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  • 1
    Online-Ressource
    Online-Ressource
    The Renin Angiotensin System in Cardiovascular Disease (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Cardiovascular system. ; Physiology. ; Cardiology. ; Clinical biochemistry. ; Biomedical Research. ; Cardiovascular Physiology. ; Cardiology. ; Medical Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure.
    Kurzfassung: This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.
    Materialart: Online-Ressource
    Seiten: XVIII, 452 p. 71 illus., 54 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031149528
    Serie: Advances in Biochemistry in Health and Disease, 24
    URL: https://doi.org/10.1007/978-3-031-14952-8
    DOI: 10.1007/978-3-031-14952-8
    DDC: 610.72
    Sprache: Englisch
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  • 2
    Online-Ressource
    Online-Ressource
    Genome Editing in Cardiovascular and Metabolic Diseases (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Metabolism Disorders. ; Genetics. ; Cardiovascular system. ; Physiology. ; Biomedical Research. ; Metabolic Disease. ; Genetics and Genomics. ; Cardiovascular Physiology.
    Beschreibung / Inhaltsverzeichnis: An overview of genome editing in cardiovascular and metabolic diseases -- Bioinformatics research methodology of genome editing in cardiovascular and metabolic diseases -- Online databases of genome editing in cardiovascular and metabolic diseases -- Application of systems biology for genome editing involved in regulating of cardiovascular and metabolic diseases -- Bioinformatics for reducing off-targets in cardiovascular and metabolic diseases -- Genome editing and cardiac regeneration -- Genome editing and myocardial development -- Genome editing and heart failure -- Genome editing and pathological cardiac hypertrophy -- Genome editing and cardiac remodeling -- Genome editing and diabetic cardiomyopathy -- Genome editing and cardiac arrhythmias -- Genome editing and atrial fibrillation -- Genome editing and muscle atrophy -- Genome editing and obesity -- Genome editing and fatty liver -- Genome editing and diabetes -- Genome editing and gout -- Genome editing and protein energy malnutrition -- Genome therapy and cardiovascular diseases -- Therapeutics in metabolic diseases -- Gene editing and human iPSCs in cardiovascular and editing diseases -- Prospective advances in genome editing investigation.
    Kurzfassung: This book provides the latest research progress on genome editing in cardiovascular and metabolic diseases and includes bioinformatics research methodology of genome editing. Genome editing is a genetic engineering technique precisely modified specific target genes of organism genome, which has been applied to basic theoretical research and production applications from plants and animals to gene therapy of human beings. Cardiovascular and metabolic diseases have become major factors affecting human health worldwide. This book contains information about bioinformatics, genome editing in cardiovascular diseases, genome editing in metabolic diseases and therapeutic effects. It will be useful for biologist, cardiologist, cardiovascular surgeons, endocrinologist, internists, nurses, undergraduate and graduate students in medicine and cell biology and others interested in cardiovascular and metabolic medicine.
    Materialart: Online-Ressource
    Seiten: XII, 339 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811956423
    Serie: Advances in Experimental Medicine and Biology, 1396
    URL: https://doi.org/10.1007/978-981-19-5642-3
    DOI: 10.1007/978-981-19-5642-3
    DDC: 610.72
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Online-Ressource
    Online-Ressource
    Biomedical Visualisation : Volume 14 ‒ COVID-19 Technology and Visualisation Adaptations for Biomedical Teaching (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical education. ; Anatomy. ; Virtual reality. ; Augmented reality. ; Biomedical Research. ; Medical Education. ; Anatomy. ; Virtual and Augmented Reality.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Pandemic-Era Digital Education: Insights from an Undergraduate Medical Programme -- Chapter 2. Use of Lt Systems in Large Class Lab Delivery -- Chapter 3. COVID-19 Adaptations for Biomedical Teaching and Assessment Within the Undergraduate Dental Curriculum -- Chapter 4. One Size Does Not Fit All in Remote Anatomy Teaching -- Chapter 5. From Lecture Halls to Zoom Links: How Can Educational Theory Help Us to Deliver Effective and Engaging Teaching in an Online Environment? -- Chapter 6. Collaborative, Two-Directional Live Streaming to Deliver Hands-on Dissection Experience during the COVID-19 Lockdown -- Chapter 7. Livestreaming Can Augment the Observation of Veterinary Post-mortem Examinations -- Chapter 8. Virtual Reality for Anatomy and Surgical Teaching -- Chapter 9. Can Synchronous Online Near-Peer Teaching Offer the Same Benefits as the Face-to-Face Version When Used in Clinical Neuroanatomy Education? -- Chapter 10. COVID-19 Adaptations with Virtual Microscopy -- Chapter 11. The Challenges of Visualisation During Delivery and Assessment of Clinical Teaching Under COVID-19: A Reflective Account of Problem Solving -- Chapter 12. Not for Room 101.
    Kurzfassung: This book focuses on the challenges to biomedical education posed by the lockdowns and restrictions to on campus teaching brought about by the COVID-19 pandemic and highlights the tools and digital visualization technologies that have been successfully developed and used for remote teaching. Biomedical education for science, medical, dental and allied health professionals relies on teaching visual and tactile knowledge using practice-based approaches. This has been delivered for decades via on-campus lectures, workshops and laboratories, teaching practical skills as well as fundamental knowledge and understanding. However, the arrival of the COVID-19 pandemic meant that education across the globe had to pivot very quickly to be able to deliver these skills and knowledge in a predominantly online environment. This brought with it many challenges, as Higher Education staff, had to adapt to deliver these visual subjects remotely. This book addresses the challenges and solutions faced by Higher Education staff in teaching visual content in distance education. Chapters include literature reviews, original research, and pedagogical reflections for a wide range of biomedical subjects, degrees such as medicine, dentistry and veterinary sciences with examples from undergraduate and postgraduate settings. The goal of the book is to provide a compendium of expertise based on evidence gathered during the COVID-19 pandemic, as well as reflections on the challenges and lessons learned from this dramatic shift in teaching. It also presents new examples of best practices that have emerged from this experience to ensure that they are not lost as we return to on-campus learning in a new era of biomedical teaching. This book will be of interest to anyone looking for a helpful reference point when designing online or blended teaching for visual practice-based subjects.
    Materialart: Online-Ressource
    Seiten: X, 228 p. 56 illus., 52 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031171352
    Serie: Advances in Experimental Medicine and Biology, 1397
    URL: https://doi.org/10.1007/978-3-031-17135-2
    DOI: 10.1007/978-3-031-17135-2
    DDC: 610.72
    Sprache: Englisch
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  • 4
    Online-Ressource
    Online-Ressource
    Biological Effects of Static Magnetic Fields (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Cytology. ; Biomedical Research. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Magnetic Field Parameters and Biological Sample Differences that Lead to Differential Bioeffects -- Chapter 2. Static Magnetic Field Direction-induced Differential Biological Effects -- Chapter 3. Magnetic Properties of Biological Samples -- Chapter 4. Molecular Mechanisms for Electromagnetic Field Biosensing -- Chapter 5. Controlling Cell Membrane Potential with Static Non-uniform Magnetic Fields -- Chapter 6. Impact of Static Magnetic Fields on Cells -- Chapter 7. Impact of Static Magnetic Fields on Microorganisms, Plants and Animals -- Chapter 8. Static Magnetic Fields on Human Bodies -- Chapter 9. Potential Applications of Static Magnetic Fields in Cancer Treatment -- Chapter 10. Effects of Static Magnetic Fields on Diabetes and Its Complications -- Chapter 11. Impacts of Static Magnetic Field on Bone Health -- Chapter 12. Effects of Static Magnetic Fields on the Immune System -- Chapter 13. Biological Effects of Static Magnetic Fields on the Nervous System -- Chapter 14. The Biological Effects of Long-term Static Magnetic Field Exposure -- Chapter 15. Prospects, Pitfalls, and Opportunities for Human Static Magnetic Field Therapy.
    Kurzfassung: The book summarizes the emerging topic about the effects of SMF on biological samples ranging from single molecules, subcellular compartments, and cells to whole organisms. It also discusses the potential application of SMF in clinical treatment of cancer, pain, diabetes and other diseases. With the development and growing popularity of modern appliances like MRI in hospitals, the potential impact of magnetic fields on human health is invoking increasing concerns. At the same time, SMF has been explored in the treatment of tumor and other diseases for decades. Nevertheless, there are still some reservations and uncertainties about these treatments, which are largely due to the differential biological effects reported in the literature. These experimental inconsistencies are mainly caused by variations such as different magnetic field types, intensities, treatment time, as well as biological samples examined. The second edition added eight new chapters about new progress in this field including impacts of SMFs, magnetism of biomolecules, and potential of SMFs in the management of bone, pain, diabetes, and immune systems. This volume will help clarify some dilemmas in this field and encourage further investigations in order to achieve a better understanding of the biological effects of SMF, aiming for a rational application of SMF in clinical therapy in the near future. The book is useful for scientists, doctors, and students who are interested in magnetic fields and life sciences.
    Materialart: Online-Ressource
    Seiten: XV, 420 p. 1 illus. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9789811988691
    URL: https://doi.org/10.1007/978-981-19-8869-1
    DOI: 10.1007/978-981-19-8869-1
    DDC: 610.72
    Sprache: Englisch
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  • 5
    Online-Ressource
    Online-Ressource
    Deciphering Drug Targets for Alzheimer’s Disease (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biology. ; Neurosciences. ; Biotechnology. ; Drug delivery systems. ; Biomedical Research. ; Biological Sciences. ; Neuroscience. ; Biotechnology. ; Drug Delivery.
    Beschreibung / Inhaltsverzeichnis: Chapter 1.Deciphering New Drug Targets in Alzheimer’s Disease -- Chapter 2. Novel Therapeutic Targets for Treating Alzheimer’s Disease -- Chapter 3. Modified Investigation Tools and Techniques Useful in Alzheimer’s Disease Research -- Chapter 4. Dual Specificity Tyrosine Phosphorylation Regulated Kinase1A (DYRK1A) Inhibitors: The Quest for a Disease-Modifying Treatment for Alzheimer’s Disease -- Chapter 5. β-secretase as a primary drug target of Alzheimer disease: Function, Structure, and Inhibition -- Chapter 6. Endocrine Receptors: The Potential Therapeutic Targets for Alzheimer’s -- Chapter 7. Calcium Channels as a Potential Therapeutic Target for Alzheimer’s Disease -- Chapter 8. Traversing Through the Trajectory of Pathogenic Astrocytes in Alzheimer’s Disease -- Chapter 9. Targeting Mitochondrial Dynamics as a Restorative Approach in the Treatment of Alzheimer’s Disease -- Chapter 10. Epigenetic Therapy for Alzheimer’s Disease -- Chapter 11. Exploring the Diverse Roles of GSK-3ß Kinase in Alzheimer’s Disease -- Chapter 12. Role of Target Fishing in Discovery of Novel Anti-Alzheimer’s Agents: In Silico Applications -- Chapter 13. Multi-Target Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery -- Chapter 14. Investigating the Role of Tau Proteins in Alzheimer’s Disease-From Typical Functioning MAPs to Aberrant Fibrillary Deposits in the Brain -- Chapter 15. The Overview of Drugs Used in Alzheimer’s Disease and Their Molecular Targets.
    Kurzfassung: This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.
    Materialart: Online-Ressource
    Seiten: XV, 381 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819926572
    URL: https://doi.org/10.1007/978-981-99-2657-2
    DOI: 10.1007/978-981-99-2657-2
    DDC: 610.72
    Sprache: Englisch
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  • 6
    Online-Ressource
    Online-Ressource
    Glycosignals in Cancer : Molecular Assembly and Recognition (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical genetics. ; Life sciences. ; Cytology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Life Sciences. ; Cell Biology. ; Internal Medicine.
    Beschreibung / Inhaltsverzeichnis: Part I. Search for novel tumor epitopes related to carbohydrates -- Chapter 1.1. The ganglioside structures: chemistry and biochemistry -- Chapter 1.2. Fucosylated proteins as cancer biomarkers -- Part II. Assembly of glycoconjugates -- Chapter 2.1. Siglec-7 and synthetic sialylpolymer -- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis -- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer -- Part III. Signaling pathways modulated by glycosylation -- Chapter 3.1. Significance of FUT8in pancreatic cancer and others -- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells -- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules -- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells -- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction -- Part V. Clinical trials targeting glycosignals -- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.
    Kurzfassung: This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
    Materialart: Online-Ressource
    Seiten: VI, 238 p. 1 illus. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9789811977329
    URL: https://doi.org/10.1007/978-981-19-7732-9
    DOI: 10.1007/978-981-19-7732-9
    DDC: 610.72
    Sprache: Englisch
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  • 7
    Online-Ressource
    Online-Ressource
    Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID-19 (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Biochemical markers. ; Proteins. ; Metabolism. ; Genomics. ; Biomarkers. ; Proteins. ; Metabolism. ; Genomics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. The COVID-19 Pandemic: SARS-CoV-2 Structure, Infection, Transmission, Symptomology and Variants of Concern -- Chapter 2. Long-term Vaccination and Treatment Strategies for COVID-19 Disease and Future Coronavirus Pandemics -- Chapter 3. Consequences of the Lockdown - Domestic Violence during the COVID-19 Pandemic -- Chapter 4. Psychological distress impact of Coronavirus disease (COVID-19) outbreak on three continents: A systematic review and meta-analysis -- Chapter 5. A Molecular Biomarker-based Triage Approach for Targeted Treatment of Post-COVID-19 Syndrome Patients with Persistent Neurological or Neuropsychiatric Symptoms -- Chapter 6. Genetic Associations with Coronavirus Susceptibility and Disease Severity -- Chapter 7. COVID Diagnostics: from Molecules to Omics -- Chapter 8. Assessing Biomarkers in Viral Infection -- Chapter 9. Proteomic Investigation of COVID-19 Severity During the Tsunamis Second Wave in Mumbai -- Chapter 10. NMR-Metabolomics in COVID-19 Research -- Chapter 11. Potential Biomarkers of Mitochondrial Dysfunction Associated with COVID-19 Infection -- Chapter 12. Red Cell Distribution Width as a Prognostic Indicator for Mortality and ICU Admission in Patients with COVID-19 -- Chapter 13. Predicting the COVID-19 Patients Status using Chest CT Scan Findings: A Risk Assessment Model Based on Decision Tree Analysis -- Chapter 14. Inferring Recombination Events in SARS-CoV-2 Variants In Silico -- Chapter 15. Amplicon-based Nanopore Sequencing of Patients Infected by the SARS-CoV-2 Omicron (B.1.1.529) Variant in India -- Chapter 16. Perspectives on Rapid Antigen Tests for Downstream Validation and Development of Theranostics -- Chapter 17. Machine Learning and COVID-19: Lessons from SARS-CoV-2 -- Chapter 18. The Relationship between Psoriasis, COVID-19 Infection and Vaccination during Treatment of Patients -- Chapter 19. Immunogenicity of Inactivated SARS-CoV-2 Vaccine (BBIBP-CorV; Sinopharm) and Short-term Clinical Outcomes in Vaccinated Solid Organ Transplant Recipients: A Prospective Cohort Study -- Chapter 20. Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective -- Chapter 21. Antiviral Mechanisms of Curcumin and its Derivatives in Prevention and Treatment of COVID-19: A review -- Chapter 22. Evaluation of Curcumin-Piperine Supplementation in COVID-19 Patients Admitted to the Intensive Care: A Double-Blind, Randomized Controlled Trial -- Chapter 23. Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases of COVID-19: A Hypothetical Approach -- Chapter 24. The Potential Effect of Royal Jelly on Biomarkers Related to COVID-19 Infection and Severe Progression -- Chapter 25. Statins: Beneficial Effects in Treatment of COVID-19 -- Chapter 26. Multiplex Immunoassay Approaches Using Luminex® xMAP® Technology for the Study of COVID-19 Disease -- Chapter 27. Rapid Detection of SARS-CoV-2 Variants of Concern by Genomic Surveillance Techniques.
    Kurzfassung: The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.
    Materialart: Online-Ressource
    Seiten: XI, 513 p. 87 illus., 74 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031280122
    Serie: Proteomics, Metabolomics, Interactomics and Systems Biology, 1412
    URL: https://doi.org/10.1007/978-3-031-28012-2
    DOI: 10.1007/978-3-031-28012-2
    DDC: 610.72
    Sprache: Englisch
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  • 8
    Online-Ressource
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    Mechanisms and Emerging Therapies in Tremor Disorders (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Neurology . ; Neurosciences. ; Nervous system Diseases. ; Biomedical Research. ; Neurology. ; Neuroscience. ; Neurological Disorders.
    Beschreibung / Inhaltsverzeichnis: PART I: Fundamental Aspects -- Chapter 1. Definition of Tremor -- Chapter 2. Membrane Mechanisms of Tremor -- Chapter 3 Advances in the Genetics of Human Tremor -- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor -- PART II:Tremor in Clinical Practice -- Chapter 5. Physiologic Tremor -- Chapter 6. Rest Tremor -- Chapter 7. Postural Tremors -- Chapter 8. Isometric Tremor -- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor -- Chapter 10. Cerebellar lesions and tremor -- Chapter 11. Orthostatic Tremor -- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders -- Chapter 13 Tremor in Childhood -- Chapter 14. Metabolic Causes of Tremor -- Chapter 15. Drug-Induced Tremor -- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis -- PART III: Assessment of tremor -- Chapter 17. Signal Processing -- Chapter 18. Diffusion imaging in Tremor -- Chapter 19. The role of the noradrenergic system in tremor pathogenesis -- Chapter 20. Metabolic Networks in Parkinson’s Disease -- PART IV: Therapies -- Chapter 21. Deep brain stimulation for tremor -- Chapter 22 Mechatronic Devices for Upper Limb Tremor.
    Kurzfassung: Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment and provides practical information for daily management. This new edition is informed by the guidelines of the Tremor Task Force of the International Parkinson and Movement Disorders Society. New chapters include Classification of Tremors, Medically Induced Tremors, Resting State fMRI, and Gabaergic Pathways. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced.
    Materialart: Online-Ressource
    Seiten: X, 558 p. 86 illus., 59 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031261282
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-031-26128-2
    DOI: 10.1007/978-3-031-26128-2
    DDC: 610.72
    Sprache: Englisch
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  • 9
    Online-Ressource
    Online-Ressource
    Microplastic Occurrence, Fate, Impact, and Remediation (2023)
    Cham :Springer Nature Switzerland :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Analytical chemistry. ; Toxicology. ; Biomedical Research. ; Analytical Chemistry. ; Toxicology.
    Beschreibung / Inhaltsverzeichnis: Microplastic research publications from 1991 to 2020 -- Characterization and toxicology of microplastics in soils, water and air -- Coral feeding behavior on microplastics -- Microplastics remediation in the aqueous environment -- Removal of environmental microplastics by advanced oxidation processes -- Techniques for removal and degradation of microplastics -- Occurrence and removal of microplastics in wastewater treatment plants -- Microplastic souces, transport, exposure, analysis and removal -- Airborne microplastics in outdoor and indoor environments -- Nanoplastic sources, characterization, ecological impact, remediation and policies -- Microplastics in soil-plant systems.
    Kurzfassung: Microplastics and nanoplastics have been recently found in most environmental media and in living organisms, thus representing a serious health concern of yet poorly known adverse consequences. This book summarizes recent findings on the sources, behavior, transformation, toxicity and remediation of microplastics, with focus on soils, water, wastewater, air, soils, plants and corals. Advanced methods for sampling, characterization, removal and degradation of microplastics.
    Materialart: Online-Ressource
    Seiten: VIII, 282 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031363511
    Serie: Environmental Chemistry for a Sustainable World, 73
    URL: https://doi.org/10.1007/978-3-031-36351-1
    DOI: 10.1007/978-3-031-36351-1
    DDC: 610.72
    Sprache: Englisch
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  • 10
    Online-Ressource
    Online-Ressource
    Textbook of Forensic Science (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Forensic sciences. ; Medical jurisprudence. ; Biomedical Research. ; Forensic Science. ; Forensic Medicine.
    Beschreibung / Inhaltsverzeichnis: Module 1_Introduction to Forensic Science & Crime -- Module 2_Criminalistics -- Module 3_ Forensic Biological Sciences -- Module 4_Forensic Physical Sciences -- Module 5_Forensic Chemical Sciences -- Module 6_Emerging fields in Trends in Forensics.
    Kurzfassung: This textbook provides essential and fundamental information to modern forensics investigations. It discusses criminalistics and crime scene aspects, including investigation, management, collecting and packaging various types of physical evidence, forwarding, and chain of custody. It presents fundamental principles, ethics, challenges and criticism of forensic sciences and reviews the crime typologies, the correlates of crime, criminology, penology, and victimology. It provides a viewpoint on legal aspects, including types of evidence, the procedure in the court and scrutiny of the evidence and experts. The book summarizes forensic serological evidences such as blood, semen, saliva, milk-tears, sweat, vaginal fluids, urine, and sweat. It also provides an overview of forensic examination of different types of evidence and also includes comprehensive detailing of forensic ballistics including firearm classification, bullet comparison and matching. Further, it explores the examinations of drugs, chemicals, explosives, and petroleum products. It focuses on the various aspects of forensic toxicology, including the study of various poisons/toxins, associated signs and symptoms, a fatal dose /fatal period of poisons. The book also emphasizes digital and cyber forensics, including classification, data recovery tools, encryption and decryption methods, image, and video forensics. It is a useful resource for graduate and post-graduate students in the field of Forensic Science.
    Materialart: Online-Ressource
    Seiten: XV, 839 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819913770
    URL: https://doi.org/10.1007/978-981-99-1377-0
    DOI: 10.1007/978-981-99-1377-0
    DDC: 610.72
    Sprache: Englisch
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  • 11
    Online-Ressource
    Online-Ressource
    Approaches for Science Illustration and Communication (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Anatomy. ; Information visualization. ; Biophysics. ; Biomedical Research. ; Anatomy. ; Data and Information Visualization. ; Bioanalysis and Bioimaging.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. The Importance of Integrating the Visual Arts into the Medical Curriculum -- Chapter 2. Using Medical Illustration to Improve Understanding of Endometriosis -- Chapter 3. Editorial Medical and Scientific Illustration -- Chapter 4. Current Approaches in Narrative Medical Visualization -- Chapter 5. Animation for Science Communication: A Description of the Production Process and Contexts for Using Science Animation -- Chapter 6. Effect of the Rings: A Visual Story Design Comparing Three Chemical Characters -- Chapter 7. Diabetes Year One, Random Fluctuations and Mental Goblins: Auto-Ethnographic Pathographies and Medical Comics -- Chapter 8. Playing with Science: Games as a Medium of Science Communication -- Chapter 9. Increasing Microbiology Literacy about the Public Health Threat of Antimicrobial Resistance Through Art-Science Interactions -- Chapter 10. Collaged Creatures: Using Collage Art Practice and Posthuman Ethics to Discuss Bioengineering Hybrids.
    Kurzfassung: This edited book explores the breadth of approaches undertaken by scientists, artists and communicators in their crucial role making science accessible, engaging and impactful. Contemporary approaches in science illustration and visualization include a variety of creative methodologies that are valuable for effective communication, teaching, learning and professional practice. These range in method from anatomical drawings used in medical curricula, to 2D animations and editorial illustrations available in the public realm. They also include unexpected approaches such as the use of tabletop board games, comics and collage in understanding our bodies, emergent health threats and cutting-edge science developments. If you are a scientist seeking to enhance your ability to communicate your research or an artist interested in biomedical visualization, this volume serves as an introduction to contemporary approaches in science illustration and communication. By understanding the creative methods and techniques employed in this field, we can collectively work towards fostering a deeper appreciation of art in science, and continue to captivate and inspire audiences worldwide. .
    Materialart: Online-Ressource
    Seiten: XVI, 252 p. 158 illus., 140 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031416521
    Serie: Biomedical Visualization, 4
    URL: https://doi.org/10.1007/978-3-031-41652-1
    DOI: 10.1007/978-3-031-41652-1
    DDC: 610.72
    Sprache: Englisch
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  • 12
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    Online-Ressource
    Polymeric Biomaterials for Tissue Regeneration : From Surface/Interface Design to 3D Constructs (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Regenerative medicine. ; Biomaterials. ; Biomedical Research. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells -- Part I. Structural Scaffolds and Bio-activation -- Chapter 2. Polymeric and Biomimetic ECM Scaffolds for Tissue Engineering Applications -- Chapter 3. Versatile Hydrogels in Regenerative Medicine -- Chapter 4. Multilayer Microcapsules with Tailored Structures and Properties as Delivery Carriers for Drugs and Growth Factors -- Part II Biomaterials Surfaces/Interfaces and Bio-interactions. Chapter 5. Interactions of Biomaterial Surfaces with Proteins and Cells -- Chapter 6. Surface Modification of Tissue Engineering Scaffolds -- Chapter 7. Gradient Biomaterials and Their Impact on Cell Migration -- Chapter 8. Stem Cell Differentiation Mediated by Biomaterials/Surfaces -- Part III Regeneration of Some Clinic-Targeted Tissues -- Chapter 9. Cartilage Regeneration -- Chapter 10. Skin Regeneration -- Chapter 11. Regeneration of Blood Vessels -- Chapter 12. Cardiac repair and regeneration -- Chapter 13. Nerve Regeneration.
    Kurzfassung: This book reviews state of the art of polymeric biomaterials for regenerative medicine and highlights advances in both fundamental science and clinical practice. It summarizes the latest techniques in polymeric scaffold fabrication, delivery carriers, physiochemical property modulation, as well as their influence on the adhesion and performance of biomolecules, cells, and tissues. It also describes methods for creating biofunctional surfaces/interfaces and subsequently modulating the host response to implantable materials. Lastly, it discusses the applications of biomaterials and constructs in soft-tissue regenerative medicine. It is a valuable resource for materials scientists and engineers wishing to identify research priorities to fulfill clinical needs and provides physicians with insights into emerging novel biomaterials. This integrated approach also offers engineering students a sense of the relevance of materials science in the development of novel therapeutic strategies. In the second edition, most of the chapters are updated according to the latest progress of this research field. A new chapter on nerve regeneration is also included.
    Materialart: Online-Ressource
    Seiten: VIII, 577 p. 1 illus. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9789819969487
    URL: https://doi.org/10.1007/978-981-99-6948-7
    DOI: 10.1007/978-981-99-6948-7
    DDC: 610.72
    Sprache: Englisch
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  • 13
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    Career Options in the Pharmaceutical and Biomedical Industry : An Insider’s Guide (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Vocational guidance. ; Career education. ; School management and organization. ; School administration. ; Biomedical Research. ; Career Counseling. ; Career Skills. ; Organization and Leadership.
    Beschreibung / Inhaltsverzeichnis: Part 1: Setting the scene -- Chapter 1: Life after Academia: Launching your Pharma/Biotech Career -- Chapter 2: Competences for Pharmacists -- Chapter 3: Job and Career Opportunities in the Pharmaceutical Industry: An Overview -- Part 2: Opportunities along the drug/product life cycle -- Chapter 4: Career Opportunities in Toxicology -- Chapter 5: Job Possibilities in Clinical Research -- Chapter 6: How to Get and Develop a Career in a Market Access Role in the Medical Devices Industry -- Chapter 7: Job Opportunities in Pharmaceutical Marketing -- Chapter 8: Working in Medical Affairs and Clinical Operations: Life-Changing Careers -- Chapter 9: The Role of Medical Science Liaison -- Chapter 10: Career Development for Physicians in the Biopharmaceutical Industry -- Part 3: Opportunities in Supportive Functions -- Chapter 11: Job and Career Opportunities in Regulatory Affairs/Science -- Chapter 12: Job Opportunities in Clinical Research Quality Assurance -- Chapter 13: Job Opportunities in Quality Assurance Related to Manufacturing of Medicinal Products -- Part 4: Other Opportunities in the Pharmaceutical and Biomedical Sector -- Chapter 14: Careers Perspective in a Science and Technology Park -- Chapter 15: To be or not to be: Entrepreneurship and Enterprise Creation as a Way to Innovate in Life Sciences -- Chapter 16: How to Become a Successful Hospital and Community Pharmacist -- Part 5: Practical tips and tricks -- Chapter 17: A Successful Career in the Life Sciences Industry: How to Write your Strongest Resumé and Ace that Interview -- Chapter 18: Skill Building for Career Advancement: Public Speaking and Networking -- Chapter 19: Training Opportunities for a Career in the Pharmaceutical and Biomedical Industry/Sector.
    Kurzfassung: Written by dedicated and active professionals from different areas of the pharmaceutical, biomedical, and medtech sectors, this book provides information on job and career opportunities in various life sciences industries. It also contains useful tips to launch your own startup. The pharmaceutical, biomedical and medical technology sectors offer a wide range of employment opportunities to talented and motivated young graduates. However, many of these employment prospects are not well known to early career scientists, who concentrate primarily on the scientific and academic content of their fields of interest. The book is divided into five parts: Part 1 provides an academic perspective that focuses on the specific preparation required in the final years of study to embark on a successful career in the pharmaceutical and biomedical industries. In Part 2, industry experts discuss employment possibilities all along the drug or product life cycle, from discovery research and development to commercialisation. Part 3 follows, highlighting opportunities in support functions such as regulatory affairs or quality assurance. Part 4 focuses on additional opportunities in the wider biomedical sector, while Part 5 contains practical tips and training opportunities for entering the pharmaceutical and biomedical industries. In the epilogue, the authors reflect on this fascinating field and its career prospects. The book offers a multidisciplinary perspective on career opportunities in the pharmaceutical and biomedical industry to a wide range of students and young life scientists. .
    Materialart: Online-Ressource
    Seiten: XXI, 328 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031149115
    URL: https://doi.org/10.1007/978-3-031-14911-5
    DOI: 10.1007/978-3-031-14911-5
    DDC: 610.72
    Sprache: Englisch
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  • 14
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    Tuberculosis : Integrated Studies for a Complex Disease (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Clinical medicine Research. ; Epidemiology. ; Diseases Causes and theories of causation. ; Biomedical Research. ; Clinical Research. ; Epidemiology. ; Pathogenesis.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction on Tuberculosis: Integrated Studies for a Complex Disease -- 2. Global Tuberculosis Epidemiology -- 3. Heterogeneity in Tuberculosis -- 4. The Unequivocal Relationship between Tuberculosis and Tobacco: Integration of Two Maladies -- 5. Relationship between Pre-existing Cancer and Tuberculosis -- 6. Laboratory Diagnosis of Tuberculosis -- 7. The Role of Diagnostic Microdevices in the Fight Against Tuberculosis -- 8. Immunodiagnostics of Tuberculosis: Recent Discoveries -- 9. Role of Bronchoscopy in Diagnostics and Treatment of Tuberculosis -- 10. Diagnosis of Childhood Tuberculosis in Low- and Middle-income Countries -- 11. Pediatric Tuberculosis: Current Evidence for Laboratory Diagnosis -- 12. A Multidisciplinary Approach Towards Finding and Treating All Tuberculosis Patients -- 13. Chemotherapy for Drug-Susceptible Tuberculosis -- 14. The Pharmacokinetic and Pharmacodynamic Properties of Antitubercular Medications -- 15. Immune Approaches In Tuberculosis Treatment -- 16. Inhalation Therapy in Pulmonary Tuberculosis -- 17. Role of Micronutrients in Tuberculosis Management -- 18. Drug Resistance in Tuberculosis: Mechanisms, Diagnosis, New Responses, and the Need for An Integrated Approach -- 19. Resistance in Tuberculosis: Molecular Mechanisms and Modulation -- 20. Personalized Tuberculosis Care for Drug-Resistant Tuberculosis -- 21. Important Targets and Inhibitors of Mycobacterium Tuberculosis -- 22. P-type ATPases: A Relevant Component in Mycobacterium tuberculosis Viability -- 23. The Challenges of Antitubercular Drug Discovery -- 24. Exploring Decaprenylphosphoryl-β-D-ribose 2’-Epimerase 1 (DprE1): A Target for Anti-Tubercular Drugs -- 25. Energy Pathways in Mycobacterium Tuberculosis -- 26. Drug Discovery for Non-Tuberculous Mycobacteria: Recent Updates -- 27. Challenges for Contact Tracing and Tuberculosis Preventive Therapy Scale-up -- 28. Exploring Problematizations Underlying Tuberculosis Control Strategies: A Cross-Country Analysis of India and Kenya -- 29. Challenges in Prevention and Management of Tuberculosis -- 30. Tuberculosis in Contacts and Healthcare Workers -- 31. Tuberculosis Among People Who Use Drugs: Multilevel Considerations for Prevention, Diagnosis, and Treatment -- 32. Anti-Tumor Necrosis Factor-α Antagonists and Tuberculosis -- 33. Breast Tuberculosis -- 34. Central Nervous System Tuberculosis: Pathogenesis, Diagnosis, and Management -- 35. Pleural Tuberculosis -- 36. Ocular Tuberculosis -- 37. Ocular Tuberculosis: Biomarkers for Risk Stratification -- 38. Bone and Joint Tuberculosis -- 39. Abdominal Tuberculosis: Pathogenesis, Clinical Features, and Diagnosis -- 40. Bovine Tuberculosis at The Interface of Cattle, Wildlife, and Humans -- 41. Evolution and Molecular Characteristics of Mycobacterium Tuberculosis and Mycobacterium Bovis -- 42. Animal Tuberculosis: Gross Lesions and Anatomopathological Diagnosis -- 43. Estimation of Microbial Mutation Rates in Tuberculosis Research -- 44. The Role of Epigenetics in the Development of Anti-Tuberculosis Drug Resistance -- 45. Multiomics Integration of Tuberculosis Pathogenesis -- 46. Lung Microbiome in Tuberculosis -- 47. The Correlation of Microbiota and Host Epigenome in Tuberculosis -- 48. The Pathogenesis and Progression of Sarcoidosis from The Standpoint of Tuberculosis -- 49. Tuberculosis: A Historical and Global Bioethical Perspective -- 50. The Problem of Tuberculosis: Myths, Stigma, and Mimics -- 51. Tuberculosis: Integrated Studies for a Complex Disease 2050.
    Kurzfassung: Tuberculosis have been documented since antiquity and the search of the microbes that cause this disease started more than three hundred years ago. Nevertheless, tuberculosis remains an important global health issue, with millions of people affected per year in addition to millions that remain undiagnosed and untreated. Patients with tuberculosis face the full range of recurrence, reinfection, and resistance due to diagnostic, prophylactic, and therapeutic procedures that are not as effective as they should be. In addition, variability in susceptibility to tuberculosis pose a complex problem with numerous interrelated variables. This volume is devoted to the understanding of Tuberculosis focusing on its heterogeneity, its transmission, manifestations, related conditions, diagnosis, treatments, drug resistance and prevention.
    Materialart: Online-Ressource
    Seiten: XXIV, 1116 p. 363 illus., 239 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031159558
    Serie: Integrated Science, 11
    URL: https://doi.org/10.1007/978-3-031-15955-8
    DOI: 10.1007/978-3-031-15955-8
    DDC: 610.72
    Sprache: Englisch
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  • 15
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    Online-Ressource
    Integrated Science of Global Epidemics (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Public health. ; Epidemiology. ; Medical policy. ; Medicine, Preventive. ; Health promotion. ; Biomedical Research. ; Public Health. ; Epidemiology. ; Health Policy. ; Health Promotion and Disease Prevention.
    Beschreibung / Inhaltsverzeichnis: Introduction on Integrated Science of Global Epidemics -- Emerging Viral Infections in Human Population -- One Health as An Integrated Approach: Perspectives from Public Services for Mitigation of Future Epidemics -- Multipronged Approach to Combat COVID-19: Lessons from Previous Pandemics for the Future -- Response to Disease Outbreaks in Africa: A Call to Build Resilient Health Systems -- Navigating Global Public Influenza Surveillance Systems for Reliable Forecasting -- Three Respiratory Syndrome Epidemics (SARS, MERS, COVID-19) in Two Decades: Clinical Epidemiological Considerations -- Epidemic in Complex Networks and Some Ideas About the Impact of Isolation Strategies in the Context of the COVID-19 Pandemic -- Optimal Control: Application and Applicability in Times of Pandemics -- Analysis of A COVID-19 Model Implementing SocialDistancing as An Optimal Control Strategy -- Impact of Policy Implementations on the Propagation of COVID-19 Before Vaccine -- Environmental Factors Associated with Global Pandemic Transmission and Morbidity -- Urbanization and the Epidemiology of Infectious Diseases: Towards the Social Framing of Global Responses -- Pandemics and Mass Casualties: Cornerstones of Management -- Social Marketing Contributions to Mitigate Global Epidemics -- The Significance of Super Intelligence of Artificial Intelligence Agencies in the Social Savageries of COVID-19: An Appraisal -- Integration of Sex and Gender Approaches in National Ethics Committees’ Mandate to Appraise COVID-19 Research Protocols: Lessons from West Africa -- Psychology, Law, Ethics, Telehealth, and the Global Pandemic -- Physical Inactivity, Sedentarism, and Low Fitness: A Worldwide Pandemic for Public Health -- The Global Epidemic of Diabesity: Are We Heading for An Unsustainable Future? -- Nutrition, Function, and Quality of Life in Older Adults Socially Isolated Due to the COVID-19 Pandemic: A Focus on Telehealth Interventions -- Africa’s Response to Pandemics -- Vaccine Hesitancy and Refusal: History, Causes, Mitigation Strategies -- Vaccine Compliance versus Trust in a Pandemic -- Child Development in A Crisis: A Pandemic -- HIV/AIDS Problems and Policies in Adolescent Population -- Addressing Needs of Foreign Schoolchildren to Combat a Global Epidemic of Dengue Virus Infection: Transnational and Trans-sectoral Initiatives -- Integrated Science of Global Epidemics 2050.
    Kurzfassung: The “Integrated Science of Global Epidemics” is the new proposed volume of Integrated Science Book series, aiming to publish the results of the most updated ideas and reviews on Global Epidemics. The whole world is suffering from complex problems, border less problems and global solution should be developed. The Integrated Science of Global Epidemics aims to highlight the combination of different disciplines, including formal sciences, physical-chemical sciences and engineering, biological sciences, medical sciences, and social sciences, to deal with complex problems such as global epidemics. This contributed volume could be used as guidelines for the entire scientific community and policy makers to successfully face these global threats. Chapter 27 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Materialart: Online-Ressource
    Seiten: XII, 623 p. 170 illus., 144 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031177781
    Serie: Integrated Science, 14
    URL: https://doi.org/10.1007/978-3-031-17778-1
    DOI: 10.1007/978-3-031-17778-1
    DDC: 610.72
    Sprache: Englisch
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  • 16
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    Online-Ressource
    Grant writing for medical and healthcare professionals (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Research Methodology. ; Clinical medicine Research. ; Biomedical Research. ; Research Skills. ; Clinical Research.
    Beschreibung / Inhaltsverzeichnis: Section I: Understanding Grant Writing: What is your Aim (Ambition-Interest-Mission), and what you want to do -- What is a grant? How to prepare for writing a grant proposal application -- Funders Perspective: What the funding body expects from researchers? -- Funding organizations for science and healthcare -- Obtaining letters of support -- Section II: The process for grant writing: Writing a Grant Proposal for a Single Centre Study: step-by-step approach -- Budgeting the project-detailing the required funding and expenditure -- Proving the competency of the researcher and the adequacy of the infrastructure to carry out the research -- Agreement and MOU – ethical and legal aspects of funding for healthcare research -- Write an impressive cover page (Covering letter) and abstract for the grant proposal application -- Surveillance plan and site visit – Roles and rights of the researcher and the funding agency -- Sources of funding and acknowledgment – Good Clinical Practice Guidelines -- Writing a grant proposal for a Collaborative study -- Checklist for grant proposal – Mandatory elements -- Tips for improvising the chance of getting the grant -- Dealing with The Rejected Grant Proposal- Learning From The Mistakes -- Section III: Grant writing for specific regional funding organizations: Preparing a grant proposal for medical research in the UK -- Preparing a grant proposal for the USA -- Preparing a Grant Proposal for Australia -- Proposal Writing for Grant Application in Malaysia -- Grant writing for other Asian countries.
    Kurzfassung: Conducting research requires resources to meet the research need. The resources in the research institutes/ centers are often inadequate, limiting the research outcome. Research grants help overcome those limitations and help the researchers carry out quality research without any restriction. Grant proposal writing is an essential skill to be mastered by every researcher. However, the majority of the medical schools, except the few research institutes, do not have a structured learning module for obtaining grants. On most occasions, the skill of writing grant proposals goes by self-learning. For students, it is burdening due to the tremendous time consumed to learn the craft of writing the grant proposal and the exhausting clinical and academic work. This book is carefully prepared to keep in mind the difficulties faced by the young researchers and the students concerning choosing a funding agency, grant makers' expectations, budgeting, surveillance and site visits, rights of the researcher and the funding agency, and ethical and legal aspects of obtaining the grant. The book also covers the alternate plan for partial funding or interruption of the financing, reporting the source of funding and acknowledgment, good clinical practice guidelines, and dealing with the rejected grant proposal. The research projects are often dropped or modified extensively due to the limited resources in the existing facility. The researchers are forced to compromise the research objective due to expensive requirements. There is a shortage of awareness regarding the availability of funding and grant for the conduct of research. Even if the researchers are aware of obtaining the financing, there is a lack of training in grant proposal writing, which is essential in getting the research funding. This book on grant proposal writing for medical and healthcare professionals covers such difficulties and deficiencies. It will provide complete companionship from knowing the funding agency to obtaining the grant. .
    Materialart: Online-Ressource
    Seiten: XX, 247 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811970184
    URL: https://doi.org/10.1007/978-981-19-7018-4
    DOI: 10.1007/978-981-19-7018-4
    DDC: 610.72
    Sprache: Englisch
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  • 17
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    Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2 : The Path to Bedside Management (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Neurology . ; Internal medicine. ; Immunology. ; Biomedical Research. ; Biomedical Research. ; Neurology. ; Internal Medicine. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Malignant Glioma -- Chapter 2. Benign Glioma -- Chapter3. Meningioma and Other Meningeal Tumors -- Chapter4. Epondymomas in Pediatric and Adults -- Chapter5. Medulloblastomas in Pediatric and Adults -- Chapter6. Benign and Malignant Tumors of The Pineal Region -- Chapter7. The Tumors of Choroid Plexus and Other Ventricular Tumors -- Chapter8. Embryonal Tumors of The Central Nervous System with Multilayered Rosettes and Atypical Teratoid/Rhabdoid Tumors -- Chapter9. Glioneuronal and Neuronal Tumors of the Central Nervous System -- Chapter10. Benign and Malignant Tumors of the Pituitary Gland -- Chapter11. Craniopharyngioma in Pediatric and Adults -- Chapter12. Schwannomas of Brain and Spinal Cord -- Chapter13. Other Nerve-Sheet Tumors of Brain and Spinal Cord -- Chapter14. Hemangioblastomas and Other Vascular Originating Tumors of Brain or Spinal Cord -- Chapter15. Brain and Spinal Cord Tumors of Embryonic Origin -- Chapter16. Brain and Spinal Tumors Originating from the Germ Line Cells -- Chapter17. Benign Brain and Spinal Tumors Originating from Bone or Cartilage -- Chapter18. Benign Spinal Tumors -- Chapter19. Other Less Prevalent Tumors of the Central Nervous System -- Chapter20. Brain and/or Spinal Cord Tumors Accompanied with Other Diseases or Syndromes -- Chapter21. Psychological and Psychiatric Aspects of Brain and Spinal Cord Tumors -- Chapter22. A Brief Explanation on Surgical Approaches for Treatment of Different Brain Tumors.
    Kurzfassung: This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5–9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences. The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.
    Materialart: Online-Ressource
    Seiten: XXIX, 739 p. 287 illus., 159 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031237058
    Serie: Advances in Experimental Medicine and Biology, 1405
    URL: https://doi.org/10.1007/978-3-031-23705-8
    DOI: 10.1007/978-3-031-23705-8
    DDC: 610.72
    Sprache: Englisch
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  • 18
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    Novel Technologies in Biosystems, Biomedical & Drug Delivery (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Drug delivery systems. ; Genetics Research. ; Imaging systems in biology. ; Biology Technique. ; Biomedical Research. ; Drug Delivery. ; Genetics Research. ; Biological Imaging. ; Biological Techniques.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Editorial: Biosystems -- 2. Potential of Biotechnology in cancer management -- 3. Biosimilars: Promising and Rapidly Emerging Biotherapeutics -- 4. Applications of Nanomaterials in Medicine: Current status and future scope -- 5. Biomedical Applications of Nanofluids in Drug Delivery.
    Kurzfassung: The book gives an insight into the theoretical background, conceptual understanding, latest developments, and applications in the field of pharmaceuticals in general and drug design, discovery, biosystems, and biomedical and drug delivery technologies in particular . Knowledge is drawn from various disciplines such as Chemistry, Biology, Material Science and Engineering, Statistics, Biomedicine, and Genetics . A host of applications like bio-imaging, novel biological agents, testing, characterization and validation of drugs, computer-based models in drug design, and application of statistical tools in data analysis, design, and development of drug delivery systems, and ecosystems are dealt with in detail. The said book undoubtedly confirms the requirements of the postgraduate students, research scholars, academicians, scientists, and researchers from the academia, pharmaceutical, biotechnology, and chemical engineering domain. The book covers a conceptual understanding of the exploration of drugs in tandem with intended uses, sound ecosystem development, and carriers for drug and supplement delivery.
    Materialart: Online-Ressource
    Seiten: XX, 289 p. 58 illus., 48 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819952816
    URL: https://doi.org/10.1007/978-981-99-5281-6
    DOI: 10.1007/978-981-99-5281-6
    DDC: 610.72
    Sprache: Englisch
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  • 19
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    Cognitive Functioning in Schizophrenia: Leveraging the RDoC Framework (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical sciences. ; Drug development. ; Pharmacology. ; Genetics Research. ; Clinical medicine Research. ; Biochemical markers. ; Translational Research. ; Preclinical Research. ; Pharmacology. ; Genetics Research. ; Clinical Research. ; Biomarkers.
    Beschreibung / Inhaltsverzeichnis: MATRICS – an update -- Cognitive [Computational] Neuroscience Test Reliability and Clinical Applications for Serious mental illness (CNTRaCS) Consortium: Progress and Future Directions -- Attention in Schizophrenia -- Perceptual Functioning -- Episodic Memory and Schizophrenia: From Characterization of Relational Memory Impairments to Neuroimaging Biomarkers -- Working Memory in People with Schizophrenia -- "Targeting Frontal Gamma Activity with Neurofeedback to Improve Working Memory in Schizophrenia" -- Cognitive Dysfunction as a Risk Factor for Psychosis -- Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity -- Developmental manipulation-induced changes in cognitive functioning -- Genetic underpinnings of cognitive dysfunction in schizophrenia -- Primate models of cognitive deficit re schizophrenia -- Olfactory cognitive deficits -- Medication/Anticholinergic burden impacting cognition in schizophrenia An Update on Treatment of Cognitive Impairment Associated with Schizophrenia -- Cannabis & cognition -- Sex/gender differences -- Neuroinflammation linked to cognition.
    Kurzfassung: This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia. The work on cognition in schizophrenia from the past 20 years is highlighted, and emphasis throughout the book is placed on utilizing the Research Domain Criterion framework. Thus, the book also covers animals work relevant to schizophrenia that assesses behaviors utilizing the same framework, enabling mechanistic studies and highlighting potential biomarkers of function. The book also includes important areas of research in the field of cognitive function in schizophrenia that have received less attention, such as cognitive side-effects of current treatments and olfactory-based cognition. Altogether, the book provides a translational perspective of the most-up-to-date research on cognition in schizophrenia to-date, but with identification of novel directions for research initiatives.
    Materialart: Online-Ressource
    Seiten: XII, 497 p. 70 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031264412
    Serie: Current Topics in Behavioral Neurosciences, 63
    URL: https://doi.org/10.1007/978-3-031-26441-2
    DOI: 10.1007/978-3-031-26441-2
    DDC: 610.72
    Sprache: Englisch
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  • 20
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    Molecular Medicine : How Science Works (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Genomics. ; Cancer. ; Immunology. ; Nutrition   . ; Physiology. ; Biomedical Research. ; Genomics. ; Cancers. ; Immunology. ; Nutrition. ; Physiology.
    Beschreibung / Inhaltsverzeichnis: 1. The human genome and its variations -- 2. Gene expression and chromatin -- 3. The basal transcriptional machinery -- 4. Transcription factors and signal transduction -- 5. A key transcription factor family: Nuclear receptors -- 6. DNA methylation -- 7. Histone modifications -- 8. Chromatin remodeling and organization -- 9. Regulatory impact of non-coding RNA -- 10. Genome-wide principles of gene regulation -- 11. Epigenetics in development -- 12. Epigenetics and aging -- 13. Epigenetics and disease -- 14. Cells and tissues of the immune system -- 15. Innate immunity and inflammation -- 16. Adaptive immunity and antigen receptor diversity -- 17. B cell immunity: BCRs, antibodies and their effector functions -- 18. Antigen-presenting cells and MHCs -- 19. T cell immunity: TCRs and their effector functions -- 20. Immunity to bacterial pathogens and the microbiome -- 21. Immunity to viral pathogens and the virome -- 22. Tolerance and transplantation immunology -- 23. Immunological hypersensitivities: Allergy and autoimmunity -- 24. Introduction to cancer -- 25. Oncogenes, signal transduction and the hallmarks of cancer -- 26 Tumor suppressor genes and cell fate control -- 27. Multistep tumorigenesis and genome instability -- 28. Cancer genomics -- 29. Cancer epigenomics.-30. Aging and cancer -- 31. Tumor microenvironment -- 32 Metastasis and cachexia -- 33. Cancer immunology -- 34 Architecture of cancer therapies -- 35 Nutrition and common diseases -- 36 Interference of the human genome with nutrients -- 37. Nutritional epigenetics, signaling and aging -- 38. Chronic inflammation and metabolic stress -- 39. Obesity -- 40. Insulin resistance and diabetes -- 41. Heart disease and the metabolic syndrome -- 42 Epigenetics, inflammation and disease.
    Kurzfassung: The fascinating area of molecular medicine provides a molecular and cellular description of health and disease. Starting with the understanding of gene regulation and epigenetics, i.e., the interplay of transcription factors and chromatin, this book will provide an fundamental basis of nearly all processes in physiology, both in health as well as in most common disorders, such as cancer, diabetes as well as in autoimmune diseases. Most non-communicable human diseases have a genetic (= inherited) as well as an epigenetic component. The later one is based on our lifestyle choices and environmental exposures. Many common diseases, such as type 2 diabetes, can be explained only to some 20% via a genetic predisposition. We cannot change the genes that we are born with but we can take care of the remaining 80% being primarily based on our epigenome. Therefore, there is a high level of individual responsibility for staying healthy. Thus, not only biologists and biochemists should be aware of this topic, but all students of biomedical disciplines will benefit from being introduced into the concepts of molecular medicine. This will provide them with a good basis for their specialized disciplines of modern life science research. The book is subdivided into 42 chapters that are linked to a series of lecture courses in “Molecular Medicine and Genetics”, “Molecular Immunology”, “Cancer Biology” and “Nutrigenomics” that is given by one of us (C. Carlberg) in different forms since 2002 at the University of Eastern Finland in Kuopio. This book represents an updated version and fusion of the books textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8). “Molecular Immunology: How Science Works” (ISBN 978-3-030-XXX), “Cancer Biology: How Science Works” (ISBN 978-3-030-75699-4) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4). By combining basic understanding of cellular mechanism with clinical examples, the authors hope to make this textbook a personal experience. A glossary in the appendix will explain the major specialist’s terms.
    Materialart: Online-Ressource
    Seiten: XXXIV, 700 p. 301 illus., 300 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031271335
    URL: https://doi.org/10.1007/978-3-031-27133-5
    DOI: 10.1007/978-3-031-27133-5
    DDC: 610.72
    Sprache: Englisch
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  • 21
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    Remote Sensing of Urban Green Space (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Geographic information systems. ; Sustainability. ; Environmental monitoring. ; Geography. ; Geographical Information System. ; Sustainability. ; Environmental Monitoring. ; Regional Geography.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Remote Sensing Data Preprocessing Technology -- Remote Sensing Extraction Technology of Urban Vegetation Information -- Measurement Technology of Two-Dimensional Urban Green Space -- Measurement Technology of Three-Dimensional Urban Green Space -- Construction Technology of Multi-Scale Perception Model of Urban Green Space -- Evaluation Technology of Remote Sensing in Urban Green Space.
    Kurzfassung: This book presents a systematic study of urban green space remote sensing from multi-dimensional and multi-scale technologies. On the basis of introducing the connotation, science and application value of urban green space, this book focuses on the two-dimensional and three-dimensional information extraction technology of urban vegetation, two-dimensional and three-dimensional measurement technology of urban green space and multi-scale perception technology and discusses the remote sensing evaluation method of urban green space. By exploring the technical advantages of ‘satellite remote sensing + aerial remote sensing + near-ground remote sensing’, urban green space remote sensing promotes the development of urban vegetation research from two-dimensional to three-dimensional observation, so that the quantity, quality and human perception of urban vegetation can be measured. In each chapter, an individual technology/method is introduced, and several cases are cited to demonstrate its practical application. This book offers a valuable reference guide for practitioners in urban planning, landscape greening, environmental protection and urban management, as well as teachers and graduate students engaged in urban remote sensing research.
    Materialart: Online-Ressource
    Seiten: XVI, 240 p. 164 illus., 133 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819907038
    URL: https://doi.org/10.1007/978-981-99-0703-8
    DOI: 10.1007/978-981-99-0703-8
    DDC: 910.285
    Sprache: Englisch
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  • 22
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    Socio-Environmental Research in Latin America : Interdisciplinary Approaches Using GIS and Remote Sensing Frameworks (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Geographic information systems. ; Human geography. ; Environmental management. ; Geographical Information System. ; Human Geography. ; Environmental Management.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Interdisciplinarity, GIScience, and Socio-environmental Research in Latin America -- Chapter 2. Using Spatial Time-series and Field Data to Understand Cultural Drivers of Land Change: Connecting Land Conflict and Land Change in Eastern Amazonia -- Chapter 3. Crossing Boundaries: Transboundary Geographic Information in the Amazon Borderlands of Peru and Brazil -- Chapter 4. Territorial Implications of Economic Diversification in the Waorani Ancestral Lands -- Chapter 5. New Insights on Water Quality and Land Use Dynamics in the Napo Region of Western Amazonia -- Chapter 6. From Mapping to Guiding: An Emergent Framework for the Multiple Uses of Remote Sensing and GIScience in Socio-Environmental Research in the Peruvian Andes -- Chapter 7. The Use of Remote Sensing in Air Pollution Control and Public Health -- Chapter 8. Human-environmental Interactions and their Impacts on Temperate Forests in the Exploradores Valley in Western Patagonia -- Chapter 9. El Chaltén, Argentine Patagonia: A successful Combination of Conservation and Tourism? -- Chapter 10. GIS Approaches to Environmental Justice in Mexico’s Oil and Gas Production Zones with Implications for Latin America -- Chapter 11. Contributions to Socio-Environmental Research through Participatory GIS in Archaeology -- Chapter 12. Comparing Volunteered Data Acquisition Methods on Informal Settlements in Mexico City and São Paulo: a Citizen Participation Ladder for VGI -- Chapter 13. CHALLENGES AND OPPORTUNITIES Interdisciplinary GIScience Research on Human-environment Dynamics in Latin America.
    Kurzfassung: This contributed volume presents relevant examples of socio-environmental research that highlight the challenges and opportunities of using geotechnologies in interdisciplinary settings across the vast, culturally, and environmentally mega-diverse region known as Latin America. While remote sensing has been mostly used for mapping and monitoring physical features, geographic information systems open up opportunities for the integration of socio-economic and environmental data collected through individual and community-based surveys, in-situ measurements, and other participatory research techniques to offer additional analytically grounded power when evaluating socio-environmental processes that shape Latin American landscapes. The topics addressed in this book include deforestation and land degradation, borderlands dynamics, agriculture and agroecological systems, environmental conservation and development, public health, tourism, environmental justice, archeology, volunteered geography and urban planning, among others. The book is intended for academics, graduate and undergraduate classrooms, and general audiences with interest in Latin America and the socio-environmental issues that threaten the sustainability of the region and local communities. The book will also appeal to practitioners, managers, and policy makers interested in the application of geo-technologies and field-based research to address complex socio-environmental problems in the Global South. .
    Materialart: Online-Ressource
    Seiten: XIX, 294 p. 78 illus., 73 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031226809
    Serie: The Latin American Studies Book Series,
    URL: https://doi.org/10.1007/978-3-031-22680-9
    DOI: 10.1007/978-3-031-22680-9
    DDC: 910.285
    Sprache: Englisch
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  • 23
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    Applications of Remote Sensing and GIS Based on an Innovative Vision : Proceeding of The First International Conference of Remote Sensing and Space Sciences Applications, Egypt 2022 (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Geographic information systems. ; Environmental geography. ; Physical geography. ; Environmental management. ; Geographical Information System. ; Integrated Geography. ; Earth System Sciences. ; Environmental Management.
    Beschreibung / Inhaltsverzeichnis: Development of Reconfigurable Low-Power Measuring IoT Device for Detecting Common Radioactive Elements for Earth and Space Applications -- RECO-FSCA: Reconfigurable Low-Power Implementation of Fprime-Software for CubeSats Applications -- Autonomous Payload Imaging System for Remote Sensing Applications -- Plasma Space Debris Removal System – NIRCSAT-X -- Heat Energy Storage Module for Thermal Management of Small Satellites In Low Earth Orbit Thermal Conditions.
    Kurzfassung: This book covers various aspects of remote sensing and geographic information systems, from the perspective of earth and environmental sciences. The theme of applications of remote sensing and geographic information systems for the purposes of sustainable development highlights the innovative usage of space imaged spectral data in soil characterization. This book merges the selected contributions to the First International Conference of Remote Sensing and Space Sciences Applications (Egypt 2022) aiming to promote the latest findings on the development of Space Technologies and Applications.
    Materialart: Online-Ressource
    Seiten: XIV, 441 p. 168 illus., 157 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031404474
    Serie: Springer Proceedings in Earth and Environmental Sciences,
    URL: https://doi.org/10.1007/978-3-031-40447-4
    DOI: 10.1007/978-3-031-40447-4
    DDC: 910.285
    Sprache: Englisch
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  • 24
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    Earth Data Analytics for Planetary Health (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Geographic information systems. ; Environmental health. ; Public health. ; Sustainability. ; Geographical Information System. ; Environmental Health. ; Public Health. ; Sustainability.
    Beschreibung / Inhaltsverzeichnis: Topic 1. Environmental Quality Monitoring -- Chap1: Applications of Remote Sensing for Air Pollution Monitoring in Thailand: An Early Warning for Public Health -- Chap2: A novel evaluation of air pollution impact from stationary emission sources to ambient air quality via time-series Granger causality -- Chap3: Groundwater Recharge, Monitoring and Finding Suitable Areas for Groundwater Recharge in Northeast Thailand -- Topic 2. Environmental Changes and Health -- Chap4: Health benefits of air pollution reduction during the COVID-19 lockdown period in Thailand using a machine learning algorithm -- Chap5: Satellite-Derived Vegetation Indices as A Criterion for Assessing Green Exposure that is Related to Human Health Burdens -- Chap6: Five common myths about land use change and infectious disease -- Topic 3. Data and Methodological Issues for Health Studies -- Chap7: Geospatial Environmental Data for Planetary Health Applications -- Chap8: Delineating zones of disease diffusion from the amenity-sharing network in Peninsular Malaysia -- Chap9: Approaches for spatial and temporal-spatial clustering analysis in avian influenza outbreaks -- Chap10: Detecting urban form using remote sensing: spatiotemporal research gaps for sustainable environment and human health.
    Kurzfassung: Planetary health involves complex spatial–temporal interactions among agents, hosts, and earth environment. Due to rapid technical development of geomatics, including geographic information systems (GIS) and remote sensing (RS) in the era of big data analytics, therefore, earth data analytics has become one of the important approaches for monitoring earth surface process and measuring of the effects of environment changes on all humans and other living organisms on earth. Various methods in earth data analytics, including spatial–temporal statistics, spatial evolutionary algorithms, remote sensing image analysis, wireless geo-sensors, and location-based analytics, are an emerging discipline in understanding complex interactions in planetary health. This edited book provides a broad focus on methodological theories of earth data analytics and their applications to measuring the process of planetary health, with the goal to build scientific understanding on how geospatial analytics can provide valuable insights in measuring environmental risks in Southeast Asian regions. It is collection of selected papers covering both theoretical and empirical studies focusing on topics relevant to spatial perspectives on planetary health and environmental exposure studies. The book is written for senior undergraduates, graduate students, lecturers, and researchers in applications of geospatial technologies for public health and environmental studies.
    Materialart: Online-Ressource
    Seiten: IX, 217 p. 60 illus., 47 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811987656
    Serie: Atmosphere, Earth, Ocean & Space,
    URL: https://doi.org/10.1007/978-981-19-8765-6
    DOI: 10.1007/978-981-19-8765-6
    DDC: 910.285
    Sprache: Englisch
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  • 25
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    Temporal and Spatial Environmental Impact of the COVID-19 Pandemic (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Geographic information systems. ; Natural disasters. ; Environmental sciences Social aspects. ; Atmospheric science. ; Geographical Information System. ; Natural Hazards. ; Environmental Social Sciences. ; Atmospheric Science.
    Beschreibung / Inhaltsverzeichnis: Overview Of Geospatial Science And Technology -- Geospatial Appraisal Of Vegetation Health And Air Quality Of Delhi During Pre And Post Lockdown Phase Through Multi-Criteria Decision Model -- Pandemic Effect Of Covid-19: Identification, Present Scenario And Preventive Measures -- Impact Of Lockdown (Covid-19) On Air Pollution In India -- Impact Of Covid-19 Pandemic On Environmental Awareness: A Case Study Of Hyderabad City -- Examination Of Radiation Distribution And Its Relation With Stress Degree Day Index In Some Crops Of Yamne River Catchment In Arunachal Pradesh During Pre And Post Covid Times -- Covid 19 And Its Impact On Urban Health Care System -- Impact Of Covid-19 Pandemic On Education Sector Of Kashmir Valley Its Challenges And Future Prospects -- A Study On Socio-Economic Impact Of Covid 19 Pandemic On Tour Operators Of Vishakhapatnam City, Andhra Pradesh -- A Study On Problems Faced By The Street Vendors In Hyderabad City Post Covid-19 Pandemic.
    Kurzfassung: This book identifies, evaluates and reports the impacts of the COVID-19 pandemic on the physical, biological and socioeconomic environment, using the science and technology of geoinformatics. It encourages the environmental considerations in the future city and policy planning and decision-making. For example, according to the World Health Organization, 80% of people living in cities are exposed to polluted air that exceeds healthy levels. City planners have applied the developing concepts of sustainability to modern debates over how cities and regions should be reviewed, regenerated and reformed since the introduction of the concept in developmental science. During the COVID-19 pandemic, a remarkable drop in air pollution has been observed in India and other countries, which has accelerated the shift to green and sustainable development. Geoinformatics can provide solutions and resources for local, sustainable activities in education, health, sustainable agriculture, resource management and related fields. This book serves researchers in a variety of areas, including hazards, land surveys, remote sensing, cartography, geophysics, geology, natural resources, environment and geography.
    Materialart: Online-Ressource
    Seiten: X, 155 p. 68 illus., 67 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819919345
    Serie: Advances in Geographical and Environmental Sciences,
    URL: https://doi.org/10.1007/978-981-99-1934-5
    DOI: 10.1007/978-981-99-1934-5
    DDC: 910.285
    Sprache: Englisch
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  • 26
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    Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 1 : Neuroimmunology and Neurogenetics (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical genetics. ; Biomedical Research. ; Biomedical Research. ; Biomedical Research. ; Medical Genetics.
    Beschreibung / Inhaltsverzeichnis: Chaptre 1. Brain and Spinal Cord Tumors Among the Life-Threatening Health Problems: An Introduction -- Chaptre 2. Epidemiology of Brain and Spinal Cord Tumors -- Chaptre 3. The Role of Neuro-inflammation and Innate Immunity in Pathophysiology of Brain and Spinal Cord Tumors -- Chaptre 4. The Role of Cellular Immunity and Adaptive Immunity in Pathophysiology of Brain and Spinal Cord Tumors -- Chaptre 5. Immunotherapy as a New Therapeutic Approach for Brain and Spinal Cord Tumors -- Chaptre 6. Cell of Origin of Brain and Spinal Cord Tumors -- Chaptre 7. The Role of Bioinformatics and Imaging Models in Tumorigenesis and Treatment Response of Brain and Spinal Cord Neoplasms -- Chaptre 8. The Role of Epigenetics in Brain and Spinal Cord Tumors -- Chaptre 9. Stem Cells and Targeted Gene Therapy in Brain and Spinal Cord Tumors -- Chaptre 10. Nutrition and Diet: A Double-Edged Sword in Development and Treatment of Brain Tumors -- Chaptre 11. The Role of Nanotechnology in Brain Tumors -- Chaptre 12. The Role of Nanotechnology in Spinal Cord Tumors -- Chaptre 13. The Economic Burden of Malignant Brain Tumors.
    Kurzfassung: Brain tumors comprise about 5–9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well. Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment. The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.
    Materialart: Online-Ressource
    Seiten: XX, 231 p. 30 illus., 16 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031147326
    Serie: Advances in Experimental Medicine and Biology, 1394
    URL: https://doi.org/10.1007/978-3-031-14732-6
    DOI: 10.1007/978-3-031-14732-6
    DDC: 610.72
    Sprache: Englisch
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  • 27
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    Cognizance of Schizophrenia:: A Profound Insight into the Psyche (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Neurosciences. ; Biology. ; Molecular biology. ; Psychiatry. ; Biomedical Research. ; Neuroscience. ; Biological Sciences. ; Molecular Biology. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: 1. Understanding schizophrenia: introductory aspect of the mental disorder from various perspectives -- 2. Genetic mutations and Alternative splicing in schizophrenia -- 3. Understanding the Chemical Interactions in the Brain of Schizophrenia Patients -- 4. A diagnostic perspective of schizophrenia: from past to present -- 5. Is it schizophrenia or not? - Different Biological characterization -- 6. A neurobiological aspect of schizophrenia and the relationship between neurological disorders: depression, anxiety, epilepsy -- 7. Clinical treatment available for schizophrenia -- 8. Insights into the neuro-pharmacological treatment of schizophrenia: past, present, and future -- 9. Managing Schizophrenia – A Challenge for Physicians -- 10. Pharmacotherapy and Emerging Treatment Strategies for Schizophrenia -- 11. Alternative Therapies used in Schizophrenia -- 12. Different phases of schizophrenia patients: from the psychological perspective -- 13. Stigmatizing Attitudes Towards Patients with Schizophrenia Among Medical Professionals and General Population -- 14. Rehabilitation of Schizophrenia-Practical Interventions -- 15. Consumption of Cannabis: A risk factor or a therapeutic agent for patients with Schizophrenia -- 16. Medical Imaging and Schizophrenia: A Study on State-of-art Applications -- 17. Schizophrenia and its Effect on Marital Satisfaction -- 18. The mortality rate in schizophrenia.
    Kurzfassung: This book provides the reader with a thorough understanding of schizophrenia as a complex brain disorder by explaining the various aspects investigated for its cognizance from epigenetics to chemistry and physics to computational approaches. The book covers the key notions of schizophrenia from a variety of facets such as neurogenetics, neurochemistry, neuropharmacology, neurobiology, psychotherapy, psychiatric treatment, cognitive studies, behavioral and societal studies, and computational neurosciences. Individual chapters are focused on crucial topics such as cognitive-behavioral therapy, brain functioning, computational neuroscience, neuro-imaging, and many more. This book explains each section and chapter with utmost clarity to maintain comprehensiveness for every kind of reader. This book covers various classical as well as recent topics from basic to advance level knowledge regarding schizophrenia. The book's contributions regarding its inclusivity of topics, comprehensiveness of language, diversity in knowledge, and focus on the subject will attract all kinds of readers. It can be considered a single comprehensive handy reference book for beginners, including medical students, neuroscientists, researchers, clinicians, and medical practitioners. Cognizance of Schizophrenia will be an invaluable asset for all who are involved in neuroscience research or clinical studies.
    Materialart: Online-Ressource
    Seiten: XII, 312 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811970221
    URL: https://doi.org/10.1007/978-981-19-7022-1
    DOI: 10.1007/978-981-19-7022-1
    DDC: 610.72
    Sprache: Englisch
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  • 28
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    Spray Drying of Vaccines : From Laboratory Research to Industrial Applications (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Drug delivery systems. ; Vaccines Biotechnology. ; Biomaterials. ; Immunotherapy. ; Biomedical Research. ; Drug Delivery. ; Biomaterials-Vaccines. ; Immunotherapy.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 A short introduction to vaccines -- Chapter 2 Thermostability of vaccines -- Chapter 3 Drying technologies for vaccines -- Chapter 4 Aseptic spray drying technology -- Chapter 5 Design of experiment studies and scale-up -- Chapter 6 Applications of spray dried vaccines.-Chapter 7 Conclusions and future perspectives of spray-dried vaccines.
    Kurzfassung: This book addresses the stabilization of vaccine powders by spray drying and provides an overview of the current state of the art on a laboratory and industrial scale. The book aims to familiarize readers with the advances in vaccine spray drying technology to understand its application potential better. In particular, the book addresses the design of aseptic spray dryers, parameters affecting the spray drying process, sterile powder processing, cleaning procedures, and powder filling. In addition, different drying technologies for the production of dry powder vaccines are compared to discuss the unique capabilities of spray drying as a particle technology for vaccines. Special attention is given to research studies on spray-dried vaccines published over the past 30 years, with key findings from laboratory research to clinical trials. Potential applications of spray-dried vaccines and routes of administration are presented in detail. Finally, an outlook is given on how close the aseptic spray-drying of vaccines is to the market and the challenges that need to be overcome to be commercially successful. The book's target audience is academics, researchers, vaccine developers, industry experts, students, and possibly funders, including government agencies, who are active in the field. In addition, the book is a reference source for those involved in the vaccine formulation and biopharmaceutical processing industry.
    Materialart: Online-Ressource
    Seiten: XXIX, 589 p. 243 illus., 176 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031243233
    URL: https://doi.org/10.1007/978-3-031-24323-3
    DOI: 10.1007/978-3-031-24323-3
    DDC: 610.72
    Sprache: Englisch
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  • 29
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    Biomedical Visualisation : Volume 15 ‒ Visualisation in Teaching of Biomedical and Clinical Subjects: Anatomy, Advanced Microscopy and Radiology (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Radiology. ; Medical education. ; Anatomy. ; Biomedical Research. ; Radiology. ; Medical Education. ; Anatomy.
    Beschreibung / Inhaltsverzeichnis: Part I. Microscopy -- Chapter 1. Advances in Microscopy and Its Applications with Special Reference to Fluorescence Microscope: An Overview -- Chapter 2. Visualisation of Host-Pathogen Communication -- Chapter 3. A Review of Pathology and Analysis of Approaches to Easing Kidney Disease Impact: Host-Pathogen Communication and Biomedical Visualization Perspective -- Part II. Radiology and Patient Care -- Chapter 4. The Evolution of Equipment and Technology for Visualising the Larynx and Airway -- Chapter 5. The Impact of Technological Innovation on Dentistry -- Chapter 6. Advanced 3D Visualization and 3D Printing in Radiology -- Chapter 7. 3D Visualisation of the Spine -- Part III. Anatomy Education -- Chapter 8. Visualization in Anatomy Education -- Chapter 9. Visualizing Anatomy in Dental Morphology Education -- Chapter 10. Flashcards: The Preferred Online Game-Based Study Tool Self-Selected by Students to Review Medical Histology Image Content.
    Kurzfassung: This book highlights the integration of science and imaging and demonstrates how we can teach and learn in a much more accessible, innovative, and engaging way using technology. This volume is particularly focused on three main themes: advanced microscopy, anatomy education, and radiology visualisation related to patient care. The chapters pertaining to advanced microscopy convey complex biomedical information by visual means. These chapters provide both an overview on the principles of microscopy and specific applications of microscopy that have led to groundbreaking discoveries. Chapters pertaining to education summarise the recent trends in teaching gross and microscopic anatomy and emphasise the creation and use of novel tools to support student learning. Lastly, the radiological visualisation segment dives into the history of radiographic imaging and highlights the profound effect technology has had on improving patient outcomes. This volume will be of particular interest to many; the scope of this book encompasses medicine, dentistry, allied health professions, biomedical sciences, anatomy and histology education, radiology, and microscopy. Students, researchers, educators, and clinicians will learn something new, be stimulated to ask innovative questions, and be inspired to continue the technological advancements pushing science forward. .
    Materialart: Online-Ressource
    Seiten: XI, 224 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031264627
    Serie: Advances in Experimental Medicine and Biology, 1406
    URL: https://doi.org/10.1007/978-3-031-26462-7
    DOI: 10.1007/978-3-031-26462-7
    DDC: 610.72
    Sprache: Englisch
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  • 30
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    The Renin Angiotensin System in Cancer, Lung, Liver and Infectious Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Human physiology. ; Cancer. ; Cancer Treatment. ; Virology. ; Therapeutics. ; Biomedical Research. ; Human Physiology. ; Cancer Biology. ; Cancer Therapy. ; Virology. ; Therapeutics.
    Beschreibung / Inhaltsverzeichnis: 1. Implications of renin-angiotensin system in health and disease -- 2. Renin angiotensin system and aging -- 3. The interplay of the renin-angiotensin system and solid organ transplantation -- 4. Correlation between renin angiotensin system and infectious disease -- 5. Emerging contributions of endocrine pathophysiology in virus-related infectious disease -- 6. Understanding the renin-angiotensin system in coronavirus disease 2019 -- 7. Metabolomics approach in differentiating RAS responses in ARDS (Acute respiratory distress syndrome) and SAR-CoV-2 -- 8. A Comprehensive review of the impact of the renin angiotensin system in the liver, lung, infectious diseases and cancers -- 9. Application of biosensors for monitoring changes in renin angiotensin system (RAS) in cancers and lung diseases -- 10. Bioinformatics study on renin angiotensin in lung, and liver cancer using plant-based extracts -- 11. Role of renin-angiotensin system in the pathogenesis and progression of non-alcoholic fatty liver -- 12. The classical and nonclassical renin-angiotensin-aldosterone system in liver cirrhosis -- 13. Renin-angiotensin-aldosterone system role in organ fibrosis -- 14. Role of renin angiotensin-aldosterone system in kidney homeostasis -- 15. Renin-angiotensin system in chronic kidney disease: Implications in stroke outcome -- 16. The renin-angiotensin system and cancer -- 17. Renin-angiotensin system and cancer: From laboratory to clinics -- 18. Role of renin-angiotensin system in cancer cachexia -- 19. Renin angiotensin system activity in different cancers: Mechanistic insight and preclinical studies -- 20. The new dimension of the renin-angiotensin system in the hallmarks of cancer -- 21. Renin-angiotensin system in hematological malignancies -- 22. Renin angiotensin system (RAS): The common thread between cancer and heart failure -- 23. Renin-angiotensin system: a potential therapeutic target for colorectal cancer -- 24. Anticancer role of natural phenolic acids by targeting angiotensin-converting enzyme (ACE) -- 25. Angiotensin-(1-7): A Prospective Cancer Therapeutic.
    Kurzfassung: This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.
    Materialart: Online-Ressource
    Seiten: XX, 498 p. 70 illus., 63 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031236211
    Serie: Advances in Biochemistry in Health and Disease, 25
    URL: https://doi.org/10.1007/978-3-031-23621-1
    DOI: 10.1007/978-3-031-23621-1
    DDC: 610.72
    Sprache: Englisch
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  • 31
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    Online-Ressource
    Electromechanobiology of Cartilage and Osteoarthritis : A Tribute to Alan Grodzinsky on his 75th Birthday (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biophysics. ; Biomechanics. ; Immunology. ; Bones. ; Biomedical engineering. ; Biomedical Research. ; Biophysics. ; Biomechanics. ; Osteoimmunology. ; Biomedical Engineering and Bioengineering.
    Beschreibung / Inhaltsverzeichnis: Preface (Brianne K. Connizzo, Lin Han, Robert L. Sah) -- Scientific Impact -- Chapter 1. Aggrecan and Hyaluronan: The infamous Cartilage Polyelectrolytes- Then and Now (Anna Plaas, Meghan Moran, John Sandy, Vincent Hascall) -- Chapter 2. Understanding the Influence of Local Physical Stimuli on Chondrocyte Behavior (Byumsu Ki, Lawrence J. Bonassar) -- Chapter 3. Multiscale In Silico Modeling of Cartilage Injuries (Rami K. Korhonen, Atte S.A. Eskelinen, Gustavo A. Orozco, Amir Esrafilian, Cristina Florea, and Petri Tanska) -- Chapter 4. In Vitro Models and Proteomics in Osteoarthritis Research (Martin Rydén, Patrik Önnerfjord) -- Chapter 5. Nanomechanics of Aggrecan: A New Perspective on Cartilage Biomechanics, Disease and Regeneration (Chao Wang, Elizabeth R. Kahle, Lin Han) -- Chapter 6. Computational Modelling for Managing Pathways to Cartilage Failure (Saeed Miramini, David W. Smith, Bruce S. Gardiner, Lihai Zhang) -- Chapter 7. Gene Delivery to Chondrocytes (Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De la Vega) -- Chapter 8. Mechanical Articular Cartilage Injury Models and Their Relevance in Advancing Therapeutic Strategies (Bodo Kurz, Melanie L Hart, Bernd Rolauffs) -- Chapter 9. Hip Osteoarthritis: Bench to Bedside Perspective (Young-Jo Kim) -- Chapter 10. Harnessing Growth Factor Interactions to Optimize Articular Cartilage Repair (Stephen B. Trippel) -- Personal Tributes -- Index.
    Kurzfassung: This is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.
    Materialart: Online-Ressource
    Seiten: XIV, 173 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031255885
    Serie: Advances in Experimental Medicine and Biology, 1402
    URL: https://doi.org/10.1007/978-3-031-25588-5
    DOI: 10.1007/978-3-031-25588-5
    DDC: 610.72
    Sprache: Englisch
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  • 32
    Online-Ressource
    Online-Ressource
    Tumor Ecosystem : An Ecological View of Cancer Growth and Survival (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Cancer. ; Tumors Immunological aspects. ; Biomedical Research. ; Cancer Biology. ; Cancer Microenvironment. ; Tumour Immunology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Interactions in cancer ecosystem -- Chapter 2: Local niche construction -- Chapter 3: Pre-metastatic niche -- Chapter 4: Emerging concepts in cluster metastasis -- Chapter 5: Neuronal regulation in cancer ecosystem -- Chapter 6: Endocrinal regulation in cancer ecosystem -- Chapter 7: Innate immune system in cancer ecosystem -- Chapter 8: Adaptive immune system in cancer ecosystem -- Chapter 9: Inflammation in cancer ecosystem -- Chapter 10: Metabolic regulation in cancer ecosystem -- Chapter 11: Vascular regulation in cancer ecosystem -- Chapter 12: Microbial interaction in cancer ecosystem -- Chapter 13: Viral interaction in cancer ecosystem -- Chapter 14: Evolution of cancer ecosystem -- Chapter 15: Driving force of cancer ecosystem -- Chapter 16: Modeling, visualizing and subtyping the cancer ecosystem -- Chapter 17: Bio-engineering methods to mimic cancer ecosystem -- Chapter 18: Cancer ecosystem-directed therapeutic strategies.
    Kurzfassung: This book intends to report new concept of onco-spheres in cancer ecosystem. Onco-spheres are defined as where cancer cells (living organisms) dynamically interact with nontumor cellular (other living organisms) and noncellular components (non-living environmental factors) in the ‘host’ internal environment (habitat) to construct a self-sustainable cancer ecosystem, which can be scoped at three different levels: primary/regional, distal and systemic onco-spheres. Cancer cells should be conceived as ‘living organisms’, interacting with cellular or noncellular components in the host internal environment, not only with the local tumor microenvironment (TME) but also constantly communicating with a distant organ niche as well interacting with the host’s nervous, endocrine and immune systems, to construct a self-sustainable ‘biosphere’, as we termed the tumor ecosystem. By looking at the interaction of cancer and host as a unique ecosystem, we will use ecology principles to further delineate the features of the dynamics of the tumor ecosystem. As the pioneer in proposing this concept, we feel that this full-scale overview of the tumor ecosystem is able to inform the readers about this concept, and to pave the way for designing novel therapeutic strategies on actionable targets within tumor ecosystem. The book is likely to be of interest to immunologist, biologist, medical students, researchers and general public who wish to learn more on this new concept of tumor ecosystem, and how this could be applied in many fields of research.
    Materialart: Online-Ressource
    Seiten: XIX, 701 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819911837
    URL: https://doi.org/10.1007/978-981-99-1183-7
    DOI: 10.1007/978-981-99-1183-7
    DDC: 610.72
    Sprache: Englisch
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  • 33
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    Online-Ressource
    Targeting Lysine Demethylases in Cancer and Other Human Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Lysine demethylation in pathogenesis -- Chapter 2. Targeting the LSD1/KDM1 Family of Lysine Demethylases in Cancer and Other Human Diseases -- Chapter 3. KDM2 demethylases as drug targets -- Chapter 4. Role of histone demethylase KDM3 (JMJD1) in transcriptional regulation and cancer progression -- Chapter 5. KDM4 demethylases as drug targets -- Chapter 6. KDM5 lysine demethylases in pathogenesis, from basic science discovery to the clinic -- Chapter 7. Context-dependent functions of lysine demethylases in physiology and disease -- Chapter 8. KDM7 demethylases as drug targets.
    Kurzfassung: This book provides a comprehensive summary of our current knowledge on lysine demethylases, a class of epigenetic regulators. It takes the reader on an exciting journey spanning the past two decades, starting from the initial discovery and characterization of these enzymes and leading up to the development of their small molecule modulators. These modulators have shown promise in clinical trials and hold great potential to improve patient outcomes. The book captures the progress made in this field and highlights the significant advancements that have paved the way for potential therapeutic applications. The book covers a wide range of topics, spanning both basic biology and clinical implications associated with lysine demethylases. It offers a comprehensive historical and conceptual framework for the discovery and characterization of similar epigenetic enzymes or modulators. Chapter one serves as an introductory overview, providing insights into the general characteristics and functions of lysine demethylases. In subsequent chapters, specifically chapters two to eight, each major family of lysine demethylases is individually explored in depth. By providing in-depth insights into the functional aspects of these enzymes, the book allows readers to grasp their significance in regulating cellular processes and influencing pathogenesis. Moreover, the book goes beyond fundamental knowledge and also explores the development of diagnostic and therapeutic strategies related to lysine demethylases. It highlights the potential for utilizing these enzymes as therapeutic targets for the treatment of various diseases, including cancer and infectious diseases. Additionally, the book highlights future directions aimed at further unraveling the roles of lysine demethylases and translating these findings into the clinic.
    Materialart: Online-Ressource
    Seiten: VII, 184 p. 35 illus., 28 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031381768
    Serie: Advances in Experimental Medicine and Biology, 1433
    URL: https://doi.org/10.1007/978-3-031-38176-8
    DOI: 10.1007/978-3-031-38176-8
    DDC: 610.72
    Sprache: Englisch
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  • 34
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    Online-Ressource
    Microscopy Techniques for Biomedical Education and Healthcare Practice : Principles in Light, Fluorescence, Super-Resolution and Digital Microscopy, and Medical Imaging (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical education. ; Materials Microscopy. ; Anatomy. ; Cytology. ; Education Data processing. ; Biomedical Research. ; Medical Education. ; Microscopy. ; Anatomy. ; Cell Biology. ; Computers and Education.
    Beschreibung / Inhaltsverzeichnis: Part I. Advances in Microscopy for Visualization, Education and Healthcare Practice -- Chapter 1. Visualizing the Invisible: Microscopy and How It Affects Our Understanding of Cells and Tissues -- Chapter 2. Morphometric Image Analysis and Its Applications in Biomedicine Using Different Microscopy Modes -- Chapter 3. The Shift in Power from Conventional to Digital and Virtual Microscopy -- Chapter 4. How Visualizations Have Revolutionized Taxonomy: From Macroscopic, to Microscopic, to Genetic -- Chapter 5. Bright New World: Principles of Fluorescence and Applications in Spectroscopy and Microscopy -- Chapter 6. An Introduction to Particle Tracking Techniques with Applications in Biomedical Research -- Chapter 7. An Exploration of the Practice of CT Modalities to Evaluate Anterior Cranial Deformities in Craniosynostosis -- Part II. Anatomical and Cell Biology Education -- Chapter 8. The Use of Biomedical Imaging in Visuospatial Teaching of Anatomy -- Chapter 9. Ultrasound Imaging for Musculoskeletal Research -- Chapter 10. Skill Acquisition in Histology Education.
    Kurzfassung: This edited book has a strong focus on advances in microscopy that straddles research, medical education and clinical practice. These advances include the shift in power from conventional to digital microscopy. The first section of this book covers imaging techniques and morphometric image analysis with its applications in biomedicine using different microscopy modes. Chapters highlight the rich development of fluorescence methods and technologies; particle tracking techniques with applications in biomedical research and nanomedicine; the way in which visualizations have revolutionized taxonomy from gross anatomy to genetics; and the psychology of perception and how it affects our understanding of cells and tissues. The book’s first section concludes by exploring the use of CT modalities to evaluate anterior deformities in craniosynostosis. In the second section of the book, chapters on anatomical and cell biology education explore the history of anatomical models and their use in educational settings. This includes examples in 3D printing and functional human anatomical models that can be created using easily available resources and the use of biomedical imaging in visuospatial teaching of anatomy; the novel use of ultrasound in medical education and practice; and skill acquisition in histology education using a flowchart called a ‘decision tree’. This book will appeal to histologists, microscopists, cell biologists, clinicians and those involved in anatomical education and biomedical visualization, as well as students in those respective fields.
    Materialart: Online-Ressource
    Seiten: XIV, 228 p. 107 illus., 94 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031368509
    Serie: Biomedical Visualization, 2
    URL: https://doi.org/10.1007/978-3-031-36850-9
    DOI: 10.1007/978-3-031-36850-9
    DDC: 610.72
    Sprache: Englisch
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  • 35
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    Online-Ressource
    Hematopoietic Stem Cells : Keystone of Tissue Development and Regenerative Medicine (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Stem cells. ; Developmental biology. ; Biomedical Research. ; Stem Cell Biology. ; Developmental Biology and Stem Cells.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Hematopoietic Stem Cell Development in Mammalian Embryos -- Chapter 2. Hematopoietic Stem Cells and Their Bone Marrow Niches -- Chapter 3. Emerging Roles of Epigenetic Regulators in Maintaining Hematopoietic Stem Cell Homeostasis -- Chapter 4. Metabolism in Hematopoiesis and Its Malignancy -- Chapter 5. The Origin of Clonal Hematopoiesis and Its Implication in Human Diseases -- Chapter 6. Ex vivo Expansion and Homing of Human Cord Blood Hematopoietic Stem Cells -- Chapter 7. N6-methyladenosine RNA Modification in Normal and Malignant Hematopoiesis -- Chapter 8. Immune System Influence on Hematopoietic Stem Cells and Leukemia Development -- Chapter 9. Learning from Zebrafish Hematopoiesis -- Chapter 10. Multi-lineage Differentiation from Hematopoietic Stem Cells -- Chapter 11. Gene Editing in Hematopoietic Stem Cells -- Chapter 12. Aging, Causes and Rejuvenation of Hematopoietic Stem Cells.
    Kurzfassung: This book renders a comprehensive understanding of hematopoietic stem cells (HSCs) from their embryonic development through adult maintenance to aging, in the studies conducted in zebrafish and mammals. Hematopoiesis provides a paradigm for understanding the development, maintenance, regeneration, aging and malignant transformation of mammalian organs. Sitting at the apex of the hematopoiesis hierarchy tree, HSCs orchestrate their proliferation, self-renewal, and differentiation to produce all the blood cell lineages throughout life, which represents the best example for somatic stem cell studies. In this book, key regulatory mechanisms for HSC self-renewal and differentiation are overviewed in an array of fields including epigenetics, metabolism and microenvironment regulation. It also highlights the HSC heterogeneity and clonal dynamics from the recent advanced single-cell technologies. This book elaborates on the research history of HSC studies and reveals how the insights from HSC studies shed light on their clinic application. It presents great value from the bench to the clinic.
    Materialart: Online-Ressource
    Seiten: XV, 210 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819974719
    Serie: Advances in Experimental Medicine and Biology, 1442
    URL: https://doi.org/10.1007/978-981-99-7471-9
    DOI: 10.1007/978-981-99-7471-9
    DDC: 610.72
    Sprache: Englisch
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  • 36
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    Online-Ressource
    Blockchain in Healthcare : From Disruption to Integration (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Blockchains (Databases). ; Medical care. ; Medical Ethics. ; Medical policy. ; Biomedical Research. ; Blockchain. ; Health Care. ; Medical Ethics. ; Health Policy.
    Beschreibung / Inhaltsverzeichnis: 1. Introductory chapter: Early applications and evolution of blockchain implementations in medicine -- 2. Can Blockchain Technology Change Contemporary Medicine As It Is Currently Understood? -- 3. The Current State of Healthcare Information Exchange (HIE) and Proposing a Blockchain HIE Infrastructure -- 4. An amalgamation of blockchain and connected health for combating COVID-19 -- 5. Applications of Blockchain Technology in the COVID-19 Era. 6. Distributed Ledgers and Immunity Passports: The Intersection of Clinical Medicine and Digital Technology -- 7. Digital Identity, Computational Reliabilism, and the Future of IOMT: Epistemic Reasoning and The Role of Blockchain in Removing Human Tampering from Pharmacovigilance Decision Making -- 8. Potential implementations of blockchain technology in patient safety: A high-level overview -- 9. Blockchain in Medical Education -- 10. Blockchain in Education: Linking Competency Assessment with Credentialing -- 11. Optimizing Blockchain Technology in Academic Medicine -- 12. Distributed Research Networks -- 13. Use of Blockchain Technology for Implantable Medical Device Tracking -- 14. Application of Blockchain Technology in Healthcare Supply Chains.
    Kurzfassung: Blockchain technology (BT) is quietly transforming the world, from financial infrastructure, to the internet-of-things, to healthcare applications. With increasing penetration of BT into various areas of our daily lives, the need arises for better awareness and greater knowledge about the capabilities, benefits, risks, and alternatives to distributed ledger applications. It is hoped that current book will be one of the pioneering collections focusing on blockchain implementations in the area of healthcare, with specific aim to present content in an easy-to-understand and readily accessible way for typical end-users of blockchain-based applications. There are important areas within the fabric of modern healthcare that stand to benefit from implementations of BT. These areas include electronic medical records, quality control, patient safety, finance, device tracking, biostamping/biocertification, redundant storage of critical data, health and liability insurance, medication utilization tracking (including opioid and antibiotic misuse), financial transactions, academics/education, asset tokenization, public health and pandemics, healthcare provider credentialing, and many other potential applications. The ultimate goal of the proposed book would be to provide an integrative, easy-to-understand, and comprehensive picture of the current state of blockchain use in healthcare while actively engaging the reader in a forward-looking, exploratory approach toward future developments in this space. To accomplish this goal, an expert panel of contributors has been assembled, featuring scholars from top global universities and think-tanks.
    Materialart: Online-Ressource
    Seiten: VIII, 250 p. 33 illus., 17 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031145919
    Serie: Integrated Science, 10
    URL: https://doi.org/10.1007/978-3-031-14591-9
    DOI: 10.1007/978-3-031-14591-9
    DDC: 610.72
    Sprache: Englisch
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  • 37
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    Introduction to Fluorescence Sensing : Volume 2: Target Recognition and Imaging (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Measurement. ; Measuring instruments. ; Biophysics. ; Biomedical Research. ; Measurement Science and Instrumentation. ; Biophysics.
    Beschreibung / Inhaltsverzeichnis: 1. Principles of molecular recognition -- 2. Theoretical Aspects -- 3. Molecular Recognition Units in Sensor Constructions -- 4. Binding blocks and Interfaces Designed for Sensing -- 5. Probing the properties of continuous media and interfaces -- 6. Detection of Ions and Low-molecular Targets -- 7. Detection of Biological Macromolecules and Recognition of harmful microbes -- 8. Sensing Inside the Living Cells -- 9. Ex-vivo Clinical Diagnostics -- 10. Imaging in vivo -- 11. Theranostics: Combining Targeting, Imaging and Therapy -- 12. Opening new horizons.
    Kurzfassung: Fluorescence is the most popular technique in chemical and biological sensing because of its ultimate sensitivity, high temporal and spatial resolution and versatility that enables imaging within the living cells. It develops rapidly in the directions of constructing new molecular recognition units, new fluorescence reporters and in improving sensitivity of response up to detection of single molecules. Its application areas range from control of industrial processes to environment monitoring and clinical diagnostics. This book provides systematic knowledge of basic principles in design of fluorescence sensing and imaging techniques together with critical analysis of recent developments. Being a guide for students and young researchers, it also addresses professionals involved in active basic and applied research. Making a strong link between education, research and product development, this book discusses prospects for future progress.
    Materialart: Online-Ressource
    Seiten: XXI, 761 p. 290 illus., 260 illus. in color. , online resource.
    Ausgabe: 3rd ed. 2023.
    ISBN: 9783031190896
    URL: https://doi.org/10.1007/978-3-031-19089-6
    DOI: 10.1007/978-3-031-19089-6
    DDC: 610.72
    Sprache: Englisch
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  • 38
    Online-Ressource
    Online-Ressource
    Methodologies of Multi-Omics Data Integration and Data Mining : Techniques and Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Bioinformatics. ; Medical informatics. ; Quantitative research. ; Biomedical Research. ; Bioinformatics. ; Health Informatics. ; Data Analysis and Big Data.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to multi-omics -- Part 1. Omics integration techniques -- Chapter 2. Biomedical applications: the need for multi-omics -- Chapter 3. Omics technologies and big data -- Chapter 4. Multi-omics data mining techniques: algorithms and software -- Part 2. Applications of multi-omics analyses -- Chapter 5. Multi-omics data analysis for cancer research: colorectal cancer, liver cancer and lung cancer -- Chapter 6. Multi-omics data analysis for inflammation disease research: correlation analysis, causal analysis and network analysis -- Chapter 7. Microbiome data analysis and interpretation: correlation inferences and dynamic pattern discovery -- Chapter 8. Current progress of bioinformatics for human health.
    Kurzfassung: This book features multi-omics big-data integration and data-mining techniques. In the omics age, paramount of multi-omics data from various sources is the new challenge we are facing, but it also provides clues for several biomedical or clinical applications. This book focuses on data integration and data mining methods for multi-omics research, which explains in detail and with supportive examples the “What”, “Why” and “How” of the topic. The contents are organized into eight chapters, out of which one is for the introduction, followed by four chapters dedicated for omics integration techniques focusing on several omics data resources and data-mining methods, and three chapters dedicated for applications of multi-omics analyses with application being demonstrated by several data mining methods. This book is an attempt to bridge the gap between the biomedical multi-omics big data and the data-mining techniques for the best practice of contemporary bioinformatics and the in-depth insights for the biomedical questions. It would be of interests for the researchers and practitioners who want to conduct the multi-omics studies in cancer, inflammation disease, and microbiome researches.
    Materialart: Online-Ressource
    Seiten: XI, 167 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811982101
    Serie: Translational Bioinformatics, 19
    URL: https://doi.org/10.1007/978-981-19-8210-1
    DOI: 10.1007/978-981-19-8210-1
    DDC: 610.72
    Sprache: Englisch
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  • 39
    Online-Ressource
    Online-Ressource
    A Guide to Responsible Research (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Clinical medicine Research. ; Medical sciences. ; Drug development. ; Bioethics. ; Medical Ethics. ; Biomedical Research. ; Clinical Research. ; Preclinical Research. ; Bioethics. ; Medical Ethics.
    Beschreibung / Inhaltsverzeichnis: Chap 1. Research Environment -- Chap 2. Training, Supervision and Mentoring -- Chap 3. Research Procedures -- Chap 4. Safeguards -- Chap 5. Data Practices and Management -- Chap 6. Collaborative Working -- Chap 7. Publication and Dissemination -- Chap 8. Reviewing, Evaluating and Editing -- Chap 9. How to deal with allegations of misconduct.
    Kurzfassung: This Open Access book is a guide to good, responsible research at each step of the process of research discovery, so that a researcher at the beginning of a scientific career has a clear pathway to doing good research and producing reliable results. The textbook will give context to the practices described in the European Code of Conduct for Research Integrity, guided by the fundamental principles or research integrity – reliability, honesty, respect, and accountability. The chapters in the book follow the good practices outlined in the Code, give practical advice and address basic principles. In this way, the book is applicable to different research fields. It directs readers to various sources for further and updated information, particularly drawing from the resources available at The Embassy of Good Science, the European platform for research integrity and ethics.
    Materialart: Online-Ressource
    Seiten: XIII, 135 p. 13 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031224126
    Serie: Collaborative Bioethics, 1
    URL: https://doi.org/10.1007/978-3-031-22412-6
    DOI: 10.1007/978-3-031-22412-6
    DDC: 610.72
    Sprache: Englisch
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  • 40
    Online-Ressource
    Online-Ressource
    Biological and Clinical Landscape of Meningiomas (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction and History of Meningiomas -- Chapter 2. Clinical Presentation and Prognosis -- Chapter 3. Imaging Characteristics of Meningiomas -- Chapter 4. Histopathology of Meningiomas -- Chapter 5. Skull Base Meningiomas -- Chapter 6. Spinal Meningiomas -- Chapter 7. Surgical Therapies -- Chapter 8. Radiation Therapies -- Chapter 9. Illustrative Cases -- Chapter 10. Advances in CNS Tumor Classification -- Chapter 11. Genomic Landscape -- Chapter 12. Radiation-Induced Meningiomas -- Chapter 13. Meningioma Predisposing Syndromes -- Chapter 14. Epigentic Landscape -- Chapter 15. Immune Profile -- Chapter 16. PDX Models/Mouse Models/Cell Lines -- Chapter 17. Novel Medical Therapies -- Chapter 18. Quality of Life in Menigioma Patients -- Chapter 19. Illustrative Cases: Revisited with Adjuvant Molecular Data -- Chapter 20. Future Directions in Management.
    Kurzfassung: "Meningiomas are tumors that originate from the arachnoidal cap cells of the leptomeninges. With an incidence rate of 8.36 per 100, 000 population, they are the most common primary central nervous system (CNS) tumors, accounting for a third of all cases. The World Health Organization (WHO) classification has traditionally categorized meningiomas into 15 different histopathological subtypes and three clinical grades. Tumors are classified as WHO grades 1, 2 or 3 based largely on histopathological features such as mitotic activity, presence of brain invasion, and other atypical features. However, there is increasing recognition of the limitations of histopathology including but not limited to: confounding factors such as sampling bias in a heterogeneous tumor, and technical factors related to the experience of the grading pathologist. Even with careful histologic grading, there remains significant variability in recurrence rates within each tumor grade. As more studies have uncovered the molecular features of meningiomas, novel biological alterations have helped refine classification schemes that more accurately reflect patient outcomes. This book reviews the current state of knowledge on the genomic and epigenomic landscape of meningiomas in order to identify the roles of genomic aberrations on diagnosis, prognosis, and treatment of meningiomas in addition to mainstays of surgical management, radiation therapy, and potential novel chemotherapies. Written by a team of world-renowned experts in neurosurgery, neuropathology, radiology, and radiation-oncology, this book is the definitive resource on meningioma management and investigation for both clinicians and scientists alike.".
    Materialart: Online-Ressource
    Seiten: XVII, 255 p. 55 illus., 33 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031297502
    Serie: Advances in Experimental Medicine and Biology, 1416
    URL: https://doi.org/10.1007/978-3-031-29750-2
    DOI: 10.1007/978-3-031-29750-2
    DDC: 610.72
    Sprache: Englisch
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  • 41
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    Online-Ressource
    Quantitative Ultrasound in Soft Tissues (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biomedical engineering. ; Biophysics. ; Medical physics. ; Signal processing. ; Bioinformatics. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Biophysics. ; Medical Physics. ; Signal, Speech and Image Processing . ; Bioinformatics.
    Beschreibung / Inhaltsverzeichnis: Preface -- Part I: Backscatter Coefficient methods -- Chapter 1. Quantitative Ultrasound: an Emerging Technology for Detecting, Diagnosing, Imaging, Evaluating, and Monitoring Disease (Ernie Feleppa) -- Chapter 2. Quantitative Ultrasound: Scattering theory (Michael Oelze) -- Chapter 3. Quantitative Ultrasound: Experimental implementation (Michael Oelze) -- Chapter 4. Extracting Quantitative Ultrasonic Parameters from the Backscatter Coefficient (Aiguo Han) -- Part II: Attenuation Estimation Methods -- Chapter 5. Attenuation Compensation and Estimation (Timothy Bigelow and Yassin Labyed) -- Chapter 6. Recent advances in attenuation estimation (Ivan Rosado Mendez) -- Part III: Envelope Statistics Methods -- Chapter 7. Review of envelope statistics models for quantitative ultrasound imaging and tissue characterization (Francois Destrempes and Guy Cloutier) -- Chapter 8. Information entropy and its applications (Po-Hsaing Tsui) -- Part IV: Ultrasound Computed Tomography -- Chapter 9. Ultrasound Tomography (Nicole Ruiter, Torsten Hopp, Michael Zapf and Hartmut Gemmek) -- Chapter 10. Full Wave Inversion and Inverse Scattering in Ultrasound Tomography/Volography (James Wiskin) -- Chapter 11. Clinical Importance of 3D Volography in Breast Imaging (John Klock) -- Part V: Acoustic microcopy -- Chapter 12. Acoustic Microscopy (Yoshifumi Saijo) -- Chapter 13. Advanced Topics in Quantitative Acoustic Microscopy (Cameron Hoerig and Jonathan Mamou) -- Part VI: Phantoms for Quantitative Ultrasound -- Chapter 14. Phantoms for Quantitative Ultrasound (Tim Stiles) -- Index.
    Kurzfassung: Quantitative ultrasound (QUS) continues to mature as a research field and is primed to make a swift transition to routine preclinical and clinical applications. This book will serve two main purposes: Advanced education in QUS by providing a complete and thorough review of all theoretical, physical, and engineering aspects of QUS. Review of recent development of QUS by lead contributors in the research field. This 2nd edition will focus on 6 modern research topics related to quantitative ultrasound of soft tissues: Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc. Attenuation estimation for tissue characterization and improving spectral based methods Envelope statistics analysis as a means of quantifying and imaging tissue properties. Ultrasound computed tomography for preclinical and clinical imaging. Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution. Phantoms for quantitative ultrasound.
    Materialart: Online-Ressource
    Seiten: X, 307 p. 1 illus. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031219870
    Serie: Advances in Experimental Medicine and Biology, 1403
    URL: https://doi.org/10.1007/978-3-031-21987-0
    DOI: 10.1007/978-3-031-21987-0
    DDC: 610.72
    Sprache: Englisch
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  • 42
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    Online-Ressource
    Extracellular Vesicles in Cardiovascular and Metabolic Diseases (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Cytology. ; Biological transport. ; Cell membranes. ; Biomedical Research. ; Translational Research. ; Cell Biology. ; Membrane Trafficking.
    Beschreibung / Inhaltsverzeichnis: Section I. Extraction Methods -- Chapter 1. Updated Methods of Extracellular Vesicles Isolation -- Section II. Extracellular Vesicles in Cardiovascular Disease -- Chapter 2. Extracellular Vesicles and Pathological Cardiac Hypertrophy -- Chapter 3. Extracellular Vesicles and Cardiac Aging -- Chapter 4. Extracellular Vesicles and Ischemic Cardiovascular Diseases -- Chapter 5. Extracellular Vesicles and Hypertension -- Chapter 6. Extracellular Vesicles and Coronary Artery Disease -- Chapter 7. Extracellular Vesicles and Vascular Inflammation -- Chapter 8. Extracellular Vesicles and Muscle Atrophy Treatment -- Section III. Extracellular Vesicles in Metabolic Diseases -- Chapter 9. Extracellular Vesicles and Fatty Liver -- Chapter 10. Extracellular Vesicles and Obesity -- Chapter 11. Extracellular Vesicles in Bone Remodeling and Osteoporosis -- Section IV. Therapeutic Implications -- Chapter 12. Diagnosis of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 13. Therapeutics of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 14. Gene Therapy of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Section V. Future Prospects -- Chapter 15. Prospective Advances of Extracellular Vesicles Investigation in Cardiovascular and Metabolic Research -- Chapter 16. Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 17. Extracellular Vesicle Release from Platelets and their Contributions to Thrombosis.
    Kurzfassung: This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
    Materialart: Online-Ressource
    Seiten: VIII, 275 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819914432
    Serie: Advances in Experimental Medicine and Biology, 1418
    URL: https://doi.org/10.1007/978-981-99-1443-2
    DOI: 10.1007/978-981-99-1443-2
    DDC: 610.72
    Sprache: Englisch
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  • 43
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    Online-Ressource
    Graphic Medicine, Humanizing Healthcare and Novel Approaches in Anatomical Education (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical education. ; Anatomy. ; Education Data processing. ; Biomedical Research. ; Medical Education. ; Anatomy. ; Computers and Education.
    Beschreibung / Inhaltsverzeichnis: Part I. History of Medical Illustration, Graphic Medicine, Humanizing Healthcare and Equitable Visualizations -- Chapter 1. Drawn Together: Merging the Worlds of Health and Comics Through Graphic Medicine -- Chapter 2. Medical Graphics and Graphic Medicine -- Chapter 3. Decolonising Visual Narratives in Global Health: The Case for Equitable and Ethical Imagery Use -- Chapter 4. Medical Illustration in Anatomy -- Chapter 5. Valuing Creativity in Biomedical Science Education: A Reflective Narrative -- Chapter 6. Biomedical Visualization in Embryology Education: A Scoping Review -- Chapter 7. A Framework for the Design, Production, and Evaluation of Scientific Visualizations -- Part II. Anatomical and Cell Biology Education -- Chapter 8. Palpation: The Art of Felt Anatomy -- Chapter 9. Teaching Histology with Analogies -- Chapter 10. Using the Hands for Learning Anatomy -- Chapter 11. Corporeal Pedagogy: Visualizing Anatomy Through Art, Archaeology and Medicine.
    Kurzfassung: This book contains subjects by authors with a fresh, exciting and extensive focus within the medical humanities, offering the reader chapters which include the history of medical illustration, Graphic Medicine as a vehicle for the expression of humanistic dimensions of healthcare, equitable and ethical medical illustrations, as well as novel, art-based approaches in anatomical education. Authors consider the role of visual narratives in medical and scientific illustration, the unique affordances of the comics medium, the history of comics as a form of medical and scientific visualization, and the role of comics as didactic tools and as vehicles for the expression of the humanistic dimensions of healthcare. A chapter considers ethical and equitable implications in global healthcare practice, and highlights the work currently being undertaken to address inappropriate and problematic depictions of people in global health visualizations. This will inform the reader of emerging and current thinking about visual communication and the use of images in the public domain, as well as in the healthcare and education sectors. Novel approaches in anatomical education include the benefits of three-dimensional anatomy models made of felt, visual analogies as a method to enhance students’ learning of histology, the use of the hands for learning anatomy, and visualizing anatomy through art, archaeology and medicine. This book will appeal to readers who have an interest in the medical humanities, Graphic Medicine, and ethical medical and anatomical illustrations. These include academic and non-academic readers, medical students, medical educators, clinicians, health-care workers, as well as policy makers.
    Materialart: Online-Ressource
    Seiten: XIV, 249 p. 88 illus., 81 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031390357
    Serie: Biomedical Visualization, 3
    URL: https://doi.org/10.1007/978-3-031-39035-7
    DOI: 10.1007/978-3-031-39035-7
    DDC: 610.72
    Sprache: Englisch
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  • 44
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    Online-Ressource
    Pulmonomics: Omics Approaches for Understanding Pulmonary Diseases (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Genetics. ; Bioinformatics. ; Biomedical Research. ; Genetics and Genomics. ; Bioinformatics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1_Introduction to Pulmonary Diseases and OMICS approaches -- Chapter 2_Obstructive Pulmonary Diseases -- Chapter 3_COPD (Chronic Obstructive Pulmonar Diseases) -- Chapter 4_ Asthma -- Chapter 5_Other obstructive airway diseases like Bronchiectases, Focal airway narrowing -- Chapter 6_Restrictive Pulmonary Diseases (Common qualities and features with examples) -- Chapter 7_Interstitial Pulmonary fibrosis (IPF) -- Chapter 8_Sarcoidosis -- Chapter 9_ Other restrictive airway diseases like pneumonitis, pleural thickening -- Chapter 10_Vascular Diseases -- Chapter 11_Pulmonary hypertension -- Chapter 12_Pulmonary edema -- Chapter 13_ Other vascular diseases like Pulmonary Edema, Cor Pulmonale -- Chapter 14_Infectious Diseases -- Chapter 15_Tuberculosis -- Chapter 16_Cystic fibrosis -- Chapter 17_Pneumonia, COVID-19 and others -- Chapter 18_Neoplastic Diseases/Lung Cancer.
    Kurzfassung: This book comprehensively reviews various omics approaches like genomics, proteomics, transcriptomics, and metabolomics for understanding pulmonary disease at molecular and systems levels. The initial chapters present the pathogenesis of major pulmonary diseases, namely, obstructive diseases, restrictive diseases, vascular diseases, infectious diseases, and neoplastic carcinoma. The book chapters provide current information about the role of the microbiome and applications of medical imaging, bioinformatics tools, and databases for diagnosis and designing treatment strategies against complex lung diseases. Further, the book discusses omics technologies to identify biomarkers for the early diagnosis and prognosis of pulmonary diseases. Finally, the book elucidates the multi-omics approaches and data integration using mathematical modeling for insights into the disease etiology towards improving the prognostics and predictive accuracy of disease phenotypes.
    Materialart: Online-Ressource
    Seiten: XIII, 405 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819935055
    URL: https://doi.org/10.1007/978-981-99-3505-5
    DOI: 10.1007/978-981-99-3505-5
    DDC: 610.72
    Sprache: Englisch
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  • 45
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    Online-Ressource
    Evaluating Participatory Mapping Software (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Cartography. ; Software engineering. ; Application software. ; Geographical Information System. ; Cartography. ; Software Engineering. ; Computer and Information Systems Applications.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Introduction to Participatory Mapping Software and Evaluation -- Chapter 2: Collector for ArcGIS -- Chapter 3: Field Papers -- Chapter 4: GeoODK -- Chapter 5: Maptionnaire -- Chapter 6: KoBoToolbox -- Chapter 7: SeaSketch -- Chapter 8: Sapelli -- Chapter 9: Survey123 -- Chapter 10: Ushahidi -- Chapter 11: Mapeo -- Chapter 12: Terrastories -- Chapter 13: Portable OpenStreetMap -- Chapter 14: MapBox -- Chapter 15: Trends and Conclusions.
    Kurzfassung: This volume provides a framework for evaluating geospatial software for participatory mapping. The evaluation is based on ten key indicators: ethics, cost, technical level, inclusiveness, data accuracy, data privacy, analytical capacity, visualization capacity, openness, and accessibility (i.e., mobile friendly or offline capabilities). Each application is evaluated by a user and cross analyzed with specific case studies of the software’s real-world application. This framework does not discriminate against assessing volunteered geographic information (VGI) applications, as a form of participatory mapping, in circumstances that its application is spearheaded by underrepresented groups with the intent to empower and spark political or behavioral change within formal and informal institutions. Each chapter follows a strict template to ensure that the information within the volume can be updated periodically to match the ever-changing technological environment. The book covers twelve different mapping applications with the goal of creating a comparative evaluation framework that can be easily interpreted by convening institutions and novice users. This will also help identify gaps in software for participatory mapping which will help to inform application development in the future and updates to current geospatial software.
    Materialart: Online-Ressource
    Seiten: XXV, 265 p. 69 illus., 64 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031195945
    URL: https://doi.org/10.1007/978-3-031-19594-5
    DOI: 10.1007/978-3-031-19594-5
    DDC: 910.285
    Sprache: Englisch
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  • 46
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    Spatial Observation of Giant Panda Habitat : Techniques and Methods (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Geographic information systems. ; Human ecology Study and teaching. ; Environment. ; Geographical Information System. ; Environmental Studies. ; Environmental Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Natural heritage sites and space observation -- Chapter 2. Space monitoring technology and method of natural heritage sites -- Chapter 3. Technology and method of fine information extraction of animal habitat elements -- Chapter 4. Analysis of changes of key environmental parameters of land surface characteristics of giant panda habitat -- Chapter 5. Spatial observation and assessment of ecological environment change of giant panda habitat -- Chapter 6. The evaluation model of long-term monitoring and restoration of ecological environment by remote sensing after earthquake -- Chapter 7. Fine-Scale Evaluation of Giant Panda Habitats and Countermeasures against the Future Impacts of Climate Change -- Chapter 8. Suggestions for sustainable development of giant panda habitat.
    Kurzfassung: This book evaluates the past, present, and future habitat suitability of giant pandas based on spatial observation technology involving optical remote sensing, microwave remote sensing, and LiDAR to discover the mysterious ecological environment of giant panda habitat. Considering the problems faced by the world natural heritage site protection, it takes the world natural heritage site “Sichuan Giant Panda Sanctuaries – Wolong, Mt Siguniang and Jiajin Mountains” as the research area, exemplifies systematically the various techniques and methodologies of spatial information technology for monitoring, evaluation, and prediction of rare and endangered species habitats, and provides scientific suggestions for sustainable development of giant panda habitat based on a series of comprehensive case analysis at Wolong national nature reserve and Ya'an prefecture, Sichuan province, China. The book serves both as a textbook in the field of natural heritage protection, remote sensing, and GIS application, as well as a reference for managing natural heritage sites.
    Materialart: Online-Ressource
    Seiten: XVII, 378 p. 167 illus., 106 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811987946
    URL: https://doi.org/10.1007/978-981-19-8794-6
    DOI: 10.1007/978-981-19-8794-6
    DDC: 910.285
    Sprache: Englisch
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  • 47
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    Dynamic and Precise Engineering Surveying (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Geographic information systems. ; Surveying. ; Cartography. ; Geotechnical engineering. ; Geographical Information System. ; Surveying. ; Cartography. ; Geotechnical Engineering and Applied Earth Sciences.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Structural state surveying for transportation infrastructure -- Dynamic surveying in autonomous driving -- Indoor and underground space measurement -- UAV 3D measurement -- Coastal zone survey -- Outlook. .
    Kurzfassung: Driven by the increasingly expanding needs of infrastructure construction, operation and maintenance, as well as the rapid developments of intelligent sensing and information technology, precise engineering surveying has been transformed from static, discrete, and manual into dynamic, continuous, and intelligent ways. This transformation leads to an advanced multidisciplinary field, dynamic and precise engineering surveying, on which the author has worked for over two decades. This book systematically summarizes the fundamentals, methods, and applications in dynamic and precise engineering surveying. The contents mainly include two parts: the first part introduces principles and methods of dynamic and precise engineering surveying; the second part presents representative applications in which innovative methods and advanced equipment are applied in the construction, operation and maintenance of mega and complex infrastructures. Readers engaged in surveying and mapping, civil engineering, water conservancy engineering, railway engineering, electronic information, and computer science, including undergraduates, graduates, researchers and engineers, will find it an informative reference.
    Materialart: Online-Ressource
    Seiten: XXVIII, 498 p. 394 illus., 352 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819959426
    URL: https://doi.org/10.1007/978-981-99-5942-6
    DOI: 10.1007/978-981-99-5942-6
    DDC: 910.285
    Sprache: Englisch
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  • 48
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    Applied Geography and Geoinformatics for Sustainable Development : Proceedings of ICGGS 2022 (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Environmental geography. ; Sustainability. ; Geographical Information System. ; Integrated Geography. ; Sustainability.
    Beschreibung / Inhaltsverzeichnis: Chapter1. Flood Susceptibility Mapping Using a Frequency Ratio Model: A Case Study of Chai Nat Province, Thailand -- Chapter2. Influence of Hydrosphere Material Knowledge on the Attitude of High School Students in Conducting Water Conservation in Brebes Regency, Indonesia -- Chapter3. Optimizing multi-reservoir systems with the aid of genetic algorithm: Mahanadi reservoir project complex,Chhattisgarh -- Chapter4. Monitoring of Morphological Change in Lam Phachi River Using Geo-Informatics System -- Chapter5. Developing Scenario of Plastic Waste Leakage in Jakarta Hydrology Environment using Seasonal Data Condition and Socio-Economic Aspects -- Chapter6. Measurement of PM10, PM2.5, NO2, and SO2 Using Sensors -- Chapter7. Encoding Social Media Wording Indexes to Analyse PM2.5 Problem Perception -- Chapter8. Noise mapping of different zones in an urban area during Deepawali festival -- Chapter9. Digital Twins in farming with the implementation of agricultural technologies -- Chapter10. A cross-comparison between Rice Crop Monitoring System: GISTDA and International Asian Harvest mOnitoring system for Rice (INAHOR): JAXA -- Chapter11. Evaluation MODIS and Sentinel-2 data for detecting crop residue burned area -- Chapter12. Machine Learning Approach with Environmental Pollution and Geospatial Information for Mapping Poverty in Thailand -- Chapter13. Integration of Machine Learning Algorithms and Time-series Satellite images on Land Use/Land Cover Mapping with Google Earth Engine -- Chapter14. Sugarcane and Cassava Classification using Machine Learning Approach based on Multi-temporal Remote Sensing Data Analysis -- Chapter15. Google Earth Engine algorithm for Evaluating the Performance of Landsat OLI-8 and Sentinel-2 in Mangrove Monitoring -- Chapter16. Estimation of Aboveground Biomass and Carbon Stock using Remote Sensing Data for Sakaerat Environmental Research Station, Thailand -- Chapter17. Determination of Land Suitability for Oil Palm with Multi-Dimension Decision Support using Analytic Network Process (ANP) in Southern Thailand -- Chapter18. Land use change and ecosystem service variations in Huai Luang River basin, Udon Thani province, Thailand -- Chapter19. The Ability to Access Attractions for the Elderly from Public Transport in Bangkok Metropolis.
    Kurzfassung: This volume presents the proceedings of the 2nd International Conference of Geography and Geoinformatics for Sustainable Development (ICGGS), held in Phuket, Thailand, April 7-8, 2022. The collection focuses on the importance of spatial thinking and planning by applying geography concepts and geospatial technology innovations in solving global problems such as environmental degradation, urban pollution, and climate change. The proceedings consist of case studies on wide-ranging spatial issues in developing countries, addressing challenges in mainstreaming sustainable development paradigms into their economies to improve natural resource and environmental management. One of the main goals of the volume is to share and exchange different points of view regarding global, regional, and local spatial issues and how to use geography and geoinformatics for building resilience in multiple sectors, e.g., water, ecosystems, agriculture, and health. It offers the opportunity to learn about how geospatial concepts and technologies can contribute to environmental sustainability, while advancing education and research related to geography and geoinformatics. It will be a useful resource for students and researchers to initiate research ideas related to geospatial topics in regional and local scales.
    Materialart: Online-Ressource
    Seiten: VI, 260 p. 119 illus., 111 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031162176
    Serie: Springer Geography,
    URL: https://doi.org/10.1007/978-3-031-16217-6
    DOI: 10.1007/978-3-031-16217-6
    DDC: 910.285
    Sprache: Englisch
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  • 49
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    Exploring the Earth with QGIS : A Guide to Using Satellite Imagery at Its Full Potential (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Geographic information systems. ; Open source software. ; Earth sciences. ; Geographical Information System. ; Open Source. ; Earth Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Introduction to QGIS -- Chapter 2: Plugins -- Chapter 3: Data Acquisition -- Chapter 4: Data Preprocessing -- Chapter 5: Data Management -- Chapter 6: Data Visualization -- Chapter 7: Data Analysis -- Chapter 8: Integration of Remote Sensing Data with Other Spatial Datasets -- Chapter 9: Integration of QGIS with Google Earth Engine (GEE) -- Chapter 10: Case Studies and Examples of Earth Remote Sensing Applications Using QGIS.
    Kurzfassung: With the rapid advancements in satellite technology, earth remote sensing has become an indispensable tool for a wide range of applications, from environmental monitoring to disaster management. However, the vast amount of data generated by these satellites can be overwhelming for many researchers and practitioners who lack the necessary skills and tools to process and analyze it. This is where QGIS comes in. QGIS is a powerful, open-source Geographic Information System (GIS) software that has been extensively used in the field of earth remote sensing. It provides a user-friendly platform for processing, analyzing, and visualizing satellite imagery, enabling users to unlock the full potential of earth remote sensing data. The purpose of this book is to help researchers and practitioners who lack the necessary skills and tools to process and analyze satellite imagery using QGIS. There are several books that cover the use of QGIS for earth remote sensing, but most of them are either too technical or too general. This book fills this gap by providing a comprehensive and user-friendly guide to using QGIS for earth remote sensing applications. It includes a range of real-world case studies that demonstrate the power and versatility of QGIS for solving complex problems in earth remote sensing. This will provide readers with practical examples of how to use QGIS for earth remote sensing and inspire them to explore new applications and possibilities. The book is intended for GIS professionals, students (undergraduate and graduate), and researchers who are interested in using QGIS for earth remote sensing applications. It will be particularly useful for those who are new to QGIS or who want to expand their knowledge of the software for remote sensing purposes.
    Materialart: Online-Ressource
    Seiten: XIX, 232 p. 300 illus., 283 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031460425
    Serie: Springer Remote Sensing/Photogrammetry,
    URL: https://doi.org/10.1007/978-3-031-46042-5
    DOI: 10.1007/978-3-031-46042-5
    DDC: 910.285
    Sprache: Englisch
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  • 50
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    Optimal Surface Fitting of Point Clouds Using Local Refinement : Application to GIS Data (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Mathematics Data processing. ; Mathematical statistics Data processing. ; Geographical Information System. ; Computational Mathematics and Numerical Analysis. ; Statistics and Computing.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Locally Refined Splines -- Adaptive surface Fitting with Local Refinement: LR B-spline Surfaces -- A Statistical Criterion to Judge the Goodness of Fit of LR B-splines Surface Approximation -- LR B-splines for Representation of Terrain and Seabed: Data Fusion, Outliers, and Voids -- LR B-spline Surfaces and Volumes for Deformation Analysis of Terrain Data -- Conclusion.
    Kurzfassung: This open access book provides insights into the novel Locally Refined B-spline (LR B-spline) surface format, which is suited for representing terrain and seabed data in a compact way. It provides an alternative to the well know raster and triangulated surface representations. An LR B-spline surface has an overall smooth behavior and allows the modeling of local details with only a limited growth in data volume. In regions where many data points belong to the same smooth area, LR B-splines allow a very lean representation of the shape by locally adapting the resolution of the spline space to the size and local shape variations of the region. The iterative method can be modified to improve the accuracy in particular domains of a point cloud. The use of statistical information criterion can help determining the optimal threshold, the number of iterations to perform as well as some parameters of the underlying mathematical functions (degree of the splines, parameter representation). The resulting surfaces are well suited for analysis and computing secondary information such as contour curves and minimum and maximum points. Also deformation analysis are potential applications of fitting point clouds with LR B-splines.
    Materialart: Online-Ressource
    Seiten: XIX, 111 p. 61 illus., 59 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031169540
    Serie: SpringerBriefs in Earth System Sciences,
    URL: https://doi.org/10.1007/978-3-031-16954-0
    DOI: 10.1007/978-3-031-16954-0
    DDC: 910.285
    Sprache: Englisch
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  • 51
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    Monitoring of Desert Locust in Africa and Asia (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Geographic information systems. ; Agriculture. ; Environmental sciences Social aspects. ; Geographical Information System. ; Agriculture. ; Environmental Social Sciences.
    Beschreibung / Inhaltsverzeichnis: Foreword -- Preface -- Chapter 1 Introduction -- Chapter 2 Desert Locust Breeding Area and Migration Path in Africa and Asia -- Chapter 3 Monitoring of Desert Locusts in East Africa -- Chpater 4 Monitoring of Desert Locusts in West and South Asia -- Chapter 5 Remote Sensing Monitoring System of Desert Locust and its Application -- References.
    Kurzfassung: This book deals with the topic on remote sensing monitoring of desert locust in Africa and Asia. Remote sensing monitoring of the occurrence and damage of desert locust is conducted by integrating cutting-edge technologies and methods in cross-disciplinary fields in remote sensing science, geographic information science, agronomy, plant protection, agricultural meteorology, mathematics, and computer science. The main contents include spatio-temporal data analysis and processing, desert locust breeding areas monitoring, pest migration path analysis and damage monitoring. Moreover, a desert locust remote sensing monitoring system is constructed and applied in the region of Africa and Asia countries. This book not only provides technical reference for remote sensing monitoring and application of desert locust but also serves as a research reference for scholars and graduate students engaged in agricultural remote sensing, agricultural information technology, plant protection and other related field. It will help to improve remote sensing monitoring and application of desert locust.
    Materialart: Online-Ressource
    Seiten: XIV, 126 p. 116 illus., 113 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811972386
    URL: https://doi.org/10.1007/978-981-19-7238-6
    DOI: 10.1007/978-981-19-7238-6
    DDC: 910.285
    Sprache: Englisch
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  • 52
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    Online-Ressource
    Geographic Information Systems in Urban Planning and Management (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Geographic information systems. ; Geography. ; Human geography. ; Environmental sciences Social aspects. ; Geographical Information System. ; Regional Geography. ; Human Geography. ; Environmental Social Sciences.
    Beschreibung / Inhaltsverzeichnis: Introduction of Geographic Information System -- Referencing and Coordinate Systems in GIS -- GIS Data Models -- Data Input in GIS -- Data Visualization and Output -- Spatial Data Analysis -- Non-spatial Data Management -- Applications of GIS in Urban Policy/Planning/Management -- Monitoring and Modelling of Urban Land Use Changes -- Simulating Future Urban Growth using Cellular Automata-Markov Chain Models -- Identification of Potential Sites for Housing Development Using GIS Based Multi-Criteria Evaluation Technique -- Urban Green Space Analysis and Potential Site Selection for Green Space Expansion -- A Multi-Criteria Decision Making for Alternative Landfill Site Selections Using Fuzzy TOPSIS Approach -- Urban Flood Susceptibility Modelling of Srinagar using Novel Fuzzy Multi-Layer Perceptron Neural Network (Fuzzy MLPNN) -- Assessment, Mapping and prediction of Urban Heat Island. .
    Kurzfassung: Geographic Information Systems (GIS) play a pivotal role in the field of urban planning and management and provide better solutions for numerous urban problems. With GIS, one has the ability to better understand existing requirements of a city and its design to fulfill those needs. This book contributes to developing scientific knowledge based on geospatial technologies among planners, researchers, scientists, professionals, students, and laymen and providing them with better understanding for urban planning and management at various levels. The book manifests the importance of GIS in better understanding of current urban challenges and provides new insights on how to apply GIS in urban planning. It also encourages the various stakeholders of society to participate in the decision-making process and assists planners and authorities to formulate suitable plans for sustainable urban growth of a region. The book is divided into two parts. The first part describes the fundamental concepts of GIS and also deals with the advanced techniques of spatial planning. The second part addresses real-world case studies using various applications of GIS. The case studies include urban land-use changes, simulation of future urban growth, urban heat island, alternate landfill site selection and urban flood susceptibility mapping, among others. This book shows how to integrate GIS with remote sensing, geostatistics, artificial intelligence-machine learning techniques, and other cutting-edge technologies. Readers find this book to be an invaluable resource for understanding and solving problems relating to sustainable urban planning and management.
    Materialart: Online-Ressource
    Seiten: XVII, 252 p. 115 illus., 51 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811978555
    Serie: Advances in Geographical and Environmental Sciences,
    URL: https://doi.org/10.1007/978-981-19-7855-5
    DOI: 10.1007/978-981-19-7855-5
    DDC: 910.285
    Sprache: Englisch
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  • 53
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    Online-Ressource
    Real Estate Market of Ukraine : Practical Aspects and Trends (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Geographic information systems. ; Real estate management. ; Geographical Information System. ; Real Estate Management.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. General State of the Real Estate Market in Ukraine -- Chapter 2. Real Estate Market. Trends and Developments -- Chapter 3. Practical Aspects. Development of a Method of Modeling the most attractive location of a Real Estate object -- Chapter 4. Determination of the Optimal location of the Real Estate object -- Chapter 5. Factors of Influence on the Real Estate Market -- Chapter 6. Prospects for the Development of the Real Estate Market in Ukraine -- Chapter 7. The Situation on the Real Estate Market because of Russia's War against Ukraine. .
    Kurzfassung: This book shows examples of basic approaches in real estate market analysis. Of value is the method of modeling the most attractive location of real estate, which is illustrated by a specific example. The authors give examples of real estate market research using GIS. The book analyzes the trends and prospects of real estate market development both in the pre-war and in the post-war period in Ukraine. It provides factors, trends, and development of the real estate market-directed investments. This book is useful to investors, real estate appraisers, real estate market researchers, GIS specialists, developers, researchers, graduate students, and students.
    Materialart: Online-Ressource
    Seiten: VIII, 146 p. 81 illus., 73 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031312489
    Serie: SpringerBriefs in Geography,
    URL: https://doi.org/10.1007/978-3-031-31248-9
    DOI: 10.1007/978-3-031-31248-9
    DDC: 910.285
    Sprache: Englisch
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  • 54
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    Online-Ressource
    Advanced Remote Sensing for Urban and Landscape Ecology (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Geographic information systems. ; Cartography. ; Urban ecology (Biology). ; Human geography. ; Geographical Information System. ; Cartography. ; Urban Ecology. ; Human Geography.
    Beschreibung / Inhaltsverzeichnis: Data And Urban Poverty: Detecting And Characterising Slums And Deprived Urban Areas In Low-And Middle-Income Countries -- Investigation Of Ecological Sustainability Through The Landscape Approach Of Geospatial Technology: Study From New Town Project In Eastern India -- Advanced Remote Sensing For Sustainable Decent Housing For The Economically Challenged Urban Households -- Impact Of Uncontrolled Tourism Development On Landscape Ecology Of Purba Medinipur Coastal Region, West Bengal: A 4-C Framework And Swoc Analysis -- Impact Of Urban Heat Island: A Local-Level Urban Climate Phenomenon On Urban Ecology And Human Health -- Identification Of Environmental Epidemiology Through Advanced Remote Sensing Based On Ndvi -- Assessment Of Land Utilization Pattern And Their Relationship With Surface Temperature And Vegetation In Sikkim, India -- Monitoring Land Use And Land Cover Change Over Bhiwani District Using Google Earth Engine -- Image And Perception Of Royal Heritage And Eco-Space Of The Medium Towns In India: Reflection From Burdwan Royal Heritage Site -- Governance And Floodplain Extent Changes Of Yamuna River Floodplain In Megacity Delhi -- Assessing Urban Compactness Using Machine Learning And Earth Observation Datasets: A Case Study Of Kolkata City -- Analysis Of Ecological Vulnerability Behind The Land Conversion From Agriculture To Aquaculture Of Purba Medinipur District In West Bengal, India -- Environmental Change Analysis Using Remote Sensing And Gis: A Study Of Upper Baitarani Basin, Odisha -- Mapping Urban Footprint Using Machine Learning And Public Domain Datasets.
    Kurzfassung: This book introduces the use of various remote sensing data such as microwave, hyperspectral and very high-resolution (VHR) satellite imagery; mapping techniques including pixel and object-based machine learning; and geostatistical modelling techniques including cellular automation, entropy and land fragmentation. Remote sensing plays a vital role in solving urban and environmental challenges at the landscape level. Globally, more than half of the urban population is facing severe environmental and social challenges, especially those relating to climate change, agricultural land encroachment, green infrastructure and environmental degradation, mobility due to rapid rural–urban transformation and anthropogenic interventions. Mapping and quantification of such threats at the landscape level are challenging for experts using traditional techniques; however, remote sensing technology provides diverse spatial data at a varying scale, volume and accessibility for mapping and modelling, and it also analyses challenges at urban and landscape levels. Together, they address challenges at urban and landscape levels to support the Sustainable Development Goals (SDGs).
    Materialart: Online-Ressource
    Seiten: XIII, 317 p. 153 illus., 129 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819930067
    Serie: Advances in Geographical and Environmental Sciences,
    URL: https://doi.org/10.1007/978-981-99-3006-7
    DOI: 10.1007/978-981-99-3006-7
    DDC: 910.285
    Sprache: Englisch
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  • 55
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    Online-Ressource
    Remote Sensing Big Data (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Big data. ; Database management. ; Algorithms. ; Data mining. ; Geographical Information System. ; Big Data. ; Database Management. ; Algorithms. ; Data Mining and Knowledge Discovery.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Introduction -- Chapter 2: Remote Sensing -- Chapter 3: Special Features of Remote Sensing Big Data -- Chapter 4: Remote Sensing Big Data Collection Challenges and Cyberinfrastructure and Sensor Web Solutions -- Chapter 5: Remote Sensing Big Data Computing -- Chapter 6: Remote Sensing Big Data Management -- Chapter 7: Standards for Big Data Management -- Chapter 8: Implementation Examples of Big Data Management Systems for Remote Sensing -- Chapter 9: Big Data Analytics for Remote Sensing-Concepts and standards -- Chapter 10: Big Data Analytic Platforms -- Chapter 11: Algorithmic Design Considerations of Big Data Analytics -- Chapter 12: Machine learning and data mining algorithms for geospatial big data -- Chapter 13: Modeling, prediction, and decision making based on remote sensing big data -- Chapter 14: Examples of remote sensing applications of big data analytics-fusion of diverse earth observation data -- Chapter 15: Examples of remote sensing applications of big data analytics-agricultural drought monitoring and forecasting -- Chapter 16: Examples of remote sensing applications of big data analytics-land cover time series creation -- Chapter 17: Geospatial big data initiatives in the world -- Chapter 18: Challenges and opportunities in remote sensing big data.
    Kurzfassung: This monograph provides comprehensive coverage of the collection, management, and use of big data obtained from remote sensing. The book begins with an introduction to the basics of big data and remote sensing, laying the groundwork for the more specialized information to follow. The volume then goes on to address a wide variety of topics related to the use and management of remote sensing big data, including hot topics such as analysis through machine learning, cyberinfrastructure, and modeling. Examples on how to use the results of big data analysis of remotely sensed data for concrete decision-making are offered as well. The closing chapters discuss geospatial big data initiatives throughout the world and future challenges and opportunities for remote sensing big data applications. The audience for this book includes researchers at the intersection of geoscience and data science, senior undergraduate and graduate students, and anyone else interested in how large datasets obtained through remote sensing can be best utilized. The book presents a culmination of 30 years of research from renowned spatial scientists Drs. Liping Di and Eugene Yu.
    Materialart: Online-Ressource
    Seiten: XI, 295 p. 104 illus., 95 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031339325
    Serie: Springer Remote Sensing/Photogrammetry,
    URL: https://doi.org/10.1007/978-3-031-33932-5
    DOI: 10.1007/978-3-031-33932-5
    DDC: 910.285
    Sprache: Englisch
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  • 56
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    Geoinformatics in Theory and Practice : An Integrated Approach to Geoinformation Systems, Remote Sensing and Digital Image Processing (2023)
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Details
    Schlagwort(e): Geographic information systems. ; Environmental monitoring. ; Dynamics. ; Nonlinear theories. ; Geography. ; Environmental sciences Mathematics. ; Geographical Information System. ; Environmental Monitoring. ; Applied Dynamical Systems. ; Geography. ; Mathematical Applications in Environmental Science.
    Beschreibung / Inhaltsverzeichnis: 1 Introduction -- 2 Basic terms and general principles of information processing -- 3 Basics from computer science -- 4 Spatial objects and reference systems -- 5 Digital spatial data: Data mining, geographic reference data and VGI -- 6 Standards and interoperability of spatial data -- 7 Visualization of spatial information -- 8 Data organization and database systems -- 9 Geographic information systems -- 10 Remote sensing and digital image processing.
    Kurzfassung: This textbook is intended to display a broad, methodological introduction to geoinformatics and geoinformation science. It deals with the recording, modeling, processing and analysis as well as presenting and distributing of geodata. As an integrated approach it is dedicated to the multidisciplinary application of methods and concepts of computer science to solve spatial tasks. First the reader receives an introduction to the approach and tasks of geoinformatics, basic concepts and general principles of information processing as well as essentials of computer science. Then this textbook focuses on the following topics: spatial reference systems, digital spatial data, interoperability of spatial data, visualization of spatial information, data organization and database systems, geoinformation systems, remote sensing and digital image processing. The result is a comprehensive manual for studies and practical applications in geoinformatics. It serves also as a basis to support and deepen methodological courses in geography, geology, geodesy and surveying as well as all environmental sciences. In this first English edition, the author has updated and significantly expanded the fourth German edition. New additions include the development of apps, graphical presentation on the web, geodata-bases and recent methods of classification. This book is based on the original German 4th edition Geoinformatik in Theorie und Praxis by Norbert de Lange, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2020 and still presents the only integrated perspective on geoinformatics and geoinformation science. This book was translated with the help of artificial intelligence (machine translation by the service DeepL.com) first and then significantly revised with regard to technical terms and special topics of geoinformatics. The author Norbert de Lange taught and conducted research at the Institutes of Geography at the Universities of Münster and Osnabrück, Germany. In 2005, he was involved in founding the Institute for Geoinformatics and Remote Sensing at the University of Osnabrück, which has merged with the Institute for Computer Science and where he has been a Professor of Environmental Informatics and Municipal Planning since 2016. His main research focuses on applications of geoinformatics in urban and regional planning. For more than 40 years he has been teaching courses on geoinformation systems, digital cartography and data analysis in earth sciences.
    Materialart: Online-Ressource
    Seiten: XVI, 519 p. 217 illus., 146 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783662657584
    Serie: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-662-65758-4
    DOI: 10.1007/978-3-662-65758-4
    DDC: 910.285
    Sprache: Englisch
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  • 57
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    ArcGIS Pro and ArcGIS Online : Applications in Water and Environmental Sciences (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Environment. ; Geography. ; Geographical Information System. ; Environmental Sciences. ; Geography.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Introduction to ArcGISPro -- Chapter 2: Data Classification and Layout in ArcGISPro -- Chapter 3: Data Acquisition -- Chapter 4: Coordinate Systems and Projections -- Chapter 5: Working with Geodatabase -- Chapter 6: Data Editing and Topology -- Chapter 7: Geoprocessing -- Chapter 8: Site Suitability and Data Modelling -- Chapter 9: Geocoding -- Chapter 10: Working with Raster -- Chapter 11: Spatial Interpolation -- Chapter 12: Watershed Delineation -- Chapter 13: Special Statistics -- Chapter 14: Network Analyst -- Chapter 15: 3-D Analyst -- Chapter 16: ArcGIS Online and Web Maps.
    Kurzfassung: This textbook serves as a practical guide for undergraduate and graduate students in geology, hydrology, ecology, and environmental sciences, teaching them applied GIS techniques. Presented as a step-by-step tutorial across seventeen chapters, the book starts with the fundamentals of GIS and progresses to real-life examples from geology and water resources. The focus is on ESRI's ArcGIS Pro, covering various tools for spatial, geostatistical, network, and 3-D analysis. Additionally, it explores ArcGIS Online and working with web apps like Web Map, StoryMaps, and GEO App. GIS applications, especially in water and environmental problem-solving, are rapidly growing worldwide. The demand for GIS experts utilizing spatial analysis in environmental science remains high. This textbook equips users with the necessary knowledge to become effective mappers and spatial analysts in the fields of environment, geosciences, and water resources, employing the latest state-of-the-art methodology. Each chapter provides exercises and supplementary materials available for download on SpringerLink, along with additional links for further learning opportunities.
    Materialart: Online-Ressource
    Seiten: XIX, 424 p. 669 illus., 653 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031422270
    Serie: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-031-42227-0
    DOI: 10.1007/978-3-031-42227-0
    DDC: 910.285
    Sprache: Englisch
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    Online-Ressource
    Physical Geodesy : A Theoretical Introduction (2023)
    Cham :Springer Nature Switzerland :
    Details
    Schlagwort(e): Geographic information systems. ; Physical geography. ; Geomorphology. ; Geographical Information System. ; Physical Geography. ; Geomorphology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Earth’s Gravity Field and Some of its Properties -- Chapter 2. Elementary Potential Theory -- Chapter 3. Spherical Harmonics -- Chapter 4. Normal Gravity Field and Reference Earth Ellipsoid -- Chapter 5. Stokes’ Theory and Beyond -- Chapter 6. Gravity Reduction -- Chapter 7. Molodensky’s Theory and Beyond -- Chapter 8. Fundamentals of Computation and Determination -- Chapter 9. Flattening and Gravity Inside the Earth.
    Kurzfassung: This textbook introduces physical geodesy. It treats the boundary-value theories of the discipline comprehensively, and provides insights to the theory of gravity reduction based on a spherical Earth model. This book is for students who wish to thoroughly understand the material and to expand their knowledge and skills in mathematics for more advanced study and research in this discipline. The details of mathematical derivations included are a useful asset for instructors and researchers.
    Materialart: Online-Ressource
    Seiten: XXI, 501 p. 96 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031233203
    Serie: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-031-23320-3
    DOI: 10.1007/978-3-031-23320-3
    DDC: 910.285
    Sprache: Englisch
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  • 59
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    LGBT Populations and Cancer in the Global Context (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical policy. ; Quality of life. ; Biomedical Research. ; Health Policy. ; Quality of Life Research.
    Beschreibung / Inhaltsverzeichnis: Foreword: Challenges & Opportunities for LGBT Populations and Cancer in Global Oncology -- Introduction -- Africa -- A Double Dose Of Stigma – Being Gay And Living With Cancer In Kenya -- Sexual Orientation, Gender Identity and Cancer in South Africa -- Americas -- Making the Situation of TLGBI People around Cancer visible: Observations from the Andean Region -- Cancer Care Challenges for the LGBT Population in Brazil -- Cancer and the SGM Population in Canada and the United States of America -- South-East Asia -- The South-East Asia Region: Societal Conditions for LGBT Health and Cancer Research -- Europe -- Foreword: The Eurocentralasian Lesbian* Community Perspective on Cancer and LBQ women: Advocating for more Research and Activism Collaboration -- LGBT+ and Cancer in the WHO European Region: Current Situation in 12 Eastern European and Central Asian Countries -- Sexual and Gender Minorities and Cancer in Germany: The Striking Absence of Understanding their Cancer-related Needs -- LGBT Populations and Cancer in the UK -- Eastern Mediterranean -- LGBT Populations and Cancer in the Eastern Mediterranean Region: Insights and Challenges with a Focus on Lebanon -- Western Pacific -- LGBT Populations and Cancer in Australia and New Zealand -- Challenges in Cancer Control Confronting the LGBT Population in China: Health Risks, Unique Barriers, and Unmet Needs -- What Have We Learned about Cancer and the Global LGBT Community? -- Index.
    Kurzfassung: Lesbian, Gay, Bisexual, and Transgender (LGBT) also known as sexual and gender minority (SGM) populations have been the focus of global attention. Most importantly, LGBT populations have been addressed in the context of human rights in multiple reports and other activities by the United Nations and other international organizations. There is great variation among countries in the recognition of LGBT individuals’ human rights. A global focus on LGBT populations’ health is still limited, with the notable exception of HIV research. This book on LGBT populations and cancer in the global context is, therefore, an important step in that it will broaden the focus on LGBT populations’ health. Globally, cancer is the second leading cause of death. Cancer morbidity and mortality are increasing disproportionately among populations in lower-income countries. A review conducted by the World Health Organization (WHO) found that of the 82% of member states (158) countries, only 35% of the national cancer control plans addresses vulnerable population, including LGBT populations. These findings reflect an increasing awareness about equity when addressing cancer prevention and control, including LGBT populations. This book addresses LGBT populations’ cancer burden across countries that range from high- to low-income countries to support efforts in diverse countries that are working towards reducing LGBT populations’ cancer burden. It documents place-specific challenges that impede progress towards reducing the LGBT cancer burden as well as critically assesses the variation in cancer control efforts that target LGBT populations and cancer to support progress at a global scale. This book includes six sections that cover the six WHO regions, with each chapter written by an author from the specific region s/he is covering. Each chapter makes use of a template that contextualizes the region, local data collection/availability, risk factors, cancer prevention, detection, diagnosis, treatment, and survivorship.
    Materialart: Online-Ressource
    Seiten: X, 335 p. 3 illus., 2 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031065859
    URL: https://doi.org/10.1007/978-3-031-06585-9
    DOI: 10.1007/978-3-031-06585-9
    DDC: 610.72
    Sprache: Englisch
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    Periodontitis : Advances in Experimental Research (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical microbiology. ; Parasitology. ; Biomedical Research. ; Medical Microbiology. ; Parasitology.
    Beschreibung / Inhaltsverzeichnis: Preface -- Chapter1. Advances in experimental research about periodontitis: lessons from the past, ideas for the future (Julien Santi-Rocca) -- Part I: Periodontal microbiota -- Chapter 2. Microbiota in Periodontitis: advances in the omic era (Shao Bing Fong, Emile Boyer, Martine Bonnaure-Mallet, Vincent Meuric) -- Chapter 3. Aggregatibacter actinomycetemcomitans: from basic to advanced research (Abdelhadi Hbibi, Amal Bouziane, Badiaa Lyoussi, Mimoun Zouhdi, Driss Benazza) -- Chapter 4. Meta-analyses on the Periodontal Archaeome (Jéssica Alves de Cena, Yuri Silvestre-Barbosa, Aline Belmok, Cristine Miron Stefani, Cynthia Maria Kyaw, Nailê Damé-Teixeira) -- Chapter 5. Parasites in periodontal health and disease: a systematic review and meta-analysis (David Felipe Martin-Garcia, Malik Sallam, Gabriela Garcia, Julien Santi-Rocca) -- Chapter 6. Fungi - a component of the oral microbiome involved in periodontal diseases (Justyna Karkowska-Kuleta, Dorota Satala, Magdalena Smolarz, Marcin Zawrotniak, Maria Rapala-Kozik) -- Chapter 7. Herpesviruses in periodontitis: An umbrella review (Aleksandar Jakovljevic, Miroslav Andric, Jelena Jacimovic, Jelena Milasin, Javier Enrique Botero) -- Part II: Periodontitis pathophysiology -- Chapter 8. Recent updates on microbial biofilms in periodontitis: an analysis of in vitro biofilm models (Maick Meneguzzo Prado, Nathalia Figueiredo, Andréa Pimenta, Tamires Szeremeske Miranda, Magda Feres, Luciene Cristina Figueiredo, Josiane de Almeida, Bruno Bueno-Silva) -- Chapter 9. Update on B cell response in periodontitis (Julien Demoersman, Jacques Olivier Pers) -- Chapter 10. Polarization profiles of T lymphocytes and macrophages responses in periodontitis (Franco Cavalla, Marcela Hernández) -- Chapter 11. Complementary experimental methods in genetics open up new avenues of research to elucidate the pathogenesis of periodontitis (Arne S. Schaefer) -- Part III: Periodontitis-associated conditions -- Chapter 12. Update on the bidirectional link between diabetes and periodontitis (Leila Salhi, Michèle Reners) -- Chapter 13. Periodontitis as a risk factor for Alzheimer’s disease: the experimental journey so far, with hope of therapy (Alice Harding, Shalini Kanagasingam, Richard Welbury, Sim K. Singhrao) -- Chapter 14. Cardiovascular diseases and periodontitis (Peter Riis Hansen, Palle Holmstrup) -- Part IV: Therapeutic management of periodontitis -- Chapter 15. Update on the role of cytokines as oral biomarkers in the diagnosis of periodontitis (Triana Blanco-Pintos, Alba Regueira-Iglesias, Carlos Balsa-Castro, Inmaculada Tomás) -- Chapter 16. Non-surgical periodontal treatment: SRP and innovative therapeutic approaches (Alexia Vinel, Antoine Al Halabi, Sébastien Roumi, Hélène Le Neindre, Pierre Millavet, Marion Simon, Constance Cuny, Jean-Sébastien Barthet, Pierre Barthet, Sara Laurencin-Dalicieux) -- Chapter 17. Update on the roles of oral hygiene and plaque control on periodontal disease (Leila Salhi, Bruno De Carvalho, Michèle Reners) -- Chapter 18. Multi-photonic adjunctive therapy for the management of periodontitis: recent advances and new treatment approach (Marco Giannelli, Daniele Bani) -- Chapter 19. Probiotics during the therapeutic management of periodontitis (Flavia Furlaneto, Karin Hitomi Ishikawa, Michel Reis Messora, Marcia P A Mayer) -- Chapter 20. Periodontal cell therapy: a systematic review and meta-analysis (Antoine Dubuc, Valérie Planat-Bénard, Mathieu Marty, Paul Monsarrat, Philippe Kémoun) -- Index.
    Kurzfassung: Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendations for health professionals. A better information of the empowered patients, leading them to consider prevention and to take part in their therapeutic course. The book “Periodontitis: Advances in Experimental Research” includes a timely collection of chapters covering all the fields of research about periodontitis, consisting in concise reviews by the best specialists themselves and with clinical perspectives for periodontitis. Recent technological advances have allowed to explore shadowed areas of periodontology. The book “Periodontitis: Advances in Experimental Research” is a unique occasion to set a milestone for a more integrated field of periodontitis, with a broad scientific, medical, and public audience thanks to dedicated sections in each chapter: Abstract and main body (scientific audience and expert clinicians) Highlights (scientific audience and clinicians) Impact for Practice (clinicians and economical/political decision makers) Summary for Patients (patients and economical/political decision makers).
    Materialart: Online-Ressource
    Seiten: XIII, 402 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030968816
    Serie: Advances in Experimental Medicine and Biology, 1373
    URL: https://doi.org/10.1007/978-3-030-96881-6
    DOI: 10.1007/978-3-030-96881-6
    DDC: 610.72
    Sprache: Englisch
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    Biomedical Translational Research : Technologies for Improving Healthcare (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Cancer. ; Technology Sociological aspects. ; Genomics. ; Biomedical Research. ; Cancer Biology. ; Emerging Technologies. ; Genomics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to emerging technologies in biomedical sciences -- Chapter 2. Bioprospecting : boon or curse -- Chapter 3. Growing need for interdisciplinary biomedical research -- Chapter 4. Interplay between theory and experiment : a future approach for biomedical research -- Chapter 5.past, present and future perspectives of biomedical innovation in india -- Chapter 6. Systems biology approaches to study disease comorbidities -- Chapter 7. Bioinformatics the interactome of multidisciplinary approaches -- Chapter 8. Role of artificial intelligence in diagnosis of infectious diseases -- Chapter 9. Dna digital data storage breakthroughs in biomedical research. Chapter 10. Biomedical applications cloud-based iot -- Chapter 11. Next generation sequencing in cancer research -- Chapter 12. Crispr: genome editing and beyond -- Chapter 13. Omics in tuberculosis diagnosis : today and tomorrow -- Chapter 14. Advances in proteomic approaches for chronic kidney disease -- Chapter 15. 3 d bioprinting of tissues and organs : a new paradigm in regenerative medicine and biomedical engineering -- Chapter 16. Virtual planning, rapid prototyping and 3-d printing in orthopedic surgery -- Chapter 17. Tissue chips: contemporary applications and advancementstissue chips: contemporary applications and advancements -- Chapter 18. Flow cytometry for measuring neutrophil function -- Chapter 19. Flow cytometer for understanding genome size variation among medicinal herbs and non-edible oil trees of northeast india -- Chapter 20. Raman spectroscopy applications for bacterial detection -- Chapter 21. Microfluidic point-of-care diagnostic devices: a contemporary relevance. Chapter 22. Fluorescent dots for breast cancer management -- Chapter 23. Molecular mimicry : unravelling the role of autoantibodies in autoimmune diseases and infertility -- Chapter 24. Strategies of vaccine development -- Chapter 25. Preclinical models of intimal hyperplasia and restenosis to predict clinical events and develop novel therapies -- Chapter 26. Sphingolipids : a roadmap from biomarker identification to clinical application -- Chapter 27. Future of gastrointestinal endoscopy -- Chapter 28. Beating heart in a box : the future of cardiac transplant -- Chapter 29. The journey of coronary stent technology -- Chapter 30. Materiovigilance in clinical surgery.
    Kurzfassung: This book, which is the first volume of Biomedical Translational Research, summarizes emerging technologies in healthcare. The book reviews the advancements in biomedical sciences in genomics, immunology, stem cell, tissue engineering, nanotechnology, computational and structural biology, biomedical engineering, and telemedicine biology. The book highlights the applications of artificial intelligence in the diagnosis of infectious diseases and examines the role of system biology approaches for understanding human complexity, variability, and its influence on health and diseases. It presents the applications of flow cytometry in monitoring the progression and treatment of disease. It covers emerging technologies in cancer research, including CRISPR-Cas9, NGS, and nanotechnology. This book is a useful source of information for clinical researchers, basic scientists, biomedical engineers, and computational biologists.
    Materialart: Online-Ressource
    Seiten: XIII, 505 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811643453
    URL: https://doi.org/10.1007/978-981-16-4345-3
    DOI: 10.1007/978-981-16-4345-3
    DDC: 610.72
    Sprache: Englisch
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    Microbes and Oral Squamous Cell Carcinoma : A Network Spanning Infection and Inflammation (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical microbiology. ; Microbial genetics. ; Industrial microbiology. ; Microbiology. ; Biomedical Research. ; Medical Microbiology. ; Microbial Genetics. ; Industrial Microbiology. ; Microbiology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Epidemiology of Oral Squamous Cell Carcinoma in Indian Scenario -- Chapter 2. Risk factors for Oral Squamous Cell Carcinoma in the Indian population -- Chapter 3. Molecular Carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 4. Inflammation and Infection in Cancer -- Chapter 5. Role of Inflammation and Infection in Oral Squamous Cell Carcinoma -- Chapter 6. Normal Microbiome of Oral cavity -- Chapter 7. Oral Microbiome in Oral Squamous Cell Carcinoma -- Chapter 8. Microbial Dysbiosis in Oral Squamous Cell Carcinoma -- Chapter 9. Bacteria induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 10. Virus induced carcinopathogenesis in Oral Squamous Cell Carcinoma -- Chapter 11. Fungi: Culprits or Bystanders in Oral Squamous Cell Carcinoma -- Chapter 12. Microbial ‘omics’ in Oral Squamous Cell Carcinoma -- Chapter 13. Implications and Future perspectives.
    Kurzfassung: This book helps in understanding the relationship between microorganisms and oral carcinogenesis, and the possible oncogenic mechanisms enhancing the association. The book highlights the association between oral cancer, primarily oral squamous cell carcinoma (OSCC), a major global health problem with high incidence and low survival rates with infection and inflammation. Establishing the association of the oral microbiome with cancer risk may lead to significant advances in the understanding cancer etiology, potentially opening a new research paradigm for cancer prevention. The book takes the readers through interesting topics such as the epidemiology and etiology of OSCC, the hallmarks of cancer, and the role of inflammation in OCSS. It presents the difference between the normal and diseased oral microbiome. It further describes the carcino-pathogenesis of various groups. Finally, it discusses the clinical correlation of the observations and what the future looks like for this area of research. The book is interesting for medical students, researchers and clinicians, alike. The knowledge from the book can be exploited practically and used for designing further experiments.
    Materialart: Online-Ressource
    Seiten: XIII, 172 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811905926
    URL: https://doi.org/10.1007/978-981-19-0592-6
    DOI: 10.1007/978-981-19-0592-6
    DDC: 610.72
    Sprache: Englisch
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    Regionalized Management of Medicine (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Therapeutics. ; Medical informatics. ; Translational Research. ; Therapeutics. ; Health Informatics.
    Beschreibung / Inhaltsverzeichnis: Introduction: The importance of regionalized management of medicine -- Alcohol use disorders -- Public-private partnerships management in health care: The Portuguese experience -- Management of Clinical Precision Medicine -- Artificial Intelligence in medical management -- Advanced Demand Forecasting and Inventory Management Methods in Hospital Pharmacy -- Clinical Application of Cell-Based Therapies Opportunities and Challenges -- Management of Next-Generation Sequencing (NGS) in Precision Medicine -- Exploration on the Reform of County Medical Integration -- The Regionalization of Medical Management: The Practice and Exploration of Established Fudan-Minhang Medical Alliance -- Bed-occupancy management and hospital planning: a handbook -- Management of severe childhood pneumonia in low resource setting -- The role of mitochondrial-targeted antioxidant, MitoQ, in neurodegenerative disease -- Progression of mitochondria research for clinical potentials -- DNA methylation in pulmonary inflammatory diseases -- Synthetic lethality and lung cancer.
    Kurzfassung: The Book mainly focuses on various aspects of regionalized management of medicine, related with updates of new biotechnology, application of therapeutic strategy, and understanding of disease-associated molecular mechanisms. The book also discusses how medical informatics, systems analysis, database sharing, and artificial intelligent can be applied for improving the quality of hospital managements, disease therapies, regional collaborations, and medical services. This book serves as a professional reference book to clinicians and experts who are interested in medical informatics and artificial intelligence for diseases therapies and therapeutic strategy, better systems analysis and database sharing, and more efficient regional collaborations and medical services.
    Materialart: Online-Ressource
    Seiten: X, 226 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811678936
    Serie: Translational Bioinformatics, 17
    URL: https://doi.org/10.1007/978-981-16-7893-6
    DOI: 10.1007/978-981-16-7893-6
    DDC: 610.72
    Sprache: Englisch
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  • 64
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    Microfluidics and Multi Organs on Chip (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biomedical engineering. ; Toxicology. ; Cytology. ; Biomedical Research. ; Biomedical Devices and Instrumentation. ; Toxicology. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. A Historical and Technological Background to Organs-on-a-Chip -- Chapter 2. Applications of microfluidics -- Chapter 3. Microfluidics based Organ-on-a-chip for cell biology studies -- Chapter 4. Microfluidics in Chemical biology -- Chapter 5. Role of microfluidics in drug delivery -- Chapter 6. Microfluidics in drug discovery -- Chapter 7. Microfludic based sensors -- Chapter 8. Background and Organs-on-a-Chip -- Chapter 9. Culture and co-culture of cells for multi organ on chip -- Chapter 10.Cells and organs on a chip in biomedical sciences -- Chapter 11. Futuristic aspects of organ on a chip -- Chapter 12. Development of Human on a chip -- Chapter 13. Multi-organ on a chip for personalized medicine -- Chapter 14. Development and application of Microfluids in organoid formation -- Chapter 15. Liver on a chip -- Chapter 16. Placenta on Chip: A Modern approach to probe feto-maternal interface -- Chapter 17. Microfluidic retina-on-chip -- Chapter 18. Heart on a chip -- Chapter 19. Kidney on a chip -- Chapter 20. Lungs on a chip -- Chapter 21. Brain on a chip -- Chapter 22. Skin on a chip -- Chapter 23. Organs-on-a-chip in preclinical studies -- Chapter 24. Application of organ on chip in blood brain barrier model -- Chapter 25. Multi organs on a chip in disease modeling -- Chapter 26. Prospects of Medical device on a chip -- Chapter 27. Lab on a chip for precision Medicine -- Chapter 28. Tumour-on-a-chip : Perfusion systems to model the extracellular breast tumour microenvironment:from tumour progression to metastasis formation -- Chapter 29. Building Human In Vitro 3D Models to Replace Animal Studies: During Drug Discovery Reearch: Scientific, Ethical and Regulatory Considerations.
    Kurzfassung: This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
    Materialart: Online-Ressource
    Seiten: IX, 717 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811913792
    URL: https://doi.org/10.1007/978-981-19-1379-2
    DOI: 10.1007/978-981-19-1379-2
    DDC: 610.72
    Sprache: Englisch
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    Biomedical Translational Research : Drug Design and Discovery (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Drugs Design. ; Pharmaceutical chemistry. ; Genomics. ; Bioinformatics. ; Biomedical Research. ; Structure-Based Drug Design. ; Pharmaceutics. ; Genomics. ; Bioinformatics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management.
    Kurzfassung: This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.
    Materialart: Online-Ressource
    Seiten: XII, 599 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811692321
    URL: https://doi.org/10.1007/978-981-16-9232-1
    DOI: 10.1007/978-981-16-9232-1
    DDC: 610.72
    Sprache: Englisch
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    Basic Organic Chemistry for the Life Sciences (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Life sciences. ; Chemistry, Organic. ; Enzymology. ; Biochemistry. ; Biomedical Research. ; Life Sciences. ; Organic Chemistry. ; Enzymology. ; Biochemistry.
    Beschreibung / Inhaltsverzeichnis: 1. Alkanes, composition, constitution, and configuration -- 2. Functional groups -- 3. Electronic structure of organic molecules -- 4. Alkenes and alkynes -- 5. Substitutions on saturated carbon atom -- 6. Nucleophilic additions -- 7. Stereochemistry, symmetry, and molecular chirality -- 8. Derivatives of carboxylic acids -- 9. Electrophilic substitutions -- 10. Pericyclic reactions -- 11. Organic natural products -- 12. Organic supramolecular and supermolecular structures.
    Kurzfassung: This textbook is designed for students of biology, molecular biology, ecology,medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions.
    Materialart: Online-Ressource
    Seiten: XV, 205 p. 339 illus., 114 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2022.
    ISBN: 9783030924386
    URL: https://doi.org/10.1007/978-3-030-92438-6
    DOI: 10.1007/978-3-030-92438-6
    DDC: 610.72
    Sprache: Englisch
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    Food Packaging: The Smarter Way (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Food science. ; Nanotechnology. ; Biomedical Research. ; Food Science. ; Food Engineering. ; Food Nanotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Chapter 1. Food packaging industry - An introduction -- Chapter 2. Toward Smarter Food Packaging -- Chapter 3. Novel packaging development, assessment and authentication using smart technologies, non-invasive biometric sensory tools, and artificial intelligence -- Chapter 4. Biodegradable packaging materials and techniques to improve their performance -- Chapter 5. Smart Freshness Indicator for Animal Based Products Packaging - Current Status.-Chapter 6. Packaging of dairy products-Emerging strategies -- Chapter 7. Functional packaging materials for fishery products applications -- Chapter 8. Edible films and coatings: Major challenges and potential applications in food Packaging: A Review.-Chapter 9. Role of sensors to improve food/beverage packaging -- Chapter 10. Functional nanomaterials for food packaging applications -- Chapter 11. Rules and regulations related with packaging.
    Kurzfassung: This book reviews the science and technology of food packaging and covers the potential innovations in the food packaging sector. At the same time, it highlights the issues and prospects for linking the laboratory research to the market. In addition to typical packaging requirements such as food quality, shelf life, protection, communication, and marketing, the book emphasizes the need for novel packaging materials, including biodegradable packaging for a variety of food products. A wide range of food products has been kept in focus and includes animal-based food products such as dairy products and sea foods. The book presents the next level of packaging solutions i.e., smart packaging with the applications of potential tools such as intelligent and active packaging, and includes the latest research on emerging digital technologies for packaging development, assessment, and acceptability. It further highlights the strategies including blends, reinforcing agents, cold plasma, UV light applications, chemical, and enzymatic methods and explores the new opportunities leading to improvement in the packaging performance. Smart freshness indicator applications, including gas and time-temperature indicators for quality and safety of packaged products, have been covered in detail. The book also includes the functional characteristics of edible films and coatings, including their bioactive characteristics. Finally the book presents the rules and regulation related to packaging.
    Materialart: Online-Ressource
    Seiten: XI, 286 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811671968
    URL: https://doi.org/10.1007/978-981-16-7196-8
    DOI: 10.1007/978-981-16-7196-8
    DDC: 610.72
    Sprache: Englisch
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    Targets of Cancer Diagnosis and Treatment : Ion Transport in Tumor Biology (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Internal medicine. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Internal Medicine. ; Physiology.
    Beschreibung / Inhaltsverzeichnis: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges -- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer -- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk -- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics -- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research -- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions -- Ion Transport and Radioresistance -- Ion Transporting Proteins and Cancer: Progress and Perspectives.
    Kurzfassung: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges Alina L. Capatina, Dimitris Lagos, and William J. Brackenbury Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk Jerry J. Fan and Xi Huang Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu Ion Transport and Radioresistance Bastian Roth and Stephan M. Huber Ion Transporting Proteins and Cancer: Progress and Perspectives Mustafa B. A. Djamgoz.
    Materialart: Online-Ressource
    Seiten: X, 277 p. 30 illus., 20 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031039942
    Serie: Reviews of Physiology, Biochemistry and Pharmacology, 183
    URL: https://doi.org/10.1007/978-3-031-03994-2
    DOI: 10.1007/978-3-031-03994-2
    DDC: 610.72
    Sprache: Englisch
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    Crime Scene Management within Forensic Science : Forensic Techniques for Criminal Investigations (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Forensic sciences. ; Toxicology. ; Biomedical Research. ; Forensic Science. ; Toxicology.
    Beschreibung / Inhaltsverzeichnis: 1 Forensic Dna Analysis: A Powerful Investigative Tool -- 2 “Crime Scene Management Within Forensic Science-Forensic Techniques For Criminal Investigations -- 3 Small Size, Big Impact: Insects For Cadaver Examination -- 4 Dermatoglyphics & Other Impressions: Deciphering The Potential Of A Unique Hominid Niche -- 5 Postmortem Toxicology: A facet of drugs of expedites crimes -- 6 Forensic Biology: A Passport For Biological Evidence -- 7 Sexual offences: Recent methods of Investigation -- 8 Investigation Of Disaster Victim Identification -- 9 Review On Clinical Forensic Medicine -- 10 Firearms and Ammunitions: A sentient approach in criminal investigation -- 11 Digital and Cyber Forensics: A Contemporary evolution in Forensic Sciences -- 12 Fire Investigation: Arson Or Accidental -- 13 Psychological Evaluations: An Indoor game of Criminal Minds -- 14 Competence of Evidences: A Pragmatic Approach in Court of Law -- 15 Penology: A friend or foe for criminal justice system -- 16 Chain Of Custody: Scaling The Investigation To The Event. .
    Kurzfassung: This book, the second volume of Crime Scene Management in Forensic Sciences, reviews the role and impact of forensic evidence in criminal investigations. It also addresses the importance of post mortem examination in criminal cases. The book investigates the use of insects and arthropods to estimate post mortem intervals during forensic investigations. Further, it discusses the physiological effects of xenobiotics at the time of death, based on their concentration and distribution in the body at autopsy. Importantly, it also discusses digital forensic investigation, which can be used for the analysis of digital evidence produced at a court of law. Lastly, it defines the structure and legal framework of these forensic evidences for the effective administration of the criminal justice system. It is an excellent source of information for forensics scientists and legal professionals.
    Materialart: Online-Ressource
    Seiten: VIII, 418 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811666834
    URL: https://doi.org/10.1007/978-981-16-6683-4
    DOI: 10.1007/978-981-16-6683-4
    DDC: 610.72
    Sprache: Englisch
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    Nuclear Receptors in Human Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Molecular biology. ; Metabolism. ; Genetics. ; Cytology. ; Biomedical Research. ; Molecular Biology. ; Metabolism. ; Genetics and Genomics. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Introduction (Moray J Campbell & Charlotte L Bevan) -- Overview (Jason Carroll) -- Part I: Reproduction and Development -- Chapter 1. Nuclear receptors in pregnancy and outcomes: clinical perspective (Luiza Borges Manna & Catherine Williamson) -- Chapter 2. Female Reproductive Systems: hormone dependence and receptor expression (Philippa TK Saunders) -- Chapter 3. Nuclear receptors in ovarian function (Darryl Russell & Doan Thao Dinh) -- Part II: Metabolism -- Chapter 4. Nuclear receptors in energy metabolism (Alina Walth, Stephan Herzig & Maria Rohm) -- Chapter 5. Nuclear Receptors and lipid sensing (James L Thorne and Giorgia Cioccoloni) -- Part III: Central Systems -- Chapter 6. Corticosteroid receptors in Cardiac health and disease (Jessica Ivy, Gillian Gray, Megan Holmes, Martin Denvir, Karen Chapman) -- Chapter 7. Physiological convergence and antagonism between GR and PPARγ in inflammation and metabolism (Marija Dacic, Gayathri Shibu and Inez Rogatsky) -- Chapter 8. Circadian Rhythm and Nuclear Receptors (David W Ray) -- Chapter 9. Vitamin D and gut health (James C Fleet) -- Part IV: Cancer -- Chapter 10. Estrogen Receptor alpha and ESR1 Mutations in Breast Cancer (Jaymin Patel & Rinath Jeselsohn) -- Chapter 11. AR structural variants and prostate cancer (Laura Cato) -- Chapter 12. ERβ and inflammation (Linnea Hases, Amena Archer & Cecilia Williams) -- Chapter 13. Genomic insights into non-steroidal nuclear receptors in prostate and breast cancer (Sajad A Wani & Moray Campbell) -- Part V: New developments in transcriptional control by nuclear receptors -- Chapter 14. Protein condensation in the nuclear receptor family; implications for transcriptional output (Monique Appelman, Elle Hollaar, Jurian Schuijers & Saskia WC van Mil) -- Chapter 15. Prostate cancer epigenetic plasticity and enhancer heterogeneity: molecular causes, consequences and clinical implications (Jeroen Kneppers, Andries M Bergman & Wilbert Zwart) -- Chapter 16. Epigenetic coregulation of androgen receptor signaling (Rayzel Fernandes, Damien A. Leach & Charlotte Bevan) -- Part VI: Clinical Translation -- Chapter 17. Cllnical Translation: Targeting the Estrogen Receptor (Jennifer O. Lauchle & Ciara Metcalfe) -- Chapter 18. Drugging the undruggable: targeting the N-terminal domain of nuclear hormone receptors (Marianne Sadar) -- Chapter 19. Genetic Variation and Mendelian Randomization approaches (Mojgan Yazdanpanah, Nahid Yazdanpanah & Despoina Manousaki) -- Index.
    Kurzfassung: This book addresses and dissects the roles and crosstalk mechanisms for the 48 human nuclear receptors (NR) in human health and disease. After a State-of-the-Art introduction by an undisputed and celebrated field leader to provide an overview of the field and its significance, chapters are organized into six sections. The first three sections discuss NR roles in Reproduction & Development, Metabolism and Central Systems. These present to the reader our current understanding of NR signaling in the development and functioning of the reproductive system; the roles in the regulation of energy metabolism; and how NR signaling is more widely integrated into systemic functions from calcium flux to circadian rhythm. The subsequent three sections dissect how aberrant NR functions drive Cancer; how new insights into Genomic Interaction are helping to reveal how NR disruption drives disease; and finally, how Translational Efforts are exploiting this understanding from developing novel NR ligands to establishing how underlying genetic variation impacts NR function. Within these sections the chapters also illustrate emerging understanding of how the epigenome and non-coding genome combine to regulate NR function and impact dysfunction. Increasingly these insights cross-fertilize over cell and disease boundaries and it is unsurprising that NR are being explored in novel and new arenas such as the context of neurological disorders and depression. Thus, there is wide scope for re-purposing of licensed drugs and development of new NR-targeting therapies for a host of conditions and diseases. This unique book brings together many of the leading figures in NR research from across the globe, to discuss emerging roles and their implications for human health and disease. It summarizes the state of the art and shows signposts for future research to further shape this influential field.
    Materialart: Online-Ressource
    Seiten: XII, 346 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031118364
    Serie: Advances in Experimental Medicine and Biology, 1390
    URL: https://doi.org/10.1007/978-3-031-11836-4
    DOI: 10.1007/978-3-031-11836-4
    DDC: 610.72
    Sprache: Englisch
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  • 71
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    Online-Ressource
    Medical Visualization and Applications of Technology (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Anatomy. ; Medical education. ; Virtual reality. ; Augmented reality. ; Biomedical Research. ; Anatomy. ; Medical Education. ; Virtual and Augmented Reality.
    Beschreibung / Inhaltsverzeichnis: Part I. Healthcare -- Chapter 1. Is It Time to FONA Friend? A Novel Mixed Reality Front of Neck Access Simulator -- Chapter 2. “Learning About Skin Breakdown” – Design, Development and Evaluation of an Augmented Reality Application to Inform about Pressure Ulcers (sores) and Moisture Lesions -- Chapter 3. The Use of 3D-Printing and Injection Moulding in the Development of a Low-Cost, Perfused Renal Malignancy Model for Training of Robot-Assisted Laparoscopic Partial Nephrectomy -- Chapter 4. The Co-IMMUNicate App: An Engaging and Entertaining Education Resource on Immunity to Respiratory Viruses -- Part II. Education -- Chapter 5. Application of AR and 3D Technology for Learning Neuroanatomy -- Chapter 6. Communicative Powers of Interactive Digital Mediums in the Field of Polyomics -- Chapter 7. SkilletonVR: Canine Skeleton VR -- Chapter 8. Using Holograms to Engage Young People with Anatomy -- Chapter 9. The Digital Dolphin: Are 3D Mobile Based and Interactive Models a Useful Aid to Volunteers on Stranding Schemes Learning the Basic Anatomy and Pathology of Cetaceans? -- Chapter 10. The Impact of the COVID Crisis on Anatomical Education: A Systematic Review.
    Kurzfassung: This edited book explores the use of technology to enable us to visualize the life sciences in a more meaningful and engaging way. It will enable those interested in visualization techniques to gain a better understanding of the applications that can be used in visualization, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualization techniques and technologies for the historical and forensic settings. The reader will be able to explore the utilization of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences. We have something for a diverse and inclusive audience ranging from healthcare, patient education, animal health and disease and pedagogies around the use of technologies in these related fields. The first four chapters cover healthcare and detail how technology can be used to illustrate emergency surgical access to the airway, pressure sores, robotic surgery in partial nephrectomy, and respiratory viruses. The last six chapters in the education section cover augmented reality and learning neuroanatomy, historical artefacts, virtual reality in canine anatomy, holograms to educate children in cardiothoracic anatomy, 3D models of cetaceans, and the impact of the pandemic on digital anatomical educational resources.
    Materialart: Online-Ressource
    Seiten: IX, 323 p. 270 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031067358
    Serie: Biomedical Visualization, 1
    URL: https://doi.org/10.1007/978-3-031-06735-8
    DOI: 10.1007/978-3-031-06735-8
    DDC: 610.72
    Sprache: Englisch
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  • 72
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    Online-Ressource
    Microbial Engineering for Therapeutics (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biomedical engineering. ; Industrial microbiology. ; Bioinformatics. ; Synthetic Biology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Industrial Microbiology. ; Computational and Systems Biology. ; Synthetic Biology.
    Beschreibung / Inhaltsverzeichnis: Part 1 Introduction to Microbial Engineering -- 1 Exploring the Potential of Microbial Engineering: The Prospect, Promise and Essence -- Part 2 Microbial Engineering Approaches -- 2 Role of System Biology in Microbial System -- 3 Synthetic Biology: Refining Human Health -- 4 Probiotic Engineering: A focus on Inflammatory Bowel Disease -- 5 Engineering microbes for smart diagnostics & Lab on Chip -- 6 Bacteriophage and Virus Engineering -- 7 CRISPR Technologies: A tool for Engineering Microbes -- Part 3 Health Benefits -- 8 Recombinant Vaccines: The Revolution Ahead -- 9 Microbe-Host Metabolic Interaction- Probiotic Approach -- 10 Designer Microbes: Oncotherapy approach -- 11 The human gut microbiome in health, disease and therapeutics -- 12 Use of Engineered Bacteria for Production of Green Chemicals & Pharmaceuticals -- 13 Fat Fighting Microbes. Part 4 Innovation & Translation -- 14 Scale-up of engineering strain for industrial applications -- 15 Affordable therapeutics through Engineered Microbes -- 16 COVID-19: Lesson Learnt from Diagnostics to therapeutics. .
    Kurzfassung: This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.
    Materialart: Online-Ressource
    Seiten: XI, 374 p. 45 illus., 44 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811939792
    URL: https://doi.org/10.1007/978-981-19-3979-2
    DOI: 10.1007/978-981-19-3979-2
    DDC: 610.72
    Sprache: Englisch
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  • 73
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    Online-Ressource
    Handbook of Millets - Processing, Quality, and Nutrition Status (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Food science. ; Agriculture. ; Biomedical Research. ; Food Science. ; Agriculture.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Millets-an Overview -- Chapter 2. Millet Cultivation an Overview -- Chapter 3. Millet Storage and Pest Management -- Chapter 4. Major Millets Processing -- Chapter 5. Minor millet processing and its impacts on composition -- Chapter 6. Chemistry of Millets: Major and Minor Constituents -- Chapter 7. Nutritional properties of millets: neglected cereals with potentials to combat malnutrition -- Chapter 8. Post-harvest Treatments and Storage of millets -- Chapter 9. Millet Milling Technologies -- Chapter 10. Effect of Processing on Functional Characteristics, Physiochemical Properties, and Nutritional Accessibility of Millets -- Chapter 11. Emerging Technologies in Millet Processing -- Chapter 12. Millet Food Products -- Chapter 13. Byproducts from Millet Processing Industry -- Chapter 14. Quality Standards for Millets -- Chapter 15. Millet Industry Scenario -- Chapter 16. Toxins in Millets.-.
    Kurzfassung: The book offers an updated perspective on the unique characteristics of millets. Millets are consumed for their health/nutritional benefits, and in the preparation of specialty foods for target groups – from pediatrics to geriatrics. Recent trends suggest the importance of millet in the human diet due to their nutritional importance, ability to grow in high temperatures and drought conditions, and their resistance to pests and diseases. This book highlights different types of millet and discusses their properties as well as nutritional and anti-nutritional values. In addition, the book also provides information on the physiochemical properties, future prospects, current methodologies, and agricultural practices. The last few parts cover the emerging technologies in millet processing, by-products utilization, quality standards, and the current millet industry scenario. The book provides a comprehensive overview of the status of millet processing, quality, and nutraceutical product manufacture. The book is a resourceful read for students and researchers in food sciences, as well as industry experts.
    Materialart: Online-Ressource
    Seiten: VII, 386 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811672248
    URL: https://doi.org/10.1007/978-981-16-7224-8
    DOI: 10.1007/978-981-16-7224-8
    DDC: 610.72
    Sprache: Englisch
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  • 74
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    Online-Ressource
    Polymeric nanoparticles for the treatment of solid tumors (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Nanotechnology. ; Cancer Treatment. ; Biomedical Research. ; Nanotechnology. ; Cancer Therapy.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. The tumor microenvironment -- Chapter 2. Methods of formulation of polymeric nanoparticles -- Chapter 3. Natural polymers based nanoparticles targeted to solid tumors -- Chapter 4. Optimization of physicochemical properties of polymeric nanoparticles for targeting solid tumors -- Chapter 5. Passive and active targeting approaches for solid tumors -- Chapter 6. Polymeric nanoparticles entrapping natural drugs for cancer therapy -- Chapter 7. Polymeric nanoparticles entrapping drug combinations targeted to solid tumors -- Chapter 8. Ligands specific to over-expressed receptors in solid tumors -- Chapter 9. Ligand targeted polymeric nanoparticles for cancer chemotherapy -- Chapter 10. Polymeric nanoparticles as theranostics for targeting solid tumors -- Chapter 11. Oral delivery of polymeric nanoparticles for solid tumors -- Chapter 12. Polymeric nanoparticles to target glioblastoma tumors -- Chapter 13. Polymeric nanoparticles to target lung cancer -- Chapter 14. Polymer based nanoplatforms for targeting breast cancer -- Chapter 15. PH-Sensitive polymeric nanoparticles for cancer treatment -- Chapter 16. Polymeric nanoplatforms for targeted treatment of prostate cancer -- Chapter 17. Cellular internalization and toxicity of polymeric nanoparticles -- Chapter 18. Prospects and challenges in the treatment of solid tumors.
    Kurzfassung: This book focuses on the emerging research in the field of treatment of solid tumors or cancer with new drug delivery systems using nanotechnology. Nanotechnology has given us a good scope for development of new innovative drug delivery strategies to increase the therapeutic efficacy of anticancer drugs with reduced off-target side effects. Cancer is one of the main causes of death worldwide due to the limitations of classical therapies such as low solubility of active drugs, toxic side effects on healthy cells and resistance of tumor cells. These issues are partly solved by the recent development of polymeric nanoparticles, which improve drug absorption and the therapeutic index, while reducing side effects. Drug carriers must be biocompatible, biodegradable and non-immunogenic. Coupled to a ligand that has affinity for that particular cell, polymeric nanoparticles are used to target specifically malignant cells or tissues and, in turn, improve drug stability. This book presents the latest advances in the application of polymeric particles for cancer treatment, with focus on the tumor microenvironment, synthesis, active and passive targeting, patents, targeting over-expressed receptors, tumor-targeting ligands, theranostics, glioblastoma tumors, lung cancer, breast cancer, prostate cancer and pH-responsive nanoparticles.
    Materialart: Online-Ressource
    Seiten: X, 512 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031148484
    Serie: Environmental Chemistry for a Sustainable World, 71
    URL: https://doi.org/10.1007/978-3-031-14848-4
    DOI: 10.1007/978-3-031-14848-4
    DDC: 610.72
    Sprache: Englisch
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  • 75
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    Online-Ressource
    Hair Follicle Regeneration (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Stem cells. ; Biotechnology. ; Biomedical Research. ; Stem Cell Biology. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. The historical studies underpinning the concept of hair follicle neogenesis (Higgins C, Jahoda C) -- Chapter 2. Hair regeneration and rejuvenation: pipeline of medical and technical strategies (Limbu S, Kemp P) -- Chapter 3. Cells and structures involved in hair follicle regeneration: an introduction (Tsai J, Garza LA) -- Chapter 4. The dermal papilla and hair follicle regeneration: Engineering strategies to improve dermal papilla inductivity (Pantelireis N, Clavel C) -- Chapter 5. Dermal sheath and hair follicle regeneration (Yoshida Y, Tsuboi K, Kishimoto J) -- Chapter 6. Epithelial-mesenchymal interactions between hair follicles and dermal adipose tissue (Ramos R, Plikus MV) -- Chapter 7. Lymphatic vasculature and hair follicle regeneration (Cazorla A, Perez-Moreno M) -- Chapter 8. In vitro and ex vivo hair follicle models to explore therapeutic options for hair regeneration (Bertolini M, Piccini I, McElwee KJ) -- Chapter 9. Extracellular vesicles including exosomes for hair follicle regeneration (Aberdam E, le Riche A, Bordes S, Closs B, Park BS, Aberdam D) -- Chapter 10. Stem cell-based therapies for hair loss: what is the evidence from a clinical perspective? (Park BS, Choi HI) -- Chapter 11. Induced pluripotent stem cell approach for hair follicle regeneration (Pinto A, Terskikh AV) -- Chapter 12. Biofabrication technologies in hair neoformation (Abreu CM, Gasperini L, Marques AP) -- Chapter 13. Wound healing induced hair follicle regeneration (Jiang Y, Myung P) -- Chapter 14. Hair follicles in wound healing and skin remodeling (Plotczyk M, Jimenez F) .
    Kurzfassung: This book aims to comprehensively review the current cell-based strategies under investigation to achieve the regeneration of human hair follicles. The unique capacity of the human hair follicle to self-renew explains why this complex “mini-organ” has always attracted so much interest as a model for researchers to study stem cell biology and regenerative medicine. The hair follicle is considered a main reservoir of cutaneous stem cells, containing several pools of epithelial, melanocyte, and mesenchymal stem cells involved in hair follicle self-regeneration and pigmentation. In addition, while some of the different follicular cell types contribute to hair shaft growth, others participate in very important interfollicular functions such as dermal remodeling, re-epithelialization after wounding, and cutaneous stem cell homeostasis. The idea of human hair follicle regeneration either “de novo” or by activating dormant miniaturized follicles is not new, yet still continues to arouse enormous interest in the pursuit of a definitive cure for baldness. In contrast to hair follicle regeneration in mice, the attempts made with human follicles have been disappointing in terms of efficiency. However, recent advances in stem cell biology—as well as the appearance of new technologies like 3D printing—have revived expectations in this field of research. This book is divided into four sections. The first part includes an overview of the strategies used in hair follicle regeneration and a historical summary of the most important achievements to date. Parts two and three comprise the main body of the book, with detailed descriptions of the cells and tissue structures involved in hair follicle regeneration, followed by an elaboration of the different therapeutic strategies, engineering techniques, and a clinician’s perspective of stem cell-based therapies in hair loss treatments. Finally, the fourth part reviews the important contribution of the hair follicle in healing cutaneous wounds through the regeneration and remodeling of the dermis and epidermis after injury, as well as wound induced hair follicle neogenesis that occurs when the skin is injured.
    Materialart: Online-Ressource
    Seiten: XII, 307 p. 73 illus., 70 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030983314
    Serie: Stem Cell Biology and Regenerative Medicine, 72
    URL: https://doi.org/10.1007/978-3-030-98331-4
    DOI: 10.1007/978-3-030-98331-4
    DDC: 610.72
    Sprache: Englisch
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    Biomedical Translational Research : From Disease Diagnosis to Treatment (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical genetics. ; Diagnosis. ; Molecular biology. ; Cancer. ; Biomedical Research. ; Clinical Genetics. ; Diagnosis. ; Molecular Biology. ; Cancer Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Age-Rage Stress In The Pathophysiology Of Atherosclerosis And Its Treatment -- Chapter 2. Stem Cells In Dermatology: What The Future May Hold -- Chapter 3. Current Advances And Future Avenues In Endocrinology -- Chapter 4. Autologous Conditioned Serum In Lumbar And Cervical Radiculopathy: A Systematic Review -- Chapter 5. Bench To Bedside In Ophthalmology -- Chapter 6. Rapid Eye Movement In Sleep And Dream Sleep -- Chapter 7. Novel Cellular-Stress Models With Implications In Understanding And Treating Ent Pathologies -- Chapter 8. Respiratory Disorders : Contemporary Issues In 2020 -- Chapter 9. Discovery Of Hepatitis Viruses And Two Nobel Prizes : A Tale Of Observations Serendipity Collaboration Research Institute Inter Predated And Game Changing Innovation. Chapter 10. Conventional And Modern Approaches For Clinical And Laboratory Diagnosis Of Tuberculosis -- Chapter 11. Gut Microbes In Cardiovascular Diseases -- Chapter 12. Heart Failure – Future Perspectives -- Chapter 13. IL-10 : A Key Molecular In The Mitigation Of Heart Failure -- Chapter 14. Gene Therapy In Liver Disease : Challenges And Outcomes -- Chapter 15. Interrupting Crystal To Calculus Conversion : The Future Of Research In Urolithiasis -- Chapter 16. Stem Cells – Medical Marvel In Management Of Kidney Diseases -- Chapter 17. Deciphering The Code Of Male Infertility : Genetic Tests, Counselling And Molecular Basis Of Spermatogenic Failure -- Chapter 18. Translational Epidemiology In Cancer Research : The Less Travelled Path -- Chapter 19. Adenosine Pathway In Genitourinary Malignancies: A Promising Immunotherapeutic Target -- Chapter 20. Immune Checkpoint Inhibitors In Cancer Therapy: A Ray Of Hope -- Chapter 21. Recent Developments In The Immunotherapeutic Approaches For Cancer Treatment. Chapter 22. Thrombotic Complications In Women : Risks And Prevention -- Chapter 23. Biomedical Science And Women Health -- Chapter 24. Advances In The Role Of Macronutrients In Human Health And Diseases.
    Kurzfassung: The second volume of the Biomedical translational research discusses advancements in biomedical research for understanding the pathophysiology of various diseases towards improving diagnosis and treatment. It presents the integration of molecular-based technologies, clinical genomics, and medical informatics to improve diagnostic and treatment strategies. Further, the book reviews molecular genomics approaches for diagnosis and managing tuberculosis. It also covers the innovative strategies for cancer treatment through targeting metabolic pathways, tumor microenvironment, cancer stem cells, and immune cells. It also illuminates novel strategies for heart failure diagnosis and therapeutic approaches for the treatment of heart failure. It discusses improvements in translational research for discovery of new diagnostic tests, identifying novel biomarkers and drugable targets, and predicting optimal treatments based on understanding the underlying molecular basis of the disease. Lastly, it reviews the preclinical models of restenosis and their application and limitation in the evaluation of device-based interventional technologies for the treatment of coronary artery diseases.
    Materialart: Online-Ressource
    Seiten: XIV, 491 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811688454
    URL: https://doi.org/10.1007/978-981-16-8845-4
    DOI: 10.1007/978-981-16-8845-4
    DDC: 610.72
    Sprache: Englisch
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  • 77
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    Computational Methods for Precision Oncology (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Internal medicine. ; Bioinformatics. ; Biomedical Research. ; Internal Medicine. ; Bioinformatics.
    Beschreibung / Inhaltsverzeichnis: Part One: Basic Concepts in Precision Oncology -- Chapter 1. Design and Implementation of a precision oncology workflow -- Chapter 2. An overview of cancer genome sequencing -- Chapter 3. Software infrastructures for precision medicine workflows -- Part Two: Current Computational Methods and Tools in Precision Oncology -- Chapter 4. Somatic and germline variant calling from next-generation sequencing data -- Chapter 5. Identification of copy number alterations from next-generation sequencing data -- Chapter 6. Genome-wide discovery of large-scale structural variants from next-generation sequencing data -- Chapter 7. Assessment of microsatellite instability from next-generation sequencing data -- Chapter 8. Computational approaches for the investigation of intra-tumor heterogeneity and clonal evolution from bulk sequencing data -- Chapter 9. Analysis of the transcriptome for precision oncology applications -- Chapter 10. Computational methods for drug repurposing -- Chapter 11. Pathway for analysis for precision oncology applications -- Chapter 12. Identification of fusion transcripts from RNA-seq -- Chapter 13. Computational resources for the interpretation of variations in cancer -- Chapter 14. Analysis of electronic health records for precision oncology -- Chapter 15. Network approaches for precision oncology -- Chapter 16. Experimental validation of genomic alterations -- Part Three: Advanced Concepts - The Future of Precision Oncology -- Chapter 17. Molecular profiling of liquid biopsies for precision oncology -- Chapter 18. Artificial intelligence for precision oncology -- Chapter 19. Single-cell technologies in precision oncology -- Chapter 20. Computational approaches for precision immuno-oncology -- Chapter 21. Multi-pmics profiling of the tumor microenvironment -- Chapter 22. Epigenetic and precision oncology -- Chapter 23. Next generation knowledge bases to support precision oncology. .
    Kurzfassung: Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology.
    Materialart: Online-Ressource
    Seiten: XIV, 336 p. 36 illus., 26 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030918361
    Serie: Advances in Experimental Medicine and Biology, 1361
    URL: https://doi.org/10.1007/978-3-030-91836-1
    DOI: 10.1007/978-3-030-91836-1
    DDC: 610.72
    Sprache: Englisch
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  • 78
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    Online-Ressource
    The Immunogenetics of Dermatologic Diseases (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical genetics. ; Immunology. ; Dermatology. ; Biomedical Research. ; Medical Genetics. ; Immunology. ; Biomedical Research. ; Dermatology.
    Beschreibung / Inhaltsverzeichnis: Genetics control of immune responses -- Non-melanoma skin cancer -- Melanoma -- Psoriasis -- Atopic dermatitis -- Contact dermatitis -- Lichen planus -- Pemphigus and pemphigoids -- Morphea and Lichen Sclerosus -- Granuloma annulare and Necrobiosis lipoidica -- Alopecia areata -- Vitiligo -- Acne Vulgaris and Rosacea -- Urticaria and Angioedema -- Cutaneous drug reaction -- Photodermatologic disorders -- Infantile Haemangioma and other vascular malformations.
    Kurzfassung: This book intends to investigate the broad spectrum of genetic changes in immunological processes involved in cutaneous diseases. One of the main goals of immunogenetic studies is finding susceptibility genes for complex diseases. This can provide an insight into the pathogenesis of the condition in a way that is not easily achievable through other kinds of studies. Thus they are a rational initial step for generating hypotheses about disease pathogenesis. This may especially benefit dermatology, a field notorious for having too many diseases with unknown etiologies. Immunogenetic investigations have made targeted treatment strategies possible for diseases such as psoriasis and pemphigus. Even though these strategies have revolutionized the management of chronic dermatological conditions such as psoriasis, still there are a lot of unanswered questions. For instance, psoriasis patients respond very differently to each of the commercially available biological agents. This diversity could be partially explained by the differences in the sets of genes responsible for disease induction in each individual. Thus whole genome sequencing strategies, if feasible at individual levels, might help in tailoring these targeted treatments based on specific genetic backgrounds. Our intention in preparing this book was to explore the broad spectrum of the genetic aspects of immunological processes involved in cutaneous diseases. We have tried to cover most areas of dermatology where enough studies were available to gather a chapter. Still, there is a substantial lack of knowledge on the immunogenetics of many dermatological conditions. We hope that this book would encourage the investigators to fill these gaps of knowledge.
    Materialart: Online-Ressource
    Seiten: XXI, 450 p. 64 illus., 62 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030926168
    Serie: Advances in Experimental Medicine and Biology, 1367
    URL: https://doi.org/10.1007/978-3-030-92616-8
    DOI: 10.1007/978-3-030-92616-8
    DDC: 610.72
    Sprache: Englisch
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    Bone Tumors in Domestic Animals : Comparative Clinical Pathology (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Veterinary medicine. ; Agricultural genome mapping. ; Biomedical Research. ; Veterinary Science. ; Agricultural Genetics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Outline Of Anatomy/Physiology Of Skeletal Tissues -- Chapter 2: Tumors Of The Musculoskeletal System -- Chapter 3: Tumor-Like Lesions Of The Musculoskeletal System -- Chapter 4: General Considerations About Bone Tumors -- Chapter 5: Appendix: Manual For Histological Preparation And Examination Of Tissues Containing Bone And Cartilage.
    Kurzfassung: This book comparatively examines the etiopathogenetic, clinical-pathological, diagnostic and therapeutic strategies of the main bone tumors of domestic animals. The book also includes a description of the most significant aspects of macroscopic, microscopic, immunohistochemical, instrumental, diagnostic imaging and molecular biology aspects of spontaneous bone tumors in Veterinary Medicine, with also interspecies comparative aspects, including the human one. Last but not least, the book provides an overview of the new diagnostic and therapeutic frontiers related to the approach to animal bone tumors. The book serves as essential reading for professionals, researchers and students who work or want to tackle three paths in the field of comparative veterinary bone oncology.
    Materialart: Online-Ressource
    Seiten: XV, 193 p. 90 illus., 84 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030902100
    URL: https://doi.org/10.1007/978-3-030-90210-0
    DOI: 10.1007/978-3-030-90210-0
    DDC: 610.72
    Sprache: Englisch
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  • 80
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    BioSensing, Theranostics, and Medical Devices : From Laboratory to Point-of-Care Testing (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Nanobiotechnology. ; Biotechnology. ; Nanomedicine. ; Biomedical Research. ; Nanobiotechnology. ; Biotechnology. ; Nanomedicine and Nanotoxicology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1_Biosensing: Material, methods and principle of detection -- Chapter 2_Biosensing applications in the development of medical devices -- Chapter 3_Theranostics: basic principles -- Chapter 4_Material and technique advancements in the development of theranostic products -- Chapter 5_Medical device development strategies -- Chapter 6_Research aspects for the development of medical devices -- Chapter 7_Biosensor-based commercialized point-of-care devices -- Chapter 8_Medical devices in clinical set up -- Chapter 9_Clinical validation of medical devices -- Chapter 10_Regulatory steps involved in the validation of medical devices -- Chapter 11_Protocol for registration process of point-of-care device at FDA or equivalent agencies -- Chapter 12_Opportunities and challenges in medical device development -- Chapter 13_Prospective journey of the research idea from laboratory to the user in the clinic. .
    Kurzfassung: This book provides up-to-date information on the prototypes used to develop medical devices and explains the principles of biosensing and theranostics. It also discusses the development of biosensor and application-orientated design of medical devices. In addition to summarizing the clinical validation of the developed techniques and devices and the regulatory steps involved in their commercialization, the book highlights the latest research and translational technologies toward the development of point-of-care devices in the health care. Lastly, it explores the current opportunities, challenges and provides troubleshooting on the use of biosensors in precision medicine. The book is helpful for researchers and medical professionals working in the field of clinical theranostics, and medical-device development wanting to gain a better understanding into the principles and processes involved in the development of biosensors.
    Materialart: Online-Ressource
    Seiten: IX, 376 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811627828
    URL: https://doi.org/10.1007/978-981-16-2782-8
    DOI: 10.1007/978-981-16-2782-8
    DDC: 610.72
    Sprache: Englisch
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    Online-Ressource
    Invasive Diagnostics and Therapy (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Tumors Classification. ; Surgery. ; Cytokines. ; Virology. ; Biomedical Research. ; Cancer Staging. ; Surgery. ; Cytokines and Growth Factors. ; Virology.
    Beschreibung / Inhaltsverzeichnis: Compliance with the Surgery Safety Checklist: An Update on the Status -- Surgical Safety Checklist: Polychromatic or Achromatic Design -- Surgical Strategy and Clinical Outcome in Patients with Bronchial Carcinoids -- Frozen Section or Intraoperative Cytology: Are We Ready for a Paradigm Shift in Thoracic Surgery? -- Clinical Outcome in Patients with Nosocomial COVID-19 Infection After Thoracic Surgery -- Cytological Diagnostic Procedures in Malignant Mesothelioma -- Combination of Biochemical and Cytological Findings for Better Diagnosis in Pleural Effusions -- Cytokines in Renal Cell Carcinoma: A Step Towards Earlier Detection and Targeted Therapy -- Primary Hyperparathyroidism Secondary to Ectopic Parathyroid Adenoma: A Case Report -- Perception of Well-Being and Quality of Life in Obese Patients After Bariatric Surgery -- Do Multiple Brain Lesions Always Connote Worse Outcomes? Appraisal Evidence from a Tertiary Care Center in Koshi/Purbanchal Province of Nepal -- Radioimaging and Demographic Profiles of Patients with Spontaneous Intracerebral Hemorrhage: A Need for the Pragmatic Referral System -- Anticytokine Treatment of Rheumatoid Arthritis: An Observational Report.
    Kurzfassung: The book is an update on contentious or unsettled issues concerning invasive diagnostic and therapeutic challenges in cancer and related disorders, focusing on the surgical approach. Topics include recommendations for the best practice in using the surgery safety checklist, surgical strategies in a variety of thoracic cancers, renal cell carcinoma, tumors of parathyroid glands, mesothelioma, and bariatric surgeries. The focus is on the diagnostic and therapeutic challenges of aggressive cancerous entities, choosing the most beneficial modes for optimal outcomes and patient survival. Chapters also address radioimaging and therapy outcomes in different intracranial lesions leading to severe neurological disabilities. The areas of medical practice addressed are still veiled in uncertainty, yet-unresolved pathogenetic background, and have a substantial component of empirical rather than evidence-based clinical approach. Pursuing and sharing new ideas and innovations is essential for improving the management and outcome. The book endeavors to disseminate and deliberate on the latest medical knowledge, studies, and advancements in surgical and diagnostic dealing with cancer. The book is addressed to physicians and surgeons, and all allied health care professionals engaged in patient care and therapy.
    Materialart: Online-Ressource
    Seiten: VI, 119 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030988579
    Serie: Clinical and Experimental Biomedicine, 1374
    URL: https://doi.org/10.1007/978-3-030-98857-9
    DOI: 10.1007/978-3-030-98857-9
    DDC: 610.72
    Sprache: Englisch
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    Translational Informatics : Sports and Exercise Medicine (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Bioinformatics. ; Sports sciences. ; Medical informatics. ; Biomedical Research. ; Bioinformatics. ; Sport Science. ; Health Informatics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Ontologies and Knowledge Graphs for Exercise Medicine -- Chapter 2. Participatory exercise medicine and personalized healthcare -- Chapter 3. Integration of genetic and phenotyping data for sports medicine -- Chapter 4. Microbiota, sports and exercise medicine -- Chapter 5. Human immune system and exercise medicine: current process and future directions -- Chapter 6. Circadian Rhythm and Personalized Exercise -- Chapter 7. Data-driven Exercise Medicine for Cardiovascular Disease -- Chapter 8. Physical Activities and Prevention of Neurodegenerative Diseases -- Chapter 9. Exercise guidelines for cancer patients -- Chapter 10. Diabetes as a metabolic disease and translational exercise medicine informatics.
    Kurzfassung: The book provides readers the informatics and data-driven models for the discovery of personalized excise prescriptions applied to different cases. Overdiagnosis or over-treatment often happened since the complex interaction among the lifestyle, genetic, and environmental factors. Sports and exercise are reported efficient to prevent or reduce the risk of diseases, but the interactions between sports/exercise and disease are personalized and complex. Translational informatics is a powerful paradigm and it promotes the transfer of big data, knowledge and models to the precision application of sports to prevent diseases. Sports and exercise may have different effects on diverse diseases including cancers, neurodegenerative disease, and cardiovascular diseases, etc. This book covers many modern informatics models such as ontologies, knowledge graphs, blockchain, participatory medicine, semantic artificial intelligence, big data modeling, and so on. It also describes the challenges for the sports and exercise medical data sharing and standardization, the privacy protection of data as well as the integration of data from genomic level to physiological phenotype level. This book will be helpful to the readers who are interesting in sports and exercise medicine, healthcare, big data modeling, artificial intelligence in medicine and healthcare. .
    Materialart: Online-Ressource
    Seiten: IX, 234 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811691621
    URL: https://doi.org/10.1007/978-981-16-9162-1
    DOI: 10.1007/978-981-16-9162-1
    DDC: 610.72
    Sprache: Englisch
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    Biomarkers of Radiation in the Environment : Robust Tools for Risk Assessment (2022)
    Dordrecht :Springer Netherlands :
    Details
    Schlagwort(e): Biochemical markers. ; Radiation dosimetry. ; Environmental chemistry. ; Biochemistry. ; Biomarkers. ; Radiation Dosimetry and Protection . ; Environmental Chemistry. ; Biological Chemistry.
    Beschreibung / Inhaltsverzeichnis: TECHNIQUES FOR BIOMARKER DEVELOPMENT -- Chapter 1. Reducing Uncertainties In Live Monitoring Of Radiation In Wildlife -- Chapter 2. Synchrotron Light Facilities And Applications In Life Sciences -- Chapter 3. Elemental Imaging In Biology Using Synchrotron X-Ray Fluorescence Microscopy -- LOW-DOSE EFFECT MECHANISMS Chapter 4. Modelling Direct And Indirect Effects Of Radiation: Experimental, Clinical And Environmental Implications -- Chapter 5. Immune Networks In The Context Of Low Dose Ionizing Radiation -- Chapter 6. Learning From Nato Biomarker Research For Humans -- BIOMARKERS FOR RISK EVALUATION -- Chapter 7. Exosomes As Radiation Biomarkers -- Chapter 8. Monitoring Very Low Dose Radiation Damage In Dna Using “Field-Friendly” Biomarkers -- Chapter 9. The Development Of Bio-Assays Based On Non-Targeted Effects Of Radiation; A Potential Worm-Hole Into Ecosystem Level Biomarkers -- BIOMARKERS IN WILDLIFE Chapter 10. Birds As Bioindicators Of Radioactive Contamination And Its Effects -- Chapter 11. Amphibians In Field Radioecology: A Review And Perspective -- Chapter 12. Measuring Adaptive Responses Following Chronic And Low Dose Exposure In Amphibians -- Chapter 13. Are There Ecosystem-Relevant Endpoints For Measuring Radiation Impacts?.-Chapter 14. Biomarkers And Ecological Indicators For Environmental Radioactivity In Invertebrates.-BIOMARKER USE AND RESPONSES -- Environment, Workers And Public -- Chapter 16. Application Of The International System Of Radiation Protection In Fit-For-Purpose Assessment Of Impacts -- Chapter 17. Practicalities Of Mainstreaming Biomarker Use – A Canadian Perspective -- Index.
    Kurzfassung: This proceedings volume results from the NATO Advanced Research Workshop on 'Biomarkers of Radiation in the Environment: Robust Tools for Risk Assessment (BRITE)’. The BRITE workshop discussed insights from cancer research, epigenetics, non-human and human risk assessment, since many of the state-of-the-art biomarkers being developed for humans deserve consideration for environmental applications and vice versa. Sessions were very wide-ranging covering methods, mechanisms, cross disciplinary application and regulation. The chapters in this book have been grouped into five major themes that were covered by the BRITE workshop: · Techniques for biomarker development · Low-dose effect mechanisms · Biomarkers for risk evaluation · Biomarkers in wildlife · Biomarker use and responses Each chapter has been written independently and reflects the views of the chapter author(s). Therefore, the readers can form their own balanced view of the different perspectives on biomarkers of radiation in the environment. Given the breadth of topics covered and the state-of-the-art perspectives shared by leading experts in their respective fields, this book should form a valuable resource for anyone with an interest in how biomarkers can be used to improve our understanding of radiation in the environment and its potential impacts.
    Materialart: Online-Ressource
    Seiten: XVI, 330 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789402421019
    Serie: NATO Science for Peace and Security Series A: Chemistry and Biology,
    URL: https://doi.org/10.1007/978-94-024-2101-9
    DOI: 10.1007/978-94-024-2101-9
    DDC: 610.72
    Sprache: Englisch
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    From Malignant Transformation to Metastasis : Ion Transport in Tumor Biology (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Physiology.
    Beschreibung / Inhaltsverzeichnis: How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression -- Ion Channels, Transporters, and Sensors Interact with the Acidic Tumor Microenvironment to Modify Cancer Progression -- Role of pH Regulatory Proteins and Dysregulation of pH in Prostate Cancer -- Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues -- Circulating Tumor Cells: Does Ion Transport Contribute to Intravascular Survival, Adhesion, Extravasation, and Metastatic Organotropism?.
    Kurzfassung: How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression Line O. Elingaard-Larsen, Michala G. Rolver, Ester E. Sørensen, and Stine F. Pedersen Ion Channels, Transporters, and Sensors Interact with the Acidic Tumor Microenvironment to Modify Cancer Progression Ebbe Boedtkjer Role of pH Regulatory Proteins and Dysregulation of pH in Prostate Cancer Larry Fliegel Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues Giorgia Scarpellino, Luca Munaron, Anna Rita Cantelmo, and Alessandra Fiorio Pla Circulating Tumor Cells: Does Ion Transport Contribute to Intravascular Survival, Adhesion, Extravasation, and Metastatic Organotropism? Christian Stock.
    Materialart: Online-Ressource
    Seiten: XV, 175 p. 40 illus., 20 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030998004
    Serie: Reviews of Physiology, Biochemistry and Pharmacology, 182
    URL: https://doi.org/10.1007/978-3-030-99800-4
    DOI: 10.1007/978-3-030-99800-4
    DDC: 610.72
    Sprache: Englisch
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    A Roadmap to Successful Scientific Publishing : The Dos, the Don’ts and the Must-Knows (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical sciences. ; Vocational guidance. ; Career education. ; Biomedical Research. ; Health Sciences. ; Career Counseling. ; Career Skills.
    Beschreibung / Inhaltsverzeichnis: Part 1: Getting started -- Chapter 1: The why and the what of scientific research and publishing -- Chapter 2: Understanding research ethics -- Chapter 3: How to structure a scientific article, conference poster and presentation -- Part 2: The Hidden Bumps -- Chapter 4: Who gets authorship status? -- Chapter 5: The art of journal selection -- Chapter 6: Understanding the editor’s perspectives -- Part 3: The Destination -- Chapter 7: Converting a scientific article for the media -- Chapter 8: What are research metrics and why should I care? -- Chapter 9: Beyond your scientific publication -- Chapter 10: The Editor’s Perspective – Full-Length Interviews.
    Kurzfassung: In the age of "publish or perish," this book provides everything one needs to know about conducting research and successfully publishing it in a scientific journal. The reader learns about the complete process of scientific publishing: from selecting the most appropriate research design, to obtaining permissions and funding, to resourcefully presenting the research results in a poster and oral presentation. Additionally, the practical tips provided here help the reader formulate a compelling scientific article and choose the most suitable journal (subscription vs. the various open access modalities) for their publication. This book also addresses "invisible aspects" of scholarly publishing that are nonetheless important and that everyone should know and understand: avoiding predatory journals, understanding the editor's perspective, and becoming familiar with the various research metrics (from author to journal) that can all determine success or failure of a publication. Written in an informal style in which the author shares personal perspectives and experiences, the book is easily accessible to the reader. The book offers early career scientists in biomedicine and medicine a unique perspective on publishing research articles and how this process can enhance the authors' "scientific value" within the scientific ecosystem as well as their personal CVs.
    Materialart: Online-Ressource
    Seiten: XIV, 119 p. 25 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030992958
    URL: https://doi.org/10.1007/978-3-030-99295-8
    DOI: 10.1007/978-3-030-99295-8
    DDC: 610.72
    Sprache: Englisch
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    Integrative Clinical Research (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Pain medicine. ; Artificial intelligence. ; Biomedical Research. ; Pain Medicine. ; Artificial Intelligence.
    Beschreibung / Inhaltsverzeichnis: Artificial Intelligence and Precision Medicine: A Perspective -- Pedobarography in Physiotherapy: A Narrative Review on Current Knowledge -- Quantum Medicine: A Role of Extremely Low-Frequency Magnetic Fields in the Management of Chronic Pain -- Manual Therapy Approach to the Extraocular Muscles in Migraine Treatment: A Preliminary Study -- Capacitive and Resistive Electric Transfer Therapy: A Comparison of Operating Methods in Non-specific Chronic Low Back Pain -- Serum Impedance in Children with Recurrent Respiratory Infections -- Olfactory Response to Altitude Hypoxia: A Pilot Study During a Himalayan Trek -- The Impact of Change in Hospital Admissions When Primary Care Is Provided by a Single Primary Care Physician: A Cohort Study Among HMO Patients in Israel -- Risk of Falls in Patients Aged Over 65 in the Context of the Treatment Facility -- Anthropometric Indices as Long-Term Predictors of Diabetes in Impaired Fasting Glucose Metabolism: Findings in the PURE Study in Poland -- Cardiovascular Risk Factors Drive Impaired Fasting Glucose to Type 2 Diabetes: Findings After a 9-Year Follow-Up in the PURE Study in Poland -- Sleep-Disordered Breathing in Pregnancy.
    Kurzfassung: This book embraces a comprehensive range of research across several disciplines, providing insights and fresh perspectives on clinical topics, emphasizing the integrative medical approach. The book also addresses an increasing role of artificial intelligence in the development of clinical methodologies, research, and patient-oriented care. The authors share expertise and experience in rehabilitation medicine whose healing-effects particularly depend on the interaction between the therapist and patient. Chapters present novel approaches in manual rehabilitative therapy of common painful and disabling neuromuscular ailments, exemplified but not limited to low back pain and migraine. The myofascial trigger point release therapy includes specific manipulations to muscles and connective tissue which reduce pain. Other chapters address the issues of providing long-range medical care to older adults burdened with chronic diseases, notably hypoxia-related pathologies and their sequalae, pointing to the advantages of care provided by a single primary care physician. Changing paradigm of care is essential in chronic atherosclerosis-based diseases like cardiovascular disorders or diabetes. Chapters provide results of international cohort studies on predictive factors for the long-range progress of such ailments based on anthropometric and lifestyle indicators. The book aims to meet the increasing interest and importance to patients of integrative health therapies. Medical rehabilitation and lifestyle changes increasingly gain scientific support in difficult-to-treat chronic conditions and should be integrated in a controlled manner into conventional medicine. The book is addressed to physiotherapists, medical scientists and clinicians, and allied healthcare professionals.
    Materialart: Online-Ressource
    Seiten: VI, 109 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030996307
    Serie: Clinical and Experimental Biomedicine, 1375
    URL: https://doi.org/10.1007/978-3-030-99630-7
    DOI: 10.1007/978-3-030-99630-7
    DDC: 610.72
    Sprache: Englisch
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    Biomedical Visualisation : Volume 11 (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Education Data processing. ; Image processing Digital techniques. ; Computer vision. ; Anatomy. ; Biomedical engineering. ; Computer simulation. ; Biomedical Research. ; Computers and Education. ; Computer Imaging, Vision, Pattern Recognition and Graphics. ; Anatomy. ; Biomedical Engineering and Bioengineering. ; Computer Modelling.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Creating Interactive Three-Dimensional Applications to Visualise Novel Stent Grafts That Aid in the Treatment of Aortic Aneurysms -- Chapter 2. Using Confocal Microscopy to Generate an Accurate Vascular Model for Use in Patient Education Animation -- Chapter 3. Methods and applications of 3D Patient-Specific Virtual Reconstructions in Surgery -- Chapter 4. Proof of Concept for the Use of Immersive Virtual Reality in Upper Limb Rehabilitation of Multiple Sclerosis Patients -- Chapter 5. Virtual Wards: A Rapid Adaptation to Clinical Attachments in MBChB During the COVID-19 Pandemic -- Chapter 6. Artificial Intelligence: Innovation to Assist in the Identification of Sono-anatomy for Ultrasound-Guided Regional Anaesthesia -- Chapter 7. A Systematic Review of Randomised Control Trials Evaluating the Efficacy and Safety of Open and Endoscopic Carpal Tunnel Release -- Chapter 8. Exploring Visualisation for Embryology Education: A Twenty-First-Century Perspective -- Chapter 9. How Artificial Intelligence and Machine Learning Is Assisting Us to Extract Meaning from Data on Bone Mechanics? -- Chapter 10. Visual Communication and Creative Processes Within the Primary Care Consultation -- Chapter 11. Digital 2D, 2.5D and 3D Methods for Adding Photo-Realistic Textures to 3D Facial Depictions of People from the Past -- Chapter 12. Teaching with Cadavers Outside of the Dissection Room Using Cadaveric Videos -- Chapter 13. A Novel Cadaveric Embalming Technique for Enhancing Visualisation of Human Anatomy -- Chapter 14. Assessing the Impact of Interactive Educational Videos and Screencasts Within Pre-clinical Microanatomy and Medical Physiology Teaching.
    Kurzfassung: This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualisation techniques and technologies for the historical and forensic settings. The chapters presented in this volume cover such a diverse range of topics, with something for everyone. We present here chapters on 3D visualising novel stent grafts to aid treatment of aortic aneuryms; confocal microscopy constructed vascular models in patient education; 3D patient specific virtual reconstructions in surgery; virtual reality in upper limb rehabilitation in patients with multiple sclerosis and virtual clinical wards. In addition, we present chapters in artificial intelligence in ultrasound guided regional anaesthesia; carpal tunnel release visualisation techniques; visualising for embryology education and artificial intelligence data on bone mechanics. Finally we conclude with chapters on visualising patient communication in a general practice setting; digital facial depictions of people from the past; instructor made cadaveric videos, novel cadaveric techniques for enhancing visualisation of the human body and finally interactive educational videos and screencasts. This book explores the use of technologies from a range of fields to provide engaging and meaningful visual representations of the biomedical sciences. It is therefore an interesting read for researchers, developers and educators who want to learn how visualisation techniques can be used successfully for a variety of purposes, such as educating students or training staff, interacting with patients and biomedical procedures in general.
    Materialart: Online-Ressource
    Seiten: XVI, 343 p. 163 illus., 153 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030877798
    Serie: Advances in Experimental Medicine and Biology, 1356
    URL: https://doi.org/10.1007/978-3-030-87779-8
    DOI: 10.1007/978-3-030-87779-8
    DDC: 610.72
    Sprache: Englisch
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    Nanoscale Engineering of Biomaterials: Properties and Applications (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Medicine Research. ; Biology Research. ; Proteins. ; Biomaterials. ; Nanomedicine. ; Biomedical engineering. ; Biomedical Research. ; Biomaterials-Proteins. ; Nanomedicine and Nanotoxicology. ; Biomedical Engineering and Bioengineering.
    Beschreibung / Inhaltsverzeichnis: Part 1 -- 1 Interactions between the physiological environment and titanium-based implant materials – from understanding to control -- 2 Nanoscale surface Engineering and Characterization of Biomaterial -- 3 Progress of Nanotechnology-based Detection and Treatment of Alzheimer’s Disease Biomarkers -- 4 Biomaterials: Types and Applications -- Part 2 -- 5 Additive Manufacturing of Ti and its alloy-based Bioimplants for Orthopaedic Applications -- 6 Physico-chemical Modifications of Magnesium and Alloys for Biomedical Applications -- 7 Metallic Foams in Bone Tissue Engineering -- 8 Surface modification of metallic biomaterials for cardiovascular cells regulation and biocompatibility improvement -- 9 Advancement of spinel ferrites for biomedical application -- Part 3 -- 10 Functionalized 3D bioactive polymeric materials in tissue engineering and regenerative medicine -- 11 Polymer matrixes used in wound healing applications. 12 Conductive Polymers for Cardiovascular Applications -- 13 Engineered polymeric materials/nanomaterials for growth factor/drug delivery in bone tissue engineering applications -- 14 Surface engineering of polymeric materials for bone tissue engineering -- 15 Antibacterial Surface Modification to Prevent Biofilm Formation on Polymeric Biomaterials -- 16 Polymer Surface Engineering in the Food Packaging Industry -- 17 Polymeric Membranes in Waste-water Treatment -- 18 Functionalized Fluoropolymer Membrane for Fuel Cell Applications -- Part 4 -- 19 Bioceramics for Biomedical Applications -- 20 Applications of nanomaterials in the textile industry -- 21 Properties and characterization of advanced composite materials -- 22 Properties and characterization of advanced composite materials -- 23 Nano composites application in sewage treatment and degradation of persistent pesticides used in agriculture -- 24 Biomimetic Mineralization of Electrospun PCL based Composite Nanofibrous Scaffold for hard tissue Engineering. .
    Kurzfassung: This book provides a comprehensive overview of the latest advances in a wide range of biomaterials for the development of smart and advanced functional materials. It discusses the fundamentals of bio-interfacial interactions and the surface engineering of emerging biomaterials like metals and alloys, polymers, ceramics, and composites/nanocomposites. In turn, the book addresses the latest techniques and approaches to engineering material surfaces/interfaces in, e.g., implants, tissue engineering, drug delivery, antifouling, and dentistry. Lastly, it summarizes various challenges in the design and development of novel biomaterials. Given its scope, it offers a valuable source of information for students, academics, physicians and particularly researchers from diverse disciplines such as material science and engineering, polymer engineering, biotechnology, bioengineering, chemistry, chemical engineering, nanotechnology, and biomedical engineering for various commercial and scientific applications.
    Materialart: Online-Ressource
    Seiten: X, 704 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811636677
    URL: https://doi.org/10.1007/978-981-16-3667-7
    DOI: 10.1007/978-981-16-3667-7
    DDC: 610.72
    Sprache: Englisch
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    Geospatial Data Science in Healthcare for Society 5.0 (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Geographic information systems. ; Quantitative research. ; Artificial intelligence. ; Medical care. ; Geographical Information System. ; Data Analysis and Big Data. ; Artificial Intelligence. ; Health Care.
    Beschreibung / Inhaltsverzeichnis: Potential of Geospatial Data in Healthcare for Society 5.0 -- Geospatial Health Data Analytics for Society 5.0 -- Relevance of spatio-temporal data visualisation techniques in healthcare system -- GIS and Remote Sensing for public health -- Infectious diseases and their tracking in GIS.
    Kurzfassung: The book introduces a variety of latest techniques designed to represent, enhance, and empower multi-disciplinary approaches of geographic information system (GIS), artificial intelligence (AI), deep learning (DL), machine learning, and cloud computing research in healthcare. It provides a unique compendium of the current and emerging use of geospatial data for healthcare and reflects the diversity, complexity, and depth and breadth of this multi-disciplinary area. This book addresses various aspects of how smart healthcare devices can be used to detect and analyze diseases. Further, it describes various tools and techniques to evaluate the efficacy, suitability, and efficiency of geospatial data for health-related applications. It features illustrative case studies, including future applications and healthcare challenges. This book is beneficial for computer science and engineering students and researchers, medical professionals, and anyone interested in using geospatial data in healthcare. It is also intended for experts, offering them a valuable retrospective and a global vision for the future, as well as for non-experts who are curious to learn about this important subject. The book presents an effort to draw how we can build health-related applications using geospatial big data and their subsequent analysis.
    Materialart: Online-Ressource
    Seiten: VIII, 318 p. 116 illus., 73 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811694769
    Serie: Disruptive Technologies and Digital Transformations for Society 5.0,
    URL: https://doi.org/10.1007/978-981-16-9476-9
    DOI: 10.1007/978-981-16-9476-9
    DDC: 910.285
    Sprache: Englisch
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    Geospatial Technology for Human Well-Being and Health (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Geographic information systems. ; Environmental geography. ; Public health. ; Big data. ; Epidemiology. ; Geographical Information System. ; Integrated Geography. ; Public Health. ; Big Data. ; Epidemiology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1-Building the analytic toolbox-from spatial analytics to spatial statistical inference with geospatial data -- Chapter 2-Spatial data integration to better represent pollutants for environmental health studies -- Chapter 3-Spatial health data analysis-data driven and model driven approaches. Chapter 4 -- Machine learning, big data and spatial tools-a combination to reveal complex facts that impact environmental health -- Chapter 5-Spatial aspects of seasonality and infectious diseases -- Chapter 6-Earth observation data and technology to model influenza epidemiology -- Chapter 7-Trend of geospatial technology in environmental health application-from public health to individual healthcare -- Chapter 8-Geospatial technology to analyze human well-being and its eco-social determinants -- Chapter 9-Spatial components of population health -- Chapter 10-Geospatial technology in medical geology -- Chapter 11-Geospatial technology in planning and operations of telehealth programs -- Chapter 12-Integrating GIS, toxicology, microbiology and geochemistry-a multidisciplinary integrated approach for better understanding the public health issues.
    Kurzfassung: Over the last thirty years or so, there have been tremendous advancements in the area of geospatial health; however, somehow, two aspects have not received as much attention as they should have received. These are a) limitations of different spatial analytical tools and b) progress in making geospatial environmental exposure data available for advanced health science research and for medical practice. This edited volume addresses those two less explored areas of geospatial health with augmented discussions on the theories, methodologies and limitations of contemporary geospatial technologies in a wide range of applications related to human well-being and health. In 20 chapters, readers are presented with an up-to-date assessment of geospatial technologies with an emphasis on understanding general geospatial principles and methodologies that are often overlooked in the research literature. As a result, this book will be of interest to both newcomers and experts in geospatial analysis and will appeal to students and researchers engaged in studying human well-being and health. Chapters are presenting new concepts, new analytical methods and contemporary applications within the framework of geospatial applications in human well-being and health. The topics addressed by the various chapter authors include analytical approaches, newer areas of geospatial health application, introduction to unique resources, geospatial modeling, and environmental pollution assessments for air, water and soil. Although geospatial experts are expected to be the primary readers, this book is designed in such a way so that the public health professionals, environmental health scientists and clinicians also find it useful with or without any familiarity with geospatial analysis.
    Materialart: Online-Ressource
    Seiten: XVIII, 417 p. 141 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030713775
    URL: https://doi.org/10.1007/978-3-030-71377-5
    DOI: 10.1007/978-3-030-71377-5
    DDC: 910.285
    Sprache: Englisch
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    Metrics That Make a Difference : How to Analyze Change and Error (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Statistics . ; Computer science Mathematics. ; Mathematical statistics. ; Functions of complex variables. ; Algorithms. ; Geographical Information System. ; Statistics in Engineering, Physics, Computer Science, Chemistry and Earth Sciences. ; Probability and Statistics in Computer Science. ; Several Complex Variables and Analytic Spaces. ; Algorithms.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Binary Variable Versus Binary Variable -- Chapter 2: Binary Variable Versus Rank Variable -- Chapter 3: Application of the Total Operating Characteristic -- Chapter 4: Categorical Variable Versus Categorical Variable -- Chapter 5: Application to Categorical Error Assessment with Sampling -- Chapter 6: Multiple Spatial Resolutions for Categorical Variables -- Chapter 7: Application to Categorical Temporal Change -- Chapter 8: Interval Variable Versus Interval Variable -- Chapter 9: Application to Interval Temporal Change -- Chapter 10: Indices of Agreement -- Chapter 11: Vector Variable Versus Vector Variable -- Chapter 12: Commandments to Avoid Deadly Sins.
    Kurzfassung: Your government warns that 10% of your neighbors have a deadly contagious virus. The producer of a diagnostic test advertises that 90% of its tests are correct for any population. The test indicates that you have the virus. This book’s author claims your test has a 50% chance of being false, given your test’s result. Who do you believe? This book gives you insights necessary to interpret metrics that make a difference in life’s decisions. This book gives methods and software that are essential to analyse change and error. Change describes a phenomenon across time points. Error compares diagnoses with the truth. Other texts give insufficient attention to these topics. This book’s novel ideas dispel popular misconceptions and replace previous methods. The author uses carefully designed graphics and high school mathematics to communicate easily with college students and advanced scientists. Applications include but are not limited to Remote Sensing, Land Change Science, and Geographic Information Science. “A wide range of tools to aid understanding of land cover and its change has been used but scientific progress has sometimes been limited through misuse and misunderstanding. Professor Pontius seeks to rectify this situation by providing a book to accompany the researcher’s toolbox. Metrics That Make a Difference addresses basic issues of relevance to a broad community in a mathematically friendly way and should greatly enhance the ability to elicit correct information. I wish this book existed while I was a grad student.” – Giles Foody, Professor of Geographical Information Science, The University of Nottingham “Metrics That Make a Difference provides a comprehensive synthesis of over two decades of work during which Dr. Pontius researched, developed, and applied these metrics. The book meticulously and successfully guides the reader through the conceptual basis, computations, and proper interpretation of the many metrics derived for different types of variables. The book is not just a mathematical treatise but includes practical guidance to good data analysis and good science. Data scientists from many fields of endeavor will benefit substantially from Dr. Pontius’ articulate review of traditionally used metrics and his presentation of the innovative and novel metrics he has developed. While reading this book, I had multiple ‘aha’ moments about metrics that I shouldn't be using and metrics that I should be using instead.” – Stephen Stehman, Distinguished Teaching Professor, State University of New York.
    Materialart: Online-Ressource
    Seiten: XXI, 117 p. 17 illus., 16 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030707651
    Serie: Advances in Geographic Information Science,
    URL: https://doi.org/10.1007/978-3-030-70765-1
    DOI: 10.1007/978-3-030-70765-1
    DDC: 910.285
    Sprache: Englisch
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  • 92
    Online-Ressource
    Online-Ressource
    Remote Sensing Land Surface Changes : The 1981-2020 Intensive Global Warming (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Environmental monitoring. ; Physical geography. ; Environment. ; Geographical Information System. ; Environmental Monitoring. ; Earth System Sciences. ; Environmental Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter 1-Why this Topic? -- Chapter 2-Global Warming Impact on Earth Systems -- Chapter 3-The IPCC Reports on Global Warming and Land Changes -- Chapter 4.NOAA Operational Environmental Satellites for Earth Monitoring -- Chapter 5-New Remote Sensing Vegetation Health Technology -- Chapter 6-Cause of Climate Warming -- Chapter 7- Land Cover Changes from Intensive Climate Warming -- Chapter 8-Global Warming Crop Yield and Food Security -- Chapter 9-Remote Sensing Malaria During Global Warming -- Chapter 10-Malaria Performance Trend During 1981-2022 -- Chapter 11-Remote Sensing Drought Watch and Food Security -- Chapter 12-Has Drought Intensified During 1981-2021 Global Warming?
    Kurzfassung: This book discusses the detrimental consequences of climate-related land changes over a 40-year period between 1981 and 2020, and focuses on how climate warming is deteriorating the agricultural system due to excessive heat, lack of moisture and more intensive and widespread droughts leading to a reduction of agricultural production. Most of the existing literature on the unfavourable consequences of global warming for land are based on a relatively short period of weather station data, covering local land areas with limited networks and monitoring parameters. These concerns have led to the use of satellite data, whose measurements are controlled by such vegetation characteristics as chlorophyll, carotenoids, moisture contents in the plants and temperature inside the vegetation community. Therefore, the discussion of this book is completely based on high-resolution global land surface measurements by the sensors on the National Oceanic and Atmospheric Administration’s (NOAA) operational afternoon polar-orbiting satellites. The book also focuses on understanding climate change impacts on land changes where humans are living, and combines biophysically-grounded methods and the 40-year data to develop models for monitoring large-scale Earth warming impacts on land and for timely prediction of climate consequences for humans. These 40-year trends in land characteristics will help to better inform the assessment of potential changes in the future and how to reach human sustainability. The book will of interest to scientists using satellite remote sensing to track climate change impacts on land over time, as well as students and researchers in climatology and environmental sustainability. .
    Materialart: Online-Ressource
    Seiten: IX, 462 p. 159 illus., 126 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030968106
    URL: https://doi.org/10.1007/978-3-030-96810-6
    DOI: 10.1007/978-3-030-96810-6
    DDC: 910.285
    Sprache: Englisch
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  • 93
    Online-Ressource
    Online-Ressource
    Remote Sensing Intelligent Interpretation for Mine Geological Environment : From Land Use and Land Cover Perspective (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Geographic information systems. ; Machine learning. ; Signal processing. ; Geology. ; Environmental monitoring. ; Geographical Information System. ; Machine Learning. ; Signal, Speech and Image Processing . ; Geology. ; Environmental Monitoring.
    Beschreibung / Inhaltsverzeichnis: Preface.-Mine geological environment: An overview.-Multimodal remote sensing science and technology.-Deep learning technology for remote sensing intelligent interpretation.-Remote sensing interpretation signs of mine land occupation type -- Mine remote sensing dataset construction for multi-level tasks -- Mine target detection by remote sensing and deep learning -- Mine remote sensing scene classification by deep learning -- Mine land occupation classification based on machine learning and remote sensing images -- Mine land occupation classification based on deep learning and remote sensing images -- Concluding remarks.
    Kurzfassung: This book examines the theory and methods of remote sensing intelligent interpretation based on deep learning. Based on geological and environmental effects on mines, this book constructs a set of systematic mine remote sensing datasets focusing on the multi-level task with the system of “target detection→scene classification→semantic segmentation." Taking China’s Hubei Province as an example, this book focuses on the following four aspects: 1. Development of a multiscale remote sensing dataset of the mining area, including mine target remote sensing dataset, mine (including non-mine areas) remote sensing scene dataset, and semantic segmentation remote sensing dataset of mining land cover. The three datasets are the basis of intelligent interpretation based on deep learning. 2. Research on mine target remote sensing detection method based on deep learning. 3. Research on remote sensing scene classification method of mine and non-mine areas based on deep learning. 4. Research on the fine-scale classification method of mining land cover based on semantic segmentation. The book is a valuable reference both for scholars, practitioners and as well as graduate students who are interested in mining environment research.
    Materialart: Online-Ressource
    Seiten: XII, 246 p. 110 illus., 89 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811937392
    URL: https://doi.org/10.1007/978-981-19-3739-2
    DOI: 10.1007/978-981-19-3739-2
    DDC: 910.285
    Sprache: Englisch
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  • 94
    Online-Ressource
    Online-Ressource
    A Geographer's Guide to Computing Fundamentals : Python in ArcGIS Pro (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geographic information systems. ; Geography. ; Computer programming. ; Geographical Information System. ; Geography. ; Programming Techniques.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to Scripting and Programming -- Chapter 2. Basics of programming—Variables, Operators, & Statements -- Chapter 3. Basics of programming—Control Structures -- Chapter 4. Basics of programming—Functions and Objects -- Chapter 5. Reading a Python Script -- Chapter 6. Debugging -- Chapter 7. Introduction to ArcPy -- Chapter 8. Basics of accessing data in ArcGIS -- Chapter 9. Rasters -- Chapter 10. Tables and Cursors -- Chapter 11. Vectors and Geometries -- Chapter 12. Mapping--symbologies -- Chapter 13. Mapping—layouts -- Chapter 14. Creating custom tools -- Chapter 15. Error Handling -- Chapter 16. Creating Custom Classes -- Chapter 17. Putting it all together -- Chapter 18. ArcPy for Web GIS using ArcGIS Online -- Chapter 19. Incorporating External Packages -- Chapter 20. Using Multiple Python Files -- Chapter 21. Developing a Custom Python Package.
    Kurzfassung: This upper-undergraduate textbook teaches students programming in GIS using a mix of computer science theory and hands-on activities, with the aim of empowering students to understand fundamentals and apply their knowledge beyond the specific examples in the book. Each of the book’s twenty-one chapters integrates instructional material with exercises in ArcGIS Pro. In doing so, this book combines the strengths of workbooks and theoretical textbooks to provide a holistic and comprehensive text. Each chapter concludes with an unguided task that ensures students have learned the broader principles explained therein. In addition to its unique format, the book covers oft-neglected topics such as debugging, creating a program from scratch, and managing metadata. Section I starts with the principles of scripting and programming with Python. Section II introduces the ArcPy module and elements specific to ArcGIS Pro. This section focuses on data structures, and how they are used and implemented within Python. Section III uses the topic of algorithms to guide the student through creating tools to add functionality to ArcGIS Pro. The last section, Section IV, builds upon section III to guide the student to developing and sharing projects and Python packages to include external open-source code and share the Python code as an open-source package. This text will prepare students for a long-term ability to do GIS programming, whether in industry or academic research. This comes from the author’s observations of students who have learned GIS programming in one platform, such as VBA in ArcMap, struggle to apply that knowledge to a new platform, such as Python in ArcGIS Pro, because the content was presented too closely with a specific platform. The integration of exercises with conceptual content, along with the choice of chapter content, serves this goal of preparing students for working in a dynamic, rapidly changing technology field.
    Materialart: Online-Ressource
    Seiten: XII, 267 p. 110 illus., 88 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031084980
    Serie: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-031-08498-0
    DOI: 10.1007/978-3-031-08498-0
    DDC: 910.285
    Sprache: Englisch
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  • 95
    Online-Ressource
    Online-Ressource
    Trends of Artificial Intelligence and Big Data for E-Health (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Medical care. ; Quantitative research. ; Artificial intelligence Data processing. ; Health services administration. ; Bioinformatics. ; Biomedical Research. ; Health Care. ; Data Analysis and Big Data. ; Data Science. ; Health Care Management. ; Bioinformatics.
    Beschreibung / Inhaltsverzeichnis: 1. AI and Big Data for Intelligent Health: Promise and Potential -- 2. AI and Big Data for Cancer Segmentation, Detection and Prevention -- 3. Radiology, AI and Big Data: Challenges and Opportunities for Medical Imaging -- 4. Neuroradiology: Current Status and Future Prospects -- 5. Big Data and AI in Cardiac Imaging -- 6. Artificial Intelligence and Big data for COVID-19 Diagnosis -- 7. AI and Big Data for Drug Discovery -- 8. Blockchain of IoMT (BIoMT): A New Paradigm for COVID-19 Pandemic: Application, Architecture, Technology, and Security -- 9. AI and Big Data for Therapeutic Strategies in Psychiatry -- 10. Distributed Learning in Healthcare -- 11. Cybersecurity in Healthcare -- 12. Radiology and Radiomics: Towards oncology Prediction with IA and Big Data.
    Kurzfassung: This book aims to present the impact of Artificial Intelligence (AI) and Big Data in healthcare for medical decision making and data analysis in myriad fields including Radiology, Radiomics, Radiogenomics, Oncology, Pharmacology, COVID-19 prognosis, Cardiac imaging, Neuroradiology, Psychiatry and others. This will include topics such as Artificial Intelligence of Thing (AIOT), Explainable Artificial Intelligence (XAI), Distributed learning, Blockchain of Internet of Things (BIOT), Cybersecurity, and Internet of (Medical) Things (IoTs). Healthcare providers will learn how to leverage Big Data analytics and AI as methodology for accurate analysis based on their clinical data repositories and clinical decision support. The capacity to recognize patterns and transform large amounts of data into usable information for precision medicine assists healthcare professionals in achieving these objectives. Intelligent Health has the potential to monitor patients at risk with underlying conditions and track their progress during therapy. Some of the greatest challenges in using these technologies are based on legal and ethical concerns of using medical data and adequately representing and servicing disparate patient populations. One major potential benefit of this technology is to make health systems more sustainable and standardized. Privacy and data security, establishing protocols, appropriate governance, and improving technologies will be among the crucial priorities for Digital Transformation in Healthcare.
    Materialart: Online-Ressource
    Seiten: X, 251 p. 67 illus., 64 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031111990
    Serie: Integrated Science, 9
    URL: https://doi.org/10.1007/978-3-031-11199-0
    DOI: 10.1007/978-3-031-11199-0
    DDC: 610.72
    Sprache: Englisch
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  • 96
    Online-Ressource
    Online-Ressource
    Engineering Biomaterials for Neural Applications (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biomedical engineering. ; Neurosciences. ; Biotechnology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Biomedical Devices and Instrumentation. ; Neuroscience. ; Biotechnology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Scaffolds for promoting neural repair -- Chapter 2. Composites for nerve regeneration -- Chapter 3. Configurable models of the blood-brain barrier -- Chapter 4. Engineering nerve conduits -- Chapter 5. Flexible electronics for stem cell differentiation -- Chapter 6. Nanosensors for brain chemistry -- Chapter 7. Nanomaterials for imaging the brain ECS -- Chapter 8. Microfluidics for analysis of neuronal development -- Chapter 9. Multiple particle tracking measurements of extracellular matrix dysregulation -- Chapter 10. Bioresponsive nanomaterials for treatment of CNS disease -- Chapter 11. Redox regulation for controlling cell fate -- Chapter 12. Polymersome delivery of CRISPR-based therapies -- Chapter 13. Multifunctional polymers for targeted delivery -- Chapter 14. Theranostic nanomaterials for brain injury.
    Kurzfassung: This contributed volume explores the ways in which researchers engineer new biomaterials for the challenging problems of the peripheral and central nervous systems. These biomaterials are uniquely positioned for use in creating in vitro models of injury and disease, testing therapeutic treatments, understanding neural development, and mapping the multi-scalar environment of the brain. This book informs readers from biology, chemistry, materials science, engineering, and neuroscience on cutting edge research in engineering technologies, from fundamental material development through pre-clinical studies. The book also highlights target applications in three areas of research: (1) engineering neural models and materials, (2) probing biological underpinnings of neurological function and disease, and (3) designing therapeutic and diagnostic treatments for neurological disease. .
    Materialart: Online-Ressource
    Seiten: VIII, 353 p. 64 illus., 61 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031114090
    URL: https://doi.org/10.1007/978-3-031-11409-0
    DOI: 10.1007/978-3-031-11409-0
    DDC: 610.72
    Sprache: Englisch
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  • 97
    Online-Ressource
    Online-Ressource
    Principles of Light Microscopy: From Basic to Advanced (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Life sciences. ; Cytology. ; Spectrum analysis. ; Biomedical Research. ; Life Sciences. ; Cell Biology. ; Spectroscopy.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. The physical principles of light propagation and light-matter interactions -- Chapter 2. Design, alignment and usage of infinity-corrected microscope -- Chapter 3. Epifluorescence Microscopy -- Chapter 4. Basic digital image design, processing, analysis, management, and presentation -- Chapter 5. Confocal Microscopy -- Chapter 6. Live-cell Imaging: A Balancing Act Between Speed, Sensitivity and Resolution -- Chapter 7. Structured Illumination Microscopy -- Chapter 8. Stimulated Emission Depletion Microscopy -- Chapter 9. Two-Photon Imaging -- Chapter 10. Modern microscopy image analysis: quantifying colocalization on a mobile device -- Chapter 11. Spinning Disk Microscopy -- Chapter 12. Light Sheet Fluorescence Microscopy -- Chapter 13. Localization microscopy: a review of the progress in methods and applications.
    Kurzfassung: This textbook is an excellent guide to microscopy for students and scientists, who use microscopy as one of their primary research and analysis tool in the laboratory. The book covers key microscopy principles and explains the various techniques such as epifluorescence microscopy, confocal/live cell imaging, SIM/light sheet microscopy, and many more. Easy-to-understand protocols provide helpful guidance for practical implementation in various commercially available imaging systems. The reader is introduced to histology and further be guided through advanced image acquisition, classification and analysis. The book is written by experienced imaging specialists from the UK, other EU countries, the US and Asia, and is based on advanced training courses for master students and PhD students. Readers are not expected to be familiar with imaging and microscopy technologies, but are introduced to the subject step by step. This textbook is indented for biomedical and medical students, as well as scientists and postdocs who want to acquire a thorough knowledge of microscopy, or gain a comprehensive overview of modern microscopy techniques used in various research laboratories and imaging facilities. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Materialart: Online-Ressource
    Seiten: VIII, 324 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031044779
    URL: https://doi.org/10.1007/978-3-031-04477-9
    DOI: 10.1007/978-3-031-04477-9
    DDC: 610.72
    Sprache: Englisch
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  • 98
    Online-Ressource
    Online-Ressource
    Fundamentals and Advances in Medical Biotechnology (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Biomedical engineering. ; Biotechnology. ; Molecular biology. ; Nanotechnology. ; Bioethics. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Biotechnology. ; Molecular Biology. ; Nanotechnology. ; Bioethics.
    Beschreibung / Inhaltsverzeichnis: The advent of Medical Biotechnology -- Biotechnology in Medicine: Fundamentals -- Biotechnology in Medicine: Advances-I -- Biotechnology in Medicine: Advances-II -- Analytical Techniques in Medical Biotechnology -- Immunology in Medical Biotechnology -- Epigenetics and Medical Biotechnology -- Stem Cell Technology in Medical Biotechnology -- Pharmaceutical Biotechnology -- Diagnostic and Therapeutic Biotechnology -- Nanotechnology and Nanomedicine -- Laboratory Protocols in Medical Biotechnology-I -- Laboratory Protocols in Medical Biotechnology-II -- Ethics and Medical Biotechnology -- Career and opportunities in Medical Biotechnology -- Index.
    Kurzfassung: This book serves as an introduction to the concepts of medical biotechnology, with great details about fundamentals and early disciplines of study as well as emerging fields and the latest research. The book follows a chronological order from the earliest discoveries and breakthroughs of medical biotechnology to the latest areas of study. The book contains up-to-date citations for each chapter and section, which makes it easy for the reader to understand the concept and also to follow the latest developments in the particular area. It is an ideal book for undergraduate and graduate students who aspire to derive basic knowledge and are also keen on learning about the latest advancements in the field of medical biotechnology. .
    Materialart: Online-Ressource
    Seiten: XII, 459 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030985547
    URL: https://doi.org/10.1007/978-3-030-98554-7
    DOI: 10.1007/978-3-030-98554-7
    DDC: 610.72
    Sprache: Englisch
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  • 99
    Online-Ressource
    Online-Ressource
    Multidisciplinarity and Interdisciplinarity in Health (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Neurosciences. ; Public health. ; Bioethics. ; Clinical medicine Research. ; Biomedical Research. ; Neuroscience. ; Public Health. ; Bioethics. ; Clinical Research.
    Beschreibung / Inhaltsverzeichnis: Introduction on Integrated Science: Multidisciplinarity and Interdisciplinarity in Health -- Cognitive Sciences as a Naturalistic Model of Interdisciplinary Approaches -- The Aesthetics of Science from the Viewpoint of Neuroscience -- Neuroscience and Quantum Physics Aspect of Human Brainwaves -- Modern Psychiatry: Confluence of Mind, Science, and Society -- Schizophrenia: A Disorder of Timing and Sensorimotor Integration during Decision-making -- Getting to Know Ourselves Through Recognizing Ourselves in Others: Neuroanatomy of Empathy in a Social Neuroscientific Model -- Why People Make Irrational Choices About Their Health? -- Adherence to Treatment: At the Interface of Biological, Medical, and Social Sciences -- Social Cognition and Food Decisions in Obesity -- Nuclear Medicine: A Transdisciplinary Field to Integrate Formal, Physical, Biological, and Medical Sciences -- Beyond the Borders of Dentistry: Interprofessional and Interdisciplinary Approach to Oral Health Promotion -- Drug Discovery in Big Pharma: Where “Birds” and “Fish” Collaborate to Find New Medicines -- A Phenomenological Analysis of the Pandemic: Philosophy and Life -- Engineering, Environment, and Health: Why interdisciplinarity matters? -- Super-spreading in Infectious Diseases: A Global Challenge for All Disciplines -- Possibility of Changes in Travel Behavior as a Consequence of the Pandemic and Teleworking -- Bringing the Two Cultures of the Arts and Sciences Together in Complex Health Interventions -- Thinking Deeper, Wider, Further: Visual Thinking for the Pandemic 3.0 and the Game-Changing Pathways ahead -- The Clinical Benefits of Art Therapy: Definition, History, and Outcomes with a Focus on Music Therapy -- When Combining Arts and Sciences Assists Medical Devices Uses: DeafSpace and Cochlear Implants -- Art, Medicine, and Public Health: Synergizing Humanistic and Medical Strategies in Managing a Pandemic -- Big Data and Artificial Intelligence for E-Health -- Artificial Intelligence in the Medical Context: Who Is the Agent in Charge? -- Ethical Deliberation on AI-Based Medicine -- Towards an Integrative and Holistic Approach to the Discipline of Health Informatics -- Integrated, Multidisciplinary, and Interdisciplinary Medical Education -- Giving Voice to Social Values in Achieving Universal Health Coverage -- Discrimination in Medical Research Sampling: Recommendations and Applications to Psychology -- Integrated Science 2050: Multidisciplinarity and Interdisciplinarity in Health.
    Kurzfassung: The contributed volume "Multidisciplinarity and Interdisciplinarity in Health" is a health-centered volume of the Integrated Science Book series. Lack of confidence, lack of expertise, complexities of healthcare, the confusing nature of healthcare environments, and lack of organization and standardization can become obstacles to successful communication. This volume establishes how extensive is the interface between formal sciences and medical sciences on health-related issues. The book provides an overview of the value of the integration of formal, biological, and medical sciences and related products, i.e., health informatics and biomedical engineering, to frame a holistic approach to health systems, healthcare, medical practice, drug discovery, and medical device design. The book also focuses on innovative solutions to the most critical issues of different health crisis, including obesity, infectious outbreaks, and cancer that can be found by using an integrative approach. It also contains the fascinating crossroads between medical sciences, physics, and mind that is discussed from multiple perspectives on cognition, neuroscience, and psychiatry. These multidisciplinary considerations will expand the concepts of creativity, leadership, aesthetics, empathy and mental health. .
    Materialart: Online-Ressource
    Seiten: XVI, 729 p. 168 illus., 138 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030968144
    Serie: Integrated Science, 6
    URL: https://doi.org/10.1007/978-3-030-96814-4
    DOI: 10.1007/978-3-030-96814-4
    DDC: 610.72
    Sprache: Englisch
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  • 100
    Online-Ressource
    Online-Ressource
    Green Nanoparticles: The Future of Nanobiotechnology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Medicine Research. ; Biology Research. ; Zoology. ; Nanobiotechnology. ; Botany. ; Biomedical Research. ; Zoology. ; Nanobiotechnology. ; Plant Science.
    Beschreibung / Inhaltsverzeichnis: 1 Green nanotechnology: an overview -- 2 The Nano-Domain -- 3 Tools and Techniques Used in Nanobiotechnology -- 4 Green Synthesis of Nanoparticles -- 5 Biological Synthesis of Nanoparticles: Bacteria -- 6 Biological Synthesis of Nanoparticles: Fungi -- 7 Biological Synthesis of Nanoparticles: Algae -- 8 Biological Synthesis of Nanoparticles: Bryophytes -- 9 Biological synthesis of nanoparticles: Pteridophytes -- 10 Biological Synthesis of Nanoparticles: Gymnosperms -- 11 Biological Synthesis of Nanoparticles: Angiosperms- Monocotyledons -- 12 Biological Synthesis of Nanoparticles: Dicotyledons -- 13 Biological Synthesis of Nanoparticles: Animal Systems -- 14 Applications of Biosynthesized Nanoparticles -- 15 Toxicity Aspects of Biologically Synthesized Nanoparticles -- 16 Nanobiotechnology: Present Status and Future Prospects.
    Kurzfassung: This book discusses the fundamental concepts of the green synthesis of nanoparticles and presents the latest advances in this emerging field. Providing a comprehensive overview of developments related to nanoparticle synthesis using fungi, algae, bryophytes, pteridophytes, gymnosperms, monocotyledons, dicotyledonous (angiosperms) and animal systems, it also explores techniques for the characterization of these nanoparticles. Lastly, it reviews the applications and toxicity of biologically synthesized green nanoparticles. Given its scope, it is a valuable resource for students, researchers and policymakers working in the field of nanobiotechnology and nanoscience.
    Materialart: Online-Ressource
    Seiten: XIII, 352 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811671067
    URL: https://doi.org/10.1007/978-981-16-7106-7
    DOI: 10.1007/978-981-16-7106-7
    DDC: 610.72
    Sprache: Englisch
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