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  • Pregnancy  (19)
  • American Association for the Advancement of Science (AAAS)  (19)
  • 2020-2024
  • 1975-1979  (19)
  • 1978  (19)
  • 1977
Collection
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (19)
  • Springer  (4)
Years
  • 2020-2024
  • 1975-1979  (19)
Year
  • 1978  (19)
  • 1977
  • 1979  (26)
  • 1
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    Restriction enzymes: prenatal diagnosis of genetic disease (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marx, J L -- New York, N.Y. -- Science. 1978 Dec 8;202(4372):1068-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715458" target="_blank"〉PubMed〈/a〉
    Keywords: Anemia, Sickle Cell/*diagnosis/genetics ; DNA Restriction Enzymes/*metabolism ; Female ; Globins/genetics ; Humans ; Pregnancy ; Prenatal Diagnosis/*methods ; Thalassemia/*diagnosis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Synchronies in mental development: an epigenetic perspective (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-12-01
    Description: Early mental development is analyzed from an evolutionary viewpoint and related to the dynamic interplay of genetic programming, maturational status, and environmental influence. Data are reported from a large sample of twins and siblings who have been tested longitudinally from 3 months to 6 years of age. Monozygotic twins became increasingly concordant with age and also paralleled each other for the spurts and lags in development. Dizygotic twins became less concordant with age and eventually matched their singleton siblings as closely as one another. The overall results suggested that the course of mental development is guided by the intrinsic scheduling of the genetic program acting in concert with maturational status and environmental influence.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wilson, R S -- New York, N.Y. -- Science. 1978 Dec 1;202(4371):939-48.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/568822" target="_blank"〉PubMed〈/a〉
    Keywords: Behavior/physiology ; *Biological Evolution ; Child ; Child, Preschool ; Environment ; Female ; Genes ; *Growth ; Humans ; Infant ; Infant, Newborn ; Infant, Premature ; Intelligence ; Mental Processes/*physiology ; Pregnancy ; *Twins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    S-adenosylhomocysteine hydrolase is an adenosine-binding protein: a target for adenosine toxicity (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-11-17
    Description: When adenosine deaminase activity is inhibited, low concentrations of adenosine are toxic to human lymphoblast mutants that are unable to convert adenosine to intracellular nucleotides. In order to identify the mediator of this cytotoxicity, we searched for a cytoplasmic protein capable of binding adenosine with high affinity. Such a protein was identified in extracts of human lymphoblasts and placenta as the enzyme S-adenosylhomocysteine hydrolase.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hershfield, M S -- Krodich, N M -- New York, N.Y. -- Science. 1978 Nov 17;202(4369):757-60.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/715439" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine/*metabolism ; Adenosine Deaminase/*deficiency ; Carrier Proteins/*metabolism ; Female ; Humans ; Hydrolases/*metabolism ; Kinetics ; Lymphocytes/metabolism ; Nucleoside Deaminases/*deficiency ; Placenta/metabolism ; Pregnancy ; S-Adenosylhomocysteine/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    Behavioral teratology: birth defects of the mind (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-11-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G B -- New York, N.Y. -- Science. 1978 Nov 17;202(4369):732-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/568821" target="_blank"〉PubMed〈/a〉
    Keywords: Anesthesia, Obstetrical/adverse effects ; Behavior/*drug effects ; Female ; Gonadal Steroid Hormones/adverse effects ; Humans ; Infant ; Infant, Newborn ; Infant, Newborn, Diseases/chemically induced ; Male ; Mental Disorders/*chemically induced ; Narcotics ; Pregnancy ; Semen/metabolism ; Spermatozoa/drug effects ; Substance Withdrawal Syndrome/etiology ; *Teratogens/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Prolactin synthesis by human chorion-decidual tissue: a possible source of prolactin in the amniotic fluid (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-10-20
    Description: Explants of human chorion-decidual tissue obtained at delivery from normal, full-term pregnancies synthesize and secrete prolactin. This hormone is indistinguishable from pituitary prolactin by chromatographic, electrophoretic, immunologic, and receptor assay techniques. These results suggest that chorion-decidua may be the source of the large quantities of prolactin in amniotic fluid.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Golander, A -- Hurley, T -- Barrett, J -- Hizi, A -- Handwerger, S -- New York, N.Y. -- Science. 1978 Oct 20;202(4365):311-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/694535" target="_blank"〉PubMed〈/a〉
    Keywords: Amnion/metabolism ; Amniotic Fluid/*metabolism ; Chorion/*metabolism ; Decidua/*metabolism ; Female ; Humans ; In Vitro Techniques ; Pregnancy ; Prolactin/*biosynthesis ; Trophoblasts/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Primate infant's effects on mother's future reproduction (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-09-15
    Description: Female savanna baboons (Papio cynocephalus) had a longer postpartum amenorrhea and thereafter cycled longer before conceiving if their previous infant survived than if that infant died. Among mothers of surviving infants, differences in maternal care produced differences in age of weaning and age of independence but did not result in differences in interbirth intervals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Altmann, J -- Altmann, S A -- Hausfater, G -- New York, N.Y. -- Science. 1978 Sep 15;201(4360):1028-30.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/98844" target="_blank"〉PubMed〈/a〉
    Keywords: Amenorrhea ; Animals ; Female ; Haplorhini ; Maternal Behavior ; Papio/*physiology ; *Postpartum Period ; Pregnancy ; *Reproduction ; Time Factors ; Weaning
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Hepatitis B virus and sex ratio of offspring (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-08-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Drew, J S -- London, W T -- Lustbader, E D -- Hesser, J E -- Blumberg, B S -- New York, N.Y. -- Science. 1978 Aug 25;201(4357):687-92.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/566954" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Birth Order ; Cross Reactions ; Female ; Fetal Death ; Graft Survival ; Hepatitis B/immunology/*physiopathology/transmission ; Hepatitis B Surface Antigens/analysis ; Humans ; Male ; Parity ; Pregnancy ; Sex Factors ; *Sex Ratio
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    Enhanced dexamethasone resistance in cystic fibrosis cells: potential use for heterozygote detection and prenatal diagnosis (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-07-14
    Description: Cultured skin fibroblasts from patients with cystic fibrosis (CF) are more resistant to dexamethasone toxicity than are normal cells. We now report that, when fibroblasts cultured from obligate CF heterozygotes are exposed to dexamethasone, they have an intermediate survival compared to normal and homozygous CF cells. When dexamethasone survival was tested on cells from four patients undergoing amniocentesis, cells from a woman at risk of producing a child with CF showed significant dexamethasone resistance, similar to that of fibroblasts derived from lnown CF homozygotes; the other amniotic cell specimens showed dexamethasone sensitivity similar to that of normal skin fibroblasts. These data suggest that the dexamethasone resistance previously observed in skin fibroblasts may also be useful in the prenatal diagnosis of CF.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Breslow, J L -- Epstein, J -- Fontaine, J H -- Forbes, G B -- New York, N.Y. -- Science. 1978 Jul 14;201(4351):180-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663650" target="_blank"〉PubMed〈/a〉
    Keywords: Amniotic Fluid/cytology ; Cell Survival/drug effects ; Cystic Fibrosis/diagnosis/genetics/*physiopathology ; Dexamethasone/*toxicity ; Drug Resistance ; Female ; Heterozygote ; Homozygote ; Humans ; Pregnancy ; Prenatal Diagnosis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    6-Mercaptopurine treatment of pregnant mice: effects on second and third generations (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-07-07
    Description: The immunosuppressive drug 6-mercaptopurine is embryotoxic in mice. Of the surviving female offspring of mice treated with low doses of 6-mercaptopurine during pregnancy, despite normal body weight and general appearance, many were either sterile or, if they became pregnant, had smaller litters and more dead fetuses as compared to offspring of mothers that had not received the drug.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Reimers, T J -- Sluss, P M -- New York, N.Y. -- Science. 1978 Jul 7;201(4350):65-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/663638" target="_blank"〉PubMed〈/a〉
    Keywords: 6-Mercaptopurine/*pharmacology ; Animals ; Dose-Response Relationship, Drug ; Female ; Fetal Death/*chemically induced ; Fetus/drug effects ; Germ Cells/*drug effects ; Infertility, Female/*chemically induced ; Litter Size/drug effects ; Mice ; Ovary/cytology/drug effects/embryology ; Pregnancy ; Pregnancy, Animal/*drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Postpartum amenorrhea: how is it affected by maternal nutritional status? (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-06-09
    Description: The average length of postpartum amenorrhea reported by breast-feeding women in rural Bangladesh in 1975 was 18 to 20 months. Its duration was found to be only slightly related to maternal nutritional status. There was no evidence of a threshold of weight for height necessary for the resumption of menses postpartum. Factors related to the duration of postpartum amenorrhea were maternal age, socioeconomic status, and supplemental feeding of the infant.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Huffman, S L -- Chowdhury, A K -- Mosley, W H -- New York, N.Y. -- Science. 1978 Jun 9;200(4346):1155-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/653359" target="_blank"〉PubMed〈/a〉
    Keywords: Amenorrhea/*etiology ; Body Water/metabolism ; Body Weight ; Female ; Humans ; Infant Nutritional Physiological Phenomena ; *Lactation ; Maternal Age ; Menstruation ; Nutrition Disorders/metabolism ; *Nutritional Physiological Phenomena ; *Postpartum Period ; Pregnancy ; Socioeconomic Factors ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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