ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Books  (41)
  • Maps
  • Drug delivery systems.
Collection
  • Books  (41)
  • Maps
Source
Keywords
Publisher
Language
Years
DDC
  • 1
    Online Resource
    Online Resource
    Malarial Drug Delivery Systems : Advances in Treatment of Infectious Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Nanobiotechnology. ; Pharmaceutical chemistry. ; Tropical medicine. ; Pharmacology. ; Medical microbiology. ; Drug Delivery. ; Nanobiotechnology. ; Pharmaceutics. ; Tropical Medicine. ; Pharmacology. ; Medical Microbiology.
    Description / Table of Contents: Malaria: Cellular Understanding of Disease -- Drug Resistance, Statistics and Patent Status -- Malaria: Current Treatment Options -- Polymeric Nanoparticles in Malaria -- Solid Lipid Nanoparticles in Malaria -- Dendrimers in Malaria -- Liposomes in Malaria -- Micro and Nano Emulsions in Malaria -- Nanosuspension in Malaria -- Alginate and Gelatin Nanoparticles in Malaria -- Niosomes in Malaria -- Metal Nanoparticles in Malaria -- Nanotechnology in Malaria Diagnosis -- Nanotechnology-based Vaccination -- Herbal Platforms in Malaria -- Surface-modified Drug Delivery Systems in Malaria,- Clinical Trials in Malaria -- Malaria-Overall Picture -- New Drugs in Synthesis Research for Malaria -- Disease Models In Malaria Research.
    Abstract: The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause of significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the micro-organisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, infectious diseases will undoubtedly persist as permanent and main threats to humanity for now and in the future, primarily due to increased longevity that almost always comes at the cost of impaired immunity. A total of four books are covered under the series of Infectious drug diseases. - Malarial drug delivery systems - Tubercular drug delivery systems - Viral drug delivery systems - Infectious disease drug delivery systems The theme of the first book is Malaria. This book compiles the complete road map of malarial drug delivery systems by understanding the pathophysiology of the disease, the current state of malaria across the globe, new clinical trials, emerging drugs, and the development of novel drug delivery platforms. Various novel micro-and nano-formulations using promising technologies are being explored to deliver the malarial drug via different administration routes. This book addresses the gap between new approaches and old treatment modalities and how the former is superior in pharmacological performance when tested in in-vitro and in-vivo. Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of malarial research.
    Type of Medium: Online Resource
    Pages: X, 395 p. 55 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031158483
    URL: https://doi.org/10.1007/978-3-031-15848-3
    DOI: 10.1007/978-3-031-15848-3
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 2
    Online Resource
    Online Resource
    Deciphering Drug Targets for Alzheimer’s Disease (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biology. ; Neurosciences. ; Biotechnology. ; Drug delivery systems. ; Biomedical Research. ; Biological Sciences. ; Neuroscience. ; Biotechnology. ; Drug Delivery.
    Description / Table of Contents: Chapter 1.Deciphering New Drug Targets in Alzheimer’s Disease -- Chapter 2. Novel Therapeutic Targets for Treating Alzheimer’s Disease -- Chapter 3. Modified Investigation Tools and Techniques Useful in Alzheimer’s Disease Research -- Chapter 4. Dual Specificity Tyrosine Phosphorylation Regulated Kinase1A (DYRK1A) Inhibitors: The Quest for a Disease-Modifying Treatment for Alzheimer’s Disease -- Chapter 5. β-secretase as a primary drug target of Alzheimer disease: Function, Structure, and Inhibition -- Chapter 6. Endocrine Receptors: The Potential Therapeutic Targets for Alzheimer’s -- Chapter 7. Calcium Channels as a Potential Therapeutic Target for Alzheimer’s Disease -- Chapter 8. Traversing Through the Trajectory of Pathogenic Astrocytes in Alzheimer’s Disease -- Chapter 9. Targeting Mitochondrial Dynamics as a Restorative Approach in the Treatment of Alzheimer’s Disease -- Chapter 10. Epigenetic Therapy for Alzheimer’s Disease -- Chapter 11. Exploring the Diverse Roles of GSK-3ß Kinase in Alzheimer’s Disease -- Chapter 12. Role of Target Fishing in Discovery of Novel Anti-Alzheimer’s Agents: In Silico Applications -- Chapter 13. Multi-Target Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery -- Chapter 14. Investigating the Role of Tau Proteins in Alzheimer’s Disease-From Typical Functioning MAPs to Aberrant Fibrillary Deposits in the Brain -- Chapter 15. The Overview of Drugs Used in Alzheimer’s Disease and Their Molecular Targets.
    Abstract: This book explains the fundamental characteristics and biofunctionality of Alzheimer’s Disease drug targets and provides up-to-date information on the full range of their biomedical applications. An introductory section gives an overview of the recent developments related to drug targets identified and studied related to Alzheimer’s Disease and key developments from preclinical and clinical studies focusing on various molecular targets related to AD and dementia by subject experts all around the globe. Here, individual chapters address the progress and perspectives in human and non-human research, role of various biomarkers as an overview, advanced gene therapy, and novel compounds for therapeutic targets for Alzheimer’s disease. The book will be essential reading for graduate students, scientists, and engineers in any of the biomedical research fields in which efforts are being made to utilize novel drug targets and develop effective strategies for new drug targeting and delivery in Alzheimer’s disease treatment.
    Type of Medium: Online Resource
    Pages: XV, 381 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819926572
    URL: https://doi.org/10.1007/978-981-99-2657-2
    DOI: 10.1007/978-981-99-2657-2
    DDC: 610.72
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 3
    Online Resource
    Online Resource
    Tubercular Drug Delivery Systems : Advances in Treatment of Infectious Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Diseases. ; Pharmaceutical chemistry. ; Nanomedicine. ; Drug Delivery. ; Diseases. ; Pharmaceutics. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Global health and Tuberculosis past, present and Future -- Tuberculosis: cellular understanding of disease.-Metal nanoparticles in TB -- TB: current treatment options -- Polymeric nanoparticles in TB -- Solid lipid nanoparticles in TB -- Dendrimers in TB -- Liposomes in TB -- Micro, nano emulsions in TB -- Nano suspension in TB -- Alginate, gelatin nanoparticles in TB -- Niosome in TB -- Surface modified drug delivery systems in TB -- Clinical trials in TB -- Herbal platforms in TB.
    Abstract: The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the microorganisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, the infectious diseases will undoubtedly persist as permanent and main threats to humanity now and in the future, primarily due to increased longevity that almost always comes at a cost of impaired immunity. A total of four books are covered under the series of Infectious diseases. • Malarial drug delivery systems • Tubercular drug delivery systems • Viral drug delivery systems • Infectious disease drug delivery systems The theme of the second book is Tuberculosis (TB). This book addresses the recent trends in drug delivery for treating TB using new formulation technologies, and the mechanism how it can prevent or delay the drug resistance. It covers current drug therapy and new drug targeting approaches focusing on innovative trend-defining technologies and drug delivery platforms. It is essential to understand the relationship between host pathogens for better treatment. Various novel and nano-formulations using promising technologies are being explored to deliver TB drugs via different administration routes at right pathological site. This book addresses the gap between new and old treatment TB modalities and how they are superior in pharmacological performance when tested in in-vitro and in-vivo. Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of TB research.
    Type of Medium: Online Resource
    Pages: X, 337 p. 51 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031141003
    URL: https://doi.org/10.1007/978-3-031-14100-3
    DOI: 10.1007/978-3-031-14100-3
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 4
    Online Resource
    Online Resource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 5
    Online Resource
    Online Resource
    Biomaterials and Biopolymers (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmaceutical chemistry. ; Biomaterials. ; Pharmacology. ; Drug delivery systems. ; Vaccines Biotechnology. ; Pharmaceutics. ; Biomaterials. ; Pharmacology. ; Drug Delivery. ; Biomaterials-Vaccines.
    Description / Table of Contents: Introduction to Biomaterials -- Biodegradable Polymers -- Natural and semi-natural polymers -- Fundamentals and Biomedical Applications of Smart Hydrogels -- Engineering biomaterials for nucleic acid-based therapies -- Mechanics of Biomaterials for Regenerative Medicine -- Biomaterials for controlled drug delivery applications -- BIOMATERIALS APPLICATION: IMPLANTS -- Living Biomaterials -- Therapeutic Polymer Conjugates and their Characterization -- Biocompatibility of Polymers -- Sterilization techniques of biomaterials (implants and medical devices).
    Abstract: This book intends to serve as textbook for faculty and students and thus contains a broad introduction and basic terms of biomterials and biopolymers followed by major developments over the years with some emphasis on recent developments and future prospects. The book provides a comprehensive overview in biomaterials and biopolymers. All relevant aspects of modern biomaterials, including: synthesis and characterization, biocompatibility and host respond, the implementation of novel manufacturing processes, and advanced medical and biotechnological applications. Each chapter provides an overview of a specific field, its importance, the chemistry of biomaterials and the relations between chemical structure and the applications. Each chapter ends with a future prospective/concepts and a friendly quiz/multiple answer questions with answers that serves as a resource to provide guided additional practice.
    Type of Medium: Online Resource
    Pages: XII, 272 p. 76 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031361357
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 7
    URL: https://doi.org/10.1007/978-3-031-36135-7
    DOI: 10.1007/978-3-031-36135-7
    DDC: 615.19
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 6
    Online Resource
    Online Resource
    Metabolomics : Recent Advances and Future Applications (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Metabolism. ; Biochemical markers. ; Plant diseases. ; Cancer. ; Neurosciences. ; Drug delivery systems. ; Metabolism. ; Biomarkers. ; Plant Pathology. ; Cancer Metabolism. ; Neuroscience. ; Drug Delivery.
    Description / Table of Contents: Introduction of metabolomics -- Metabolomics Data Analysis and Tools -- Role of metabolomics in the development of new avenues in fundamental biology research -- Metabolomics in epidemiology -- Pharmacometabolomics: General use of metabolomics in pharmacy and drug development -- Metabolomics in microbiological research and applications -- Application and developments of metabolomics in physiological diseases -- Nutrimetabolomics: metabolomics in nutrition research -- Metabolomics in natural product discovery and their application -- Metabolomics approach in environmental studies -- Emerging metabolomics methodologies, and research in agriculture -- Metabolomics in fundamental plant research -- Integration of metabolomics with other omics: tools and general applications -- Future perspectives of metabolomics: gaps, recommendations, and planning.
    Abstract: This book Introduces the extensive applications of metabolomics from all possible areas of research and development so that not only an undergraduate can understand the advancement of metabolomics, but an entrepreneur can harness the knowledge to address possible problems to make a perfect tool to address their research question. Topics covered include the role of metabolomics in the development of agriculture, plant pathology, and their applications; the generalized application of the metabolomics and use of related technologies in various sectors of industries; and the future of metabolomics and upcoming related technologies that can fill the gap between different -omics and their applications for the betterment of humankind. This is an ideal book for university professors, researchers, and advanced-level scientists who are exploring different avenues in metabolomics. Availability of this concise information in one place will aid scientists by expanding their arsenal of techniques and can be helpful to bring more collaborations and to identify the expert at the global level.
    Type of Medium: Online Resource
    Pages: XIV, 517 p. 94 illus., 85 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031390944
    URL: https://doi.org/10.1007/978-3-031-39094-4
    DOI: 10.1007/978-3-031-39094-4
    DDC: 572.4
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 7
    Online Resource
    Online Resource
    Advanced Drug Delivery : Methods and Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Drug delivery systems. ; Biomedical engineering. ; Nanobiotechnology. ; Microfluidics. ; Cytology. ; Pharmaceutical chemistry. ; Drug Delivery. ; Biomedical Engineering and Bioengineering. ; Nanobiotechnology. ; Microfluidics. ; Cell Biology. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. Biological methods -- Chapter 2. Liposomal based drug delivery system -- Chapter 3. Hydrogel-based drug delivery strategies -- Chapter 4. Monoclonal antibodies -- Chapter 5. Electroporation -- Chapter 6. Photoporation -- Chapter 7. Mechanoporation -- Chapter 8. Magnetoporation -- Chapter 9. Microinjection -- Chapter 10. Jet injection -- Chapter 11. Sonoporation -- Chapter 12. Device based drug delivery techniques – microfluidics Chapter 13. Nanoparticles drug delivery systems -- Chapter 14. BioMaterials -- Chapter 15. Implanted drug delivery systems -- Chapter 16. Transdermal drug delivery systems -- Chapter 17. Subcutaneous drug delivery systems -- Chapter 18. Nasopulmonary drug delivery systems -- Chapter 19. Mucosal drug delivery systems -- Chapter 20. Intrauterine drug delivery systems -- Chapter 21. Gastro retentive drug delivery systems -- Chapter 22. Endoscopic assisted drug delivery -- Chapter 23. Theranostics.
    Abstract: This book provides an overview of various drug delivery systems at the cellular level including biological, chemical methods, and most importantly physical methods such as photoporation, electroporation, mechanoporation, and device-based techniques (e.g., microfluidics), as well as organism-level techniques including nanomaterials, biomaterials, and transdermal. Drug delivery (DD) can be defined as the method and route by which an active pharmaceutical ingredient (API) is administered to promote its desired pharmacological effect and/or convenience and/or to reduce adverse effects. Drug delivery systems are developed to maximize drug efficacy and minimize side effects. As drug delivery technologies improve, the drug becomes safer and more comfortable for patients to use. During the last seven decades, extraordinary progress has been made in drug delivery technologies, such as systems for long-term delivery for months and years, localized delivery, and targeted delivery. The advances, however, will face the next phase considering the future technologies that we need to overcome many physicochemical barriers for new formulation development and biological unknowns for treating various diseases. Thus, various technologies are built at a single-cell level as well as an organism level. This book is useful at the university level for graduate courses or research studies and biotechnology-based companies with research and development on cell-based analysis, diagnosis, or drug screening. This book is also very useful for researchers in drug delivery technologies, which came in frontier research for the past decade.
    Type of Medium: Online Resource
    Pages: X, 362 p. 92 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819965649
    Series Statement: Studies in Mechanobiology, Tissue Engineering and Biomaterials, 26
    URL: https://doi.org/10.1007/978-981-99-6564-9
    DOI: 10.1007/978-981-99-6564-9
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 8
    Online Resource
    Online Resource
    Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    URL: https://doi.org/10.1007/978-981-99-6917-3
    DOI: 10.1007/978-981-99-6917-3
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 9
    Online Resource
    Online Resource
    Nano- and Microfabrication Techniques in Drug Delivery : Recent Developments and Future Prospects (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacy. ; Drug Delivery. ; Pharmaceutics. ; Pharmacy.
    Description / Table of Contents: 1. Conducting polymers as drug release systems -- 2. Electrospinning for drug delivery applications -- 3. Melt-electrospinning and electrowriting for pharmaceutical and biomedical applications -- 4. Pharmaceutical Spray Drying -- 5. Vat photopolymerization 3D printing for drug delivery applications -- 6. Semi-solid extrusion 3D printing for the development of dosage forms for special patient groups -- 7. Binder-Jetting Powder bed 3D‐printing for the fabrication of drug delivery systems -- 8. 3D printing for localized cancer therapy -- 9. 4D Printing in Pharmaceutics & Biomedical Applications -- 10. Lithography in Drug-Delivery -- 11. Micro-moulding and its application to drug delivery -- 12. Supercritical Fluids: A Promising Technique in Pharmaceutics -- 13. Microfluidics as a tool for the synthesis of advanced drug delivery systems -- 14. Nanofluidic Technologies for Drug Screening and Drug Delivery -- 15. Nanoparticles at the stage of clinical trials -- 16. Nasal drug delivery systems for the treatment of diseases of the central nervous system and tuberculosis -- 17. Regulatory aspects and barriers in using ground-breaking technologies. .
    Abstract: New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs. Nano- and microfabrication techniques include manufacturing methods such as additive manufacturing, lithography, micro-moulding, spray drying, and supercritical fluids among many others. The increasing resolution of new techniques allow researchers to produce objects with micrometric resolutions. This book follows a consecutive order, beginning with a background in the current field and limitations in the manufacturing of different pharmaceutical products, moving on the classification of each method by providing recent examples, and future prospective on a variety of traditional and new Nano and microfabrication techniques. A focus on the materials used to prepare these systems and their biocompatibility, including applied topics such as clinical applications and regulatory aspects also covered, offering the reader a holistic view of this rapidly growing field.
    Type of Medium: Online Resource
    Pages: XIII, 491 p. 103 illus., 87 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031269080
    Series Statement: Advanced Clinical Pharmacy - Research, Development and Practical Applications, 2
    URL: https://doi.org/10.1007/978-3-031-26908-0
    DOI: 10.1007/978-3-031-26908-0
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 10
    Online Resource
    Online Resource
    Infectious Diseases Drug Delivery Systems (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Diseases. ; Pharmacology. ; Epidemiology. ; Pharmaceutical chemistry. ; Drug Delivery. ; Diseases. ; Pharmacology. ; Epidemiology. ; Pharmaceutics.
    Description / Table of Contents: New drugs in synthesis research for Malaria -- New drugs in synthesis research for TB -- New drugs in synthesis viral -- Nanotechnology in Malaria diagnosis -- Nanotechnology in TB diagnosis -- Nanotechnology based vaccination Malaria -- Nanotechnology based vaccination TB -- Disease models in Malaria research -- Disease models in TB research -- Disease models in Viral research -- Viral diseases- cellular understanding of disease : Vaccine development -- Pneumonia- infection -- bacterial pnuemonia -- Lipid based DDS in pneumonia -- hepatitis -- Recent Developments in the Treatment of Bacterial Meningitis -- Bacterial Urinary Tract Infections -- E.coli.
    Abstract: The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the micro-organisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, the infectious diseases will undoubtedly persist as permanent and main threats to humanity for now and in the future. A total of four books are covered under the series of Infectious drug diseases. - Malarial drug delivery systems - Tubercular drug delivery systems - Viral drug delivery systems - Infectious disease drug delivery systems Infectious diseases are the world’s greatest killers that present one of the most significant health and security challenges. Humans have lived with emerging and re-emerging pathogens since before the documented history of civilization. The only determining fact today is - If the situation is “worse” or “better” than in past. The answer is probably “worse”, may be due significant increase in human population, increased cross-continent mobility, imbalanced (stressed) life style, irregular food habits leading to compromised innate immunity and over or under practiced hygiene routine. When the incidence of such a disease in people increases over 20 years or threatens to increase, it is called an “emerging” disease, and a growing number have made watch lists and headlines in nearly every country -like highly pathogenic H5N1 avian influenza, severe acute respiratory syndrome (SARS), Ebola virus, food- and waterborne illnesses, and a range of antimicrobial-resistant bacterial diseases TB. This book addresses current and new therapy developments in treating such infectious diseases, updates on finding new drugs, identification of innovative diagnostic methods, understanding of disease research models and clinical trials performances of new treatment modalities. Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of infectious diseases and related research.
    Type of Medium: Online Resource
    Pages: X, 439 p. 41 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031205217
    URL: https://doi.org/10.1007/978-3-031-20521-7
    DOI: 10.1007/978-3-031-20521-7
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 11
    Online Resource
    Online Resource
    Biomaterials and Tissue Engineering (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Regenerative medicine. ; Stem cells. ; Biomaterials. ; Nanotechnology. ; Drug delivery systems. ; Biomedical engineering. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology. ; Biomaterials. ; Nanotechnology. ; Drug Delivery. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Introduction of Biomaterials and Tissue Engineering -- Chapter 2. Tissue regeneration processing and mimicking -- Chapter 3. Cell sources for Tissue Engineering -- Chapter 4. Biomaterials -- Chapter 5. Micro and nanotechnology -- Chapter 6. Bioceramics -- Chapter 7. Drug delivery for Tissue Engineering -- Chapter 8. Cell-material interaction -- Chapter 9. Bioreactors -- Chapter 10. Scaffolds fabrication processes -- Chapter 11. Characterization of the biological response to scaffolds -- Chapter 12. Additive Manufacturing -- Chapter 13. Bioprinting -- Chapter 14. Outlook and future perspectives.
    Abstract: This contributed volume covers all fundamental principles for researchers and professionals interested in the field of Biomaterials and Tissue Engineering, an interdisciplinary field of research with contributions from biomedical scientists, engineers, and physicians. With a strong focus on biomaterials and scaffolds, the book also covers testing and evaluation pathways for in vitro and in vivo studies. This book also presents a broad range of topics including fundamentals of 3D printing and bioprinting, followed by contemporary technology used in tissue engineering applications as well as currently available biomaterials suitable for tissue repair and regeneration. This volume provides information on: (i) why humans need biomaterials, especially in medical applications, (ii) different types of tissue engineering strategies, and (iii) modeling, characterization, and evaluation of outputs of those strategies. This book is a reference material in the field of tissue engineering, and it is very useful for bachelor, M.Sc., and Ph.D. students, researchers, academics, medical, industry, and healthcare professionals from diverse backgrounds.
    Type of Medium: Online Resource
    Pages: XII, 387 p. 118 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031358326
    Series Statement: Stem Cell Biology and Regenerative Medicine, 74
    URL: https://doi.org/10.1007/978-3-031-35832-6
    DOI: 10.1007/978-3-031-35832-6
    DDC: 612.028
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 12
    Online Resource
    Online Resource
    Novel Technologies in Biosystems, Biomedical & Drug Delivery (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Drug delivery systems. ; Genetics Research. ; Imaging systems in biology. ; Biology Technique. ; Biomedical Research. ; Drug Delivery. ; Genetics Research. ; Biological Imaging. ; Biological Techniques.
    Description / Table of Contents: Chapter 1. Editorial: Biosystems -- 2. Potential of Biotechnology in cancer management -- 3. Biosimilars: Promising and Rapidly Emerging Biotherapeutics -- 4. Applications of Nanomaterials in Medicine: Current status and future scope -- 5. Biomedical Applications of Nanofluids in Drug Delivery.
    Abstract: The book gives an insight into the theoretical background, conceptual understanding, latest developments, and applications in the field of pharmaceuticals in general and drug design, discovery, biosystems, and biomedical and drug delivery technologies in particular . Knowledge is drawn from various disciplines such as Chemistry, Biology, Material Science and Engineering, Statistics, Biomedicine, and Genetics . A host of applications like bio-imaging, novel biological agents, testing, characterization and validation of drugs, computer-based models in drug design, and application of statistical tools in data analysis, design, and development of drug delivery systems, and ecosystems are dealt with in detail. The said book undoubtedly confirms the requirements of the postgraduate students, research scholars, academicians, scientists, and researchers from the academia, pharmaceutical, biotechnology, and chemical engineering domain. The book covers a conceptual understanding of the exploration of drugs in tandem with intended uses, sound ecosystem development, and carriers for drug and supplement delivery.
    Type of Medium: Online Resource
    Pages: XX, 289 p. 58 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819952816
    URL: https://doi.org/10.1007/978-981-99-5281-6
    DOI: 10.1007/978-981-99-5281-6
    DDC: 610.72
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 13
    Online Resource
    Online Resource
    CPP, Cell-Penetrating Peptides (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Proteins. ; Pharmacology. ; Proteins . ; Medicinal chemistry. ; Biomaterials. ; Drug Delivery. ; Proteins. ; Pharmacology. ; Protein Biochemistry. ; Medicinal Chemistry. ; Biomaterials-Proteins.
    Description / Table of Contents: 1. Introduction -- 2. Classes and applications of CPP -- 3. CPP selection, prediction and in silico analysis -- 4. Labeling of CPPs -- 5. Methods for CPP functionalization with oligonucleotides -- 6. Additional (gene therapeutic) platforms -- 7. Protein delivery and mimicry -- 8. General targeting strategies -- 9. Targeting specific barriers -- 10. Methods for molecular imaging, detection and visualization of CPPs -- 11. Methods for structural studies of CPPs -- 12. Kinetics -- 13. Toxicity and immune response -- 14. Cell-translocation mechanisms of CPPs -- 15. Clinical trials and commercialization using CPPs -- 16. Therapeutic potential of CPPs -- 17. CPP functionalized nanoparticles -- 18. Concluding remarks.
    Abstract: In this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising relevant questions for further development. The CPP sequences are presented and discussed throughout the book. The methods for testing CPP mechanisms are discussed in detail. Various approaches for the testing of endocytotic pathways of CPP uptake are also described. Different CPP uptake experiments are compared since it is becoming clear that it is often best to apply several methods in a complementary manner in order to most comprehensively evaluate CPP uptake mechanisms due to the complexity of these processes. A brief summary of functionality issues of CPPs, both in vitro and in vivo, is discussed. Therapeutic potential of CPPs and commercial developments are discussed. The present, second edition of this book is the updated and expanded version of the first edition, published in 2019. The development of the field of cell-penetrating peptides in these five years has been obvious and exciting. This second edition of the book has been partly reorganized and comprehensively expanded with the exciting research in 2019-2023. Around 2500 novel scientific articles have become available, most of them are reviewed in the second edition. Additional rapidly growing areas of high impact presented in this second edition are therapeutic developments (Chapter 16) and delivery of oligonucleotides and proteins/peptides (Chapters 5 and 6) including novel reports on genome editing with CPP assistance. Also, several additional examples are available now on clinical trials using CPPs (Chapter 15). The book is written for researchers and students in the field.
    Type of Medium: Online Resource
    Pages: XXI, 556 p. 26 illus., 19 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031387319
    URL: https://doi.org/10.1007/978-3-031-38731-9
    DOI: 10.1007/978-3-031-38731-9
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 14
    Online Resource
    Online Resource
    The Quintessence of Basic and Clinical Research and Scientific Publishing (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Drug delivery systems. ; Medical Ethics. ; Clinical Research. ; Biomedical Research. ; Drug Delivery. ; Medical Ethics.
    Description / Table of Contents: Chapter 1. The Roadmap to Research: Fundamentals of a Multifaceted Research Process -- Chapter 2. Processes involved in the generation of novel ideas -- Chapter 3. Creativity and critical thinking contribute to scholarly achievement -- Chapter 4. Writing protocols in Pharmacological studies -- Chapter 5. Basics of Designing General Toxicology Studies -- Chapter 6. General design considerations in Reproductive and developmental toxicity studies -- Chapter 7. Genetic toxicology studies -- Chapter 8. Rodent Carcinogenicity Studies.-Chapter 9. Designing studies in pharmaceutical and medicinal chemistry -- Chapter 10. Experimental protocols in phytochemistry and natural products: an ever-evolving challenge -- Chapter 11. Drug substance/ product quality analysis (Quality assessment) -- Chapter 12. Drug Delivery Systems: Lipid Nanoparticles Technology in Clinic -- Chapter 13. Pharmacokinetic studies for drug development -- Chapter 14. New Alternative Methods in drug safety assessment -- Chapter 15. Animal models for the study of human disease -- Chapter 16. Physiologically based Pharmacokinetic Modelling in Drug Discovery and Clinical Development: A Treatise on Concepts, Model Workflow, Credibility, Application and Regulatory Landscape -- Chapter 17. Design and conduct of pharmacokinetics studies influenced by extrinsic factors -- Chapter 18. Specific Populations: Clinical Pharmacology Considerations -- Chapter 19. Impact of genetic variation on drug response.-Chapter 20. Phases of clinical trials -- Chapter 21. Common clinical trial designs -- Chapter 22. Elements of clinical trial protocol design -- Chapter 23. Good clinical practice in clinical trials, substantial evidence of efficacy, and interpretation of the evidence -- chapter 24. Grandfathered Drugs of 1938 in the United States -- Chapter 25. General overview of the statistical issues in clinical study designs -- Chapter 26. Introduction to pharmacoepidemiology and its application in clinical research -- Chapter 27. Pharmacovigilance through phased clinical trials, post-marketing surveillance and ongoing life cycle safety -- Chapter 28. The design and statistical analysis of randomized pre-clinical experiments -- Chapter 29. Descriptive and Inferential Statistics in Biomedical Sciences: an overview -- Chapter 30. Principles and applications of statistics in biomedical research: parametric and non-parametric tests including tests employed for Post-hoc analysis -- Chapter 31. Artificial intelligence generative chemistry design of target-specific scaffold-focused small molecule drug libraries -- Chapter 32. Artificial intelligence technologies for clinical data pharmacoanalytics. Case studies on Alzheimer’s disease -- Chapter 33. Bioinformatics: Theory and Application -- Chapter 34. Drug targets and drug discovery research -- Chapter 35. Role of Nonclinical Programs in Drug Development -- Chapter 36. Drug repurposing: strategies and study design in bringing back old drugs to the mainline -- Chapter 37. Empowering knowledge on efficient literature search: an overview of biomedical search engines and databases -- Chapter 38. Literature Reviews: An Overview of Systematic, Integrated, and Scoping Review -- Chapter 39. How To Create A Bibliography -- Chapter 40. Publication metrics /Bibliometrics -- Chapter 41. How to write a scientific paper -- Chapter 42. Preparing and structuring a manuscript for publication -- Chapter 43. Writing a scientific article -- Chapter 44. How to Present Results in a Research Paper -- Chapter 45. Communicating results of quantitative research -- Chapter 46. How to Efficiently Write a Persuasive Discussion Section -- Chapter 47. Submitting a manuscript for publication, the peer review process, and getting past the gatekeepers -- Chapter 48. Writing a Postgraduate or Doctoral Thesis: A Step-by-Step Approach -- Chapter 49. Poster presentation at scientific meetings -- Chapter 50. Strategies for the preparation and delivery of oral presentation -- Chapter.-51. Grant Process and Peer Review ─ US National Institutes of Health System -- Chapter 52. Rigor and specifics in writing research proposal -- Chapter 53. Writing research grant proposals ─ from an Indian Perspective -- Chapter 54. Funding opportunities (resources) in biomedical sciences: Indian perspective -- Chapter 55. Mentorship in biomedical sciences -- chapter 56. Commercializing the technology – transitioning from the academic lab to the market -- Chapter 57. Patent law fundamentals for biomedical scientists -- Chapter 58. Research integrity: responsible conduct of research -- Chapter 59. Publication integrity, authorship, and misconduct.
    Abstract: The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated into the text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.
    Type of Medium: Online Resource
    Pages: XXII, 941 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819912841
    URL: https://doi.org/10.1007/978-981-99-1284-1
    DOI: 10.1007/978-981-99-1284-1
    DDC: 615.50724
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 15
    Online Resource
    Online Resource
    Spray Drying of Vaccines : From Laboratory Research to Industrial Applications (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Drug delivery systems. ; Vaccines Biotechnology. ; Biomaterials. ; Immunotherapy. ; Biomedical Research. ; Drug Delivery. ; Biomaterials-Vaccines. ; Immunotherapy.
    Description / Table of Contents: Chapter 1 A short introduction to vaccines -- Chapter 2 Thermostability of vaccines -- Chapter 3 Drying technologies for vaccines -- Chapter 4 Aseptic spray drying technology -- Chapter 5 Design of experiment studies and scale-up -- Chapter 6 Applications of spray dried vaccines.-Chapter 7 Conclusions and future perspectives of spray-dried vaccines.
    Abstract: This book addresses the stabilization of vaccine powders by spray drying and provides an overview of the current state of the art on a laboratory and industrial scale. The book aims to familiarize readers with the advances in vaccine spray drying technology to understand its application potential better. In particular, the book addresses the design of aseptic spray dryers, parameters affecting the spray drying process, sterile powder processing, cleaning procedures, and powder filling. In addition, different drying technologies for the production of dry powder vaccines are compared to discuss the unique capabilities of spray drying as a particle technology for vaccines. Special attention is given to research studies on spray-dried vaccines published over the past 30 years, with key findings from laboratory research to clinical trials. Potential applications of spray-dried vaccines and routes of administration are presented in detail. Finally, an outlook is given on how close the aseptic spray-drying of vaccines is to the market and the challenges that need to be overcome to be commercially successful. The book's target audience is academics, researchers, vaccine developers, industry experts, students, and possibly funders, including government agencies, who are active in the field. In addition, the book is a reference source for those involved in the vaccine formulation and biopharmaceutical processing industry.
    Type of Medium: Online Resource
    Pages: XXIX, 589 p. 243 illus., 176 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031243233
    URL: https://doi.org/10.1007/978-3-031-24323-3
    DOI: 10.1007/978-3-031-24323-3
    DDC: 610.72
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 16
    Online Resource
    Online Resource
    Viral Drug Delivery Systems : Advances in Treatment of Infectious Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Pharmaceutical chemistry. ; Diseases. ; Pharmacology. ; Epidemiology. ; Pharmacy. ; Drug Delivery. ; Pharmaceutics. ; Diseases. ; Pharmacology. ; Epidemiology. ; Pharmacy.
    Description / Table of Contents: Global health and Viral diseases past, present and Future -- Drug resistance and statistics and patent status -- cellular understanding viral diseases -- Viral: current treatment options -- Mucosal drug delivery strategies for antiviral intervention -- Micro, nano emulsions in viral -- Novel formulation approaches to treat Ebola- virus -- Ebola- drug delivery -- Polymers for Bio sensing Applications in antiviral therapy and diagnosis -- Nanotechnology: A Stepping Stone towards Viral Hepatitis Treatment and Prevention in Children -- Recent Developments in the Treatment of Influenza -- Covid 19: from molecular pathogenesis to potential repurposed treatments -- Nano drug delivery systems for Covid-19-drug delivery -- Exploring the link between malaria and Covid 19 -- Characterization of biofunctionalized nanoparticles in ID -- Covid- azithromycin-ritonavir -- Strategies to combat Covid-19 drug delivery -- Phytomolecules and NDDS Covid-19.
    Abstract: The disability-adjusted life year (DALY) is a generic measure of health effect that can be used in cost-effectiveness analysis as an alternative to the quality-adjusted life year (QALY). Infectious diseases are one of the major to cause significant losses of DALY and QALY. Human infectious diseases are disorders that are triggered by the micro-organisms such as bacteria, fungi, viruses, or parasites. The majority of such diseases are contagious and create a public health menace. There are several reasons why infectious diseases are deadly diseases, and one of the primary reasons is the drug resistance developed over time. Drug resistance-associated mutations are linked to increasing drug efflux, modifications of the drugs, or their targets. Every year, new drugs are being approved by FDA to treat infectious diseases. Nonetheless, the infectious diseases will undoubtedly persist as permanent and main threats to humanity for now and in the future, primarily due to increased longevity that almost always comes at a cost of impaired immunity. A total of four books are covered under the series of Infectious drug diseases. - Malarial drug delivery systems - Tubercular drug delivery systems - Viral drug delivery systems - Infectious disease drug delivery systems The third volume of series is focused on viral drug delivery systems. Typically, virus attaches to the cells (referred as host cell) and releases its DNA or RNA inside the cell. In second stage, virus’s genetic material takes control of the cell and forces it to replicate the virus leading to onset of disease symptoms. DNA class of viruses include Herpes, Papilloma and Adeno viruses. RNA class of viruses include retroviruses, such as HIV immunodeficiency virus and SARS COV – 2 / Corona virus. This book addresses recent developments in viral drug delivery systems. It covers many different aspects of viral infections, ways to treat them using modern drug delivery systems like nano particulate carriers. The choice of viral delivery systems mainly depends upon the type of virus, duration of life cycle, presence of drug resistance, cellular and mucosal interaction of virus, accordingly gene or non-gene drug delivery systems are selected. Besides that, this book also reports global dynamics of viral diseases, future predictions of infection rate, current treatment options, details of drug carriers like nanoemulsions, polymeric nanoparticles, role of biofunctionalization, and phyto-molecules in treatment of viral infections particularly herpes, Covid-19, Ebola, HIV/AIDS, influenza and viral hepatitis. Audiences from a broad range of groups, from researchers, academicians, and public health bodies to regulatory experts, can benefit from the compiled information to learn more about patient needs and current research advances in the field of viral drug delivery research.
    Type of Medium: Online Resource
    Pages: X, 409 p. 53 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031205378
    URL: https://doi.org/10.1007/978-3-031-20537-8
    DOI: 10.1007/978-3-031-20537-8
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 17
    Online Resource
    Online Resource
    Advances in Pharmacokinetics and Pharmacodynamics (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Drugs Design. ; Pharmaceutical chemistry. ; Metabolism. ; Pharmacology. ; Clinical biochemistry. ; Drug Delivery. ; Structure-Based Drug Design. ; Pharmaceutics. ; Metabolism. ; Pharmacology. ; Medical Biochemistry.
    Description / Table of Contents: Pharmacokinetics -- Chapter 1: Current status in PBPK modeling -- Chapter 2: Physiologically based biopharmaceutics modeling (PBBM) Application on Food Effect Assessment -- Chapter 3: Physiologically based finite time pharmacokinetic (PBFTPK) models: Inception and development -- Chapter 4: Physiologically based finite time pharmacokinetic (PBFTPK) models: Applications -- Pharmacodynamics -- Chapter 5: Pharmacokinetic – Pharmacodynamic Modelling and Simulation in Clinical Practice and Studies -- Chapter 6: On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body -- Chapter 7: Impact of Clinical Pharmacology on the Modernization of Drug Development and Regulation.
    Abstract: This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
    Type of Medium: Online Resource
    Pages: XI, 204 p. 37 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031295416
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 9
    URL: https://doi.org/10.1007/978-3-031-29541-6
    DOI: 10.1007/978-3-031-29541-6
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 18
    Online Resource
    Online Resource
    Polymeric Micelles: Principles, Perspectives and Practices (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery.
    Description / Table of Contents: 1. Synthesis, self-assembly and functional chemistry of Amphiphilic block copolymers -- 2. Advances in polymer optimisation for enhanced drug delivery -- 3. Dynamics of Micelle Formation -- 4. Types of Polymeric Micelles for Controlled Drug Release -- 5. Drug Solubilization and Drug Release from Polymeric Micelles -- 6. Physical and Analytical Techniques used for the Characterization of Polymeric Micelles -- 7.Stimuli-sensitive polymeric micelles for biomedical applications -- 8.Nucleic acid-based micellar therapy for the treatment of different diseases -- 9. Polymeric micelles in the delivery of therapeutic phytoconstituents -- 10. Diagnostic applications of surface-engineered polymeric micelles -- 11. Ligand conjugated polymeric micelles for targeted delivery of drug payloads in cancer therapy -- 12. Polymeric Micelles in the Delivery of Proteins -- 13. Regulatory aspects for polymeric micelles -- 14. Toxicological and regulatory challenges in design and development of polymeric micelles -- 15. Stability of polymeric micelles and their regulatory status.
    Abstract: This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.
    Type of Medium: Online Resource
    Pages: XV, 294 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903610
    URL: https://doi.org/10.1007/978-981-99-0361-0
    DOI: 10.1007/978-981-99-0361-0
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 19
    Online Resource
    Online Resource
    Technology Transfer : Drug Product Manufacturing Process (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacy. ; Pharmaceutical chemistry. ; Pharmacology. ; Drug delivery systems. ; Pharmacovigilance. ; Pharmacy. ; Pharmaceutics. ; Pharmacology. ; Drug Delivery. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1: Current Status of Technology Transfer -- Chapter 2: Quality by Design (QbD) Process Design -- Chapter 3: Quality Risk Management (QRM) -- Chapter 4: Technology Transfer Process -- Chapter 5: Scaling-Up of Solid Orals: Granulation, Drying, Size Reduction, Blending, Compression, and Coating Technologies -- Chapter 6: Qualification, Continued Process Verification, and Lifecycle Management -- Chapter 7: Continuous Improvement Case Study: Transforming Legacy Products.
    Abstract: Currently, there are no textbooks on drug product manufacturing technology transfer that incorporate the latest regulatory expectations. Recent guidance from regulatory bodies such as the US FDA, EMEA, WHO, and PIC/S has adopted the ICH Lifecycle approach harmonizing concepts across regulatory guidance. This allows organizations to align their technology transfer activities for all regulated markets. However, there is a need for consensus and direction in approaching technology transfer, particularly in understanding how to manage the scale-up effects to ensure regulatory compliance. This textbook offers technology transfer solutions and guidance to the pharmaceutical industry. The chapters provide a systematic understanding of applying the technology transfer concepts in pharmaceutical manufacturing, promoting standardization within the industry. Since Stage 1b is not specified in detail within the regulations, pharmaceutical organizations are left to determine the requirements of the stage. The need to justify the methodologies and utilization of sound science makes it more demanding. The textbook’s authors provide innovative solutions for technology transfer challenges, making it a comprehensive reference document. The approaches can be applied to both small-molecule and large-molecule drug product manufacturing segments, addressing the unmet needs of the industry.
    Type of Medium: Online Resource
    Pages: XIV, 148 p. 78 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031321924
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 10
    URL: https://doi.org/10.1007/978-3-031-32192-4
    DOI: 10.1007/978-3-031-32192-4
    DDC: 615.1
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 20
    Online Resource
    Online Resource
    Drugs and a Methodological Compendium : From bench to bedside (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Drug delivery systems. ; Biology. ; Pharmaceutical chemistry. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Drug Delivery. ; Biological Sciences. ; Pharmaceutics. ; Biomedical Research.
    Description / Table of Contents: Chapter 1.Computational and informatics methodologies in Drug Discovery, with focus on Natural Products -- Chapter 2.Structural biology an essential tool for Drug discovery and Development -- Chapter 3.Bioactivity guided fractionation and identification of bioactive molecules: A basic method in drug discovery -- Chapter 4.In–vitro methodologies for the safety assessment of drugs -- Chapter 5.In-vivo models for evaluation of Drug efficacy: Demand and Challenges -- Chapter 6.Preclinical In vivo Drug Development Studies: Limitations, Model Organisms and Techniques -- Chapter 7.Peptide Based Therapeutics and Drug Delivery Systems -- Chapter 8.Basics of Clinical Drug Development: Clinical Trial and Drug Development -- Chapter 9.Trailblazing contemporary frameworks for drug repurposing: A saga on drugs’ expedition to disinter the veiled destiny -- Chapter 10.Small molecules as promising tool for targeted cancer therapies: an overview of 21st century -- Chapter 11.Nanoparticles for Targeted Drug Delivery Systems with Cancer Therapy in Perspective -- Chapter 12.Biomimetic approach for the controlled drug delivery through 3D bioactive scaffolds: A novel strategy for tissue engineering applications -- Chapter 13.Perspectives on anti-tuberculosis drug discovery -- Chapter 14.Cofactor-Receptor interactions based pharmacophore design for development of novel inhibitors: A case study against Tuberculosis -- Chapter 15.Insilico identification of potential antivirals against SARS-CoV2 main protease and RBD of spike protein – A Drug Repurposing Approach -- Chapter16.Anti-malarial drug discovery and development: from bench to bedside.
    Abstract: This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside. The current book threads almost each step encompassing drug the discovery and development of a molecule. The chapters focus on computational modus operandi, pharmacological optimization approaches, modern high-throughput screening methods and in-vitro procedures, role of structural biologists in drug discovery and development, medicinal chemistry approaches for drug design, formulation and drug delivery, in-vivo evaluations of candidate molecules, clinical trial procedures and others. The book also covers specific case studies, regulatory approval proceedings, and industrial view point alongside the aforementioned conceptual layout. And at the same time, the volume integrates medical, biological, medicinal, pharmacological and computational streams, and it is suggested as an ideal guideline to a wide audience including molecular biologists, biochemist, pharmacologists, medicinal chemist, toxicologists, drug discovery and development researchers, and all other students interested in these disciplines. .
    Type of Medium: Online Resource
    Pages: XV, 425 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811979521
    URL: https://doi.org/10.1007/978-981-19-7952-1
    DOI: 10.1007/978-981-19-7952-1
    DDC: 660.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 21
    Online Resource
    Online Resource
    Pharmaceutical Formulations for Older Patients (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Medicine Research. ; Biology Research. ; Drug Delivery. ; Pharmaceutics. ; Pharmacology. ; Biomedical Research.
    Description / Table of Contents: Part 1: Patient-Centric Considerations.-Medicine Optimisation in Older -- Acceptability of drug formulations in older patients and effect on patient adherence -- Geriatric biopharmaceutics -- Excipient safety in older adults -- Part 2: Pharmaceutical Formulations Development for older Patients -- Oral and oromucosal formulation development and in vitro characterisation – patient-centric approaches for older adults -- Pulmonary drug delivery systems for older people -- Transdermal drug delivery systems for older patients -- Part 3 :Advanced Drug Delivery Systems for Older Patients -- Advanced oral drug delivery systems for older patients -- The ageing microbiome, pharmaceutical considerations and therapeutic opportunities -- Application of 3D printing in geriatric medicines, -- Application of electrospraying and advanced fabrication methods in geriatric medicines -- Vaccine development for older patients.
    Abstract: Pharmaceutical formulation design affects patient acceptability/adherence and pharmacokinetics of the drug. This is particularly important for older patients because of the physiological changes due to ageing and clinical/social circumstances related to medicine taking. This book provides a comprehensive review in the design of formulations to meet the needs of older patients. An overview of the key clinical, social and pharmaceutical factors affecting medication optimization, safety and acceptability in older adults is included, followed by patient-centric considerations including regulatory requirements, dosage form design and human factor studies. Advanced pharmaceutical technologies are discussed for their potential use in older adults such as 3D printing, long-acting oral formulations and novel vaccine technologies. The unique focus of the book will be of interest to pharmaceutical scientists in both industry and academia in searching for better formulations for older patients.
    Type of Medium: Online Resource
    Pages: XIII, 288 p. 63 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031358111
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 51
    URL: https://doi.org/10.1007/978-3-031-35811-1
    DOI: 10.1007/978-3-031-35811-1
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 22
    Online Resource
    Online Resource
    Interaction of Nanomaterials With Living Cells (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Nanobiotechnology. ; Nanotechnology. ; Drug delivery systems. ; Regenerative medicine. ; Biomaterials. ; Cells. ; Nanobiotechnology. ; Nanotechnology. ; Drug Delivery. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials-Cells.
    Description / Table of Contents: Chapter 1. Role of synthetic and natural biomaterials in modulating the autoimmune response -- Chapter 2. Nanotechnology-based biosensors in medicine -- Chapter 3. Materials from natural resources for the application of bone tissue engineering -- Chapter 4. Hydroxyapatite is a next-generation theranostic probe for tissue engineering and biomedical application -- Chapter 5. Green synthesis of metallic nanoparticles and various biomedical applications -- Chapter 6. Functionalized carbon nanotube for various disease treatment -- Chapter 7. Nanotechnology: Changing the world of animal health and veterinary medicine -- Chapter 8. Bioinspired materials inherited with antimicrobial properties for tissue engineering -- Chapter 9. 3D and 4D bioprinting technology for tissue engineering applications -- Chapter 10. Hemocompatibility of differently modified polymeric nanofibers: Current progress in the biomedical industry -- Chapter 11. Polyurethane nanofibers fabricated by electrospinning as drug carriers systems for the treatment of cancer -- Chapter 12. Recent trends in the application of materials for cancer therapy and diagnosis -- Chapter 13. Application of bioactive compounds and biomaterials in promoting cell differentiation, proliferation, and regenerating tissue -- Chapter 14. Materials for gene delivery systems -- Chapter 15. Natural hydrogels as wound dressing for skin wound healing applications -- Chapter 16. Nanomaterial applications in cancer therapy and diagnosis -- Chapter 17. Nanocellulose as a sustainable nanomaterial for films and coating layers via spray-coating and applications -- Chapter 18. Nanoparticles-based drug delivery system for beginners -- Chapter 19. Osteoarthritis: Novel insights in treatment -- Chapter 20. Promoting the Bio-potency of Bioactive Compounds through Nanoencapsulation -- Chapter 21. Review on green synthesis, modification, characterization, properties, and applications of palladium nanoparticles in biomedical applications -- Chapter 22. Innovative nanomaterials with profound antibacterial action applied in biomedical sciences -- Chapter 23. Musculoskeletal pains and its common diseases: Novel insights in treatments using biomaterials -- Chapter 24. Electrospun Cellulose and Derivatives-Based Nanofibers Loaded with Bioactive Agents for Wound Dressing Applications -- Chapter 25. Co-Delivery of Anticancer Drugs Using Polymer-Based Nanomedicines for Lung and Prostate Cancer Therapy -- Chapter 26. Silver nanoparticles incorporated textile substrate for antimicrobial applications -- Chapter 27. Recent advancement of gelatin for tissue engineering applications -- Chapter 28. Biomedical applications of the fused filament fabrication (FFF) technology -- Chapter 29. Role of Stem cells in the Delivery of Essential Pharmaceuticals -- Chapter 30. Biomaterials in autoimmune diseases -- Chapter 31. Regulatory and ethical issues raised by the utilization of nanomaterials.
    Abstract: This book examines the interactions of nanomaterials with the biological system. The chapters of the book explore the natural and synthetic biomaterials that modulate immune responses for their applications in drug delivery and tissue engineering. Further, the book discusses the implications of the physiochemical properties of nanoparticles and their microenvironment on their interactions with biological systems. The chapters also present the recognitive capabilities of biomaterials for the development of novel strategies for the detection and treatment of autoimmune disorders. The book also introduces nanotechnology platforms for drug delivery and highlights current and emerging nanotechnologies that could enable novel classes of therapeutics. Towards the end, the book reviews the efficiency of drug-loaded nanoparticles in modulating the functioning of the biological milieu for improved disease treatment. Lastly, the book outlines the ethical issues regarding the use of nanoparticles for in vitro and in vivo applications. Given its scope, it is a valuable resource for graduate students and researchers interested in understanding the biomedical applications of nanoparticles and their interactions with the biological milieu.
    Type of Medium: Online Resource
    Pages: XXIII, 924 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819921195
    URL: https://doi.org/10.1007/978-981-99-2119-5
    DOI: 10.1007/978-981-99-2119-5
    DDC: 620.5
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 23
    Online Resource
    Online Resource
    Alginate Biomaterial : Drug Delivery Strategies and Biomedical Engineering (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Drug delivery systems. ; Biomaterials. ; Therapeutics. ; Biology Technique. ; Genetic engineering. ; Cancer Treatment. ; Biomedical engineering. ; Drug Delivery. ; Biomaterials. ; Therapeutics. ; Gene Delivery. ; Cancer Therapy. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. ALGINATE BASED MATRIX TABLET FOR DRUG DELIVERY -- Chapter 2. Alginate based micro particulate systems for drug delivery -- Chapter 3. Alginate based nanocarriers for controlled drug delivery applications -- Chapter 4. Alginate based carriers for topical drug delivery -- Chapter 5. Alginate based Hydrogel in drug delivery and biomedical applications -- Chapter 6. Alginate based interpenetrating polymer network (IPN) in drug delivery and biomedical applications -- Chapter 7. Alginate based micelle in biomedical applications -- Chapter 8. Alginate based polyelectrolyte complexes for drug delivery and biomedical applications -- Chapter 9. Alginate-Based Inhalable Particles for Controlled Pulmonary Drug Delivery -- Chapter 10. Biomedical Applications of Alginate in the Delivery System for Natural Products -- Chapter 11. Alginate in cancer therapy -- Chapter 12. Alginate carriers in wound healing applications -- Chapter 13. Alginate as support material in enzyme Immobilization -- Chapter 14. Alginate in Gene and Vaccine Delivery -- Chapter 15. Alginate based scaffolds in Tissue engineering and Regenerative Medicine.
    Abstract: This book focuses on recent trends of research on alginate-based biomaterials in Drug Delivery strategies and biomedical engineering. It contains the widely used alginate-based biomaterials as micro to nano-controlled drug delivery (oral, ocular delivery, topical delivery, etc.) and its fabrication technology, characterization, and biomedical aspects (such as cancer therapy, tissue engineering, gene delivery, vaccine delivery, enzyme immobilization, wound healing, dental applications, etc.) in a single book. The chapters cover updated information, current research trends, informatics, and all aspects of applications. Alginate is a U.S. Food and Drug Administration (FDA)-approved natural biomaterial and has diverse biomedical applications. In recent years, researchers and scientists are working on the alginate-based drug delivery systems that have been designed and characterized as a matrix, micro to nanocarriers, fibers, composite/scaffolds, etc. Alginate has versatile properties such as biodegradable, biocompatible, nontoxic, and easily available. This book especially highlights both the drug delivery strategies and biomedical engineering aspects such as controlled drug delivery, drug targeting to the site of action, cancer therapy, gene and vaccine delivery, enzyme immobilization, tissue engineering, and regenerative medicine. .
    Type of Medium: Online Resource
    Pages: VII, 423 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811969379
    URL: https://doi.org/10.1007/978-981-19-6937-9
    DOI: 10.1007/978-981-19-6937-9
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 24
    Online Resource
    Online Resource
    Nasal Drug Delivery : Formulations, Developments, Challenges, and Solutions (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Drug Delivery. ; Pharmaceutics. ; Pharmacology.
    Description / Table of Contents: An Overview of the Anatomy and Physiology of the Nasal Passage from a Drug Delivery Point of View -- Pharmacological and Clinical Problems with a Special Focus on Nasal Drug Delivery -- Nasal as an Absorption Site: Opportunities and Challenges -- Factors Affecting the Design of Nasal Drug Delivery Systems -- Challenges in Targeting to the Nasal Passage -- Potential Targeting Sites to Brain Through the Nasal Passage -- Drug Absorption to Systemic Circulation after Nasal Drug Delivery -- Delivery of Vaccine through Nasal Drug Delivery System -- An Overview on Nano Carriers for Nasal Delivery -- Biomedical Applications of Nano Carriers in Nasal delivery -- Novel muco-adhesive polymers for nasal drug delivery -- Novel approaches in Nasal in situ gel drug delivery -- Nasal delivery of high molecular weight drugs recent trends and clinical evidence -- Nisosomes based drug delivery in targeting the brain tumors via nasal delivery -- Nano suspension- A Novel Drug Delivery System via Nose to Brain drug delivery -- Different Strategies for nose-to-brain delivery of protein and peptide molecules -- Regulatory requirements related to Nasal drug delivery -- Is there a global market and opportunities for nasal drug delivery. .
    Abstract: This book addresses the recent trends and clinical research being reported in last 5 to 10 years in the field of nasal drug delivery systems. In recent years, interest in using nasal passage as drug absorption site has received increased attention from formulation scientists. Nasal passages, even though a small surface area of the body as compared to other absorption passage such as Gastrointestinal tract or skin, show significant possibility for drug absorption at a quicker rate. There is also a possibility of delivering drugs to the brain using this passage and targeting drugs through the nasal passage. The book has 19 chapters addressing various aspects of nasal drug delivery systems such as an overview of anatomy and physiology of the nasal passage from a drug delivery point of view to global market opportunities for nasal drug delivery. In between, it addresses various aspects of nasal drug delivery. There are very few titles exclusively dedicated to nasal drug delivery, covering the formulation and developmental aspects, and addressing the challenges and solutions. The primary audiences for the book are graduate students in field of medicine, pharmacy and also various researchers who are working in the area of nasal drug delivery in addition to students who are specializing in field of medicine in ENT. This book provides comprehensive information on all the aspects related to the nasal drug delivery of various drug molecules.
    Type of Medium: Online Resource
    Pages: XIV, 420 p. 39 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031231124
    URL: https://doi.org/10.1007/978-3-031-23112-4
    DOI: 10.1007/978-3-031-23112-4
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 25
    Online Resource
    Online Resource
    Additive Manufacturing in Pharmaceuticals (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmaceutical chemistry. ; Drug delivery systems. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Pharmacology.
    Description / Table of Contents: 1. History and Present Scenario of Additive Manufacturing in Pharmaceuticals -- 2. Fused deposition modeling (FDM) of Pharmaceuticals -- 3. Stereolithography (SLA) in Pharmaceuticals -- 4. Selective Laser Sintering (SLS) In Pharmaceuticals -- 5. Semi-solid Extrusion (SSE) in Pharmaceuticals -- 6. Inkjet and Binder Jet Printing in Pharmaceuticals -- 7. 4D printing: The next dimension of healthcare in cancer research -- 8. 4D Printing in Pharmaceuticals -- 9. Bioprinting in Pharmaceuticals -- 10. Regulatory Perspective of Additive Manufacturing in the Field of Pharmaceuticals -- 11. Machine Learning in Additive Manufacturing of Pharmaceuticals. .
    Abstract: This book presents the different 3D/4D printing technological applications of Additive Manufacturing (AM) in Pharmaceutical Sciences. The initial chapter provides the historical perspective and current scenario of AM in pharmaceuticals. The book further discusses about different 3D printing platform technologies such as FDM, SLA, SLS, SSE, Ink-jet & binder jet principles & applications in developing advanced drug delivery systems. It also covers the methodology, materials for AM and important parameters associated with these platform technologies. The book highlights the progress and practical applications of 4D-printing technology in healthcare & pharmaceuticals fraternity as well including the essence of bioprinting in pharmaceuticals. Finally, the book reviews the regulatory guidelines, perspectives, and integration of Artificial Intelligence (AI)/Machine learning (ML) in pharmaceutical AM. This book is indeed a valuable resource for students, researchers/scholars, young start-ups/entrepreneurs, and pharmaceutical professionals by providing thorough detailing about AM in Pharmaceuticals.
    Type of Medium: Online Resource
    Pages: XIV, 369 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819924042
    URL: https://doi.org/10.1007/978-981-99-2404-2
    DOI: 10.1007/978-981-99-2404-2
    DDC: 615.19
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 26
    Online Resource
    Online Resource
    Computer Aided Pharmaceutics and Drug Delivery : An Application Guide for Students and Researchers of Pharmaceutical Sciences (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmaceutical chemistry. ; Pharmacology. ; Drug delivery systems. ; Biotechnology. ; Pharmaceutics. ; Pharmacology. ; Drug Delivery. ; Biotechnology.
    Description / Table of Contents: History and Present Scenario of Computers in Pharmaceutical Research and Development.-Historical Developments on Computer Applications in Pharmaceutics -- Computer Aided Formulation Development -- Quality-by-Design in Pharmaceutical Development -- Teaching Principles of DoE as an Element of QbD for Pharmacy Students -- Computer-Assisted Manufacturing of Medicines -- Computer Aided Biopharmaceutical Characterization: Gastrointestinal Absorption Simulation and In Silico Computational Modeling -- Computer Simulation and Modeling in Pharmacokinetics and Pharmacodynamics -- Physiologicallly Based Pharmacokinetic Modelling -- Computers in Clinical Development -- Artificial Intelligence (AI) -- Robotic Automation of Pharmaceutical and Life Science Industries -- Soft Robots for the Delivery of Drugs -- Use of Computers and Internet in Scholarly Information Retrieval -- Patent Searching -- Computer Aided Drug Design (CADD) -- Quantitative Structure Property Relationship (QSPR) Modeling Applications in Formulation Development -- Modeling Approaches for Studies of Drug-Polymer Interactions in Drug Delivery Systems -- Computers in Pharmaceutical Analysis -- Telemedicine -- Bioinformatics in Drug-Design and Delivery -- Statistical Modeling Techniques -- Molecular Modelling of Nanoparticles -- Pharmaceutics Informatics: Bio/chemoinformatics in Drug Delivery -- Computer-aided Development and Testing of Human Extra-thoracic Airway Models for Inhalation Drug Delivery.
    Abstract: This book examines the role of computer-assisted techniques for discovering, designing, optimizing and manufacturing new, effective, and safe pharmaceutical formulations and drug delivery systems. The book discusses computational approaches, statistical modeling and molecular modeling for the development and safe delivery of drugs in humans. The application of concepts of QbD (Quality by Design), DoE (Design of Experiments), artificial intelligence and in silico pharmacokinetic assessment/simulation have been made a lot easier with the help of commercial software and expert systems. This title provides in-depth knowledge of such useful software with illustrations from the latest researches. The book also fills in the gap between pharmaceutics and molecular modeling at micro, meso and maro scale by covering topics such as advancements in computer-aided Drug Design (CADD), drug-polymer interactions in drug delivery systems, molecular modeling of nanoparticles and pharmaceutics/bioinformatics. This book provides abundant applications of computers in formulation designing and characterization are provided as examples, case studies and illustrations. Short reviews of software, databases and expert systems have also been added to culminate the interest of readers for novel applications in formulation development and drug delivery. Computer-aided pharmaceutics and drug delivery is an authoritative reference source for all the latest scholarly update on emerging developments in computed assisted techniques for drug designing and development. The book is ideally designed for pharmacists, medical practitioners, students and researchers. .
    Type of Medium: Online Resource
    Pages: XVII, 762 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811651809
    URL: https://doi.org/10.1007/978-981-16-5180-9
    DOI: 10.1007/978-981-16-5180-9
    DDC: 615.19
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 27
    Online Resource
    Online Resource
    Polypharmacology : Principles and Methodologies (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Neuropharmacology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Neuropharmacology.
    Description / Table of Contents: PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles -- Basics of Polypharmacology -- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C) -- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF) -- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD) -- Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD -- Anti-cancer Polypharmacology -- Cardiovascular Polypharmacology -- Neuronal Polypharmacology -- Pulmonary Polypharmacology -- Polypharmacology of Metabolic Disease -- Polypharmacology of Infectious Disease -- Polypharmacology of Inflammation -- Anti-psychotics Polypharmacology -- Anti-aging Polypharmacology -- Polypharmacology in Drug Repurposing -- Polypharmacology and Unintended Drug Promiscuity -- Polypharmacology Pharmacokinetics -- The Future of Polypharmacology -- PART II. Polypharmacology in New Drug Development: Strategies and Protocols -- Designed MTSD Discovery Process -- Designed MTSD Discovery Strategies -- Designed MTSD Discovery Technologies -- Designed MTSD Discovery Databases -- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation -- Designed MTSD Lead Identification and Optimization -- Designed MTSD Discovery Protocols -- Natural Products in MTSD Discovery -- Polypharmacology Procedures for Drug Repurposing -- Polypharmacology Procedures for Drug Promiscuity Discovery.
    Abstract: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on Polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology on Polypharmacology. This book aims to meet the needs of making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of Polypharmacology targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy. Rich in illustrations and tables to showcase readers for better understanding the concepts and technologies related to Polypharmacology; Provides comprehensive, systemic, holistic, and explicit explanations and discussion of the fundamental knowledge, background information, conceptual evolution, and updated methodology, as well as in-depth mechanisms behind the knowledge and methodology of Polypharmacology; Main emphasis on rationally designed Polypharmacology or “multi-target, single-drug (MTD)” pharmacology, which represents the major future direction of Polypharmacology and Pharmacology; Describes the clinical applications of Polypharmacology to various human diseases in the clinical and preclinical settings; Contains a wide collection of the state-of-the-art Polypharmacology technologies applicable to the designed MTD discovery and the step-by-step descriptions of drug discovery process applying Polypharmacology principles and methodologies.
    Type of Medium: Online Resource
    Pages: XXV, 856 p. 12 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031049989
    URL: https://doi.org/10.1007/978-3-031-04998-9
    DOI: 10.1007/978-3-031-04998-9
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 28
    Online Resource
    Online Resource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 29
    Online Resource
    Online Resource
    Functional Biomaterials : Drug Delivery and Biomedical Applications (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Drug delivery systems. ; Biomaterials. ; Therapeutics. ; Biology Technique. ; Genetic engineering. ; Biomedical engineering. ; Drug Delivery. ; Biomaterials. ; Therapeutics. ; Gene Delivery. ; Biomedical Materials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Polymeric Micelle in Drug Delivery Applications -- Chapter 2. pH-responsive Biomaterialsin Drug Delivery -- Chapter 3. Stimuli-responsive hydrogels in drug delivery -- Chapter 4. Polysaccharide based biomaterials for dermal applications -- Chapter 5. Biomaterials in Gene Delivery -- Chapter 6. Polymeric nanoparticles for theranostic treatment of cancer -- Chapter 7. Smart Theranostic Biomaterials for Advanced Healthcare Application -- Chapter 8. Silk Fibroin-based Biomaterials in Biomedical Applications -- Chapter 9. Biomaterial based nanofibers scaffolds in tissue engineering application -- Chapter 10. Biomedical applications of inorganic biomaterials -- Chapter 11. Synthesis Biomaterials in Biomedical Applications -- Chapter 12. 3D Printed Biomaterials in Biomedical Application -- Chapter 13. Metallic biomaterials in biomedical applications -- Chapter 14. Ceramic biomaterials in advanced biomedical applications -- Chapter 15. Hybrid Biomaterials in Drug Delivery and Biomedical Applications -- Chapter 16. Graphene-polymer composites for biomedical applications -- Chapter 17. Applications of ionic liquids in pharmaceutical sciences -- Chapter 18. Metallic Biomaterials for Medical and Dental Prosthetic Applications.
    Abstract: This book explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field. This newer and updated approach will be attractive for biomedical engineering students working on materials science in the development of novel drug delivery strategies. The book will be an important reference for researchers and professionals working on biomaterial research in the pharmaceutical and medical fields.
    Type of Medium: Online Resource
    Pages: VIII, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811671524
    URL: https://doi.org/10.1007/978-981-16-7152-4
    DOI: 10.1007/978-981-16-7152-4
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 30
    Online Resource
    Online Resource
    Actinobacteria : Microbiology to Synthetic Biology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Synthetic Biology. ; Bioinformatics. ; Drug delivery systems. ; Industrial microbiology. ; Synthetic Biology. ; Bioinformatics. ; Drug Delivery. ; Industrial Microbiology.
    Description / Table of Contents: Chapter 1. Actinomycetes: Microbiology to Systems Biology -- Chapter 2. Diversity of actinobacteria in various habitats -- Chapter 3. Traditional Screening and Genome Guided Screening of Natural Products from Actinobacteria -- Chapter 4. The relationship between actinobacteria and rice -- Chapter 5.Non-ribosomally and ribosomally synthesized bioactive peptides – NRPS and RiPPs from actinobacteria -- Chapter 6. Genome Data Mining, Chemistry and Bioactivity of Sesquiterpenes from Actinobacteria -- Chapter 7. Genome Data Mining, Chemistry and Bioactivity of Sesquiterpenes from Actinobacteria -- Chapter 8. Cloning and Heterologous expression of Natural products from Actinobacteria -- Chapter 9. Synthetic Biology and Metabolic Engineering in Actinobacteria for Natural Product Production -- Chapter 10. CRISPR ERA: CURRENT APPLICATIONS AND FUTURE PERSPECTIVES ON ACTINOBACTERIA -- Chapter 11. Uncultured Actinobacteria and Reverse engineering and Artificial Intelligence role in future -- Chapter 12. Cultivation and Diversity of Marine Actinomycetes: Molecular Approaches and Bioinformatics Tools -- Chapter 13. Antimicrobial Potential and Metabolite Profiling of Marine Actinobacteria -- Chapter 14. Pharmacology of FDA Approved Medicines from Actinobacteria.
    Abstract: This book summarizes the basics of actinobacteria, from microbiology to synthetic biology. It focuses on diversity, NRPS, sesquiterpenes, lantipeptide, bioinformatics apparatuses, cloning, CRISPR, reverse engineering, FDA supported medications, and marine actinobacteria. It also covers the latest trends in drug discovery from actinobacteria, and introduces several recently developed bioinformatics and synthetic biology tools to explore new antibiotics from actinobacteria. Many natural products such as polyketides, isoprenoids, phenazines, peptides, indolocarbarbazoles, sterols, and others have been isolated and characterized from actinobacteria. Some products are synthesized by the non-ribosomal peptide synthetases (NRPSs), polyketide synthases (PKSs), or other functional genes. Although genome sequencing has uncovered the differing qualities of these chemicals, recognizing new items and their biosynthetic pathways is still under examination. Cryptic metabolic pathways have been explored using molecular techniques or culture-dependent approaches. In recent years, researchers’ primary interest is to identify the specific conditions or agents that wake the cryptic antibiotics. Several bioinformatics and synthetic biology tools were developed to explore new antibiotics from actinobacteria. The book comprises 14 chapters with different aspects of application and utilization of actinomycetes from the microbiology; systems biology, pharmacology of natural products, bioinformatics, actinomycete and its diversity, CRISPR, artificial Intelligence, synthetic biology, metabolic engineering, expressional studies, and biosynthetic gene clusters. The book delivers useful information on actinomyces to researchers, novices in genome designing, specialists, clinicians, policymakers, and professionals.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811658358
    URL: https://doi.org/10.1007/978-981-16-5835-8
    DOI: 10.1007/978-981-16-5835-8
    DDC: 570.724
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 31
    Online Resource
    Online Resource
    Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Medicinal chemistry. ; Pharmaceutical chemistry. ; Pharmacology. ; Drug Delivery. ; Medicinal Chemistry. ; Pharmaceutics. ; Pharmacology.
    Description / Table of Contents: Part 1-Modelling of PK/PD for NPDDS -- Introduction to Nanoparticulate Drug Delivery Systems -- Nanoparticle Properties Affecting Pharmacokinetics of NPDDS -- Models Used for Biopharmaceutical Evaluation of NPDDS -- Models Used in the Pharmacokinetic Evaluation of NPDDS -- Models Used in the Pharmacodynamic Evaluation of NPDDS -- Preclinical Animal Models For Experimental Design of Pharmacokinetic Studies of NPDDS -- Pharmacokinetic Modelling Program (PKMP) -- Part 2-PK/PD for Specific Nanocarriers -- Pharmacokinetic and Pharmacodynamics of Liposomal Nanoparticles -- Pharmacokinetics of Polymer Matrix Drugs (NPDDS) -- Pharmacokinetics of Long-Circulating NPDDS -- Metallic Gold Nanoparticles in vivo Pharmacokinetics and X-ray Contrast imaging Studies -- Muco-adhesive NPDDS In Vitro and Pharmacokinetics Studies -- Pharmacokinetic and Tissue Distribution Study of Solid Lipid Nanoparticles -- Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles -- PKPD of PLGA-PEG-PLGA Triblock CoPolymeric Micelles -- Part 3-PKPD in Diseased Conditions for NPDDS -- Bridging Bio-Nanoscience and Cancer Nanomedicine -- Clearance Pathways and Tumor Targeting of Imaging Nanoparticles for Diagnostics -- PLGA Nanoparticles for Oral Delivery-Nephrotoxicity and Pharmacokinetic Studies -- Pharmacokinetics of Nanoparticle Systems for Pulmonary Delivery -- In vivo Biodistribution and Pharmacokinetic Studies of NPDDS for Brain Targeting -- Enhanced Bioavailability and Intestinal Uptake Nanoparticles After Oral Delivery -- Nanoparticle Pharmacokinetic Profiling In Vivo Using Magnetic Resonance Imaging.
    Abstract: A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems. No other consolidated published reference discusses the PK/PD study of nanoparticle drug delivery systems. This book discusses the advantages of nanoparticle drug delivery systems (NPDDS) in enhancing the pharmacokinetics of many drugs that are not easily metabolized or that obtain the desired therapeutic effect with minimum toxicity. The authors provide an overview of biodistribution with a focus on polymer and lipid nanoparticles. This thorough reference is divided into three parts: Modelling, Specific carries and their potential to treat specific diseases.
    Type of Medium: Online Resource
    Pages: XIII, 438 p. 102 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030833954
    URL: https://doi.org/10.1007/978-3-030-83395-4
    DOI: 10.1007/978-3-030-83395-4
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 32
    Online Resource
    Online Resource
    Peptide Therapeutics : Fundamentals of Design, Development, and Delivery (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmaceutical chemistry. ; Drug delivery systems. ; Drugs Design. ; Pharmacology. ; Pharmacy. ; Proteins Synthesis. ; Pharmaceutics. ; Drug Delivery. ; Structure-Based Drug Design. ; Pharmacology. ; Pharmacy. ; Protein Synthesis and Translation.
    Description / Table of Contents: Basic Concepts of Design of Peptide based Therapeutics -- Computational Methods in Peptide Based Drug Design -- Synthesis, Purification, and Characterization of Linear and Cyclic Peptides -- Large Scale Synthesis of Peptides, Manufacturing Peptide Therapeutics -- Stability of Peptides -- Peptide Delivery Systems -- Liposomes and Nanoparticle Formulations for Peptide Delivery -- Delivery of Peptides Across the Blood-brain Barrier (BBB) -- Peptide Therapeutics Regulatory Considerations.
    Abstract: This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. The chapters are arranged in a linear fashion. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. Rather than covering extensive literature, the book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides. The book has nine chapters, and each chapter can be read as an independent unit on a particular concept.
    Type of Medium: Online Resource
    Pages: IX, 317 p. 52 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031045448
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 47
    URL: https://doi.org/10.1007/978-3-031-04544-8
    DOI: 10.1007/978-3-031-04544-8
    DDC: 615.19
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 33
    Online Resource
    Online Resource
    Drug Delivery to the Brain : Physiological Concepts, Methodologies and Approaches (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Drug delivery systems. ; Neuropharmacology. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Drug Delivery. ; Neuropharmacology. ; Biomedical Research. ; Pharmaceutics.
    Description / Table of Contents: Part I-Physiology and Basic Principles of Drug Handling for the CNS -- Anatomy and Physiology of the Blood Brain Barriers -- Drug Delivery to the Brain: Integrating Neuroscience, Physiology, and Brain Barriers Science -- Brain Delivery of Therapeutics via Transcytosis: Types and Mechanisms of Vesicle-Mediated Transport Across the BBB -- Brain- Arachnoid Barrier as an Important Clearance Pathway from CSF -- BBB Pharmacoproteomics: Quantitative Targeted Absolute Proteomics (QTAP): Species Differences -- Drug Metabolism at the BBB and the BCFSB -- PART II-PK Concepts and Methods for Studying CNS Drug Delivery -- Pharmacokinetics Concepts in Brain Drug Delivery -- In Vitro Models of CNS Barriers -- Human In Vitro BBB Models Derived from Pluripotent Stem Cells -- In situ and In vivo Animal Models -- Principles of PET and Its Role in Understanding Drug Delivery to the Brain -- Prediction of CNS PK and PD Using Translational Research Approaches -- Part III-Industrial Approaches for Investigation of Potential CNS Drugs -- Drug Discovery Methods for Studying Brain Drug Delivery and Distribution -- Prediction of Drug Exposure in the Brain From the Chemical Structure -- Integrated Approach to Optimizing CNS Penetration in Drug Discovery -- Part IV: Strategies for Improved CNS Drug Delivery -- Intranasal Drug Delivery to the Brain -- Blood to Brain Drug Delivery Using Nanocarriers -- Enhancing CNS Exposure Through Brain Endothelial Cell RMT-Exploiting the Transferrin Receptor at the BBB -- Therapeutic Osmotic Modification of the BBB in the Treatment of CNS Pathologies -- Biophysical Perspectives on BBB Permeability Enhancement by Ultrasound and Microbubbles for Targeted Drug Delivery in the Clinical Setting -- Optimization of Blood Brain Barrier Opening With Focused Ultrasound-The Animal Perspective -- CNS Gene Therapy Using Adeno-Associated Virus (AAV) Vectors -- Part V-CNS Drug Delivery in Disease Conditions -- Disease Influence on BBB Transport in Neurodegeneration and Neuroinflammation -- Enhancing Drug Delivery in the Setting of Stroke and Brain Injury -- Drug Delivery to tumor Metastases in the Brain-(Including PK PD Free Fraction Active Conc.) -- Drug Delivery to Primary Tumors in the Brain-(Including PK PD Free Fraction Active Conc.) -- Appendix:CNS Anatomy, Function, Vasculature and Fluid Exchange: Primer for Drug Delivery Scientists.
    Abstract: The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, drug industry perspectives, and a primer on neuroanatomy and physiological considerations written specifically for drug delivery scientists. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications. .
    Type of Medium: Online Resource
    Pages: XXI, 806 p. 199 illus., 179 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030887735
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 33
    URL: https://doi.org/10.1007/978-3-030-88773-5
    DOI: 10.1007/978-3-030-88773-5
    DDC: 615.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 34
    Online Resource
    Online Resource
    New Trends in Macromolecular and Supramolecular Chemistry for Biological Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Drug delivery systems. ; Regenerative medicine. ; Biomedical Research. ; Pharmacology. ; Drug Delivery. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Approaches Towards Synthetic Signal Transduction in Phospholipid Bilayers -- Development of Novel Versatile Theranostic Platforms Based on Titanate Nanotubes: Towards Safe Nanocarriers for Biomedical Applications -- Metal-organic Framework—Polymer Mixed-Matrix Membranes -- Insights into Adaptive Selforganized Supramolecular Structures from Molecular Modeling and Visualization -- Self-Assembled Metallacages as Drug Delivery Systems: Design Concepts and Challenge -- Functional Microporous Polymer Networks: Synthesis and Applications -- A Story on Carbon Dioxide and its Hydration -- Inverse Design and Hierarchical Multiscale Modelling of Biological Matter -- DNA-Directed Self-assembly of Macromolecular Structures -- Luminescent Complexes and their Assemblies : from Understanding to Artificial Virus -- Tailor-Made Polymers and Nanoparticles for Applications in Nanomedicine -- Squalene-based Nanomedicines : An Original and Efficient Approach for the Treatment of Neurological Disorders without Crossing the Blood-Brain Barrier -- Biodegradable Nanoparticles for Specific Drug Transport -- Multivalent rotaxanes designed as antibiofilm agents -- Measuring Ionic Transport through Lipid Bilayers -- Polymeric Carriers for Transporting Nucleic Acids - Contributions to the Field -- Smart Polymeric Materials for Drug Delivery -- Supramolecular Guanosine-quadruplex Hydrogels and Hydrogel Composites for Cell Growth Applications -- Hydrogelation of Chitosan with Monoaldehydes towards Biomaterials with Tuned Properties -- Inorganic Nanoarticles as Free Radical Scavengers -- A Microbiological Epilogue - Nosocomial Infections -- Molecular Dynamic Simulations and In Silico Analysis of Supramolecular Self-Assembled Structures -- Validation of the Non Toxicity of Non Viral Genetic -- Kinetics Transport of Ions/Water Through Nano-Scale Channels : Review And Update.
    Abstract: This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations. The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.
    Type of Medium: Online Resource
    Pages: XII, 371 p. 174 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030574567
    URL: https://doi.org/10.1007/978-3-030-57456-7
    DOI: 10.1007/978-3-030-57456-7
    DDC: 610.72
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 35
    Online Resource
    Online Resource
    Smart Nanomaterials in Biomedical Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Nanomedicine. ; Drug delivery systems. ; Nanotechnology. ; Cancer Nanotechnology. ; Drug Delivery. ; Nanotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Foreword -- Preface -- Introduction to active smart nanomaterials for biomedical applications -- Cancer cell sensing and therapy using affinity tag-conjugated gold nanoparticles -- Gold nanoparticles enlighten the future of cancer theranostics -- Recent advances in hydrogels smart drug delivery systems -- Carbon-based nanomaterials for biomedical applications -- A new era of cancer treatment: carbon nanotubes as drug delivery tools -- pH- and ion-sensitive materials for control drug delivery -- Thermo-responsive polymers and their application as smart biomaterias -- Redox-responsive polymers and their application in drug delivery systems -- Recent strategies to explore the biomedical applications of nanocellulose -- Tissue engineering using cellulose nanofibrils as Scaffold material -- Use of solidlipid nanoparticles to improve the oral bioavailability of poor soluble drugs -- Applications of dendrimers in drug delivery systems -- Liposomes for drug delivery: progress and problems -- Cubosome nanoparticles for enhanced delivery of anticancer drug -- Layer-by-Layer assemblies for cancer diagnosis and treatment -- Polymeric micelles for drug delivery -- Role of plant-based materials/gums in developing drug delivery systems -- Ethosomes: A novel tool for drug delivery through the skin -- Niosomes as nanoparticular drug carriers: fundamentals and recent applications -- Graphene oxide nanosheets used in photothermal therapy -- Metal doped carbon dots used in bio-imaging and cancer therapy -- Bibliography -- Glossary -- Index.
    Abstract: With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.
    Type of Medium: Online Resource
    Pages: XIII, 600 p. 131 illus., 122 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030842628
    Series Statement: Nanotechnology in the Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-84262-8
    DOI: 10.1007/978-3-030-84262-8
    DDC: 616.994
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 36
    Online Resource
    Online Resource
    Medicinal Plants for Lung Diseases : A Pharmacological and Immunological Perspective (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Human physiology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Human Physiology. ; Pharmaceutics. ; Drug Delivery.
    Description / Table of Contents: Chapter 1. Immunopathology of respiratory diseases -- Chapter 2. Introduction to Chronic Respiratory Diseases: A Pressing Need for Novel Therapeutic Approaches -- Chapter 3. Role of Indian Herbal Medicine in the treatment of Pulmonary Diseases -- Chapter 4. Asthma-induced inflammatory responses and reversal by botanicals -- Chapter 5. Medicinal plants in targeting asthma -- Chapter 6. Incipient need of medicinal plants in targeting chronic obstructive pulmonary disease -- Chapter 7. Utilization of Natural Compounds for Treatment of Tuberculosis-I -- Chapter 8. Medicinal plants in the treatment of Tuberculosis-II -- Chapter 9. Medicinal Plants in the Treatment of tuberculosis-III -- Chapter 10.Natural compounds as versatile potential therapeutic agents of lung cancer -- Chapter 11. Exploring the potential of medicinal plants in Lung Cancer -- Chapter 12. Effect of Medicinal Plants against Lung Cancer -- Chapter 13. Medicinal Plants used in the treatment of pulmonary hypertension- I -- Chapter 14. Medicinal Plants used in the treatment of pulmonary hypertension-II -- Chapter 15. Herbal bioactives for the treatment of idiopathic pulmonary fibrosis -- Chapter 16. Medicinal Plants targeting Bronchitis -- Chapter 17. Role of medicinal plants in the treatment of pulmonary edema -- Chapter 18. Medicinal Plants Used in the Treatment of Influenza a Virus Infections -- Chapter 19. Medicinal Plants used in the treatment of influenza A virus infections -- Chapter 20. COVID-19 pandemic panic: prophylactic as well as therapeutic management with traditional ethnic phytopharmaceuticals with challenging nano-spray inhaler and advanced drug delivery system -- Chapter 21. Targeting SARS-CoV2 novel corona (COVID-19) virus infection using medicinal plants -- Chapter 22. Promising plant based bioactive natural products in combating SARS-CoV2 novel corona (COVID-19) virus infection -- Chapter 23. Medicinal plant based advanced drug delivery system for the treatment of chronic lung diseases -- Chapter 24. Medicinal Plant Based Advanced Drug Delivery System for the Treatment of Chronic Lung Diseases -- Chapter 25. Application of nanodrugs derived from active metabolites of medicinal plants for the treatment of inflammatory and lung diseases: Recent advances.
    Abstract: This book summarizes experimentally-supported research on the therapeutic efficacy of plant extracts and their constituents on a range of respiratory diseases including infections. It discusses the pharmacological, cellular and molecular factors involved in the pathogenies of respiratory diseases and their modulation by plant-derived compounds. Additionally, it underlines the growing relevance of medicinal plant-based advanced drug delivery systems for treating lung diseases providing maximal therapeutic efficacy with better patient compliance. Overall, this comprehensive book is a blend of translational, biological, chemical and drug delivery aspects of medicinal plants employed in targeting respiratory diseases and attracts a range of audiences including physiochemist, translational and clinical researchers working in the field of respiratory diseases.
    Type of Medium: Online Resource
    Pages: XIV, 622 p. 159 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813368507
    URL: https://doi.org/10.1007/978-981-33-6850-7
    DOI: 10.1007/978-981-33-6850-7
    DDC: 612
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 37
    Online Resource
    Online Resource
    Nanotechnology Applications in Health and Environmental Sciences (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Microbiology. ; Nanotechnology. ; Plant biotechnology. ; Bioremediation. ; Drug delivery systems. ; Microbiology. ; Nanotechnology. ; Plant Biotechnology. ; Environmental Biotechnology. ; Drug Delivery.
    Description / Table of Contents: Preface -- Diverse Manifolds of Biogenic Nanoparticles in Synthesis, Characterization and Applications -- Impact of Nanoparticles on Human Microbiota -- In-Vitro Applications of Nanoparticles -- Nanoparticles for Anticancer Drug Delivery -- Application of Nanotechnology in the Treatment of Microbial Infections -- Metal Organic Framework: Applications in Nanomedicine -- Recent Advances in Nanomaterial-Based Diagnosis and Treatment -- Nanobiosensors for Biomedical Applications -- Emerging Role of Nanomaterial Assisted Bio-Sensors for Circulating Tumor Cells Detection -- Advanced Functional Polymers for Biomedical Applications -- SERS Sensor Applications in Environmental Analysis and Biotechnology -- Design and Creation of Micro and Nano Environment in Regenerative and Restorative Medicine -- Presenting and Treating Bone Infections Using Silver-Ion Containing Nano-Hydroxyapatite -- Trace Element Containing Nano-HAp for Preventing Musculoskeletal Infections -- Biotechnological Approaches in Maintenance of a Healthy Immune System for Protection Against Diseases -- Production and Characterization of Antibiotic-Containing Nano-Calcium Phosphates -- Lantibiotics Nanotechnology, Bioengineering and Biotechnology -- Microbial Biotechnology and Postmortem Diagnosis -- Clean-Up and Pollution with Nanoparticles: An Environmental Dillemma -- Environmental Myco-Nanobiotechnology and Fungal Bioremediation -- Application of Nanotechnology in Detection and Diagnosis of Plant Diseases -- Index.
    Abstract: Nanoscience and nanotechnologies are a major factor leading in our understanding of nature. Nanotechnology can be generally defined as creation and use of nano-sized systems, devices, and structures which have special functions or properties because of their small size. This volume on Nanotechnology Applications in Health and Environmental Sciences focuses on biotechnological and environmental applications of nanomaterials. It covers popular and various nanomedical topics such as oncology, genetics, and reconstructive medicine. Additionally, many chapters give leading-edge information on nano-sensor applications and usage in specific disciplines. Also, two chapters on novel subjects have been included on antibiotics and microbiota. This book should be useful for nanotechnologists, microbiologists, and researchers interested in nanomedicine and nano-biotechnology, as well as environmental nanotechnology. .
    Type of Medium: Online Resource
    Pages: XIV, 439 p. 77 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030644109
    Series Statement: Nanotechnology in the Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-64410-9
    DOI: 10.1007/978-3-030-64410-9
    DDC: 579
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 38
    Online Resource
    Online Resource
    Drug Discovery and Drug Development : The Indian Narrative (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Drug delivery systems. ; Biologicals. ; Biopharmaceutics. ; Toxicology. ; Biotechnology. ; Pharmacology. ; Drug Delivery. ; Biologics. ; Toxicology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Traditional Medical System (TMS) for Sustainable Healthcare in India -- Chapter 2. Modern Drug Discovery and Development for TB- The India Narrative -- Chapter 3. Indian Discovery Effort in the Quest of Novel Antibiotics -- Chapter 4. New Drug Discovery and Development in India to Counter Malaria -- Chapter 5. Modern Drug Discovery and Development in the area of Leishmaniasis -- Chapter 6. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part I – Introduction to Diabetes and Prevalence in India -- Chapter 7. Modern Drug Discovery and Development: Diabetes and lifestyle disorder Part II Type 2 Diabetes Mellitus: Marketed drugs and mechanisms -- Chapter 8. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part III Anti-diabetes research in India: Contributions from industrial organizations -- Chapter 9. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part IV Indian Academia Tryst with Cardio-metabolic Drug Discovery and Development -- Chapter 10. Modern drug discovery and development in the area of Cancer: Indian context -- Chapter 11. Biopharmaceutical development in India: recommendations on collaboration and innovation to enable affordable healthcare -- Chapter 12. Regulatory requirements and Quality Standards in India’s Clinical Trials Journey -- Chapter 13. Indian Pharma Perspective: New Drug Discovery and Development- Indian Pharmaceutical Industry.
    Abstract: Over the years, India has attained a prominent global position in the manufacture of Generic Drugs. This success can be attributed to its synthetic organic chemistry and chemical engineering strengths, nurtured by the timely policies of the Government of India. However, breakthrough successes in New Drug Discovery have remained elusive, despite the brilliant and sustained efforts of many Indian researchers and Pharma establishments. The Indian National Science Academy thought it appropriate to document India’s New Drug Discovery Research (NDDR) journey to date. Gathering contributions from prominent researchers in the Indian Pharma Industry and Academia, this book highlights their efforts, achievements, and the status quo of Indian NDDR. .
    Type of Medium: Online Resource
    Pages: XIII, 376 p. 191 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811580024
    URL: https://doi.org/10.1007/978-981-15-8002-4
    DOI: 10.1007/978-981-15-8002-4
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 39
    Online Resource
    Online Resource
    Molecularly Imprinted Polymers as Advanced Drug Delivery Systems : Synthesis, Character and Application (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Drug delivery systems. ; Biotechnology. ; Pharmacology. ; Drug Delivery. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Synthetic Strategies for the Generation of Molecularly Imprinted Polymers -- Chapter 3. Special Control by Molecular Imprinting Materials-zero-order Sustained Release, Enantioselective MIPs and Self-regulated Drug Delivery Microdevices -- Chapter 4. Water Compatible Molecularly Imprinted Polymers -- Chapter 5. Stimuli Responsive Imprinted DDS -- Chapter 6. MIP as Drug Delivery Systems for Dermal Delivery -- Chapter 7. MIP as Drug Delivery Systems of Anticancer Agents -- Chapter 8. MIP as Dug Delivery Systems of Ophthalmic Drugs -- Chapter 9. MIP as Drug Delivery Systems for Special Application -- Chapter 10. Outlook.
    Abstract: This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives.
    Type of Medium: Online Resource
    Pages: VII, 216 p. 108 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602276
    URL: https://doi.org/10.1007/978-981-16-0227-6
    DOI: 10.1007/978-981-16-0227-6
    DDC: 615
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 40
    Online Resource
    Online Resource
    Stem Cells : Latest Advances (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Developmental biology. ; Cancer. ; Drug delivery systems. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Developmental Biology and Stem Cells. ; Cancer Stem Cells. ; Drug Delivery.
    Description / Table of Contents: Micro-Electrode-Arrays: A valuable tool to analyze stem cell derived cardiomyocytes -- CD34+ STEM CELLS AND REGENERATIVE MEDICINE -- Mesenchymal-Hematopoietic Stem Cell Axis: Applications for Induction of Hematopoietic Chimerism and Therapies for Malignancies -- Mesenchymal stem cell-derived secretome: a new remedy for the treatment of autoimmune and inflammatory diseases -- Cardiac regenerative therapy in diabetes: challenges and potential therapeutics -- Macrophage Response to Biomaterials in Cardiovascular Applications -- Evolution of stem cells in cardio-regenerative therapy -- Stem cell-based cardiac regeneration: is there a place for optimism in the future? -- Dental mesenchymal stem/progenitor cells: A new prospect in regenerative medicine -- Stem cell-based tissue engineering for functional enamel and dentin/pulp complex: a potential alternative to the restorative therapies -- Cell and stem cell-based therapies for liver defects: Recent advances and future strategies -- Stem cells: a renewable source of pancreatic β-cells and future for diabetes treatment -- Induced pluripotent stem cells in pediatric research and clinical translation -- Maturity of Pluripotent Stem Cell-Derived Cardiomyocytes and Future Perspectives for Regenerative Medicine -- Availability of pluripotent stem cells from normal cells in cancer science -- Index.
    Abstract: In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research. The book covers many aspects of stem cell-based therapy and the progress made toward stem cell therapy for liver, ocular, and cardiovascular diseases as well as cancer. This volume serves as a continuation of Prof. Khawaja Husnain Haider’s previously edited books pertaining to stem cells-based therapnostics. This is an ideal book for researchers involved in drug development as well as regenerative medicine and stem cell-based therapy. The secondary audience includes graduate and postgraduate medical students, doctors, cellular pharmacology, drug industry, and researchers involved in using stem cells as ex-vivo disease models for drug development.
    Type of Medium: Online Resource
    Pages: X, 255 p. 38 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030770525
    URL: https://doi.org/10.1007/978-3-030-77052-5
    DOI: 10.1007/978-3-030-77052-5
    DDC: 571.6
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
  • 41
    Online Resource
    Online Resource
    Ophthalmic Product Development : From Bench to Bedside (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmaceutical chemistry. ; Ophthalmology. ; Drug delivery systems. ; Drugs Design. ; Pharmaceutics. ; Ophthalmology. ; Drug Delivery. ; Structure-Based Drug Design.
    Description / Table of Contents: Introduction and History of Ophthalmic Product Development -- Ocular Surface Anatomy and Physiology: Impact on Product Development -- Anatomy and Physiology of the Anterior Chamber – Impact on Product Development -- Back of the eye anatomy & physiology – Impact on product development -- Physicochemical and Biological Fundamentals for Drug Delivery to the Eye -- Topical Ophthalmic Dosage Form Development – Key Components and Critical Quality Attributes -- Intra-ocular Injectable Dosage Form Development -- Microbiological Considerations for Ophthalmic Products – Sterility, Endotoxin Limits and Preservatives -- Packaging Development – Multi-dose container closure for preservative free products, extractable/leachables from packaging, new technologies -- Liquid ophthalmic drug products – physicochemical properties, formulations and manufacturing considerations -- Emulsions for topical eye delivery: state of the art and future perspectives -- Emulsions for topical eye delivery: state of the art and future perspectives -- Microparticle Products For The Eye - preformulation, formulation, and manufacturing considerations -- NANOPARTICLE PRODUCTS FOR THE EYE: preformulation, formulation and manufacturing considerations -- Advanced Hydrogel Formulations for the Eye -- Ophthalmic Product Development for Biologics -- Implantable Devices to Treat Ophthalmic Conditions –Drug Delivery Systems -- Development of Artificial Tears Products for Ocular Conditions -- Approval of Topical Ophthalmic Generic Products in the US – Simple to Complex Dosage Forms and Establishing Equivalency -- The development and commercialization of sustained-release ocular drug delivery technologies -- Manufacturing considerations and challenges for AAV Ocular Gene Therapy -- Transcorneal Kinetics of Topical Drugs and Nanoparticles.
    Abstract: This is a comprehensive textbook addressing the unique aspects of drug development for ophthalmic use. Beginning with a perspective on anatomy and physiology of the eye, the book provides a critical appraisal of principles that underlie ocular drug product development. The coverage encompasses topical and intraocular formulations, small molecules and biologics (including protein and gene therapies), conventional formulations (including solutions, suspensions, and emulsions), novel formulations (including nanoparticles, microparticles, and hydrogels), devices, and specialty products. Critical elements such as pharmacokinetics, influence of formulation technologies and ingredients, as well as impact of disease conditions on products development are addressed. Products intended for both the front and the back of the eye are discussed with an eye towards future advances.
    Type of Medium: Online Resource
    Pages: IX, 650 p. 126 illus., 105 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030763671
    Series Statement: AAPS Advances in the Pharmaceutical Sciences Series, 37
    URL: https://doi.org/10.1007/978-3-030-76367-1
    DOI: 10.1007/978-3-030-76367-1
    DDC: 615.19
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    E-BOOKS (AWI ONLY)
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...