ALBERT

Note: Introduction: heritage and climate change: the future is not the past , Narratives of change on the Jurassic Coast World Heritage Site , Heritage and climate change: a fatal affair , Climate and cultural heritage: an experiment with the weather memory bank , Diverse epistemic traditions in transformative climate change research and adaptation: heritage and legacy , "We now have a name for some of the big changes happening on our bubu [country]": the role of indigenous knowledge for the management of cultural landscapes in a changing climate: a case study of the Kuku Nyungkal people from the Queensland Wet Tropics, Australia , Climate change and the changing nature of conservation , Historical chestnut cultures, climate and rural landscapes in the Apennines , Part II. Creative responses to heritage and climate change relations: processes, policies and possibilities ; Heritage and climate change: organizational conflicts and conundrums , Heritage development and community resilience: insights for the era of climate change , Strategies for coping with the wicked problem of climate change: a natural heritage perspective , Buffer mechanisms for managing diversity and world heritage in the Cape Floral Region (South Africa) , "From dust to dust": earth buildings, process and change , Relationships between climate change and built heritage: the case of dense urban cities in Hong Kong and China , Taking the middle path to the coast: how community collaboration can help save threatened sites , Conclusion: valuing the ever-changing past

Note: Contents Part I Introduction 1 Cardiac Development and Animal Models of Congenital Heart Defects / Robert G. Kelly 2 Normal Cardiac Anatomy and Clinical Evaluation / David J. Driscoll Part II Development of the Heart and Its Vessels 3 First and Second Heart Field / Margaret Buckingham 4 Neural Crest / Bijoy Thattaliyath and Mary Hutson 5 Inflow Tract Development / Andy Wessels 6 Epicardium and Coronary Arteries / José C. Martín-Robles and José M. Pérez-Pomares 7 Establishment of Cardiac Laterality / George C. Gabriel and Cecilia W. Lo 8 Cardiac Conduction System / Rajiv Mohan and Vincent M. Christoffels 9 Hemodynamics During Development and Postnatal Life / David Sedmera 10 Evolutionary Aspects of Cardiac Development / Bjarke Jensen and Antoon F.M. Moorman Part III Central Molecular Pathways 11 Inter- and Intracellular Signaling Pathways / Jörg Heineke 12 Cardiac Transcription Factors and Regulatory Networks / Marcel Grunert, Cornelia Dorn, and Silke Rickert-Sperling 13 Post-transcriptional Regulation by Proteins and Non-coding RNAs / Amelia E. Aranega and Diego Franco 14 Post-translational Modification / Jun Wang and Robert J. Schwartz 15 Epigenetics / Rajan Jain, Mudit Gupta, and Jonathan A. Epstein 16 Environmental Signals / George A. Porter Jr. 17 The Contractile Apparatus of the Heart / Ingo Morano 18 Technologies to Study Genetics and Molecular Pathways / Cornelia Dorn, Marcel Grunert, Ana Dopazo, Fátima Sánchez-Cabo, Alberto Gatto, Jésus Vázquez, Silke Rickert-Sperling, and Enrique Lara-Pezzi Part IV Atrial Septal Defect 19 Clinical Presentation and Therapy of Atrial Septal Defect / David J. Driscoll 20 Human Genetics of Atrial Septal Defect / Rabia Khan and Patrick Y. Jay 21 Molecular Pathways and Animal Models of Atrial Septal Defect / Patrick Y. Jay, Karl R. Degenhardt, and Robert H. Anderson Part V Ventricular Septal Defect 22 Clinical Presentation and Therapy of Ventricular Septal Defect / David J. Driscoll 23 Human Genetics of Ventricular Septal Defect / Katherina Bellmann, Andreas Perrot, and Silke Rickert-Sperling 24 Molecular Pathways and Animal Models of Ventricular Septal Defect / Lucile Houyel Part VI Atrioventricular Septal Defect 25 Clinical Presentation and Therapy of Atrioventricular Septal Defect / David J. Driscoll 26 Human Genetics of Atrioventricular Septal Defect / Cheryl L. Maslen 27 Molecular Pathways and Animal Models of Atrioventricular Septal Defect / Andy Wessels Part VII Total Anomalous Pulmonary Venous Return 28 Clinical Presentation and Therapy of Total Anomalous Pulmonary Venous Return / David J. Driscoll 29 Human Genetics of Total Anomalous Pulmonary Venous Return / Robert E. Poelmann, Monique R.M. Jongbloed, Marco C. DeRuiter, and Adriana C. Gittenberger-de Groot 30 Molecular Pathways and Animal Models of Total Anomalous Pulmonary Venous Return / Robert E. Poelmann, Adriana C. Gittenberger-de Groot, Monique R.M. Jongbloed, and Marco C. DeRuiter Part VIII Tetralogy of Fallot and Double Outlet Right Ventricle 31 Clinical Presentation and Therapy of Tetralogy of Fallot and Double Outlet Right Ventricle / David J. Driscoll 32 Human Genetics of Tetralogy of Fallot and Double Outlet Right Ventricle / Cornelia Dorn, Andreas Perrot, and Silke Rickert-Sperling 33 Molecular Pathways and Animal Models of Tetralogy of Fallot and Double Outlet Right Ventricle / Robert G. Kelly Part IX d-Transposition of the Great Arteries 34 Clinical Presentation and Therapy of d-Transposition of the Great Arteries / David J. Driscoll 35 Human Genetics of d-Transposition of the Great Arteries / Patrice Bouvagnet and Anne Moreau de Bellaing 36 Molecular Pathways and Animal Models of d-Transposition of the Great Arteries / Amy-Leigh Johnson and Simon D. Bamforth Part X Defects of Situs 37 Clinical Presentation and Therapy of Defects of Situs / David J. Driscoll 38 Human Genetics of Defects of Situs / Andreas Perrot and Silke Rickert-Sperling 39 Molecular Pathways and Animal Models of Defects of Situs / Nikolai T. Klena, George C. Gabriel, and Cecilia W. Lo Part XI Semilunar Valve and Aortic Arch Anomalies 40 Clinical Presentation and Therapy of Semilunar Valve and Aortic Arch Anomalies / David J. Driscoll 41 Human Genetics of Semilunar Valve and Aortic Arch Anomalies / Matina Prapa and Siew Yen Ho 42 Molecular Pathways and Animal Models of Semilunar Valve and Aortic Arch Anomalies / Amy-Leigh Johnson and Simon D. Bamforth Part XII Coronary Artery Anomalies 43 Clinical Presentation and Therapy of Coronary Artery Anomalies / David J. Driscoll 44 Human Genetics of Coronary Artery Anomalies / Beatriz Picazo and José M. Pérez-Pomares 45 Molecular Pathways and Animal Models of Coronary Artery Anomalies / Juan A. Guadix and José M. Pérez-Pomares Part XIII Truncus Arteriosus 46 Clinical Presentation and Therapy of Truncus Arteriosus / David J. Driscoll 47 Human Genetics of Truncus Arteriosus / Hiroyuki Yamagishi 48 Molecular Pathways and Animal Models of Truncus Arteriosus / Amy-Leigh Johnson and Simon D. Bamforth Part XIV Tricuspid Atresia and Univentricular Heart 49 Clinical Presentation and Therapy of Tricuspid Atresia and Univentricular Heart / David J. Driscoll 50 Human Genetics of Tricuspid Atresia and Univentricular Heart / Abdul-Karim Sleiman, Liane Sadder, and George Nemer 51 Molecular Pathways and Animal Models of Tricuspid Atresia and Univentricular Heart / Kamel Shibbani and George Nemer Part XV Ebstein Anomaly 52 Clinical Presentation and Therapy of Ebstein Anomaly / David J. Driscoll 53 Human Genetics of Ebstein Anomaly / Gregor U. Andelfinger 54 Molecular Pathways and Animal Models of Ebstein Anomaly / Gregor U. Andelfinger Part XVI Hypoplastic Left Heart Syndrome 55 Clinical Presentation and Therapy of Hypoplastic Left Heart Syndrome / David J. Driscoll 56 Human Genetics of Hypoplastic Left Heart Syndrome / Woodrow D. Benson 57 Molecular Pathways and Animal Models of Hypoplastic Left Heart Syndrome / Florian Wünnemann and Gregor U. Andelfinger Part XVII Cardiomyopathies 58 Clinical Presentation and Therapy of Cardiomyopathies / David J. Driscoll 59 Human Genetics of Cardiomyopathies / Alexa M.C. Vermeer, Arthur A.M. Wilde, and Imke Christiaans 60 Molecular Pathways and Animal Models of Cardiomyopathies / Enkhsaikhan Purevjav