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  • Books  (18)
  • Regenerative Medicine and Tissue Engineering.  (12)
  • Computational and Systems Biology.
  • 660.6  (18)
  • 910.285
  • 1
    Online Resource
    Online Resource
    Essential Current Concepts in Stem Cell Biology (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Stem cells. ; Hematology. ; Regenerative medicine. ; Biotechnology. ; Stem Cell Biology. ; Hematology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Hematopoietic Stem Cells -- Mesenchymal Stem Cells -- Cord Blood Stem Cells -- Neural Stem Cells and Their Niche -- Skeletal Muscle Stem Cells -- Heart Muscle Tissue Engineering -- Induced Pluripotent Stem Cells -- Epigenetics of Somatic Cell Reprogramming -- Human Pluripotent Stem Cells and Neural Regeneration -- Dopaminergic Neuron-Related Stem Cells -- Liver Disease Modelling -- Organoids in Developmental Biology Research and Application -- Extracellular Vesicles -- Ethics in Stem Cell Applications.
    Abstract: This textbook describes the biology of different stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal cord blood, neural and muscle stem cells and also covers induced pluripotent stem cells and their applications. Further, it includes chapters on organoids, stem-cell based disease modelling, extracellular vesicles and one chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on lectures of the international master program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and participation of collaborating professors from Tongji University Shanghai, the book is a valuable source for students, postdocs and researchers, who would like to have introductory chapters on stem cell biology. It also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.
    Type of Medium: Online Resource
    Pages: XIV, 242 p. 37 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339234
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-33923-4
    DOI: 10.1007/978-3-030-33923-4
    DDC: 660.6
    Language: English
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  • 2
    Online Resource
    Online Resource
    Deep Learning in Medical Image Analysis : Challenges and Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Biomedical engineering. ; Radiology. ; Bioinformatics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Radiology. ; Computational and Systems Biology.
    Description / Table of Contents: Deep Learning in Medical Image Analysis -- Medical Image Synthesis via Deep Learning -- Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation -- Deep Learning Computer Aided Diagnosis for Breast Lesion in Digital Mammogram -- Decision support system for lung cancer using PET/CT and microscopic images -- Lesion Image Synthesis using DCGANs for Metastatic Liver Cancer Detection -- Retinopathy analysis based on deep convolution neural network -- Diagnosis of Glaucoma on retinal fundus images using deep learning: detection of nerve fiber layer defect and optic disc analysis -- Automatic segmentation of multiple organs on 3D CT images by using deep learning approaches -- Techniques and Applications in Skin OCT Analysis -- Deep Learning Technique for Musculoskeletal Analysis -- Index.
    Abstract: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
    Type of Medium: Online Resource
    Pages: VIII, 181 p. 131 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331283
    Series Statement: Advances in Experimental Medicine and Biology, 1213
    URL: https://doi.org/10.1007/978-3-030-33128-3
    DOI: 10.1007/978-3-030-33128-3
    DDC: 660.6
    Language: English
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  • 3
    Online Resource
    Online Resource
    Recent Advances in Biological Network Analysis : Comparative Network Analysis and Network Module Detection (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Bioinformatics. ; Medical genetics. ; Biotechnology. ; Computational and Systems Biology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Global Alignment of PPI Networks -- Chapter 2: Integrated Network-Based Computational Analysis for Drug Development -- Chapter 3: Effective Random Walk Models for Comparative Network Analysis -- Chapter 4: Computational Methods for Protein-Protein Interaction Network Alignment -- Chapter 5: Network Propagation for the Analysis of Multi_Omics Data -- Chapter 6: Motifs in Biological Networks -- Chapter 7: Bio Fabric Visualization of Network Alignments -- Chapter 8: Module Identification of Biological Networks via Graph Partition -- Chapter 9: Network Module Detection to Decipher the Heterogeneity of Cancer Mutations.
    Abstract: This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights. .
    Type of Medium: Online Resource
    Pages: XII, 217 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571733
    URL: https://doi.org/10.1007/978-3-030-57173-3
    DOI: 10.1007/978-3-030-57173-3
    DDC: 660.6
    Language: English
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  • 4
    Online Resource
    Online Resource
    Nanobiomaterial Engineering : Concepts and Their Applications in Biomedicine and Diagnostics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Nanotechnology. ; Regenerative medicine. ; Immunology. ; Biotechnology. ; Nanotechnology. ; Regenerative Medicine and Tissue Engineering. ; Immunology.
    Description / Table of Contents: Chapter 1. Nanomaterials, classifications, and properties -- Chapter 2. Engineering nanomaterials for bio-interfacing -- Chapter 3. Biomaterials and surface modification strategies -- Chapter 4. Nano materials as a nanotheronostic agent -- Chapter 5. Nanobiomaterials in biomedicine: Designing strategies and critical concepts -- Chapter 6. Phytofabricated nanodelivery systems: Engineering principles and applications -- Chapter 7. Nanobiosensors based diagnostics system: Transducers and surface materials -- Chapter 8. Nanobiomaterials and nanocomposites in clinical diagnostics -- Chapter 9. Tissue Engineering and Regenerative Medicines based on nanobiomaterials -- Chapter 10. Prospects and advantages of microfluidics utilizing various nanobiomaterials -- Chapter 11. Electrochemical nanoengineered sensors in infectious disease diagnosis -- Chapter 12. Multiplexing utilizing various nanobiomaterials -- Chapter 13. Future perspects of nanobiomaterials in human health care -- Chapter 14. Commercial aspects of nanobiomaterials: Short-coming and future aspects.
    Abstract: This book comprehensively documents the application of Nanobiomaterials in the field of bio-medicine and diagnostics technologies by involving classical concepts/examples. Nanobiotechnology is an emerging area which encompasses all the facets of research of nano and biomaterials with their interaction with biological systems. The book summarises design and development of various nanobiomaterials and their composites for diagnostics and therapeutic applications. It skilfully reviews the utilization of the nanomaterials alone or in combination with other bio-molecules as a contrast enhancer in in-vivo imaging, Nano-Theranostics, drug delivery, and sensing transducer matrix. It also discusses the current research on designing of the new Nanobiomaterials and their implementation in numerous fields including bio-medicine and diagnostics. Finally, it summarizes the future prospects and the commercial viability of Nanobiomaterials in the human health care.
    Type of Medium: Online Resource
    Pages: XII, 294 p. 108 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813298408
    URL: https://doi.org/10.1007/978-981-32-9840-8
    DOI: 10.1007/978-981-32-9840-8
    DDC: 660.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Bioimage Data Analysis Workflows (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Cytology. ; Bioinformatics. ; Biology Technique. ; Biotechnology. ; Cell Biology. ; Computational and Systems Biology. ; Biological Techniques.
    Description / Table of Contents: Workflows and Components of Bioimage Analysis -- Measurements of Intensity Dynamics at the Periphery of the Nucleus -- 3D Quantitative Colocalisation Analysis -- The NEMO Dots Assembly: Single-Particle Tracking and Analysis -- Introduction to MATLAB: Image Analysis & Brownian Motion -- Resolving the process of Clathrin Mediated Endocytosis Using Correlative Light & Electron Microscopy (CLEM).
    Abstract: This Open Access textbook provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platforms such as ImageJ, MatLab and Python. Besides gaining knowhow on algorithm usage, readers will learn how to create an analysis pipeline by scripting language; these skills are important in order to document reproducible image analysis workflows. The textbook is chiefly intended for advanced undergraduates in the life sciences and biomedicine without a theoretical background in data analysis, as well as for postdocs, staff scientists and faculty members who need to perform regular quantitative analyses of microscopy images.
    Type of Medium: Online Resource
    Pages: X, 170 p. 69 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030223861
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-22386-1
    DOI: 10.1007/978-3-030-22386-1
    DDC: 660.6
    Language: English
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  • 6
    Online Resource
    Online Resource
    Biomedical Visualisation : Volume 6 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Bioinformatics. ; Biotechnology. ; Computational and Systems Biology.
    Description / Table of Contents: Web-based 3D visualisation of biological and medical data -- Ultrasound-Guided Regional Anaesthesia: Visualising Nerve and Needle -- Scanning conditions in functional connectivity magnetic resonance imaging: how to standardise resting-state for optimal data acquisition and visualisation? -- Interactive VR Stroke Rehabilitation System Design -- Systematic review of Augmented and Virtual Reality in anatomical education -- Interdimensional travel: Visualisation of 3D-2D transitions in anatomy learning -- Anatomy Visualizations Using Stereopsis: Assessment and Implication of Stereoscopic Virtual Models in Anatomical Education -- Storyboarding in Medical Animation -- The hidden curriculum of imaging and utilisation of unregulated social media resources within clinical education -- Online distance learning in biomedical sciences: Community, belonging and presence. .
    Abstract: This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will be able to explore the utilisation of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences, with a focus in this volume related to anatomy, and clinically applied scenarios. The first eight chapters examine a variety of tools, techniques, methodologies and technologies which can be utilised to visualise and understand biological and medical data. This includes web-based 3D visualisation, ultrasound, virtual and augmented reality as well as functional connectivity magnetic resonance imaging, storyboarding and a variety of stereoscopic and 2D-3D transitions in learning. The final two chapters examine the pedagogy behind digital techniques and tools from social media to online distance learning techniques.
    Type of Medium: Online Resource
    Pages: XV, 181 p. 69 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030376390
    Series Statement: Advances in Experimental Medicine and Biology, 1235
    URL: https://doi.org/10.1007/978-3-030-37639-0
    DOI: 10.1007/978-3-030-37639-0
    DDC: 660.6
    Language: English
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  • 7
    Online Resource
    Online Resource
    Regenerative Medicine and Stem Cell Biology (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Reproductive health. ; Stem cells. ; Cancer. ; Biomedical engineering. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Reproductive Medicine. ; Stem Cell Biology. ; Cancer Biology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Basic Concepts of Stem Cells: The Facts and Hype in Stem Cells Research and Development -- Chapter 2. Embryonic and Pluripotent Stem Cells -- Chapter 3. Adult Stem Cells: Hematopoietic Stem Cells, and Control Of Hematopoiesis -- Chapter 4. Adult Stem Cells: Adult Stem Cells: Mesenchymal Stromal Cells, Endothelial Progenitor Cells and Pericytes -- Chapter 5. Cancer Stem Cells and the Development of Cancer -- Chapter 6. Stem Cell Applications In Metabolic Disorders: Diabetes Mellitus -- Chapter 7. Epigenetics in Stem Cell Biology -- Chapter 8. Practicum: Isolation of Bone Marrow and Adipose Tissue Mesenchyme Stromal Cells -- Chapter 9. Induced Pluripotent Stem Cells: Biology, History and in-vitro Generation -- Chapter 10. Tissue Engineering Modalities and Nanotechnology -- Chapter 11. Practicum: Scaffold engineering using the amniotic membrane -- Chapter 12. The Scientific Method, Ethical Consideration and Implications in Stem Cell Research.
    Abstract: This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.
    Type of Medium: Online Resource
    Pages: X, 374 p. 45 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030553593
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-55359-3
    DOI: 10.1007/978-3-030-55359-3
    DDC: 660.6
    Language: English
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  • 8
    Online Resource
    Online Resource
    Biomaterials in Tissue Engineering and Regenerative Medicine : From Basic Concepts to State of the Art Approaches (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Stem cells. ; Nanotechnology. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology. ; Nanotechnology.
    Description / Table of Contents: Module 1_Fundamentals of Biomaterials -- Module 2_Biomaterials in Tissue engineering -- Module 3_Applications of Biomaterials -- Module 4_Advances in Biomaterials.
    Abstract: This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.
    Type of Medium: Online Resource
    Pages: IX, 589 p. 88 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811600029
    URL: https://doi.org/10.1007/978-981-16-0002-9
    DOI: 10.1007/978-981-16-0002-9
    DDC: 660.6
    Language: English
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  • 9
    Online Resource
    Online Resource
    Decellularized Materials : Preparations and Biomedical Applications (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Biomaterials. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials.
    Description / Table of Contents: Chapter 1. Overview of decellularized materials for tissue repair and organ replacement -- Chapter 2. The decellularation of tissues -- Chapter 3. Different forms of decellularized tissues and their characteristics, applications in tissue repair as well as performance optimization -- Chapter 4. Applications of decellularized materials for tissue repair -- Chapter 5. The decellularation of organs derived from animals -- Chapter 6. Recellularization of Decellularized Whole Organ Scaffolds: Elements, Progress and Challenges -- Chapter 7. The applications of the recellularization organs in organ replacement at the stage of animal research -- Chapter 8. The challenges and development directions of decellularized materials.
    Abstract: This book will consist of 8 chapters, in which important issues regarding decellularized materials (DMs) will be discussed. This book will provide special knowledge of materials for the persons with biomedical background, and special biomedical knowledge for the persons with the background of materials, which will hopefully become a valuable informative read for the researchers and students of biomedical engineering major.
    Type of Medium: Online Resource
    Pages: X, 515 p. 158 illus., 135 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813369627
    URL: https://doi.org/10.1007/978-981-33-6962-7
    DOI: 10.1007/978-981-33-6962-7
    DDC: 660.6
    Language: English
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  • 10
    Online Resource
    Online Resource
    Bioinspired Biomaterials : Advances in Tissue Engineering and Regenerative Medicine (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Pharmaceutical chemistry. ; Neurosciences. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Pharmaceutics. ; Neuroscience. ; Chemical Bioengineering.
    Description / Table of Contents: Part I. Novel Bioinspired Biomaterials for Regenerative Medicine -- Chapter 1. Natural Sources and Applications of Demineralized Bone Matrix in the Field of Bone and Cartilage Tissue Engineering -- Chapter 2. Application of Gellan Gum-based Scaffold for Regenerative Medicine -- Chapter 3. Natural Fibrous Protein for Advanced Tissue Engineering Applications: Focusing on Silk Fibroin and Keratin -- Part II. Bioinspired 3D Bioprinting Hydrogel for Regenerative Medicine -- Chapter 4. Silk Fibroin Bioinks for Digital Light Processing (DLP) 3D Bioprinting -- Chapter 5. 3D-Bioprinting of Tissue Models with Customized Bioinks -- Chapter 6. Visible Light-curable Hydrogel Systems for Tissue Engineering and Drug Delivery -- Part III. Regulation of Stem Cell Fate by Bioinspired Biomaterials -- Chapter 7. Scaffolds for Cartilage Regeneration: To Use or Not to Use -- Chapter 8. Bio-application of Inorganic Nanomaterials in Tissue Engineering -- Chapter 9. Directional Cell Migration Guide for Improved Tissue Regeneration -- Part IV. Cutting-Edge Enabling Technology for Regenerative Medicine -- Chapter 10. Extracellular Vesicles: The Next Frontier in Regenerative Medicine and Drug Delivery -- Chapter 11. Application of Tissue Engineering and Regenerative Medicine in Maternal-fetal Medicine -- Chapter 12. Fundamentals and Current Strategies for Peripheral Nerve Repair and Regeneration -- Chapter 13. Protein-based Drug Delivery in Brain Tumor Therapy -- Chapter 14. Human Hair: Scaffold Materials for Regenerative Medicine.
    Abstract: This book is the first of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. Topics addressed in this volume, which is devoted to bioinspired biomaterials, range from novel biomaterials for regenerative medicine through to emerging enabling technologies with applications in, for example, drug delivery, maternal–fetal medicine, peripheral nerve repair and regeneration, and brain tumor therapy. New bioinspired hydrogels receive detailed attention in the book, and a further focus is the use of bioinspired biomaterials in the regulation of stem cell fate. Here the coverage includes the role of scaffolds in cartilage regeneration, the bioapplication of inorganic nanomaterials in tissue engineering, and guidance of cell migration to improve tissue regeneration. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials. .
    Type of Medium: Online Resource
    Pages: X, 229 p. 45 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811532580
    Series Statement: Advances in Experimental Medicine and Biology, 1249
    URL: https://doi.org/10.1007/978-981-15-3258-0
    DOI: 10.1007/978-981-15-3258-0
    DDC: 660.6
    Language: English
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  • 11
    Online Resource
    Online Resource
    Biomimicked Biomaterials : Advances in Tissue Engineering and Regenerative Medicine (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Pharmaceutical chemistry. ; Neurosciences. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Pharmaceutics. ; Neuroscience. ; Chemical Bioengineering.
    Description / Table of Contents: Part I. Novel Biomimicked Biomaterials for Regenerative Medicine -- Chapter 1. Bone Regeneration using Duck’s Feet Derived Collagen Scaffold as an Alternative Collagen Source -- Chapter 2. Decellularized Extracellular Matrices for Tissue Engineering and Regeneration -- Part II. Novel Biomimicked Hydrogel for Regenerative Medicine -- Chapter 3. Injectable in situ-forming Hydrogels for Protein and Peptide Delivery -- Chapter 4. Alginate Hydrogels as 3D Cell Encapsulation Matrices for Tissue Engineering and Regenerative Medicine -- Chapter 5. Design of Advanced Polymeric Hydrogels for Tissue Regenerative Medicine: Oxygen-controllable Hydrogel Materials -- Chapter 6. Enhancing Osteochondral Tissue Regeneration of Gellan Gum by Incorporating Gallus Gallus var Domesticus Derived Demineralized Bone Particle -- Part III. Control of Stem Cell Fate by Biomaterials for Regenerative Medicine -- Chapter 7. The Development of Extracellular Vesicles-Integrated Biomaterials for Bone Regeneration -- Chapter 8. In vivo Evaluation of the Biocompatibility of Biomaterial Device -- Chapter 9. Cell Response to Materials for Biomedical Engineering -- Chapter 10. Regulation of Stem Cell Functions by Micro-patterned Structures -- Part IV. Nano-Intelligent Biocomposites for Regenerative Medicine -- Chapter 11. Natural Polyphenols as Modulators of the Fibrillization of Islet Amyloid Polypeptide -- Chapter 12.Recent Advances of Biphasic Calcium Phosphate Bioceramics for Bone Tissue Regeneration -- Chapter 13. Surface-modifying Polymers for Blood-Contacting Polymeric Biomaterials.
    Abstract: This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.
    Type of Medium: Online Resource
    Pages: X, 198 p. 60 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811532627
    Series Statement: Advances in Experimental Medicine and Biology, 1250
    URL: https://doi.org/10.1007/978-981-15-3262-7
    DOI: 10.1007/978-981-15-3262-7
    DDC: 660.6
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  • 12
    Online Resource
    Online Resource
    Tissue Engineering : Principles, Protocols, and Practical Exercises (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Reference search, image & data analysis -- Organ structure & vascularization -- Extracellular matrix & adhesion molecules -- Isolating cells from tissue -- Functional assays & toxicity screening -- Culturing cells in 2D & 3D -- Imaging, staining & markers -- Stems cells & basics of immunology -- Natural & artificial Scaffolds -- Casting & 3D bioprinting -- Bioreactors -- Reporting results -- Index. .
    Abstract: Tissue engineering and regenerative medicine is a new, interdisciplinary branch of science that combines knowledge from numerous scientific fields including biology, biochemistry, physics, chemistry, applied engineering, and medicine. It aims to restore damaged parts of the human body by rebuilding them in vitro using individual building blocks of biological tissues such as cells and the extracellular matrix that surrounds them. The authors hope to spark students’ interest in this exciting new field of science as well as give them a basic knowledge of its terminology. This book is based on a hands-on practical course in tissue engineering conducted by the Fulbright US Scholar recipient, Dr. Narine Sarvazyan (George Washington University, Washington USA). It provides an overview of the core topics of the tissue engineering field, including stem cell differentiation, the role of extracellular matrix and attachment proteins, scaffolds, and culturing of engineered tissues. Each chapter is accompanied by hands-on demonstrations and self-check questions. The text is easily readable for students of all backgrounds and the described protocols can be conducted using common lab equipment. This textbook is also useful for developing undergraduate and graduate courses that teach basic methods and approaches in this promising and rapidly developing field. .
    Type of Medium: Online Resource
    Pages: XXIV, 154 p. 80 illus., 77 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030396985
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-39698-5
    DOI: 10.1007/978-3-030-39698-5
    DDC: 660.6
    Language: English
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  • 13
    Online Resource
    Online Resource
    Biomedical Visualisation : Volume 7 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Bioinformatics. ; Biotechnology. ; Computational and Systems Biology.
    Description / Table of Contents: Virtual Anatomy Museum – Facilitating Public Engagement Through An Interactive Application -- E-Learning And Embryology; Designing An Application To Improve 3D Comprehension Of Embryological Structures -- Animated Guide to Represent A Novel Means of Gut-brain Axis Communication -- Engaging with Children using Augmented Reality on Clothing to Prevent them from Smoking -- Enabling More Accessible MS Rehabilitation Training Using Virtual Reality -- The Use of Augmented Reality to Raise Awareness of the Differences between Osteoarthritis and Rheumatoid Arthritis -- Understanding the Brain and Exploring the Effects of Clinical Fatigue: From A Patient’s Perspective -- A Methodology for Visualising Growth and Development of the Human Temporal Bone -- Collect the Bones, Avoid the Cones: A Game-Based App for Public Engagement -- A Serious Game on Skull Anatomy for Dental Undergraduates. .
    Abstract: This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will be able to explore the utilisation of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences, with a focus in this volume related to anatomy, and clinically applied scenarios. All chapters in this volume feature collaborative and innovative postgraduate research projects from graduate students of the MSc Medical Visualisation and Human Anatomy. This pioneering, world-leading postgraduate taught degree program is a joint partnership degree between the School of Life Sciences within the College of Medical, Veterinary and Life Sciences in the University of Glasgow, and the School of Simulation and Visualisation, The Glasgow School of Art. These chapters truly showcase the amazing and diverse technological applications that have been carried out as part of their research projects.
    Type of Medium: Online Resource
    Pages: XVI, 237 p. 268 illus., 238 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030439613
    Series Statement: Advances in Experimental Medicine and Biology, 1262
    URL: https://doi.org/10.1007/978-3-030-43961-3
    DOI: 10.1007/978-3-030-43961-3
    DDC: 660.6
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  • 14
    Online Resource
    Online Resource
    Nanotechnology in Regenerative Medicine and Drug Delivery Therapy (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Biomaterials. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials.
    Description / Table of Contents: Magnetic responsive and nanostructured scaffolds for tissue regeneration -- Using nanomaterials to fabricate conductive materials for cardiac and neuron regeneration -- Nanotechnology in dental therapy and oral tissue regeneration -- Nanomaterials for immunomodulation and immnunotherapy: from mechanisms to prospective application -- Fabrication and Applications of Magnetic Nanoparticles-based Drug Delivery System: Challenges and Perspectives -- Drug co-delivery systems for uses in cancer therapies -- Molecular studies of amyloidal peptide assemblies and related applications in tumor diagnosis and therapeutics -- Self-Assembled DNA Nanostructures for Biomedical Applications -- Intermolecular Interactions and Self-Assembly of Peptide-based Nanomaterials Against Human Pathogenic Bacteria -- Development of realgar nanotherapeutics in cancer treatment -- Nanomaterials and Reactive oxygen species (ROS) -- Protein corona of nanoparticles and its application in drug delivery.
    Abstract: The book focuses on the application of nanotechnologies in scaffold-guided tissue regeneration and in drug delivery systems for use in immunotherapy and overcoming drug resistance in cancer treatment. It covers a variety of topics, including nanomaterials for immunomodulation and immnunotherapy; molecular studies on self-assembly for peptides and DNA and related applications in tumor diagnosis and therapeutics and against human pathogenic bacteria; magnetic and conductive scaffolds for guiding tissue regeneration; multiple functions of magnetic nanoparticles in drug delivery and regenerative medicine; and re-purposing of traditional medicine in nano-formulations. In addition, it discusses common effects of nanomaterials, including reactive oxygen species and protein corona. Providing valuable insights and the presenting the latest research advances, the book allows readers to gain a systematic understanding of the topic.
    Type of Medium: Online Resource
    Pages: XIV, 482 p. 109 illus., 95 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811553868
    URL: https://doi.org/10.1007/978-981-15-5386-8
    DOI: 10.1007/978-981-15-5386-8
    DDC: 660.6
    Language: English
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  • 15
    Online Resource
    Online Resource
    Models, Molecules and Mechanisms in Biogerontology : Cellular Processes, Metabolism and Diseases (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Geriatrics. ; Medicine Research. ; Biology Research. ; Medical genetics. ; Bioinformatics. ; Regenerative medicine. ; Biotechnology. ; Geriatrics. ; Biomedical Research. ; Medical Genetics. ; Computational and Systems Biology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: PART I ~ ALTERATIONS IN CELLULAR MECHANISMS DURING AGING -- Chapter 1 Protein Structure and Function in Aging and Age-related Diseases -- Chapter 2 DNA, DNA Replication and Aging -- Chapter 3 Transcription and Aging -- Chapter 4 Ribosomes, Translation and Aging -- Chapter 5 p53 and Aging -- Chapter 6 Paired Box (Pax) Transcription Factors and Aging -- Chapter 7 Telomeres, Telomerase and Aging -- Chapter 8 The Epigenome of Ageing -- Chapter 9 Attaining Epigenetic Rejuvenation: Challenges Ahead -- Chapter 10 Mitochondria as a Key Player in Aging -- Chapter 11 Aging, Free Radicals and Reactive Oxygen Species: An Evolving Concept -- Chapter 12 Stem Cells and Aging -- Chapter 13 Can Autophagy Stop the Clock: Unravelling the Mystery in Dictyostelium discoideum -- Chapter 14 Aging: Reading, Reasoning and Resolving Using Drosophila as a Model System -- Chapter 15 Nothobranchius furzeri as a New Model System for Aging Studies -- PART II ALTERATIONS IN METABOLISM DURING AGING AND DISEASES -- Chapter 16 Aging in Muscle -- Chapter 17 Metabolic Diseases and Aging -- Chapter 18 Interplay Between Nutrient Sensing Molecules During Aging and Longevity -- Chapter 19 Protein Aggregation, Related Pathologies and Aging -- Chapter 20 Biological Rhythms and Aging -- Chapter 21 The Biology of Ageing and Cancer – A Complex Association.
    Abstract: The book deals with basic cellular and molecular mechanisms associated with aging. It comprehensively describes the important genetic, epigenetic, biochemical and metabolic regulations during aging, as well as some important age-related diseases.The book is divided into four major sections for easy understanding. It takes the readers through the various aspects of aging in a story-like manner. Certain interventions for healthy aging such as dietary restriction, regular exercise and maintaining a balanced and peaceful life-style are also suggested by the experts. The book would be a companion for both beginners, as well as established researchers in the field. It would be useful for science education, research, clinical approach and policy making.
    Type of Medium: Online Resource
    Pages: XIII, 497 p. 77 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813290051
    URL: https://doi.org/10.1007/978-981-32-9005-1
    DOI: 10.1007/978-981-32-9005-1
    DDC: 660.6
    Language: English
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  • 16
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    Online Resource
    Machine Learning in Biological Sciences : Updates and Future Prospects (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Bioinformatics. ; Machine learning. ; Biotechnology. ; Computational and Systems Biology. ; Machine Learning. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. A Brief Overview Of Applications Of Machine Learning In Life Sciences -- Chapter 2. Introduction To Artificial Intelligence (Ai) Methods In Biology -- Chapter 3. Machine Learning Methods -- Chapter 4. Introduction To Machine Learning Models -- Chapter 5. Model Selection Formachine Learning -- Chapter 6. Multivariate Methods In Machine Learning In The Context Of Biological Data -- Chapter 7. Dimensionality Reduction Methods In Machine Learning -- Chapter 8. Hidden Markov Method -- Chapter 9. Neural Network And Deep Learning. Chapter 10. Ethics In Machine Learning And Artificial Intelligence -- Chapter 11. Machine Learning And Life Sciences -- Chapter 12. Machine Learning And Negleced Tropical Diseases- Chapter 13. Machine Learning In Cardiovascular Diseases -- Chapter 14. Machine Learning And Diabetes -- Chapter 15. Machine Learning And Epilepsy -- Chapter 16. The Microsoft, Google, Facebook, Pytorch And Applications In Biology -- Chapter 17. Applications And Software Of Machine Learning And Ai In Medical Knowledge In Health -- Chapter 18. Cloud Computing Infrastructure In Healthcare Industry -- Chapter 19. Amazon Web Services (Aws) And Microsoft Azure In The Domain Of Life Sciences -- Chapter 20. Toxicity: An Introduction -- Chapter 21. Machine Learning (Ml) And Toxicity Studies. Chapter 22. Applications Of Machine Learning In Study Of Cell Biology -- Chapter 23. Genomics And Machine Learning -- Chapter 24. Cell Fate Analysis And Machine Learning -- Chapter 25. Study Of Biomarker And Machine Learning -- Chapter 26. Animal Behaviour: An Introduction -- Chapter 27. Study Of Animal Behaviour And Machine Learning -- Chapter 28. Machine Learning And Precision Farming -- Chapter 29. Machine Learning In The Study Of Animal Health And Veterinary Sciences -- Chapter 30. Macinelearning And Animalresorviors -- Chapter 31. Challenging Problems In Plant Biology -- Chapter 32. Machine Learning And Plant Sciences. Chapter 33. Machine Learning In Understanding Of Plant Pathogen Interactions -- Chapter 34. Machine Learning In Plant Disease Research -- Chapter 35. Biorobots -- Chapter 36. The Challenges To Application Of Machine Learning In Biological Sciences -- Chapter 37. The Future Of Machine Learning.
    Abstract: This book gives an overview of applications of Machine Learning (ML) in diverse fields of biological sciences, including healthcare, animal sciences, agriculture, and plant sciences. Machine learning has major applications in process modelling, computer vision, signal processing, speech recognition, and language understanding and processing and life, and health sciences. It is increasingly used in understanding DNA patterns and in precision medicine. This book is divided into eight major sections, each containing chapters that describe the application of ML in a certain field. The book begins by giving an introduction to ML and the various ML methods. It then covers interesting and timely aspects such as applications in genetics, cell biology, the study of plant-pathogen interactions, and animal behavior. The book discusses computational methods for toxicity prediction of environmental chemicals and drugs, which forms a major domain of research in the field of biology. It is of relevance to post-graduate students and researchers interested in exploring the interdisciplinary areas of use of machine learning and deep learning in life sciences.
    Type of Medium: Online Resource
    Pages: XXI, 336 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811688812
    URL: https://doi.org/10.1007/978-981-16-8881-2
    DOI: 10.1007/978-981-16-8881-2
    DDC: 660.6
    Language: English
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  • 17
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    Online Resource
    Biomedical Product Development: Bench to Bedside (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Medical sciences. ; Biomedical engineering. ; Pharmaceutical chemistry. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Health Sciences. ; Biomedical Engineering and Bioengineering. ; Pharmaceutics.
    Description / Table of Contents: 1. An Introduction to Biomedical Product Development -- 2. Basic Essentials and Applications of Quality Management System (QMS) in Biomedical Sciences -- 3. Principles of Good Laboratory Practice (GLP) -- 4. Design of Experimental Studies in Biomedical Sciences -- 5. Preclinical Studies for Development of Biomedical Products -- 6. Principles of Good Manufacturing Practice (GMP) -- 7.The importance of Cleanroom facility in manufacturing of biomedical products -- 8. Safety concerns and requirement of cell based products for clinical application -- 9. Standards and regulatory frameworks (for cell and tissue based products) -- 10. Principles of Good clinical Practice (GCP) -- 11. Design, performance and monitoring of clinical trials -- 12. Good Clinical Practice: Guidelines and Requirement -- 13. Ethical Considerations of Biomedical Products Development.
    Abstract: This textbook covers all the steps in manufacturing a biomedical product from bench to bedside. It specifically focuses on quality assurance and management and explains the different good practice principles in the various phases of product development as well as how to fulfill them: Good laboratory practice, good manufacturing practice and good clinical practice. It provides readers with the know-how to design biomedical experiments to ensure quality and integrity, to plan and conduct standard preclinical studies and to assure the quality of the final manufactured biomedical products. Importantly, it also addresses ethical concerns and considerations. The book discusses the guidelines and ethical considerations for preclinical and clinical studies, to allow readers to identify safety concerns regarding biomedical products and to improve pre-clinical studies for the development of better products. This textbook is a valuable guide for biomedical students (B.Sc., M.S., and Ph.D. students) in the field of molecular medicine, medical biotechnology, stem cell research and related areas, as well as for professionals such as quality control staff, tissue bankers, policy-makers and health professionals.
    Type of Medium: Online Resource
    Pages: XIV, 157 p. 16 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030356262
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-35626-2
    DOI: 10.1007/978-3-030-35626-2
    DDC: 660.6
    Language: English
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  • 18
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    Online Resource
    Basic Concepts on 3D Cell Culture (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Cytology Technique. ; Biomedical engineering. ; Regenerative medicine. ; Biotechnology. ; Cytological Techniques. ; Biomedical Engineering and Bioengineering. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Chapter 1. Introduction to 3D cell culture -- Chapter 2. Lab equipment for 3D cell culture -- Chapter 3. A view from the cellular perspective -- Chapter 4. Biological, natural and synthetic 3D matrices -- Chapter 5. Hydrogels for 3D cell culture -- Chapter 6. Vascularization in 3D cell culture -- Chapter 7. Application of scaffold-free 3D models -- Chapter 8. 10. Microfluidic Systems and Organ (Human) on a Chip -- Chapter 9. 3D-Bioprinting -- Chapter 10. Non-destructive and label-free monitoring of 3D cell constructs.
    Abstract: This textbook shall introduce the students to 3D cell culture approaches and applications. An overview on existing techniques and equipment is provided and insight into various aspects and challenges that researchers need to consider and face during culture of 3D cells is given. The reader will learn the importance of physiological cell, tissue and organ models and gains important knowledge on 3 D analytics. This textbook deepens selected aspects of the textbook “Cell Culture Technology”, which also is published in this series, while offering extended insight into 3D cell culture. The concept of the textbook encompasses various lectures ranging from basics in cell cultivation, tissue engineering, biomaterials and biocompatibility, in vitro test systems and regenerative medicine. The textbook addresses Master- and PhD students interested and/or working in the field of modern cell culture applications and will support the understanding of the essential strategies in 3D cell culture and waken awareness for the potentials and challenges of this application.
    Type of Medium: Online Resource
    Pages: XV, 252 p. 88 illus., 83 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030667498
    Series Statement: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-030-66749-8
    DOI: 10.1007/978-3-030-66749-8
    DDC: 660.6
    Language: English
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