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  • Books  (5)
  • Biomedical Engineering and Bioengineering.  (4)
  • Biomedical Research.  (1)
  • Cham :Springer International Publishing :  (5)
  • 2020-2024  (5)
  • 2022  (5)
  • 660.6  (5)
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  • Books  (5)
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  • 2020-2024  (5)
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  • 1
    Keywords: Biotechnology. ; Medicine Research. ; Biology Research. ; Entrepreneurship. ; New business enterprises. ; Public health. ; Biotechnology. ; Biomedical Research. ; Entrepreneurship. ; Public Health.
    Description / Table of Contents: Part I. What Is Wrong with Health? What Should the Future of Health Be? -- INNOVATION DESIGN for the FUTURE of HEALTH -- Health Innovations from an Innovators’ Perspective -- From SICKCARE to HEALTHCARE to HEALTH -- Future Look on Health: Opportunities -- Navigating Towards a Future of “One Health” -- Part II. Exponential Medicine + Technologies + Mindset -- Exponential Technologies for an Exponential Medicine -- Exponential Medicine: Challenges of Human Spaceflight Bringing Innovations for Earth—A Case Study -- Healthy Longevity -- The Science of Health Longevity -- Space Healthtech: Innovation Base for Longevity -- Part III. Future Health Value Propositions -- Healthcare the Melting Pot of Technology, Humanity, and Confusion -- Democratize Health Delivery -- Health Innovation Process: Definitions and Short Methodology Introductions -- Prevention, Prediction, Personalization, and Participation as Key Components in Future Health -- Digital Health Business Models: Transformation Is on the Horizon -- Value Propositions for Future Health Developments: Digital, Portable, Connected, Experience-Enhancing, Supportive, Patient-Centric, and Affordable -- (Digital) Patient Journey and Empowerment: Digital Twin -- Part IV. Innovation Methodology Basics -- Stanford Biodesign as Base: Empathy and Patient Centricity as the Main Driver -- Purpose Launchpad Methodology: Introduction -- Design Thinking for Innovations in Healthcare -- VPC to BMC to Exponential Canvas: Canvas Interconnectivity for Exponential Scaling -- Innovation Methodology I3 EME: Awareness for Biomedical Engineers -- Part V. Ethics + Health Innovation -- Integrating Ethical Considerations into Innovation Design -- Part VI. Health Innovation Design -- Case Studies Used Throughout the Book: Innovation Categories Explained -- Why Is Healthcare Different with Respect to Innovation and Entrepreneurial Activities? -- Purpose Launchpad Health (PLH) Methodology Introduction -- Part VII. Purpose Launchpad Health -- Purpose Launchpad Health: Exploration and Evaluation Phases—Actual Case Studies -- Part VIII. Health Leadership, Skills and other Methodologies -- Soft Skills Needed for Problem Understanding and Innovation Generation -- Leadership in Healthcare: A Novel Approach. Healthcare Executives’ Traits, Styles, and Approaches -- Future Skills Framework in Healthcare -- Porter’s Five Forces Analysis: Quo Vadis Immunotherapy Industry -- Part IX. Health Entrepreneurship -- Global Health Markets and Their Different Needs -- Patient: Health Relation and Digital Health Entrepreneurship -- Health Start-Up: Create Impact and be Investment Ready Intra- and Entre-Preneurs -- Regulatory Issues for Health Innovations -- Innovation Think Tank Frameworks for Resolving “The Innovator’s Dilemma” in Healthcare -- A Primer on Patents and IP for Health Innovations -- Successfully Implementing Ambidexterity in the Medical Industry -- Reverse Innovation: Circumvent Digital Health Transformation Issues -- Part X. Health Innovation Education and Incubation -- Health Innovation Design: “CAMPing” for the Unmet Clinical Need -- Health Technology Innovation Generation (HTIG) Lecture and Project Classes at AGH University -- Health Innovation Design at a University: INKA INNOLAB at Otto-von-Guericke-University -- Clinical Innovation at Acibadem Biodesign Center -- Example of a Needs-Driven Innovation Training Program: The BioMedical Design Novo Nordisk Foundation Fellowship Program -- Addressing the Healthcare Needs with Innovation Think Tank Global Infrastructure and its Methodology -- The Power of a Collaborative Ecosystem: Introducing the Edison™ Accelerator -- HealthTec Networks and Clusters (Global): Innovation Clusters in Medtech in Europe -- Leadership-Compass: “Networking and Synapting Empowered by Health Captains” -- Part XI. Purpose Launchpad Health: Toolset Templates and Principles -- PLH Templates and Principles.
    Abstract: This book highlights the reasons for an urgently needed revision of the current global healthcare setup, discusses the needed mindset for a future of health, and provides a comprehensive development toolset for disruption (and for the needed incremental innovations towards disruption). Today’s biomedical and health innovation related research in universities encourages activities that lead to incremental innovations with a relatively low risk of failure. The healthcare industry on the other hand provides tools and devices for established healthcare providers to improve the diagnosis and therapy/ treatment of the patients’ health problems. The patient is not in the center of healthcare provision however, and prevention and prediction are not core goals. The current health setup needs to be challenged and disrupted. Disruptions are coming from technologies or processes that lead to a significant (〉10x) reduction in cost or price/ performance and that also come with new business models. The need for change, effects of exponential technologies, and the needed shift to prevention and to homecare for health democratization and patient empowerment will be discussed in detail in the first parts of the book. The subsequent sections address several innovation methods with a focus on a novel meta methodology named Purpose Launchpad Health. This is followed by a comprehensive discussion on health entrepreneurship activities and needs. The final section of the book addresses how to train students to become entrepreneurial health innovators, presenting successful curricula and examples of health incubation and accelerator setups. All of the innovation tools presented and used in this book are summarized in the final chapter to help the reader get started planning an entrepreneurial venture. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments. Chapters are concise and enriched with key messages, learning objectives and real innovation examples to bridge theory and practice. This book aims to serve as a teaching base for health innovation design and to prepare for health-related entrepreneurial ventures. Readers with medical, biomedical, biotechnology, and health economics backgrounds - and anyone who wants to become a future oriented health innovator or who believes in disruptive approaches - will find this book a useful resource and teaching tool for developing validated products/ services and processes for the future of health.
    Type of Medium: Online Resource
    Pages: XXXIV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031081910
    DDC: 660.6
    Language: English
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  • 2
    Keywords: Biotechnology. ; Neurology . ; Biomedical engineering. ; Biotechnology. ; Neurology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Section A Physiology -- An Overview On Sleep Medicine -- Covering The Gap Between Sleep And Cognition – Mechanisms and Clinical Examples -- Obstructive sleep apnoea: Focus on Pathophysiology -- Diagnosis of obstructive sleep apnea in patients with associated comorbidity -- Pediatric Obstructive Sleep Apnea: What’s in a Name? -- Treatment of Cheyne-Stokes respiration in heart failure with adaptive servo-ventilation: An integrative model -- Section B Diagnostic innovations -- Automated scoring of sleep and associated events -- Conventional machine-learning methods applied to the automatic diagnosis of sleep apnea -- Home Sleep Testing of Sleep Apnea -- ECG and heart rate variability in sleep-related breathing disorders -- Cardiopulmonary Coupling -- Pulse oximetry: the working principle, signal formation, and applications -- Oximetry indices in the management of sleep apnea: from overnight minimum saturation to the novel hypoxemia measures -- Airflow Analysis In The Context OF Sleep Apnea -- Deep-learning Model Based on Convolutional Neural Networks to Classify Apnea-hypopnea Events From The Oximetry Signal -- Tracheal sound analysis -- Obstructive Sleep Apnea with COVID-19 -- Section C Therapeutic innovations -- APAP, BPAP, CPAP and new modes of positive airway pressure therapy -- Adherence monitoring using telemonitoring techniques -- Innovations in The Treatment of Pediatric Obstructive Sleep Apnea -- Hypoglossal Nerve Stimulation Therapy -- Anna M. Mohammadieh -- Index.
    Abstract: The book focuses on biomedical innovations related to the diagnosis and treatment of sleep apnea. The latest diagnostic tools are described, including sleep laboratory equipment, wearables, and even smartphone apps. Innovative medical devices for treatment are also covered, such as CPAP, Auto-PAP, hypoglossal nerve stimulation, phrenic nerve stimulation, acoustic brain stimulation and electrical brain stimulation. This is an ideal book for biomedical engineers, pneumologists, neurologists, cardiologists, physiologists, ENT physicians, pediatrics, and epidemiologists who are interested in learning about the latest technologies in treating and diagnosing sleep apnea. Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XI, 389 p. 68 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031064135
    Series Statement: Advances in Experimental Medicine and Biology, 1384
    DDC: 660.6
    Language: English
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  • 3
    Keywords: Biotechnology. ; Radiology. ; Biomedical engineering. ; Neurosciences. ; Biotechnology. ; Radiology. ; Biomedical Engineering and Bioengineering. ; Neuroscience.
    Description / Table of Contents: Electromagnetic Properties and the Basis for CDI, MREIT and EPT -- Modeling for Electromagnetic Characterization, Prediction and Reconstruction -- Magnetic Resonance Imaging Basics -- Phantom Construction and Equipment Configurations for Characterizing Electrical Properties using MRI -- MR Current Density and MREIT Data Acquisition -- Magnetic Resonance Current Density Imaging (MR-CDI) -- Magnetic Resonance Electrical Impedance Tomography -- Index.
    Abstract: This book covers the latest developments in tissue electrical conductivity and current density imaging, increasingly popular as well as challenging applications of MRI. These applications are enabled by the acquisition of high-quality MR phase images. This book provides a practical description of the MRI physics needed to understand and acquire phase images in MRI and the key details required to reconstruct them into conductivity, current density or electric field distributions. Comprehensive details are provided about the electrical properties of biological tissues, computational modeling considerations, experimental methods, construction of non-biological and biological phantoms and MRI pulse sequences. An inclusive review of image reconstruction algorithms, and their potential applications is provided for applications directed at determining current density or electric fields, such as in transcranial DC or AC stimulation techniques; as well as electrical conductivity reconstructions that may be of use in quantitative MRI applications used to detect cancer or other pathologies. This is an excellent book for undergraduate and graduate students beginning to explore phase, current density, and conductivity imaging in MRI, and will also be of great use to researchers interested in the area of MR-based electrical property imaging.
    Type of Medium: Online Resource
    Pages: VII, 206 p. 101 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031038730
    Series Statement: Advances in Experimental Medicine and Biology, 1380
    DDC: 660.6
    Language: English
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  • 4
    Keywords: Biotechnology. ; Engineering design. ; Biomedical engineering. ; Biotechnology. ; Engineering Design. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: I. FUNDAMENTALS -- 1. The medical industry: Present situation, global health concerns and outlook -- 2. General considerations for engineering open-source medical devices.-3. Systematic assessment of needs and viability analyses.-II. DESIGN METHODS FOR OPEN-SOURCE MEDICAL DEVICES -- 4. Creativity promotion: Collaborative design environments & open-innovation.-5. Safety-guided design methods for open-source medical devices -- 6. Design and simulation of open-source medical devices -- III. MANUFACTURING METHODS FOR OPEN-SOURCE MEDICAL DEVICES -- 7. Prototyping of open-source medical devices -- 8. Manufacturing of personalized open-source medical devices -- 9. Mass-production of open-source medical devices -- IV. MAKING A REAL IMPACT WITH OPEN-SOURCE MEDICAL DEVICES -- 10. Open-source medical device approval and certification -- 11. Marketing open-source medical devices: Managing quality and supply chain -- 12. Issues linked to the long-term sustainability of open-source medical devices.
    Abstract: This book focuses on the challenges and potentials of open source and collaborative design approaches and strategies in the biomedical field. It provides a comprehensive set of good practices and methods for making these safe, innovative and certifiable biomedical devices reach patients and provide successful solutions to healthcare issues. The chapters are sequenced to follow the complete lifecycle of open source medical technologies. The information provided is eminently practical, as it is supported by real cases of study, in which collaboration among medical professionals, engineers and technicians, patients and patient associations, policy makers, regulatory bodies, and citizens has proven beneficial. The book is also supported by an online infrastructure, UBORA, through which open-source medical devices can be collaboratively developed and shared for the democratization of medical technology and for promoting accessible biomedical engineering education.
    Type of Medium: Online Resource
    Pages: VIII, 271 p. 86 illus., 78 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030793630
    DDC: 660.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Immunology. ; Biomedical engineering. ; Biotechnology. ; Immunology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: 1. The Musculoskeletal Burden – Where are we now? -- 2. Bacterial Adhesion, Virulence and Biofilm Formation -- 3. Prevention of Infection: Best Practice and Novel Strategies -- 4. Prosthetic Infection: Colonization and Diagnosis -- 5. Soft Tissue Infections -- 6. Incidence, Complications and Novel Treatment Strategies: Diabetic Ulcer of the Limb -- 7. Incidence, Complications and Novel Treatment Strategies: Osteomyelitis -- 8. Incidence, Complications and Novel Treatment Strategies: Joint Arthroplasty -- 9. Incidence, Complications and Novel Treatment Strategies: Massive Bone Tumour Surgery -- 10. Incidence, Complications and Novel Treatment Strategies: Pediatric Spinal Surgery & Management -- 11. War Wounds and Orthopaedic Trauma Devices.
    Abstract: This book gathers international knowledge and contemporary clinical and scientific evidence on infections associated with the musculoskeletal system at a time when we are confronted with significant challenges and uncertainty. A key focus of the book is enhancing and advancing future discovery in the detection, prevention and treatment of musculoskeletal infection. This is an ideal book for physicians, surgeons, research scientists, university students, as well as medical and allied health students.
    Type of Medium: Online Resource
    Pages: VII, 375 p. 41 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030832513
    DDC: 660.6
    Language: English
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