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  • Biotechnology.  (77)
  • Cham :Springer International Publishing :  (77)
  • Presses universitaires de Rennes
  • 2020-2024  (77)
  • 2022  (77)
  • 1
    Keywords: Water. ; Hydrology. ; Refuse and refuse disposal. ; Environmental management. ; Environmental chemistry. ; Biotechnology. ; Water. ; Waste Management/Waste Technology. ; Environmental Management. ; Environmental Chemistry. ; Biotechnology.
    Description / Table of Contents: Recent Developments in Membrane Filtration for Wastewater Treatment -- Ultrafiltration membrane water treatment system: An overview -- Ultrafiltration Integrated Photocatalytic Membrane Systems in Water and Wastewater Treatment: An Overview -- Application of electrospun polymeric nanofibrous membranes for water treatment -- Biosorbents in industrial wastewater treatment -- Nanoparticles in industrial wastewater treatment: An overview.
    Abstract: This book provides an overview of recent advances in technologies for water treatment processes, such as green technology, nano-adsorbents, photocatalysts, advanced oxidation, membranes separation and sustainable technologies. Advances in membrane technology and fabrication process is presented in detail. Latest approaches like microbial treatment, electro chemical and solar energy-based treatment techniques were presented. Also, the use of sustainable and energy efficient approaches were discussed. The book presents the negative impact of inorganic and organic pollutants on the natural environment and human health. It describes and discussing the advanced membrane technologies, novel green adsorbents, microbial treatment techniques, electro chemical and solar based removal techniques It also compares the most effective methods of removing toxic contaminants from water solutions with the use of sustainable and energy efficient approaches It also presents the life cycle assessment of emerging technologies in industrial wastewater treatment and desalination as well as presents the benchmarking of energy efficiency during treatment process.
    Type of Medium: Online Resource
    Pages: VIII, 475 p. 97 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030982027
    Series Statement: Water Science and Technology Library, 106
    DDC: 551.48
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Pharmacology. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Pharmacology.
    Description / Table of Contents: Chapter 1. Botanical Features of Periwinkle, Catharanthus roseus -- Chapter 2. Catharanthus roseus: A Source of Anticancer Phytomedicines -- Chapter 3. Classical Breeding and Trait Genetics in Catharanthus -- Chapter 4. Somatic Embryogenesis in Catharanthus roseus: Proteomics of Embryogenic and Nonembryogenic Tissues; and Genome Size Analysis of Regenerated Plant -- Chapter 5. Alkaloid Synthesis in in vitro Cultures of Catharanthus roseus: Capabilities and Limitations -- Chapter 6. Genetic Transformation in Catharanthus roseus -- Chapter 7. Molecular Markers and Descriptor’s Suitable for Quantitative Trait Loci and Genome Mapping in Catharanthus roseus -- Chapter 8. Sequencing the Genome of Catharanthus roseus: Status and Prospects -- Chapter 9. Functional Genomics Approaches for Gene Discovery Related to Terpenoid Indole Alkaloid Biosynthetic Pathway in Catharanthus roseus -- Chapter 10. Future Prospects for Research on Catharanthus roseus.
    Abstract: This book is the first comprehensive compilation of deliberations on botany, medicinal importance, genetic diversity, classical genetics and breeding, in vitro biosynthesis, somatic embryogenesis, genetic transformation, molecular mapping, genome sequence, and functional genomics of Catharanthus roseus. Catharanthus is the most important medicinal plant in the world that contains about 130 therapeutic alkaloids out of which vinblastine and vincristine are the two highly used anticancer drugs sold by the pharmaceutically industries. Altogether, the book contains about 10 chapters authored by globally reputed experts on the relevant field of this plant. This book is useful to the students, teachers and scientists in the academia and relevant private companies interested in horticulture, genetics, breeding, pathology, entomology, physiology, molecular genetics and breeding, in vitro culture and genetic engineering, and structural and functional genomics. This book is also useful to pharmaceutical industries.
    Type of Medium: Online Resource
    Pages: XXV, 183 p. 86 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030892692
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 3
    Keywords: Botany. ; Environment. ; Biotechnology. ; Renewable energy sources. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Plant Science. ; Environmental Sciences. ; Biotechnology. ; Renewable Energy. ; Fossil Fuel.
    Description / Table of Contents: Introduction: values of pollution free atmosphere -- Plant and Algae Classes Recognition, Biomass Production and Potential Source of Biofuel -- Plant and Algae Metabolites Alternative and Clean Source of Energy -- Mechanism and methods of extraction of biofuels -- Metabolic routes to biofuels extraction -- Optimizations on steps involved on biofuel obtainment and their validation -- Economic consideration on biofuel and energy security -- Technical challenges of biofuel obtainment -- Conclusion and Future Perspectives.
    Abstract: This volume discusses how plant and algae organisms play a pivotal role in the transformation of solar energy to essential metabolites, and explores the numerous beneficial roles these metabolites have at an industrial level. It presents information on the utilization of plant and algae for biomass production, and shows how this is a practical option for large scale biofuel production. The book examines how these bio-metabolites can then be used to extract biofuel. Biomass produced from plants and algae can act as the source of feedstock for biofuel production and industrially important compounds. This book also explores that by curtailing culturing cost using wastewater, seawater, and industrial water as a nutrient and water source, biomass becomes an economical energy source. The introductory chapters of the book focus on the appreciative values of a pollution-free atmosphere, with special reference to enhanced greenhouse effect, and then are followed by chapters on the potential of plant and algae as a liquid energy resource. This book targets researchers, graduate students, and energy and fuel industry professionals interested in the plant sciences, biotechnology and renewable energy. .
    Type of Medium: Online Resource
    Pages: XV, 164 p. 21 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030940744
    DDC: 580
    Language: English
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  • 4
    Keywords: Water. ; Hydrology. ; Earth sciences. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Natural disasters. ; Sustainability. ; Water. ; Earth Sciences. ; Environmental Engineering/Biotechnology. ; Natural Hazards. ; Sustainability.
    Description / Table of Contents: Performance improvement of usbr vi stilling basin model for pipe outlet -- Rain water harvesting for the main campus of jaipur national university, jagatpura, Jaipur -- Bio Inspired Genetic Algorithm for Optimal Design of Water Distribution Networks -- Drought assessment using various drought indices: a case study of banaskantha district -- Top surface soil moisture retrieval using c- band synthetic aperture radar over kudremukh grasslands -- Meteorological drought assessment in the bharathapuzha river basin -- Experimental and numerical analysis of mean pressure coefficient on C-shaped building with and without round corner. .
    Abstract: This book carefully considers hydrological models which are essential for predicting floods, droughts, soil moisture estimation, land use change detection, geomorphology and water structures. The book highlights recent advances in the area of hydrological modelling in the Ganga Basin and other internationally important river basins. The impact of climate change on water resources is a global concern. Water resources in many countries are already stressed, and climate change along with burgeoning population, rising standard of living and increasing demand are adding to the stress. Furthermore, river basins are becoming less resilient to climatic vagaries. Fundamental to addressing these issues is hydrological modelling which is covered in this book. Integrated water resources management is vital to ensure water and food security. Integral to the management is groundwater and solute transport, and this book encompasses tools that will be useful to mitigate the adverse consequences of natural disasters.
    Type of Medium: Online Resource
    Pages: X, 526 p. 289 illus., 219 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030813581
    Series Statement: Water Science and Technology Library, 109
    DDC: 551.48
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Environmental management. ; Agriculture. ; Bioclimatology. ; Sustainability. ; Biotechnology. ; Environmental Management. ; Agriculture. ; Climate Change Ecology. ; Sustainability. ; Biotechnology.
    Description / Table of Contents: Part I Introduction -- Part II Impact of Climate Change on Crop Production -- Part III Case Studies: Improve Crop Adaptability and Stability to Climate Change -- Part IV Conclusions and Recommendations.
    Abstract: This book presents case studies based on sustainable agriculture in Egypt and how this is effected by climate change. The book is divided into four parts consisting of ten chapters. The first part of the book includes an introduction to the crop productivity, biotechnology and climate change. The second Part consists of two chapters dealing with crop production with a focus on critical periods of crop plants response to stress conditions and the quality of field crops. The third chapter highlights the foundations of crop tolerance to environmental stress and plant traits relevant to stress tolerance. It is devoted to explaining and discussing mechanisms of adaptation to environmental stress conditions and addresses various plant traits related to stress environmental tolerance i.e. phenological, morpho-physiological and biochemical traits which could be used as selection criteria for crops improvement. The third Part consists of five chapters under the theme “Improve Crop Adaptability and Stability to Climate Change and Modern Technology". Chapter 4 highlights the most important strategic food grain crop (wheat). Chapter 5 focuses on the important staple food crop (rice), while Chapter 6 deals with one of the most important food legume crops (faba bean). Chapter 7 and 8 discuss two important oil crops (sesame and sunflower). However, Chapter 9 focuses on cotton as one of the most important fiber crops. These crops are addressed under the following headings: genotype x environment interaction and its relation to climatic change on yield production, performance of genotypes in response to environmental changes, adaptability and yield stability to environmental conditions, additive main effects and multiplicative interaction model, gene action, genetic behavior and heritability for traits related to environmental stress tolerance, role of recent approaches, biotechnology and nanotechnology. Additionally, it is considered how to measure sensitivity of genotypes to environmental stress, and finally the appropriate agricultural practices to mitigate environmental stress on crops under attention. The book ends with Chapter 10 which provides an update of the book topics, present the most important conclusions and recommendations from all chapters. This book has been prepared and supported by recent references and statistics including full-coloured tables and illustrations. The book is written for those interested in crop science, environment, plant breeding, genetics and biotechnology, as well as postgraduate students and researchers in universities and research centres.
    Type of Medium: Online Resource
    Pages: XIII, 320 p. 40 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030818739
    DDC: 333.7
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Genetics. ; Biotechnology. ; Agriculture. ; Plant Science. ; Genetics and Genomics. ; Biotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. The Broomcorn Millet Genome -- Chapter 2. Buckwheat Genome and Genomics -- Chapter 3. Tef [Eragrostistis tef (Zucc.) Trotter] -- Chapter 4. The Apricot Genome -- Chapter 5. Chinese Jujube: Crop Background and Genome Sequencing -- Chapter 6. The Longan (Dimocarpus longan) Genome -- Chapter 7. The Mangosteen Genome -- Chapter 8. The Passion Fruit Genome -- Chapter 9. The Soursop Genome (Annona muricata L., Annonaceae) -- Chapter 10. Underutilised Fruit Tree Genomes from Indonesia -- Chapter 11. The Bambara Groundnut Genome: From the Crop to the Genome -- Chapter 12. Grasspea -- Chapter 13. The Lablab Genome -- Chapter 14. The Perennial Horse Gram (Macrotyloma axillare) Genome, Phylogeny, and Selection Across the Fabaceae -- Chapter 15. Breeding and Genomics of Pigeonpea in the Post-NGS Era -- Chapter 16. Rice Bean -- Chapter 17. The Winged Bean Genome: One Species Supermarket -- Chapter 18. Castor Bean: Recent Progress in Understanding the Genome of this Underutilized Crop -- Chapter 19. Genome Resources for Ensete Ventricosum (enset) and Related Species -- Chapter 20. Yam Genomics -- Chapter 21. The African Eggplant -- Chapter 22. Sequencing of the Bottle Gourd Genomes Enhances Understanding of the Ancient Orphan Crop -- Chapter 23. Advances and Prospects in Genomic and Functional Studies of the Aquatic Crop, Sacred Lotus -- Chapter 24. Utilising Public Resources for Fundamental Work in Underutilised and Orphan Crops.
    Abstract: This book highlights the uses for underutilized crops, presenting the state-of-the-art in terms of genome sequencing for over 30 crops, previously understudied and under-researched. In a changing climate and with significant pressure on the land, it is the ideal time to be discussing novel crops, with significant biotic and abiotic tolerances and/or rich nutrient profiles for consumers. Previously, the only species with sequenced genomes were high-profile internationally recognized crops, but in the current era genomes are being sequenced for dozens of crops, including those previously classified as underutilized, now being investigated. This book covers food crops, from fruits to tubers, and from grasses to legumes, as well as crops with non-food applications. Some of these crops have draft genomes, and others have polished genomes with extensive resequencing panels. Each chapter tells the story of an individual crop or crop group, written by experts, focusing on the genome data available, revealing more about crop domestication and genetic variation, and the current and future prospects given that this data is now becoming available. It also highlights how even small sequencing projects can provide draft genome sequences suitable for gene discovery, comparative genomics, and identification of molecular markers for understanding these crops further.
    Type of Medium: Online Resource
    Pages: XXIV, 450 p. 125 illus., 105 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031008481
    Series Statement: Compendium of Plant Genomes,
    DDC: 580
    Language: English
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  • 7
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Entrepreneurship. ; New business enterprises. ; Public health. ; Biotechnology. ; Biomedical Research. ; Entrepreneurship. ; Public Health.
    Description / Table of Contents: Part I. What Is Wrong with Health? What Should the Future of Health Be? -- INNOVATION DESIGN for the FUTURE of HEALTH -- Health Innovations from an Innovators’ Perspective -- From SICKCARE to HEALTHCARE to HEALTH -- Future Look on Health: Opportunities -- Navigating Towards a Future of “One Health” -- Part II. Exponential Medicine + Technologies + Mindset -- Exponential Technologies for an Exponential Medicine -- Exponential Medicine: Challenges of Human Spaceflight Bringing Innovations for Earth—A Case Study -- Healthy Longevity -- The Science of Health Longevity -- Space Healthtech: Innovation Base for Longevity -- Part III. Future Health Value Propositions -- Healthcare the Melting Pot of Technology, Humanity, and Confusion -- Democratize Health Delivery -- Health Innovation Process: Definitions and Short Methodology Introductions -- Prevention, Prediction, Personalization, and Participation as Key Components in Future Health -- Digital Health Business Models: Transformation Is on the Horizon -- Value Propositions for Future Health Developments: Digital, Portable, Connected, Experience-Enhancing, Supportive, Patient-Centric, and Affordable -- (Digital) Patient Journey and Empowerment: Digital Twin -- Part IV. Innovation Methodology Basics -- Stanford Biodesign as Base: Empathy and Patient Centricity as the Main Driver -- Purpose Launchpad Methodology: Introduction -- Design Thinking for Innovations in Healthcare -- VPC to BMC to Exponential Canvas: Canvas Interconnectivity for Exponential Scaling -- Innovation Methodology I3 EME: Awareness for Biomedical Engineers -- Part V. Ethics + Health Innovation -- Integrating Ethical Considerations into Innovation Design -- Part VI. Health Innovation Design -- Case Studies Used Throughout the Book: Innovation Categories Explained -- Why Is Healthcare Different with Respect to Innovation and Entrepreneurial Activities? -- Purpose Launchpad Health (PLH) Methodology Introduction -- Part VII. Purpose Launchpad Health -- Purpose Launchpad Health: Exploration and Evaluation Phases—Actual Case Studies -- Part VIII. Health Leadership, Skills and other Methodologies -- Soft Skills Needed for Problem Understanding and Innovation Generation -- Leadership in Healthcare: A Novel Approach. Healthcare Executives’ Traits, Styles, and Approaches -- Future Skills Framework in Healthcare -- Porter’s Five Forces Analysis: Quo Vadis Immunotherapy Industry -- Part IX. Health Entrepreneurship -- Global Health Markets and Their Different Needs -- Patient: Health Relation and Digital Health Entrepreneurship -- Health Start-Up: Create Impact and be Investment Ready Intra- and Entre-Preneurs -- Regulatory Issues for Health Innovations -- Innovation Think Tank Frameworks for Resolving “The Innovator’s Dilemma” in Healthcare -- A Primer on Patents and IP for Health Innovations -- Successfully Implementing Ambidexterity in the Medical Industry -- Reverse Innovation: Circumvent Digital Health Transformation Issues -- Part X. Health Innovation Education and Incubation -- Health Innovation Design: “CAMPing” for the Unmet Clinical Need -- Health Technology Innovation Generation (HTIG) Lecture and Project Classes at AGH University -- Health Innovation Design at a University: INKA INNOLAB at Otto-von-Guericke-University -- Clinical Innovation at Acibadem Biodesign Center -- Example of a Needs-Driven Innovation Training Program: The BioMedical Design Novo Nordisk Foundation Fellowship Program -- Addressing the Healthcare Needs with Innovation Think Tank Global Infrastructure and its Methodology -- The Power of a Collaborative Ecosystem: Introducing the Edison™ Accelerator -- HealthTec Networks and Clusters (Global): Innovation Clusters in Medtech in Europe -- Leadership-Compass: “Networking and Synapting Empowered by Health Captains” -- Part XI. Purpose Launchpad Health: Toolset Templates and Principles -- PLH Templates and Principles.
    Abstract: This book highlights the reasons for an urgently needed revision of the current global healthcare setup, discusses the needed mindset for a future of health, and provides a comprehensive development toolset for disruption (and for the needed incremental innovations towards disruption). Today’s biomedical and health innovation related research in universities encourages activities that lead to incremental innovations with a relatively low risk of failure. The healthcare industry on the other hand provides tools and devices for established healthcare providers to improve the diagnosis and therapy/ treatment of the patients’ health problems. The patient is not in the center of healthcare provision however, and prevention and prediction are not core goals. The current health setup needs to be challenged and disrupted. Disruptions are coming from technologies or processes that lead to a significant (〉10x) reduction in cost or price/ performance and that also come with new business models. The need for change, effects of exponential technologies, and the needed shift to prevention and to homecare for health democratization and patient empowerment will be discussed in detail in the first parts of the book. The subsequent sections address several innovation methods with a focus on a novel meta methodology named Purpose Launchpad Health. This is followed by a comprehensive discussion on health entrepreneurship activities and needs. The final section of the book addresses how to train students to become entrepreneurial health innovators, presenting successful curricula and examples of health incubation and accelerator setups. All of the innovation tools presented and used in this book are summarized in the final chapter to help the reader get started planning an entrepreneurial venture. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments. Chapters are concise and enriched with key messages, learning objectives and real innovation examples to bridge theory and practice. This book aims to serve as a teaching base for health innovation design and to prepare for health-related entrepreneurial ventures. Readers with medical, biomedical, biotechnology, and health economics backgrounds - and anyone who wants to become a future oriented health innovator or who believes in disruptive approaches - will find this book a useful resource and teaching tool for developing validated products/ services and processes for the future of health.
    Type of Medium: Online Resource
    Pages: XXXIV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031081910
    DDC: 660.6
    Language: English
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  • 8
    Keywords: Fungi. ; Mycology. ; Microbiology. ; Medical microbiology. ; Biodiversity. ; Plant ecology. ; Plants Evolution. ; Biotechnology. ; Fungi. ; Medical Microbiology. ; Biodiversity. ; Plant Ecology. ; Plant Evolution. ; Biotechnology.
    Description / Table of Contents: Preface -- Climate change overview -- Fungi: Essential elements in ecosystems -- Thermotolerance and adaption to climate change -- Impact of climatic change on dermatophytosis -- Climate change and the proliferation of cases of sporotrichosis -- Climate change and eumycetoma -- Effect of climate change on the geographical distribution of coccodioidomycosis -- Geographical expansion of histoplasmosis and its relation to climate change -- Impact of climate change on opportunistic mold infections -- The emergence of opportunistic yeast infections and climate change -- Climate change and allergies -- Climate change and mycotoxins -- Mycosis in natural disasters associated with climate change -- Advances and limitations in the identification of fungi -- Actions against the increase in fungal infections due to climate change: Prospects for vaccine development -- Bibliography -- Index.
    Abstract: The shift of weather patterns has affected the incidence and prevalence of infectious diseases, including mycoses. Mycoses have remained neglected due to a lack of training and recognition within the medical community. Nonetheless, these diseases remain common worldwide while frequently being underdiagnosed. Climate change affects the distribution of fungal communities, provoking outbreaks in locations where these mycoses were absent or in low frequencies. Moreover, the reports of clinical cases related to new fungal pathogens have increased due to the description of new fungal species or due to the ability of some species to shift to new hosts. Thus, this book, The Impact of Climate Change on Fungal Diseases, is a contribution to the knowledge of a global environmental phenomenon and its relation to these diseases, and it serves as a guide for health professionals to dive deep into the repercussions of climate change and how they can implement measures for the prevention and control of fungal infections.
    Type of Medium: Online Resource
    Pages: XV, 305 p. 43 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030896645
    Series Statement: Fungal Biology,
    DDC: 579.5
    Language: English
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  • 9
    Keywords: Biotechnology. ; Biomaterials. ; Biology Technique. ; Biotechnology. ; Biomaterials. ; Biological Techniques.
    Description / Table of Contents: Introduction to Biobanking -- Scientific Relevance, Problems and the Destitution for Principles of Biobanks and Biobanking Activities -- Types of Biobanks -- Ethical and Legal Principles in the Field of Biobanking -- Business Planning for Biobanks -- Biobanking Concepts Specific for Developing Countries -- Methods of Implementation and Set-up of National Biobanking Networks -- Implementation of Ethical and Legal Considerations in a Biobanking Network -- Collection and Management of Samples -- Quality Control and Risk Management in Biobanks -- Governance and Stakeholder Analysis -- Biobanking IT Systems, Database Structure and Web Applications -- Management Model and Sustainability Plan of Biobanks -- Sustainability Plan and Project Management of a Biobanking Network -- Establishing a Biobank Using Standardisation -- Science and Innovation of Biobanks -- Running a Biobank Network -- Infrastructure: Delivering on the Promise of Biobanking -- Design Considerations and Equipment of Biobanks -- Software Tools for Biobanking in LMICs -- The Importance of Cancer Biobanks in Low- and Middle-Income Countries -- Biobanking in Paediatrics: A Look from Armenia as a Middle-Income Country -- Biobanking of the Central Nervous System -- The Importance of Biobanking COVID-19 Samples -- Oncobiobanking in a Middle-Income Country: The Example of Russia -- Sustainability of Biobanks and Biobanking in LMICs -- Biobanks for Enabling Research and Development by Trusted Patient Data Environment -- Future Perspective of the Biobanking Field.
    Abstract: This book introduces the fundamentals of biobanking and guides through the practical planning thereof, with a special focus on the situation in low- and middle-income countries. On the example of the setup of a Ukrainian biobank the book discusses the main steps and aspects of successful biorepository implementation and management. Topics covered include collection, storage and shipping of samples, establishment of an IT system, development of a sustainability plan, and project and risk management. Furthermore, the importance of the formation of international biobanking societies such as the Ukraine Association of Biobanks is highlighted, and their main objectives and tasks are discussed. The book addresses life science and business professionals as well as national authorities who are interested in biobanking in general and in setting up a biobank in particular.
    Type of Medium: Online Resource
    Pages: XVII, 235 p. 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030876371
    DDC: 660.6
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Stem cells. ; Biotechnology. ; Biomedical Research. ; Stem Cell Biology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. The historical studies underpinning the concept of hair follicle neogenesis (Higgins C, Jahoda C) -- Chapter 2. Hair regeneration and rejuvenation: pipeline of medical and technical strategies (Limbu S, Kemp P) -- Chapter 3. Cells and structures involved in hair follicle regeneration: an introduction (Tsai J, Garza LA) -- Chapter 4. The dermal papilla and hair follicle regeneration: Engineering strategies to improve dermal papilla inductivity (Pantelireis N, Clavel C) -- Chapter 5. Dermal sheath and hair follicle regeneration (Yoshida Y, Tsuboi K, Kishimoto J) -- Chapter 6. Epithelial-mesenchymal interactions between hair follicles and dermal adipose tissue (Ramos R, Plikus MV) -- Chapter 7. Lymphatic vasculature and hair follicle regeneration (Cazorla A, Perez-Moreno M) -- Chapter 8. In vitro and ex vivo hair follicle models to explore therapeutic options for hair regeneration (Bertolini M, Piccini I, McElwee KJ) -- Chapter 9. Extracellular vesicles including exosomes for hair follicle regeneration (Aberdam E, le Riche A, Bordes S, Closs B, Park BS, Aberdam D) -- Chapter 10. Stem cell-based therapies for hair loss: what is the evidence from a clinical perspective? (Park BS, Choi HI) -- Chapter 11. Induced pluripotent stem cell approach for hair follicle regeneration (Pinto A, Terskikh AV) -- Chapter 12. Biofabrication technologies in hair neoformation (Abreu CM, Gasperini L, Marques AP) -- Chapter 13. Wound healing induced hair follicle regeneration (Jiang Y, Myung P) -- Chapter 14. Hair follicles in wound healing and skin remodeling (Plotczyk M, Jimenez F) .
    Abstract: This book aims to comprehensively review the current cell-based strategies under investigation to achieve the regeneration of human hair follicles. The unique capacity of the human hair follicle to self-renew explains why this complex “mini-organ” has always attracted so much interest as a model for researchers to study stem cell biology and regenerative medicine. The hair follicle is considered a main reservoir of cutaneous stem cells, containing several pools of epithelial, melanocyte, and mesenchymal stem cells involved in hair follicle self-regeneration and pigmentation. In addition, while some of the different follicular cell types contribute to hair shaft growth, others participate in very important interfollicular functions such as dermal remodeling, re-epithelialization after wounding, and cutaneous stem cell homeostasis. The idea of human hair follicle regeneration either “de novo” or by activating dormant miniaturized follicles is not new, yet still continues to arouse enormous interest in the pursuit of a definitive cure for baldness. In contrast to hair follicle regeneration in mice, the attempts made with human follicles have been disappointing in terms of efficiency. However, recent advances in stem cell biology—as well as the appearance of new technologies like 3D printing—have revived expectations in this field of research. This book is divided into four sections. The first part includes an overview of the strategies used in hair follicle regeneration and a historical summary of the most important achievements to date. Parts two and three comprise the main body of the book, with detailed descriptions of the cells and tissue structures involved in hair follicle regeneration, followed by an elaboration of the different therapeutic strategies, engineering techniques, and a clinician’s perspective of stem cell-based therapies in hair loss treatments. Finally, the fourth part reviews the important contribution of the hair follicle in healing cutaneous wounds through the regeneration and remodeling of the dermis and epidermis after injury, as well as wound induced hair follicle neogenesis that occurs when the skin is injured.
    Type of Medium: Online Resource
    Pages: XII, 307 p. 73 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030983314
    Series Statement: Stem Cell Biology and Regenerative Medicine, 72
    DDC: 610.72
    Language: English
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