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  • thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases  (58)
  • Biology, life sciences  (30)
  • IntechOpen  (88)
  • English  (88)
  • French
  • Japanese
  • 2020-2024  (88)
  • 1980-1984
  • 2023  (88)
  • 1982
Collection
Keywords
Language
  • English  (88)
  • French
  • Japanese
Years
  • 2020-2024  (88)
  • 1980-1984
Year
  • 1
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Staphylococcus aureus is a coccus, gram-positive, non-spore forming, and non-motile bacterium. Its commensal and opportunistic capabilities make it able to colonize different sites of animals and humans. Resistance to antibiotics has resulted in development of new strains and new types within strains. Types of methicillin-resistant S. aureus (MRSA) include hospital-acquired MRSA (HA-MRSA), community-acquired MRSA (CA-MRSA), and livestock-acquired MRSA (LA-MRSA). There are also new strains like vancomycin-resistant S. aureus (VRSA) and vancomycin-intermediate S. aureus (VISA). Expansion in resistance is expected to give rise to newer strains resistant to antibiotics such as macrolide (erm gene), tetracycline (tet genes), mupirocin (mupR), and fusidic acid (fusD). Alternative approaches like nanoparticles, bacteriophages, phytochemicals, and more are required to tackle this pathogen. This book contains information on epidemiology, resistance mechanisms, and alternative ways to curtail S. aureus infection, as well as future research opportunities.
    Keywords: mrsa, s. aureus, environment, cytokines, bacteria, pathogenesis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 2
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Bacterial biofilms are colonies of bacterial cells embedded in their self-produced matrix composed of polysaccharides, DNA, and proteins. They protect bacterial cells against antibiotics, antibacterial agents, soaps and detergents, and shear stress. Some of the most common biofilm-associated infections in humans include urinary tract infections, infection of wounds and surgical sites, diabetic foot ulcers, dental caries (tooth decay) and gingivitis (gum inflammation), ventilator-associated infections, sinusitis, microbial keratitis, secondary infection related to Covid-19 and other viral infections, and so on. Bacterial resistance to common antibiotics (e.g., penicillin, gentamycin, erythromycin, ciprofloxacin, etc.) is driving us to a catastrophic failure of our health systems. Strategies to develop novel antibacterial agents and technology must be prioritized to combat and eradicate biofilms and their associated challenges. This book provides a comprehensive overview of biofilms with chapters on bacterial virulence factors, quorum sensing in bacteria, antimicrobial resistance in bacteria, strategies to develop new antibacterial agents, and much more.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 3
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The true incidence of histoplasmosis remains difficult to ascertain due to the lack of mandatory notification of the disease, resulting in an underestimation of its actual burden. Given the high mortality rate, especially for disseminated forms in immunocompromised patients, we must remain vigilant against fungal disease. This book, born out of a deep desire to expand our knowledge of this fungal disease and update the latest findings, is intended to assist clinicians in recognizing and effectively managing histoplasmosis, especially those who live outside endemic areas and are less familiar with this pathology. With the latest insights into epidemiology, pathophysiology, clinical manifestations, and diagnostic approaches for both immunocompetent and immunodeficient patients, this comprehensive volume provides infectious disease specialists, pulmonologists, and laboratory physicians with the tools they need to optimize the management of histoplasmosis.
    Keywords: histoplasma capsulatum, drug delivery, hiv, nanotechnology, liposomes, immunosuppression ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 4
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book aims to provide readers with some of the current trends in mycology. Its chapters include discussions on the major invasive fungal diseases, host-pathogen interactions, relationships between fungal growth and the environment, the use of fungal species to control soil parasites, and the antifungal properties of thiosulfonates. The information herein covers topics in mycological research and will be of interest to students and researchers in all biological sciences.
    Keywords: surgery, pathogenesis, water, fungi, microbiota, soil ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 5
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Chlorophyll, a green pigment present in almost all plants, algae, and cyanobacteria, is a significant biomolecule essential to photosynthesis, the process by which plants convert light into energy. This book provides a comprehensive and easy-to-understand source of information on the latest developments in chlorophyll research. It is a collection of contributions from leading specialists in the subject. Topics discussed include the medicinal uses of chlorophyll, the electronic structure of chlorophyll monomers and oligomers, and chlorophyll estimate from fluorescence vertical profiles in the ocean.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 6
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: As in many areas of medicine, treatment of viral hepatitis has seen an acceleration of change driven by new therapies and evolving technology. Thanks to the direct-acting antiviral agents (DAAs), the era of HCV eradication and cure has begun. As regards to hepatitis B therapy, potent antiviral drugs for suppression of viral replication are available, new research activities to enhance eradication are visible, and these may influence clinical practice in the coming years. This book covers the latest advances in hepatitis C and hepatitis B therapeutics as well as the emerging and investigational treatment strategies. "Advances in Treatment of Hepatitis C and Hepatitis B" book is an up-to-date source of information for physicians, residents, and advanced medical students seeking a broader understanding of treatment of viral hepatitis. The authors of the chapters come from many eminent centers around the world and are experts in their respective fields.
    Keywords: hepatocellular carcinoma, hepatitis c virus, hepatitis b virus, direct-acting antivirals, hepatitis b, antivirals ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 7
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book provides updated information to scientists and clinicians on taeniosis/cysticercosis, a parasitic infection caused by eating undercooked beef or pork that is a serious health and veterinary problem in many developing countries. It discusses incidence, risk factors, diagnosis, immunology, symptoms, rare manifestations, and advances in treatment including vaccination and novel drug therapies.
    Keywords: biomarkers, mirnas, immunosuppression, parasites, inhibitor, genome ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 8
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Revisiting Plant Biostimulants focuses on recent advances in plant biostimulants (PBs), an eco-friendly sustainable technology that supports the increased agricultural production required to feed rapidly growing populations. PBs contain diverse bioactive natural substances: (i) humic and fulvic acids, (ii) animal and vegetal protein hydrolysates, (iii) macroalgae seaweed extracts, and (iv) silicon, as well as beneficial microorganisms. There are many concerns about the sustainability of current conventional methods as continued use of chemicals degrades both soil and the environment. This book explores the use of PBs, and their potential responses to current and impending environmental change.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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  • 9
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Insects are a group of animals that contribute significantly to the proper functioning of different ecosystems on the planet. They provide services such as pollinating crops, recycling nutrients and controlling pests. Many scientific publications and reports have studied the current global decline of insects. This decline can severely affect other groups of animals including birds, reptiles, amphibians, fish, and small mammals that utilize insects as a source of food. This will have a great impact on the trophic cascade and an eventual adverse effect on the overall ecosystem. This book provides insights into the possible reasons behind the decline of insects as well as potential measures that might mitigate this decline. It contains eleven chapters written by different experts. The book is useful for a wide range of readers including entomologists, ecologists, botanists, environmentalists, and amateurs who love collecting and preserving insects.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences::PSVA Zoology: invertebrates::PSVA2 Insects (entomology)
    Language: English
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  • 10
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Modern medicine is impossible without antibiotics, but global antibiotic usage has led to the development of increasing numbers of multi-drug resistant (MDR) bacteria. Thus, we still have problems with infectious disease treatment despite an arsenal of antibiotics. This has forced researchers to develop new drugs that will be effective against resistant bacteria. Some of these prospective molecules are antimicrobial peptides (AMPs), which are an important component of the innate immune system of various organisms in nature. Currently, more than 3,000 AMPs have been reported with different activities against different bacterial species including resistant phenotype bacteria. AMPs display remarkable structural and functional diversity that is not completely understood. As such, this book presents a comprehensive overview of AMPs and their mechanism of action against MDR bacteria.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 11
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Malaria remains a leading cause of morbidity and mortality worldwide. Children in Africa and selected regions of Asia and Southern America are especially widely affected. Written by expert research teams, this book describes different aspects of the epidemiology, pathobiology, diagnosis, prevention, and treatment of malaria. Chapters highlight current research as well as the gold standards for diagnosis and treatment of the disease, examining recent advances, remaining pitfalls, and novel ideas about prophylaxis and therapy.
    Keywords: plasmodium falciparum ; oxidative stress ; pathogenesis ; mortality ; antioxidant activity ; pcr ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 12
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Grasslands are of vital significance globally by covering more than one-quarter of the earth’s surface. They are known by a variety of names, such as prairies, pampas, steppes, savannas, and so on, and provide feed to animals as well as serve as biodiversity reserves and catchment areas. Under the changing climate scenario, they can potentially serve as carbon sinks, which might alleviate the adverse effects of greenhouse gas emissions. This book provides fundamental knowledge of underutilized grasses of economic significance as well as discusses advancements in grasslands management for boosting their bio-productivity. There is a particular focus on state-of-the-art strategies for the restoration and conservation of grasslands in the era of changing climate.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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  • 13
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book offers a broad perspective on marine mammal species and populations considered to be most at risk due to human activities. It emphasizes the importance of understanding the essential biology and ecology of marine mammals to assess the correlates and causes of extinction and to implement science-based conservation. Chapters address such topics as different types of marine mammals and their importance to the ecosystem of the world’s oceans and food cycles, lactation in marine mammals, dolphin survival rates and causes of movement reduction in Bangladesh, and much more.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSP Hydrobiology::PSPM Marine biology
    Language: English
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  • 14
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The study of staphylococci has a long way to go, due to the great significance both for humans and for dairy or companion animals of their large number of virulence factors. Their resistance to antibiotics makes these microorganisms become highly pathogenic species that can cause infections ranging from mild to fatal. Staphylococci, especially S. aureus and strains resistant to methicillin (MRSA), are among the most studied microorganisms worldwide. This book covers recent advances in the study of staphylococci. The book is divided into four sections that cover four important events for the study and combat of staphylococci: colonization, epidemiology and pathogenesis, diagnosis, and new treatments. Staphylococci can present a broad spectrum of resistance to antibiotics, which is why their elimination has become difficult. The final section of the book is devoted to new compounds for the fight against staphylococci. We hope that the information contained in this book will be useful for the study and investigation of these medically important microorganisms.
    Keywords: biofilm ; antibiotic resistance ; staphylococcus aureus ; mrsa ; nanoparticles ; medicinal plants ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 15
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: More than 2,500 serotypes of Salmonella exist. However, only some of these serotypes have been frequently associated with food-borne illnesses. Salmonella is the second most dominant bacterial cause of food-borne gastroenteritis worldwide. Often, most people who suffer from Salmonella infections have temporary gastroenteritis, which usually does not require treatment. However, when infection becomes invasive, antimicrobial treatment is mandatory. Symptoms generally occur 8 to 72 hours after ingestion of the pathogen and can last 3 to 5 days. Children, the elderly, and immunocompromised individuals are the most susceptible to salmonellosis infections. The annual economic cost due to food-borne Salmonella infections in the United States alone is estimated at $2.4 billion, with an estimated 1.4 million cases of salmonellosis and more than 500 deaths annually. This book contains nineteen chapters which cover a range of different topics, such as the role of foods in Salmonella infections, food-borne outbreaks caused by Salmonella, biofilm formation, antimicrobial drug resistance of Salmonella isolates, methods for controlling Salmonella in food, and Salmonella isolation and identification methods.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 16
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: It is vital to understand ticks and tick-borne pathogens as well as their impact on humans. This book is intended for students in parasitology, biologists, parasitologists involved in molecular diagnostics of tick-borne diseases, practicing veterinarians, and for others who may require information on ticks and tick-borne diseases. Here we have put together a collection of chapters focused on different aspects of ticks and tick-borne diseases mainly to provide the reader with novel information in the field, but not the basic generalised information provided by many textbooks. This book includes topics such as high-throughput technologies in diagnosis, discovery of novel tick vaccines, identification of new pathogens transmitted by ticks, and new epidemiological information of certain well-known ticks and tick-borne diseases. These chapters were authored by parasitologists from all over the world, giving an insight to the reader about significant ticks and tick-borne diseases prevalent in those particular geographical regions with the local expert's point of view. Each of the chapters has separate reference lists, making it easier for the reader to find additional reading material related to their topic of interest.
    Keywords: cattle, epidemiology, microbiota, bioinformatics, poultry, transmission ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 17
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: The HIV epidemic has had a significant and profound impact on the world and health resources. Considerable progress has been made in understanding the risks and drivers of the epidemic. Antiretroviral drugs have relieved human suffering and prolonged life. However, access to quality management needs to scale up and be made universal. This book discusses critical issues related to the treatment of HIV infection and related co-infections and challenges in adherence and discordancy. New vaccine approaches discussed may provide the ultimate solution for eradication. Sharing knowledge from various experts in medical and basic sciences improves the quality of care for this persistent global threat. This book discusses emerging advances in HIV-AIDS management to support strategies for control and elimination.
    Keywords: inflammation, heart failure, mitochondria, aging, cardiovascular disease, innate immunity ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 18
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Infection is a common clinical condition that may cause local inflammation but, in some cases, can lead to systemic inflammation, with sepsis and organ dysfunction. Septic shock is a condition of inadequate tissue perfusion and cellular use of oxygen due to the cytotoxic action of bacterial toxins. There is no relationship between the pathological characteristics and the severity of the primary septic outbreak and the development of septic shock, and the time that elapses until the start of the shock is not predictable. Thus, knowledge of the pathophysiology of septic shock is fundamental for treatment. This book presents a comprehensive overview of infectious agents and their therapeutic control, pathological conditions with infective etiology such as diabetic foot osteomyelitis and infections in neurosurgery, and the pathophysiology, diagnosis, and management of sepsis.
    Keywords: inflammation, critical care, septic shock, oxidative stress, machine learning, immunotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 19
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: The autonomic nervous system (ANS) is a subsystem of the nervous system that possesses several levels (groups) for receiving, transmitting, generating, and processing information. This book presents a comprehensive overview of the ANS, including chapters on the role of the ANS in a healthy lifestyle, the ANS–stress relationship, general anesthesia and the ANS, signaling pathways, and more.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 20
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Almost a decade has passed since the last textbook on the science of cryobiology, Life in the Frozen State, was published. Recently, there have been some serious tectonic shifts in cryobiology which were perhaps not seen on the surface but will have a profound effect on both the future of cryobiology and the development of new cryopreservation methods. We feel that it is time to revise the previous paradigms and dogmas, discuss the conceptually new cryobiological ideas, and introduce the recently emerged practical protocols for cryopreservation. The present books, "Current Frontiers in Cryobiology" and "Current Frontiers in Cryopreservation" will serve the purpose. This is a global effort by scientists from 27 countries from all continents and we hope it will be interesting to a wide audience.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 21
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: This book provides an overview of norovirus, a viral infection that adversely affects the gastrointestinal system. Unfortunately, there is no specific treatment available for this illness. As such, the World Health Organization (WHO) has identified norovirus as a priority disease for vaccine development. Chapters in this edited volume cover such topics as examination methods and genome mechanisms of norovirus, and clinical and pharmaceutical developments in managing this illness.
    Keywords: optimization, vaccine, genetic diversity, immunity, elisa, standardization ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 22
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Meningoencephalitis remains a major global threat, despite the prevention, diagnosis, and antibiotic therapy that have been improved considerably in the last years. In this thematic issue, the scientists present their results of accomplished studies, in order to provide several guidelines regarding the strategies of diagnosis and treatment of patients with meningoencephalitis, by adding valuable data and thus helping public health decision.
    Keywords: meningitis, epidemiology, pathogenesis, vaccination, clinical manifestations ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 23
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Malaria is still the main vector-borne parasitic disease in the world. Fortunately, elimination of this disease was achieved in multiple countries during the last decades. During the last decade, a significant reduction of malaria in the Americas was achieved. Nevertheless, many challenges still are ahead in order to reach a higher control and to continue in the elimination toward a world free of malaria in the next decades. This book tries to update the significant epidemiological and clinical research in many aspects with a multinational perspective. This book with 20 chapters is organized into 5 major sections: (I) Clinical and Epidemiological Aspects, (II) Basic Science, (III) Therapeutics and Antimalarials, (IV) Vaccines, and (V) Entomology and Vector Control.
    Keywords: vaccine, immune response, plasmodium falciparum, inflammation, environment, pregnancy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 24
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Human helminthiasis, known as worm infections, is any macroparasitic disease affecting humans, in which a part of the body is invaded by a lot of worms, known as helminths. They are broadly classified into flukes, tapeworms, and roundworms. Soil-transmitted helminthiasis and schistosomiasis are the most important, being included into the neglected tropical diseases. Helminthiasis has been found to result in poor birth outcome, less cognitive development, lower school and work performance, lower socioeconomic development, and poverty. Soil-transmitted helminthiases are responsible for parasitic infections in as much as a quarter of the human population worldwide. This group of infective diseases has been targeted under the joint action of the world's leading pharmaceutical companies and local governments, trying to achieve their eradication.
    Keywords: helminths, epidemiology, infection, chemotherapy, mass spectrometry, wastewater ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 25
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Characterized as a common signaling pathway between cells, the purinergic system is capable of modulating physiological and biochemical processes. Composed of signaling molecules, regulatory enzymes, and specific receptors, this organization can modulate several basal pathways of the organism. It is understood that purinergic signaling is present in all aspects of immunity and inflammation and studies show that extracellular ATP and its adenosine metabolite are the main mediators of response. These occur since most immune cells express P2 and P1 receptors, which are sensitive to the ATP and adenosine molecules, respectively. This book describes the purinergic system and its correlation with the health and disease process.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
    Language: English
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  • 26
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Dengue Fever in a One Health Perspective - Latest Research and Recent Advances presents studies on dengue fever (DF) and dengue virus (DENV) that discuss eco-epidemiology, physiopathology, and new biotechnological tools to fight against this important disease in the context of the World Health Organization’s One Health strategy. The book is organized into five sections: “Epidemiological Aspects”, “Environmental Aspects”, “Pathogenicity”, “Diagnosis and Treatment” and “Management Strategies”. The chapters address topics such as DF prevalence and management in a Chinese county, the risk of DF in American children younger than 15 years, the silent transmission of DENV by asymptomatic individuals, the use of X-ray and ultrasound to identify severe DF cases, gene-silencing techniques to investigate biological aspects of DF, viral genomic surveillance to promote early intervention in DF epidemics, and much more.
    Keywords: dengue virus ; epidemiology ; epilepsy ; genetic engineering ; community ; crispr ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 27
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Chlamydia infections continue to pose a serious socioeconomic burden globally. Despite advances in diagnostic tests in recent decades, chlamydial infections still cannot be controlled, neither in developed countries nor in developing countries. Chlamydial infections date back to the beginning of recorded human history. Trachoma caused by Chlamydia trachomatis, which progresses to blindness, is mentioned in ancient Chinese inscriptions and Egyptian scrolls. Today, we must better apply our knowledge against this clever and evolving obligate intracellular parasitic microorganism. Chlamydia - Secret Enemy from Past to Present examines chlamydial infections using a comprehensive multidisciplinary approach. It discusses the microbiology, clinical presentation, and current approaches in the diagnosis and treatment management of chlamydial infection from the viewpoint of different clinics as well as includes relevant and recent literature.
    Keywords: atherosclerosis ; stroke ; chlamydia trachomatis ; virulence factors ; sexually transmitted diseases ; inflammation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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  • 28
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: Catfish, one of the largest groups of freshwater fishes, are not only important ornamentals and sport fishing and research animals but also an important source of protein. This book compiles current research on this species, providing information on its production methods and uses.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences::PSVC Zoology: fishes (ichthyology)
    Language: English
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  • 29
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    IntechOpen | IntechOpen
    Publication Date: 2024-04-05
    Description: This book provides an overview of secondary metabolites in three sections: “Introduction”, “Secondary Metabolites: General Reviews and Biotechnological Interventions” and “Plant Secondary Metabolites.” It discusses the antimicrobial, anticancer, and antioxidant activities of secondary metabolites, biotechnological interventions in the production and research of secondary metabolites, and the secondary metabolites of plants.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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  • 30
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    IntechOpen | IntechOpen
    Publication Date: 2024-03-31
    Description: Protein aggregation causes malfunction in several biochemical processes. Genetic and spontaneous formations of these transmissible spongiform encephalopathies are fatal to humans and animals. Conformational change of normal form of the protein to misfolded form causes its accumulation. The misfolded infectious protein agent forms the pathogenesis of the disease. This book presents pathology of the disease along with current knowledge of the structure-activity mechanism in the first two sections. Dyshomeostasis of metals is implicated in the pathogenesis of prions, and this influence is discussed further to understand the prion mechanism. Genetic resistance and immunobiology of the disease are elaborated in the following section. Finally, a computational study on the dynamics of the prion propagation provides a structural basis of the mechanism.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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    Publication Date: 2024-04-05
    Description: Almost a decade has passed since the last textbook on the science of cryobiology, Life in the Frozen State, was published. Recently, there have been some serious tectonic shifts in cryobiology which were perhaps not seen on the surface but will have a profound effect on both the future of cryobiology and the development of new cryopreservation methods. We feel that it is time to revise the previous paradigms and dogmas, discuss the conceptually new cryobiological ideas, and introduce the recently emerged practical protocols for cryopreservation. The present books, "Current Frontiers in Cryobiology" and "Current Frontiers in Cryopreservation" will serve the purpose. This is a global effort by scientists from 27 countries from all continents and we hope it will be interesting to a wide audience.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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    Publication Date: 2024-04-05
    Description: This book examines the challenges in bioethics from medical, ethical, legal, and industrial perspectives. A critical exchange of ideas from professionals in interdisciplinary fields allows all people to learn and benefit from their far-reaching insights gained through personal and professional experiences in the fields of medicine and research. Examining these complex issues, ranging from brain-computer interfaces to disabilities in health care to the determination of death to safe injection sites, presents viable paradigms for all healthcare professionals who are being confronted with these issues today and in the future. The more we face these challenges directly, examine them critically, analyze them thoroughly, and debate them enthusiastically the more knowledge will be gained and hopefully more lives will be saved.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAD Bioethics
    Language: English
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    Publication Date: 2024-03-31
    Description: Helicobacter pylori is a universally distributed bacterium that affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease, and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book, there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacterium and studies and discussions about its aspects are welcome to the medical and scientific communities.
    Keywords: cardiovascular disease, atherosclerosis, exosomes, antibiotic resistance, endothelial dysfunction, gastric cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: This book provides in-depth insights into the diversity of actinobacteria, their various medical aspects, and their biotechnological applications. It is aimed at graduate students and researchers working with actinobacteria who need to know about recent advances in their research fields. The book, which is divided into four sections, contains 13 chapters that review the most recent methods, discuss various applications of actinobacteria, introduce some interesting results, and explore future prospects for the topics covered.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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  • 35
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    Publication Date: 2024-04-05
    Description: Iron is an essential element for numerous fundamental biologic processes. Iron-containing proteins are required for vital cellular and organismal functions including oxygen transport, mitochondrial respiration, intermediary and xenobiotic metabolism, nucleic acid replication and repair, host defense, and cell signaling. However, excess iron is toxic. This book provides a comprehensive overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, and how imbalances in iron homeostasis contribute to disease.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 36
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    Publication Date: 2024-03-31
    Description: Tropical Medicine has emerged and remained as an important discipline for the study of diseases endemic in the tropic, particularly those of infectious etiology. Emergence and reemergence of many tropical pathologies have recently aroused the interest of many fields of the study of tropical medicine, even including new infectious agents. Then evidence-based information in the field and regular updates are necessary. Current Topics in Tropical Medicine presents an updated information on multiple diseases and conditions of interest in the field. It Includes pathologies caused by bacteria, viruses and parasites, protozoans and helminths, as well as tropical non-infectious conditions. Many of them are considering not only epidemiological aspects, but also diagnostic, therapeutical, preventive, social, genetic, bioinformatic and molecular ones. With participation of authors from various countries, many from proper endemic areas, this book has a wide geographical perspective. Finally, all of these characteristics, make an excellent update on many aspects of tropical medicine in the world.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: This book discusses Trichoderma spp. and its molecular aspects and mode of action on important plant pathogens. In Brazil, there are already more than thirty-four species of this fungus registered in commercial products to control soil-borne pathogens. The book also discusses industrial use of Trichoderma. Chapters examine the application of the fungus in the integrated management of plant diseases as well as its general use in bioprocesses and even in the alcohol production industry for biofuels.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSQ Mycology, fungi
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  • 38
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    Publication Date: 2024-03-31
    Description: This book gives a comprehensive overview of recent advances in human papillomavirus (HPV) infection, as well as general concepts of infections, immunopathology, diagnosis, treatment, epidemiology, and etiology. It examines current clinical recommendations in the management of HPV, highlighting the ongoing issues, recent advances, and future directions in diagnostic approaches and therapeutic strategies. The book focuses on various aspects and properties of HPV, whose deep understanding is very important for safeguarding the human race from further loss of resources and economies due to HPV infection. I hope that this work will increase the interest in this field of research and that the readers will find it useful for their investigations, management, and clinical usage.
    Keywords: infection, cervical cancer, screening, hpv, awareness, risk factors ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: For over 70 years, dengue fever has challenged health systems in every region of the World. It has evolved from a benign febrile illness from the tropics to a major concern in urban settlements, overwhelming health infrastructure with large outbreaks, as it continues to teach us important lessons with its complexities. This book intends to review the latest updates on dengue fever, the tools available for its study and control, and promising technologies currently in the pipeline. With this work, the editors wish to provide students with an updated reference text on the basics of this disease as well as researchers and academics, with a useful document to understand the current outlook and the perspectives for the future.
    Keywords: aedes aegypti, wolbachia, epidemiology, vaccine, ecology, biosensor ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: This is an introductory book on the role of potassium in health, physiology of potassium homeostasis, diagnostic approach to potassium derangement, and clinical management of potassium disorders. It is a concise, easy-to-read reference for students in the health professions, mid-level providers, house staff trainees, and clinicians.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-04-05
    Description: Peroxisomes are cell organelles that have functions for the provision of homeostasis and sustainable cellular health. They are indispensable for lipid metabolism and free radical detoxification. A disruption in the peroxisomal pathway can cause irreparable problems or death for the organism. This book provides a comprehensive overview of peroxisomes, including their role in cell health and diseases such as cancer.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
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    Publication Date: 2024-04-05
    Description: Enterobacteriaceae are a large family of Gram-negative bacteria including Escherichia, Salmonella, Shigella, Klebsiella, Yersinia, and others. They are associated with intestinal and extra-intestinal diseases, such as urinary tract infections and diarrhea. This book examines enterobacteria with a focus on pathogenesis, virulence factors, and treatment strategies, as well as their role in multidrug resistance.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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    Publication Date: 2024-03-31
    Description: Toxoplasma gondii was first identified more than 100 years ago in the tissues of birds and mammals. Although toxoplasmosis is important all over the world, its approaches to diagnostic strategies considerably differ among countries. Its wide distribution may be attributed to complex transmission patterns and parasite coevolution with multiple hosts. Although T. gondii infections of immunocompetent people are generally considered asymptomatic, infections in immunocompromised individuals, such as those with AIDS or organ transplant recipients, can result in severe consequences. This book, composed of a series of articles, including effective diagnosis of laboratory in toxoplasma infections, congenital toxoplasmosis, relationship between toxoplasmosis and public health genomics, prevalence, genetic diversity of toxoplasmosis, and microparticle vaccines against Toxoplasma gondii by authors from all over the world, presents a wide open point of view for toxoplasmosis.
    Keywords: nanoparticles, immunotherapy, risk factors, infection, animal model, cell culture ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Even 110 years after its discovery, Chagas disease is still an important public health problem, especially in Latin America where it is endemic. The limited effect of current treatments in the chronic phase of the disease, as well as the lack of information about disease progression, are crucial challenges that justify the intense research on this illness. The interaction between the etiological agent Trypanosoma cruzi and its invertebrate and vertebrate hosts involves the regulation of the parasite virulence and host immune responses. T. cruzi presents mechanisms to evade host defenses, including resistance to oxidative species and vesicles secretion, among many others. In this context, a better understanding of the biochemical and molecular features of the parasite’s success inside its hosts could contribute to the development of novel anti-T. cruzi strategies such as prototypes of drugs and vaccines. This book discusses Chagas disease and its etiological agent, including information on relevant clinical aspects such as diagnosis, treatment, biomarkers, and so on. It also presents information about cellular, molecular, and biochemical characteristics of the parasite-host interactions.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Although there are thousands of parasites all over the world, Schistosoma spp. are unique in terms of their morphology. Although they have separate bodies as “male” and “female,” they live in such a way that the female resides within the male. Schistosoma spp., classified in the family of trematodes, has about twenty members, five of which cause a disease called schistosomiasis (or bilharzia) in humans. This disease causes a variety of symptoms, ranging from simple skin lesions to a dramatic clinical scenario of bladder carcinoma. Although there are many different diagnostic and therapeutic methods, schistosomiasis is still an important threat to humans and a significant challenge for healthcare professionals. This book discusses the morphology, geographic distribution, and evolution of Schistosoma spp., as well as the diagnosis, treatment, and prevention of schistosomiasis.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Bacterial sexually transmitted infections (STIs) are among the most widespread infections worldwide, causing major health problems. Bacterial Sexually Transmitted Infections - New Findings, Diagnosis, Treatment, and Prevention is a collection of chapters written by experts in the field from all over the globe. It includes recent scientific knowledge and advances in various approaches to the diagnosis, control, treatment, and management of bacterial STIs, depending on available resources and facilities. It presents research from the literature as well as different viewpoints to open new perspectives in this field. It is designed to improve the knowledge of those interested in bacterial STIs and new methods for their diagnosis and treatment.
    Keywords: antimicrobial resistance ; therapeutic target ; sexually transmitted diseases ; sexual abuse ; syphilis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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    Publication Date: 2024-03-31
    Description: Of all the parasitic diseases, leishmaniasis is one of the most diverse, with a variety of manifestations, from relatively minor cutaneous lesions to deadly visceral infections. It is also widespread, causing human disease in the Americas, Asia, Europe and Africa. The environments in which this disease occurs range from desert to tropical jungle to urban habitats. Not surprisingly, the literature on this disease is written in a variety of languages including Portuguese, Arabic, English and French among others. This book provides a synopsis in English of much of the recent research on leishmaniasis, with a focus on the epidemiology, diagnosis and treatment of the disease as described by researchers around the world, but with a focus on the research from Brazil and the Middle East.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: This book deals with a very common condition, anemia, which might interest not only the physicians but also other healthcare professionals and researchers dealing with anemic patients. The objective of this book was to collect and compile up-to-date information from reputable researchers of different countries of the world to disseminate the latest information about the common types of anemia in some specific physiological and pathological conditions including pathophysiology and the use of algorithms as a tool to minimize the laboratory tests and accurate diagnosis of the underlying cause. In total, there are 13 chapters in this book where the authors shared their research findings and real-life experiences in managing their patients with anemia.
    Keywords: iron deficiency, iron deficiency anemia, hepcidin, cytokines, malaria, chronic kidney disease ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: This volume presents selected issues in the complex and diverse science of animal husbandry. The use of computer programs provides an opportunity to improve breeding and optimize farm management. At the same time, the use of traditional breeding methods is also of decisive importance. Knowledge of animal welfare and animal wellness is of great help in controlling animal health issues and in economic production. In the biological processes of reproduction of dairy cows, the events of the 100 days after calving are of fundamental importance. Production systems influence the process of product production, in which the relationship between animal products and human health goes far beyond animal husbandry, and to which the issue of greenhouse gases is also connected. The quality of manufactured meat products is influenced by both on-farm and off-farm factors, but good meat cannot be produced from low-quality animals, even with excellent slaughterhouse work. Background knowledge of animal health ‒ including the microbiome in the digestive tract, which makes use of the feed ‒ makes this activity more effective, which is of particular importance in the case of broiler chickens. Knowing the behavioural characteristics of animals (rams) enables better management. Many horse breeds are capable of artificial gaits as a result of breeding and selection processes. Comparative knowledge of the movements of these horse breeds also helps to understand their differences. The quality of life of animals and the quality of manufactured products are also affected by polycyclic aromatic hydrocarbons from the environment, which, being stored and enriched in fat-containing tissues, can also have adverse effects on the human consumer. Each topic presented not only offers specialist knowledge but makes interesting reading in its own right.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences
    Language: English
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    Publication Date: 2024-03-31
    Description: The World Health Organization (WHO) estimates that 3-5 million cases of severe influenza worldwide will result in 250,000-500,000 deaths annually. Collectively, data are shared via the WHO's Global Influenza Surveillance and Response System (GISRS), which includes 143 institutions in 113 WHO member states, to help alert the emergence of antigenic variants or the beginning of a pandemic. In April 2009, the Centers for Disease Control and Prevention (CDC) cited the first incidence of human-to-human transmission of pandemic H1N1, also referred to as swine influenza A, which was antigenically distinct from other circulating human H1N1. As the first influenza pandemic of the twenty-first century, pandemic H1N1 was not included in the annual trivalent vaccine regimen, leaving a large majority of the population unprotected from the newly emerging pathogen.
    Keywords: pregnancy, nanoparticle, biosensor, pcr, vaccination, immunology ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Giardiasis is still a significant infectious and parasitic disease, caused by the protozoan Giardia intestinalis. There are estimates of more than 200 million cases of giardiasis occurred in the world annually. The advance in research in giardiasis during the last century and particularly during the last decade is considerable. Nevertheless, many challenges still are ahead in order to reach a higher control of this disease. This book tried to update the significant epidemiological and clinical research in many aspects with a multinational perspective. This book with 9 chapters has been organized in 3 major sections: 1. "Overview, Epidemiology and Clinical Aspects," 2. "Biological and Diagnostic Aspects," and 3. "Treatment, Prevention and Public Health."
    Keywords: water, epidemiology, soil, livestock, cytoskeleton, injury ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Hansen's Disease - The Forgotten and Neglected Disease provides concise information on the relevant aspects of the disease of leprosy, including immunological, epidemiological, clinical and molecular studies that are of great importance in the study of an often-ignored disease, which remains a great challenge to humanity. It collects contributions made by professional experts in the study of Mycobacterium leprae, providing perspectives with knowledge, experience and research, highlighting that the disease continues to be of interest to public health. It is expected that this book will be useful and contribute to the expansion of information and interest about the disease commonly known as leprosy.
    Keywords: leprosy, mycobacterium leprae, biomarkers, epidemiology, evolution, disability ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Mycobacterium tuberculosis in an attempt to understand the extent to which the bacilli has adapted itself to the host and to its final target. On the other hand, there is a section in which other specialists discuss how to manipulate this immune response to obtain innovative prophylactic and therapeutic approaches to truncate the intimal co-evolution between Mycobacterium tuberculosis and the Homo sapiens.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: The first roundworm identified in humans was Ascaris, described by Linnaeus in 1758. Rudolphi’s 1808 classification was the first to describe the Nematoidea. With the development of new molecular techniques, classification and phylogenetic research have also frequently changed; in 2019 a new classification, the phylum Nematoda, was created based on evolutionary relationships, developmental and morphological features and recent molecular evidence. Nematodes, which include hookworms, whipworms, threadworms, and soil-borne worms, are one of the oldest disease-causing creatures, dating back to Ancient Greek, Roman and Mesopotamian civilizations. Most commonly affecting children and women, the disease causes developmental disorders, cognitive impairment and death, with symptoms primarily affecting the organs they inhabit. In this book, the historical background, biology, transmission routes and geographical distribution of some roundworms affecting human health are discussed.
    Keywords: pathogenesis ; parasites ; investigation ; helminthiasis ; lymphatic filariasis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: Cell death is critical for embryo development and body growth. Several types of cell death have been discovered. The dysfunction of cell death is responsible for various diseases; however, the mechanism underlying cell death is not fully elucidated. Recent advances in cell death research have led to improved diagnosis, treatment, and clinical management of diverse diseases; however, novel therapeutic strategies are urgently needed. This book presents the most recent advances in cell death and related diseases.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
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    Publication Date: 2024-04-05
    Description: Cancer is a major public health problem and much research is being conducted to develop effective treatments for various types of malignancies. In doing so, researchers must have comprehensive knowledge about what causes cancer. This book explains the mechanisms of different types of cancers in twelve chapters organized into three sections on oncogenes, tumor suppressor genes, and viral oncogenes.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
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    Publication Date: 2024-04-05
    Description: Molecular docking is a widely used bioinformatics method in biology, medicine, and biochemistry. This method, which can model interactions between different receptors and their various ligands at the molecular level, can represent intermolecular interactions at an unprecedented resolution that may not be achieved by classical experimental approaches. This book describes different aspects of this method that can reveal the intermolecular biochemical and biophysical interactions and the affinities of partner molecules to each other. It is designed for academics, students, and professionals interested in this technique.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
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    Publication Date: 2024-03-31
    Description: This book contains 11 chapters of significant and updated materials on what we know and what we lack and need in better understanding of Trypanosoma cruzi - a parasite that never dies - and the consequences of Chagas disease as one of the most important neglected parasitic diseases threatening the global health and wellbeing. This book is intended to increase the readers' enthusiasm to explore the four sections of the contents: Section 1 begins with biochemistry, pathophysiology, histo-immunological study, and findings to assist in the diagnosis; Section 2 further investigates the role of vector in propagation of the parasite, the intensity on epidemiology, and the severity on clinical aspects, which help us to be well perceived on the course of disease; Section 3 is seeking beyond modern medicine and what lays in the nature that helps fight against this parasite; and the last section, Section 4, deals with the impacts of public health problem and the control strategies on Chagas disease.
    Keywords: immune system, trypanosoma cruzi, inflammation, epidemiology, chemotherapy, drug discovery ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Infective endocarditis is a potentially life-threatening devastating disease. Due to its diagnostic difficulties, definite diagnosis may be delayed. Once diagnosed, the treatment options need careful judgment preferably among team members with specialization in cardiology, imaging, infectious disease, and thoracic surgery. The purpose of this book is to cover various aspects of the management of infectious endocarditis, which may serve as a basis of knowledge that will facilitate implementation of improved, evidenced-based care for this challenging disease.
    Keywords: oxidative stress, surgery, infection, echocardiography, staphylococcus aureus, hemodialysis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: Although additives are regularly used in the food industry to improve the organoleptic properties or extend the shelf life of food products, some additives are known to be potentially hazardous if consumed in excess. Increasingly, consumers are avoiding these types of products, highlighting an overall trend toward developing a green and sustainable economy and the emergence of natural additives with equal or greater benefits than synthetic ones. This book is an introduction to the use of natural food additives. It includes eleven chapters that discuss emerging compounds used as food additives and active packaging, molecular gastronomy, enzyme production in the food industry, and much more.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
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    Publication Date: 2024-03-31
    Description: Mycobacterium tuberculosis, as recent investigations demonstrate, has a complex signaling expression, which allows its close interaction with the environment and one of its most renowned properties: the ability to persist for long periods of time under a non-replicative status. Although this skill is well characterized in other bacteria, the intrinsically very slow growth rate of Mycobium tuberculosis, together with a very thick and complex cell wall, makes this pathogen specially adapted to the stress that could be generated by the host against them. In this book, different aspects of these properties are displayed by specialists in the field.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: Increasing human migrations, technological advances, agricultural activities, and climate change are forcing plants to adapt to new environments. This book highlights current morphological, anatomical, physiological, molecular, and genomic advances in plant defense mechanisms. These advances, including epigenetic mechanisms, have been linked to observed phenotypic plant plasticity. The book also outlines next-generation food systems, considering the resilience and sustainability of plant genomes and epigenomes.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences
    Language: English
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    Publication Date: 2024-04-05
    Description: Due to climatic, social, and epidemiological challenges, urban areas are suffering from recurring problems that require profound and sustainable solutions. Although they cover only a small area of the earth’s surface, metropolises are responsible for most of the world’s global carbon emissions, which cause adverse effects on energy and the climate. This book discusses the spatial development of urban areas in the context of the United Nations Sustainable Development Goals. Chapters address the problems of large urban agglomerations, examine their impacts on both people and the environment, and propose intervention policies and strategies. The book also presents case studies from different areas of the world, including Chile, Brazil, and India.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAF Ecological science, the Biosphere
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    Publication Date: 2024-03-31
    Description: Herpesviruses are unique among viruses as they encode for a complex self-regulatory system, aggressively invade and persist in the host, evade immune defense, alter all regulatory mechanisms of the macroorganism and modify the replication of heterologous viruses. Environmental factors influence these unconventional relationships. Consequently, a single herpesvirus species can be attributed to a wide range of diseases as etiological agents or cofactors. This book is intended to give an overview on selected clinical hot topics: herpes simplex virus encephalitis, persistent infection in the gingiva, thymidine kinase gene expression causing male infertility, and pharmaceutical reactivation of Epstein-Barr virus for oncolysis. Immune evasion mechanisms and new ways to formulate vaccines are exhaustively reviewed. Finally, a surprise: bovine herpesviruses could serve as models to study the pathomechanism of herpesviruses.
    Keywords: herpesvirus, epidemiology, immunotherapy, epigenetics, innate immunity, clinical trials ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Echinococcosis is a neglected parasitic disease caused by Echinococcus spp. of the family Taeniidae. The prevalence of the disease is increasing worldwide due to industrialization and climate change. This book provides a comprehensive overview of echinococcosis, including information on epidemiology, geographic distribution, diagnosis, management, and prevention.
    Keywords: medicinal plants ; toxicity ; natural products ; pancreas ; immune evasion ; radiofrequency ablation ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Epstein-Barr virus (EBV) is a fascinating microorganism, as a “double-facetted” viral agent. After primary infection, it can persist throughout a person’s lifetime in a latent form, from which it can reactivate following specific stimuli (i.e., immunodepression). Unlike other herpesviruses, EBV reactivates a countless number of times with such a high replication rate that it is unable to be controlled by conventional anti-herpesvirus drugs. Moreover, for various reasons, no vaccine is currently available in the market. This book presents a comprehensive overview of EBV, including information on its potential for oncogenic activity, its various isolates, and possible vaccine candidates.
    Keywords: immunotherapy, vaccine, innate immunity, autoimmunity, mutation, carcinogenesis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: In this book, we propose some approaches about interrelationships between vaccine strategies and microbial epidemiology, taking into account as reference the whooping cough, an endemic disease with significant morbidity and mortality and of indisputable importance in public health.
    Keywords: epidemiology, pregnancy, infants, treatment ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: This book offers a comprehensive overview of recent trends in viral outbreaks, covering general concepts of immunobiology of infections, viral outbreaks, pathology, virology, viral genomics, viromes, and antiviral pharmacology. It also discusses current clinical recommendations for managing various viral diseases, highlighting ongoing issues, recent advances, and future directions in diagnostic approaches and therapeutic strategies. The book focuses on various aspects and properties of viral outbreaks, whose in-depth understanding is crucial to protect humanity from further losses of resources and economies due to viral diseases. It provides an overview of recent developments in the detection, monitoring, treatment, and control of several viral diseases that have caused recent epidemics or pandemics.
    Keywords: covid-19 ; pathogenesis ; aquaculture ; immunology ; virus ; endangered species ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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    Publication Date: 2024-04-05
    Description: Pectin is an industrial product of certain fruit peels that contain it, such as citrus fruits, apples, pears, grapes, plums, beets, sunflowers, and so on. It is the traditional gelling agent for jams and jellies, but its applications extend to fruit products for food, dairy, dessert, soft drink, pharmaceutical, and other industries. This book discusses pectin production, pectin biotechnology, and pectin applications. Chapters cover such topics as the production of pectin from citrus, fungal pectinases in food technology, pharmaceutical applications of pectin, and more.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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    Publication Date: 2024-03-31
    Description: This book is an annual collection of reviewed and relevant research chapters authored by various researchers, offering a comprehensive overview of recent studies and developments in the field of Infectious Diseases. It joins work from four areas in this field, Bacterial, Fungal, Parasitic, and Viral Infectious Diseases, each edited by an expert. The global challenges and different living circumstances for people around the globe ask for a deep understanding of various aspects and properties of infectious diseases to ensure a safer and healthier cohabitation of humans and pathogens.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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    Publication Date: 2024-03-31
    Description: The genus Salmonella comprises an important number of bacterial species able to colonize and infect numerous animal species and humans. Although more than a hundred years passed since its discovery, Salmonella still represents a redoubtable and successful microorganism, difficult to deal with. Whether we discuss about typhoid fever or food poisoning, the public health and financial consequences are practically incalculable. The costs attributable to Salmonella contamination of meat, eggs, and vegetables are also very high worldwide. Antimicrobial resistance in Salmonella isolates is an emerging threat not only in humans, and special measures should be addressed to this global problem. The book Current Topics in Salmonella and Salmonellosis contains a series of reviews about all-important issues concerning these subjects. It comprises 14 chapters grouped in 4 sections emphasizing new insights into pathogenesis, bacterial detection and antibiotic resistance, infections in animals, risk factors, and control strategies. The new genomic data and the exhaustive presentation of molecular pathogenesis bring novelty to the book and can help to improve our knowledge about Salmonella-induced diseases.
    Keywords: poultry, climate change, biofilm, public health, wastewater treatment, antibiotics ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: This book provides updated information on helminth infections, with proposals for new treatments and biological factors of risk, the development of vaccines for the control of helminthiasis and explains the latest research on the field. It also delves into multi-omics, diagnosis, immunology, and novel molecule targets. In addition, the book examines topics such as host-parasite interaction. Key Features: • Provides basic and clinical evidence based on molecular interactions to address the risks and benefits of helminthiasis • Presents the results of new vaccine development • Discusses new and old therapeutic approaches in helminth infections • Delves into advances in the molecular and immune response in helminth infection • Proposes a One Health approach to study helminth infections • Analyzes the controversies and confusions in the management, biology, and control strategies of helminth infections • Examines the basic biology of helminth parasites
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.
    Keywords: leishmaniasis, visceral leishmaniasis, epidemiology, apoptosis, cytokines, chemotherapy ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Advances in the understanding of neglected tropical diseases (NTDs) are inspiring the scientific community to investigate their eco-epidemiology and physiopathology, and to employ new biotechnological tools to fight against these devasting and complex infectious diseases which are associated with poverty. The topics covered include the employment of digital PCR and next-generation sequencing strategies to diagnose NTDs in hosts and reservoirs in urban and rural areas, and new findings on insects’ reproductive biology that are enabling different vector control strategies. Eco-epidemiology of arboviruses in Latin America and physiopathology of Burili disease caused by Mycobacterium ulcerans are discussed, as is molecular characterization of Plasmodium vivax circumsporozoite protein (CSP) and its use in the epidemiology of malaria and vaccine development. Finally, the origin and pathogenic role of a serine protease inhibitor of Trypanosoma cruzi (TcISP2), the causative agent of Chagas disease, are explored.
    Keywords: epidemiology ; vaccine ; dna ; trypanosoma cruzi ; flavivirus ; plasmodium vivax ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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    Publication Date: 2024-03-31
    Description: With increasing efficacy of antiretroviral therapy, HIV/AIDS has shifted from a disease with high mortality to a chronic illness with substantial longevity. However, researchers, physicians and social workers still face many challenges, and it is important to raise awareness on several aspects that people living with HIV/AIDS have to deal in their daily lives. This book has assembled an array of chapters on the medical, social and economic aspects of HIV/AIDS. The chapters were written by experts from around the globe reflecting the importance of the topic. This book will be of great interest not only to graduate students but also to active academics and practitioners.
    Keywords: hiv and aids, cancer, hiv-1, aortic aneurysm, coping strategies, qualitative study ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: Ion transporters are membrane proteins that allow the passage of ions or charged small molecules through the lipid membrane. They are present in every cell of every organism. The group of ion transporters comprises different types of ion pumps, ion exchangers, and ion channels. This book focuses mostly on ion channels, which represent the biggest subset of ion transporters. Ion transporters, especially ion channels, are of imminent interest in the field of life sciences with possible therapeutic outcomes. Each piece of knowledge that can help us understand their role and function is worth noticing. This book provides a comprehensive overview of ion channels, including their diversity and functions in physiology and pathophysiology.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
    Language: English
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    Publication Date: 2024-03-31
    Description: Echinococcosis is an important zoonotic helminth disease all over the world, since some forms may be fatal. The most common species leading to echinococcosis are Echinococcus granulosus, Echinococcus multilocularis, Echinococcus vogeli, and Echinococcus oligarthrus. Although it has been known for many years, it keeps its interesting features. In this book, we aimed to update our knowledge on echinococcosis, focusing on current research advances, new horizons for drug therapy, and surgical management including surgical complications. I cordially believe that this book on echinococcosis will also motivate the future scientists to accomplish more studies on this issue.
    Keywords: drug discovery, hydatid cyst, echinococcus, prevention, echinococcus multilocularis ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: This textbook includes the recent progresses and scientific knowledge from the leading experts in different approaches to control, diagnosis, and management depending on resources and facilities available. This book has been written by our colleagues from all over the world. This book is divided into six sections. Each section supplies particularly sexually transmitted infections, diagnostics, microorganism types, pathogenesis, and treatment options. Essential points in publishing this book are to improve our knowledge about sexually transmitted infections and new treatment modalities. One chapter of the book is devoted to viral infections and their treatment. We think that this textbook will serve as a comprehensive guide to many physicians dealing with sexually transmitted infections in their clinical practice. It will hopefully be a precious source for dermatologists, educators, other physicians, and medical students.
    Keywords: hpv, sexually transmitted diseases, cancer, hiv, ethics, cervical cancer ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: This book discusses RNA viruses and their potential to cause pandemics, such as the coronavirus pandemic the world is currently experiencing. It discusses different types of RNA viruses, including SARS-CoV2, respiratory syncytial virus (RSV), influenza, HIV, and others. Chapters examine the epidemiology, transmission, pathogenesis, diagnosis, prevention, and control using the One Health approach.
    Keywords: Clinical & internal medicine ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Tuberculosis is an ancient disease with a high incidence and mortality rate, unequally distributed worldwide. Epidemiological indicators, but also risk factors, play a key role in the natural history of the disease and need to be regulary addressed. Low and middle income countries are not prepared for appropriate response and are also the most affected. The incidence of this extrapulmonary disease is far from being clearly established. Epidemiological studies in different geographical areas will help in this field.
    Keywords: epidemiology, cytokines, infection, immunology, chemokines, carcinoma ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-04-05
    Description: Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.
    Keywords: Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)
    Language: English
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    Publication Date: 2024-03-31
    Description: This book covers the different aspects of non-flavivirus encephalitises of different ethiology. The first section of the book considers general problems of epidemiology such as study of zoonotic and animal vectors of encephalitis causative agents and methods and approaches for encephalitis zoonoses investigations. The members of different virus species are known to be the causative agents of encephalitis, so the second section of the book is devoted to these viral pathogens, their epidemiology, pathology, diagnostics and molecular mechanisms of encephalitis development by such viruses as HIV/SIV, herpes simplex virus type 1 and equine herpesvirus 9, measles virus, coronaviruses, alphaviruses and rabies virus. The next section of the book concerns the study of protozoan pathogens such as toxoplasma and amoebae. The last section of the book is devoted to multicellular pathogen as human Filaria Loa Loa - a filarial worm restricted to the West Africa.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Generally, in accordance with anatomical characteristics, urinary tract infections (UTIs) and in particular recurrent UTIs occur in women; in contrast, UTIs normally occur in men with different predisposing factors. There are several types of UTIs, including asymptomatic and symptomatic, complicated and uncomplicated, acute and chronic with a diversity of microbial pathogens. In pathogens, virulence factors and genes determine the type and severity of the UTIs. Obviously, UTIs are a huge problem in global public healthcare systems with a wide range of predisposing factors, including gender, microbial agent, the host's immune deficiencies, genetic diseases, catheterization, etc. The recent items determine the microbiology of UTIs. Accurate diagnosis and definitive treatment are the key to UTI reduction.
    Keywords: diabetes mellitus, biofilm, antimicrobial resistance, e. coli, antibiotic, genotypes ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Escherichia coli is a versatile organism and very diverse. Members of this species vary from very pathogenic agents causing different types of diseases including meningitis, gastroenteritis, and septicemia, just to cite a few, to harmless organisms living in the intestines of both humans and animals. E. coli has also been used as a model organism for most bacteria except a few. For this reason, its study provides a huge advantage and can help understand the mechanisms involved in different processes such as pathogenesis, environmental disinfection, nutrient utilization, antibiotic resistance, and diagnostic/detection methods, and these are indeed the topics discussed in this book. The book has been divided into four main sections representing the different facets of E. coli applications, which include disease, biotechnology, environmental engineering and innovative approaches to detection, and lastly its physiology and cell biology. Such processes can be applied to the study of other organisms as well considering the development of diversity; for example, many organisms are capable of horizontal gene transfer, which is capable of increasing the fitness of the bacterial organisms involved and has a great impact on the control of such bacterial organism.
    Keywords: antimicrobial resistance, biosensors, e. coli, virulence factors, nanocomposites, biofilm ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Mycobacterium tuberculosis is a disease that is transmitted through aerosol. This is the reason why it is estimated that a third of humankind is already infected by Mycobacterium tuberculosis. The vast majority of the infected do not know about their status. Mycobacterium tuberculosis is a silent pathogen, causing no symptomatology at all during the infection. In addition, infected people cannot cause further infections. Unfortunately, an estimated 10 per cent of the infected population has the probability to develop the disease, making it very difficult to eradicate. Once in this stage, the bacilli can be transmitted to other persons and the development of clinical symptoms is very progressive. Therefore the diagnosis, especially the discrimination between infection and disease, is a real challenge. In this book, we present the experience of worldwide specialists on the diagnosis, along with its lights and shadows.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: The discovery of Salmonella in swine in 1885 marked the beginning of intense efforts to control salmonellae that have continued for the past 127 years. The majority of foodborne outbreaks are caused by only a few of the 2500+ known serovars. While progress has been made on many fronts, salmonellosis has yet to be eliminated in either developed or in developing nations. This work represents the collective contributions of authors from all around the world. Chapters in this book address a wide array of topics related to understanding and controlling this pathogen, including: Salmonella as studied in the environment, air and in food products; virulence and pathogenicity; control by bacteriophages and other antimicrobials; bacterial adaptation; etc.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: Human immunodeficiency virus (HIV) infection is a complex illness affecting the immune system. Acquired immunodeficiency syndrome (AIDS) is an advanced form of HIV infection in which the patient has developed opportunistic infections or certain types of cancer and/or the CD4+ T cell count has dropped below 200/μL. More than 40 million persons around the world are infected with HIV, with approximately 14,000 new infections every day. The disease causes 3 million deaths worldwide each year, 95% of them in developing countries. Optimal management of human immunodeficiency virus requires strict adherence to highly active antiretroviral treatment (HAART) regimens, but the complexity of these regimens (e.g., pill burden, food requirements, drug interactions, and severe adverse effects) limits effective treatment. However, more patients with HIV are surviving longer today because of these drugs. This allows further study of commonly associated adverse effects. These may affect all body systems and range from serious toxicities to uncomfortable but manageable events. This book reviews some of HAART-related metabolic and neurological complications.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
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    Publication Date: 2024-03-31
    Description: In 1957, a Streptomyces strain, the ME/83 (S.mediterranei), was isolated in the Lepetit Research Laboratories from a soil sample collected at a pine arboretum near Saint Raphael, France. This drug was the base for the chemotherapy with Streptomicine. The euphoria generated by the success of this regimen lead to the idea that TB eradication would be possible by the year 2000. Thus, any further drug development against TB was stopped. Unfortunately, the lack of an accurate administration of these drugs originated the irruption of the drug resistance in Mycobacterium tuberculosis. Once the global emergency was declared in 1993, seeking out new drugs became urgent. In this book, diverse authors focus on the development and the activity of the new drug families.
    Keywords: Infectious & contagious diseases ; thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCJ Infectious and contagious diseases
    Language: English
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