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  • Articles  (489)
  • United States  (389)
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  • American Association for the Advancement of Science (AAAS)  (489)
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  • 2020-2023
  • 2000-2004  (311)
  • 1995-1999  (178)
  • 2002  (311)
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  • Articles  (489)
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  • 2020-2023
  • 2000-2004  (311)
  • 1995-1999  (178)
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  • 1
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    The paucity of grants among young scientists (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉McColl, Damian J -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2328-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12498167" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Career Mobility ; *Education, Graduate ; Financing, Government ; Humans ; *National Institutes of Health (U.S.) ; *Research Personnel ; *Research Support as Topic ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    The paucity of grants among young scientists (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Campbell, Peter -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2328-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12498168" target="_blank"〉PubMed〈/a〉
    Keywords: Biological Science Disciplines/*education ; *Education, Graduate ; Great Britain ; Time Factors ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    The paucity of grants among young scientists (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-25
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Djerassi, Carl -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2328-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12498165" target="_blank"〉PubMed〈/a〉
    Keywords: Financing, Government ; Humans ; *National Institutes of Health (U.S.) ; *Research Personnel ; *Research Support as Topic ; United States ; Universities
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    A distinct signaling pathway used by the IgG-containing B cell antigen receptor (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-21
    Description: The immunoglobulin G (IgG)-containing B lymphocyte antigen receptor (IgG-BCR) transmits a signal distinct from that of IgM-BCR or IgD-BCR, although all three use the same signal-transducing component, Igalpha/Igbeta. Here we demonstrate that the inhibitory coreceptor CD22 down-modulates signaling through IgM-BCR and IgD-BCR, but not that through IgG-BCR, because of the IgG cytoplasmic tail, which prevents CD22 phosphorylation. These results suggest that the cytoplasmic tail of IgG specifically enhances IgG-BCR signaling by preventing CD22-mediated signal inhibition. Enhanced signaling through IgG-BCR may be involved in efficient IgG production, which is crucial for immunity to pathogens.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wakabayashi, Chisato -- Adachi, Takahiro -- Wienands, Jurgen -- Tsubata, Takeshi -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2392-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Immunology, Medical Research Institute, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12493916" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigens, CD/metabolism ; Antigens, Differentiation, B-Lymphocyte/metabolism ; B-Lymphocytes/immunology/metabolism ; Calcium/metabolism ; Calcium Signaling ; *Cell Adhesion Molecules ; Cells, Cultured ; Immunoglobulin D/immunology/metabolism ; Immunoglobulin G/chemistry/immunology/*metabolism ; Intracellular Signaling Peptides and Proteins ; Lectins/metabolism ; Mice ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3 ; Mitogen-Activated Protein Kinases/metabolism ; Phosphorylation ; Protein Tyrosine Phosphatase, Non-Receptor Type 6 ; Protein Tyrosine Phosphatases/metabolism ; Receptors, Antigen, B-Cell/chemistry/immunology/*metabolism ; Sialic Acid Binding Ig-like Lectin 2 ; *Signal Transduction ; Transfection ; Tumor Cells, Cultured
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Science and security. Academy asks to ease visas for scholars (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malakoff, David -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2305-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12493883" target="_blank"〉PubMed〈/a〉
    Keywords: Education, Graduate ; *Emigration and Immigration ; *National Academy of Sciences (U.S.) ; *Research Personnel ; *Security Measures ; Students ; *Travel ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Biological agents. New U.S. rules set the stage for tighter security, oversight (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Malakoff, David -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2304.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12493881" target="_blank"〉PubMed〈/a〉
    Keywords: Advisory Committees ; Bioterrorism/*legislation & jurisprudence/prevention & control ; Genetic Engineering ; Guidelines as Topic ; Research/*legislation & jurisprudence ; *Security Measures ; United States ; United States Dept. of Health and Human Services
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    2004 budget. No holiday cheer for NIH, NSF (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mervis, Jeffrey -- Kaiser, Jocelyn -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2308-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12493885" target="_blank"〉PubMed〈/a〉
    Keywords: *Budgets ; National Institutes of Health (U.S.)/*economics ; *Science ; United States ; *United States Government Agencies
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    California budget. Latest cuts send universities reeling (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lawler, Andrew -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2305.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12493882" target="_blank"〉PubMed〈/a〉
    Keywords: Academies and Institutes/economics ; Animals ; Biological Specimen Banks ; *Budgets ; California ; Ecosystem ; Oceanography ; Research/*economics ; Seawater ; Universities/*economics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    Public health. Strengthening the FDA (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Friedman, Michael A -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2332.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Pharmacia Corporation, Peapack, NJ 07977, USA. Michael.a.friedman@pharmacia.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12493898" target="_blank"〉PubMed〈/a〉
    Keywords: Budgets ; United States ; United States Dept. of Health and Human Services ; *United States Food and Drug Administration/economics/organization & ; administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Breakthrough of the year. Bioterrorism: the calm after the storm (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-12-21
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Enserink, Martin -- New York, N.Y. -- Science. 2002 Dec 20;298(5602):2300.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12493879" target="_blank"〉PubMed〈/a〉
    Keywords: Access to Information ; Anthrax ; Biological Warfare ; *Bioterrorism/prevention & control ; Humans ; Security Measures ; Smallpox ; Smallpox Vaccine ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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