commonwealth’s anthracite regions also played an important role in the economic development of the nation. Anthracite stimulated many pioneering developments in American railroading and provided important fuel to the iron industry. The hard-coal regions were among the first areas in Pennsylvania to yield to corporate domination. Yet their history, notably between the well-documented "Molly Maguires" and the coal strike of 1902, was largely unexplored. Although the area can be placed within the mainstream of American history, the anthracite regions developed a unique identity, the development of which can be found by studying the largest group in the area, the mine workers, and their problems between 1869 and 1897. Aurand documents and analyzes the problems facing mine workers, the resulting collective approach to addressing them, and the role of labor in the formation of a laboring class identity.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNX Industrial relations, occupational health and safety::KNXN Industrial arbitration and negotiation
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  • 78
    Publication Date: 2024-04-08
    Description: "Hemos organizado esta antología alrededor de cinco ejes temáticos que nos permiten establecer conversaciones cruzadas entre los ensayos incluidos y formular algunas tesis que claramente los enlazan y que asumimos como propias. Podríamos haber establecido muchas más relaciones entre ellos y articular otras tesis interpretativas, pero con ello escaparíamos los confines de un ensayo introductorio. Le dejamos a los amigos y amigas lectores el culminar una tarea que siempre permanecerá inconclusa. En todo caso, encontrarán a continuación una serie de relatos críticos a nuestra oficialidad y a los intereses que esta ha salvaguardado. Damos fe que la historia reciente, en buena medida, les ha dado la razón a estos pensadores. En Puerto Rico hemos gozado de una ventaja epistemológica que nos asigna un inusual grado de responsabilidad. Las causas de nuestra crisis no solo eran anticipables —mucho más previsibles que las azarosas rutas de los huracanes— sino que algunas nos fueron anunciadas desde hace medio siglo. Los que tuvimos el privilegio de ir a la universidad del estado —ahora, como todo, bajo asedio— pudimos leer y escuchar en sus aulas a algunos de estos autores, y a muchos otros que merecerían estar aquí. De todos aprendimos que a pesar de lo auspicioso que parecía el presente había encuadres narrativos plagados de ausencias, fallas sistémicas que atender, y nuevos rumbos que desde entonces no podían esperar. No todas esas ausencias que nos fueron señaladas están plasmadas en nuestra selección, ni todas las fallas sistémicas que debemos corregir son atendidas en esta colección. Esto nos pesa enormemente y esperamos que no desmerezca en un ápice la generosa clarividencia de los textos que les presentamos". De la Introducción de Anayra Santory Jorge y Mareia Quintero Rivera
    Keywords: Philosophy ; History ; Latin American Studies ; bic Book Industry Communication::H Humanities::HP Philosophy::HPC History of Western philosophy::HPCF Western philosophy, from c 1900 - ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy::QDH Philosophical traditions and schools of thought::QDHR Western philosophy from c 1800 ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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  • 79
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: This reprint emphasizes the perspectives and challenges surrounding COVID-19 and obesity-related cancers, including but not limited to the risk factors of severe COVID-19 in cancer patients; the complications of COVID-19 in cancer patients; the challenges in cancer treatment and surgery; guidelines for cancer care during COVID-19; delayed diagnosis and suboptimal cancer management; the impact of COVID-19 on cancer screening, early diagnosis and cancer presentation; immune response after SARS-CoV-2 infection and vaccination in cancer patients; psychological distress among cancer survivors; telehealth in cancer care; the role of diet and nutraceuticals in the prevention of severe COVID-19 and cancer; and the effects of COVID-19 pandemic on cancer research.
    Keywords: COVID-19 ; neutropenia ; G-CSF treatment ; respiratory failure ; colorectal neoplasms ; gastrointestinal neoplasms ; immune checkpoint inhibitors ; neoplasms ; oncogenic viruses ; oncolytic virotherapy ; post-acute COVID-19 syndrome ; reactive oxygen species ; tumor escape ; SARS-CoV-2 ; thyroid cancer ; differentiated thyroid cancer ; COVID-19 severity ; inflammation ; immunity ; oxidative stress ; obesity ; SARS-Cov-2 ; oncology ; cancer screening ; clinical trials ; melanoma ; management ; pandemic ; teledermatology ; diagnostic delay ; immunotherapy ; vaccination ; lymph adenopathy ; cancer ; nutraceuticals ; supplements ; colorectal ; meta-analysis ; gynecologic oncology ; malignancy ; blood cancer ; hematologic malignancy ; leukemia ; lymphoma ; multiple myeloma ; myelodysplasia ; breast cancer ; cancer care ; screening ; surgery ; psychological distress ; cancer therapies ; immunogenicity ; safety ; vaccine hesitancy ; tumor subtype ; mortality ; intensive care unit ; medico-administrative data ; France ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 80
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    CLACSO
    Publication Date: 2024-04-04
    Description: Los estudios sociales en ciencia y tecnología en América Latina cuentan ya con medio siglo de desarrollo en la región. El origen del campo en los años sesenta dotó de características propias que permanecieron, a lo largo de las décadas con diferentes niveles de intensidad, en el marco de nuevos modelos y formas de pensar el desarrollo y de afrontar las condiciones de pobreza y exclusión de nuestras sociedades. Una vez recorrida la etapa de profesionalización del campo –y en diálogo con la dinámica de construcción de estos estudios en los países del norte– se retomaron desde nuevas preguntas y perspectivas aquellas reflexiones iniciadas en los años sesenta, al tiempo que se generaron esfuerzos por construir miradas originales sobre los significados sociales, económicos y políticos de la ciencia y la tecnología. Así se construyeron enfoques y perspectivas analíticas que aprovechan los aportes del campo a nivel internacional y los alimentan con perspectivas regionales. Ciencia, tecnología y sociedad en América Latina está organizado en cinco secciones variadas y heterogéneas, referidas todas ellas a América Latina, en las que se discuten problemas sociales muy diversos. El rico caudal de estas investigaciones sostiene como objetivo común la superación del atraso y de la dependencia de nuestros países, y la búsqueda de estrategias adecuadas en pos de mejorar las condiciones de vida en la región. Con una perspectiva múltiple e interdisciplinar, investigadores jóvenes del continente muestran la riqueza y la relevancia de los estudios actuales en este campo.
    Keywords: General Science ; History ; Latin American Studies ; thema EDItEUR::P Mathematics and Science::PD Science: general issues ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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  • 81
    Publication Date: 2024-04-02
    Description: Gastroenterology and cardiology services are common and costly among Medicare beneficiaries. Episode-based payment models may offer a way to create incentives for high-quality, low-cost care. This report describes research related to the design of episode-based payment models for ambulatory gastroenterology and cardiology services for possible testing by the Centers for Medicare and Medicaid Services’ Center for Medicare and Medicaid Innovation.
    Keywords: Health Sciences ; History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues ; thema EDItEUR::M Medicine and Nursing::MB Medicine: general issues::MBP Health systems and services::MBPR Medical insurance
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  • 82
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This Book, entiled “Allergic Rhinosinusitis and Airway Diseases”, presents the concept of united airway disease interaction, which comprises chronic rhinosinusitis and other lower airway disorders such as asthma. This concept furthers a deeper comprehension on the pathophysiology and management of upper and lower airway diseases. In this Book, the published papers cover different interesting topics such as healthcare equality, advanced biomarkers, accurate diagnosis and treatment, occupational exposure-induced upper airway allergy and neoplastic disease mimicking chronic rhinosinusitis.
    Keywords: chronic rhinosinusitis ; B-cell lymphoproliferative disorder ; sinus ; nasal allergies ; tannery worker ; Kanpur ; asthma ; ovalbumin ; saffron ; salbutamol ; IL’s ; TNF-α ; allergic rhinitis ; bronchial asthma ; allergy ; Th17 cells ; IL-17 ; IL-33 ; microRNA ; miR ; airway mucosal inflammation ; united airway disease ; acute rhinosinusitis ; acute recurrent rhinosinusitis ; Mediterranean diet ; nutritional evaluation ; nutritional therapy ; olfactory dysfunction ; anosmia ; post-acute COVID-19 ; nitric oxide ; NO ; exhaled NO ; FENO ; nasal peak flow ; atopic status ; total IgE ; specific IgE ; childhood asthma ; immunoblot ; ImmunoCAP ; otolaryngology ; sinusitis ; ethnic groups ; patient-reported outcome measures ; quality of life ; social justice ; n/a ; bic Book Industry Communication::M Medicine
    Language: English
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  • 83
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    University Press of Colorado | Utah State University Press
    Publication Date: 2024-04-02
    Description: A project of the Utah Women’s History Association and cosponsored by the Utah State Historical Society, Paradigm or Paradox provides the first thorough survey of the complicated history of all Utah women. Some of the finest historians studying Utah examine the spectrum of significant social and cultural topics in the state’s history that particularly have involved or affected women.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 84
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on individualized treatment optimization. MIPD integrates mathematical models of drugs and diseases combined with individual patient characteristics (e.g., genotype, anthropometric factors, and organ function). MIPD has been highlighted as a useful tool for drug dosage selection in both the drug development process and clinical practice and it is a rapidly growing discipline that is supported by the main drug regulatory agencies. Despite the potential benefits of this methodology toward personalized medicine, its application is still limited. The Special Issue presented here includes several PKPD and PBPK models focused on improving the current state of art regarding the PK behaviour of different drugs with the aim of improving the efficacy/safety balance of these treatments and their clinical outcome; the Special Issue is intended to be of particular interest for clinical pharmacologists, pharmacometricians, and specific clinicians who routinely use the considered drugs.
    Keywords: model-informed precision dosing (MIPD) ; efficacy PKPD indexes ; pharmacokinetics ; pharmacodynamics ; PKPD modeling and simulation ; dosing algorithms ; nomograms ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::K Economics, finance, business & management::KN Industry & industrial studies::KND Manufacturing industries::KNDP Pharmaceutical industries
    Language: English
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  • 85
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-09-11
    Description: Ionizing radiation (IR) exposure can be deleterious for living tissues and eventually lead to illness or even death. DNA breakdown and the overproduction of highly reactive free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are considered initiators of IR-induced molecular and cellular damages, whereas NO, TGF-β and other pro-inflammatory cytokines are the primary effectors involved in radiation bystander effects (RIBE). Radiomodulators can reduce (radioprotectors and radiomitigators) or increase (radiosensitizers) IR damage. Past world events have highlighted the urgent need to develop predictive biomarkers of the IR absorbed dose and radiation countermeasures to reduce IR damage. Despite the strong economic and scientific efforts over the last decades, at present, drugs for effective protection against lethal IRs remain an unmet need. Moreover, the development of radiosensitizers that selectively increase IR damage in cancer cells but protecting, or at least do not affect, healthy tissues is also of unquestionable importance to improving patient survival and quality of life. It includes contributions that will help to understand the mechanisms involved in radiation-derived cellular responses and damage, the importance of free radical scavengers and antioxidant cellular defenses in preventing harm, and the relevance of the antiinflammatory response to improve recovery. In accordance, the mechanism of action and effectiveness of relevant radiomodulators are described and discussed, and novel clinical models and IR biomarker technologies are presented.
    Keywords: ferulic acid ; total body irradiation ; bone marrow microenvironment ; stem cell senescence ; bone marrow injury ; reactive oxygen species ; antioxidant defense system ; planarians ; model animal ; irradiation ; regeneration ; radioprotection ; radiation ; melatonin ; nDNA-repair ; mtDNA-mutations ; oxidation stress ; protection ; mitigation ; H2O2 ; ATP ; MDA ; GSH ; X-ray radiation ; 3T3 fibroblasts ; proliferation ; apoptosis ; cellular stress ; senescence ; peroxiredoxin 6 ; Prdx6 ; radioprotector ; pharmacologic ascorbate ; vitamin C ; pancreatic cancer ; Auranofin ; thioredoxin ; thioredoxin reductase ; peroxiredoxin ; nuclear and radiological emergencies ; radioprotectors ; radiomitigators ; radionuclide scavengers ; radiation biodosimetry ; Olea europaea L. cv. Caiazzana ; oleacein ; ionising radiation ; cancer ; radiotherapy ; normal tissue ; radiosensitization ; radiomodulation ; proteomic analysis ; oxidative modification profiling ; serum albumin ; amino acid sequences ; radiation biomarker ; human lactoferrin ; acute gamma irradiation ; C57Bl/6 mice ; survival rate ; open field test ; spleen ; serum homeostasis ; leukocytes ; stilbenoid ; electron paramagnetic resonance (EPR) ; FT-IR ; electron beam radiation ; radioresistance ; oxidative phosphorylation ; oncometabolites ; radiation response ; bioinformatics ; oxidative stress ; transcriptomics ; radiobiology database ; gene signature ; ionizing radiation ; intestine ; mucositis ; microbiome ; microbiota ; dysbiosis ; bacterial dietary supplement ; radiomitigator ; hyperthermia ; combination therapy ; synergistic effect ; oxygenation ; hypoxia ; immune response ; Tameron ; antioxidant ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
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  • 86
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    Temple University Press
    Publication Date: 2024-04-02
    Description: Mark Erlich wrote With Our Hands: The Story of Carpenters in Massachusetts, his history of the carpentry trade in Massachusetts, during an extraordinarily creative period in U.S. labor studies. The late 1970s saw the National Endowment for the Humanities and its state councils sponsoring ambitious public projects focused on labor unions, working-class culture, and community history. Two years after a diisplay commemorating the centenial of the United Brotherhood of Carpenters and Joiners of America appeared in the union's headquarters in Washington DC, Erlich, a journeyman carpenter in Boston’s Local 40, took up a new task: to research and narrate the lively hundred-year history of the carpenters union in Massachusetts, on the job, at the union hall, and in its busiest communities. Erlich built his work around everyday themes of work, family, and community. He documented and interpreted U.S. labor history along new lines, with less emphasis on institutions and more interest in working-class continuity via the union’s own stories. Erlich was determined that the reader would feel these histories as his or her own, achieved through his comprehensive narratives highlighted by vintage photos, historic documents, and excerpts from oral histories. The numerous photos allow glimpses of construction in the making, from building sites at their foundations, to a solitary worker climbing the laminated beams of an arched church roof, to a series of complicated interior angles of the “T" subway extension beneath the streets of Cambridge and Somerville.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KNX Industrial relations, occupational health and safety::KNXN Industrial arbitration and negotiation
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  • 87
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint contains articles published in the Special Issue entitled "Assessing Atmospheric Pollution and Its Impacts on the Human Health" in the journal Atmosphere. The research focuses on the evaluation of atmospheric pollution by statistical methods on the one hand, and on the other hand, on the evaluation of the relationship between the level of pollution and the extent of its effect on the population's health, especially on pulmonary diseases.
    Keywords: household air pollution ; fine particulate matter ; international environmental health ; cookstove ; respiratory disease ; brick worker ; particulate matter ; heavy metals ; Sulfate-Nitrate-Ammonium ; pollution levels ; mobile sources ; aerosols ; PAHs ; OC and EC ; transport sources ; urbanized coastal station ; grain dust ; health risk assessment ; Monte Carlo simulation ; disability adjusted life year ; multi-media exposure ; health risk ; probabilistic risk assessment ; Lake Chaohu ; PM10 ; health risks ; extreme learning machine ; echo state network ; neural networks ; pollution ; concentration ; indicators ; aberrant values ; nitrogen oxides ; ARIMA ; GRNN ; ARIMA–GRNN ; isolation forest ; LOF ; AOD ; classification ; dendrogram ; PCA ; air quality index ; polluting agents ; respiratory diseases ; monitoring stations ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology::MMGT Medical toxicology
    Language: English
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  • 88
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-05-11
    Description: There has been a rapid development in the academic literature over the last ten years on papers relating to individualization, personalization, patient-, client-, consumer- and person-centredness, with work on conceptual, instrumental, observational, and experimental levels. This Special Issue presents papers that can further establish the current state of science on these topics relating to personalized nursing and health care. We collected papers that highlight and further the knowledge base conceptually, instrumentally, observationally, and experimentally with sound theoretical and methodological underpinnings and implications for research, theory, and clinical work in the disciplines of nursing, medicine, allied health, and beyond.
    Keywords: anxiety ; life satisfaction ; life–work concerns ; melatonin ; cortisol ; biopsychosocial model ; obstetric complications ; patients’ rights ; student ; nursing ; personalized medicine ; HIV ; mobile health ; smartphone application ; symptom management ; nurse practitioners ; nursing home ; COVID-19 ; palliative care ; end-of-life ; dignified death ; older adults ; accidental falls ; fall prevention ; barriers ; patient compliance ; music therapy ; dementia ; caregiver ; RCT ; patient-centred care ; competence ; assessment ; instrument ; measurement ; validity ; reliability ; individual care ; nurses ; older diabetes patients ; physicians ; support ; Parkinson’s disease ; nursing training ; integrated care ; Parkinson nurse ; personalized care ; multidisciplinary care ; patient-centered ; arthritis ; autoimmune disease ; sociopsychological factors ; emotion ; depression ; self-identity ; qualitative study ; observational study ; dysmenorrhea ; kinesio tape ; auricular acupressure ; pain ; nursing care ; patient care planning ; quality of health care ; conditional inference trees ; education ; distance ; learning ; digital ; drawings ; Nigeria ; perinatal loss ; social networks ; stillbirth ; stillborn ; functional status ; health care ; hospitalization ; activities of daily living ; pelvic floor muscle exercises ; pelvic floor dysfunction ; qualitative research ; therapeutic exercise ; therapeutic adherence ; women’s health physiotherapy ; diabetes mellitus type 2 ; prediction model ; LogicRegression ; interpretability ; pelvic organ prolapse ; lifestyle changes ; women’s experience ; n/a ; foot ; foot self-care ; methodological review ; bic Book Industry Communication::M Medicine
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  • 89
    Publication Date: 2024-03-29
    Description: In the 2010–2011 school year, two educational programs launched in New Haven, Connecticut: New Haven School Change, a sweeping K–12 educational reform to improve the learning of educational outcomes of its students, and New Haven Promise, a scholarship program intended to improve college-going culture and encourage graduates to attend college. This report documents a study of early progress in these programs.
    Keywords: Education ; History ; bic Book Industry Communication::J Society & social sciences::JN Education::JNM Higher & further education, tertiary education ; bic Book Industry Communication::J Society & social sciences::JN Education::JNL Schools::JNLC Secondary schools ; bic Book Industry Communication::J Society & social sciences::JN Education::JNS Teaching of specific groups & persons with special educational needs::JNSV Teaching of students with English as a second language (TESOL) ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JN Education::JNM Higher education, tertiary education ; thema EDItEUR::J Society and Social Sciences::JN Education::JNL Schools and pre-schools::JNLC Secondary schools ; thema EDItEUR::J Society and Social Sciences::JN Education::JNU Teaching of a specific subject ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 90
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-03-07
    Description: Dry pasta is one of the most popular staple foods worldwide due to its convenience in terms of affordability, versatility, long shelf life, as well as sensory and nutritional value. As such, it represents a suitable carrier for health-promoting substances providing specific physiological functions. This Special Issue deals with the continuum aspects, “from seed to fork”, that could have an impact on the nutritional, sensory, and technological aspects of pasta. In this Special Issue, we aimed to publish innovative research and review papers on physico-chemical and sensorial characteristics, nutritional value, functional and technological properties of pasta, and pasta-making processes. New raw materials, new functional ingredients, up-cycling of waste materials, in vivo experiments to test the effect of assumption of the supplemented pasta, and innovative packaging systems will also be addressed in this Special Issue. Predictions of pasta quality adopting chemometrics as well as multi-variate and statistical data analysis approaches were welcomed. Finally, in the medium term, the international pasta market is expected to stay negative unless tangible product innovations are introduced, particularly regarding the technological innovations aimed at improving the products’ health benefits. This Special Issue aimed to provide a fundamental understanding and present the current strategies to improve the technological, nutritional, and sensory properties of pasta.
    Keywords: innovative pasta raw materials ; durum ; emmer ; spelt ; pasta ; brewers’ spent grain ; dietary fiber ; einkorn ; functional pasta ; tritordeum ; upcycling ; unconventional ingredients ; nutritional value ; cooking quality ; legumes ; Spirulina Platensis ; resistant starch ; hydrolysis index ; dietary fibre ; annealing ; slowly digestible starch ; carbohydrates ; fiber ; in vitro digestion ; micronization ; brown rice ; air fractionation ; parboiling ; rice pasta ; enriched pasta ; bioactive compound ; tuna ; sea bass ; Ω-3 fatty acids ; sensometrics ; TPA (texture profile analysis) ; glycemic index ; glycemic response ; durum wheat ; landraces ; starch ; available carbohydrates ; glycemic load ; texture profile analysis ; gluten-free ; celiac disease ; fish ; allergy ; pear, date, and apple by-products ; wheat flour ; sensorial properties ; scanning electron microscopy ; multiple factor analysis ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MB Medicine: general issues::MBP Health systems & services::MBPK Mental health services
    Language: English
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  • 91
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: This reprint contains several articles where the molecular mechanisms and structural changes in target proteins on interaction with various viruses and bacteria were studied. In addition, drug-protein interactions, drug–drug interaction mechanisms, anti-Glycating, antioxidant, binding affinity, network pharmacology-driven investigations, and targeted anticancer treatments were also investigated.
    Keywords: RSV ; ectodomain G protein ; heparan sulfate ; protein–ligand interaction ; fluorescence quenching ; molecular docking ; molecular dynamic simulation ; quercetin ; CCL4 ; neurotoxicity ; VirtualToxLab ; oxidative stress markers ; Huperzine A ; molecular dynamics simulation ; fluorescence spectroscopy ; human serum albumin ; neurodegenerative disorders ; drug–protein interactions ; erlotinib ; bovine serum albumin ; binding interaction ; competition ; hepatitis E virus ; methyltransferase ; protein stability ; enzyme assay ; garlic ; antioxidant ; anti-glycation ; glycation ; AGEs ; HSA ; quetiapine ; hydrophobic interaction ; thermodynamic parameters ; seproxetine ; antidepressant ; charge transfer ; π-acceptors ; DFT ; haloperidol ; antipsychotics ; keratoconus ; MMP-2 ; MMP-9 ; molecular dynamics ; MM-GBSA calculations ; pharmacophore mapping ; α-amylase ; advanced glycation end-products ; caffeic acid ; coumaric acid ; coronary artery disease ; phytotherapy ; network pharmacology ; angiogenesis ; zebrafish ; dynamics molecular docking ; NEK7 ; virtual screening ; DFTs ; deep learning ; drug design ; drug repurposing ; structural-based ; cancer ; A. aspera ; β-amyrin ; C. gigantea ; C. procera ; GC-MS ; Minimum inhibitory concentration (MIC) ; Molecular docking ; MD simulations ; Tuberculosis (TB) ; n/a ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MM Other branches of medicine::MMG Pharmacology
    Language: English
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  • 92
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    CLACSO
    Publication Date: 2024-04-02
    Description: A lo largo de doscientos años de autonomía en Centroamérica se ha demostrado suficientemente que las pretensiones de independencia, a pesar de consolidarse en el plano político, no abonaron para generar el cambio de las estructuras sociales y económicas. Abundantes análisis señalan la recurrente falta de visión y voluntad para reorientar el camino de los países centroamericanos. ¿En dónde está la región? ¿Qué perspectivas se pueden visualizar a partir de las condiciones con las que se convive cotidianamente? ¿Hay alternativas que subsanen los excesos del sistema vigente y que lo reorienten o transformen? Estos y otros más son los interrogantes que motivan y estimulan los quince ensayos que componen este libro colectivo, ganadores de la convocatoria organizada por la Secretaría Ejecutiva de CLACSO y los centros miembros de Centroamérica con la finalidad de poner en valor la relevancia del conocimiento producido por las y los investigadores.
    Keywords: History ; Latin American Studies ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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  • 93
    Publication Date: 2024-04-02
    Description: El estudio etnográfico sobre los chichimecas jonáz, reconoce en la historia a uno de los pueblos originarios cazadores-recolectores del centro-norte de México, más denostado desde la época prehispánica por los Mexica o Aztecas, considerados como “perros sucios, inciviles", significado del término chichimeca; bárbaros-salvajes, por los conquista- dores ibéricos; holgazanes, que no trabajan y no producen nada, por algunos habitantes de San Luis de la Paz, Guanajuato. El lector encontrará cómo los chichimecas-jonáz continúan siendo una sociedad marginal al resto de la sociedad dominante, pero resistiendo ante el embate del sistema capitalista que se apropia de sus territorios y fuerza laboral mediante megaproyectos extractivistas, energéticos, parques industriales y otros, que generan enormes ganancias a los capitales transnacionales, además de la expansión de las ciudades cercanas.
    Keywords: History ; Latin American Studies ; Sociology ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSL Ethnic studies::JBSL1 Ethnic groups and multicultural studies::JBSL11 Indigenous peoples ; thema EDItEUR::5 Interest qualifiers::5P Relating to specific groups and cultures or social and cultural interests::5PB Relating to peoples: ethnic groups, indigenous peoples, cultures and other groupings of people::5PBA Relating to Indigenous peoples
    Language: Spanish
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  • 94
    Publication Date: 2024-04-02
    Description: India’s core goals for Southeast Asia are in basic harmony with those of the United States, including regional stability, peaceful settlement of territorial disputes, and containment of radicalism Still, America should not expect India to enter any sort of alliance, nor join any coalition to balance against China, but should demonstrate strategic patience and willingness to cultivate a long-term relationship.
    Keywords: History ; thema EDItEUR::N History and Archaeology::NH History::NHF Asian history ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: English
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  • 95
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    University of North Carolina Press
    Publication Date: 2024-04-02
    Description: During the Great Depression, the American South was not merely "the nation's number one economic problem," as President Franklin Roosevelt declared. It was also a battlefield on which forces for and against social change were starting to form. For a white southern liberal like Jonathan Daniels, editor of the Raleigh News and Observer, it was a fascinating moment to explore. Attuned to culture as well as politics, Daniels knew the true South lay somewhere between Erskine Caldwell's Tobacco Road and Margaret Mitchell's Gone with the Wind. On May 5, 1937, he set out to find it, driving thousands of miles in his trusty Plymouth and ultimately interviewing even Mitchell herself. In Discovering the South historian Jennifer Ritterhouse pieces together Daniels's unpublished notes from his tour along with his published writings and a wealth of archival evidence to put this one man's journey through a South in transition into a larger context. Daniels's well chosen itinerary brought him face to face with the full range of political and cultural possibilities in the South of the 1930s, from New Deal liberalism and social planning in the Tennessee Valley Authority, to Communist agitation in the Scottsboro case, to planters' and industrialists' reactionary worldview and repressive violence. The result is a lively narrative of black and white southerners fighting for and against democratic social change at the start of the nation's long civil rights era. For more information on this book, see www.discoveringthesouth.org.
    Keywords: History ; American Studies ; African American Studies ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JB Society and culture: general::JBS Social groups, communities and identities::JBSL Ethnic studies
    Language: English
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  • 96
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-20
    Description: This book presents a collection of papers revealing the impact of advanced computation and instrumentation on healthcare. It highlights the increasing global trend driving innovation for a new era of multifunctional technologies for personalized digital healthcare. Moreover, it highlights that contemporary research on healthcare is performed on a multidisciplinary basis comprising computational engineering, biomedicine, biomedical engineering, electronic engineering, and automation engineering, among other areas.
    Keywords: eHealth ; mHealth ; telemedicine ; telehealth ; social sciences ; bibliometrics ; telediagnostic ; project management ; funding ; IT infrastructure ; cross-border multiprofessional team ; European Union ; Interreg ; reporting ; quality control ; resident ; diagnostic error ; artificial intelligence ; healthcare AI ; deployment and scaling ; medical center ; critical factors ; stakeholders ; health information technology ; information sharing ; hospital costs ; poverty ratio ; concentration ; continuous glucose monitoring ; insulin pump ; continuous subcutaneous insulin infusion ; pediatric diabetes ; biomedical data ; medical imaging ; shared data ; massive databases ; AI-based healthcare solutions ; trueness ; 3D printing ; milling ; interim dental crown ; digital dentistry ; dental device ; data mining ; bio-signal analysis ; bio-signal repository ; execution engine ; bio-signal monitoring ; digital healthcare ; patient-centric ; blockchain ; federated learning ; coronavirus (COVID-19) ; pandemic management ; healthcare transformation ; public health strategies ; stroke detection ; portable head scanner ; low-intensity EM waves ; intrinsically safe ; low carbon footprint ; orthodontic treatment ; clear aligners ; smart application ; AI ; computerized learning ; behavior change techniques ; decision tree algorithm ; digital interventions ; mental health literacy ; audiovisual ; dentistry ; computer-controlled local anesthetic delivery ; ultrasounds ; chemomechanical caries removal ; modern technologies ; laser ; ozone ; healthcare ; emergency department ; patient flow ; simulation modeling ; agent-based modeling ; pandemic decision support ; additive manufacturing ; patient-centric dosage form ; bic Book Industry Communication::M Medicine
    Language: English
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  • 97
    Publication Date: 2024-04-02
    Description: Reports the findings of an evaluation by a panel of experts on the extent to which a suicide prevention media campaign in California is aligned with best practices in the field.
    Keywords: Psychology ; History ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JM Psychology
    Language: English
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  • 98
    Publication Date: 2024-03-29
    Description: Los textos aquí publicados apoyaron las discusiones del seminario La defensa del territorio, la cultura y la vida de las comunidades campesinas e indígenas de América Latina y el Caribe ante el avance del capital extractivista, realizado del 12 al 16 de septiembre de 2019, en Asunción y que congregó a líderes de movimientos sociales campesinos e indígenas, organizaciones urbanas que luchan por el derecho a la tierra y a la ciudad, académicos de Argentina, Brasil, Colombia, México y Paraguay. La actividad pública se construyó en el marco de la XIX Reunión Anual del GT CLACSO Estudios Críticos del Desarrollo Rural, resultado de una alianza con la Facultad de Ciencias Sociales (FACSO) de la Universidad Nacional de Asunción (UNA), a través de su Dirección de Extensión Universitaria (DEU) y el Centro de Estudios Rurales Interdisciplinarios de Paraguay (CERI).
    Keywords: Political Science ; Latin American Studies ; History ; bic Book Industry Communication::J Society & social sciences::JP Politics & government ; bic Book Industry Communication::H Humanities::HB History::HBJ Regional & national history::HBJK History of the Americas ; thema EDItEUR::J Society and Social Sciences::JP Politics and government ; thema EDItEUR::N History and Archaeology::NH History::NHK History of the Americas
    Language: Spanish
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  • 99
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-04-05
    Description: As we know, strokes are one of the world's leading causes of death, and the cruel aspect of a stroke is that it leaves people with severe functional disability and/or cognitive impairment. Strokes have a significant impact on economies worldwide, as it is estimated that about 10% of the male population and 8% of the female population are affected by them. Such people need personal help in their everyday life and must be materially supported by social services. With the advancement of medicine, artificial intelligence, and new technologies have been developing rapidly and are gradually applied in diseases of the nervous system, increasingly helping diagnosis, treatment, rehabilitation, and prognosis of disease.This Special Issue has collected the 14 papers on artificial intelligence and new technologies in strokes, including in the aspects of diagnosis, treatment, prognosis, rehabilitation, and nursing. We welcome your reading.
    Keywords: non-invasive brain stimulation ; stroke ; spasticity ; meta-analysis ; hemiplegia ; electromyographic bridge ; upper limb rehabilitation ; randomized controlled trial ; hypoxic ischemic encephalopathy ; disorders of consciousness ; metabolic connectivity ; positron emission tomography ; 18F-fluorodeoxyglucose ; hand function rehabilitation ; hand rehabilitation robot ; computer vision technology ; wearable devices ; sensors ; artificial intelligence ; brain–computer interface ; active rehabilitation training ; motor function ; brain function ; executive function ; postural control ; gait ; repetitive transcranial stimulation ; facial paralysis ; peripheral magnetic stimulation ; blood flows ; laser speckle ; stroke rehabilitation ; upper limb ; automated system ; motor function assessment ; Fugl-Meyer Assessment ; motor attempt (MA) ; EEG ; deep learning method ; overlapping time window ; facial expression recognition (FER) ; vision transformer (ViT) ; convolutional neural networks (CNNs) ; rehabilitation ; assessment ; upper extremity ; hand ; brain–computer interfaces ; motor task ; sensorimotor rhythm ; hand rehabilitation ; motor imagery ; virtual reality ; rTMS ; DTI ; immersive virtual reality ; post-stroke cognitive impairment ; aging ; bic Book Industry Communication::M Medicine ; bic Book Industry Communication::M Medicine::MJ Clinical & internal medicine::MJN Neurology & clinical neurophysiology
    Language: English
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    MDPI - Multidisciplinary Digital Publishing Institute
    Publication Date: 2023-02-02
    Description: Hyperbaric oxygen is a known therapeutic agent, and treatments using this agent remain a matter of discussion and research. This Special Issue collection will add new knowledge and also offer some not so usual approaches to foster contemporary understanding and potential benefit for patients and scholars.
    Keywords: hyperbaric oxygen therapy (HBOT) ; Hyperoxia ; wound healing ; antimicrobial properties ; Coronavirus Disease-19 (COVID-19) ; critical flicker fusion frequency ; threshold of flicker fusion ; neuropsychology ; diving and hyperbaric medicine ; minimal hepatic encephalopathy ; diabetes ; hyperbaric oxygen therapy ; glycaemia ; oxygen ; hyperbaric oxygen ; epigenetics ; normobaric oxygen paradox ; hyperoxic-hypoxic paradox ; frostbite ; classification ; cold disease ; prognosis ; amputation ; medical outcome ; atmosphere exposure chambers ; diving physiology ; decompression ; periodontal disease ; oral health index ; dental mobility ; periodontal pockets depth ; subfoveal choroidal thickness ; intraocular pressure ; central corneal thickness ; central serous chorioretinopathy ; flow-mediated dilation ; arterial stiffness ; endothelial dysfunction ; n/a ; FMD ; underwater ; hyperbaric ; commercial diver ; off-shore energy operation ; human ; adverse effects ; autonomic nervous system ; lung ultrasound ; mixed gas diving ; pulmonary function ; technical diving ; bic Book Industry Communication::M Medicine
    Language: English
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