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  • Bioinformatics.
  • Geotechnical Engineering and Applied Earth Sciences.
  • Geotechnical engineering.
  • Nanotechnology.
  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Surfaces (Physics). ; System theory. ; Zoology. ; Botany. ; Biology Technique. ; Computational and Systems Biology. ; Surface and Interface and Thin Film. ; Complex Systems. ; Zoology. ; Plant Science. ; Biological Techniques.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Various methods of pattern formation -- Chapter 3. Clusterization of biological structures with high aspect ratio -- Chapter 4. Contact between biological attachment devices and rough -- Chapter 5. Anisotropic friction in biological systems -- Chapter 6. Mechanical interlocking of biological fasteners -- Chapter 7. Biomechanics at the microscale -- Chapter 8. Nanoscale pattern formation in biological surfaces -- Chapter 9. Ecology and evolution.
    Abstract: Basic laws of nature are rather simple, but observed biological structures and their dynamic behaviors are unbelievably complicated. This book is devoted to a study of this “strange” relationship by applying mathematical modeling to various structures and phenomena in biology, such as surface patterns, bioadhesion, locomotion, predator-prey behavior, seed dispersal, etc. and revealing a kind of self-organization in these phenomena. In spite of diversity of biological systems considered, two main questions are (1) what does self-organization in biology mean mathematically and (2) how one can apply this knowledge to generate new knowledge about behavior of particular biological system? We believe that this kind of “biomimetics” in computer will lead to better understanding of biological phenomena and possibly towards development of technical implications based on our modeling.
    Type of Medium: Online Resource
    Pages: XVIII, 317 p. 151 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030415280
    Series Statement: Biologically-Inspired Systems, 16
    DDC: 570.285
    Language: English
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  • 2
    Keywords: Paleoecology. ; Paleontology . ; Bioinformatics. ; Archaeology. ; Earth sciences. ; Paleoecology. ; Paleontology. ; Computational and Systems Biology. ; Archaeology. ; Earth Sciences.
    Description / Table of Contents: Chapter 1-Introduction -- Chapter 2-Historical perspective -- Chapter 3-Geology and stratigraphy -- Chapter 4-Indian late cretaceous dinosaur nesting sites -- Chapter 5-Discussion. Chapter -- 6-Summary and conclusions.
    Abstract: This book documents analyses of the Late Cretaceous dinosaur nesting sites of the Lameta Formation at Jabalpur, Districts Dhar and Jhabua, Madhya Pradesh; Districts Kheda and Panchmahal (Gujarat); and the Pisdura, Dongargaon and Pavna sectors in the Chandrapur Districts of Maharashtra, which are exposed in India along an east-west and central axis. In this work, special emphasis has been given to the dinosaur nesting sites of the east-central Narbada River region, including its regional geology. The work was undertaken to provide detailed information concerning dinosaur eggs, eggshell fragments, nests and clutches found in the Lameta Formation of peninsular India. Prior to the present work there had been no detailed review of systematic work on the taxonomy, and of micro- and ultrastructural studies of dinosaur eggs and eggshells from the Lameta Formation. The study documents the field and laboratory investigations that facilitated the reconstruction of the morphotaxonomy, models for the burial pattern of eggs and eggshells, taphonomic implications,and the palaeoenvironmental context and palaeoecological conditions during the Late Cretaceous at the time of the extrusion of the Deccan traps, which may have been partly responsible for the extinction of the dinosaurs. The need to follow a parataxonomic classification for Indian dinosaur eggs and eggshell types is very apparent, and this book addresses this aspect in some detail. The emphasis on the application of parataxonomic schemes is based on the description of new oospecies and their comparison with previously known forms. The present work has led to the recovery of numerous nests, many collapsed eggs and hundreds of dinosaur eggshell fragments from the localities situated near the east, west and central Narbada River regions. It will be of interest to academics and professional palaeontologists, and all students of dinosaurs.
    Type of Medium: Online Resource
    Pages: XX, 280 p. 92 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030564544
    Series Statement: Topics in Geobiology ; 51
    DDC: 560.45
    Language: English
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  • 3
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biomaterials. ; Nucleic acids. ; Bioinformatics. ; Biology Technique. ; Nucleic Acid. ; Computational and Systems Biology. ; Biological Techniques.
    Description / Table of Contents: Chapter 1. Strategies in Life sciences -- Chapter 2. Management and Manufacturing process of biologics -- Chapter 3. Downstream processes -- Chapter 4. Bioprinting -- Chapter 5. Biopharmaceuticals: New Frontier.
    Abstract: Tailoring of biomolecules using protein engineering technology, and host cells culture techniques are among the most sophisticated and elegant achievements of modern applied life sciences in which the basic fundamentals biotechnology are applicable for the development and manufacturing of biologics and other related bio-molecules for a hurdle free life with good health. A majority of biologics derived from genetically modified host cells in the current market are bio-formulation such as antibodies, nucleic acid products and vaccines. Such bio-formulations are developed mainly in two steps i.e. upstream process and downstream process. The first volume of this series begins with the latest information on how the classical stepwise host cells culture (mammals, animals, plants, and bacteria) methodology has been changed to fully continuous or partially continuous host cells culture process in order to economise the biopharmaceutical products manufacturing process. In addition this volume narrates a brief history on conceptual development of new thoughts in designing biotechnology industries for commercial production of variety of therapeutic proteins with structural modification on the basis of clinical requirements. The readers will feel exited by going through the latest discovery and development in applied life sciences for designing innovative biomolecules for health care with utmost safe. The most interesting part of this volume is newly developed concept on bioprinting. It explains how to design and fabricate animate objects by fusing or depositing material of interest in the form of powders, solid dusts, metal, liquid or even living cells or tissues by layers to produce 3D objectives. The first volume ends with the latest information on the current trend in biologics market, market dynamic, drives, and opportunities with challenges.
    Type of Medium: Online Resource
    Pages: XV, 189 p. 84 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811575907
    Series Statement: New Paradigms of Living Systems, 1
    DDC: 620.19
    Language: English
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  • 4
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Bioinformatics. ; Immunology. ; Cancer Biology. ; Computational and Systems Biology. ; Immunology.
    Description / Table of Contents: 1. Introduction: Introduction of lipids, lipid metabolism and tumor immunity -- 2. ipid metabolism and lipidomics -- 3. Applications of lipidomics in tumour immunity.-4. Overview: Lipid metabolism in tumour microenvironment -- 5. Lipid metabolism in cancer cells -- 6. Lipid metabolism in tumour-associated NK -- 7. Lipid metabolism in tumour-associated macrophages -- 8. Lipid metabolism in tumour-associated MDSCs -- 9. Lipid metabolism in tumour-associated fibroblasts -- 10. Lipid metabolism in tumour-associated B cells -- 11. Lipid metabolism in tumour-infiltrating T cells -- 12. Lipid metabolism and angiogenesis -- 13. Lipid metabolism and tumor antigen-presenting -- 14. Lipid metabolism and immune checkpoints.
    Abstract: This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery. .
    Type of Medium: Online Resource
    Pages: XI, 211 p. 24 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813367852
    Series Statement: Advances in Experimental Medicine and Biology, 1316
    DDC: 571.978
    Language: English
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  • 5
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Human physiology. ; Radiology. ; Diseases. ; Bioinformatics. ; Immunology. ; Human Physiology. ; Radiology. ; Diseases. ; Computational and Systems Biology. ; Immunology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. The Economics of Obesity-A Public Policy Perspective -- Chapter 3. Obesity and skin problems -- Chapter 4. Obesity and endometriosis -- Chapter 5. Hypogonadism -- Chapter 6. Effect of obesity in cardiovascular system -- Chapter 7. Impact of obesity on vaccination -- Chapter 8. Obesity-linked diseases (Comorbidities) -- Chapter 9. Imaging as a tool for measuring body fat -- Chapter 10. Extrapolation from clinical trial to practice: current pharmacotherapy on obesity -- Chapter 11. Nanotechnology in the context of obesity -- Chapter 12. Computational approach in drug development for obesity.
    Abstract: This book summarizes the effects of obesity on health and its correlation with a wide range of debilitating and life-threatening conditions in humans. It discusses the possible pathological mechanisms that are involved in the development of obesity and highlights obesity-associated molecular mechanisms that contribute to reproductive dysfunctions in men and women. The book provides mechanistic insights on the role of obesity in cardiovascular and respiratory disorders, and examines the role of the complementary molecular mechanism of the gut microbiota in the development of obesity. It also reviews the interaction between the metabolic system and immune cells in the pathogenesis of obesity-associated diseases. Lastly, it assesses the latest advances in nanomedicine as an emerging strategy for the treatment of obesity.
    Type of Medium: Online Resource
    Pages: XVI, 181 p. 13 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813364080
    DDC: 612
    Language: English
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  • 6
    Keywords: Neurosciences. ; Biomedical engineering. ; Nanotechnology. ; Biophysics. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Nanoengineering. ; Bioanalysis and Bioimaging. ; Biological Imaging.
    Description / Table of Contents: Part 1 -- Optically-Pumped Magnetometers Compatible with Large Transient Magnetic Fields -- Small animal biomagnetism applications -- Supine OPM-MEG in Multi-layer Cylindrical Shield -- Ambulatory MEG Arrays -- Part 2 -- "Tri-axial helium-4 optically-pumped -- magnetometers for MEG" -- Person-Sized Magnetoencephalography Systems with Optically Pumped Magnetometers -- On-scalp MEG with High-Tc SQUIDs -- "Fiber Coupled OPM in Purely Coil -- Shielded Environment" -- SERF-OPM usability for MEG in two-layer shielded rooms -- Turning OPM-MEG into a Wearable Technology -- Part 3 -- OPM Gradiometer for Magnetorelaxometry -- Unshielded High Bandwidth Magnetorelaxometry of Magnetic Nanoparticles with Optically Pumped Magnetometers -- Adult Magnetocardiography: Principles and Clinical Practice -- Fetal Magnetocardiography with OPMs -- Emerging MR sensors for biomagnetic measurements -- Index.
    Abstract: This contributed volume reviews the latest advances in all the new technologies currently developed for MagnetoEncephaloGraphy (MEG) recordings, as well as sensor technologies and integrated sensor arrays for on-scalp MEG. The book gives an account of the first MEG imaging studies and explores the new field of feasible, experimental paradigms of on-scalp MEG. This is an ideal book for engineers, researchers, and students in the neurosciences interested in MEG imaging. .
    Type of Medium: Online Resource
    Pages: IX, 315 p. 104 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031053634
    DDC: 612.8
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Post-translational modification. ; Bioinformatics. ; Molecular biology. ; Nervous system Diseases. ; Post-translational Modifications. ; Computational and Systems Biology. ; Molecular Biology. ; Neurological Disorders.
    Description / Table of Contents: Protein extraction and sample preparation methods for shotgun proteomics with central nervous system cells and brain tissue -- Phosphopeptide enrichment techniques: a pivotal step for phosphoproteomic studies -- Post-Translational Modifications during Brain Development -- Aberrant protein glycosylation in brain cancers, with emphasis on glioblastoma -- Post-Translational Modification in Muscular Dystrophies -- Post-translational Modifications in Parkinson’s Disease -- Histone Modifications in Neurological Disorders -- Mitochondrial dysregulation and the influence in neurodegenerative diseases -- PTMs: A missing piece for schizophrenia studies -- Post-Translational Modifications in Brain Diseases: A Future for Biomarkers -- Index.
    Abstract: This new volume, a part of the Proteomics, Metabolomics, Interactomics and Systems Biology series, will explain how proteomic studies of post-translational modifications (PTMs) can be applied to neurodegenerative diseases and relevant studies. The goal of the book is to increase awareness among researchers about how PTMs may be helpful in understanding mechanisms in various neurodegenerative diseases through proteomic studies. This book will serve as a tool for those who want to begin work in the proteomics field and explore how to implement PTMs studies into their work. Chapter authors will describe different PTMs enrichment methods developed by experts in the field so that researchers may learn to apply these methods and techniques to new studies. Divided into three sections, chapters will cover sample preparation, data quality, enrichment techniques, guidelines on how to analyze PTMs, and explain the role of PTMs and different brain diseases. Among those topics includes will be brain cancer, SLA disease, Parkinsons disease, muscular dystrophies, and schizophrenia. This volume will be useful for researchers and students studying brain and neurodegenerative diseases who are interested in delving into work with proteomic studies and PTMs. .
    Type of Medium: Online Resource
    Pages: VIII, 146 p. 13 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031054600
    Series Statement: Proteomics, Metabolomics, Interactomics and Systems Biology, 1382
    DDC: 572.645
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agriculture. ; Nanotechnology. ; Botanical chemistry. ; Plant physiology. ; Plant biotechnology. ; Plants Development. ; Agriculture. ; Nanotechnology. ; Plant Biochemistry. ; Plant Physiology. ; Plant Biotechnology. ; Plant Development.
    Description / Table of Contents: 1. Nanotechnology: A breakthrough in Agronomy -- 2. Nanotechnology and Plant Tissue Culture -- 3. Nanotechnology and abiotic stresses -- 4. Myconanoparticles in agriculture -- 5. Nanotechnology in pest management -- 6. DNA nanobiotechnology and plant breeding -- 7. Nanotechnology and Plant Disease Diagnosis and Management -- 8. Nanofertilizers -- 9. Nanotechnology and waste water treatment -- 10. Applications of nano-biosensors in agriculture -- 11. Nanomaterials and agriwaste -- 12. Prospects and constraints.
    Abstract: In this age of population explosion and depleting natural resources, this book offers new techniques to produce more from agricultural crops at a lower cost. The field of agronomy addresses this issue and interacts with the fields of agriculture, botany, and economics. Nanotechnology and nanoparticles play a role in agronomy. This book joins techniques from both fields into once comprehensive volume. Students of agriculture, physics, nanotechnology, and plant sciences will benefit equally from this work.
    Type of Medium: Online Resource
    Pages: IX, 221 p. 40 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030412753
    DDC: 630
    Language: English
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  • 9
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Food science. ; Nutrition   . ; Bioinformatics. ; Biotechnology. ; Food Science. ; Nutrition. ; Computational and Systems Biology. ; Biotechnology.
    Description / Table of Contents: Soybean (Glycine max) -- Rapeseed/Canola (Brassica napus) -- Cottonseed (Gossypium hirsutum),- Ground nut (Arachis hypogaea) -- Sunflower (Helianthus annuus) seed -- Palm /Palm kernel (Elaeis guineensis) -- Coconut (Cocos nucifera),- Mustard (Brassica nigra) seed,- Olive (Olea europaea),- Flaxseed (Linum usitatissimum), - Chia seed (Salvia hispanica),- Sesame (Sesamum indicum) seed -- Nigella (Nigella sativa) seed,- Borage (Borago officinalis) seed,- Hempseed (Cannabis sativa),- Rice (Oryza sativa) bran,- Safflower (Carthamus tinctorius) -- Camelina (Camelina sativa) seed,- Pumpkin (Cucurbita pepo) seed,- Cumin (Cuminum cyminum) seed.
    Abstract: Oilseeds offer a plethora of opportunities for the food and feed industry, thanks to their high oil and protein content . Their phytonutrients and functional components have attracted the interest of researchers, leading to the development of functional foods. This book gathers the latest scientific information on the nutrients, phytonutrients and health benefits as well as the adverse effects of consuming various conventional and non-conventional oilseeds. In addition, each chapter includes a section comprehensively explaining the use of oilseeds in functional bakery, dairy, and other food products. Given its scope, the book is a valuable resource for students, researchers, nutritionists, food scientists and technologists, and for anyone involved in product development based on oilseed and its components.
    Type of Medium: Online Resource
    Pages: IX, 517 p. 42 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811541940
    DDC: 641.3
    Language: English
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  • 10
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Nanotechnology. ; Cancer. ; Stem cells. ; Diseases. ; Biotechnology. ; Nanotechnology. ; Cancer Biology. ; Stem Cell Biology. ; Diseases.
    Description / Table of Contents: Chapter 1.Current Advances in Nanotechnology and Medicine -- Chapter 2. Least Explored Small Wonders: Nano-biotechnology -- Chapter 3. Modern Approaches in Nanomedicine for neuroAIDS and CNS drug delivery -- Chapter 4. Nanobiotechnology: Paving the way to personalized medicine -- Chapter 5. Nanomedicine in cancer stem cell therapy -- Chapter 6. Nanobiosensor: Current Trends and Applications -- Chapter 7. Transition Metal Oxide Nanoparticles: A New Horizon in Cancer Treatment -- Chapter 8. Nanomedicine meets microRNA expression and function in prostate cancer -- Chapter 9. Biomedical applications of Viral Nanoparticles in vaccine therapy -- Chapter 10. HIV: Biology to Nanomedicine -- Chapter 11. Current Advances in Phage Inspired Nanocarriers Based Therapy -- Chapter 12. Nanophytotherapeutic potential of Essential Oils against Candida infections -- Chapter 13. Molecular tests for the Diagnosis of Tuberculosis: Nanodiagnostics Approaches -- Chapter 14. Molecular Mechanisms of drug resistance in Mycobacterium tuberculosis: Role of nanoparticles against Multi-Drug Resistant tuberculosis (MDR-TB) -- Chapter 15. Nano-Mass spectrometry (nano-MS) based lipidomics -- Chapter 16. Techniques to understand Mycobacterial Lipids and use of Lipid Based Nanoformulations for Tuberculosis Management -- Chapter 17. Recent trends and challenges in Patches for cardiac tissue reengineering: role of Nanomaterials -- Chapter 18. Cyclic dinucleotides: Big roles of small molecules and its role in nanotechnology and medicine -- Chapter 19. Antibodies: Biology to Therapeutics and its role in nanomedicine -- Chapter 20. Nanotoxicology in Medicine -- Chapter 21. Antibody-targeted nanoparticles for cancer treatment -- Chapter 22. Nanoparticle mediated combined photothermal and photodynamic therapy -- Chapter 23. Nanotechnology based devices and its applications in medicine- Chapter 24. Opportunities in clinical translation and commercialization of nanomedicine. .
    Abstract: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology. .
    Type of Medium: Online Resource
    Pages: XX, 517 p. 90 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813298989
    DDC: 660.6
    Language: English
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  • 11
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cytology. ; Bioinformatics. ; Imaging systems in biology. ; Cell Biology. ; Computational and Systems Biology. ; Biological Imaging.
    Description / Table of Contents: Introduction -- Batch Processing Methods in ImageJ -- Python: Data Handling, Analysis and Plotting -- Building a Bioimage Analysis Workflow Using Deep Learning -- GPU-Accelerating ImageJ Macro Image Processing Workflows Using CLIJ -- How to Do the Deconstruction of Bioimage Analysis Workflows: A Case Study with SurfCut -- i.2.i. with the (Fruit) Fly: Quantifying Position Effect Variegation in Drosophila Melanogaster -- A MATLAB Pipeline for Spatiotemporal Quantification of Monolayer Cell Migration.
    Abstract: This open access textbook aims at providing detailed explanations on how to design and construct image analysis workflows to successfully conduct bioimage analysis. Addressing the main challenges in image data analysis, where acquisition by powerful imaging devices results in very large amounts of collected image data, the book discusses techniques relying on batch and GPU programming, as well as on powerful deep learning-based algorithms. In addition, downstream data processing techniques are introduced, such as Python libraries for data organization, plotting, and visualizations. Finally, by studying the way individual unique ideas are implemented in the workflows, readers are carefully guided through how the parameters driving biological systems are revealed by analyzing image data. These studies include segmentation of plant tissue epidermis, analysis of the spatial pattern of the eye development in fruit flies, and the analysis of collective cell migration dynamics. The presented content extends the Bioimage Data Analysis Workflows textbook (Miura, Sladoje, 2020), published in this same series, with new contributions and advanced material, while preserving the well-appreciated pedagogical approach adopted and promoted during the training schools for bioimage analysis organized within NEUBIAS – the Network of European Bioimage Analysts. This textbook is intended for advanced students in various fields of the life sciences and biomedicine, as well as staff scientists and faculty members who conduct regular quantitative analyses of microscopy images.
    Type of Medium: Online Resource
    Pages: X, 212 p. 265 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030763947
    Series Statement: Learning Materials in Biosciences,
    DDC: 571.6
    Language: English
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  • 12
    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Enzymology. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Enzymology. ; Nanotechnology.
    Description / Table of Contents: Immobilization: Then and Now -- Cell immobilization strategies for tissue engineering: Recent trends and future perspectives -- Strategies and advancement in growth factor immobilizable ECM for tissue engineering -- Prospects Of Cell Immobilization In Cancer Research And Immunotherapy -- Nano systems for repairing retinal degeneration -- Systemic drug delivery to the posterior segment of the eye: Overcoming blood-retinal barrier through smart drug design and nanotechnology -- The effects of irradiation with cold atmospheric-pressure plasma on cellular function -- Immobilization of biomolecules on plasma functionalized surfaces for biomedical applications -- A wide portray of Upconversion-nanoparticles: surface modification for bio-applications -- Advances in Amphiphilic Assemblies and its Immobilization in Room Temperature Supercooled Matrices. .
    Abstract: This book delves into the field of immobilizing biologically active and non-active molecules. It discusses the designing strategy of immobilization and the current state-of-the-art applications for advancing biomedical, agricultural, environmental and industrial practices. It focuses on aspects ranging from fundamental principles to current technological advances at multi-scale levels (macro, micro, and nano) which are suitable for cell, enzyme, and nano-catalyst based applications. Written by experts from across the globe, the contents deal with illustrated examples of molecular and cellular interactions with materials/scaffolds and discussions on factors that can affect the functionality and yield of the process. With its discussions on material science, design of delivery vehicles, separation science, additive manufacturing, agriculture and environmental science, this book will be a useful reference for researchers across multiple disciplines.
    Type of Medium: Online Resource
    Pages: X, 666 p. 143 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811579981
    Series Statement: Gels Horizons: From Science to Smart Materials,
    DDC: 660.6
    Language: English
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  • 13
    Keywords: Phylogeny. ; Biology Technique. ; Gene expression. ; Bioinformatics. ; Phylogenetics. ; Gene Expression Analysis. ; Bioinformatics.
    Description / Table of Contents: Introduction to phylogenetic trees -- A divergence time story: the rise and fall of the molecular clock -- Estimating phylogenetic trees -- Estimating divergence times -- Estimating common ancestors -- Testing theories of molecular evolution -- Recommendations for further reading -- Appendix A: Intermittent point processes -- Appendix B: Poisson processes with Lévy-stable substitution rates.
    Abstract: This book serves as a brief introduction to phylogenetic trees and molecular evolution for biologists and biology students. It does so by presenting the main concepts in a variety of ways: first visually, then in a history, next in a dice game, and finally in simple equations. The content is primarily designed to introduce upper-level undergraduate and graduate students of biology to phylogenetic tree reconstruction and the underlying models of molecular evolution. A unique feature also of interest to experienced researchers is the emphasis on simple ways to quantify the uncertainty in the results more fully than is possible with standard methods.
    Type of Medium: Online Resource
    Pages: XIII, 106 p. 21 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031119583
    Series Statement: SpringerBriefs in Systems Biology,
    DDC: 576.88
    Language: English
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  • 14
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Diseases. ; Immunology. ; Bioinformatics. ; Cancer Biology. ; Diseases. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Obesity induced chronic low-level inflammation and cancers -- Chapter 2. Adipose tissue produced estrogen as risk factor for cancers -- Chapter 3. Insulin and Insulin-like growth factor-1 associated cancers.-Chapter 4. Adipokines play important role in cell proliferation and antiproliferation -- Chapter 5. mTOR and AMP-activated protein kinase in obesity and cancer -- Chapter 6. Immune response and oxidative stress in obesity induced cancer -- Chapter 7. Role of gene polymorphism in obesity and cancer -- Chapter 8. Therapeutic role of green tea in obesity and cancer -- Chapter 9. Effect of dietary phytochemicals in obesity and cancer -- Chapter 10. Resveratrol as anti-obesity and anticancer agent -- Chapter 11. EGCG as anti-obesity and anticancer agent -- Chapter 12. miRNAs as therapeutic target in obesity and cancer -- Chapter 13. In silico updates on lead identification for obesity and cancer -- Chapter 14. In vivo models for obesity and obesity related carcinogenesis -- Chapter 15. Estrogen signaling based current and potential therapies against obesity and related diseases -- Chapter 16. Autophagy at the crossroad of obesity mediated cancer progression.
    Abstract: This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry. .
    Type of Medium: Online Resource
    Pages: IX, 361 p. 38 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618468
    DDC: 571.978
    Language: English
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  • 15
    Keywords: Bioinformatics. ; Biology Technique. ; Life sciences. ; Bioinformatics. ; Computational and Systems Biology. ; Biological Techniques. ; Life Sciences.
    Description / Table of Contents: Chapter 1. Prelusion Significance of Livestock -- Chapter 2. Mass Balance concept in Livestock Farming -- Chapter 3. Goat and Sheep Farming -- Chapter 4. Cattle and Buffaloes Farming -- Chapter 5. Factors Influencing Livestock Way of Life -- Chapter 6. Sustainable Livestock Farming -- Chapter 7. Conceptual Development of Livestock Supply Chain Management.
    Abstract: Basic principles of applied life sciences such as recombinant DNA technology is used in most life sciences industries marketing bio-formulations for designing more effective protein-based drugs, such as erythropoietin and fast-acting insulin etc. In recent times genetically engineered host cells from mammal, animal and plants are also being used in life sciences industries to manufacture biologics. This book discusses the most basic as well advanced issues on biological products for successfully managing a life sciences industry. It elucidates the life cycle of biological molecules, right from the conceptual development of different types of biopolymers, and their subsequent transfer from the conical flasks in laboratory to life sciences industries for large scale production and marketing. It focuses on sustainable longevity in the life cycle of commercial biopolymers. Cumulative facts and figures in this volume would immensely help in inspiring life sciences industry promoters to monitor value chain transfer process of biologics for better profitability. Additionally, it would serve as a perusal document for the students and researchers interested in entrepreneurial ventures or having their own start-up projects for the commercialization of biologics. .
    Type of Medium: Online Resource
    Pages: XVI, 207 p. 101 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811620515
    Series Statement: New Paradigms of Living Systems, 2
    DDC: 570.285
    Language: English
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  • 16
    Keywords: Zoology. ; Environment. ; Bioinformatics. ; Ecology . ; Biodiversity. ; Physical geography. ; Zoology. ; Environmental Sciences. ; Computational and Systems Biology. ; Ecology. ; Biodiversity. ; Earth System Sciences.
    Description / Table of Contents: Introduction -- Historical review of research on Arctic and Subarctic Aleocharinae -- Material and methods -- Impact of climate change on northern fauna and flora -- Aleocharinae as indicators of change -- Faunal analysis and discussion -- Key to tribes occurring in Arctic and Subarctic zones -- Tribe Gymnusini Heer, 1839 -- Tribe Aleocharini Fleming, 1821 -- Tribe Oxypodini C.G. Thomson, 1859 -- Tribe Tachyusini C.G. Thomson, 1859 -- Tribe Hypocyphtini Laporte, 1835 -- Tribe Myllaenini Ganglbauer, 1895 -- Tribe Liparocephalini Fenyes, 1918 -- Tribe Homalotini Heer, 1839 -- Tribe Placusini Mulsant and Rey, 1871 -- Tribe Athetini Casey, 1910 -- Tribe Falagriini Mulsant and Rey, 1873.
    Abstract: Arctic and Subarctic North America is particularly affected by climate change, where average temperatures are rising three times faster than the global average. Documenting the changing climate/environment of the north requires a structured knowledge of indicator taxa that reflect the effects of climate changes. Aleocharine beetles are a dominant group of forest insects, which are being used in many projects as indicators of environmental change. Many species are forest specialists restricted to certain microhabitats, some are generalists and others are open habitat specialists. They represent many ecological niches and, as such, are good indicators for many other species as well. The majority of Canadian aleocharine beetle species (about 600 spp.) has been studied and published by Jan Klimaszewski et al. (2018, 2020), mainly from southern, central, and western Canada, while the northern taxa remain poorly known and documented. The aim of the present book is to summarize the knowledge on this insect group in the Arctic and Subarctic North America and to provide a diagnostic and ecological tool for scientists studying and monitoring insects in northern Canada and Alaska. The book includes a review of the literature, information on 238 species and their habitats, taxonomic review, images, and identification tools.
    Type of Medium: Online Resource
    Pages: XIV, 712 p. 315 illus., 307 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030681913
    DDC: 590
    Language: English
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  • 17
    Keywords: Biomaterials. ; Nanotechnology. ; Biomedical engineering. ; Polymers. ; Microfluidics. ; Biomaterials. ; Nanotechnology. ; Biomedical Engineering and Bioengineering. ; Biomedical Materials. ; Polymers. ; Microfluidics.
    Description / Table of Contents: Introduction to high resolution manufacturing from 2D to 3D/4D printing -- Technologies evolutions and Design Considerations -- Vat photopolymerization -- Stereolithography -- Digital Light Processing -- Continuous liquid interface production -- Materials -- Multi-photon polymerization -- 2PP -- Materials -- Powder bed fusion -- Selective Laser Sintering -- Materials -- Commodity Polymers -- Engineering Polymers -- High-Performance Polymers -- Thermoplastic Elastomers -- The role of fillers -- Ink-jet printing -- Polyjet printing -- Aerosol jet printing -- Materials -- Volumetric 3D printing -- Computed Axial Lithography -- Xolography -- Materials -- Impact on different research fields and case studies -- Biomedical applications -- Cells culture, Microfluidics, rapid diagnostic tools -- Electronic applications -- Sensors and biosensors, actuators, integrated circuits -- Energy applications -- Supercapacitors, Energy harvesting -- Photonic applications -- Woodpile structures, light guides, optical fiber -- Future outlook.
    Abstract: This book provides a comprehensive presentation of the most frequently used high resolution manufacturing techniques available, as well as the polymeric materials used for each of the techniques. Divided into two parts covering the technologies and materials used and the impact on different research fields and case studies, High Resolution Manufacturing from 2D to 3D/4D Printing: Applications in Engineering and Medicine addresses issues like throughput improvement by volumetric 3D printing and presenting novel applications and case studies. In addition, this book also covers the latest breakthrough developments and innovations to help readers understand the future applications of this technology across various disciplines, including biomedicine, electronics, energy, and photonics.
    Type of Medium: Online Resource
    Pages: X, 300 p. 128 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031137792
    DDC: 620.19
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomedical engineering. ; Radiology. ; Bioinformatics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Radiology. ; Computational and Systems Biology.
    Description / Table of Contents: Deep Learning in Medical Image Analysis -- Medical Image Synthesis via Deep Learning -- Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation -- Deep Learning Computer Aided Diagnosis for Breast Lesion in Digital Mammogram -- Decision support system for lung cancer using PET/CT and microscopic images -- Lesion Image Synthesis using DCGANs for Metastatic Liver Cancer Detection -- Retinopathy analysis based on deep convolution neural network -- Diagnosis of Glaucoma on retinal fundus images using deep learning: detection of nerve fiber layer defect and optic disc analysis -- Automatic segmentation of multiple organs on 3D CT images by using deep learning approaches -- Techniques and Applications in Skin OCT Analysis -- Deep Learning Technique for Musculoskeletal Analysis -- Index.
    Abstract: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
    Type of Medium: Online Resource
    Pages: VIII, 181 p. 131 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331283
    Series Statement: Advances in Experimental Medicine and Biology, 1213
    DDC: 660.6
    Language: English
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  • 19
    Keywords: Biotechnology. ; Food science. ; Biomaterials. ; Nanotechnology. ; Ceramic materials. ; Biotechnology. ; Food Science. ; Biomaterials. ; Nanotechnology. ; Ceramics.
    Description / Table of Contents: Carbon materials from various sources for composite materials -- Carbon Fibre Reinforced Polymer (CFRP) Composites: Machining Aspects and Opportunities for Manufacturing Industries -- Surface modification of graphene nanoplatelets (GNP) towards preparation of natural/synthetic rubber blend nanocomposites -- Mechanical properties of nanoclay composite materials -- Fireproof capability of rigid polyurethane foam based composite materials -- Structural behavior of composite materials in fire -- Natural resources based green composite materials -- Composite materials for wind turbine structure -- Electrochromic Smart Windows: An Energy-efficient Technology -- Graphitic Carbon Nitride/ Metal Oxides Nanocomposites and Their Applications in Engineering -- Application of Nanofiber-based Composites: Progressive Health Impact -- Polymer-based Nanocomposite: Recent Trends in Safety Assessments in biomedical applications -- Modern approach of hydroxyapatite based composites for biomedical applications -- Hybrid Composite in Orthopedic applications -- Polymer-based composite in biomedical applications -- Components of All-solid-state Ion-Selective Electrodes (AS-ISEs) -- Nanocellulose and Nanocellulose-based Composites for Food Applications -- Nanocomposite Materials in Food Packaging: Opportunities, Challenges and Safety Assessment -- Biodegradability and Composite Coatings: Past, Present and Future Prospects -- Nanocomposite Film for Food Packaging: Opening Doors to Future Applications -- Functional Chitosan-Based Composites for Potential Application in Food Industry -- Metal-insulator-metal as a biosensing platfrom .
    Abstract: Composite materials are formed when the combination of separate materials acquire new properties distinct from its components. They have a range of applications in fields such as mechanical and electrical engineering, food science and biomedicine and represent a fast-growing area of research. Composite Materials: Applications in Engineering, Biomedicine and Food Science provides an overview of current technologies and applications related to composite materials in these fields. Organized by discipline, the text encompasses a wide variety of composite materials, including polymer, ceramic, biomaterial, hydroxyapatite, nanofiber and green composites. Early chapters detail the enhanced mechanical, magnetic, dielectric properties of electrical and thermal conductive composite materials, which are essential in daily science. Subsequent chapters focus on filler or reinforcement materials, including carbon materials, hybrid materials and nanomaterials. Particular emphasis is placed on nanocomposite materials, as these have increasingly diverse field applications. Various manufacturing methods, such as the synthesis method and top-down/bottom-up manufacturing, are also discussed. Coverage of the recent progress, challenges and opportunities surrounding composite materials make this text a one-stop reference for engineers, scientists and researchers working in this exciting field.
    Type of Medium: Online Resource
    Pages: XI, 484 p. 213 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454890
    DDC: 660.6
    Language: English
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  • 20
    Keywords: Food science. ; Business Data processing. ; Bioinformatics. ; Food Engineering. ; Business Informatics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1 - Poultry and Egg Production: An Overview -- Chapter 2 - Egg formation and Embryonic Development: An Overview -- Chapter 3 - Chemometric for Spectroscopy-Based Poultry and Egg Research -- Part-I: Table Eggs -- Chapter 4 - Non-destructive Quality Assessment of Table Eggs for Online Sorting -- Part-II: Hatching Eggs -- Chapter 5 - Grading of Hatching Eggs -- Chapter 6 - Non-destructive Technologies for Embryo Gender Prediction -- Chapter 7 - Hatch Window Monitoring, Control and Management -- Chapter 8 -: Chick Embryo Grading: A Future Tool for Precision Poultry Production -- Chapter 9 - A Vision for Smart Poultry Production to Achieve Multiple SDGs.
    Abstract: This book discusses table and hatching eggs, quality-based grading of eggs, pre-incubation, incubation, hatching and post-hatch monitoring period, and how the next-generation management of these process can be enriched by informatics through non-destructive technologies, signal processing, machine learning, AI, IoT applications, etc. This book will be a beneficial resource for egg and poultry science researchers, avian biologists and ecologists, developmental biologists, agricultural engineers, advanced graduate and postgraduate students, and poultry production industry stakeholders.
    Type of Medium: Online Resource
    Pages: XIV, 156 p. 76 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811925566
    DDC: 664
    Language: English
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  • 21
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Nanobiotechnology. ; Biomedical engineering. ; Nanotechnology. ; Medical care. ; Materials. ; Detectors. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Nanotechnology. ; Health Care. ; Sensors and biosensors.
    Description / Table of Contents: 1.Recent development in detection systems for human viral pathogens from clinical samples with special reference to biosensors -- 2. Nano Biosensors For COVID – 19 -- 3. Electrochemical detection of cancer fingerprint: A systematic review on recent progress in extracellular vesicle research from lab to market -- 4. Nano-biosensors for diagnosing infectious and lifestyle-related disease of human: an update -- 5. Design and Analysis of One Dimensional Photonic Crystal Biosensor Device for Identification of Cancerous Cells -- 6. Smart nanobiosensing for COVID-19 diagnosis -- 7. Machine Learning-Enabled Biosensors in Clinical Decision Making -- 8. Recent Progress on the Development of Chemosensors -- 9. Medical Device & Equipment Sector in India: Towards Sophisticated Digital Healthcare Systems - An Overview -- 10. Application of Radio Pharmaceuticals in Diagnostics and Therapy.
    Abstract: This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare. .
    Type of Medium: Online Resource
    Pages: IX, 249 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811971303
    DDC: 620.5
    Language: English
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  • 22
    Keywords: Forestry. ; Nanotechnology. ; Botany. ; Biotechnology. ; Anatomy. ; Genetics. ; Forestry. ; Nanotechnology. ; Plant Science. ; Biotechnology. ; Anatomy. ; Genetics and Genomics.
    Description / Table of Contents: Preface -- Chapter. 1. Emerging nanomaterials for forestry and associated sectors: An overview -- Chapter. 2. Potential of Nanomaterials in Bio-Based Wood Adhesives: An Overview -- Chapter. 3. Nanomaterials to improve fire properties in wood and wood-based composite panels -- Chapter. 4. Wood Plastic Composites (WPC): Applications of Nanomaterials -- Chapter. 5. Nanomaterials to improve properties in wood-based composite panels -- Chapter. 6. Nanomaterials to improve the strength of wooden joints -- Chapter. 7. Application of nanomaterials for wood protection -- Chapter. 8. Nanocellulose in paper and board coating -- Chapter. 9. Green Materials for Radiation Shielding: An overview -- Chapter. 10. Formaldehyde emissions from wood-based composites: Effects of nanomaterials.
    Abstract: Bio-based materials, including those containing wood, will become increasingly important as we move to a bio-based economy. Among their many attributes, it is vitally important that these materials are renewable, sustainable with proper management and environmentally benign. Wood remains one of our most important bio-based materials. While it is an amazing material, wood still has negative attributes and drawbacks that can affect performance, including dimensional instability when wetted, vulnerability to fire and high temperatures, and susceptibility to biodeterioration. A variety of treatments have been developed to overcome these weaknesses. Among the most exciting of these treatments are nanomaterials. These materials have some exceptionally attractive properties for improving timber performance and have been the subject of intensive research over the past decade. There is a tremendous need for a single comprehensive source of information on this rapidly emerging subject with tremendous potential to enhance the performance of a variety of bio-based materials. This book contains 10 chapters, each compiled by different author(s) who are considered the top researcher(s) in their respective fields. The chapters begin with some basic background on nanomaterials and their synthesis, then explore different areas for potential applications and conclude with a review of the emerging questions about nanomaterial safety. The book is designed to provide the latest information and know-how on application and utilization of different nanomaterials to improve the properties of wood and wood-based composite panels. The contents cover some main topics in the industry including improving physical and mechanical properties, increasing resistance to biodegradation (including fungi and insects), developing wood-plastic composites (WPC), applying nanomaterials in paper and board industry, and emergence of transparent wood and radiation shielding. It also covers the use of nanomaterials to improve the performance of paints and finishes used for forest products. The book provides a single location for those interested in the field to begin.
    Type of Medium: Online Resource
    Pages: X, 362 p. 85 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031173783
    DDC: 634.9
    Language: English
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  • 23
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Forestry. ; Biology. ; Geology. ; Geotechnical engineering. ; Forestry. ; Biological Sciences. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: 1. Remote Sensing for Forest Inventory and Resources Assessment -- 2. Multiple Sensors and Platforms for Biophysical and Biochemical Characterizations of Various Ecosystem Types of Tropical Forests in Malaysia: Advance, Limitation and Opportunity -- 3. A Review on the Use of LiDAR Remote Sensing for Forest Landscape Restoration -- 4. Assessment and Modeling of Forest Biomass and Carbon Stock and Sequestration using Various Remote Sensing Sensor Systems -- 5. Spatial Modeling of Transport and Resources Accessibility for Protecting Forest Ecosystems Against Forest Fires -- 6. Assessment of Forest Aboveground Biomass Estimation from Superview-1 Satellite Image using Machine Learning Approaches -- 7. Floristic Distribution Modelling for Resource Partitioning of Four Native Tree Species in Azad Jammu and Kashmir (AJK), Pakistan using Maxent -- 8. Application of Remote Sensing Vegetation Indices for Forest Cover Assessments -- 9. Rainforest Assessment in Brunei Darussalam through Application of Remote Sensing -- 10. Rubber Trees and Biomass Estimation Using Remote Sensing Technology -- 11. The Use of Landsat TM Imagery for the Application of Rubber Tree Area and Stand Volume Predictive Models in Rubber Plantations in Selangor, Malaysia -- 12. Using Historical Disturbance Identified with LandTrendr in Google Earth Engine for Land Cover Mapping of Oil Palm Landscapes -- 13. Geospatial Technology - Unlocking the Management and Monitoring in Malaysian Mangrove Forests -- 14. Effect of Tidal Regime, Relative Sea Level and Wind Intensity on Changes of Mangrove Area using Remote Sensing Approach -- 15. Spatio-temporal Distribution of Mangrove at Kuala Sepetang Forest Reserve, Malaysia using Remotely-sensed Data -- 16. Determination of The Effect of Urban Forests and Other Green Areas on Surface Temperature in Antalya -- 17. Conceptualising the Citizen-Driven Urban Forest Framework to Improve Local Climate Condition: Geospatial Data Fusion and Numerical Simulation -- 18. State-of-the-Art on Airborne LiDAR Applications in the Field of Forest Engineering -- 19. Restoration of Damaged Forest and Roles of Remote Sensing -- 20. Recent Advances in UAV-based Structure-from-motion Photogrammetry for Aboveground Biomass and Carbon Storage Estimations in Forestry -- 21. Hyperspectral Identification of Selected Dipterocarp Montane at the Species Level -- 22. Tree Biophysical Parameters Retrieval from Multi-source Remote Sensing Data Fusion.
    Abstract: This edited book is a collection of information on recent advancements in remote sensing for forestry application. The main focus of this book is to address the novel applications in remote sensing in terms of recent techniques, sensors, methods and data collection. Remote sensing has been used for many decades. Today, remote sensing is heavily utilized in forest management, which is acquired from airborne and space-borne platforms using satellite data. In recent years, there have been rapid advances in the new types of sensors. The new generations of satellite sensors are introduced not only to provide important information on forest ecosystems, but also to improve the techniques and accuracies obtained by the traditional approaches. Researchers have become increasingly aware of the potential of remote sensing to address important forestry issues and challenges. The number of forestry publications using remote sensing has grown very rapidly, and this is noticeable with many recent technologies and applications. This book provides valuable source of reference to foresters, researchers, ecologists, climate change scientists and scholars who use remote sensing in their work. Furthermore, it serves as an academic book for undergraduate and graduate students of forestry, agriculture, natural resources and environmental sciences. The book demonstrates and engages the students how the new advancements in remote sensing technology and theory relate to the many real-world forestry applications. It gives readers deeper understanding on how remote sensing has come a long way and evolved into a mature science in the past five decades.
    Type of Medium: Online Resource
    Pages: XVII, 458 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811942006
    DDC: 634.9
    Language: English
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  • 24
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical genetics. ; Neurosciences. ; Bioinformatics. ; Medical Genetics. ; Neuroscience. ; Computational and Systems Biology.
    Description / Table of Contents: S-MEDUTA: Combining Balanced Scorecard with simulation and MCDA techniques for the evaluation of the strategic performance of an Emergency Department -- An Architecture For Cooperative Mobile Health Applications -- An Educational Scenario for the Learning of the Conic Section: Studying the Ellipse with the Use of Digital Tools and Elements of Differentiated Instruction and Cognitive Neurosciences 45 -- Antibody clustering using a machine learning pipeline that fuses genetic, structural and physicochemical properties -- Neuroeducation and computer programming. A review -- Towards Analyzing Next Generation Sequencing Algorithms -- WOL Ecosystem: Secure remote power-state control of computer(s) over the internet for telemedicine purposes and dementia patients -- Epidemics Fuzzy Decision-Making Applications and Fuzzy Genetic Algorithms Efficiency Enhancement -- Multivariate data analysis and machine learning for prediction of MCI-to-AD conversion -- A Deep Learning Approach for Human Action Recognition using Skeletal Information -- Artificial Neural Networks in Computer Aided Drug Design. An overview of recent advances -- Computation of dolphins’ sound aspl while foraging -- Novel cost function definition for minimum-cost Tractography in MR Diffusion Tensor Imaging -- Platform for managing medical data by using a passive electronic device -- Evaluation of a computerized cognitive screening tool (ADPS, Altoida) in a sample of community-dwelling older adults -- Interconnections and Modeling Schemes of Kinesia Paradoxa -- Knowledge Discovery on IoT-enabled mHealth Applications -- Computational approaches applied in the field of neuroscience -- Drugena: A fully automated immunoinformatics platform for the design of antibody drug conjugates against neurodegenerative diseases -- Brain-Computer Interface Design and Neurofeedback Training in the case of ADHD Rehabilitation -- Particular biomolecular processes as computing paradigms -- Decision trees and applications -- Utilization of new technologies in the production of pharmaceutical olive oil -- A survey of evolutionary games in biology -- DTCo: An ensemble SSL algorithm for X-rays classification -- Cognitive Enhancement and Brain-Computer Interfaces. Potential Boundaries and Risks -- Informatics and cognitive assessment: a RUDAS scale paradigm -- Effective stochastic algorithm in disease prediction -- A Systems Biology Approach for the Identification of Active Molecular Pathways during the Progression of Alzheimer’s Disease -- A brief survey of the Prisoners' Dilemma game and its potential use in biology -- Validation of modeling and simulation methods in computational biology -- An improved self-labeled algorithm for cancer prediction -- eHealth application for e-bloodanalysis, e-diagnosis and digital diet guidance -- Modeling the critical activation of chaperone machinery in protein folding -- ANTISOMA: A computational pipeline for the reduction of the aggregation propensity of monoclonal antibodies -- A microscale mathematical blood flow model for understanding cardiovascular diseases -- Blockchain For Mobile Health Applications Acceleration With GPU Computing -- Finite Size Effects in Networks of Coupled Neurons -- Detecting common pathways and key molecules of Neurodegenerative Diseases from the topology of molecular networks -- Robotic Systems involved in the diagnosis of Neurodegenerative diseases -- Undergraduate Students’ Brain Activity in Visual and Textual Programming -- Fuzzy logic Systems and Medical Applications -- Apache Spark Implementations for String Patterns in DNA Sequences -- Big Data Analysis and Genetic Liability to Neuropsychiatric Disease -- Mathematical models and computer simulation of chemical carninogenesis process and its inhibition by antocarcinogenic substances -- Transitioning knowledge levels through problem-solving methods -- Cellular phone user’s age or the duration of calls moderate autonomic nervous system? A meta-analysis -- Logical Analysis and Validation of Publications in Bioinformatics.
    Abstract: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people. .
    Type of Medium: Online Resource
    Pages: XIII, 508 p. 129 illus., 100 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030326227
    Series Statement: Advances in Experimental Medicine and Biology, 1194
    DDC: 616.042
    Language: English
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  • 25
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant biotechnology. ; Nanotechnology. ; Biotechnology. ; Green chemistry. ; Chemistry, Organic. ; Agriculture. ; Plant Biotechnology. ; Nanotechnology. ; Biotechnology. ; Green Chemistry. ; Organic Chemistry. ; Agriculture.
    Description / Table of Contents: Preface -- Supercritical Fluid Technologies: A Green Solvent Approach for Pharmaceutical Product Development -- Supercritical Green Solvent for Amazonian Natural Resources -- Non-catalytic and catalytic supercritical water oxidation of phenol in the wastewaters of petroleum and other industries -- Production of Platform Chemicals using Supercritical Fluid Technology -- Supercritical carbon dioxide — a glimpse from the modern era of green chemistry -- Extraction of phenolic compounds by Supercritical fluid extraction -- The Application of Supercritical Carbon Dioxide in the Extraction of Biomolecules -- Chemistry of ionic liquid, switchable solvents, supercritical carbon dioxide and sub/supercritical water -- Applications of supercritical carbon dioxide in the rubber industry -- Compressed fluids for food by-products biorefinery -- Index.
    Abstract: Globalization and industrialization involve a number of reactions, products, extractions, and separations that require the use of organic solvents. These solvents are responsible for a number of ecological concerns, including atmospheric and land toxicity. Conventional organic solvents are regarded as volatile organic compounds; some are even limited due to their potential for ozone layer depletion. While supercritical liquids exhibit physical properties that could make them ideal substitutes for these volatile compounds, there is particular interest in the use of carbon dioxide as a solvent of crude material. In particular, carbon dioxide has apparent ‘green’ properties, like its noncombustible nature, the fact that it is generally nonpoisonous, and its relative inertness. Thus, the use of supercritical carbon dioxide can provide practical improvements to the sustainability of industrial products and processes. This book provides in-depth literature in the area of industrial green processes, focusing on the separation, purification, and extraction of compounds utilizing supercritical carbon dioxide as a green solvent.
    Type of Medium: Online Resource
    Pages: XIV, 245 p. 39 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030449841
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 631.52
    Language: English
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  • 26
    Keywords: Pharmaceutical chemistry. ; Medicinal chemistry. ; Nanochemistry. ; Biomaterials. ; Nanotechnology. ; Pharmaceutics. ; Medicinal Chemistry. ; Nanochemistry. ; Biomaterials. ; Nanotechnology.
    Description / Table of Contents: 1) Ganoderic acid for anticancer applications: Scope of nanomedicine in its effective delivery -- 2) Vitamin E based nanomedicines for anticancer drug delivery -- 3) Rutin based phytomedicines for cancer benefit -- 4) Nanoformulated Drug Delivery of Potential Betulinic Acid Derivatives: A Promising Approach toward Cancer Therapy -- 5) Quercetin Loaded Nanomedicine as Oncotherapy -- 6) Polyunsaturated fatty acids loaded nanomedicine for solid tumor -- 7) Rutin based phytomedicines for cancer benefit -- 8) Quercetin Loaded Nanomedicine as Oncotherapy -- 9) Quercetin Loaded Nanomedicine as Nutritional Applications -- 10) Polyphenols loaded nanomedicines against skin aging -- 11) Polyphenols loaded nanomedicines against skin aging -- 12) LIPID NANOCARRIERS FOR DERMAL DELIVERY OF LUTEIN -- 13) Bioactive flavonoid apigenin and its nanoformulations: a promising hope for diabetes and cancer -- 14) Therapeutic potential of ‘Aegeline’ an important phytochemical of Aegle marmelos: Current Health perspectives for the treatment of disease -- 15) EPIGALOCATECHIN-3-GALLATE LOADED NANOCARRIERS FOR HEALTH BENEFITS -- 16) Clove oil / Eugenol as the nanotechnological perspective for healthcare applications -- 17) Clove oil / Eugenol as the nanotechnological perspective for healthcare applications.
    Abstract: Nanotechnology is opening up new avenues in all scientific and technological fields. Among the novel applications, bioactives and nutraceuticals are fast-growing areas of nano research for better healthcare solutions. A variety of nanoformulations, such as polymeric nanoparticles, nanocapsules, nanoemulsions, transferosomes and ethosomes, liposomes, lipospheres, and lipid polymer hybrid nanoparticles have proved valuable in bioactive delivery and food materials. Further, new herbal drugs and nutraceuticals are reported to have remarkable advantages over conventional formulations of plant actives and extracts, including enhanced solubility, bioavailability, multiple drug delivery, greater stability, sustained delivery, improved tissue macrophage distribution, protection from toxicity, enhancement of pharmacological activity and protection from physical and chemical degradation. This book focuses on the advanced nanomaterials that are utilized for the encapsulation of nutrients/vitamin/phytoconstituents, as well as their other healthcare benefits. .
    Type of Medium: Online Resource
    Pages: XIII, 486 p. 132 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811516641
    DDC: 615.19
    Language: English
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  • 27
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Cancer. ; Biomedical Research. ; Bioinformatics. ; Cancer Biology.
    Description / Table of Contents: Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells.
    Abstract: With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.
    Type of Medium: Online Resource
    Pages: VIII, 247 p. 117 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811544941
    Series Statement: Advances in Experimental Medicine and Biology, 1255
    DDC: 610.72
    Language: English
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  • 28
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cytology. ; Stress (Physiology). ; Human physiology. ; Cancer. ; Diseases. ; Neurosciences. ; Nanotechnology. ; Cellular Stress. ; Human Physiology. ; Cancer Biology. ; Diseases. ; Neuroscience. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Oxidative stress and oral diseases -- Chapter 2. Role of Oxidative stress in Chronic Liver Diseases -- Chapter 3. In-vitro and In-vivo Antioxidant activity of nanoparticles -- Chapter 4. Oxidative stress in neurology and neurodegenerative processes -- Chapter 5. The role of oxidative stress in respiratory diseases -- Chapter 6. Role of Synbiotics in alleviating oxidative stress in colorectal cancer -- Chapter 7. Oxidative Stress and Immunological Complexities in Multi-Drug Resistant Tuberculosis -- Chapter 8. Infection-induced Oxidative Stress in Chronic Respiratory Diseases -- Chapter 9. Oxidative stress in neuropsychiatric and neurodegenerative diseases -- Chapter 10. Oxidative stress monitoring in in vitro and in vivo models -- Chapter 11. Effects of Yoga on Aging.
    Abstract: This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases. The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders. Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress. Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.
    Type of Medium: Online Resource
    Pages: X, 297 p. 48 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811515682
    DDC: 571.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Nanotechnology. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Nanotechnology. ; Biomedical Research.
    Description / Table of Contents: 1 Introduction -- 2 Barriers for tumor drug delivery -- 3 Tumor-targeted strategies -- 4 Tumor-responsive drug release strategies -- 5 Tumor diagnosis patterns -- 6 Tumor therapeutic modes -- 7 Carbon-based tumor-targeted systems -- 8 Silica-based tumor-targeted systems -- 9 Lipid-based tumor-targeted systems -- 10 Dendrimer-based tumor-targeted systems -- 11 Polymer-based tumor-targeted systems -- 12 Other new tumor-targeted systems -- 13 Clinical applications of tumor-targeted systems -- 14 Challenges and perspectives of tumor-targeted systems.
    Abstract: This book summarizes the latest advances in nanomaterials and techniques in the field of tumor-targeted diagnosis and therapy. It provides valuable information for beginners and senior researchers, and stimulates new research directions by offering novel and provocative insights into the properties and technical principles of nanomaterials. The book systemically discusses the challenges in tumor treatment, current tumor-targeted strategies, drug-release strategies, diagnosis and therapeutic patterns, and also explores newly developed multifunctional nanomaterials and related systems.
    Type of Medium: Online Resource
    Pages: VI, 463 p. 72 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811551598
    DDC: 571.978
    Language: English
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    Keywords: Botanical chemistry. ; Plant physiology. ; Bioinformatics. ; Plant ecology. ; Plant genetics. ; Plant Biochemistry. ; Plant Physiology. ; Computational and Systems Biology. ; Plant Ecology. ; Plant Genetics.
    Description / Table of Contents: Chapter 1. Plant Metabolomics: Current status and prospects -- Chapter 2. Plant Metabolites: Methods for Isolation, Purification and Characterization -- Chapter 3. Molecular markers and their application in the identification of elite germplasm -- Chapter 4. Cell and protoplast culture for production of plant metabolites -- Chapter 5. Hairy Root Culture: Secondary Metabolite Production in a Biotechnological Perspective -- Chapter 6. Methods for enhanced production of metabolites under in vitro conditions -- Chapter 7. Invasive alien plants: a potential source of unique metabolites -- Chapter 8. Modified Plant Metabolites as Nutraceuticals -- Chapter 9. Ethnomedicine and role of plant metabolites -- Chapter 10. Herbal Cosmeceuticals -- Chapter 11. Plant secondary metabolites as nutraceuticals -- Chapter 12. Bioactive secondary metabolites from lichens -- Chapter 13. Algal Metabolites and Phyco-medicine -- Chapter 14. Bioactive Metabolites in Gymnosperms -- Chapter 15. Flavonoids for Therapeutic Applications -- Chapter 16. Plant-based pigments: novel extraction technologies and applications -- Chapter 17. Plant Lectins: Sugar Binding Properties and Biotechnological Applications -- Chapter 18. Plant metabolites as Immunomodulators -- Chapter 19. Polyphenols: an overview of food sources and associated bioactivities -- Chapter 20. Plant metabolites against enteropathogens -- Chapter 21. Molecular chaperones and their applications -- Chapter 22. Bioprospecting of ethno-medicinal plants for wound healing.
    Abstract: Food security and the medicinal needs of billions of people around the world are pressing global issues, and the biodiversity and sustainable utilization of plants is of great significance in this context. Further, ethnobotanical studies are vital in the discovery of new drugs from indigenous medicinal plants, and plants with industrially important metabolites need to be cultivated to meet the growing market demand. In addition, the production of plant metabolites under in vitro conditions also has tremendous possibilities. The totipotency of plant cells plays a valuable role in the sustainable utilization of plant resources through cell, tissue and organ culture. At the same time, production can be enhanced using productive cell lines, treatment with elicitors, changing nutritional parameters and metabolic engineering. This book provides state-of-the-art information on biodiversity, conservation, ethnobotany, various aspects of In vitro secondary metabolite production, bioprospecting from various plant groups and drug discovery. It also discusses methods of extracting and characterizing drug leads from plant sources.
    Type of Medium: Online Resource
    Pages: XVIII, 581 p. 115 illus., 86 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811551369
    DDC: 572.2
    Language: English
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    Keywords: Human physiology. ; Nanotechnology. ; Cancer. ; Nanochemistry. ; Bacteria. ; Human Physiology. ; Nanotechnology. ; Cancer Biology. ; Nanochemistry. ; Bacteria.
    Description / Table of Contents: Chapter 1. Research Progression on Studies Related to Green Synthesis Nanoparticles: A Bibliometric Review -- Chapter 2. Current Green Nanotechnology: The Case of Noble Metal Nanocomposites and Applications -- Chapter 3. Role of Solvent System in Green Synthesis of Nanoparticles -- Chapter 4. Surface Engineering Techniques Associated with Stability, Biocompatibility and Toxicity of Nanoparticles -- Chapter 5. Role of Light in the Improvement of Nanoparticles Synthesis -- Chapter 6. Application of Nanomaterials for Cancer Diagnosis and Therapy -- Chapter 7. Marine Resources for Biosynthesis and Surface Modification of Anticancer Nanoparticles -- Chapter 8. Green Synthesis of Nanoparticles and Their Application in Cancer Therapy -- Chapter 9. Gold Nanoparticles: Biogenic Synthesis and Anticancer Application -- Chapter 10. Toxicity and Synthesis of Bacteriogenic Silver Nanoparticles Against Bacterial Pathogens: A Critical Review -- Chapter 11. Green Synthesis of Selenium Nanoparticles (SeNPs) via Environment-Friendly Biological Entities -- Chapter 12. Biogenic Synthesis, Characterization, Toxicity Assessment, Antiparasitic and Antibacterial Activities of Silver Nanoparticle from Lippia Multiflora -- Chapter 13. Green Synthesis of MgO Nanoparticles and its Effect on Chlorophyll Content in Plant Tissue Culture -- Chapter 14. Application of Green Nano-silica in Civil Engineering. .
    Abstract: This book describes various strategies for the synthesis of green nanoparticles using plant extracts and microbes, including the advantages and disadvantages of different methods and their applications. After discussing strategies for and the potential of green synthesis of noble metal nanoparticles, it highlights the role of the solvent system. The book then explores the stability/toxicity of nanoparticles and the associated-surface engineering techniques for achieving biocompatibility, and examines the antimicrobial efficacy of green nanoparticles with regard to various bacterial pathogens, as well as the underlying cytotoxicity mechanisms. Lastly, the book addresses the potential applications of various green nanoparticles in cancer theranostics, and reviews a number of plant-mediated nanoparticles as potential pharmaceutical agents. Given its scope, the book will be of interest to all scientists and students wanting to learn more about the synthesis and applications of green nanoparticles.
    Type of Medium: Online Resource
    Pages: XV, 316 p. 78 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811551796
    DDC: 612
    Language: English
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    Keywords: Botany. ; Agriculture. ; Agronomy. ; Biotechnology. ; Nanotechnology. ; Plant Science. ; Agriculture. ; Agronomy. ; Biotechnology. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Agrochemicals in Soil and Environment: An Overview -- Chapter 2. Agrochemicals- Provenance, Environmental Fate and Remediation Measures -- Chapter 3. Impact of Agrochemicals on Soil Microbiota -- Chapter 4. Agriculture Pollution in Kerala, India with Special Reference to Endosulphan -- Chapter 5. An Intergenerational Community-Based Approach to Safe Farming and Environmental Health -- Chapter 6. Guidance on Pesticides Handling in Farming -- Chapter 7. Impact of Pesticides, Herbicides and Insecticides on the Ecosystem -- Chapter 8. Pesticides and its Effects on Plants: A Case Study of Deltamethrin -- Chapter 9. The Use of Glyphosate in Regions of Argentina and Colombia and its Socio-environmental Impacts -- Chapter 10. Impact of Insecticides on Soil and Environment and their Management Strategies -- Chapter 11. Role of Insect Pest Management in Agriculture Conservation -- Chapter 12. Mobility of Trace Elements in Agricultural Soils- Chapter 13. The effects of nutrient enrichment on nutrient-poor ecosystems: Insights from the study of serpentine soil plant relations -- Chapter 14. Soil Erosion and Sedimentation - A Source of Contamination and Impact on Agriculture Productivity -- Chapter 15. Plastics in the Soil Environment: An Overview -- Chapter 16. Lead and cadmium contamination in the soil environment: Impacts on plant growth and human health -- Chapter 17. Heavy metals contamination on farmlands in the crude oil exploration area -- Chapter 18. Effect of Trace Elements in Soils and Its Management -- Chapter 19. Remediation of Agrochemicals in Soil and Environment -- Chapter 20. Alleviation in the Toxicity of Heavy Metals on Agricultural Crops by Metal Resistant Bacteria -- Chapter 21. Bioremediation Strategies to Mitigate the Impact of Atrazine in the Environment: Recent Advances and Prospects. Chapter 22. Aspergillus Mediated Bioremediation of Agrochemicals- Current Progress and Future Perspectives -- Chapter 23. Implications of Phytohormones as Agro-chemicals under Dynamic Environmental Conditions -- Chapter 24. Role of Genetically Modified Bacteria for Alleviating of Agrochemical Impact on the Environment -- Chapter 25. ‘Omics Perspective’ - Molecular Blue-print for Agrochemical Remediation -- Chapter 26. Impact and Remediation of Agrochemicals in Soil and Environment: Conclusions and Future Perspectives.
    Abstract: This volume ‘Agrochemicals in Soil and Environment: Impacts and Remediation’ is a comprehensive collection of important literature on agrochemical contamination. The main focus of this book is to point out undesirable changes in biological, physical and chemical characteristics of agricultural soils and its impacts on global agricultural crop productivity. Soil is one of the important resources of basic needs for our sustenance but due to various anthropogenic activities like urbanization and industrialization, the soil is losing its basic quality characteristics. Soil microorganisms, water holding capacity, minerals, salts and nutrients are under the direct threat due to agrochemicals therefore, agricultural sector is facing a serious challenge. Lack of proper knowledge and luxurious applications of agrochemicals resulting into degradation and deterioration of soil quality, loss of soil and crop productivity and threatening the food security. Therefore, it is imperative to develop indices, indicators and soil parameters for the monitoring and impact assessment of agricultural contaminants. Further, biotic and abiotic stresses and their tolerance mechanisms in plants in relation to the soil contaminants such as toxic pollutants, heavy metals, inorganic and organic matters, variety of pesticides, insecticides, herbicides, agricultural runoffs and solid wastes, and chemical fertilizers are also highlighted in this volume. This book also discusses causes of reduced agriculture productivity and suggests sustainable measures such as plant-based technologies, bioremediation and nanotechnology, that can be used to overcome the crop losses. The book is interest to research students, teachers, agricultural scientists, agronomists, environmentalists as well as policy makers.
    Type of Medium: Online Resource
    Pages: XXVI, 612 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811693106
    DDC: 580
    Language: English
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    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Opportunities for real time monitoring of biomolecules using FRET-based nanosensors -- Chapter 2. Current status of nanosensors in biological sciences -- Chapter 3. Biosensor: An Approach Towards a Sustainable Environment -- Chapter 4. Nanobiosensor in health sector: The milestones achieved and future prospects -- Chapter 5. Nanosensors based on DNA as an emerging technology for the detection of disease -- Chapter 6. Genetically Encoded Nanobiosensors for Nutrients and their applications -- Chapter 7. Development of highly sensitive optical sensors based on Carbon Nanotube (CNTs) -- Chapter 8. Recent advances of Fluorescent Resonance Energy Transfer-based nanosensors for the detection of human ailments -- Chapter 9. Application Of Nanosensors in Agriculture and Food Processing -- Chapter 10. Fluorescent Protein pairs and their application in FRET-based Nanobiosensors -- Chapter 11. Probes for Detection of Free Radicles -- .
    Abstract: This informative book compiles the most up-to-date applications of nanobiosensors in fields ranging from agriculture to medicine. The introductory section describes different types of nanobiosensors and use of nanobiosensors towards a sustainable environment. The applications are divided into four broad sections for easy reading and understanding. The book discusses how manipulation, control and integration of atoms and molecules are used to form materials, structures, devices and systems in nano-scale. Chapters in the book shed light on the use of nanosensors in diagnostics and medical devices. Application in food processing as well as in cell signaling is also described. Nanobiosensors have immense use, and this book captures the most important ones.
    Type of Medium: Online Resource
    Pages: XI, 223 p. 65 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811583469
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Bioinformatics. ; Medical genetics. ; Biotechnology. ; Computational and Systems Biology. ; Medical Genetics.
    Description / Table of Contents: Chapter 1: Global Alignment of PPI Networks -- Chapter 2: Integrated Network-Based Computational Analysis for Drug Development -- Chapter 3: Effective Random Walk Models for Comparative Network Analysis -- Chapter 4: Computational Methods for Protein-Protein Interaction Network Alignment -- Chapter 5: Network Propagation for the Analysis of Multi_Omics Data -- Chapter 6: Motifs in Biological Networks -- Chapter 7: Bio Fabric Visualization of Network Alignments -- Chapter 8: Module Identification of Biological Networks via Graph Partition -- Chapter 9: Network Module Detection to Decipher the Heterogeneity of Cancer Mutations.
    Abstract: This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights. .
    Type of Medium: Online Resource
    Pages: XII, 217 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571733
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Food science. ; Materials. ; Detectors. ; Nanotechnology. ; Nanoelectromechanical systems. ; Food Science. ; Sensors and biosensors. ; Food Nanotechnology. ; Nanoscale Devices.
    Description / Table of Contents: Chapter 1. Introduction to Nanobiosensing Technologies and Nanobioanalytical Systems -- Chapter 2. Application of Nanotechnology in Food Analysis -- Chapter 3. Nanoengineered Aptamer Assisted Strategies for the Detection of Food-borne Pathogens -- Chapter 4. Electrochemical Sensors for Food Adulterants -- Chapter 5. Fluorescent Biosensing and Chemosensing Strategies for Food Quality Assessment -- Chapter 6. Optical Detection of Targets for Food Quality Assessment -- Chapter 7. Conventional Technologies and Opto-Electronic Devices for Detection of Food Biomarkers -- Chapter 8. Applications of Intelligent Packaging for Meat Products -- Chapter 9. RFID Near-Field Communication (NFC)-based Sensing Technology in Food Quality Control -- Chapter 10. Advances in Biosensing Technology in the Pharmaceutical Industry -- Chapter 11. Sensor Systems For Drug Analysis and Their Interferences -- Chapter 12. Biosensors for the Detection of Spoilage Levels and Excess Preservatives in Seafood -- Chapter 13. Utilising Big Data as Analytical Tool for Food Safety Applications -- Chapter 14. Aptamer Based Miniaturized Technology for Drug Analysis.
    Abstract: This book reviews applications of nanomaterial and nanodevices in the food industry. It also discusses the advanced bioanalytical techniques, including Enzyme-Linked Immunosorbent Assay (ELISA), immunoanalytical techniques, and monoclonal antibody-based immunological techniques for detecting food adulterations and allergens. It comprehensively covers electrode modification and nano-engineered fabrication of biosensors to enhance their functionalities for utilization in food industries. The book highlights the utilization of nanobiosensors for food safety and quality analysis, such as detection of toxin, food-borne pathogen, allergen, evaluation of toxicity etc. Further, it also summarizes the recent advances in nanodevices such as nano-systems, nano-emulsions, nanopesticides, and nanocapsules and their applications in the food industry. Lastly, it covers nanomaterial-based sensors for drug analysis in diverse matrices. It serves as an invaluable source of information for professionals, researchers, academicians, and students related to food science and technology.
    Type of Medium: Online Resource
    Pages: XII, 360 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811683336
    DDC: 641.3
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Plant anatomy. ; Plants Evolution. ; Plant ecology. ; Plant physiology. ; Plants Reproduction. ; Computational and Systems Biology. ; Plant Anatomy and Morphology. ; Plant Evolution. ; Plant Ecology. ; Plant Physiology. ; Plant Reproduction.
    Description / Table of Contents: Preface -- Acknowledgements -- Introduction: Collecting, Observing, and Describing the Natural World -- Scientific Ferment in late Eighteenth Century Edinburgh -- Scientific Exploration During Voyages of Discovery -- ... the plants of Scotland might be equally useful -- Travels in the Interior Districts of Africa -- A good practical Botanist -- So remote a country as New Holland -- The Crew labouring under the Same disorder -- Mungo Park's Last Journey -- A Tedious and Uncomfortable Passage -- Prodrommus, Florae Novae Hollndiae -- Banks's Librarian -- Taking leave of Sir Joseph Banks -- Pollen Grains of Clarkis pulchella -- Epilogue: The greatest of Banksian botanist-librarians -- Bibliography.
    Abstract: Explorer-naturalists Robert Brown and Mungo Park played a pivotal role in the development of natural history and exploration in the late eighteenth and early nineteenth centuries. This work is a fresh examination of the lives and careers of Brown and Park and their impact on natural history and exploration. Brown and Park were part of a group of intrepid naturalists who brought back some of the flora and fauna they encountered, drawings of what they observed, and most importantly, their ideas. The educated public back home was able to gain an understanding of the diversity in nature. This eventually led to the development of new ways of regarding the natural world and the eventual development of a coherent theory of organic evolution. This book considers these naturalists, Brown, Park, and their contemporaries, from the perspective of the Scottish Enlightenment. Brown’s investigations in natural history created a fertile environment for breakthroughs in taxonomy, cytology, and eventually evolution. Brown’s pioneering work in plant taxonomy allowed biologists to look at the animal and plant kingdoms differently. Park’s adventures stimulated significant discoveries in exploration. Brown and Park’s adventures formed a bridge to such journeys as Charles Darwin’s voyage on H.M.S. Beagle, which led to a revolution in biology and full explication of the theory of evolution.
    Type of Medium: Online Resource
    Pages: XIX, 217 p. 39 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030748593
    Series Statement: Memoirs of The New York Botanical Garden, 122
    DDC: 570.285
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Bioinformatics. ; Biology Technique. ; Genomics. ; Gene expression. ; Agriculture. ; Computational and Systems Biology. ; Genomic Analysis. ; Gene Expression Analysis. ; Agriculture.
    Description / Table of Contents: Chapter 1_Introduction to Bioinformatics -- Chapter 2_Statistics for bioinformatics -- Chapter 3_ Introduction of the databases of rice -- Chapter 4_Brief insight into the evolutionary history and domestication of wild rice relatives -- Chapter 5_3000 Genome project- A brief insight -- Chapter 6_ Databases and bioinformatics tools for data mining -- Chapter 7_Sequence Alignment -- Chapter 8_Gene identification and structure Annotation -- Chapter 9_Phylogenetic Analysis -- Chapter 10_RNA Structure Prediction. -Chapter 11_Structural Proteomics -- Chapter 12_Gene ontology and pathway enrichment analysis -- Chapter 13_High throughput sequencing technologies -- Chapter 14_Mapping algorithms in high-throughput sequencing -- Chapter 15_DNA–Protein Interaction Analysis (ChIP-Seq) -- Chapter 16_RNA–Protein Interaction Analysis -- Chapter 17_SNP Identification and Discovery -- Chapter 18_Microsatellite Markers from whole genome and Transcriptomic Sequences. - Chapter 19_Genome-wide association study -- Chapter 20_Expression Profiling and Discovery of microRNA -- Chapter 21_Computational approaches in identifying long non-coding RNA -- Chapter 22_circRNA in rice -- Chapter 23_ Metagenomics -- Chapter 24_RNA-Induced Gene Silencing -- Chapter 25_Single-cell RNA sequencing technologies -- Chapter 26_Recent Advancement in NGS Technologies.
    Abstract: This book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment. In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions, and molecular markers, including SNP and microsatellites, in the contexts of rice breeding and genetics. Lastly, it explores various tools that are used to identify and characterize non-coding RNA in rice and their potential role in rice research.
    Type of Medium: Online Resource
    Pages: XVI, 609 p. 49 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811639937
    DDC: 570.285
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Bioinformatics. ; Genomics. ; Botany. ; Computational and Systems Biology. ; Genomics. ; Plant Science.
    Description / Table of Contents: Chapter-1 Possibility of Uncoding Structural Organization of Genome in Rice: Prospects and Approaches By 3D Genome Sequencing -- Chapter-2 Bioinformatics Approaches for High Density Linkage Mapping in Rice Research -- Chapter-3 Quantitative Trait Locus Mapping in Rice -- Chapter-4 Metabolomics in Rice Improvement -- Chapter-5 Computational Approaches Towards Decoding the Extra Chromosomal Genome of Rice -- Chapter-6 Computational Epigenetics in Rice Research -- Chapter-7 Computational Approaches Towards Understanding Stress in Rice -- Chapter-8 Identifying Complex Polyploidy Genomes Using Bioinformatics Approaches -- Chapter-9 Perspectives and Challenges of Phenotyping in Rice -- Chapter-10 The CRISPR Technology and Application in Rice -- Chapter-11 De Novo Evolution of Genes in Rice -- Chapter-12 Artificial intelligence and machine learning in rice research -- Chapter-13 Intellectual Property and Rice Research -- Chapter-14 Plant Pathogen Co-Evolution in Rice -- Chapter-15 Conservation of Rice Germplasm by Bioinformatics Strategy -- Chapter-16 Recent Advances in Multi-Omics and Breeding Approaches Towards Drought Tolerance in Crops.
    Abstract: This book summarizes the advanced computational methods for mapping high-density linkages and quantitative trait loci in the rice genome. It also discusses the tools for analyzing metabolomics, identifying complex polyploidy genomes, and decoding the extrachromosomal genome in rice. Further, the book highlights the application of CRISPR-Cas technology and methods for understanding the evolutionary development and the de novo evolution of genes in rice. Lastly, it discusses the role of artificial intelligence and machine learning in rice research and computational tools to analyze plant-pathogen co-evolution in rice crops.
    Type of Medium: Online Resource
    Pages: XV, 359 p. 21 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811639975
    DDC: 570.285
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmacy. ; Bioinformatics. ; Pharmacology. ; Pharmacy. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. 'Network Target' Theory and Network Pharmacology -- Chapter 2. Application of Network Pharmacology Based on Artificial Intelligence Algorithm in Drug R & D -- Chapter 3. Commonly used Network Pharmacology Database -- Chapter 4. Commonly used Network Pharmacology Software -- Chapter 5. Network Pharmacology and TCM Modernization Case Studies -- Chapter 6. Network Pharmacology and Modern Drug R & D Cases -- Chapter 7. Drug-based Network Pharmacology Practice Process -- Chapter 8. Disease-based Network Pharmacology Practice Process -- Chapter 9. Drug-disease-based Network Pharmacology Practice Process.
    Abstract: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 163 illus., 119 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811607530
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Bioinformatics. ; Botanical chemistry. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture. ; Bioinformatics. ; Plant Biochemistry.
    Description / Table of Contents: Chapter 1. Sandalwood: The King of Aroma in Plant Kingdom -- Chapter 2. Historical and Cultural Importance of Sandalwood in India and Its Role in Conservation of Natural Populations -- Chapter 3. Sandalwood: Traditional Knowledge from Ayurveda -- Chapter 4. Genomic Resources in Indian Sandalwood: Implications in Conservation and Breeding -- Chapter 5. Whole Genome Sequence of Sandalwood and Its Comparative Study -- Chapter 6. Mining of SSRs and SNPs in Sandalwood Genome -- Chapter 7. Sandalwood Fragrance Pathway and Its Engineering for Sustainable Production of High-Value Santalols -- Chapter 8. Sandalwood Essential Oil and Its Phyto-Chemistry -- Chapter 9. Scope of Proteogenomic Analysis for Indian Sandalwood (Santalum album) -- Chapter 10. Future Prospects of Sandalwood Research.
    Abstract: This book is the first comprehensive compilation describing the importance of sandalwood in national and international markets, genetic resources, molecular markers, whole genome sequencing, and pathway genes involved in oil biosynthesis, aroma and fragrance. Application of various “omics” approaches in delineating genome architecture and annotation of genes is highlighted. This book comprises 10 chapters covered over 200 pages authored by the researchers involved in sandalwood genomics. The sandalwood, Santalum album is known for its unique fragrance and finest wood available for carving. Also, sandalwood is intertwined with Indian culture and it is the second most valuable and expensive tree in the world.
    Type of Medium: Online Resource
    Pages: XVIII, 103 p. 26 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030933944
    Series Statement: Compendium of Plant Genomes,
    DDC: 581.35
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Drugs Design. ; Pharmaceutical chemistry. ; Genomics. ; Bioinformatics. ; Biomedical Research. ; Structure-Based Drug Design. ; Pharmaceutics. ; Genomics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Emerging Technologies : Gateway to Understand Molecular Insight of Diseases, Newer Drugs, Their Design and Targeting -- Chapter 2. Polypharmacology: New Paradigms in Drug Development -- Chapter 3. Drug Repurposing in Biomedical Research : Benefits and Challenges -- Chapter 4. Computational Methods for Drug Repurposing -- Chapter 5. Genomic Approaches for Drug Repositioning -- Chapter 6. Organ-On-A- Chip: Novel in-Vitro Model For Drug Discovery -- Chapter 7. Precision Radiomolecular Oncology: Challenging the Classical Statistical Evidence Based Medicine -- Chapter 8. Drug Repositioning of the Phenylpiperazine Derivative Naftopidil in Prostate Cancer Treatment -- Chapter 9. Biomarker Based Drug Discovery and Reverse Translational Approach -- Chapter 10. Nanotechnology in Dentistry -- Chapter 11. Nanoparticles a Potential Breakthrough in Counteracting Multidrug-Resistant Bacterial Infections: A Holistic View on Underlying Mechanisms and Antibacterial Properties -- Chapter 12. Emerging Role of Cannabinoid System Modulators in Treatment of Cancer -- Chapter 13. Nanodrugs : A Futuristic Approach for Treating Nephrolithiasis -- Chapter 14. Lipo Dermaceuticals : Technological Transformation -- Chapter 15. The Importance of Drug Dose Adjustment in Elderly Patients with Special Considerations for Patients on Diverse Co-Medications and Antidepressants -- Chapter 16. Role of Microfluidics and Nano Fluidics in Managing CAD -- Chapter 17. Targeted Gene Delivery Through Magnetofection: The New Face of Medicine -- Chapter 18. Qbd-Steered Systematic Development of Drug Delivery Nanoconstructs : Vital Precepts, Retrospect and Prospects -- Chapter 19. Nanoemulsions: A Potential Advanced Nanocarrier Platform for Herbal Drug Delivery -- Chapter 20. Sirna Encapsulated Nanoparticles for Targeting Dorsal Root Ganglion (Drg) in Diabetic Neuropathic Pain -- Chapter 21. EGFR Targeted Quinazoline Clubbed Heterocycles as Anti-Cancer Agents. Chapter 22. Therapeutic Human Monoclonal Antibodies -- Chapter 23. Hydroxyapatites and Their Biomedical Applications -- Chapter 24. Recent Progress in Applications of Magnetic Nanoparticles in Medicine: A Review -- Chapter 25. Chimeric Antigen Receptor T-Cell Therapy: A Cutting Edge Therapy for Multiple Myeloma -- Chapter 26. Nanoparticles-Associated Lipopeptides: A New Class of Antimicrobials -- Chapter 27. Antimicrobial Applications of Engineered Metal-Based Nanomaterials -- Chapter 28. Strengthening Immunity-Ayurveda & Medicinal Plants -- Chapter 29. The Pathophysiology of Liver Disorders and Pharmacotherapy Options with Special Reference to Traditional Herbal Medicines: A Comprehensive Review -- Chapter 30. Polymeric Vehicles for Controlled Delivery of Ayurvedic Drugs for Wound Management.
    Abstract: This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.
    Type of Medium: Online Resource
    Pages: XII, 599 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692321
    DDC: 610.72
    Language: English
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  • 43
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botanical chemistry. ; Nanobiotechnology. ; Plant physiology. ; Green chemistry. ; Agricultural biotechnology. ; Nanotechnology. ; Food science. ; Plant Biochemistry. ; Nanobiotechnology. ; Plant Physiology. ; Green Chemistry. ; Agricultural Biotechnology. ; Food Nanotechnology.
    Description / Table of Contents: Chapter 1. Emerging trends of Nanoparticles in Sustainable Agriculture: Current and Future Perspectives -- Chapter 2.Nanoparticles in Plant Disease Management -- Chapter 3.Proteomics of Plant Nanoparticles Interaction Mechanism -- Chapter 4. Importance of the secondary metabolites and biological parameters modification by metallic, oxides, and carbon-based nanomaterials over forage plants -- Chapter 5. Polymer-based nanoparticles (NPs): A promising approach for crops productivity -- Chapter 6.Plant mediated eco-friendly synthesis of platinum nanoparticles and their applications -- Chapter 7.Foliar Application of Metallic Nanoparticles on Crops Under Field Conditions -- Chapter 8.Phytotoxic effects of nanoparticles and defense mechanisms in plants -- Chapter 9.Plant Molecular Responses to Nanoparticle Stress -- Chapter 10. Nanoelicitation: A Promising and Emerging Technology for Triggering the Sustainable In Vitro Production of Secondary Metabolites in Medicinal Plants -- Chapter 11. Nanomaterials as unique carriers in agricultural practices for plant growth and development: A state of current knowledge -- Chapter 12. Nanotechnologies and Sustainable agriculture for Food and Nutraceutical production: An Update -- Chapter 13. Green synthesis of plant assisted manganese-based nanoparticles and their various applications -- Chapter 14.Biogenic synthesis of lead-based nanoparticles and their recent applications.
    Abstract: This book explores the interactions between nanomaterials/nanoparticles and plants and unveils potential applications. The chapters emphasize the implications of nanoparticles in cross-discipline approaches, including agricultural science, plant physiology, plant biotechnology, material science, environmental science, food chemistry, biomedical science, etc. It presents recent advances in experimental and theoretical studies and gives in-depth insights into the interaction between nanoparticles and plant cells. In addition, it discusses the potential applications and concerns of nanoparticles comprehensively. The research field of plant nanotechnology has great potential within plant sciences and agriculture and the related research is getting increased at present. The study of plant nanotechnology receives an advantage from the great progress of nanotechnology in biomedical sciences particularly the well-development of a variety of biocompatible nanoparticles (NPs) and advanced analytical techniques. Nowadays, although some NPs have been applied in the studies of plant and agronomic sciences, the knowledge regarding physiology and underlying mechanisms within the plant cell remains limited. This book offers a critical reference for students, teachers, professionals, and a wide array of researchers in plant science, plant physiology, plant biotechnology, material science, environmental science, food chemistry, nanotechnology, and biomedical science. It could also benefit the related field of plant nanotechnology for designing and organizing future research. .
    Type of Medium: Online Resource
    Pages: VII, 426 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811925030
    DDC: 572.2
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Genetics. ; Genetic transcription. ; Molecular biology. ; Bioinformatics. ; Genetics and Genomics. ; Gene Transcription. ; Molecular Biology. ; Bioinformatics.
    Description / Table of Contents: 1. What is the transcriptome and how it is evaluated? -- 2. ALTERNATIVE SPLICING OF PRE-MESSENGER RNA -- 3. Transcriptome Analysis Using RNA-seq and scRNA-seq -- 4. TRANSCRIPTOMICS OF NEONATAL AND INFANT HUMAN THYMUS -- 5. Transcriptomics at the single cell level and human diseases: opportunities and challenges in data processing and analysis -- 6. METHODS FOR GENE CO-EXPRESSION NETWORK VISUALIZATION AND ANALYSIS -- 7. Comparative Analysis of Packages and Algorithms for the Analysis of Spatially Resolved Transcriptomics Data -- 8. The Interplay Between the Transcriptomics and Proteomics Profiles -- 9. TRANSCRIPTOME DURING NORMAL CELL DIFFERENTIATION -- 10. Transcriptomics to dissect the Immune System -- 11. Transcriptome Profiling in Autoimmune Diseases -- 12. Transcriptome Profiling in Experimental Inflammatory Arthritis -- 13. TRANSCRIPTOMICS AND IMMUNE RESPONSE IN HUMAN CANCER -- 14. MicroRNAs in Cancer -- 15. Oxidative Stress, DNA Damage and Transcriptional Expression of DNA Repair and Stress Response Genes in Diabetes Mellitus -- 16. Large-scale gene expression in monogenic and complex genetic diseases -- 17. Transcriptome in Human Mycoses -- 18. Understanding Chagas Disease by Multi-omics data Integration, Functional and Enrichment Computational Analysis.
    Abstract: The study of transcriptomics is key to understanding complex diseases. This new edition will build on the foundation of the first edition while incorporating the progress that has been made in the field of transcriptomics in the past six years, including bioinformatics for data analysis. Written by leading experts, chapters address new subjects such as methodological advances in large-scale sequencing, the sequencing of single-cells, and spatial transcriptomics. The new edition will address how transcriptomics may be used in combination with genetic strategies to identify causative genes in monogenic and complex genetic diseases. Coverage will also explore transcriptomics in challenging groups of diseases, such as cancer, inflammation, bacterial infection, and autoimmune diseases. The updated volume will be useful for geneticists, genome biologists, biomedical researchers, molecular biologists, bioinformaticians, and students, among others.
    Type of Medium: Online Resource
    Pages: XI, 474 p. 67 illus., 62 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030878214
    DDC: 576.5
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical genetics. ; Neurosciences. ; Bioinformatics. ; Medical Genetics. ; Neuroscience. ; Computational and Systems Biology.
    Description / Table of Contents: 1-Stratification of patients with Chronic Obstructive Pulmonary Disease using Volatile Organic Compounds -- 2-Evidence-based Leadership: A Study of its Application to General Hospital of the Public Health System through the Implementation Leadership Scale -- 3-Greek nurses’ perception of hospital ethical climate. A cross-sectional study -- 4-Investigating the main causes of conflicts and the managements strategies are used by healthcare professionals. The case of general hospital of Arta -- 5-Incidence of deep vein thrombosis and its effect on health related quality of life among nurses of Greek public hospital. A multicenter study -- 6-Factors affecting anxiety and depression in caregivers of hemodialysis patients -- 7-Hand grip strength in patients on hemodialysis: An observational study -- 8-The effect of spirituality on illness perceptions in patients undergoing hemodialysis -- 9-Validation of the STOP-Bang Questionnaire in Greek patients suffering from obstructive sleep apnea -- 10-The role of Pythagorean Self-Awareness Intervention in obstructive sleep apnea. A randomized controlled trial -- 11-Tissue characterization in Cardiology. Moving beyond function -- 12-Psychiatric care in acute care units with locked doors: Nursing care providers’ perceptions and experiences -- 13-Researching nursing students’ attitudes towards mental health practice: cultural adaptation and validation of the Greek version of the Acceptability of Locking the Door Questionnaire in acute psychiatric care -- 14-Compliance of bronchial asthma patients' with the Mediterranean diet -- 15-Nurses’ experiences of psychiatric care in acute care units with an open door policy -- 16-Validation of the Greek Version of Hedonic, Eudaimonic and Extrinsic Motives for Activities (HEEMA) Instrument -- 17-Event-Related Rumination Inventory: A Validation Process in the Greek Language -- 18-The job rotation of nursing staff and its effects on nurse`s satisfaction and occupational engagement -- 19-The burden on carers with multiple sclerosis -- 20-Attitudes of the general population regarding patient information for a chronic and life-threatening disease. A cross-sectional study -- 21-Assessment of healthcare professionals’ knowledge and awareness on aspects related to ionizing radiation examinations in Athens, Greece -- 22-Medication errors and their correlation with nurse's satisfaction. The case of the hospitals of Lasithi, Crete -- 23-Health-Related Quality of Life and Living Costs of HIV-Infected Patients -- 24-Evaluation of anxiety and depression in women undergoing mastectomy in Greece -- 25-The effect of emotional intelligence on caring behaviors among psychiatric nurses in Greece -- 26-Investigating nursing leadership in intensive care units of hospitals of Northern Greece and its relationship to the working environment -- 27-Health-Related Quality of Life and Rehabilitation Costs of Patients with Amputated Limb -- 28-Anxiety and depression in hemodialysis: Sex differences -- 29-Patient knowledge, adherence to the therapeutic regimen, and quality of life in hemodialysis -- 30-The burden of caregivers of patients after hip replacement and its impact on the cost of living of the family -- 31-The effects of exercise in patients with Sarcopenia -- 32-Fluid dynamics derived parameters in coronary vessels -- 33-Level of knowledge about COPD among patients and caregivers -- 34-Increased body mass index (BMI) and sunscreen use are associated with inadequate vitamin D status in Greek adults in winter -- 35-The effect of whole-body cryostimulation in healthy adults -- 36-Exhaled Nitric Oxide (FeNO) in patients hospitalized for an exacerbation of bronchiectasis and/or COPD -- 37-Formulation and Evaluation of Dermatological product containing Niacinamide -- 38-Exhaled breath condensate and dyspnea in COPD -- 39-The Effects of Pythagorean Self-Awareness Intervention on Irritable Bowel Syndrome Patients: A Non-Randomized Controlled Trial -- 40-Adults’ stress response to unexpected oral and arithmetic tasks in supine position -- 41-Triangles and family engagement in drug and alcohol addiction treatment -- 42-Use of fortified bread for addressing vitamin D deficiency. .
    Abstract: The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The increase in the average length of life leads to the development of various diseases in the elderly population. This volume focuses on the sessions from the conference on Geriatrics.
    Type of Medium: Online Resource
    Pages: XXVII, 389 p. 27 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030787714
    Series Statement: Advances in Experimental Medicine and Biology, 1337
    DDC: 616.042
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biometry. ; Biomedical engineering. ; Bioinformatics. ; Biological models. ; Biostatistics. ; Biomedical Engineering and Bioengineering. ; Computational and Systems Biology. ; Biological Models.
    Description / Table of Contents: Forecasting of SARS-COV-2 dynamic: beyond the classical SIR model -- Derivation of OED methods for applications in cytogenetic biodosimetry -- Minimum Phi-divergence tests for ophthalmological data grouped in clusters -- Multimodality test for determining which genes distinguish oncological patients -- Exploring the relationship between different cancer sites using disease mapping models -- Advances in flow cytometry gating based on distances and divergences in probability spaces -- Application of quantile regression models for biomedical data -- Hippocampus shape analysis via skeletal models and kernel smoothing -- Methods for analysis of microbiome count data with applications -- The FMM model as a classifier of cardiovascular pathologies -- A novel statistical insight of the circadian markers that govern cardiac rhythms -- Sleep and circadian synchronization assessment from multivariate recordings. .
    Abstract: This book presents novel statistics methods and reproducible software that helps to solve challenging problems in biomedicine. Specifically, it consists of a collection of 11 chapters contributed by some of the leading experts in the mathematical and statistical field which address new challenges in very disparate biomedical areas, such as genomics, cancer, circadian biology, microbiome, mental disorders, and more. The mathematical rigor is written in a user-friendly way to serve a general biomedical audience ranging from trainees or students to doctors, as well as scientific researchers, university departments, and PhD students.
    Type of Medium: Online Resource
    Pages: XI, 276 p. 71 illus., 57 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031327292
    DDC: 570.15195
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Food science. ; Nanotechnology. ; Biomedical Research. ; Food Science. ; Food Engineering. ; Food Nanotechnology.
    Description / Table of Contents: Chapter 1. Chapter 1. Food packaging industry - An introduction -- Chapter 2. Toward Smarter Food Packaging -- Chapter 3. Novel packaging development, assessment and authentication using smart technologies, non-invasive biometric sensory tools, and artificial intelligence -- Chapter 4. Biodegradable packaging materials and techniques to improve their performance -- Chapter 5. Smart Freshness Indicator for Animal Based Products Packaging - Current Status.-Chapter 6. Packaging of dairy products-Emerging strategies -- Chapter 7. Functional packaging materials for fishery products applications -- Chapter 8. Edible films and coatings: Major challenges and potential applications in food Packaging: A Review.-Chapter 9. Role of sensors to improve food/beverage packaging -- Chapter 10. Functional nanomaterials for food packaging applications -- Chapter 11. Rules and regulations related with packaging.
    Abstract: This book reviews the science and technology of food packaging and covers the potential innovations in the food packaging sector. At the same time, it highlights the issues and prospects for linking the laboratory research to the market. In addition to typical packaging requirements such as food quality, shelf life, protection, communication, and marketing, the book emphasizes the need for novel packaging materials, including biodegradable packaging for a variety of food products. A wide range of food products has been kept in focus and includes animal-based food products such as dairy products and sea foods. The book presents the next level of packaging solutions i.e., smart packaging with the applications of potential tools such as intelligent and active packaging, and includes the latest research on emerging digital technologies for packaging development, assessment, and acceptability. It further highlights the strategies including blends, reinforcing agents, cold plasma, UV light applications, chemical, and enzymatic methods and explores the new opportunities leading to improvement in the packaging performance. Smart freshness indicator applications, including gas and time-temperature indicators for quality and safety of packaged products, have been covered in detail. The book also includes the functional characteristics of edible films and coatings, including their bioactive characteristics. Finally the book presents the rules and regulation related to packaging.
    Type of Medium: Online Resource
    Pages: XI, 286 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811671968
    DDC: 610.72
    Language: English
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    Keywords: Animal culture. ; Veterinary medicine. ; Anatomy, Comparative. ; Genetics. ; Bioinformatics. ; Animal Science. ; Veterinary Science. ; Animal Anatomy. ; Genetics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1_Global Duck Production: An Overview -- Chapter 2_Breeds of Domestic Ducks -- Chapter 3_Duck Genetics and Breeding-Chapter 4_Anatomy and Physiology of Ducks -- Chapter 5_Nomadic (Transhumant) Duck Rearing -- Chapter 6_Integrated Duck Farming -- Chapter 7_Intensive Duck Rearing -- Chapter 8_Feeding and Nutrient Requirements of Ducks -- Chapter 9_Incubation and Hatching of Duck Eggs -- Chapter 10_Nutritive Value of Duck Meat and Eggs -- Chapter 11_Duck Slaughter Processing, Meat Quality Measurements and Value Addition -- Chapter 12_Duck Meat and Egg Products in Different Cuisines -- Chapter 13_Value Addition of Feather and Down -- Chapter 14_Duck Diseases & Disease Management -- Chapter 15_Duck Genomics and Biotechnology -- Chapter 16_ Duck Farming: Constraints and Recommendations.
    Abstract: This book provides comprehensive insights into the field of duck production and management. It presents a complete overview of different aspects of duck production with particular emphasis on rearing systems. The book reviews current knowledge on the anatomy, physiology, genetics, breeding, nutrition, incubation, and hatching practices of ducks. It further discusses the common diseases of duck, their treatment regime, and prevention strategies. The book additionally examines all aspects of the global duck industry, the constraints, and the recommendations. It also explores nutrient requirements and feed evaluation for duck and evaluates nutrition's influence on the gut microbiome. Towards the end, the book presents the latest genomic applications, including high throughput sequencing and various bioinformatics tools in duck production. This book serves as an essential resource for duck industry practitioners, researchers, and students.
    Type of Medium: Online Resource
    Pages: XVI, 657 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811661006
    DDC: 636
    Language: English
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    Keywords: Bioremediation. ; Plant biotechnology. ; Nanotechnology. ; Biomaterials. ; Nanobiotechnology. ; Environmental Biotechnology. ; Plant Biotechnology. ; Nanotechnology. ; Biomaterials. ; Nanobiotechnology.
    Description / Table of Contents: Preface -- Facile Synthesis of Silver Nanocoated Cotton Fabrics from Medicinal Plant Leaf Extract Against Nosocomial Infection -- Biomimetic Synthesis of Silver Nanoparticles from Medicinal Plants and Its Impact on A431 Epidermoid Cancer Cell Lines -- Role of Nanomaterials in Rheumatoid Arthritis -- Nanoparticles in Food Science and Packaging -- Application of Nanomaterials in Heavy Metal Remediation and Pollution Control -- Comparison of Biophysical Characters and Insecticidal Potential of Silver Nanoparticles Assisted by Citrus medica, Tagetes lemmonii and Tarenna asiatica Extracts -- Review on Recent Advanced Synthetic Methods of Nanomaterials -- Heterostructured Nanomaterials for Supercapacitor Applications -- Rare Earthmetals, Transition Metals, Doped Metal Oxide Nanoparticles -- Biogenic Metallic Nanoparticles for Diagnosis and Treatment of Lung Cancer -- Applicability of Nanomaterials in Microbial Fuel Cells as Cathode Catalysts -- Pollutant Removal from Coffee Industry Wastewater Using Polymer-Based Nano-Adsorbent as a Novel and Promising New Generation Adsorbent -- A Review on the Application of Biogenic Metal Oxide Nanomaterials in Textile Wastewater Treatment -- Advanced Two-Dimensional Transition Metal Carbides and Nitrides (MXenes) for Wastewater Treatment Applications -- Carbon Nanomaterials for the Remediation of Industrial Effluents -- Impact of Nanomaterials on Solid Waste Management -- Agent Nanoencapsulation -- Potential Applications of Nanomaterials in Agronomy -- Application of Emerging Nanomaterials in Animal Origin Products and Packaging from Indonesia -- Bibliography -- Index.
    Abstract: Over the past decade the world has seen the rise of the fascinating and diverse field currently recognized as nanotechnology. This book covers a broad spectrum of topics within nanotechnology, including synthesis techniques, various innovative characterization techniques, growth mechanisms of nanomaterials, the physics and chemistry of nanomaterials, diverse functionalization methods, and the various applications of nanomaterials in biology, therapeutics, energy, food science, and environmental science. It also discusses applications of nanostructured materials, integrative applications such as nano- and micro-electronic sensor devices, as well as agricultural and environmental remediation applications. The book also includes a discussion of advances in functionalized nanomaterials (0D, 1D, 2D and 3D) and covers the early stages of the development of functionalized nanostructures, considering the future for 2D nanomaterials and 3D objects. Additionally, it includes a chapter on nanomaterial research development that highlights work on the life-cycle analysis of nanostructured materials and toxicity aspects. This book proves useful for researchers and professionals working in the field of nanomaterials and green technology, as well as in the field of nanotechnology. It should be useful to students and specialized researchers in a number of disciplines ranging from biology, chemistry, and materials science to engineering and manufacturing in both academia and industry.
    Type of Medium: Online Resource
    Pages: XXI, 785 p. 202 illus., 186 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030803711
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 628.5
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Molecular probes. ; Biomedical engineering. ; Nanobiotechnology. ; Nanotechnology. ; Biological Sensors and Probes. ; Biomedical Engineering and Bioengineering. ; Nanobiotechnology. ; Nanotechnology.
    Description / Table of Contents: Chapter 1: Sensor-assisted Next-generation Diagnostics: Emerging Concepts, Biomarkers, Technologies, and Challenges -- Chapter 2: Carbon electrodes as emerging platforms for miniaturization of electrochemical biosensors -- Chapter 3: Ion track-based nanofluidic biosensors -- Chapter 4: Clinical Biosensors: Considerations and Development Process -- Chapter 5: Development and Implementation of Portable Biosensors in Microfluidic Point-of-Care Devices for Pathogen Detection -- Chapter 6: Recent trends in clinical diagnosis for viral disease detection based on miniaturized biosensors -- Chapter 7: Continuous glucose monitoring for diabetes management based on miniaturized biosensors -- Chapter 8: Transforming Healthcare Technologies With Wearable, Implantable, And Ingestible Biosensors and Digital Health -- Chapter 9: Multiplexed biosensors for efficient diagnosis of the clinical conditions towards health management -- Chapter 10: Biocompatible sensors are revolutionizing healthcare technologies -- Chapter 11: Onsite quality controls for food safety based on miniaturized biosensing -- Chapter 12: Gold nanoparticle-based colorimetric sensing of metal toxins -- Chapter 13: Miniaturized sensing strategies for next-generation nitrogen monitoring -- Chapter 14: Recent Trends Towards the Development of Biosensors for Biosafety and Biohazards -- Chapter 15: Commercial aspects and market pull of biosensors in diagnostic industries.
    Abstract: This book presents tools and techniques for the development of miniature biosensors and their applications. The initial chapters discuss the advancements in the development of the transduction techniques, including optical, electrochemical, and piezoelectric, which are used for miniaturized biosensors. The book also reviews several technologies, such as nanotechnology, nanobiotechnology, immune-technology, DNA-technology, micro-manufacturing technology, electronic-circuit technology to increase the miniaturization and sensitivity of the biosensor platform. Subsequently, the chapters illustrate the applications of miniaturized biosensing systems in point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery, forensics, and biomedical research. Towards the end, the book discusses the advanced applications of biosensors in water quality monitoring, especially on-line detection systems and on-site detection of pesticides, heavy metals and bacteria in water. This book is an invaluable source for scientists working in biochemical engineering, bioengineering, and biomedical engineering in academia and industry.
    Type of Medium: Online Resource
    Pages: XII, 368 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811698972
    DDC: 571.6028
    Language: English
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    Keywords: Microbial ecology. ; Bacteria. ; Microbiology. ; Plant diseases. ; Bioinformatics. ; Microbial Ecology. ; Bacteria. ; Microbiology. ; Plant Pathology. ; Computational and Systems Biology.
    Description / Table of Contents: Chapter 1. Rhizosphere Metagenomics – Methods and Challenges -- Chapter 2. Metagenomic Approach in Relation to Plant-Microbe and Microbe-Microbe Interactions -- Chapter 3. Metagenomics and metatranscriptomics approaches in understanding and discovering novel molecules in rhizosphere environment -- Chapter 4. "Omics” approaches for understanding soil suppressiveness in agriculture -- Chapter 5. Rhizosphere dynamics: an OMICS perspective -- Chapter 6. Transcriptomics analyses and the relationship between plant and plant growth-promoting rhizobacteria (PGPR) -- Chapter 7. Proteomics for understanding the interaction between plant and rhizospheric microflora -- Chapter 8. A proteomics perspective for understanding rhizosphere biology at higher altitudes -- Chapter 9. Structural and functional rhizospheric microbial diversity analysis by cutting edge biotechnological tools -- Chapter 10. Rhizosphere Fingerprints: Novel Biomolecules via Meta-Omics Technology -- Chapter 11. Rhizosphere virology and plant health -- Chapter 12. Long sequencing tools for rhizosphere study -- Chapter 13. Rhizoengineering: A strategy to enhance soil and crop productivity -- Chapter 14. Endospheric microbiome assisted alteration in the metabolomic profiling of host towards abiotic stress mitigation. .
    Abstract: This book presents a timely review of the latest advances in rhizosphere biology, which have been facilitated by the application of omics tools. It includes chapters on the use of various omics tools in rhizosphere biology, focusing on understanding plant and soil microbe interactions. The role of proteomics and metagenomics in research on symbiotic association is also discussed in detail. The book also includes chapters on the use of omics tools for the isolation of functional biomolecules from rhizospheric microorganisms. The book’s respective sections describe and provide detailed information on important omics tools, such as genomics, transcriptomics, proteomics, metabolomics and meta-epigenomics. In turn, the book promotes and describes the combined use of plant biology, microbial ecology, and soil sciences to design new research strategies and innovative methods in soil biology. Lastly, it highlights the considerable potential of the rhizosphere in terms of crop productivity, bioremediation, ecological engineering, plant nutrition and health, as well as plant adaptation to stress conditions. This book offers both a practical guide and reference source for all scientists working in soil biology, plant pathology, etc. It will also benefit students studying soil microbiology, and researchers studying rhizosphere structure. .
    Type of Medium: Online Resource
    Pages: XIII, 279 p. 24 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811608896
    Series Statement: Rhizosphere Biology,
    DDC: 579.17
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Biomathematics. ; Biochemistry. ; Biology Technique. ; Biophysics. ; Computational and Systems Biology. ; Mathematical and Computational Biology. ; Bioinformatics. ; Biochemistry. ; Biophysical Methods.
    Description / Table of Contents: 1. Introduction to graph theory -- 2. Biological networks -- 3. Network inference for drug discovery- 4. Introduction to differential and integral calculus -- 5. Modelling chemical reactions -- 6. Reaction-diffusion systems -- 7. Linear algebra background -- 8. Regression -- 9. Cardiac electrophysiology -- .
    Abstract: This introductory guide provides a thorough explanation of the mathematics and algorithms used in standard data analysis techniques within systems biology, biochemistry, and biophysics. Each part of the book covers the mathematical background and practical applications of a given technique. Readers will gain an understanding of the mathematical and algorithmic steps needed to use these software tools appropriately and effectively, as well how to assess their specific circumstance and choose the optimal method and technology. Ideal for students planning for a career in research, early-career researchers, and established scientists undertaking interdiscplinary research. .
    Type of Medium: Online Resource
    Pages: X, 264 p. 40 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031365669
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 570.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cytology. ; Regenerative medicine. ; Medicine Research. ; Biology Research. ; Bioinformatics. ; Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Research. ; Bioinformatics.
    Description / Table of Contents: Brain Tissue Oxygen and BOLD fMRI Under Different Levels Of Neuronal Activity -- Cerebral Microcirculation and Oxygenation Modulation by Transcranial Alternating Current Stimulation in Awake and Anesthetized Mice -- The Effect of Hypercapnia on Cortical Metabolic Rate and Mitochondrial Redox Status -- Relationship Between Left-Right Dominancy of Prefrontal Cortex Activity and Heart Rate During Rest and Task Periods: An fNIRS Study -- Relationship Between Cognitive Function, Oral Conditions and Systemic Metabolic Function in the Elderly -- Pro-survival Phenotype of HIF-1α: Neuroprotection through Inflammatory Mechanisms -- Infradian Rhythms in Cerebrovascular Oxygenation and Blood Volume in Humans at Rest: A 5-year Study -- Mechanisms of Photostimulation of Brain’s Waste Disposal System: the Role of Singlet Oxygen -- Changes of Arterial and Venous Cerebral Blood Flow Correlation in Moderate-to-Severe Traumatic Brain Injury: A CT Perfusion Study -- Cerebral Net Water Uptake in Posttraumatic Cerebral Ischemia -- Brainstem Damage Underlies Changes in Hypoxic Ventilatory Response following Cardiac Arrest and Resuscitation in Rats -- Differences Between Good, Moderate and Poor Performers of a Verbal Fluency Task under Blue Light Exposure: An SPA-fNIRS Study -- Sex-specific and Dose-dependent Effects of Drag-Reducing Polymers on Microcirculation and Tissue Oxygenation in Rats after Traumatic Brain Injury -- Accuracy of Tissue Oxygen Saturation Measurements of a Textile-based NIRS Sensor -- Understanding the Role of Caveolae in Oxygen Buffering: The Effect of Membrane Curvature -- The Significance of Lipids for the Absorption and Release of Oxygen in Biological Organisms -- How Skin Color Depends on Tissue Oxygenation -- Tissue Concentration Analysis of Sulfur, Calcium and Oxygen in novel Skin Primo Nodes After Acupuncture -- Primo Vessels Inside Lymphatic Vessels are Absent in an ALS Mouse Model -- The Impact of Heterogeneous Cell Density in Hypoxic Tumors Treated with Radiotherapy -- A Critical Analysis of Possible Mechanisms for the Oxygen Effect in Radiation Therapy with FLASH -- Hyperhydration of Cancers: A Characteristic Biophysical Trait Strongly Increasing O2, CO2, Glucose and Lactate Diffusivities, and Improving Thermophysical Properties of Solid Malignancies -- No Difference in Muscle Basal Oxygenation in a Bedridden Population pre and Post Rehabilitation -- Relationship between Muscle Deoxygenation and Cardiac Output in Subjects without Attenuation of Deoxygenation Hemoglobin Concentration near the end of Ramp Cycling Exercise: A Longitudinal Study -- Image Reconstruction Using Deep Learning for Near-Infrared Optical Tomography: Generalization Assessment -- Neonatal Brain Temperature Monitoring Based on Broadband Near-Infrared Spectroscopy -- Time Domain Near-Infrared Optical Tomography Utilizing Full Temporal Data: A Simulation Study -- BIAN: A Multilayer Microfluidic-Based Tissue-Mimicking Phantom for Near-Infrared Imaging -- Do Vascular and Extracellular Measurements Consistently Reflect Intracellular pO2? Observation of Tissue Oxygenation Changes using Remote Photoplesysmography with a Smartphone -- Neurovascular, Metabolic, and Glymphatic Dynamics of the Brain Measured with fNIRS -- Imaging Cerebral Blood Vessels Using Near-Infrared Optical Tomography: A Simulation Study -- Reduced Cerebrovascular Oxygenation in Individuals with Post-Acute COVID-19 Syndrome (PACS) (“Long COVID”) -- Insufficient Oxygen Supplementation During Cardiopulmonary Resuscitation Leads to Unfavorable Biological Response While Hyperoxygenation Contributes to Metabolic Compensation -- Block of the Angiotensin Pathways Affects Flow-Volume Spirometry in Patients With SARS-CoV-2 Infection -- A Prospective Observational Pilot Study on the Effects of the Activity-based Stress Release Program on the Mental State and Autonomic Nervous System in Psychiatric patients. .
    Abstract: This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 49th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2022). Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.
    Type of Medium: Online Resource
    Pages: XIX, 240 p. 91 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031420030
    Series Statement: Advances in Experimental Medicine and Biology, 1438
    DDC: 571.6
    Language: English
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    Keywords: Agricultural biotechnology. ; Agronomy. ; Agricultural genome mapping. ; Nanotechnology. ; Agriculture. ; Agricultural Biotechnology. ; Agronomy. ; Agricultural Genetics. ; Nanotechnology. ; Agriculture.
    Description / Table of Contents: Chapter 1. An introduction to rice diseases -- Chapter 2. Bacterial diseases of rice -- Chapter 3. Viral diseases of rice -- Chapter 4. Etiology, epidemiology, and management of maize diseases -- Chapter 5. Viral diseases of maize -- Chapter 6. Barley diseases: Introduction etiology, epidemiology, and their management -- Chapter 7. Identification of new susceptibility gene and its role in plant immunity -- Chapter 8. Breeding strategies for developing disease-resistant wheat: present, past, and future -- Chapter 9. Potential breeding strategies for developing disease-resistant barley: progress, challenges, and applications -- Chapter 10. Economic and Eco-friendly alternatives for the efficient and safe management of wheat diseases -- Chapter 11. Resistance gene identification, cloning, and characterization in plants -- Chapter 12. The role of genetic, genomic, and breeding approaches in the fight against fungal diseases in wheat -- Chapter 13. Disease Resistance genes identification, cloning, and characterization in plants -- Chapter 14. Utilization of Biosensors in the Identification of Bacterial Diseases in Maize -- Chapter 15. Nanomaterials for integrated crop disease managemenT -- Chapter 16. Metallic Nanoparticles and Nano-based bioactive formulations as Nano fungicides for Sustainable Disease Management in Cereals -- Chapter 17. Applications of nano-biotechnological Approaches in Diagnosis and Protection of Wheat Diseases -- Chapter 18. Nanomaterials for the Reduction of Mycotoxins in Cereals.
    Abstract: New ways to improve cereal crops against fungal, bacterial, and viral diseases are covered in this book that was put together by a group of experts. These include genetics, genome editing systems, and nano-biotechnological tools. Cereal crops are mainly the world's leading food crops and feed a large share of the world population. However, external factors, such as pathogens, have often threatened their productivity. Like wheat, rice, maize, oats, barley, millet and storage, etiology, epidemiology, and diseases in cereal crop management. In addition, the importance of crop genetics and genomics in combating pathogens has been discussed. This book offers up-to-date information on new methods, such as the potential of the genome editing system for crop improvement, in particular the CRISPR-Cas system. The current volume also talks about identification, plant breeding, genome editing, and nanotechnology tools that can be used to fight disease in cereal crops. This book is good for students, teachers, and researchers who study biotic stress in cereals, as well as scientists who study nanotechnology, disease resistance, pathogen biology, genome editing, agriculture sciences, and future biotechnology.
    Type of Medium: Online Resource
    Pages: XII, 406 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811931208
    DDC: 630
    Language: English
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    Keywords: Agriculture. ; Nanotechnology. ; Food science. ; Forestry. ; Agriculture. ; Nanotechnology. ; Food Science. ; Forestry.
    Description / Table of Contents: Recent trends, prospects, and challenges of nanobiosensors in agriculture -- Nanostructured platforms integrated to biosensors: Recent applications in agriculture. Advances in nanotechnology for bio-sensing in agriculture and food -- Nanomaterial based gas sensor for agriculture sector -- Volatile organic compounds (VOCs) sensors for stress management in crops -- Current trends of plasmonic nanosensors use in agriculture -- Relevance of biosensor in climate smart organic agriculture and their role in environmental sustainability: What has been done and what we need to do? -- New trends in biosensors for pesticide detection -- Application of biosensor for the identification of various pathogens and pests mitigating against the agricultural production: recent advances -- Gold nanoparticles-based point-of-care colorimetric diagnostic for plant diseases -- Advancements in biosensors for fungal pathogen detection in plants -- Journey of Agricultural sensors – From conventional to ultra-modern -- PART II: Biosensors in food science, Advances in biosensors based on electrospun micro/nanomaterials for food quality control and safety -- Current trend of electrochemical sensing for mytoxins -- Biosensor for fruit quality monitoring -- Lateral flow assays for food authentication -- Nanobiosensors in agriculture and foods: a scientometric review -- PART III: Biosensors in animal and fishery Sciences, Biosensors: Modern tools for disease diagnosis and animal health monitoring -- Nano-biosensing devices detecting biomarkers of communicable and non-communicable diseases of animals -- Recent advances in biosensor development for poultry industry -- Smart aquaculture: Integration of sensors, biosensors, and artificial intelligence -- Biosensor as potential tool for on-site detection of insect pathogens.
    Abstract: This book reviews the application of nanosensors in food and agriculture. Nanotechnology has the potential to become transformative technology that will impact almost all sectors. Tools like nanosensors, which detect specific molecular interactions, can be used for on-site, in-situ and online measurements of various parameters in clinical diagnostics, environmental and food monitoring, and quality control. Due to their unprecedented performance and sensitivity, nanobiosensors are gaining importance in precision farming. The book examines the use of nanobiosensors in the monitoring of food additives, toxins and mycotoxins, microbial contamination, food allergens, nutritional constituents, pesticides, environmental parameters, plant diseases and genetically modified organisms. It also discusses the role of biosensors in increasing crop productivity in sustainable agriculture, and nanosensor-based smart delivery systems to optimize the use of natural resources such as water, nutrients and agrochemicals in precision farming.
    Type of Medium: Online Resource
    Pages: XV, 493 p. 83 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030661656
    Series Statement: Concepts and Strategies in Plant Sciences,
    DDC: 630
    Language: English
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    Keywords: Invertebrates. ; Animal culture. ; Physiology. ; Biodiversity. ; Freshwater ecology. ; Marine ecology. ; Bioinformatics. ; Invertebrate Zoology. ; Animal Science. ; Animal Physiology. ; Biodiversity. ; Freshwater and Marine Ecology. ; Computational and Systems Biology.
    Description / Table of Contents: Chapter 1. An Introduction to the Dytiscidae: Their Diversity, Historical Importance, Cultural Significance, and Other Musings -- Chapter 2. Larval Chaetotaxy of World Dytiscidae (Coleoptera: Adephaga) and Implications for the Study of Hydradephaga -- Chapter 3. The Phylogeny and Classification of Predaceous Diving Beetles (Coleoptera: Dytiscidae) -- Chapter 4. Predaceous Diving Beetle Sexual Systems -- Chapter 5. Morphology, Anatomy, and Physiological Aspects of Dytiscids -- Chapter 6. Chemical Ecology and Biochemistry of Dytiscidae -- Chapter 7. Community Patterns in Dytiscids -- Chapter 8. Predator-Prey Ecology of Dytiscids -- Chapter 9. The Unique Australian Subterranean Dytiscidae: Diversity, Biology, and Evolution -- Chapter 10. Habitats Supporting Dytiscid Life -- Chapter 11. Dispersal in Dytiscidae -- Chapter 12. The Conservation of Predaceous Diving Beetles: Knowns, Unknowns and Anecdotes.
    Abstract: The 2nd edition of this comprehensive book provides one of the most complete overviews of the aquatic beetles in the family Dytiscidae, also known as predaceous diving beetles. Dytiscids constitute one of the largest families of freshwater insects with approximately 4,650 named species that come in a variety of sizes, colors, and habitat affinities. Although dytiscid adults and larvae are ubiquitous throughout a variety of aquatic habitats, and are important predators on other aquatic invertebrates and vertebrates, there are no compilations that have focused on summarizing the knowledge on aspects of their ecology, systematics, and biology. Chapters in this book summarize hitherto scattered topics, including their anatomy and habitats, chemical and community ecology, phylogenies and larval morphology including chaetotaxy, sexual systems, predation, dispersal, conservation, and cultural and historical aspects. The 2nd edition offers updates on the newest scientific findings on dytiscids and also includes a new chapter on the subterranean fauna from Australia. The information in this new edition is potentially beneficial to anyone working in aquatic systems where dytiscids are an important part of the food web. Moreover, readers will gain a greater appreciation of dytiscids as model organisms for investigations of fundamental principles derived from ecological and evolutionary theory. Contributed chapters are by authors who are actively engaged in studying dytiscids, and each chapter provides color photos and future directions for research.
    Type of Medium: Online Resource
    Pages: XII, 573 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031012457
    DDC: 592
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Nanotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Genetics. ; Biotechnology. ; Nanotechnology. ; Microsystems and MEMS. ; Genetics and Genomics. ; Chemical Bioengineering.
    Description / Table of Contents: Introduction: DNA basics (a primer on DNA) -- Hiding and storing messages and data in DNA -- DNA as a nanoscale building material -- DNA machines and nanobots -- DNA-based nanoelectronics -- Concluding remarks.
    Abstract: This is the first book portraying to a wide readership many fields of DNA in the world of materials altogether in a single volume. The book provides underlying concepts and state-of-art developments in the emerging fields of DNA electronics, structural DNA nanotechnology, DNA computing and DNA data storage, DNA machines and nanorobots. Future possibilities of innovative DNA-based technologies, such as DNA cryptography, DNA identity tags, DNA nanostructures in biosensing and nanomedicine, as well as DNA-based nanoelectronics are all covered, too. This book is valuable for university students studying engineering and technology; biotech, nanotech, and medical device R&D managers, practitioners and investors; and IP analysts who would like to extend their background in advanced DNA technologies. It is nicely illustrated, which makes it very readable, and it conveys science and principles in a lively language to appeal to a broad audience, from professionals and academics to students and lay readers. Advance Praise for DNA Beyond Genes: “Most students of DNA, and lay readers as well, are interested in the absolutely essential role it plays in biology. However, the properties which make DNA the carrier of genetic information also make it an extraordinary material that can be used as the backbone for a wide variety of nanoengineering applications – these range from information storage and computation to molecular machines and devices to artfully designed logos and symbols. The perfect self-recognition of DNA sequences makes it an ideal building block to synthesize more and more elaborate constructions and imaginative scientists have probably only just scratched the surface of what can eventually be created. Here for the first time in this wonderful book Vadim Demidov explores the full range of the non-biological applications of DNA.” Charles R. Cantor Professor Emeritus of Biomedical Engineering, Boston University Member of the USA National Academy of Sciences.
    Type of Medium: Online Resource
    Pages: XX, 107 p. 66 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030364342
    DDC: 660.6
    Language: English
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    Keywords: Biotechnology. ; Nanotechnology. ; Regenerative medicine. ; Immunology. ; Biotechnology. ; Nanotechnology. ; Regenerative Medicine and Tissue Engineering. ; Immunology.
    Description / Table of Contents: Chapter 1. Nanomaterials, classifications, and properties -- Chapter 2. Engineering nanomaterials for bio-interfacing -- Chapter 3. Biomaterials and surface modification strategies -- Chapter 4. Nano materials as a nanotheronostic agent -- Chapter 5. Nanobiomaterials in biomedicine: Designing strategies and critical concepts -- Chapter 6. Phytofabricated nanodelivery systems: Engineering principles and applications -- Chapter 7. Nanobiosensors based diagnostics system: Transducers and surface materials -- Chapter 8. Nanobiomaterials and nanocomposites in clinical diagnostics -- Chapter 9. Tissue Engineering and Regenerative Medicines based on nanobiomaterials -- Chapter 10. Prospects and advantages of microfluidics utilizing various nanobiomaterials -- Chapter 11. Electrochemical nanoengineered sensors in infectious disease diagnosis -- Chapter 12. Multiplexing utilizing various nanobiomaterials -- Chapter 13. Future perspects of nanobiomaterials in human health care -- Chapter 14. Commercial aspects of nanobiomaterials: Short-coming and future aspects.
    Abstract: This book comprehensively documents the application of Nanobiomaterials in the field of bio-medicine and diagnostics technologies by involving classical concepts/examples. Nanobiotechnology is an emerging area which encompasses all the facets of research of nano and biomaterials with their interaction with biological systems. The book summarises design and development of various nanobiomaterials and their composites for diagnostics and therapeutic applications. It skilfully reviews the utilization of the nanomaterials alone or in combination with other bio-molecules as a contrast enhancer in in-vivo imaging, Nano-Theranostics, drug delivery, and sensing transducer matrix. It also discusses the current research on designing of the new Nanobiomaterials and their implementation in numerous fields including bio-medicine and diagnostics. Finally, it summarizes the future prospects and the commercial viability of Nanobiomaterials in the human health care.
    Type of Medium: Online Resource
    Pages: XII, 294 p. 108 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813298408
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Proteins . ; Proteins. ; Enzymology. ; Medical genetics. ; Bioinformatics. ; Protein Biochemistry. ; Proteins. ; Enzymology. ; Medical Genetics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Protein Purification, Estimation, Storage and Effect on Structure, Function and Dynamics -- Chapter 2. Experimental and Computational Methods to Determine Protein Structure and Stability -- Chapter 3. Wet-Lab Approaches to Determine Three-Dimensional Structures of Proteins -- Chapter 4. Use of Group Specific Reagents in Active Site Functional Group Elucidation I: Cys, Ser, Tyr and Trp Residues -- Chapter 5. Use of Group Specific Reagents in Active Site Functional Group Elucidation II: Asp, Glu, Arg, Lys and His residues -- Chapter 6. Protein-Protein Interactions Modeling: From Dry to Wet Lab -- Chapter 7. Thermodynamics of Protein-Ligand Binding -- Chapter 8. SynergisticEffects of Hydration Sites in Protein Stability: A Theoretical Water Thermodynamics Approach -- Chapter 9. Molecular Dynamics Simulation: Methods and Application -- Chapter 10. Protein Folding, Dynamics and Aggregation at Single Molecule Resolution -- Chapter 11. Protein Misfolding and Neurodegenerative Diseases -- Chapter 12. Management of Insulin Through Co-Solute Engineering: A Therapeutic Approach -- Chapter 13. Structural and Functional Aspects of Muscarinic Receptors in Correlation with Anticholinergic Drugs -- Chapter 14. Dopamine Β Hydroxylase: An Enzyme with Therapeutic Potential to Combat Neural and Cardiovascular Diseases -- Chapter 15. Molecular Motors: Subdomain Dynamics and Mechanochemistry -- Chapter 16. Structural and Functional Dynamics of Lysosomal Cysteine Proteases with Particular Reference to Cathepsin B and Cathepsin H -- Chapter 17. An Insight into the Importance of Ferritins in the Physiology of Mycobacterium tuberculosis: Unique Structural and Functional Properties.
    Abstract: This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances. Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecular motors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins. Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.
    Type of Medium: Online Resource
    Pages: XII, 452 p. 71 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811555305
    DDC: 572.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Artificial intelligence. ; Bioinformatics. ; Biomedical Research. ; Artificial Intelligence. ; Bioinformatics.
    Description / Table of Contents: 1-Dimensional Convolution Neural Network Classification Technique for Gene Expression Data -- Classification of Sequences with Deep Artificial Neural Networks: Representation and Architectural Issues -- A Deep Learning Model for MicroRNA-Target Binding -- Recurrent Neural Networks Architectures for Accidental Fall Detection on Wearable Embedded Devices -- Medical Image Retrieval System using Deep Learning Techniques -- Medical Image Fusion using Deep Learning -- Deep Learning for Histopathological Image Analysis -- Innovative Deep Learning Approach for Biomedical Data Instantiation and Visualization -- Convolutional Neural Networks in Advanced Biomedical Imaging Applications -- Deep Learning for Lung Disease Detection from Chest X-Rays Images -- Deep Learning in Multi-Omics Data Integration in Cancer Diagnostic -- Using Deep Learning with Canadian Primary Care Data for Disease Diagnosis -- Brain Tumor Segmentation and Surveillance with Deep Artificial Neural Networks.
    Abstract: This book is the first overview on Deep Learning (DL) for biomedical data analysis. It surveys the most recent techniques and approaches in this field, with both a broad coverage and enough depth to be of practical use to working professionals. This book offers enough fundamental and technical information on these techniques, approaches and the related problems without overcrowding the reader's head. It presents the results of the latest investigations in the field of DL for biomedical data analysis. The techniques and approaches presented in this book deal with the most important and/or the newest topics encountered in this field. They combine fundamental theory of Artificial Intelligence (AI), Machine Learning (ML) and DL with practical applications in Biology and Medicine. Certainly, the list of topics covered in this book is not exhaustive but these topics will shed light on the implications of the presented techniques and approaches on other topics in biomedical data analysis. The book finds a balance between theoretical and practical coverage of a wide range of issues in the field of biomedical data analysis, thanks to DL. The few published books on DL for biomedical data analysis either focus on specific topics or lack technical depth. The chapters presented in this book were selected for quality and relevance. The book also presents experiments that provide qualitative and quantitative overviews in the field of biomedical data analysis. The reader will require some familiarity with AI, ML and DL and will learn about techniques and approaches that deal with the most important and/or the newest topics encountered in the field of DL for biomedical data analysis. He/she will discover both the fundamentals behind DL techniques and approaches, and their applications on biomedical data. This book can also serve as a reference book for graduate courses in Bioinformatics, AI, ML and DL. The book aims not only at professional researchers and practitioners but also graduate students, senior undergraduate students and young researchers. This book will certainly show the way to new techniques and approaches to make new discoveries.
    Type of Medium: Online Resource
    Pages: VI, 359 p. 130 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030716769
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Cytology. ; Bioinformatics. ; Biology Technique. ; Biotechnology. ; Cell Biology. ; Computational and Systems Biology. ; Biological Techniques.
    Description / Table of Contents: Workflows and Components of Bioimage Analysis -- Measurements of Intensity Dynamics at the Periphery of the Nucleus -- 3D Quantitative Colocalisation Analysis -- The NEMO Dots Assembly: Single-Particle Tracking and Analysis -- Introduction to MATLAB: Image Analysis & Brownian Motion -- Resolving the process of Clathrin Mediated Endocytosis Using Correlative Light & Electron Microscopy (CLEM).
    Abstract: This Open Access textbook provides students and researchers in the life sciences with essential practical information on how to quantitatively analyze data images. It refrains from focusing on theory, and instead uses practical examples and step-by step protocols to familiarize readers with the most commonly used image processing and analysis platforms such as ImageJ, MatLab and Python. Besides gaining knowhow on algorithm usage, readers will learn how to create an analysis pipeline by scripting language; these skills are important in order to document reproducible image analysis workflows. The textbook is chiefly intended for advanced undergraduates in the life sciences and biomedicine without a theoretical background in data analysis, as well as for postdocs, staff scientists and faculty members who need to perform regular quantitative analyses of microscopy images.
    Type of Medium: Online Resource
    Pages: X, 170 p. 69 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030223861
    Series Statement: Learning Materials in Biosciences,
    DDC: 660.6
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agriculture. ; Environmental monitoring. ; Computer-aided engineering. ; Bioinformatics. ; Computer simulation. ; Agriculture. ; Environmental Monitoring. ; Computer-Aided Engineering (CAD, CAE) and Design. ; Computational and Systems Biology. ; Computer Modelling.
    Description / Table of Contents: Section I - MODELLING IN WEED SCIENCE -- Chapter 1 - Mathematical models -- Chapter 2 - Decision Support Systems in Weed Science -- Chapter 3 - Optimization in DSS -- Section II - BIO-ECOLOGICAL MODELS -- Chapter 4 - Population-based models -- Chapter 5 - Weed germination and dormancy models -- Chapter 6 - Field Emergence models -- Chapter 7 - Interference/Competition models -- Chapter 8 - Herbicide resistance modelling -- Section III - ENVIRONMENTAL RISK MODELLING -- Chapter 9 - Theory and practice for environmental risk assessment of weed management systems -- Chapter 10 - Environmental risk indicators for weed management assessment: a case study of ecotoxicity risk using fuzzy logic -- Chapter 11 - DRASTIC GIS-based models: assessing the vulnerability of groundwater resources -- Section IV - WEED MANAGEMENT DECISION SUPPORT SYSTEMS: STUDY CASES -- Chapter 12 - FLORSYS model: How to use a virtual field to evaluate and design IWM strategies at different spatial and temporal scales -- Chapter 13 - Ryegrass Integrated Management (RIM)-based DSS -- Chapter 14 - CPOweeds: DSS for multispecies weed control in cereals crops -- Chapter 15 - AVENA-NET/LOLIUM-NET: DSS for Avena sterilis and Lolium rigidum control in cereal crops -- Chapter 16 - AVESUD: DSS for Avena fatua control in winter cereal crop rotations -- Chapter 17 - DSS Perspectives, Challenges and Future work.
    Abstract: Weed management Decision Support Systems (DSS) are increasingly important computer-based tools for modern agriculture. Nowadays, extensive agriculture has become highly dependent on external inputs and both economic costs, as well the negative environmental impact of agricultural activities, demands knowledge-based technology for the optimization and protection of non-renewable resources. In this context, weed management strategies should aim to maximize economic profit by preserving and enhancing agricultural systems. Although previous contributions focusing on weed biology and weed management provide valuable insight on many aspects of weed species ecology and practical guides for weed control, no attempts have been made to highlight the forthcoming importance of DSS in weed management. This book is a first attempt to integrate 'concepts and practice' providing a novel guide to the state-of-art of DSS and the future prospects which hopefully would be of interest to higher-level students, academics and professionals in related areas.
    Type of Medium: Online Resource
    Pages: XII, 342 p. 86 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030444020
    DDC: 630
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Evolution (Biology). ; Bioinformatics. ; Evolutionary Biology. ; Computational and Systems Biology.
    Description / Table of Contents: Part I Problems -- 1 The Unix Command Line -- 1.1 Getting Started -- 1.2 Files, Directories, and Programs.-1.3 Scripts -- 2 Optimal Alignment -- 2.1 Keeping Score -- 2.2 Construction -- 2.3 Application -- 3 Exact Matching -- 3.1 Keyword Trees -- 3.2 Suffix Trees -- 3.3 Suffix Arrays -- 3.4 Text Compression -- 4 Fast Alignment -- 4.1 Global -- 4.2 Local -- 4.3 Glocal -- 4.4 Assembly -- 4.5 Multiple Sequences -- 5 Evolution Between Species: Phylogeny -- 5.1 Trees of Life -- 5.2 Rooted Trees -- 5.3 Unrooted Trees -- 6 Evolution within Populations -- 6.1 Descent from One or Two Parents -- 6.2 The Coalescent -- 7 Interrogating and Storing Data -- 7.1 Statistics -- 7.2 Relational Databases -- Part II Answers. -- 1 The Unix Command Line -- 1.1 Getting Started -- 1.2 Files, Directories, and Programs -- 1.3 Scripts -- 2 Optimal Alignment -- 2.1 Keeping Score -- 2.2 Construction -- 2.3 Application -- 3 Exact Matching -- 3.1 Keyword Trees -- 3.2 Suffix Trees -- 3.3 Suffix Arrays -- 3.4 Text Compression -- 4 Fast Alignment -- 4.1 Global -- 4.2 Local -- 4.3 Glocal -- 4.4 Assembly -- 4.5 Multiple Sequences -- 5 Evolution Between Species: Phylogeny -- 5.1 Trees of Life -- 5.2 Rooted Trees -- 5.3 Unrooted Trees -- 6 Evolution within Populations -- 6.1 Descent from One or Two Parents -- 6.2 The Coalescent -- 7 Interrogating and Storing Data -- 7.1 Statistics -- 7.2 Relational Databases -- A. Unix Guide -- B. Programs -- B.1 Own -- B.2 Biobox -- B.3 Third-Party -- References -- Index.
    Abstract: This self-contained textbook covers fundamental aspects of sequence analysis with special emphasis on evolutionary biology, including sequence alignment, exact matching, phylogeny reconstruction, and coalescent simulation. It addresses these topics through a series of over 800 computer problems, ranging from elementary to research level, to enable learning by doing. Students solve the problems in the same computational environment used for decades in science – the Unix command line. This is available on all four major operating systems for PCs: Windows, macOS, chromeOS, and Linux. To learn using this powerful system, students analyze sample sequence data by applying generic tools, bioinformatics software, and over 50 programs specifically written for this course and available via GitHub. The solutions for all problems are included, making the book ideal for self-study. Problems are grouped into sections headed by an introduction and a list of new terms. By using practical computing to explore sequence data in an evolutionary context, the book enables readers to tackle their own computational problems.
    Type of Medium: Online Resource
    Pages: IX, 411 p. 155 illus., 46 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031204142
    DDC: 570.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Telecommunication. ; User interfaces (Computer systems). ; Human-computer interaction. ; Application software. ; Industrial engineering. ; Production engineering. ; Computational and Systems Biology. ; Communications Engineering, Networks. ; User Interfaces and Human Computer Interaction. ; Computer and Information Systems Applications. ; Industrial and Production Engineering.
    Description / Table of Contents: Introduction -- Emerging Industrial Revolution -- IoT: What makes it different from the past revolutions -- World is changing -- Engineering: How It was developed so far -- Humans: Their characteristics -- Value is changing -- Adaptive team organization and management -- Integration of Physical Science and Life Science -- Summary.
    Abstract: .
    Type of Medium: Online Resource
    Pages: XI, 70 p. 44 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030515881
    Series Statement: SpringerBriefs in Applied Sciences and Technology,
    DDC: 570.285
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Industrial microbiology. ; Bioinformatics. ; Synthetic Biology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Industrial Microbiology. ; Computational and Systems Biology. ; Synthetic Biology.
    Description / Table of Contents: Part 1 Introduction to Microbial Engineering -- 1 Exploring the Potential of Microbial Engineering: The Prospect, Promise and Essence -- Part 2 Microbial Engineering Approaches -- 2 Role of System Biology in Microbial System -- 3 Synthetic Biology: Refining Human Health -- 4 Probiotic Engineering: A focus on Inflammatory Bowel Disease -- 5 Engineering microbes for smart diagnostics & Lab on Chip -- 6 Bacteriophage and Virus Engineering -- 7 CRISPR Technologies: A tool for Engineering Microbes -- Part 3 Health Benefits -- 8 Recombinant Vaccines: The Revolution Ahead -- 9 Microbe-Host Metabolic Interaction- Probiotic Approach -- 10 Designer Microbes: Oncotherapy approach -- 11 The human gut microbiome in health, disease and therapeutics -- 12 Use of Engineered Bacteria for Production of Green Chemicals & Pharmaceuticals -- 13 Fat Fighting Microbes. Part 4 Innovation & Translation -- 14 Scale-up of engineering strain for industrial applications -- 15 Affordable therapeutics through Engineered Microbes -- 16 COVID-19: Lesson Learnt from Diagnostics to therapeutics. .
    Abstract: This book highlights the recent advances in the field of microbial engineering and its application in human healthcare. It underscores the systemic and synthetic biology approaches for engineering microbes and discusses novel treatments for inflammatory bowel diseases based on engineered probiotics. The book also reviews the different options and methods for engineering microbes, ranging from recombinant DNA technology to designing microbes for targeting specific sites and delivering therapeutics. Further, it discusses genetically engineered microorganisms for smart diagnostics and describes current approaches in microbial gene editing using CRISPR-Cas9-based tools. Lastly, it summarizes the potential applications of human microbiome engineering in improving human health and explores potential strategies for scaling-up the production of engineered microbial strains for commercial purposes, as well as the challenges. Given its scope, this book is a valuable resource for students, researchers, academics and entrepreneurs interested in understanding microbial engineering for the production of commercial products.
    Type of Medium: Online Resource
    Pages: XI, 374 p. 45 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811939792
    DDC: 610.72
    Language: English
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  • 66
    Keywords: Cancer. ; Oncology. ; Medical genetics. ; Bioinformatics. ; Microtechnology. ; Microelectromechanical systems. ; Cancer Biology. ; Oncology. ; Medical Genetics. ; Bioinformatics. ; Microsystems and MEMS.
    Description / Table of Contents: Module 1_ Introduction -- Module 2_ Cancer Metastasis -- Module 3_ Role of Transcriptomics in cancer treatment strategies -- Module 4_Computational approaches -- Module 5_Biostatistics and clinical oncology -- Module 6_Pharmacogenomics in cancer -- Chapter 7_Case studies.
    Abstract: This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.
    Type of Medium: Online Resource
    Pages: XVIII, 499 p. 59 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811510670
    DDC: 571.978
    Language: English
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  • 67
    Keywords: Plant diseases. ; Bioinformatics. ; Invertebrates. ; Plant Pathology. ; Computational and Systems Biology. ; Bioinformatics. ; Invertebrate Zoology.
    Description / Table of Contents: Chapter 1. Application of Geospatial Technologies in Plant Health Management -- Chapter 2. Applications of Unmanned Aerial System for Pest Surveillance, Monitoring and Management -- Chapter 3. Unmanned Aerial System Technologies for Pesticide Spraying -- Chapter 4. Insect Pest Detection, Migration and Monitoring Using Radar and LiDAR Systems -- Chapter 5. Remote Sensing, Climate Change and Insect Pest: Can Biotic Interactions be Explored? -- Chapter 6. Use of Mobile Apps and Software Systems for Retrieving and Disseminating Information on Pest and Disease Management -- Chapter 7. Harnessing Host Plant Resistance for major crop pests: Decoding In-Built Systems -- Chapter 8. Light Trap: A Dynamic Tool for Data Analysis, Documenting and Monitoring Insect Populations and Diversity -- Chapter 9. Artificial Diet Designing: Its Utility in Management of Defoliating Tea Pests (Lepidoptera: Geometridae) -- Chapter 10. Functional Diversity of Infochemicals in Agri-ecological Networks -- Chapter 11. Soil Fauna In Sustainable Agriculture -- Chapter 12. Pest Management in Tropical Forests -- Chapter 13. Non-Chemical Pest Management Approaches in Tea Ecosystem: Evading Pesticide Trap -- Chapter 14. Endophytes: A Potential Bio-agent for the Plant Protection -- Chapter 15. Insect Vectors of Phytoplasma Diseases in the Tropics: Molecular Biology and Sustainable Management -- Chapter 16. Hymenopteran Parasitoids in Cultivated Ecosystems: Enhancing Efficiency -- Chapter 17. Large Scale Production of Cotton Bollworm, Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) Nuclear Polyhedrosis Virus (HaNPV) -- Chapter 18. Insecticide Toxicity and Pesticide Residues in Horticultural Crops -- Chapter 19. Nano-technology Applications in Pest Management -- Chapter 20. Integrated and Ecological based Pest Management in Grape Ecosystem -- Chapter 21. Coccinellids on Crops: Nature’s Gift for Farmers -- Chapter 22. Scenario of Insect Pests on Litchi: Management Options -- Chapter 23. IPM in Protected Cultivation: Lending Pesticide Free Produce -- Chapter 24. Integrated Nematode Management In Protected Cultivation.
    Abstract: Several Integrated Pest Management (IPM) approaches are available for managing pests of varied kinds, including individual and integrated methods for pest suppression. Recently the focus has shifted to pest management tools that act on insect systems selectively, are compatible with the environment, and are not harmful for ecosystems. Other approaches target specific biochemical and physiological aspects of insect metabolism, and involve biotechnological and genetic manipulation. Still other approaches include the use of nanotechnology, endophytes, optical and sonic manipulation to detect and control pest insects. Unfortunately, conventional forms of pest management do not focus on technology transfer to the ground level workers and farmers. As a result, farmers are incurring huge losses of crops and revenues. This book highlights the importance of using communication tools in pest management and demonstrates some success stories of utilizing automated unmanned technologies in this context. The content is divided into three sections, the first of which, “Pest Population Monitoring: Modern Tools,” covers long and short-range pest population monitoring techniques and tools such as satellites, unmanned aerial vehicles/drones, remote sensing, digital tools like GIS, GPS for mapping, lidar, mobile apps, software systems, artificial diet designs and functional diversity of info-chemicals. The second section of the book is devoted to “Emerging Areas in Pest Management” and offers a glimpse of diversified tactics that have been developed to contain and suppress pest populations such as endophytes, insect vectors of phytoplasma, Hymenopterans parasitoids, mass production and utilization of NPV etc. In turn, the third section focuses on “Integrated Pest Management” and presents farming situations that illustrate how research in diversified aspects has helped to find solutions to specific pest problems, and how some new and evolving tactics can be practically implemented. Given its scope, the book offers a valuable asset for entomology and plant pathology researchers, students of zoology and plant protection, and readers whose work involves agriculture, horticulture, forestry and other ecosystems. .
    Type of Medium: Online Resource
    Pages: XIX, 519 p. 233 illus., 145 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811507946
    DDC: 571.92
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Nanotechnology. ; Immunology. ; Human physiology. ; Stem cells. ; Biomedical Research. ; Nanotechnology. ; Immunology. ; Human Physiology. ; Stem Cell Biology.
    Description / Table of Contents: Chapter 1_Introduction to NanoScience, NanoTechnology, and NanoParticles -- Chapter 2_NanoScience and Bioprospecting -- Chapter 3_Nanomaterials and their use in Biomedicine -- Chapter 4_Nano scaffolds and Tissue Engineering -- Module 5_NanoScience Research in Regenerative Medicine -- Chapter 6_Nanomaterials in Food: Probiotics -- Chapter 7_Eco-compatible Single format Nanobioantibody -- Chapter 8_ NanoScience and DNA barcoding.
    Abstract: This book comprehensively reviews the history of nanotechnology, and describes the physiochemical properties of various nanoparticles and their biomedical applications. Covering the biotoxicity of nanoparticles, their bio-distribution and release kinetics, and their role in diagnosis, pre-clinical drug discovery and disease prevention, it also examines the application of nanoscaffolds in tissue engineering and as cell culture templates. Further, the book discusses several fabrication methodologies for regenerative medicine, and explores nanotechnology-based stem cell therapeutics, including stem cell transfection, stem cell delivery, and stem cell expansion for promoting tissue regeneration. Lastly, it addresses the use of DNA barcoding technology from nanosamples for the detection, identification and validation of emerging pathogens, biodiversity and ancient remnants of living specimens, and highlights various strategies for the plant-mediated synthesis of nanoparticles. Given its scope, it is a valuable reference resource for graduate students and researchers interested in understanding the diverse range of biomedical applications of nanoparticles. .
    Type of Medium: Online Resource
    Pages: XVIII, 134 p. 13 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811552748
    DDC: 610.72
    Language: English
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  • 69
    Keywords: Medicine Research. ; Biology Research. ; Nanotechnology. ; Cancer Treatment. ; Biomedical Research. ; Nanotechnology. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1. The tumor microenvironment -- Chapter 2. Methods of formulation of polymeric nanoparticles -- Chapter 3. Natural polymers based nanoparticles targeted to solid tumors -- Chapter 4. Optimization of physicochemical properties of polymeric nanoparticles for targeting solid tumors -- Chapter 5. Passive and active targeting approaches for solid tumors -- Chapter 6. Polymeric nanoparticles entrapping natural drugs for cancer therapy -- Chapter 7. Polymeric nanoparticles entrapping drug combinations targeted to solid tumors -- Chapter 8. Ligands specific to over-expressed receptors in solid tumors -- Chapter 9. Ligand targeted polymeric nanoparticles for cancer chemotherapy -- Chapter 10. Polymeric nanoparticles as theranostics for targeting solid tumors -- Chapter 11. Oral delivery of polymeric nanoparticles for solid tumors -- Chapter 12. Polymeric nanoparticles to target glioblastoma tumors -- Chapter 13. Polymeric nanoparticles to target lung cancer -- Chapter 14. Polymer based nanoplatforms for targeting breast cancer -- Chapter 15. PH-Sensitive polymeric nanoparticles for cancer treatment -- Chapter 16. Polymeric nanoplatforms for targeted treatment of prostate cancer -- Chapter 17. Cellular internalization and toxicity of polymeric nanoparticles -- Chapter 18. Prospects and challenges in the treatment of solid tumors.
    Abstract: This book focuses on the emerging research in the field of treatment of solid tumors or cancer with new drug delivery systems using nanotechnology. Nanotechnology has given us a good scope for development of new innovative drug delivery strategies to increase the therapeutic efficacy of anticancer drugs with reduced off-target side effects. Cancer is one of the main causes of death worldwide due to the limitations of classical therapies such as low solubility of active drugs, toxic side effects on healthy cells and resistance of tumor cells. These issues are partly solved by the recent development of polymeric nanoparticles, which improve drug absorption and the therapeutic index, while reducing side effects. Drug carriers must be biocompatible, biodegradable and non-immunogenic. Coupled to a ligand that has affinity for that particular cell, polymeric nanoparticles are used to target specifically malignant cells or tissues and, in turn, improve drug stability. This book presents the latest advances in the application of polymeric particles for cancer treatment, with focus on the tumor microenvironment, synthesis, active and passive targeting, patents, targeting over-expressed receptors, tumor-targeting ligands, theranostics, glioblastoma tumors, lung cancer, breast cancer, prostate cancer and pH-responsive nanoparticles.
    Type of Medium: Online Resource
    Pages: X, 512 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031148484
    Series Statement: Environmental Chemistry for a Sustainable World, 71
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Human physiology. ; Nanotechnology. ; Biology Technique. ; Pharmacology. ; Human Physiology. ; Nanotechnology. ; Experimental Organisms. ; Pharmacology.
    Description / Table of Contents: Chapter 1. Synthesis and characterization of nanoparticles used in consumer products -- Chapter 2. Model organisms for in vivo assessment of nanoparticles -- Chapter 3. Impact of nanoparticles on behavior and physiology of Drosophila melanogaster -- Chapter 4. Dose-dependent influence of nanoparticles on fertility and survival -- Chapter 5. Effect of nanoparticles on maintenance of metabolic homeostasis -- Chapter 6. Nanoparticles: an activator of oxidative stress -- Chapter 7. Safe dose of nanoparticles: A boon for consumer goods and biomedical application.
    Abstract: This book offers an unparalleled source of information on in vivo assessment of nanoparticle toxicity by using Drosophila as a model organism. Nanoparticles have emerged as an useful tool for wide variety of biomedical, cosmetics, and industrial applications. However, our understanding of nanomaterial-mediated toxicity under in vivo condition remains limited. The book begins with a chapter on synthesis and characterization of nanoparticles used for various biological, medical and commercial purposes. The rest of the chapters deal with the impact of nanoparticles on different biological aspects like behavior, physiology and metabolic homoeostasis using Drosophila as a model organism. Lastly, the book summarizes how proper characterization and evaluation of safe dosage of nanoparticles can be a boon if incorporated in consumer goods and for biomedical applications. Overall, the book pursues an interdisciplinary approach by connecting nanotechnology and biology from various angles using Drosophila as a model system, so as to develop more efficient, safe and effective use of nanoparticles for human beings.
    Type of Medium: Online Resource
    Pages: XII, 122 p. 34 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811555220
    DDC: 612
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant biotechnology. ; Nanotechnology. ; Microbiology. ; Botanical chemistry. ; Freshwater ecology. ; Marine ecology. ; Plant Biotechnology. ; Nanotechnology. ; Microbiology. ; Plant Biochemistry. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Preface -- Introduction: Nanotechnology and Nanobiotechnology, Different Types of Nanomaterials, and General Characterization Techniques -- Microbial Synthesis of Different Nanomaterials using Prokaryotic Microorganisms (Bacteria and Actinomycetes) -- Microbial Synthesis of Different Nanomaterials using Prokaryotic Microorganisms (Bacteria and Actinomycetes) -- Photosynthesis of Different Nanomaterials Using Different Plant Extracts and the Extracts of Agro-Industrial Waste (Phytonanotechnology) -- Different Application Fields of Biologically Synthesized Nanoparticles -- Safety of Prepared Nanomaterials and Future Prospectives -- Bibliography -- Index.
    Abstract: The generation of well-defined nanoparticles of excellent size and shape involves physical and chemical methodologies that are complicated, expensive, and produce hazardous toxic waste that is harmful to the environment and to human health. In order to combat the disadvantages of these methods, scientists have created “the biological method,” a new synthetic methodology that serves as a proper alternative to physical and chemical methodologies because of its easy utility, low cost, rapid synthesis, controlled size characteristics, controlled toxicity, and eco-friendliness. Nanobiotechnology is the science in which living matter can be manipulated and exploited to produce materials within the nano-scale. It is a multidisciplinary field of science framed by biology, chemistry, engineering, materials, and life sciences. Different biological entities can be exploited to yield biologically synthesized nanomaterials including bacteria, actinomycetes, yeast, fungi, viruses, algae, plant extracts, and agro-industrial waste extracts. This book represents a comprehensive review concerning the state of the art in nanobiotechnology, emphasizing the use of diverse biological entities in the science, and its versatile applications. It describes currently existing methodology with the latest published references, and provides safety information. It serves as the ideal guide for scientists interested in exploring nanobiotechnology.
    Type of Medium: Online Resource
    Pages: XX, 230 p. 13 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030460716
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 631.52
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Conservation biology. ; Ecology . ; Animal culture. ; Vertebrates. ; Bioinformatics. ; Anthropology. ; Conservation Biology. ; Animal Science. ; Vertebrate Zoology. ; Computational and Systems Biology. ; Anthropology.
    Description / Table of Contents: Tourism and Indonesia’s Primates: An Introduction- Similar Perceptions of National and International Volunteer Ecotourists Contribute to the Conservation of the Critically Endangered Javan Slow Loris in Java, Indonesia -- Bukit Lawang and Beyond: Primates and tourism from a provider’s perspective -- Rethinking Tolerance to Tourism: Behavioral responses by wild crested macaques (Macaca nigra) to tourists -- The Effect of Tourism on a Nocturnal Primate, Tarsius spectrum, in Indonesia -- Javan Gibbon Tourism: A Review from West and Central Java Initiatives -- Encountering Sulawesi’s Endemic Primates: Considerations for developing primate tourism in South Sulawesi, Indonesia -- Primates and Primatologists: Reflecting on two decades of primatological and ethnoprimatological research, tourism, and conservation at the Ubud Monkey Forest -- Primate tourism on Java: 40 years of ebony langur viewing in Pangandaran from homestay visits to mass tourism -- Indigenous Bird Ecotourism in Halmahera Island, Indonesia. .
    Abstract: The basic goal of the volume is to compile the most up to date research on the effect of ecotourism on Indonesia’s primates. The tremendous diversity of primates in Indonesia, in conjunction with the conservation issues facing the primates of this region, have created a crisis whereby many of Indonesia’s primates are threatened with extinction. Conservationists have developed the concept of “sustainable ecotourism” to fund conservation activities. National parks agencies worldwide receive as much as 84% of their funding from ecotourism. While ecotourism funds the majority of conservation activities, there have been very few studies that explore the effects of ecotourism on the habitat and species that they are designed to protect. It is the burgeoning use of “ecotourism” throughout Indonesia that has created a need for The Ecotourism of Indonesia's Primates where the successes and pitfalls at various sites can be identified and compared.
    Type of Medium: Online Resource
    Pages: VIII, 220 p. 48 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031149191
    Series Statement: Developments in Primatology: Progress and Prospects,
    DDC: 333.9516
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cytology. ; Regenerative medicine. ; Medicine Research. ; Biology Research. ; Bioinformatics. ; Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Research. ; Bioinformatics.
    Description / Table of Contents: Involvement of Endothelial Nitric Oxide Synthase in Cerebral Microcirculation and Oxygenation in Traumatic Brain Injury -- Imaging cerebral energy metabolism in healthy infants -- Changes in cerebral oxygenation and systemic physiology during a verbal fluency task: Differences between men and women -- Brain Tissue Conductivity in Focal Cerebral Ischemia -- Physical stress Attenuates Cognitive inhibition: An fNIRS Examination -- Changes in Prefrontal Cortical Oxygenation During Tilt Table Orthostatic Hypotension in Subarachnoid Haemorrhage Patients -- Effects of different optical properties of head tissues on near-infrared spectroscopy Using Monte Carlo Simulations -- Frontal cerebral oxygenation in humans at rest: A mirror symmetry in the correlation with cardiorespiratory activity -- Photomodulation of lymphatic delivery of bevacizumab to the brain: the role of singlet oxygen -- NIRS-based study of local cerebral oxygenation during transcranial direct current stimulation in patients with mild traumatic brain injury -- Postnatal Exposure to Brief Hypoxia Alters Brain VEGF Expression and Capillary Density in Adult Mice -- Impaired Cognitive Performance in Mice Exposed to Prolonged Hyperoxia -- Chronic Ketosis Modulates HIF1α-Mediated Inflammatory Response in Rat Brain -- Motor Imagery and Frontal Head Oxygenation: An fNIRS Study -- Non-invasive detection of persistent cortical hypoxia in Multiple Sclerosis using frequency domain near-infrared spectroscopy (fdNIRS) -- Evaluation of intraoperative end-tidal Carbon dioxide change relates to length hospitalization in peridiaphragmatic surgery: a pilot study -- Pulmonary Embolism in COVID-19 patients is not related to a worsening in tissue oxygenation -- Cardiovascular risk score and gas exchange in COVID-19 patients: no correlation -- Heme Oxygenase 1/ High Mobility Group Box 1 pathway may have a possible role in Covid-19 ARDS (Acute respiratory distress syndrome): a pilot histological study -- Silent Hypoxemia in COVID-19 pneumonia -- Low Flow and Microvascular Shunts: A Final Common Pathway to Cerebrovascular Disease: A Working Hypothesis -- A case of intracranial vertebral artery stenosis treated with percutaneous transluminal angioplasty and stenting guided by brain oximetry -- Assessment of Optimal Arterial Pressure with Near-Infrared Spectroscopy in Traumatic Brain Injury Patients -- Effects of exercise-diet therapy on cognitive function in healthy elderly people evaluated by deep learning based on basic blood test data -- NIRS studies show reduced interhemispheric functional connectivity in individuals with Multiple Sclerosis that exhibit cortical hypoxia -- Eye Tracking Parameters Correlate With the Level of Cerebral Oxygen Saturation in Mild Traumatic Brain Injury: A Preliminary Study -- Critical closing pressure of cerebral circulation at concomitant moderate-to-severe traumatic brain injury -- Hybrid convolutional neural network (hCNN) for image reconstruction in near-infrared optical tomography -- Cross-frequency coupling between brain and body biosignals: A systemic physiology augmented functional near-infrared spectroscopy hyperscanning study -- Machine learning distinguishes familiar from unfamiliar pairs of subjects performing an eye contact task: A systemic physiology augmented functional near-infrared spectroscopy hyperscanning study -- Assessing Neurovascular Coupling Using Wavelet Coherence in Neonates With Asphyxia -- Basic examination of hemoglobin phase of oxygenation and deoxygenation in resting state and task periods in adults using fNIRS -- Development and validation of robust and cost-effective liquid heterogeneous phantom for time domain near-infrared optical tomography -- Effect of Exercise Therapy on Stress Response Evaluated by IoMT Monitoring System -- Improved optical tissue model for tissue oximetry imaging applications -- In vitro validation of a new tissue oximeter using visible light -- Photon and Proton Dose Painting based on Oxygen Distribution – Feasibility Study and Tumour Control Probability Assessment -- Effect of Acidosis-Induced Signalling Pathways on Mitochondrial O2 Consumption of Tumour Cells -- Feasibility of non-invasive measurement of tumor NAD(H) by in vivo phosphorus-31 magnetic resonance spectroscopy -- Acidosis-induced regulation of Egr1 and Ccn1 in vitro and in experimental tumors in vivo -- Perfusion-Limited Hypoxia Determines the Outcome of Radiation Therapy of Hypoxic Tumours -- Improved Oxygenation of Human Skin, Subcutis and Superficial Cancers upon Mild Hyperthermia Delivered by wIRA-Irradiation -- Blood Supply and Oxygenation Status of the Liver: From Physiology to Malignancy -- Optical Redox Imaging Is Responsive to TGFβ Receptor Signaling in Triple-Negative Breast Cancer Cells -- Evaluation of betulinic acid derivatives as PET tracers for hypoxia-induced carbonic anhydrase IX (CA IX) expression -- Role of the mTOR signaling pathway during extracellular acidosis in tumor cells -- Feasibility Study of Remote Contactless Perfusion Imaging with Consumer-Grade Mobile Camera -- Stability of a Novel PEGylation site on a Putative Hemoglobin Based Oxygen Carrier -- Oxygen storage in stacked phospholipid membranes under an oxygen gradient as a model for myelin sheaths -- Confocal laser and electron microscopic investigation of gap junctions in anaplastic astrocytomas -- A radiation biological analysis of the oxygen effect as a possible mechanism in FLASH -- Assessment of nicotinamide adenine dinucleotide in human tissues by in vivo phosphorus-31 magnetic resonance spectroscopic imaging at 1.5 Tesla -- Drag-Reducing Polymers Improve Vascular Hemodynamics and Tissue Oxygen Supply in Mouse Model of Diabetes Mellitus -- Hemorheologic Enhancement of Cerebral Perfusion increases oxygen supply and reduces Ab plaques deposition in a mouse model of Alzheimer’s Disease -- Calorimetric Characterization of the Binding Reaction Between Human Ferric Hemoglobins and Haptoglobin to Develop a Drug for Removal of Cell-Free Haemoglobin -- Feasibility To Measure Tissue Oxygen Saturation Using Textile-integrated Polymer Optical Fibers -- Effect of Atorvastatin on Microcirculation Evaluated by Vascular Occlusion Test with Peripheral Near lnfrared Spectroscop -- Flow characteristics of the conjugate of anti-CD3 monoclonal antibodies and magnetic nanoparticle in the PBS and the blood vessel -- Cerebrovascular Reserve (CVR) and Stages of Hemodynamic Compromise -- On the mechanism of sustained mitochondrial membrane potential without functioning complex IV -- Further evidence that gradients of extracellular pH direct migration of MDA-MB-231 cells in vitro -- Blood Flow and Respiratory Gas Exchange in the Human Placenta at Term: A Data Update -- Oxyhaemoglobin Level Measured Using Near-Infrared Spectrometer is Associated with Brain Mitochondrial Dysfunction After Cardiac Arrest in Rats -- Changes in Oxygenation Levels During Moderate Altitude Simulation (Hypoxia-Induced): A Pilot Study Investigating the Impact of Skin Pigmentation in Pulse Oximetry -- The Intramuscular Circulation is Affected by Neck and Shoulder Pain -- Intramuscular circulation of the lumbar multifidus in different trunk positions on standing -- Numerical Optimization of a NIRS Device for Monitoring Tissue Oxygen Saturation -- Upper trapezius muscle tonicity, assessed by palpation, relates to change in tissue oxygenation and structure as measured by Time-Domain Near Infrared Spectroscopy -- Perceived exertion correlates with multiple physiological parameters during cardiopulmonary exercise testing -- Systemic and Quadriceps Muscle O2 Dynamics in Subjects without Attenuation Point of Deoxygenated Hemoglobin Concentration during Ramp Cycling Exercise -- Jaw-Clenching Intensity Effects on Masseter Oxygen Dynamics and Fatigue: A NIRS Oximetry Study. .
    Abstract: This book contains most of the scientific contributions during the 48th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), which was held electronically in July 2021. It includes multidisciplinary contributions from scientists (physicists, biologists and chemists), engineers, clinicians and mathematicians and covers covers all aspects of oxygen transport from air to the cells, organs and organisms; instrumentation and methods to sense oxygen and clinical evidence.
    Type of Medium: Online Resource
    Pages: XXVI, 446 p. 163 illus., 100 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031141904
    Series Statement: Advances in Experimental Medicine and Biology, 1395
    DDC: 571.6
    Language: English
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    Keywords: Bioinformatics. ; Information visualization. ; Arts. ; Computational and Systems Biology. ; Data and Information Visualization. ; Fine Art.
    Description / Table of Contents: The Deadly Beauty of Cancer -- Cellular Connections -- Annealing Party -- Cells on the Ferris Wheel -- The Magic Pants that Always Fit -- Racing Triangles -- Rising Dragons -- Henri in Wonderland -- Peak of the Iceberg -- Guiding Spiral -- The Hidden Beauty of Roots -- The Beauty of a Beast -- The Ghost -- Lymph Node Landscapes -- Breezing Drops -- Labyrinths: Exotic Patterns of Cortical Activity -- Mammalian Lipidomic Network -- One Step at a Time -- How a Tumor Gets its Spots -- Patchwork Patterns -- Cancer Warfare -- Collective Decision Making -- Cell Simulation in Blossom -- Semblance of Heterogeneity -- Can we Crack Cancer? -- Dance with Predators and Prey -- Knitting Proteins -- Nothing Stands Still in the Streams of Life -- Restless Mind Wandering -- Morphological Echoes -- Cancer as a Killer Tsunami -- Cells Are Watching You -- Roots or Flowers? Take a Guess... -- Spectral Forms and Cosmic Storms -- Antigenic Explosion -- Crop Circles of Cancer -- Scalp -- Coupled Invasion -- Lost in the Cells -- Becoming Important -- Community Matters -- Acidic Dance -- Flocking, Swirling and Spinning Stars in a Cell -- A Mosaic of Cancer and Liver Tissue -- Cell Firework -- Pulled in Line -- Convergence -- Arctic Breeze -- Extracellular Galaxies -- Oriental Landscape Painting by Predator Species -- Life is Lived on the Edge -- Cellular Swarms in Cellular Automata -- Bumps, Ridges, and no Flows in Vein -- Growing Orbs / Mingled Metabolism -- Out of the Comfort Zone -- Green Protein Interaction Wheel -- Vincent van Gogh’s Autocatalysis -- Clonal Inferno -- What Lies Beneath (the Heartbeat) -- Tree of Life -- Tower of Life -- Clone Wars - The Immune System Awakens -- Modelled Cell -- CD196- -- Tumor Composition Depends on the Viewing Angle -- Poincaré’s Homoclinic Horror -- E/A/S (Evolving Asteroid Starships) -- Interacting Spider Webs -- Heart Cells are aMAZEing -- Actin Spring -- Dynamical Diggers.
    Abstract: This beautifully crafted book collects images, which were created during the process of research in all fields of theoretical biology. Data analysis, numerical treatment of a model, or simulation results yield stunning images, which represent pieces of art just by themselves. The approach of the book is to present for each piece of visualization a lucid synopsis of the scientific background as well as an outline of the artistic vision. .
    Type of Medium: Online Resource
    Pages: X, 152 p. 72 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030334710
    DDC: 570.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Molecular biology. ; Linguistics. ; Bioinformatics. ; Evolution (Biology). ; Knowledge, Theory of. ; Philosophy of nature. ; Molecular Biology. ; Linguistics. ; Bioinformatics. ; Evolutionary Biology. ; Epistemology. ; Philosophy of Nature.
    Description / Table of Contents: Language: Gateway to the World -- Truth: The Regulative Principle of Cognition -- Methods: Ways of Gaining Knowledge -- Unity: The Deep Structure of Science -- Limits: Insights into the Reach of Science -- Perspectives: Designing Living Matter -- Epilogue: Nature’s Semantics -- Author Index -- Subject Index.
    Abstract: This book, by an eminent scientist and philosopher, provides strong evidence for the claim that language is a general principle of Nature, rooted exclusively in physical and chemical laws. The author’s radical idea inevitably leads us to view the essence, origin and evolution of life in a completely new light. It shifts the coordinates of our scientific world-view in favor of an overarching concept of language that is able to bridge the gap between matter and mind. At the same time, it removes a blind spot in the Darwinian concept of evolution. To justify this far-reaching idea, the book takes a long and deep look at our scientific and philosophical thinking, at language as such, at science’s claim to truth, and at its methods, unity, limits and perspectives. These are the cornerstones structuring the book into six thematically self-contained chapters, rounded off by an epilogue that introduces the new topic of Nature’s semantics. The range of issues covered is a testimony to how progress in the life sciences is transforming the whole edifice of science, from physics to biology and beyond. The book is aimed at a broad academic and general readership; it requires no mathematical expertise.
    Type of Medium: Online Resource
    Pages: XIX, 511 p. 110 illus., 106 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030803193
    Series Statement: The Frontiers Collection,
    DDC: 572
    Language: English
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    Keywords: Regenerative medicine. ; Stem cells. ; Biomaterials. ; Nanotechnology. ; Drug delivery systems. ; Biomedical engineering. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology. ; Biomaterials. ; Nanotechnology. ; Drug Delivery. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Introduction of Biomaterials and Tissue Engineering -- Chapter 2. Tissue regeneration processing and mimicking -- Chapter 3. Cell sources for Tissue Engineering -- Chapter 4. Biomaterials -- Chapter 5. Micro and nanotechnology -- Chapter 6. Bioceramics -- Chapter 7. Drug delivery for Tissue Engineering -- Chapter 8. Cell-material interaction -- Chapter 9. Bioreactors -- Chapter 10. Scaffolds fabrication processes -- Chapter 11. Characterization of the biological response to scaffolds -- Chapter 12. Additive Manufacturing -- Chapter 13. Bioprinting -- Chapter 14. Outlook and future perspectives.
    Abstract: This contributed volume covers all fundamental principles for researchers and professionals interested in the field of Biomaterials and Tissue Engineering, an interdisciplinary field of research with contributions from biomedical scientists, engineers, and physicians. With a strong focus on biomaterials and scaffolds, the book also covers testing and evaluation pathways for in vitro and in vivo studies. This book also presents a broad range of topics including fundamentals of 3D printing and bioprinting, followed by contemporary technology used in tissue engineering applications as well as currently available biomaterials suitable for tissue repair and regeneration. This volume provides information on: (i) why humans need biomaterials, especially in medical applications, (ii) different types of tissue engineering strategies, and (iii) modeling, characterization, and evaluation of outputs of those strategies. This book is a reference material in the field of tissue engineering, and it is very useful for bachelor, M.Sc., and Ph.D. students, researchers, academics, medical, industry, and healthcare professionals from diverse backgrounds.
    Type of Medium: Online Resource
    Pages: XII, 387 p. 118 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031358326
    Series Statement: Stem Cell Biology and Regenerative Medicine, 74
    DDC: 612.028
    Language: English
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  • 77
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Bioinformatics. ; Biotechnology. ; Computational and Systems Biology.
    Description / Table of Contents: Web-based 3D visualisation of biological and medical data -- Ultrasound-Guided Regional Anaesthesia: Visualising Nerve and Needle -- Scanning conditions in functional connectivity magnetic resonance imaging: how to standardise resting-state for optimal data acquisition and visualisation? -- Interactive VR Stroke Rehabilitation System Design -- Systematic review of Augmented and Virtual Reality in anatomical education -- Interdimensional travel: Visualisation of 3D-2D transitions in anatomy learning -- Anatomy Visualizations Using Stereopsis: Assessment and Implication of Stereoscopic Virtual Models in Anatomical Education -- Storyboarding in Medical Animation -- The hidden curriculum of imaging and utilisation of unregulated social media resources within clinical education -- Online distance learning in biomedical sciences: Community, belonging and presence. .
    Abstract: This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will be able to explore the utilisation of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences, with a focus in this volume related to anatomy, and clinically applied scenarios. The first eight chapters examine a variety of tools, techniques, methodologies and technologies which can be utilised to visualise and understand biological and medical data. This includes web-based 3D visualisation, ultrasound, virtual and augmented reality as well as functional connectivity magnetic resonance imaging, storyboarding and a variety of stereoscopic and 2D-3D transitions in learning. The final two chapters examine the pedagogy behind digital techniques and tools from social media to online distance learning techniques.
    Type of Medium: Online Resource
    Pages: XV, 181 p. 69 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030376390
    Series Statement: Advances in Experimental Medicine and Biology, 1235
    DDC: 660.6
    Language: English
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  • 78
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant biotechnology. ; Nanotechnology. ; Agriculture. ; Plant ecology. ; Green chemistry. ; Biochemistry. ; Plant Biotechnology. ; Nanotechnology. ; Agriculture. ; Plant Ecology. ; Green Chemistry. ; Biochemistry.
    Description / Table of Contents: Preface -- New approaches for renewable energy using metal electrocatalysts for lithium-O2 and zinc-air batteries -- Biodiesel production for the sustainable development of chemical industry -- Cellulose based green and sustainable energy -- Design of dithienopyrrole-based organic dyes for efficient dye-sensitized solar cells: Strategies and outcome -- Sonochemical production of hydrogen: A novel approach -- Impact of alcohol and its blends on engine performance -- Photovoltaic performance of bipyridine and dipyridophenazine-based ruthenium complexes in application of dye-sensitized solar cell sensitizers -- Compressed fluids for food by-products biorefinery -- Green and sustainable biomass processing for fuels and chemicals -- Enriching of carotenes by supercritical desorption of buriti oil (Mauritia flexuosa Mart.) from alumina adsorbent -- Utilization of bio waste in green chemistry -- The role of heterogeneous catalysts in cellulose conversion to platform chemicals and biofuels -- Potential of neem oil as source of biodiesel -- Sustainable photocatalyst for energy and environment application -- Implementation guidelines for modelling gasification processes in computational fluid dynamics: A tutorial overview approach -- Sustainable cellulose based absorbents for heavy metal remediation -- Recent trend in photo-catalytic water of azo dyes -- Hospital effluents treatment -- Solar photocatalytic treatment of tannery effluent -- Modification of natural fibers by graft copolymerization and their environmental applications -- Dye degradation for environmental remediation -- Exploring natural coagulant application in the treatment of water for safe drinking -- Sustainable technologies for the wastewater treatment generated by leather industry sector: Regulation and economic aspects -- Physical and biological techniques to remediate carcinogenic Cr(VI) from industrial effluents -- Separation of industrial effluents -- Application of polymers in purification of industrial wastewater -- Role of disinfectants in green chemistry -- Sonochemistry in green processes: modeling, experiments and technology -- Biosynthesis of silymarin through plant in-vitro cultures -- Chemistry for new frontiers in supramolecular theranostics -- Cellulose nanocrystal aerogels: Synthesis, functional properties, and applications -- Graphene oxide: An efficient, and recyclable nano catalyst for the synthesis of 2-substituted benzimidazoles from aldehydes and diamines at ambient temperature -- Green synthesis of TiO2 nanomaterials photocatalyst -- Green corrosion inhibitors for industrial cleaning processes -- Cellulose amphiphilic materials: Chemistry, process, and applications -- Oleogels and their applications -- Measuring corrosion abrasion in various solid-fluid systems -- Base-free conversion of aldose sugar to aldonic acid -- Treatment of dairy products with conversion of useful bio-products -- Green corrosion inhibitor for petroleum pipelines -- Impact and challenges of polymerization -- Index.
    Abstract: Urbanization, industrialization, and unethical agricultural practices have considerably negative effects on the environment, flora, fauna, and the health and safety of humanity. Over the last decade, green chemistry research has focused on discovering and utilizing safer, more environmentally friendly processes to synthesize products like organic compounds, inorganic compounds, medicines, proteins, enzymes, and food supplements. These green processes exist in other interdisciplinary fields of science and technology, like chemistry, physics, biology, and biotechnology, Still the majority of processes in these fields use and generate toxic raw materials, resulting in techniques and byproducts which damage the environment. Green chemistry principles, alternatively, consider preventing waste generation altogether, the atom economy, using less toxic raw materials and solvents, and opting for reducing environmentally damaging byproducts through energy efficiency. Green chemistry is, therefore, the most important field relating to the sustainable development of resources without harmfully impacting the environment. This book provides in-depth research on the use of green chemistry principles for a number of applications.
    Type of Medium: Online Resource
    Pages: XI, 604 p. 150 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030422844
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 631.52
    Language: English
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  • 79
    Keywords: Cancer. ; Nanotechnology. ; Radiology. ; Molecular genetics. ; Cancer Biology. ; Nanotechnology. ; Radiology. ; Molecular Genetics.
    Description / Table of Contents: Chapter 1. Role of selected transcription factors in pancreatic and colorectal cancer growth and metastasis -- Chapter 2. Adiponectin in gastrointestinal malignancies -- Chapter 3. Small molecule-targeted therapies for GI cancers: success and failures -- Chapter 4. Epigenetic biomarkers for the detection of Gastrointestinal Cancers -- Chapter 5. CD151: A Lateral organizer and modulator of Tumor microenvironment in gastrointestinal cancers -- Chapter 6. Targeting Pathways in GI Malignancies -- Chapter 7. Identification of Potential Key Genes Involved In Progression of Gastric Cancer Using Bioinformatics Analysis -- Chapter 8. Recent Development in the biomarkers for the gastric cancer -- Chapter 9. Gastric Cancer and it’s remedy -- Chapter 10. An intergenic variant rs4779584 between SCG5 and GREM1 contributes to the increased risk of colorectal cancer: A meta-analysis -- Chapter 11. Phytochemicals plus nanomaterial’s on colorectal cancer -- Chapter 12. Pancreatic Ductal Adenocarcinoma and Type 2 Diabetes Mellitus: Distant Relatives or the Close Ones? -- Chapter 13. Tumor Biomarkers and Diagnosis of Pancreatic Adenocarcinoma -- Chapter 14. Immunotherapy in Gastrointestinal Malignancies -- Chapter 15. The Role of HIF-1α in Hepatocellular Carcinoma.
    Abstract: This book provides an up-to-date overview of gastrointestinal malignancies, including prevention, early detection, intervention, and life-extending therapeutics. It also assesses various biomarkers used for diagnostics, prognostics and prediction of response to chemoresistance. Further, it discusses the latest trends in the use of small-molecule targeted therapies and immunotherapies as single agents or combination with other treatments. Since resistance to radiation and chemotherapy contribute to the high recurrence and poor survival rates, improving the outcome for GI malignancies is dependent on the introduction of new biomarkers and therapeutic agents. Lastly, the book systematically investigates novel theranostics approaches using nanotechnology for the detection, diagnosis, and personalized treatment of GI malignancies.
    Type of Medium: Online Resource
    Pages: XII, 259 p. 53 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811554711
    Series Statement: Diagnostics and Therapeutic Advances in GI Malignancies,
    DDC: 571.978
    Language: English
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  • 80
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Enzymology. ; Proteins. ; Bioinformatics. ; Microbial genetics. ; Biotechnology. ; Enzymology. ; Proteins. ; Bioinformatics. ; Microbial Genetics.
    Description / Table of Contents: Chapter 1. Introduction to Glycoside Hydrolases: Classification, identification and Occurrence -- Chapter 2. Glycosyl Hydrolases – Biochemistry and Applications -- Chapter 3. Lignocellulolytic and Chitinolytic Glycoside Hydrolases: Structure, Catalytic -- Chapter 4. Role of glycosyl hydrolases in breakdown of lignocellulosic waste and its industrial applications -- Chapter 5. Marine glycosyl hydrolases as tool for industrial application -- Chapter 6. Glycosyl Hydrolases and Biofuel -- Chapter 7. Role of Glycoside hydrolases in pulp and paper industries -- Chapter 8. Application of glycosyl hydrolases in food industry -- Chapter 9. The effects of xylanase synergistic interactions during lignocellulose degradation and their significance for industry -- Chapter 10. Role of metagenomics in discovery of industrially important cellulase.
    Abstract: This book gathers selected studies on the industrial applications of glycoside hydrolases (GHs), presenting an updated classification of these enzymes, and discussing their structure, mechanisms, and various approaches to improve their catalytic efficiency. Further, it explains the various industrial applications of glycoside hydrolases in food, effluent treatment, biofuel production, and the paper and pulp industries. Lastly, the book provides a comparative analysis of glycosyide hydrolases and discusses the role of metagenomics in the discovery of industrially important enzymes. As such it is a thought-provoking, instructive and informative resource for biochemists, enzymologists, molecular biologists and bioprocess technologists. .
    Type of Medium: Online Resource
    Pages: XXI, 259 p. 35 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811547676
    DDC: 660.6
    Language: English
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  • 81
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Internal medicine. ; Bioinformatics. ; Biomedical Research. ; Internal Medicine. ; Bioinformatics.
    Description / Table of Contents: Part One: Basic Concepts in Precision Oncology -- Chapter 1. Design and Implementation of a precision oncology workflow -- Chapter 2. An overview of cancer genome sequencing -- Chapter 3. Software infrastructures for precision medicine workflows -- Part Two: Current Computational Methods and Tools in Precision Oncology -- Chapter 4. Somatic and germline variant calling from next-generation sequencing data -- Chapter 5. Identification of copy number alterations from next-generation sequencing data -- Chapter 6. Genome-wide discovery of large-scale structural variants from next-generation sequencing data -- Chapter 7. Assessment of microsatellite instability from next-generation sequencing data -- Chapter 8. Computational approaches for the investigation of intra-tumor heterogeneity and clonal evolution from bulk sequencing data -- Chapter 9. Analysis of the transcriptome for precision oncology applications -- Chapter 10. Computational methods for drug repurposing -- Chapter 11. Pathway for analysis for precision oncology applications -- Chapter 12. Identification of fusion transcripts from RNA-seq -- Chapter 13. Computational resources for the interpretation of variations in cancer -- Chapter 14. Analysis of electronic health records for precision oncology -- Chapter 15. Network approaches for precision oncology -- Chapter 16. Experimental validation of genomic alterations -- Part Three: Advanced Concepts - The Future of Precision Oncology -- Chapter 17. Molecular profiling of liquid biopsies for precision oncology -- Chapter 18. Artificial intelligence for precision oncology -- Chapter 19. Single-cell technologies in precision oncology -- Chapter 20. Computational approaches for precision immuno-oncology -- Chapter 21. Multi-pmics profiling of the tumor microenvironment -- Chapter 22. Epigenetic and precision oncology -- Chapter 23. Next generation knowledge bases to support precision oncology. .
    Abstract: Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology.
    Type of Medium: Online Resource
    Pages: XIV, 336 p. 36 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030918361
    Series Statement: Advances in Experimental Medicine and Biology, 1361
    DDC: 610.72
    Language: English
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  • 82
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Biological transport. ; Cell membranes. ; Analytical chemistry. ; Human physiology. ; Bioinformatics. ; Membrane Trafficking. ; Analytical Chemistry. ; Human Physiology.
    Description / Table of Contents: Chapter 1: The extracellular matrix goes - omics: resources and tools -- Chapter 2:The matrisome of model organisms: from in-silico prediction to big-data annotation -- Chapter 3: Detecting changes to the extracellular matrix in liver diseases -- Chapter 4: Characterization of Proteoglycanomes by Mass Spectrometry -- Chapter 5: Historical overview of integrated GAG-omics and proteomics -- Chapter 6: Extracellular matrix networks: from connections to functions -- Chapter 7: Integration of Matrisome Omics: Towards System Biology of the Tumor Matrisome -- Chapter 8: Proteomic and degradomic analysis of body fluids: applications, challenges and considerations -- Chapter 9: Regulation of Cell-Matrix Adhesion Networks: Insights from Proteomics -- Chapter 10: Integrative models for TGF- signaling and extracellular matrix.
    Abstract: This book covers different omics aspects related to the extracellular matrix (ECM), namely specific omics resources focused on the extracellular matrix (e.g., databases, repositories and atlases), quantitative proteomics applied to specific extracellular matrices (e.g. basement membranes), biological processes such as ECM degradation (degradomics), cell-matrix interactions (adhesomes), signaling pathways, biomarker discovery and diseases, and interactomics (extracellular matrix interaction networks including not only protein-protein but also protein-glycosaminoglycan interactions). The volume also includes recent advances in glycomics and glycobioinformatics applied to proteoglycans and glycosaminoglycans, which are key biological players. The use of omics data to build dynamic models of ECM-regulated biological pathways is addressed, together with the requirement to standardize omic data, which is a prerequisite for the FAIR (Findability, Accessibility, Interoperability, and Reusability) guiding principles for scientific data management. This book will be of great interest to a broad readership from beginners to advanced researchers, who are interested in extracellular matrix omics and will inspire future research topics. .
    Type of Medium: Online Resource
    Pages: VIII, 225 p. 22 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030583309
    Series Statement: Biology of Extracellular Matrix, 7
    DDC: 570.285
    Language: English
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  • 83
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Nanotechnology. ; Pharmaceutical chemistry. ; Cancer. ; Biotechnology. ; Nanotechnology. ; Pharmaceutics. ; Cancer Biology.
    Description / Table of Contents: Introduction to chemoprevention -- Phytochemical Bioactives in Chemoprevention -- Controlled Delivery of Chemopreventive Agents -- Nanochemoprevention -- Targeted Nanomedicine in Chemoprevention -- Miscellaneous Approaches of Chemoprevention -- Quality Control, Scale Up and Regulatory Aspects Of Herbal Nanomedicine.
    Abstract: This book discusses the recent progress and advances in nanochemoprevention. Chemoprevention utilizes natural dietary compounds and has regained interest due to larger safety window and proven efficacy of such molecules in cancer treatments. Nanotechnology has revolutionized drug delivery through passive as well as active targeting. This book provides a comprehensive overview of phytochemical bioactives that are used in chemoprevention. It gives a comprehensive overview of the variety of natural molecules and types of nanoparticles as well as mechanistic aspects of their superior efficacy over plain drug molecules. The book concludes with summarizing the progress of pre-clinical results of developed formulations for cancer treatment using nano-chemoprevention.
    Type of Medium: Online Resource
    Pages: XI, 95 p. 16 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811596926
    DDC: 660.6
    Language: English
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  • 84
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Bioinformatics. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Cytokine receptor signaling and CD4/CD8 lineage choice during T cell development in the thymus -- An agent-based model of T helper cell fate decisions in the thymus -- Modelling naive T cell homeostasis -- Mechanistic models of CD4 T cell homeostasis and reconstitution in health and disease -- Section 1MODELING THE DYNAMICS OF CD4+ T CELLS IN HIV- 1 INFECTION -- Modelling the response to Interleukin-7 therapy in HIV-infected patients -- Modeling immunopathology during persistent viral infections -- Delay in differentiation may suggest division of labour in models for CD8+ T cell differentiation -- Inferring differentiation order in adaptive immune responses from population level data -- Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes -- The public face and private lives of T cell receptor repertoires -- Population dynamics of immune repertoires -- Mathematical Modelling of T cell activation -- Agent-based model of heterogeneous T cell activation in vitro -- CTLA-4 mediated ligand trans-endocytosis: a stochastic model -- Automated gating and dimension reduction of high-dimensional cytometry data -- Index.
    Abstract: The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modelled. We aim in the proposed book to emphasise the role that mathematical (or computational) modelling has already played in Immunology. Each chapter will provide an example of the contribution of mathematics to T cell immunology under one of the following four headings: i) Generation of hypotheses, ii) Quantification of immunological processes, iii) Definition of observables to measure given an experimental objective, iv) reconciling disparate (or even conflicting) experimental results. .
    Type of Medium: Online Resource
    Pages: X, 298 p. 74 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030572044
    DDC: 571.96
    Language: English
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  • 85
    Keywords: Plant biotechnology. ; Biotechnology. ; Nanotechnology. ; Regenerative medicine. ; Plant Biotechnology. ; Biotechnology. ; Nanotechnology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Preface -- Nanomedicine: General Introduction from A to Z -- Immunology and Nanotechnology: Effects and Affects -- Role of Nanotechnology in Sensor Development -- Nanotechnology in the Characterization of Cancer -- Nano Vaccine -- Nanotechnology in Theranostics and In Vivo Imaging -- The Implication of Physical and Chemical Characterization of Therapeutic and Imaging Applications -- Polymers in Nanomedicine -- Delivery of Drug Payloads to Organs and Organ-Systems of Human Beings -- Drug Delivery Towards Cancer -- Drug Delivery Towards Malaria -- Nanotechnology in Tissue Engineering and Implant Development -- Interactions Between Nano-Delivery Agents and Immune Systems -- The Fate of Drug Delivery Agents after Delivery of Payload -- Index.
    Abstract: Nanomedicine is the field of science that deals with organic applications of medicine at the nanoscale level. It primarily addresses finding, anticipating, and treating sickness, as well as using nanotechnology to assist in controlling human frameworks at the cellular level. The nature of nanotechnology allows it to address numerous medical issues in humans. This book offers comprehensive information to better comprehend and apply multifunctional nanoparticles in nanomedicine, and thus open avenues in the field. Medicating at the nanolevel is an exceptional therapeutic avenue, as it avoids symptoms associated with conventional medicines. This book investigates recent insights into structuring novel drug delivery frameworks. It concentrates on the physical characteristics of drug delivery transporters, and the preliminary procedures involved in their use. The book offers in-depth detail that benefits academics and researchers alike, containing broad research from experts in the field, and serves as a guide for students and researchers in the field of nanomedicine, drug delivery, and nanotechnology.
    Type of Medium: Online Resource
    Pages: XIII, 265 p. 38 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030610210
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 631.52
    Language: English
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  • 86
    Keywords: Biotechnology. ; Regenerative medicine. ; Stem cells. ; Nanotechnology. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology. ; Nanotechnology.
    Description / Table of Contents: Module 1_Fundamentals of Biomaterials -- Module 2_Biomaterials in Tissue engineering -- Module 3_Applications of Biomaterials -- Module 4_Advances in Biomaterials.
    Abstract: This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.
    Type of Medium: Online Resource
    Pages: IX, 589 p. 88 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811600029
    DDC: 660.6
    Language: English
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  • 87
    Keywords: Biotechnology. ; Cytology. ; Nanobiotechnology. ; Biology. ; Nanotechnology. ; Nanomedicine. ; Biotechnology. ; Cell Biology. ; Nanobiotechnology. ; Biological Sciences. ; Nanotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Part 1. Cellular and molecular mechanisms in inflammatory diseases -- Chapter 1. Vascular Diseases as mediator of systemic inflammation -- Chapter 2. Inflammation and gut microbiote -- Chapter 3. Cardioimmunology: na interdisciplinar approach -- Chapter 4. Cell therapy as strategy for respiratory Diseases -- Chapter 5. Mitochondrial dysfunction as a trigger of inflammation in cardiovascular diseases -- Chapter 6. Cancer therapy-induced inflammation and its consequences -- Chapter 7. Coupling glucose phosphorylation to oxygen in brain mitochondria: would it be redox set point? -- Chapter 8. Methods for the analysis of arachidonic acid-derived metabolites in platelets -- Part 2. Nanomedicines for inflammatory diseases -- Chapter 9. In vitro models and molecular markers for assessing nano-based systems inflammatory potential -- Chapter 10. Using micro- and nanocarriers for myocardial targeted delivery -- Chapter 11. Nano-based hydrogels for atopic dermatitis treatment -- Chapter 12. Nanomedicine applied to inflammatory bowel diseases -- Chapter 13. Nanomedicine therapies for macrophage-targeted delivery -- Chapter 14. Nano-based therapies for pulmonary inflammatory diseases -- Chapter 15. Pulmonary inflammation treated by nanocarriers.
    Abstract: Biotechnology involves an interdisciplinary science that provides an interface between biological, molecular and cellular aspects of living organisms with broad technologies applicable in the fields of health, environment and materials. This book “Biotechnology applied to inflammatory diseases: Cellular mechanisms and nanomedicine” is focused on elaborating especially on two trendy areas from Biotechnology. In this volume, different inflammatory pathologies in terms of cellular and molecular mechanisms are characterized to better understand the science behind current precision medicine. The second part of the book focuses on the main biotechnological advancements for the understanding of the molecular mechanisms involved in the progression of various types of inflammatory diseases, highlighting up-to-date contributions of nanomedicine. The reader will be able to explore the utilization of technologies for various inflammatory diseases and will be able to enable an engaging and valuable knowledge for further research and clinically applied scenarios. .
    Type of Medium: Online Resource
    Pages: IX, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811983429
    Series Statement: Interdisciplinary Biotechnological Advances,
    DDC: 660.6
    Language: English
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  • 88
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Pharmacology. ; Nanotechnology. ; Nanochemistry. ; Pharmacology. ; Nanotechnology. ; Nanochemistry.
    Description / Table of Contents: Part 1 Introduction and Biomedical Applications of Nanoparticles -- 1. Introduction to Nanomaterials and Nanotechnology -- 2. Biomedical Applications of Nanoparticles -- Part II-Polymeric Nanoparticles -- 3. Nanocrystallization and Nanoprecipitation Technologies -- 4. Microfluidics Technology for Nanoparticles and Equipment-. 5. Production of Nanocomposites via Extrusion Techniques -- 6. The Use of Supercritical Fluids Technologies for Nanoparticle Production -- 7. Salting out and Ionic Gelation Manufacturing Techniques for Nanoparticles -- 8. Nanogel Synthesis by Irradiation of Aqueous Polymer Solutions -- 9. Cellulose acetate based nanofibers: Synthesis, Manufacturing and Applications -- 10. Production of nanofibers, environmental challenges and solutions -- Part III-Lipid Nanoparticles -- 11. High Pressure Homogenization Techniques for Nanoparticles -- 12. Solvent emulsification evaporation and solvent emulsification diffusion techniques for nanoparticles -- 13. Ultrasound Activated Nanoemulsions -- 14. Multiple Emulsions: Emphasizing on industrial applications -- 15. Membrane techniques for the preparation of nanomaterials -- 16. Self-assembling Lipid Nanoparticles/Nanosystems (SLNN) using Hydrophilic Solvents: Overview and Industrial Uses -- 17. Nanoemulsions – An emerging technology in drug delivery -- Part IV- Metallic Nanoparticles -- 18. Manufacturing techniques for carbon nanotubes, gold nanoparticles and silver nanoparticles -- 19. Radio frequency (RF) plasma-based Synthesis of metallic Nano particles for Biomedical Application -- 20. Techniques for accurate sizing of nanoparticles -- 21. Silver nanoparticles synthesis from cyanobacteria: Environmental and biomedical applications -- 22. Selenium Nanoparticles: Green Synthesis and Exploitation -- Part V- Quality control for nanoparticles -- 23. Practical guidelines for the characterization and quality control of nanoparticlesin the pharmaceutical industry -- Part VI-Challenges in scale-up production of nanoparticles -- 24. Nanomedicine Scale-Up Technologies: Feasibilities and Challenges -- 25. Patent survey on recent technology for nanoparticles -- Part VII-Injectable Nanosystems -- 26. Injectable Nanosystems and Inherent Nano-Serum Interactions -- Part VIII- Future directions and challenges -- 27. Current Challenges and Future Directions in Nanomedicine.
    Abstract: This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of Nanoparticles II. Polymeric Nanoparticles III. Lipid Nanoparticles IV. Metallic Nanoparticles V. Quality Control for Nanoparticles VI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and Challenges Leading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges. .
    Type of Medium: Online Resource
    Pages: XV, 611 p. 155 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030507039
    DDC: 615
    Language: English
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  • 89
    Keywords: Agriculture. ; Plant biotechnology. ; Refuse and refuse disposal. ; Nanotechnology. ; Agriculture. ; Plant Biotechnology. ; Waste Management/Waste Technology. ; Nanotechnology.
    Description / Table of Contents: Chapter 1 Switching to bioplastics for sustaining our environment -- Chapter 2 Bioenergy production from wastewater resources using Clostridium species -- Chapter 3 Management of Phosphate in Domestic Wastewater Treatment Plants -- Chapter 4 Agricultural Waste: A potential solution to combat heavy metal toxicity -- Chapter 5 Current Trends and Emerging Technologies for Pest Control Management of Rice (Oryza sativa) Plants -- Chapter 6 Comet assay: is it a sensitive tool in ecogenotoxicology? -- Chapter 7 Drosophila melanogaster as a model to study Acrylamide induced toxicity and the effects of phytochemicals -- Chapter 8 Mesoporous Silica Nanoparticles are Nanocarrier for Drug Loading and Induces Cell Death in Breast Cancer -- Chapter 9 Insights on the Biotechnological applications of Marine Fungal Exopolysaccharides.
    Abstract: This book reviews the production of bioplastic from various raw materials and recycling wastewater into useful bioproducts by bacteria. In addition, it also addresses the recent advancement in pest control in rice plants, different methods to analyse genotoxicity on soil samples and the effect of phytocompounds on acrylamide-induced toxicity in Drosophilla. Interestingly, this book also discusses mesoporous silica nanoparticles' role as nanocarrier material for inhibiting the cancer cell, especially breast cancer and various biotechnological applications of marine fungal exopolysaccharides.
    Type of Medium: Online Resource
    Pages: XI, 261 p. 54 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030777951
    Series Statement: Environmental Chemistry for a Sustainable World, 68
    DDC: 630
    Language: English
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  • 90
    Keywords: Bioinformatics. ; Life sciences. ; Bioinformatics. ; Life Sciences. ; Bioinformatics.
    Description / Table of Contents: The new omics era into systems approaches: what is the importance of separation techniques? -- Biological Applications for LC-MS-Based Proteomics -- The role of chromatographic and electromigration techniques in Foodomics -- CE-MS for proteomics and intact protein analysis -- Peptidomics and Capillary Electrophoresis -- Discovery of native protein complexes by liquid chromatography followed by quantitative mass spectrometry -- Capillary electrophoresis based N-Glycosylation analysis in the biomedical and biopharmaceutical fields -- Practical considerations in method development for gas chromatography-based metabolomic profiling -- Capillary electrophoresis-mass spectrometry for metabolomics: possibilities and perspectives -- Liquid Chromatography – Mass Spectrometry for Clinical Metabolomics: An Overview -- Analytical platforms for mass spectrometry-based metabolomics of polar and ionizable metabolites -- Metabolomic data treatment: basic directions of the full process -- Index.
    Abstract: This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses and unique aspects in each case. This volume intends to offer wide ranging options available to researchers on omics sciences, and how to integrate them in order to achieve the comprehension of a biological system as a whole. Omic sciences have been of ultimate importance to comprehend the complex biochemical reactions and related events that occurs upon a biological system. The classical central dogma of molecular biology, which states that genetic information flows unidirectionally from DNA to RNA and then to proteins, has been gradually replaced by the systems biology approach. This book presents a multidisciplinary approach that explains the biological system as a whole, where the entire organism is influenced by a variety of internal events as well as by the environment, showing that each level of the biological information flux may influence the previous or the subsequent one. .
    Type of Medium: Online Resource
    Pages: XII, 273 p. 74 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030772529
    Series Statement: Proteomics, Metabolomics, Interactomics and Systems Biology, 1336
    DDC: 570.285
    Language: English
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  • 91
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical genetics. ; Neurosciences. ; Bioinformatics. ; Medical Genetics. ; Neuroscience. ; Computational and Systems Biology.
    Description / Table of Contents: 1-Stratification of patients with Chronic Obstructive Pulmonary Disease using Volatile Organic Compounds -- 2-Evidence-based Leadership: A Study of its Application to General Hospital of the Public Health System through the Implementation Leadership Scale -- 3-Greek nurses’ perception of hospital ethical climate. A cross-sectional study -- 4-Investigating the main causes of conflicts and the managements strategies are used by healthcare professionals. The case of general hospital of Arta -- 5-Incidence of deep vein thrombosis and its effect on health related quality of life among nurses of Greek public hospital. A multicenter study -- 6-Factors affecting anxiety and depression in caregivers of hemodialysis patients -- 7-Hand grip strength in patients on hemodialysis: An observational study -- 8-The effect of spirituality on illness perceptions in patients undergoing hemodialysis -- 9-Validation of the STOP-Bang Questionnaire in Greek patients suffering from obstructive sleep apnea -- 10-The role of Pythagorean Self-Awareness Intervention in obstructive sleep apnea. A randomized controlled trial -- 11-Tissue characterization in Cardiology. Moving beyond function -- 12-Psychiatric care in acute care units with locked doors: Nursing care providers’ perceptions and experiences -- 13-Researching nursing students’ attitudes towards mental health practice: cultural adaptation and validation of the Greek version of the Acceptability of Locking the Door Questionnaire in acute psychiatric care -- 14-Compliance of bronchial asthma patients' with the Mediterranean diet -- 15-Nurses’ experiences of psychiatric care in acute care units with an open door policy -- 16-Validation of the Greek Version of Hedonic, Eudaimonic and Extrinsic Motives for Activities (HEEMA) Instrument -- 17-Event-Related Rumination Inventory: A Validation Process in the Greek Language -- 18-The job rotation of nursing staff and its effects on nurse`s satisfaction and occupational engagement -- 19-The burden on carers with multiple sclerosis -- 20-Attitudes of the general population regarding patient information for a chronic and life-threatening disease. A cross-sectional study -- 21-Assessment of healthcare professionals’ knowledge and awareness on aspects related to ionizing radiation examinations in Athens, Greece -- 22-Medication errors and their correlation with nurse's satisfaction. The case of the hospitals of Lasithi, Crete -- 23-Health-Related Quality of Life and Living Costs of HIV-Infected Patients -- 24-Evaluation of anxiety and depression in women undergoing mastectomy in Greece -- 25-The effect of emotional intelligence on caring behaviors among psychiatric nurses in Greece -- 26-Investigating nursing leadership in intensive care units of hospitals of Northern Greece and its relationship to the working environment -- 27-Health-Related Quality of Life and Rehabilitation Costs of Patients with Amputated Limb -- 28-Anxiety and depression in hemodialysis: Sex differences -- 29-Patient knowledge, adherence to the therapeutic regimen, and quality of life in hemodialysis -- 30-The burden of caregivers of patients after hip replacement and its impact on the cost of living of the family -- 31-The effects of exercise in patients with Sarcopenia -- 32-Fluid dynamics derived parameters in coronary vessels -- 33-Level of knowledge about COPD among patients and caregivers -- 34-Increased body mass index (BMI) and sunscreen use are associated with inadequate vitamin D status in Greek adults in winter -- 35-The effect of whole-body cryostimulation in healthy adults -- 36-Exhaled Nitric Oxide (FeNO) in patients hospitalized for an exacerbation of bronchiectasis and/or COPD -- 37-Formulation and Evaluation of Dermatological product containing Niacinamide -- 38-Exhaled breath condensate and dyspnea in COPD -- 39-The Effects of Pythagorean Self-Awareness Intervention on Irritable Bowel Syndrome Patients: A Non-Randomized Controlled Trial -- 40-Adults’ stress response to unexpected oral and arithmetic tasks in supine position -- 41-Triangles and family engagement in drug and alcohol addiction treatment -- 42-Use of fortified bread for addressing vitamin D deficiency. .
    Abstract: The 5th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2022) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. This volume focuses on the sessions from the conference on Molecular Biology, Chemical Biology, and Cellular Biology.
    Type of Medium: Online Resource
    Pages: XVIII, 319 p. 137 illus., 132 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031319785
    Series Statement: Advances in Experimental Medicine and Biology, 1423
    DDC: 616.042
    Language: English
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  • 92
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biomedical engineering. ; Bioinformatics. ; Epidemiology. ; Mathematical models. ; Biomedical Engineering and Bioengineering. ; Computational and Systems Biology. ; Epidemiology. ; Mathematical Modeling and Industrial Mathematics.
    Description / Table of Contents: table of contents -- introduction -- infectious diseases -- a brief history of infectious diseases -- II. mathematical epidemiology -- introduction to compartment modeling -- compartment modeling of epidemiology -- concepts of endemic disease modeling -- data-driven modeling in epidemiology. - compartment modeling of COVID19 -- early outbreak dynamics of COVID-19 -- asymptomatic transmission of COVID-19 -- inferring outbreak dynamics of COVID-19 -- modeling outbreak control -- managing infectious diseases -- change-point modeling of COVID-19 -- dynamic compartment modeling of COVID-19 -- network modeling of epidemiology -- network modeling of epidemic processes -- network modeling of COVID-19 -- dynamic network modeling of COVID-19 -- informing political decision making through modeling -- exit strategies from lockdown -- vaccination strategies -- the second wave -- lessons learned.
    Abstract: This innovative textbook brings together modern concepts in mathematical epidemiology, computational modeling, physics-based simulation, data science, and machine learning to understand one of the most significant problems of our current time, the outbreak dynamics and outbreak control of COVID-19. It teaches the relevant tools to model and simulate nonlinear dynamic systems in view of a global pandemic that is acutely relevant to human health. If you are a student, educator, basic scientist, or medical researcher in the natural or social sciences, or someone passionate about big data and human health: This book is for you! It serves as a textbook for undergraduates and graduate students, and a monograph for researchers and scientists. It can be used in the mathematical life sciences suitable for courses in applied mathematics, biomedical engineering, biostatistics, computer science, data science, epidemiology, health sciences, machine learning, mathematical biology, numerical methods, and probabilistic programming. This book is a personal reflection on the role of data-driven modeling during the COVID-19 pandemic, motivated by the curiosity to understand it.
    Type of Medium: Online Resource
    Pages: XVI, 312 p. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030828905
    DDC: 610.28
    Language: English
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  • 93
    Keywords: Food Microbiology. ; Food science. ; Nanotechnology. ; Food Microbiology. ; Food Science. ; Food Nanotechnology.
    Description / Table of Contents: Chapter 1_Introduction to Nanobiosensing technologies and bioanalytical systems -- Chapter 2_Nanobiosensing for Food Safety -- Chapter 3_Biosensors in Food Processing, Safety, and Quality Controlin Food Engineering -- Chapter 4_MIcrofluidic technology for the Evaluation of Natural Toxins -- Chapter 5_Printed Chip-based technology for real-time assessments of food adulterents -- Chapter 6_Optoelectronic systems for Antioxidant in Foods and Beverages -- Chapter 7_Multiplexing nanoengineered technology in food-industries -- Chapter 8_Translational Bioanalytical Techniques in Food Science and Technology -- Chapter 9_Electronic noses and tongues in Food Science -- Chapter 10_Application of Nanotechnology in Food Ananlysis -- Chapter 11_Molecular techniques in detection of Foodborne pathogens -- Chapter 12_Molecular techniques for GMO and Transgenic Foods -- Chapter 13_Aptamer based miniaturized technology for drug analysis. -- Chapter 14_Advanced techniques for detection of food adulterations and allergens -- Chapter 15_Industrial technologies for food quality control.
    Abstract: This book reviews applications of nanomaterial and nanodevices in the food industry. It also discusses the advanced bioanalytical techniques, including Enzyme-Linked Immunosorbent Assay (ELISA), immunoanalytical techniques, monoclonal antibody-based immunological techniques for detecting food adulterations and allergens. It comprehensively covers electrode modification and nano-engineered fabrication of biosensors to enhance their functionalities for utilization in food industries. The book highlights the utilization of nanobiosensors for food safety and quality analysis, such as detection of toxin, food-borne pathogen, allergen, and evaluation of toxicity. Further, it also summarizes the recent advances in nanodevices such as nano-systems, nano-emulsions, nanopesticide, nanocapsule and their applications in the food industry. Lastly, it covers nanomaterial-based sensors for drug analysis in diverse matrices. It serves as an invaluable source of information for professionals, researchers, academicians, and students related to food science and technology.
    Type of Medium: Online Resource
    Pages: X, 438 p. 104 illus., 98 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811670299
    DDC: 664.001579
    Language: English
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  • 94
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Biophysics. ; Biomathematics. ; Biotechnology. ; Biomedical engineering. ; Bioinformatics. ; Computational and Systems Biology. ; Biophysics. ; Mathematical and Computational Biology. ; Biotechnology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: 1-Digging for Significant Genes in Microarray Expression Data Based on Systematic Sampling and Hierarchal Clustering Algorithm -- 2-A DSS for predicting Lymphoma in primary Sjogren’s Syndrome patients -- 3-Decision Support System for Breast Cancer Detection Using Biomarker Indicators -- 4-Hepatocellular Carcinoma Detection Using Machine Learning Techniques -- 5-Web-based Decision Support System for Coronary Heart Disease Diagnosis -- 6-A Decision Support System for the Prediction of Drug Predisposition through Personality Traits -- 7-Development of a diagnostic tool for balance disorders based on machine learning techniques -- 8-Systems Approaches in the Common Metabolomics in Acute Lymphoblastic Leukemia and Rhabdomyosarcoma Cells: A Computational Approach -- 9-Bioinformatics Analyses of Spatial Peripheral Circadian Clock-Mediated Gene Expression of lucocorticoid Receptor-related Genes -- 10-Machine Learning for Autistic Spectrum Disorder Risk Screening -- 11-Mobile Application for Monitoring and Preventing Cognitive Decline through Lifestyle Intervention -- 12-Virtual Reality Zoo Therapy for Alzheimer’s Disease Using Real-time Gesture Recognition -- 13-Validation of the Greek Version of Social Media Disorder Scale -- 14-Adiponectin and its Effects on Acute Leukemia Cells: An Experimental and Bioinformatics Approach -- 15-Nature and quantum inspired procedures - a short literature review -- 16-Handling the cellular complex systems in Alzheimer’s disease through a graph mining approach -- 17-Debunking the neuromyth of learning style -- 18-Expert characteristics: implications for expert systems -- 19-Improving the Run-Time of Space E cient n-gram Data Structures using Apache Spark -- 20-Development of a protein biochip platform for Parkinson’s disease -- 21-The Cultural adaptation of the iSupportDementia in Greece -- 22-The use of data collection and big data analysis in Neurodegenerative disease prevention -- 23-Fractal Dynamics in the RR Interval of Craniopharyngioma and Adrenal Tumor in Adolescence -- 24-Bioinformatics approaches for Parkinson’s disease in clinical practice: Data- driven biomarkers and pharmacological treatment -- 25-Emerging Machine Learning techniques for modelling cellular complex systems in Alzheimer’s disease -- 26-Cognitive Enhancement Through Mathematical Problem Solving -- 27-Cognitive tasks of an information system for memory training and cognitive enhancement using mobile devices -- 28-An application for exploring visual perception. A pilot neuroeducational study -- 29-Genes Classification Based on Multi Class SVMs with Systematic Sampling and Hierarchical Clustering (SSHC) Algorithm -- 30-Multinetwork motor learning as a model for dance in neurorehabilitation -- 31-Controlling the chimera form in the Leaky Integrate-and-Fire model -- 32-Qualitative differences between the Semi-separable and the “Almansi type” Stokes stream function expansions in the study of biological fluids -- 33-A multiscale mathematical model for tumor growth, incorporating the GLUT1 expression.
    Abstract: The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. Computational methodologies for implementation on the discovery of biomarkers for neurodegenerative diseases are extensively discussed. This volume focuses on the sessions from the conference regarding computational biology and bioinformatics.
    Type of Medium: Online Resource
    Pages: XV, 288 p. 105 illus., 92 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030787752
    Series Statement: Advances in Experimental Medicine and Biology, 1338
    DDC: 570.285
    Language: English
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  • 95
    Keywords: Agriculture. ; Plant diseases. ; Nanotechnology. ; Food Microbiology. ; Pollution. ; Agriculture. ; Plant Pathology. ; Nanotechnology. ; Food Microbiology. ; Pollution.
    Description / Table of Contents: Preface -- 1 Nanoparticles from Fungal Resources: Importance and Applications -- 2 Nanoparticles Incorporated Soy Protein Isolate Films -- 3 Formulation, Characterization, and Potential Application of Nanoemulsions in Food and Medicine -- 5 Advances in Agronanotechnology and Future Prospects -- 6 Nanobiotechnology and Its Application in Agriculture and Food Production -- 7 Application of Nanotechnology for Sustainable Crop Production Systems -- 8 Nanoparticles from Endophytic Fungi and Their Efficacy in Biological Control -- 9 Application of Nanotechnology in Polyphagous Destructive Insect Pest Management of Agricultural Crops -- 10 Myconanoparticles as Potential Pest Control Agents -- 11 Nanoparticles and Their Role in Bioenergy Production -- 12 Remediation of Heavy Metal Ions using Nanomaterials Sourced from Wastewaters -- 13 Application of Nanotechnology in the Bioremediation of Heavy metals and Wastewater Management -- 14 Biogenic Nanoparticles for Degradation of Noxious Dyes -- 15 Ecotoxicity of Nanomaterials in Aquatic Environment -- 16 Impact of Nanomaterials on Beneficial Insects in Agricultural Ecosystem -- Index.
    Abstract: Nanotechnology progresses its concerts and suitability by improving its effectiveness, security and also reducing the impact and risk. Various chapters in this book are written by eminent scientists and prominent researchers in the field of nanotechnology across the world. This book is focused to put emerging techniques forward using nanoparticles for safe and nutritional food production, protecting crops from pests, increasing nutritional value and providing solutions for various environmental issues. The outcome of this book creates a path for wide usage of nanoparticles in food, agriculture and the environment fields. This book has clear and simple illustrations, tables and case studies to understand the content even by non-experts. This book especially deals with the nanotechnology for controlling plant pathogens, food packaging and preservation, agricultural productivity, waste water treatment and bioenergy production. Hence, this book can be adopted and used by many researchers and academicians in the fields of food, agriculture, environment and nanotechnology for catering the needs of sustainable future. The salient features of this book are • Describes nanotechnology as an interdisciplinary and emerging field in life sciences • Useful for researchers in the cutting edge life science related fields of nanoscience, nanobiology and nanotechnology • Deal with various problems in food, agriculture and environmental sector for sustainable solutions through the application of nanotechnology • Supported with illustrations in color, tables and case studies (wherever applicable), and • Contributed and well written by nanotechnology experts from across various disciplines.
    Type of Medium: Online Resource
    Pages: XVI, 405 p. 74 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030319380
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 630
    Language: English
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  • 96
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Bioinformatics. ; Cytology. ; Medicine Research. ; Biology Research. ; Computational and Systems Biology. ; Cell Biology. ; Biomedical Research. ; Bioinformatics.
    Description / Table of Contents: Chapter 1: The Structure And Function Of Living Organisms -- Chapter 2: Energy In Biology – Demand And Use -- Chapter 3: Information – Its Role And Meaning In Organism -- Chapter 4: Regulation In Biological Systems -- Chapter 5: Interrelationship In Organized Biological Systems. .
    Abstract: This open-access textbook is an excellent introduction to systems biology, which has developed rapidly in recent years. It discusses the processes in living organisms in an integrated way, enabling the reader to understand the fundamental principles and cause-effect relationships in biology and biochemistry. The authors have chosen an original but at the same time clear way of presenting the topics, repeatedly drawing comparisons and models from the macroscopic world and making the reader aware of the unity of the laws of physics, chemistry and biology. The fully updated 2nd edition also contains information that has only become available as a result of the increase in knowledge in recent years. This includes information on tumorigenesis, where significant progress has been made due to the explosive development of genetic knowledge as well as bioengineering with a highly effective technique adopted from the solutions of the bacterial world, such as CRISPR/CAS. This richly illustrated book is essential for postgraduate students and scientists of the following disciplines: biology, biotechnology, medicine, bioinformatics, robotics and automation, biocybernetics, and biomedical engineering. It is also an exciting read for anyone interested in biology.
    Type of Medium: Online Resource
    Pages: XVII, 257 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031315572
    DDC: 570.285
    Language: English
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  • 97
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Medicine Research. ; Biology Research. ; Bioinformatics. ; Sports sciences. ; Medical informatics. ; Biomedical Research. ; Bioinformatics. ; Sport Science. ; Health Informatics.
    Description / Table of Contents: Chapter 1. Ontologies and Knowledge Graphs for Exercise Medicine -- Chapter 2. Participatory exercise medicine and personalized healthcare -- Chapter 3. Integration of genetic and phenotyping data for sports medicine -- Chapter 4. Microbiota, sports and exercise medicine -- Chapter 5. Human immune system and exercise medicine: current process and future directions -- Chapter 6. Circadian Rhythm and Personalized Exercise -- Chapter 7. Data-driven Exercise Medicine for Cardiovascular Disease -- Chapter 8. Physical Activities and Prevention of Neurodegenerative Diseases -- Chapter 9. Exercise guidelines for cancer patients -- Chapter 10. Diabetes as a metabolic disease and translational exercise medicine informatics.
    Abstract: The book provides readers the informatics and data-driven models for the discovery of personalized excise prescriptions applied to different cases. Overdiagnosis or over-treatment often happened since the complex interaction among the lifestyle, genetic, and environmental factors. Sports and exercise are reported efficient to prevent or reduce the risk of diseases, but the interactions between sports/exercise and disease are personalized and complex. Translational informatics is a powerful paradigm and it promotes the transfer of big data, knowledge and models to the precision application of sports to prevent diseases. Sports and exercise may have different effects on diverse diseases including cancers, neurodegenerative disease, and cardiovascular diseases, etc. This book covers many modern informatics models such as ontologies, knowledge graphs, blockchain, participatory medicine, semantic artificial intelligence, big data modeling, and so on. It also describes the challenges for the sports and exercise medical data sharing and standardization, the privacy protection of data as well as the integration of data from genomic level to physiological phenotype level. This book will be helpful to the readers who are interesting in sports and exercise medicine, healthcare, big data modeling, artificial intelligence in medicine and healthcare. .
    Type of Medium: Online Resource
    Pages: IX, 234 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811691621
    DDC: 610.72
    Language: English
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  • 98
    Keywords: Plant anatomy. ; Nanotechnology. ; Plants Development. ; Plant biotechnology. ; Plant Anatomy and Morphology. ; Nanotechnology. ; Plant Development. ; Plant Biotechnology.
    Description / Table of Contents: Preface -- Global Importance and Cycling of Nanoparticles -- Environmental Emissions of Nanoparticles -- Bio- and Geo-Transformation and Bioavailability of Nanoparticles -- Interaction of Nanoparticles to Soil Pollutants -- Impact of Nanoparticles to Soil Systems -- Too Much or Too Little? A Review of the Connundrum of Nanoparticles -- Application and Use of Nanoelements in Combating Plant Nutrition -- Role of Nanoparticles in Remediation of Contaminated Soils -- Biochemical, Molecular and Ultrastructural Aspects in Phytoremediation of Nanoparticles Subjected to Unfertilized Soil -- Nanomaterials: A New Approach in Biofortification -- Applications and Implications of Nano-Fertilizers in Food Industries -- Nanobiosensors Based on Agri-Biomass -- Nanoparticles Uptake and Translocation in Plants -- Risks and Concerns of Use of Nanoparticles in Agriculture -- Mechanism of Nanoparticles Mediated Alleviating Biotic and Abiotic Stresses in Agricultural Crops -- Role of Nanoparticles in Environment, Human, and Animals Under Contaminated Soil -- Cytotoxic and Genotoxic Aspects of nanoparticles Interactions with Plant Systems -- Nanoparticles and its Effects on Growth, Yield, and Crop Quality Cultivated Under Polluted Soil -- Impact of nanoparticles of Modulations of Genes and Secondary Metabolites in Plants -- Interaction of Nanoparticles with Plant Growth Promoting Rhizobacteria in Polluted Soil -- Interaction of Nanomaterials with Plant Metabolism -- Bibliography -- Index.
    Abstract: NNanotechnology has shown great potential in all spheres of life. With the increasing pressure to meet the food demands of rapidly increasing population, thus, novel innovation and research are required in agriculture. The principles of nanotechnology can be implemented to meet the challenges faced by agricultural demands. Major challenges include the loss of nutrients in the soil and nutrient-deficient plants, which result in a lower crop yield and quality. Subsequently, consumption of such crops leads to malnourishment in humans, especially in underprivileged and rural populations. One convenient approach to tackle nutrient deficiency in plants is via the use of fertilizers; however, this method suffers from lower uptake efficiency in plants. Another approach to combat nutrient deficiency in humans is via the use of supplements and diet modifications; however, these approaches are less affordably viable in economically challenged communities and in rural areas. Therefore, the use of nano-fertilizers to combat this problem holds the greatest potential. Additionally, nanotechnology can be used to meet other challenges in agriculture including enhancing crop yield, protection from insect pests and animals, and by use of nano-pesticides and nano-biosensors to carry out the remediation of polluted soils. The future use of nanomaterials in soil ecosystems will be influenced by their capability to interact with soil constituents and the route of nanoparticles into the environment includes both natural and anthropogenic sources. The last decade has provided increasing research on the impact and use of nanoparticles in plants, animals, microbes, and soils, and yet these studies often lacked data involving the impact of nanoparticles on biotic and abiotic stress factors. This book provides significant recent research on the use of nano-fertilizers, which can have a major impact on components of an ecosystem. This work should provide a basis to further study these potential key areas in order to achieve sustainable and safe application of nanoparticles in agriculture.
    Type of Medium: Online Resource
    Pages: XI, 394 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030973896
    Series Statement: Sustainable Plant Nutrition in a Changing World,
    DDC: 571.32
    Language: English
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  • 99
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Synthetic Biology. ; Bioinformatics. ; Drug delivery systems. ; Industrial microbiology. ; Synthetic Biology. ; Bioinformatics. ; Drug Delivery. ; Industrial Microbiology.
    Description / Table of Contents: Chapter 1. Actinomycetes: Microbiology to Systems Biology -- Chapter 2. Diversity of actinobacteria in various habitats -- Chapter 3. Traditional Screening and Genome Guided Screening of Natural Products from Actinobacteria -- Chapter 4. The relationship between actinobacteria and rice -- Chapter 5.Non-ribosomally and ribosomally synthesized bioactive peptides – NRPS and RiPPs from actinobacteria -- Chapter 6. Genome Data Mining, Chemistry and Bioactivity of Sesquiterpenes from Actinobacteria -- Chapter 7. Genome Data Mining, Chemistry and Bioactivity of Sesquiterpenes from Actinobacteria -- Chapter 8. Cloning and Heterologous expression of Natural products from Actinobacteria -- Chapter 9. Synthetic Biology and Metabolic Engineering in Actinobacteria for Natural Product Production -- Chapter 10. CRISPR ERA: CURRENT APPLICATIONS AND FUTURE PERSPECTIVES ON ACTINOBACTERIA -- Chapter 11. Uncultured Actinobacteria and Reverse engineering and Artificial Intelligence role in future -- Chapter 12. Cultivation and Diversity of Marine Actinomycetes: Molecular Approaches and Bioinformatics Tools -- Chapter 13. Antimicrobial Potential and Metabolite Profiling of Marine Actinobacteria -- Chapter 14. Pharmacology of FDA Approved Medicines from Actinobacteria.
    Abstract: This book summarizes the basics of actinobacteria, from microbiology to synthetic biology. It focuses on diversity, NRPS, sesquiterpenes, lantipeptide, bioinformatics apparatuses, cloning, CRISPR, reverse engineering, FDA supported medications, and marine actinobacteria. It also covers the latest trends in drug discovery from actinobacteria, and introduces several recently developed bioinformatics and synthetic biology tools to explore new antibiotics from actinobacteria. Many natural products such as polyketides, isoprenoids, phenazines, peptides, indolocarbarbazoles, sterols, and others have been isolated and characterized from actinobacteria. Some products are synthesized by the non-ribosomal peptide synthetases (NRPSs), polyketide synthases (PKSs), or other functional genes. Although genome sequencing has uncovered the differing qualities of these chemicals, recognizing new items and their biosynthetic pathways is still under examination. Cryptic metabolic pathways have been explored using molecular techniques or culture-dependent approaches. In recent years, researchers’ primary interest is to identify the specific conditions or agents that wake the cryptic antibiotics. Several bioinformatics and synthetic biology tools were developed to explore new antibiotics from actinobacteria. The book comprises 14 chapters with different aspects of application and utilization of actinomycetes from the microbiology; systems biology, pharmacology of natural products, bioinformatics, actinomycete and its diversity, CRISPR, artificial Intelligence, synthetic biology, metabolic engineering, expressional studies, and biosynthetic gene clusters. The book delivers useful information on actinomyces to researchers, novices in genome designing, specialists, clinicians, policymakers, and professionals.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811658358
    DDC: 570.724
    Language: English
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  • 100
    Keywords: Neurosciences. ; Neural circuitry. ; Bioinformatics. ; Computer science. ; Neuroscience. ; Neural Circuits. ; Computational and Systems Biology. ; Computer Science.
    Description / Table of Contents: PART I. Cellular Scale -- Chapter 1. Modelling Neurons in 3D at the Nanoscale -- Chapter 2. Modelling Dendrites and Spatially-Distributed Neuronal Membrane Properties -- Chapter 3. A User's Guide to Generalized Integrate-and-Fire Models -- Chapter 4. Neuron-glia Interactions and Brain Circuits -- Chapter 5. Short-term Synaptic Plasticity: Microscopic Modelling and (some) Computational Implications -- PART II. Molecular Scale -- Chapter 6. The Mean Field Approach for Populations of Spiking Neurons -- Chapter 7. Multidimensional Dynamical Systems with Noise -- Chapter 8. Computing Extracellular Electric Potentials from Neuronal Simulations -- Chapter 9. Bringing Anatomical Information into Neuronal Network Models -- PART III. Network Scale -- Chapter 10. Computational Concepts for Reconstructing and Simulating Brain Tissue -- Chapter 11. Reconstruction of the Hippocampus -- Chapter 12. Challenges for Place and Grid Cell Models -- Chapter 13. Whole-Brain Modelling: Past, Present, and Future.
    Abstract: This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. .
    Type of Medium: Online Resource
    Pages: XII, 359 p. 115 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030894399
    Series Statement: Cellular Neuroscience, Neural Circuits and Systems Neuroscience, 1359
    DDC: 612.8
    Language: English
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