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  • Books  (4)
  • Cell & Developmental Biology
  • Genetics
  • Karger  (2)
  • Springer Nature  (2)
  • American Association for the Advancement of Science
  • American Institute of Physics (AIP)
  • American Physical Society
  • CRC Press
  • Oxford University Press
  • Wiley-Blackwell
  • 2020-2024  (4)
  • 2005-2009
  • 1990-1994
  • 1985-1989
  • 1960-1964
  • 1935-1939
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  • 2020-2024  (4)
  • 2005-2009
  • 1990-1994
  • 1985-1989
  • 1960-1964
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  • 1
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    Statistical Population Genomics (2021)
    Springer Nature
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    Publication Date: 2024-04-06
    Description: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions.
    Keywords: Life sciences ; Bioinformatics ; Genetics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
    Language: English
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  • 2
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    Evolutionary Genomics (2021)
    Springer Nature
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    Publication Date: 2024-04-05
    Description: This open access book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results. Authoritative and comprehensive, Evolutionary Genomics: Statistical and Computational Methods, Second Edition aims to serve both novices in biology with strong statistics and computational skills, and molecular biologists with a good grasp of standard mathematical concepts, in moving this important field of study forward.
    Keywords: Life sciences ; Bioinformatics ; Genetics ; Evolutionary biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAJ Evolution ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
    Language: English
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  • 3
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    Aging and Health (2021)
    Karger
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    Publication Date: 2024-04-01
    Description: Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging.
    Keywords: Medicine & Public Health ; Gerontology ; Geriatrics ; Genetics ; Bioinformatics ; Genomics ; Physiology ; Medicine ; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKN Geriatric medicine
    Language: English
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  • 4
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    Personalized Nutrition (2021)
    Karger
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    Publication Date: 2024-03-31
    Description: Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the ‘3rd Congress of the International Society of Nutrigenetics/Nutrigenomics’ held in Bethesda, Md., in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included.
    Keywords: Medicine & Public Health ; Nutrition ; Genetics ; Clinical Nutrition ; Dietetics ; Obesity ; Oncology ; Medicine ; thema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFN Medical genetics
    Language: English
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