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  • thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
  • Springer Nature  (15)
  • Wiley-Blackwell
  • 2020-2024  (16)
  • 1940-1944
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Keywords
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Language
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  • 2020-2024  (16)
  • 1940-1944
Year
  • 1
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    Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft (2024)
    Springer Nature | Springer Berlin Heidelberg
    Details
    Publication Date: 2024-04-07
    Description: Wenn Sie sich für den Stand der Dinge auf dem Gebiet der Gen- und Zelltherapie interessieren, bietet Ihnen diese Open-Access-Publikation einen umfassenden und hochaktuellen Überblick. Wissenschaftler und Experten behandeln Fragen wie: Haben CAR-T-Zellen etwas mit Autos zu tun, wie funktionieren Genfähren, können uns Stammzellen bei Therapien helfen, was sind Organoide und warum dauert es oft so lange, bis neuartige Behandlungskonzepte in die Klinik kommen? Kann man Gene wie Bücher editieren, wie gefährlich ist das eigentlich und wer kontrolliert sowas, muss Gentherapie so teuer sein und ist sichergestellt, dass alle Patienten die Therapie bekommen, die sie benötigen?
    Keywords: Genome Editing ; Keimbahnmodifikation ; Genetisches Enhancement ; Vektoren ; Immuntherapie ; Stammzelltransplantation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: German
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  • 2
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    Chapter PRINCIPLES OF PI3K BIOLOGY AND ITS ROLE IN LYMPHOMA (2023)
    Wiley-Blackwell
    Details
    Publication Date: 2024-04-07
    Description: PI3K biology; lymphoma; cancer
    Keywords: PI3K biology; lymphoma; cancer ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 3
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    Sexual Reproduction in Animals and Plants (2021)
    Springer Nature
    Details
    Publication Date: 2024-04-06
    Description: Developmental Biology; Plant Sciences; Cell Biology
    Keywords: Developmental Biology ; Plant Sciences ; Cell Biology ; thema EDItEUR::K Economics, Finance, Business and Management::KN Industry and industrial studies::KND Manufacturing industries ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering
    Language: English
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  • 4
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    Bioimage Data Analysis Workflows ‒ Advanced Components and Methods (2022)
    Springer Nature | Springer
    Details
    Publication Date: 2024-04-05
    Description: This open access textbook aims at providing detailed explanations on how to design and construct image analysis workflows to successfully conduct bioimage analysis. Addressing the main challenges in image data analysis, where acquisition by powerful imaging devices results in very large amounts of collected image data, the book discusses techniques relying on batch and GPU programming, as well as on powerful deep learning-based algorithms. In addition, downstream data processing techniques are introduced, such as Python libraries for data organization, plotting, and visualizations. Finally, by studying the way individual unique ideas are implemented in the workflows, readers are carefully guided through how the parameters driving biological systems are revealed by analyzing image data. These studies include segmentation of plant tissue epidermis, analysis of the spatial pattern of the eye development in fruit flies, and the analysis of collective cell migration dynamics. The presented content extends the Bioimage Data Analysis Workflows textbook (Miura, Sladoje, 2020), published in this same series, with new contributions and advanced material, while preserving the well-appreciated pedagogical approach adopted and promoted during the training schools for bioimage analysis organized within NEUBIAS – the Network of European Bioimage Analysts. This textbook is intended for advanced students in various fields of the life sciences and biomedicine, as well as staff scientists and faculty members who conduct regular quantitative analyses of microscopy images.
    Keywords: Analyzing Image Data in Biology ; Building a Bioimage Analysis Workflow ; Computational Analysis ; Chosing the Correct Components for Given Biological Questions ; Data Handling and Plotting ; Deep Learning ; Fast Computation ; GPU-Acceleration ; Handling Biological data ; Machine Learning ; Phyton ; Processing Language ; Understanding Bioimage Analysis Software ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology ; thema EDItEUR::P Mathematics and Science::PN Chemistry::PNF Analytical chemistry ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 5
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    Organization in Biology (2023)
    Springer Nature | Springer International Publishing
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    Publication Date: 2024-04-05
    Description: This open access book assesses the prospects of (re)adopting organization as a pivotal concept in biology. It shows how organization can nourish biological thinking and practice, by reconnecting with the idea of biology as the science of organized systems. The book provides a comprehensive state-of-the-art picture of the characterizations and uses of the concept of organization in both biological science and philosophy of biology. It also deals with a variety of themes – including evolution, organogenesis, heredity, cognition and ecology – with respect to which the concept of organization can guide the elaboration of original models and new experimental protocols. It will be of interest to biologists and scholars working in philosophy of science alike.
    Keywords: Biological Modeling ; Biological Organization ; Organicism ; Philosophy of Biology ; Reductionism and antireductionism ; Theoretical Biology ; thema EDItEUR::Q Philosophy and Religion::QD Philosophy ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 6
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    The Gene Ontology Handbook (2021)
    Springer Nature
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    Publication Date: 2024-04-05
    Description: bioinformatics; biotechnology
    Keywords: bioinformatics ; biotechnology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 7
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    Chapter Developing a Model to Simulate the Effect of Hypothermia on Cerebral Blood Flow and Metabolism (2022)
    Springer Nature | Oxygen Transport to Tissue XLI
    Details
    Publication Date: 2024-04-05
    Description: Hypoxic ischemic encephalopathy (HIE) is a significant cause of death and neurological disability in newborns. Therapeutic hypothermia at 33.5 °C is one of the most common treatments in HIE and generally improves outcome; however 45–55% of injuries still result in death or severe neurodevelopmental disability. We have developed a systems biology model of cerebral oxygen transport and metabolism to model the impact of hypothermia on the piglet brain (the neonatal preclinical animal model) tissue physiology. This computational model is an extension of the BrainSignals model of the adult brain. The model predicts that during hypothermia there is a 5.1% decrease in cerebral metabolism, 1.1% decrease in blood flow and 2.3% increase in cerebral tissue oxygenation saturation. The model can be used to simulate effects of hypothermia on the brain and to help interpret bedside recordings.
    Keywords: Broadband NIRS, Hypothermia, Systems biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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  • 8
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    Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft (2024)
    Springer Nature | Springer Berlin Heidelberg
    Details
    Publication Date: 2024-04-05
    Description: Wenn Sie sich für den Stand der Dinge auf dem Gebiet der Gen- und Zelltherapie interessieren, bietet Ihnen diese Open-Access-Publikation einen umfassenden und hochaktuellen Überblick. Wissenschaftler und Experten behandeln Fragen wie: Haben CAR-T-Zellen etwas mit Autos zu tun, wie funktionieren Genfähren, können uns Stammzellen bei Therapien helfen, was sind Organoide und warum dauert es oft so lange, bis neuartige Behandlungskonzepte in die Klinik kommen? Kann man Gene wie Bücher editieren, wie gefährlich ist das eigentlich und wer kontrolliert sowas, muss Gentherapie so teuer sein und ist sichergestellt, dass alle Patienten die Therapie bekommen, die sie benötigen?
    Keywords: Genome Editing ; Keimbahnmodifikation ; Genetisches Enhancement ; Vektoren ; Immuntherapie ; Stammzelltransplantation ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: German
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  • 9
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    The Wheat Genome (2024)
    Springer Nature | Springer International Publishing
    Details
    Publication Date: 2024-04-05
    Description: This open access book provides the first comprehensive coverage of the wheat genome sequence since the publication of the draft and reference sequences for bread wheat and durum wheat. It presents an overview and all aspects of the gold standard sequence of the bread wheat genome, IWGSC RefSeq v1.0 and its subsequent improvements through 2022 (IWGSC RefSeq v2.1), as well as the sequencing of multiple elite wheat varieties, durum wheat, and ancient wheat. The book provides a broad and extensive review of the resources, tools, and methodologies available for exploiting the wheat genome sequence for crop improvement and studying fundamental questions related to the structure, function, and evolution of the wheat genome. Wheat (Tritcum aestivum L.) is the most widely grown crop in the world, contributing approximately 20 percent of total calories and more protein in human diets than any other single source. This book is useful to students, teachers, and scientists in academia and industry interested in gaining an understanding of the wheat genome and its application as well as plant scientists generally interested in polyploid plant species.
    Keywords: International Wheat Genome Sequencing Consortium ; polyploidy ; wheat genome sequence ; structural genomics ; functional genomics ; wheat evolution ; wheat improvement ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PST Botany and plant sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnology ; thema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TV Agriculture and farming::TVB Agricultural science ; thema EDItEUR::U Computing and Information Technology::UY Computer science ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistry
    Language: English
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  • 10
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    Trypanosomatids (2021)
    Springer Nature
    Details
    Publication Date: 2024-04-05
    Description: This volume explores the latest methods used by researchers to study different trypanosomatid parasites. These methods cover numerous disciplines, from organismal biology to molecular mechanism. The chapters in this book cover topics such as high-throughput sequencing; next-generation analysis of trypanosomatid genome stability and instability; DNA repair in cell extracts; ribosome profiling; and the use of CRISPR/Cas9 technology for gene editing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Trypanosomatids: Methods and Protocols is a valuable resource for any researcher working with trypanosomatids and trypanosomatid-borne diseases.
    Keywords: infectious disease; trypanosomatid parasites; biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences
    Language: English
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