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  • Books  (33)
  • Human behavior.  (13)
  • Neurological Disorders.  (12)
  • Medical genetics.  (8)
  • 612.8  (33)
  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Neurology . ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Neuroscience. ; Neurology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Description / Table of Contents: Sleep: Basic and Historical Aspects -- Sleep: Findings in Invertebrates and Lower Vertebrates -- Sleep: Evolutionary and Adaptive Changes in Birds and Mammals -- Sleep Loss: What Does it do to our Brain and Body -- Sleep: Neural Optimization as An Ultimate Function for Memory Consolidation -- Sleep: Disorders and Clinical Implications.
    Abstract: This book discusses the evolution of sleep and its possible function in the higher invertebrates and vertebrates, including humans. It describes the current concept of sleep and its functions, based on research on the mammalian system. To date, electrophysiological recordings of the brain waves, muscle activity, and eye movements are the only tools available for characterizing the sleep architecture in the majority of animals. In mammals and birds, only two distinct types of sleep are found – non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. Since the discovery of REM sleep, studies have been performed to understand the purpose of the two distinct sleep states in higher vertebrates (birds and mammals), and how REM sleep was evolved. The book summarizes the role of both REM and NREM sleep in the proper functioning of the brain and body. It covers various aspects of the role of sleep in important physiological processes, including memory consolidation, induction of synaptic plasticity, energy restoration, enhancing immune response, and maturation of neuronal circuitries during early life. Lastly, the book reviews the effects of chronic/acute sleep deprivation on memory consolidation, obesity, and the immune system in animal models and humans.
    Type of Medium: Online Resource
    Pages: XIV, 118 p. 30 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811571756
    DDC: 612.8
    Language: English
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  • 2
    Keywords: Neurosciences. ; Cognitive neuroscience. ; Psychobiology. ; Human behavior. ; Sociology. ; Neuroscience. ; Cognitive Neuroscience. ; Behavioral Neuroscience. ; Sociology.
    Description / Table of Contents: Molecular imaging of the human emotion circuit -- The neurocognitive mechanisms of unconscious emotional responses -- Social and Affective Neuroscience of Embodiment -- The neuroscience of beauty -- Mirror Neurons … in action: ERPs and neuroimaging evidence -- Sex differences in social cognition -- Development of morality and emotional processing -- Trust in Social Interaction: From Dyads to Civilizations -- The time has come to be mindwanderful: Mind wandering and the intuitive psychology mode -- Social Cognition development and socio affective dysfunction in childhood and adolescence -- Clinical neuroscience meets second-person neuropsychiatry -- EEG and ERPs in the study of Language and Social Knowledge -- fMRI and fNIRS methods for social brain studies: hyperscanning possibilities -- Modulating the Social and Affective Brain with transcranial stimulation techniques -- What our eyes can tell us about our social and affective brain? -- Facial EMG – Investigating the interplay of facial muscles and emotions.
    Abstract: This Open Access book presents the current state of the art knowledge on social and affective neuroscience based on empirical findings. This volume is divided into several sections first guiding the reader through important theoretical topics within affective neuroscience, social neuroscience and moral emotions, and clinical neuroscience. Each chapter addresses everyday social interactions and various aspects of social interactions from a different angle taking the reader on a diverse journey. The last section of the book is of methodological nature. Basic information is presented for the reader to learn about common methodologies used in neuroscience alongside advanced input to deepen the understanding and usability of these methods in social and affective neuroscience for more experienced readers.
    Type of Medium: Online Resource
    Pages: XXXIII, 302 p. 55 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031086519
    DDC: 612.8
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Semiotics. ; Communication. ; Ethnology. ; Social sciences. ; Humanities. ; Behavioral Neuroscience. ; Semiotics. ; Media and Communication. ; Ethnography. ; Humanities and Social Sciences.
    Description / Table of Contents: Chapter 1: Bateson, Cybernetics, and Nonverbal Communication -- Chapter 2: Analog and Digital Communication, and Similar Contrasts -- Chapter3: The Slash Mark: Gregory Bateson’s Cybernetic Semiotic -- Chapter4: Intention Movements and Peacemaking Ceremonies -- Chapter5: Relational Communication in Octopus -- Chapter6: Cuban Missile Crisis -- Chapter7: False and True Lessons from the Cuban Missile Crisis -- Chapter8: A Level too Low.
    Abstract: This book develops Gregory Bateson’s ideas regarding “communication about relationship” in animals and human beings, and even nations. It bases itself on Bateson’s theory of relational communication, as he described it in the zoosemiotics of octopus, mammals, birds, and human beings. This theory includes, for example, the roles of metaphor, play, analog and digital communication, metacommunication, and Laws of Form. It is organized around a letter from Gregory Bateson to his fellow cybernetic thinker Warren McCulloch at the time of the Cuban Missile Crisis. In this letter Bateson argued that what we would today call zoosemiotics, including Bateson’s own (previously unpublished) octopus research, should be made a basis for understanding the relationship between the two blocs of the Cold War. Accordingly the book shows how Bateson understood interactive processes in the biosemiotics of conflict and peacemaking, which are analyzed using examples from recent animal studies, from primate studies, and from cultural anthropology. The Missile Crisis itself is described in terms of Bateson’s critique of game theory which he felt should be modified by an understanding of the zoosemiotics of relational communication. The book also includes a previously unpublished piece by Gregory Bateson on wolf behavior and metaphor/ abduction.
    Type of Medium: Online Resource
    Pages: XIX, 189 p. 7 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030521011
    Series Statement: Biosemiotics, 20
    DDC: 612.8
    Language: English
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  • 4
    Keywords: Neurosciences. ; Neurology . ; Medical genetics. ; Neuroscience. ; Neurology. ; Medical Genetics.
    Description / Table of Contents: 1. Behavioural variant FTD: recent advances in the diagnosis and understanding of the disorder -- 2. The neuropsychiatry of frontotemporal dementia -- 3. Nosology and Neuropathology of Language in Primary Progressive Aphasia -- 4. Measuring Behavior and Cognition in FTLD -- 5. Clinical update on C9orf72: FTD, ALS and beyond -- 6. Clinical aspects of familial FTLD associated with MAPT and GRN mutations -- 7. Neuroimaging in Frontotemporal Lobar Degeneration -- 8. The FTD Prevention Initiative - linking together genetic FTD cohort studies -- 9. Fluid Biomarkers of Frontotemporal Lobar Degeneration -- 10. Cross-cultural perspectives on frontotemporal degeneration -- 11. Clinical characteristics and Neuropathology of PSP, CBD and Related 4R-Tauopathies -- 12. Tau protein and frontotemporal dementias -- 13. FTLD-TDP pathological subtypes: clinical and mechanistic significance -- 14. Lysosomal dysfunction as a pathogenic mechanism in FTD: Evidence from PGRN and TMEM106B genetics and biology -- 15. Future trends in understanding the pathological role of TDP-43 and FUS proteins -- 16. Description of a new data resource for FTD including multiomic data on human post mortem brain (MAPT, GRN, C9orf72), matching mouse models and iPS models -- 17. Mendelian and sporadic FTD: avenues from genetics to disease pathways through in-silico prediction and modeling -- 18. FTLD treatment: Current Practice and Future Possibilities.
    Abstract: Under the name of Frontotemporal Dementias (FTD) numerous hereditary and sporadic disorders are listed. FTD may take away speech and language, social skills and ethical judgement, wishes and will, empathy and emotions; it may also impair motor functions. FTD may affect men and women in midlife or during old age leading to the demolition of the uniqueness of the human mind. In the last decade of the 20th century and in the first two decades of the 21st century, progress in the understanding of clinical, neuropathological, biochemical, and genetic aspects of FTD has accelerated. The novel awareness about FTD has directed young generations of researchers toward the study of this complex group of disorders. This Volume has been formulated with the participation of some of the leading scientists who have contributed to the development of knowledge in the clinical and basic science arenas. It captures the current central elements that are relevant to an up-to-date understanding of causes and pathogenesis of multiple forms of FTD. The volume is an opus that represents a distillation of the work of many scientists and addresses the current directions in the study of one of the most complex groups of diseases. In view of its structure, the book could also be used as a textbook, that offers both a broad and deep analysis of major areas in FTD. This book, planned by the International Society for Frontotemporal Dementias, is distinctive as it opens a window to a wide landscape about the biology of FTD. Thus, the book represents a moment of reflection on the present state of our knowledge of FTD and a collective vision toward scientific progress. The authors of each chapter share their knowledge and vision aimed at reducing the suffering which is caused by FTD.
    Type of Medium: Online Resource
    Pages: X, 320 p. 46 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030511401
    Series Statement: Advances in Experimental Medicine and Biology, 1281
    DDC: 612.8
    Language: English
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  • 5
    Keywords: Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Abstract: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Type of Medium: Online Resource
    Pages: XV, 624 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676062
    DDC: 612.8
    Language: English
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  • 6
    Keywords: Neurosciences. ; Materials Analysis. ; Imaging systems. ; Nervous system Diseases. ; Nervous system Radiography. ; Neuroscience. ; Imaging Techniques. ; Neurological Disorders. ; Neuroradiology.
    Description / Table of Contents: Optical coherence tomography in brain gliomas detection and peritumoral white matter state evaluation -- Two Photon Fluorescence Lifetime Imaging of Reduced nicotinamide adenine dinucleotide in Brain Research -- Types of Raman Scattering Techniques for Neurodegenerative Diseases -- Drosophila brain advanced multiphoton imaging -- Myelin imaging -- Brainbow: Principle, Technique and Applications -- Photoacoustic Imaging of Brain -- Photodynamic therapy of brain diseases -- Advanced Magnetic Resonance Imaging (MRI) of Brain -- Indirect imaging -- Multimodal Noninvasive Imaging Strategies for Clinically Monitoring Degenerative Disorders of the Brain -- Machine learning approach in brain imaging -- Transgenic Brain mapping Techniques in Drosophila melanogaster -- Behavioural phenotyping to study cognitive and non-cognitive symptoms in the rodent model of Alzheimer's disease.
    Abstract: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.
    Type of Medium: Online Resource
    Pages: XII, 257 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913525
    DDC: 612.8
    Language: English
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  • 7
    Keywords: Neurosciences. ; Nervous system Diseases. ; Neurology . ; Neurophysiology. ; Neuropsychology. ; Neurons. ; Neuroscience. ; Neurological Disorders. ; Neurology. ; Neurophysiology. ; Neuropsychology. ; Cellular Neuroscience.
    Description / Table of Contents: Introduction: Neuroglia in psychiatric disorders -- Chapter 1. Astrocytes: The housekeepers and guardians of the CNS -- Chapter 2. Principles of astrogliopathology -- Chapter 3. Morphological appearance of astroglia in neuropsychiatric disorders -- Chapter 4. Astrocytes and neurotransmission: Glutamate and GABA in cognitive and mood disorders -- Chapter 5. Astroglia in bipolar disorder -- Chapter 6. Astroglia abnormalities in mood disorders -- Chapter 7. Astroglia in major depression and suicide -- Chapter 8. Neuroglia in Schizophrenia -- Chapter 9. Glutamate turnover in Schizophrenia -- Chapter 10. Astroglia and dopanime transmission in Schizophrenia -- Chapter 11. Kynurenic acid in Schyzophrenia -- Chapter 12. Astrocytes in addictive disorders -- Chapter 13. Astroglia in the vulnerability and maintenance of alcohol dependence -- Chapter 14. Astroglia in response to stress -- Chapter 15. Astroglia and Obsessive compulsive disorder -- Chapter 16. Astrocytes in regulation of food intake -- Chapter 17. Astrocytes in anorexia nervosa -- Chapter 18. Astroglial serotonin receptors as the central target of classic antidepressants -- Chapter 19. Lithium targets astrocytes -- Epilogue.
    Abstract: This contributed volume discusses the multiple roles of astrocytes, which determine the progression and outcome of neuropsychiatric diseases. This emerging area of study examines the ways in which astrocytes are involved in various aspects of disease initiation, progression and resolution. This monograph aims to integrate the body of information that has accumulated in recent years revealing the active role of astrocytes in neuropsychiatric pathology and in psychiatric disorders. Understanding roles of astrocytes in pathology will provide new targets for medical intervention and aid the development of much needed therapeutics. This book will be valuable for researchers and workers in the fields of neurobiology, neurology, and psychiatry, as well as fill the need for a textbook used in advanced courses/graduate seminars in glial pathophysiology.
    Type of Medium: Online Resource
    Pages: VI, 377 p. 36 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030773755
    Series Statement: Advances in Neurobiology, 26
    DDC: 612.8
    Language: English
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  • 8
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Behavioral Neuroscience.
    Description / Table of Contents: Part I Preclinical Research: Neuroendocrine Mechanisms of Social Bonds and Separation Stress in Rodents, Dogs, and Other Species -- Methods and Challenges in Investigating Sex-Specific Consequences of Social Stressors in Adolescence in Rats: Is It the Stress or the Social or the Stage of Development?- Social stress-induced neuroinflammation and mitochondrial dysfunction as a link to depression and cardiovascular disease comorbidity -- Mean Girls: Social Stress Models for Female Rodents -- Development of Mixed Anxiety/ Depression-Like State as a Consequence of Chronic Anxiety: Review of Experimental Data -- Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse -- Social Stress and Aggression in Murine Models -- More or less: glucocorticoid roles in aggression -- Neurobiological Bases of Urges for Alcohol Consumption After Social Stress -- Epigenetics of Aggression -- Part II Human Research: Early Life Stress and Neurodevelopment in Adolescence: Implications for Risk and Adaptation -- Effects of Parenting Environment on Child and Adolescent Social-Emotional Brain Function -- The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans -- Social Acts and Anticipation of Social Feedback -- Clinical Outcomes of Severe Forms of Early Social Stress -- Childhood Violence Exposure, Inflammation, and Cardiometabolic Health -- Social Support Effects on Neural Stress and Alcohol Reward Responses -- Neural Underpinnings of Social Stress in Human Addiction.
    Abstract: Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
    Type of Medium: Online Resource
    Pages: VIII, 515 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031042560
    Series Statement: Current Topics in Behavioral Neurosciences, 54
    DDC: 612.8
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Animal migration. ; Biology Technique. ; Physiology. ; Behavioral Neuroscience. ; Animal Migration. ; Experimental Organisms. ; Animal Physiology.
    Description / Table of Contents: Preface -- Chapter 1. Studying Birds -- Chapter 2. Mapping Sentences and Facet Theory -- Chapter 3. How to Develop a Mapping Sentence: The Example of Avian Sleep -- Chapter 4. Complex Avian Behaviour and Cognition: A Mapping Sentence Approach -- Chapter 5 -- Studying Avian Cognition in the Wild: Avian Psychometrics -- Chapter 6. Interpreting Avian Play, Murmuration of Starlings and Oology (Classifying Birds' Eggs) -- Chapter 7. Conclusion -- Glossary -- Index.
    Abstract: This book presents the facet theoretical framework as a tool for facilitating the conception of complex animal behaviour research and the design of research procedures through employing mapping sentences. Using the facet theoretical framework, this book takes a holistic view of bird behaviour. Components of bird behavior are identified and then reassembled to facilitate an understanding of the behaviour in the context of its natural occurrence. This provides new insight on both the parts of the behaviour and how these interact as a whole. The multi-faceted approach to designing, evaluating and understanding bird behavior presented offers a template that is adaptable for investigating a wide variety of avian species and different forms of behaviour. Behavioural biologists, animal and comparative psychologists, other natural and behavioural scientists, as well as students of these disciplines will find this book to be an interesting and enlightening read.
    Type of Medium: Online Resource
    Pages: XXXVII, 203 p. 29 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030121921
    DDC: 612.8
    Language: English
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  • 10
    Keywords: Neurosciences. ; Medical genetics. ; Immunology. ; Cell death. ; Cytology. ; Stress (Physiology). ; Neuroscience. ; Medical Genetics. ; Immunology. ; Cell Death. ; Cellular Stress.
    Description / Table of Contents: Preface -- Chapter 1: microRNAs in normal brain physiology -- Chapter 2: Ischemic stroke: An imperative need for effective therapy -- Chapter 3: MicroRNAs in ischemic stroke pathophysiology: Special emphasis on early molecular events -- Chapter 4: microRNA regulation of ischemic stroke inflammatory and immune response -- Chapter 5: Regulatory role of microRNAs in ischemic cell death -- Chapter 6: The emerging role of microRNAs in post-ischemic angiogenesis and neurogenesis -- Chapter 7: MicroRNAs as potential diagnostic, prognostic and therapeutic biomarkers in ischemic stroke -- Chapter 8: Interplay between microRNAs and other cerebrovascular diseases -- Chapter 9: New insights into the regulatory role of lncRNA, circRNA, piRNAs, and ceRNAs in ischemic stroke -- Chapter 10: Computational resources for microRNA research -- Chapter 11: MicroRNA-targeted therapeutics for ischemic stroke: Status, gaps and the way forward.
    Abstract: There has been an enormous increase in information relating to microRNA (miRNA) and its strategic role in numerous diseases. This book reviews the emerging role of microRNAs in cerebral ischemia, providing comprehensive details of the links between this small RNA molecule and ischemic stroke, the more prevalent of the two main types of stroke. The chapters address questions relating to microRNA’s function in various pathological features of stroke, like oxidative stress, excitotoxicity and cell death, as well as its role as a biomarker and diagnostic agent, and the current therapeutic interventions. Further, the book highlights the latest research on how miRNAs contribute to neuroregeneration following stroke, discussing the myriad computational tools and databases used in miRNA research, and decsribes how how miRNA modulates other cerebrovascular diseases. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.
    Type of Medium: Online Resource
    Pages: XVI, 138 p. 7 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811547980
    DDC: 612.8
    Language: English
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  • 11
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nutrition   . ; Quantitative research. ; Nervous system Diseases. ; Neuroimmunology. ; Neuroscience. ; Nutrition. ; Data Analysis and Big Data. ; Neurological Disorders. ; Neuroimmunology.
    Description / Table of Contents: Chapter 1. Nutrigenomics; a broader concept -- Chapter 2. Gene-environment interaction -- Chapter 3. Gene-gut-brain - axis (gene–based personalized medicine) -- Chapter 4. Nutrigenomics of aging -- Chapter 5. Nutrigenomics and Mental health -- Chapter 6. Nutrigenomics and neurodevelopmental disorders -- Chapter 7. Nutrigenomics and Alzheimer’s disease -- Chapter 8. Nutrigenomics and Parkinson’s Disease -- Chapter 9. Nutrigenomics, nutrigenetics and big data -- Chapter 10. Nutrigenomics and Development -- Chapter 11. Early Child malnutrition and neurodevelopment -- Chapter 12. The emerging role of vit D deficiency and Parkinson’s Disease risk -- Chapter 13. Nutrigenomics and autophagy crosstalk -- Chapter 14. Nanoparticles in food additives and brain health.
    Abstract: This book highlights the effect of complex interactions between numerous genetic and environmental factors, including food intake, physical activity, age, and stress on brain physiology and function. It further discusses the mechanistic connection between nutrition and aging towards understanding the effect of the brain on longevity. The book also reviews the efficiency of nutraceutical compounds for treating and preventing of neurodevelopmental and neurodegenerative disorders. It also discusses the role of gut microbiota on the gut-brain axis and presents the role of nutrition in neurological inflammatory diseases.
    Type of Medium: Online Resource
    Pages: VII, 234 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811692055
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 12
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Medical genetics. ; Neuroscience. ; Medical Genetics.
    Description / Table of Contents: A hypothesis of circulated microRnas implication in high incidence of atrial fibrillation and other electrocardiographic abnormalities in cancer patients -- Central Line-associated Bloodstream Infections (CLABSI) Incidence and the role of obesity: a prospective, observational study in Greece -- Number of brain states in an N-body dynamical scenario according to the universal Bekenstein entropy bound -- Burden and sleeping disorders of family caregivers of Hemodialysis patients with Chronic Kidney Disease-End Stage. A cross-sectional study -- Quality of life in type 2 diabetes mellitus patients with neuropsychological deficits -- A framework for assessing the impact of information seeking behavior on cancer patients’ long-term prognosis -- Sleeping Disorders and Health Related Quality of Life in Hemodialysis patients with Chronic Renal Disease in Greece -- Subjective Quality of Life, Religiousness and Spiritual Experience in Greek Orthodox Christians: Data from Healthy Aging and Patients with Cardiovascular Disease -- Mini-Mental State Examination: Greek normative data stratified by age and education in a large sample of 925 community-dwelling healthy participants -- The role of the family in the care of Alzheimer patients -- Prevalence of Stroke Cases in Warangal, Telangana Region, India: A Hospital-Based Case Study -- Compliance of Patients with Acute Coronary Syndrome with treatment following their hospitalization from the Cardiac Coronary Unit -- Using a Virtual Reality Serious Game to Assess the Performance of Older Adults with Frailty -- Characteristics and survival rates in ward patients requiring evaluation by Intensivist in Greece.
    Abstract: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.
    Type of Medium: Online Resource
    Pages: X, 155 p. 10 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030326371
    Series Statement: Advances in Experimental Medicine and Biology, 1196
    DDC: 612.8
    Language: English
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  • 13
    Keywords: Neurosciences. ; Psychobiology. ; Human behavior. ; Pharmacology. ; Psychiatry. ; Pain medicine. ; Neuroscience. ; Behavioral Neuroscience. ; Pharmacology. ; Psychiatry. ; Pain Medicine.
    Description / Table of Contents: CLINICAL PROFILE AND TREATMENTS -- ADHD in children and adults: diagnosis and prognosis -- Treatment strategies -- Psychostimulants – treatment efficacy and problems -- Recent developments and future options for pharmacological treatments for ADHD -- GENETICS -- Genetics of ADHD (including CNVs) -- Genes , cognitive function and ADHD -- Epigenetics and ADHD -- CO-MORBIDITY -- ADHD and comorbid depression -- ADHD and autism -- Aggression and ADHD -- Obesity and ADHD (+ cytokines?) -- Sleep circadian rhythms and ADHD -- Substance misuse -- ASSESSING BRAIN FUNCTION / DYSFUNCTION -- EEG and ADHD (the skeptical view) -- Update on imaging – with connectivity -- Visual processing substrates for ADHD -- Cortical microstructure / connectivity -- ANIMAL AND IN VITRO STUDIES -- Critique of animal models -- Update on circuits for impulsive behaviour -- Zebrafish -- Update on DA transporter and ADHD -- Arousal, noradrenaline and ADHD -- FUTURE DIRECTIONS -- Stem cells for disease modelling -- Microbiome and ADHD -- Adult ADHD.
    Abstract: New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest developments in preclinical and clinical research of Attention Deficit Hyperactivity Disorder. As well as updating key chapters that were included in an earlier edition, this volume includes some new topics that are attracting a great deal of interest and point the way to new and promising directions for future research. The chapters follow five main themes: Current perspectives on the clinical profile of ADHD and its treatment, common co-occurring conditions, neurobiological studies examining brain function and genetics, animal and in vitro studies, and future directions. This combination of topics emphasises the translational relevance and validity of preclinical research so as to enable a better understanding of ADHD and to highlight the promising strategies for developing new treatments.
    Type of Medium: Online Resource
    Pages: VIII, 501 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031118029
    Series Statement: Current Topics in Behavioral Neurosciences, 57
    DDC: 612.8
    Language: English
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  • 14
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nervous system Diseases. ; Cognitive neuroscience. ; Developmental neurobiology. ; Nutrition   . ; Neuroscience. ; Neurological Disorders. ; Cognitive Neuroscience. ; Development of the Nervous System. ; Nutrition.
    Description / Table of Contents: Chapter 1. Micronutrients and Neurogenesis -- Chapter 2. Vit-E and Cognitive functions: What is the Interplay? -- Chapter 3. Microbiome and micronutrients -- Chapter 4. Iodine and Brain -- Chapter 5. Tocotrienol and Brain -- Chapter 6. Micronutrients and Depression -- Chapter 7. Micronutrients and Epilepsy -- Chapter 8. Iron Deficiency and brain cognitive functions -- Chapter 9. Micronutrients and PD -- Chapter 10. Malnutrition of Micronutrients and the brain disorders -- Chapter 11. Connections between micronutrients, cerebral monoamines and related brain disorders -- Chapter 12. Micronutrients and Autism -- Chapter 13. Edible Bird’s Nest as Brain Food -- Chapter 14. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Traumatic Brain Injury? -- Chapter 15. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Alzheimer’s Disease? -- Chapter 16. Nutrigenomics and Brain.
    Abstract: This book comprehensively reviews the relationship between micronutrients and brain in health and diseases. It explains the relationship between micronutrients and brain functions, neurogenesis, and cognitive functions. The book also explores the relationship between micronutrients and brain disorders including depression, epilepsy, PD, and Autism. It further explores the recent advancements in understanding the important role of micronutrients as therapeutics in various brain disorders like TBI and AD. Lastly, it presents an overview of micronutrients as neuroprotective agents along with the main principles of nutrigenomics.
    Type of Medium: Online Resource
    Pages: XVII, 308 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811664670
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 15
    Keywords: Neurosciences. ; Proteins. ; Nervous system Diseases. ; Genetics. ; Neuroscience. ; Proteins. ; Neurological Disorders. ; Genetics.
    Description / Table of Contents: Chapter 1. Proteins Commonly Linked to Autism Spectrum Disorder -- Chapter 2. Protein Aggregation and Recycling -- Chapter 3. Neuron Membrane and Trafficking Protein Kinases (PKA&B) involved in ASD -- Chapter 4. Proteomic profiling in children with ASD -- Chapter 5. Molecular Protein biomarkers for developing diagnostics and therapeutic interventions.Gene Regulation in Autism. OR Neurodevelopmental Epigenomics -- Chapter 6. Chromatin and Epigenetic Regulation in ASD -- Chapter 7. Autism and the Scaffolding Protein Neurobeachin -- Chapter 8. Genomic Profiling in ADHD subjects -- Chapter 9. ADHD and Epigenetics Regulation -- Chapter 10. Proteomic Approach in ADHD -- Chapter 11. DHD and the Dopamine Transporter (DAT) -- Chapter 12. Protein Kinases involved in ADHD -- Chapter 13. ADHD and Cell Adhesion Molecule 1 – CAM 1 (CADM1 gene) -- Chapter 14. ASD and Cell Adhesion Molecule Astrotactin -- Chapter 15. Possible therapeutic interventions through proteins in ADHD.
    Abstract: This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.
    Type of Medium: Online Resource
    Pages: XV, 339 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811597817
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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  • 16
    Keywords: Psychobiology. ; Human behavior. ; Developmental psychology. ; Linguistics. ; Physical anthropology. ; Behavioral Neuroscience. ; Child and Adolescence Psychology. ; Linguistics. ; Physical-Biological Anthropology.
    Description / Table of Contents: Chapter 1. Evidence for the gestural origins of language that is not incompatible with the vocal theory of language origins -- Chapter 2. Primate Voice Physiology: Similarities and Difference between Humans and Non-Human Primates -- Chapter 3. Integrations of multiple abilities underlying the evolution of primate vocalizations -- Chapter 4. Conversational rules among primate species -- Chapter 5. Language evolution from a perspective of Broca’s area -- Chapter 6. Social scaffolding of the development of vocal communication and language during infancy -- Chapter 7. Emergence of the distinction between "verbal" and "musical" skills in early childhood development -- Chapter 8. Yakut tradition of "Talking Jew's Harp" and its relation to vowel harmony as a paradigm of formative influence of music on language -- Chapter 9. Were musicians and artists in the Ice Age caves likely with autism spectrum disorder? - A neurodiversity hypothesis to explain the co-emergence of art and music as a type of prosodic protolanguage.
    Abstract: This book summarizes the latest research on the origins of language, with a focus on the process of evolution and differentiation of language. It provides an update on the earlier successful book, “The Origins of Language” edited by Nobuo Masataka and published in 2008, with new content on emerging topics. Drawing on the empirical evidence in each respective chapter, the editor presents a coherent account of how language evolved, how music differentiated from language, and how humans finally became neurodivergent as a species. Chapters on nonhuman primate communication reveal that the evolution of language required the neural rewiring of circuits that controlled vocalization. Language contributed not only to the differentiation of our conceptual ability but also to the differentiation of psychic functions of concepts, emotion, and behavior. It is noteworthy that a rudimentary form of syntax (regularity of call sequences) has emerged in nonhuman primates. The following chapters explain how music differentiated from language, whereas the pre-linguistic system, or the “prosodic protolanguage,” in nonhuman primates provided a precursor for both language and music. Readers will gain a new understanding of music as a rudimentary form of language that has been discarded in the course of evolution and its role in restoring the primordial synthesis in the human psyche. The discussion leads to an inspiring insight into autism and neurodiversity in humans. This thought-provoking and carefully presented book will appeal to a wide range of readers in linguistics, psychology, phonology, biology, anthropology and music.
    Type of Medium: Online Resource
    Pages: IX, 345 p. 29 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811542503
    DDC: 612.8
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Evolution (Biology). ; Acoustics. ; Vertebrates. ; Coding theory. ; Information theory. ; Communication. ; Behavioral Neuroscience. ; Evolutionary Biology. ; Acoustics. ; Vertebrate Zoology. ; Coding and Information Theory. ; Media and Communication.
    Description / Table of Contents: Acoustic Coding Strategies Through the Lens of the Mathematical Theory of Communication -- To Shout or to Whisper? Strategies for Encoding Public and Private Information in Sound Signals -- The Bird Dawn Chorus Revisited -- Coding Human Languages for Long-Range Communication in Natural Ecological Environments: Shouting, Whistling, and Drumming -- Coding of Static Information in Terrestrial Mammal Vocal Signals -- Coding for ‘Dynamic’ Information: Vocal Expression of Emotional Arousal and Valence in Non-human Animals -- Seasonal Hormone Fluctuations and Song Structure of Birds -- From Vocal to Neural Encoding: A Transversal Investigation of Information Transmission at Long Distance in Birds -- Mother–Offspring Vocal Recognition and Social System in Pinnipeds -- Acoustic Coding of Information in a Complex Social Network: Identity Signaling in Northern Elephant Seals -- How Songbird Females Sample Male Song: Communication Networks and Mate Choice -- Interspecific Communication: Gaining Information from Heterospecific Alarm Calls -- A Framework to Understand Interspecific Multimodal Signaling Systems.
    Abstract: Information is a core concept in animal communication: individuals routinely produce, acquire, process and store information, which provides the basis for their social life. This book focuses on how animal acoustic signals code information and how this coding can be shaped by various environmental and social constraints. Taking birds and mammals, including humans, as models, the authors explore such topics as communication strategies for “public” and “private” signaling, static and dynamic signaling, the diversity of coded information and the way information is decoded by the receiver. The book appeals to a wide audience, ranging from bioacousticians, ethologists and ecologists to evolutionary biologists. Intended for students and researchers alike, it promotes the idea that Shannon and Weaver’s Mathematical Theory of Communication still represents a strong framework for understanding all aspects of the communication process, including its dynamic dimensions.
    Type of Medium: Online Resource
    Pages: X, 325 p. 55 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030392000
    Series Statement: Animal Signals and Communication, 7
    DDC: 612.8
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Medical genetics. ; Neuroscience. ; Medical Genetics.
    Description / Table of Contents: In Silico and In Vivo Studies on Quercetin as Potential Anti- Parkinson Agent -- Exhaled Breath Condensate (EBC). Is it a viable source of biomarkers for lung diseases? -- Treatment development for Alzheimer's disease: how are we doing? -- Microbiome hijacking towards an integrative pest management pipeline -- Regulation and roles of autophagy in the brain -- Three-dimensional models for studying neurodegenerative and neurodevelopmental diseases -- Assessment of factors contributing to the enhancement of memory and cognitive abilities in the context of neurosciences -- Buccal Mucosa Biomarkers in Alzheimer’s Disease -- Engaging social interest and creating awareness for the behavioural and psychological symptoms of dementia -- Structural study of the DNA – Clock/Bmal1 complex provides insights for the role of cortisol, hGR and HPA axis in stress management and sleep disorders -- The Effects of Quantum Entanglement on Chromatin and Gene Expression -- Olive Oil Polyphenols in Neurodegenerative Pathologies -- Human pluripotent stem cells as in vitro models of neurodegenerative diseases -- Nutritional Lipidomics in Alzheimer's Disease -- Alzeheimer’s Disease Therapeutic Approaches -- Stress and Wellbeing of Psychiatry Trainees: A Literature Review -- Brief Cognitive Tests in the case of Dementia and Alzheimer’s Disease Early Diagnosis -- Synthesis, Molecular Docking studies and Biological Evaluation of N-Acylarylhydrazones as Anti-inflammatory agents -- Exosome biomarkers revolutionize preclinical diagnosis of neurodegenerative diseases and assessment of treatment responses in clinical trials -- Biomarkers as a different approach in prevention and treatment of drug addiction (preliminary study) -- Sleep disorders and Restless Leg Syndrome in hemodialysis patients in Greece: a cross-sectional study -- Craniofacial and neurological phenotype in a patient with de novo 18q microdeletion and 18p microduplication -- What do recent clinical trials teach us about the etiology of AD -- Developmental Biology and Transgenic Avian Embryology: Body Alterity Bioart Wet Lab -- Gene editing, sexual reproduction and the arts: the present, the future and the imagined -- Amyotrophic Lateral Sclerosis: Current status in diagnostic biomarkers -- Synthesis and Characterization of Biologically Significant, 5-[N,N-dialkylamino alkoxy] azaindole 2-one,3- thiosemicarbazones and 5-[N,N-dialkylamino alkoxy] azaindole 3-hydrazone, 2-ones -- Genetic counseling for adult-onset spinal and bulbar muscular atrophy (Kennedy syndrome). Multiple cases of prenatal testing in a family -- Transcriptomics and Metabolomics in Amyotrophic Lateral Sclerosis -- Ocimum Sanctum Linn: A Potential Adjunct Therapy for Hyperhomocysteinemia – Induced Vascular Dementia -- Alzheimer's disease: The role of mutations in protein folding.
    Abstract: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people. .
    Type of Medium: Online Resource
    Pages: XII, 262 p. 42 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030326333
    Series Statement: Advances in Experimental Medicine and Biology, 1195
    DDC: 612.8
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Neuropsychology. ; Neural circuitry. ; Nervous system Diseases. ; Neuroscience. ; Neuropsychology. ; Neural Circuits. ; Neurological Disorders.
    Description / Table of Contents: PART I. Molecular Gears of the Circadian Clock -- Introduction to the Clock System -- Circadian Clocks, Sleep, and Metabolism -- Linking Depression to Epigenetics: Role of the Circadian Clock -- PART II. Brain Regions Implicated in Circadian Rhythms -- The Brain's Reward System in Health and Disease -- Brain Clocks, Sleep and Mood -- Astrocyte Circadian Timekeeping in Brain Health and Neurodegeneration -- PART III. Clock and Mental Illness -- The Role of the Circadian System in Attention Deficit Hyperactivity Disorder -- How Psychoactive Drugs and the Circadian Clock Are Enlightening One Another -- Circadian Rhythms in Mood Disorders -- The Reciprocal Interaction Between Sleep and Alzheimer’s Disease.
    Abstract: In this book, leading experts in the field review how circadian rhythms impact the brain. An essential function of mammalian life is the exploitation of the regularities provided by the 24-hour cycle of day and night. The development and evolution of circadian clock mechanisms have allowed us to optimally adapt our behavior and physiology to the external world. Not surprisingly, a growing body of evidence links the disruption of circadian rhythms by genetic, lifestyle and environmental factors to illnesses of the brain. In the first section of the book, readers will learn about the molecular and anatomic architecture of circadian function in mammals. The ways in which environmental disruptions and misalignments can influence such mechanisms and therefore impair brain function and health status are also addressed. In the second part, the focus shifts to those brain regions responsible for brain function and the body-wide regulation of circadian function. Amongst others, special attention is paid to the role of astrocytes and the brain’s reward and hyprocretin / orexin systems. The book concludes with an extensive discussion on the consequences of circadian rhythm dysfunction. Several chapters present the latest findings on Attention Deficit Hyperactivity Disorder, schizophrenia, autism spectrum disorder, drug abuse and mood disorders. Written by auhorities in the field, the book provides a state-of-the-art review of the latest findings on circadian clocks in the brain and highlights their potentially far-reaching impacts on our health and well-being. As such, it is essential reading for all neuroscientists and clinicians seeking to understand the intricate connections between circadian rhythms and brain health and illness.
    Type of Medium: Online Resource
    Pages: XI, 188 p. 15 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030811471
    Series Statement: Advances in Experimental Medicine and Biology, 1344
    DDC: 612.8
    Language: English
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  • 20
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Medical genetics. ; Bioinformatics. ; Neuroscience. ; Medical Genetics. ; Bioinformatics. ; Computational and Systems Biology.
    Description / Table of Contents: 1-Attitudes and smoking prevalence among undergraduate students in central Greece -- 2-Care of patients with Alzheimer’s disease -- 3-Regulation of antioxidant enzymes levels in rat brain -- 4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy -- 5-Cerebral critical closing pressure at concomitant traumatic brain injury -- 6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias -- 7-The Development of Antisense RNA Treatments using Engineered Protein Substrates -- 8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases -- 9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma -- 10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study -- 11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients -- 12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial -- 13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents -- 14-Stress system activation analysis in Greek female adolescents: a bioimpedance study -- 15-Kisspeptin and the genetic obesity interactome -- 16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis -- 17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia -- 18-Ebola virus disease and current therapeutic strategies; A review -- 19-Hyperbaric Oxygen Therapy effect on “Kinesia Paradoxa” Brain Circuits -- 20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line -- 21-Phospholipid Fatty Acid Profile of Spirulina platensis -- 22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study -- 23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives -- 24-Force spectroscopy in mechanical protein domains unfolding -- 25-Investigating the genetic component of Parkinson’s Disease -- 26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition -- 27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases -- 28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students -- 29-Synthesis, in silico stuiesand biological evaluation of 1, 3 ,4 oxadiazino indole derivatives -- 30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies -- 31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy -- 32-Microbes and the games they play -- 33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy -- 34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study -- 35-The effect of nutrients on Alzheimer’s disease biomarkers: A metabolomic approach -- 36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease -- 37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases -- 38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1 -- 39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome -- 40-Clinical and molecular study of common thrombophilia mutation prothrombin G20210A -- 41-Prenatal genetic testing for X-linked hypohidrotic ectodermal dysplasia -- 42-Preimplantation genetic testing for spastic paraplegia type 3 -- 43-Synthesis, anti-inflammatory activity and in-silico studies of some new 3-({P-DIMETHYLAMINO}BENZYLIDENE YDRAZINYLIDENE)-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES -- 44-Design, characterization and docking studies of some novel isatin derivatives for anticonvulsant and antidepressant activity -- 45-Skin mirrors Brain: A Chance for Alzheimer’s Disease Research -- 46-Mitochondrial homeostasis in neurodegeneration and ageing -- 47-The Alzheimer's Disease Chronicles: will evidence triumph over adversity? -- 48-Liposomes: Production Methods and Application in Alzheimer’s Disease -- 49-Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision -- 50-Biomarkers and Precision Medicine in Alzheimer’s Disease -- 51-The role of microRNAs in thrombosis -- 52-Photo-oxygenation: an innovative new therapeutic approach against amyloidoses.
    Abstract: The 4th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The relation between genetics and its effect on several diseases are thoroughly examined in this volume. This volume focuses on the sessions from the conference on Genetics and Neurodegenerative Diseases.
    Type of Medium: Online Resource
    Pages: XV, 435 p. 133 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030787875
    Series Statement: Advances in Experimental Medicine and Biology, 1339
    DDC: 612.8
    Language: English
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  • 21
    Keywords: Neurosciences. ; Nervous system Diseases. ; Developmental neurobiology. ; Neuroimmunology. ; Neuroscience. ; Neurological Disorders. ; Development of the Nervous System. ; Neuroimmunology.
    Description / Table of Contents: Chapter 1_Glial Biology: A Historical Perspective -- Chapter 2_. Basic Biology of Astrocytes -- Chapter 3_ Oligodendrocyte: Structure, Function and Pathology -- Chapter 4_ Oligodendroglial-astroglial cell-cell communication in the Central Nervous System -- Chapter 5_ Oligodendroglial Gap junction communication in CNS myelination and demyelination -- Chapter 6_ Generation and maturation of macroglia in central nervous system. – Chapter 7_ Origin and Development of Microglia -- Chapter 8_ Biology of Astrocytes in CNS Infection -- Chapter 9_ Role of reactive astrocytes in Alzheimer’s disease -- Chapter 10_ Role of astrocyte dysfunction in Parkinson’s Disease pathogenesis -- Chapter 11_ Astroglial Pathology in Major Depressive Disorders: Metabolic and Molecular Aspects -- Chapter 12_ Glia in epilepsy: an overview -- Chapter 13_ Tumors of the Glia: Recent Advances -- Chapter 14_ Astroglial iron homeostasis and neurodegenerative diseases -- Chapter 15_ Glial cells are Key Orchestrators of Neural degeneration in Basal Ganglia Disorders: Classical and Contemporary observations -- Chapter 16_ Interplay between microglia and astrocytes during neuroinflammation: Lessons learnt from in-vitro and in-vivo models of sporadic Amyotrophic Lateral Sclerosis -- Chapter 17_ Microglia orchestrate inflammation via HSP60 driven signaling pathway: a road map of molecular mechanism -- Chapter 18_ Biphasic Role of Microglia in Brain Health and Disease -- Chapter 19_ Multidimensional roles of Microglial Cells in Neuroviral Infections -- Chapter 20_ Microglia Aging -- Chapter 21_ Emerging Role of Satellite and Schwann Cells of Peripheral Neuroglial System in Nerve Repair -- Chapter 22_ Insights in the role of glia in mediating brain plasticity in health and disease -- Chapter 23_ The glial perspective of energy homeostasis, neuroinflammation and neuro-nutraceuticals -- Chapter 24_ Role of glia in Huntington’s disease -- Chapter 25_ Endogenous mediators of neuroinflammation: The endocannabinoid system at the retina -- Chapter 26_ Drosophila melanogaster: An Immaculate Model for Glial Research -- Chapter 27_In-vitro models of Astrocytes: An Overview.
    Abstract: This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and diseases. It discusses the latest advances in understanding their origin, differentiation, and hemostasis. The book also examines the role of microglial cells in central nervous system (CNS) development, maintenance, and synaptic plasticity. Further, the book presents the functions of astrocytes in healthy CNS and their critical role in CNS disorders, including Parkinson's and Alzheimer's diseases. Notably, the book describes the pathobiology, molecular pathogenesis, stem cells, and imaging characteristics of gliomas. It defines the role of glial cells in regulating iron homeostasis and their effect on the neurodegeneration of neurons. Lastly, it covers the structure, function, and pathology of oligodendrocytes and their role in neuronal health and disease.
    Type of Medium: Online Resource
    Pages: XXXIV, 745 p. 82 illus., 75 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811683138
    DDC: 612.8
    Language: English
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  • 22
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Medical genetics. ; Bioinformatics. ; Neuroscience. ; Medical Genetics. ; Bioinformatics. ; Computational and Systems Biology.
    Description / Table of Contents: 1-Attitudes and smoking prevalence among undergraduate students in central Greece -- 2-Care of patients with Alzheimer’s disease -- 3-Regulation of antioxidant enzymes levels in rat brain -- 4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy -- 5-Cerebral critical closing pressure at concomitant traumatic brain injury -- 6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias -- 7-The Development of Antisense RNA Treatments using Engineered Protein Substrates -- 8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases -- 9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma -- 10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study -- 11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients -- 12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial -- 13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents -- 14-Stress system activation analysis in Greek female adolescents: a bioimpedance study -- 15-Kisspeptin and the genetic obesity interactome -- 16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis -- 17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia -- 18-Ebola virus disease and current therapeutic strategies; A review -- 19-Hyperbaric Oxygen Therapy effect on “Kinesia Paradoxa” Brain Circuits -- 20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line -- 21-Phospholipid Fatty Acid Profile of Spirulina platensis -- 22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study -- 23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives -- 24-Force spectroscopy in mechanical protein domains unfolding -- 25-Investigating the genetic component of Parkinson’s Disease -- 26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition -- 27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases -- 28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students -- 29-Synthesis, in silico stuiesand biological evaluation of 1, 3 ,4 oxadiazino indole derivatives -- 30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies -- 31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy -- 32-Microbes and the games they play -- 33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy -- 34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study -- 35-The effect of nutrients on Alzheimer’s disease biomarkers: A metabolomic approach -- 36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease -- 37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases -- 38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1 -- 39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome -- 40-Clinical and molecular study of common thrombophilia mutation prothrombin G20210A -- 41-Prenatal genetic testing for X-linked hypohidrotic ectodermal dysplasia -- 42-Preimplantation genetic testing for spastic paraplegia type 3 -- 43-Synthesis, anti-inflammatory activity and in-silico studies of some new 3-({P-DIMETHYLAMINO}BENZYLIDENE YDRAZINYLIDENE)-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES -- 44-Design, characterization and docking studies of some novel isatin derivatives for anticonvulsant and antidepressant activity -- 45-Skin mirrors Brain: A Chance for Alzheimer’s Disease Research -- 46-Mitochondrial homeostasis in neurodegeneration and ageing -- 47-The Alzheimer's Disease Chronicles: will evidence triumph over adversity? -- 48-Liposomes: Production Methods and Application in Alzheimer’s Disease -- 49-Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision -- 50-Biomarkers and Precision Medicine in Alzheimer’s Disease -- 51-The role of microRNAs in thrombosis -- 52-Photo-oxygenation: an innovative new therapeutic approach against amyloidoses.
    Abstract: The 5th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2022) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. This volume focuses on the sessions from the conference on Neuroscientific Advances.
    Type of Medium: Online Resource
    Pages: XXXI, 673 p. 58 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031319860
    Series Statement: Advances in Experimental Medicine and Biology, 1425
    DDC: 612.8
    Language: English
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  • 23
    Keywords: Neurosciences. ; Developmental biology. ; Nervous system Diseases. ; Neuroscience. ; Developmental Biology and Stem Cells. ; Neurological Disorders.
    Description / Table of Contents: Chapter 1. History, origin and types of neurological disorders -- Chapter 2. Mechanistic approach involved in the progression of Neurodegenerative disorders -- Chapter 3. Isolation, characterization and differentiation of stem cells -- Chapter 4. Role of Stem cells as a protective agent against neurological complications -- Chapter 5. Mesenchymal stem cells and their application against neurodegenerative disorders -- Chapter 6. iPSCs and their role in amelioration of neurodegenerative disorders -- Chapter 7. Isolation, characterization and detailed history of exosomes derived from stem cells and their epigenetic biology -- Chapter 8. Stem cells vs exosomes: promising therapeutic approach and biomarkers agent against neurodegenerative disorders -- Chapter 9. Role of stem cells and derived exosomes as a novel therapeutic agent against neuroinflammation and stroke -- Chapter 10. Role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer’s and Parkinson's disease -- Chapter 11. Role of stem cells and derived exosomes and associated signalling molecules involved in neuroprotection -- Chapter 12. Exosome as nanoparticles against neurodegenerative disorders.
    Abstract: This book explores the therapeutic approaches of stem cells and stem cell-derived exosomes against neurodegenerative disorders (NDDs). The initial chapters introduce different neurodegenerative diseases and discuss the mechanistic aspects of their progression. The subsequent chapters cover strategies for the isolation, characterization, and differentiation of stem cells. In turn, the book reviews the protective role of stem cells against neurological disorders and examines regenerative approaches to treat neurological diseases using mesenchymal stem cells. The book also presents induced pluripotent stem cell (iPSC) technology for cellular therapy, drug screening, and in-vitro modeling of neurodegenerative diseases. Lastly, the book discusses the role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer's and Parkinson's disease and in associated signaling molecules involved in neuroprotection. This book is an invaluable source for researchers working towards understanding the potential of stem cell therapy in neurodegenerative disorders.
    Type of Medium: Online Resource
    Pages: XIII, 327 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819938483
    DDC: 612.8
    Language: English
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  • 24
    Keywords: Psychobiology. ; Human behavior. ; Cognitive neuroscience. ; Psychiatry. ; Behavioral Neuroscience. ; Cognitive Neuroscience. ; Psychiatry.
    Description / Table of Contents: Discovery science chapters -- Effects of AEDs on behaviour -- How to separate effects of seizures when studying behaviour -- Depression-like behaviour in epilepsy models -- Are behavioural deficits core components of epilepsy? -- Does stress trigger seizures: evidence from animal models? -- Early life stress and epilepsy -- disease models and epilepsy -- Disease modification in epilepsy: behavioural accompaniments -- Clinical chapters -- Do psychotropic drugs cause epileptic seizures? A review of the available evidence. Peri-ictal and para-ictal psychiatric phenomena: a relatively common yet unrecognized disorder -- Can we anticipate and prevent the occurrence of iatrogenic psychiatric events caused by antiepileptic drugs and epilepsy surgery? -- Are psychiatric disorders a risk for the development of treatment-resistant epilepsy? Temporal lobectomy: does it worsen or improve presurgical psychiatric disorders? -- Suicidality in epilepsy: does it share common pathogenic mechanisms with epilepsy? -- Psychotic disorders in epilepsy: do they differ from primary psychosis? -- Do neurobiologic aspects of primary psychiatric disorders account for the relatively high prevalence of psychiatric comorbidities in epilepsy? -- Are psychogenic non-epileptic seizures really the expression of a psychogenic process?
    Abstract: Many people living with epilepsy also suffer from debilitating psychiatric and cognitive disorders. While these comorbidities have been recognized for centuries, their causation, and relationship to the epilepsy remains clouded in mystery. This volume highlights recent knowledge and findings as well as controversies in our current understanding of behavioral and psychiatric comorbidities of epilepsy.
    Type of Medium: Online Resource
    Pages: X, 351 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031032356
    Series Statement: Current Topics in Behavioral Neurosciences, 55
    DDC: 612.8
    Language: English
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  • 25
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Sex. ; Behavioral Neuroscience. ; Gender Studies.
    Description / Table of Contents: 1-Measuring Sex Differences and Similarities -- 2-Prenatal Steroid Hormones and Sex Differences in Juvenile Rhesus Macaque Behavior -- 3-Biological Approaches to Studying Gender Development -- 4-Social Influences on Gender Development: Theory and Context -- 5-Contemporary Cognitive Approaches to Gender Development: New Schemas, New Directions, and New Conceptualizations of Gender -- 6-Origins and Consequences of Childhood Gender Segregation: Towards an Integrative Developmental Systems Model -- 7-Gender, Toys, and Play: How Gendered Early Experiences Shape Later Development -- 8-Family Gender Socialization in Childhood and Adolescence -- 9-Gender Stereotypes and Education -- 10-Gender-Based Discrimination in Childhood and Adolescence -- 11-Gender and Sexuality in Disorders/Differences of Sex Development -- 12-Sexuality Development in Childhood -- 13-Sexual Pleasure in Adolescence: A Developmental Sexual Embodiment Perspective -- 14-Pornography Use in Adolescence and Young Adulthood -- 15-A Review of Theoretical Models and Lifespan Approaches to the Study of Sexual Offending -- 16-Learned but Not Chosen: A Reward Competition Feedback Model for the Origins of Sexual Preferences and Orientations -- 17-Carving the Biodevelopment of Same-Sex Sexual Orientation at Its Joints -- 18-Mental Health Among LGBT Youth -- 19-Asexuality: When Sexual Attraction is Lacking -- 20-Erotic Target Identity Inversions -- 21-Consensual Non-monogamy from a Developmental Perspective.
    Abstract: This book showcases a wealth of knowledge and insight on gender and sexuality development. With contributions from leading researchers, it covers a comprehensive set of topics at the forefront of the field and strikes a balance between traditional and emerging areas of study. Given that gender and sexuality are shaped by myriad influences, this book is modelled on an interdisciplinary perspective and delves into biological, comparative, psychological, cognitive, social, cultural, and clinical approaches. In so doing, this collection conveys the rich tapestry of gender and sexuality science and will hold value for many. For those already in the field, this book provides an excellent resource for brushing up on the latest and for inspiring the next phases of scientific investigation. Those who are newer to the field, including undergraduate and graduate students, stand to gain tremendously from not only the thoughtful and informative content, but also from the interdisciplinary approach modelled throughout the book. Beyond academia, this book is a valuable resource for clinicians and policy makers who deal with child and adolescent issues.
    Type of Medium: Online Resource
    Pages: XXIII, 636 p. 21 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030842734
    Series Statement: Focus on Sexuality Research,
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Psychobiology. ; Human behavior. ; Physical anthropology. ; Cognitive psychology. ; Animal welfare Moral and ethical aspects. ; Animal migration. ; Animal culture. ; Behavioral Neuroscience. ; Physical-Biological Anthropology. ; Cognitive Psychology. ; Animal Ethics. ; Animal Migration. ; Animal Science.
    Description / Table of Contents: Part I: Introduction -- Chapter 1: Recent developments in primatology and their relevance to the study of Tibetan macaques -- Part II: Social Behavior and Dynamics in Tibetan Macaques -- Chapter 2: Social and Life History Strategies of Tibetan Macaques at Mt. Huangshan -- Chapter 3: Size Matters in Primate Societies: How Social Mobility Relates to Social Stability in Tibetan and Japanese Macaques -- Chapter 4: Behavioral exchange and interchange as strategies to facilitate social relationships in Tibetan macaques -- Chapter 5: Social relationships impact collective decision-making in Tibetan macaques -- Chapter 6: Considering Social Play in Primates: A Case Study in Juvenile Tibetan Macaques (Macacathibetana) -- Chapter 7: The Vocal Repertoire of Tibetan Macaques (Macacathibetana) and Congeneric Comparisons -- Chapter 8: Tibetan Macaque Social Style: Co-variant and Quasi-independent Evolution -- Part III: Evolution of Rituals: Insights from Bridging Behavior -- Chapter 9: Preliminary observations of female-female bridging behavior in Tibetan macaques (Macacathibetana) at Mt. Huangshan, China -- Chapter 10: Bridging Behavior and Male-Infant Interactions in Macacathibetana and M. assamensis: Insight into the Evolution of Social Behavior in the sinica Species-group of Macaques -- Part IV: Livingwith Microbes, Parasites, and Diseases -- Chapter 11: The gut microbiome of Tibetan macaques: composition, influencing factors and function in feeding ecology -- Chapter 12: Medicinal Properties in the Diet of Tibetan Macaques at Mt. Huangshan - A Case for Self-medication -- Chapter 13: Primate infectious disease ecology: Insights and future directions at the human-macaque interface -- Part V: Emerging Technologies in Primatology -- Chapter 14: High field MRI technology for behavioral and cognitive studies in macaques in vivo.
    Abstract: This open access book summarizes the multi-disciplinary results of one of China’s main primatological research projects on the endemic Tibetan macaque (Macaca thibetana), which had continued for over 30 years, but which had never been reported on systematically. Dedicated to this exceptional Old World monkey, this book makes the work of Chinese primatologists on the social behavior, cooperation, culture, cognition, group dynamics, and emerging technologies in primate research accessible to the international scientific community. One of the most impressive Asian monkeys, and the largest member of its genus, the Tibetan macaque deserves to be better known. This volume goes a long way towards bringing this species into the spotlight with many excellent behavioral analyses from the field.- Frans de Waal, Professor of Psychology, Emory University, USA. Macaques matter. To understand primate patterns and trends, and to gain important insight into humanity, we need to augment and expand our engagement with the most successful and widespread primate genus aside from Homo. This volume focuses on the Tibetan macaque, a fascinating species with much to tell us about social behavior, physiology, complexity and the macaque knack for interfacing with humans. This book is doubly important for primatology in that beyond containing core information on this macaque species, it also reflects an effective integrated collaboration between Chinese scholars and a range of international colleagues—exactly the type of collaborative engagement primatology needs. This volume is a critical contribution to a global primatology. - Agustín Fuentes, Professor of Anthropology, University of Notre Dame, USA. I have many fond memories of my association with Mt. Huangshan research beginning in 1983, when together with Professor Qishan Wang we established this site. It is such a beautiful place and I miss it. It is gratifying to see how far research has progressed since we began work there, becoming more internationalized and very much a collaborative endeavor under the long-term direction of Professor Jin-Hua Li and colleagues. This book highlights the increased interest in this species, representing a variety of disciplines ranging from macro aspects of behavior, cognition and sociality, to micro aspects of microbes, parasites and disease, authored by a group of renowned Chinese and international primatologists. I applaud their efforts and expect more interesting work to come from this site in the years ahead.- Kazuo Wada, Professor Emeritus, Kyoto University, Japan.
    Type of Medium: Online Resource
    Pages: XVI, 302 p. 93 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030279202
    Series Statement: Fascinating Life Sciences,
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nervous system Diseases. ; Developmental neurobiology. ; Cognitive neuroscience. ; Neuroscience. ; Neurological Disorders. ; Development of the Nervous System. ; Cognitive Neuroscience.
    Description / Table of Contents: PART I. Iron, Brain Function and Behavior -- Chapter 1. Iron and Neuro-cognition -- Chapter 2. The Interplay Between Iron and Oxidative Stress in Brain Neurodegenerative Diseases -- Chapter 3. Specific Nutritional Therapeutic Approaches Targeting Iron Overload and Other Hallmarks of Brain Degenerative Diseases -- Chapter 4. Mediterranean Diet and Neuro-Cognition: Focus on Alzheimer disease -- PART II Brain disorders related to Iron -- Chapter 5. The Critical Roleplay of Iron Neurochemistry in Progression of Parkinson’s Disease -- Chapter 6. Iron-Calcium Crosstalk in Neurodegenerative Diseases -- Chapter 7. Iron and Alzheimer’s Disease -- Chapter 8. Iron and Multiple Sclerosis -- Chapter 9. Iron and Epilepsy -- Chapter 10. Iron and Subarachnoid Hemorrhage -- Chapter 11. Iron deficiency and psychiatric disorders -- Chapter 12. Iron and Neuro-developmental Disorders -- Chapter 13. Iron and Neuropathies.
    Abstract: This book explores the molecular mechanisms of iron hemostasis in the brain and discusses the cognitive and behavioral implications of iron deficiency. It presents the effect of iron dysregulation on neurophysiological mechanisms. The book provides an overview of iron metabolism and homeostasis at the cellular level and its regulation at the mRNA translation level. It emphasizes the importance of iron for brain development in fetal and early life in preterm infants. Further, it presents iron metabolism as a therapeutic target for novel pharmacological treatment against neurodevelopmental diseases and neurodegenerative disorders. It discusses the role of iron deficiency in sleep disorders and offers diagnosis and treatment of iron-related CNS diseases. Finally, it relates dysregulated expression of iron-related genes in brain tumors.
    Type of Medium: Online Resource
    Pages: XX, 280 p. 10 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811973277
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Neurosciences. ; Psychiatry. ; Psychobiology. ; Human behavior. ; Psychology, Experimental. ; Neuroscience. ; Psychiatry. ; Behavioral Neuroscience. ; Biological Psychology. ; Experimental Psychology.
    Description / Table of Contents: Overview chapter -- Imaging studies linking dopaminergic systems to impulsivity in humans -- The Genetics of Externalizing Problems -- The neuropharmacology of impulsive behaviour: ten years later -- Inhibitory control and impulsivity in childhood onset disruptive behavior disorders -- Steep discounting of future rewards as an impulsivity phenotype: a concise review -- Developmental considerations in impulsivity: Implications for research and treatment -- Reinforcer Pathology: Implications for Substance Abuse Intervention -- Impulsivity and Suicidal Behavior -- Sex differences in neural circuits underlying inhibitory control -- The role of impulsivity facets on the incidence and development of alcohol use disorders -- The neurobiology of reinforcement learning mechanisms in impulsivity.
    Abstract: This volume provides an empirical and conceptual overview of advances in our understanding of impulsivity and impulsive behaviors. Prominent scientists review the range of behavioral phenomena referred to as ‘impulsive’, as well as the defining features and psychological, neurocognitive and behavioral processes that underlie of the manifestation of impulsive behaviors, focussing on progress made and the questions remaining to be answered.
    Type of Medium: Online Resource
    Pages: VIII, 221 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030605117
    Series Statement: Current Topics in Behavioral Neurosciences, 47
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Nutrition   . ; Microbial populations. ; Nervous system Diseases. ; Neuroscience. ; Nutrition. ; Microbial Communities. ; Neurological Disorders.
    Description / Table of Contents: Gut Microbiome Brain Axis: An Introduction -- Cross talk between gut microbiota and host immune cells -- Microbiota-Gut-Brain Axis and Neurodegenerative Disorder -- Gut Microbiota Regulation of Cerebral Stroke -- Aging: Impact of Gut Microbiota -- Gut Microbiome Regulation of Appetite and Neurological Disorders -- Human diets, Gut microbiome and Neuroinflammation -- Dietary Fatty acids, Gut microbiome and Gut-Brain communication: A Current perspective -- Role of Short Chain Fatty Acids from Gut Microbiota in Neuroendocrine Pathogenesis Management -- Potential role of probiotics on gut microbiota in neurological disease -- Reversal of metabolic disorder through the restoration of gut microbiota -- Gut Microbiome and Diet: Promising Approach for Treatment of Cognitive Impairment -- Nanoplastics, Gut microbiota and Neurodegeneration -- Gut Microbiome, COVID-19, and Neurological Impairment -- Tools to study Gut Microbiome -- Germ-Free Mice Technology: opportunity for Future Research -- Gut Microbiome and Neurodegeneration: A Bioinformatics Approach.
    Abstract: This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.
    Type of Medium: Online Resource
    Pages: IX, 311 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811945304
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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    Keywords: Neurosciences. ; Nutrition   . ; Nervous system Diseases. ; Neuroscience. ; Nutrition. ; Neurological Disorders.
    Description / Table of Contents: Part 1: Neurological disorders from Background to interplay of Genetic, Epigenetic and Environmental risk factors -- Chapter 1: Phytonutrients in Neurological Disorders -- Chapter 2: Psychobiotics in health, longevity and neurological disorders -- Chapter 3: Nutritional, dietary, and lifestyle approaches for prevention and management of Alzheimer’s disease.-Chapter 4: Qualitative and Analytical Treatment of Nonlinear Dynamical systems in Neurological Diseases -- Chapter 5: Impact of a psychological follow-up of diabetics in the management of diabetes in Morocco -- Chapter 6: Neuroprotective and anxiolytic effects of date seeds phenolic compounds in Nicotinamide-Streptozotocin-Induced type 2 diabetic rats -- Chapter 7: Role of nutrition in pathogenesis of neurological disorders -- Part 2: Specific Food and Nutritional Qualities on Neruological Disorders -- Chapter 8: Best foods for repair of brain damage -- Chapter 9: Role of micronutrients in neurological development -- Chapter 10: Algae as a potential vegetative source of PUFA for the prevention of neurological disorders -- Chapter 11: Natural foods for suppressing Dementia -- Chapter 12: Nutrients' role in the treatment of Parkinson's and Alzheimer's diseases -- Chapter 13: Novel marine derived natural products for the treatment of depressive disorder -- Chapter 14: Nanoceuticals as Theranostics against Neurodegenerative diseases -- Chapter 15: Role of Antioxidant Nutraceuticals in Neurodegenerative diseases -- Part 3: Herbal remedies for Neurological disorders -- Chapter 16: Herbal drugs: Its molecular mechanism to prevent Alzheimer’s disease with special reference to non-phenolic secondary metabolites -- Chapter 17: Preventive Role And Mechanism Of Herbal Medicine In Alzheimer’s Disease With Special Reference To Phenolic Compounds -- Chapter 18: Herbal Remedies for Autism -- Chapter 19: Action of herbal products in suppressing Parkinson’s Disorder -- Chapter 20: Impact of diet on neurotransmitters.
    Abstract: This book provides the latest research on the role of nutrients in the prevention and treatment of neurological disorders. It discusses dietary supplements and dietary restrictions for combating neurological disorders, including Alzheimer’s disease, Parkinson’s disease, stroke, and epilepsy. The book also explains the impact of different nutrients such as herbal products, algae, micronutrients in stimulating the brain and central nervous system during abnormal functions. It covers the effect of the nutrients on the function of neurotransmitters, their stimulatory effect in autism, dementia, Alzheimer’s, and other neuropathological states. The book also defines the mechanistic effects of neuroprotective and psycho protective effects of natural food in repairing brain damage. This book is essential reading for neuroscientists and neurologists, and healthcare professionals.
    Type of Medium: Online Resource
    Pages: XVIII, 383 p. 45 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811681585
    Series Statement: Nutritional Neurosciences,
    DDC: 612.8
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Life sciences. ; Biophysics. ; Medical genetics. ; Neural networks (Computer science) . ; Neuroscience. ; Life Sciences. ; Biophysics. ; Medical Genetics. ; Mathematical Models of Cognitive Processes and Neural Networks.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Noise and Randomness in Science and Engineering -- Chapter 3. Various Types of Noise and their Sources -- Chapter 4. Constructive Role of Noise and Nonlinear Dynamics -- Chapter 5. Noise and Synchronization of Oscillatory Networks -- Chapter 6. Stochastic Fluctuations at Cellular and Molecular level -- Chapter 7. Various Types of Noise and their Sources in Living Organisms -- Chapter 8. Ion Channel Noise in Biological Systems -- Chapter 9. Noise in Cellular Communication -- Chapter 10. The Role of Noise in Brain Function -- Chapter 11. Noise and Gene Oscillators -- Chapter 12. Developmental Noise and Stability -- Chapter 13. Noise and Coherence in Meditation -- Chapter 14. Chaos, Stochasticity and Noise -- Chapter 15. Chance, Determinism and Laws of Nature.
    Abstract: This book illustrates the role of randomness and noise in living organisms. Traditionally, the randomness and noise have been used in understanding signal processing in communications. This book is divided into two sections, the first of which introduces readers to the various types and sources of noise and the constructive role of noise in non-linear dynamics. It also analyses the importance of randomness and noise in a variety of science and engineering applications. In turn, the second section discusses in detail the functional role of noise in biological processes for example, in case of brain function at the level of ion channel, synaptic level and even at cognitive level. These are described in various chapters. One of the challenging issue finding the neuronal correlates of various meditative states is to understand how brain controls various types of noise so as to reach a state of synchronized oscillatory state of the brain corresponding to the state of Samadhi. This is described in details in one chapter called Noise, Coherence and meditation. The concept of noise and the role of randomness in living organism raise lot of controversy for last few decades. This is discussed in a separate chapter. Finally, the epistemic and ontic nature of randomness as discussed in physical science are investigated in the context of living organism.
    Type of Medium: Online Resource
    Pages: XVII, 160 p. 16 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811695834
    DDC: 612.8
    Language: English
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    Keywords: Neurosciences. ; Neurology . ; Nervous system Diseases. ; Cognitive neuroscience. ; Neurophysiology. ; Learning Physiological aspects. ; Memory Physiological aspects. ; Neuroscience. ; Neurology. ; Neurological Disorders. ; Cognitive Neuroscience. ; Neurophysiology. ; Learning and Memory.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer’s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer’s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer’s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".
    Abstract: This book highlights the key phases and central findings of Alzheimer’s Disease research since the introduction of the label ‘Alzheimer’s Disease’ in 1910. The author, Christian Behl, puts dementia research in the context of the respective zeitgeist and summarizes the paths that have led to the currently available Alzheimer’s drugs. As the reader is taken through the major developments in Alzheimer's Disease research, particularly over the past thirty years, Behl poses critical questions: Why are the exact causes of Alzheimer's Disease still in the dark, despite all the immense, worldwide research efforts in academia as well as in the pharmaceutical industry? Why has the majority of an entire research field kept focusing on a single hypothesis that establishes the deposition of the amyloid beta peptide in the brain as the key trigger of Alzheimer's pathology, even though this concept has still not been convincingly proven in the clinics? Are there other hypotheses that might explain the pathogenesis of this complex brain disease, and if so, why were these perspectives not adequately followed? In this book, Behl tries to answer these questions. Starting with the historical background, the author illustrates the long and arduous research journey, its numerous setbacks, and the many alternative explanations for the disease, which have started gaining increasing attention and acceptance in the Alzheimer’s research community only more recently. With his deep dive into the history and progression of this research, including the most recent developments, Behl explains why he believes that it is high time to promote a paradigm shift in Alzheimer’s Disease research. The book is written for all researchers in the fields of neurobiology and neurodegeneration, as well as other biomedical fields, who would like to gain a broad and beyond the surface insight into (the key developments of) one of the most promoted research fields of our time. With its extensive literature references and over 100 illustrations, the book is also attractive for students and interested lay persons. Elaborating on all the different aspects and research approaches of this research field, the author aims to convince the reader that the underlying causes of Alzheimer’s Disease may be much more complex than previously thought and that this must be considered for future research directions. While he hopes that the Alzheimer’s research community is finally ready to shed its ‘amyloid-straitjacket’ that has hampered progress for too long, he is also convinced that a much-needed paradigm shift can guide future Alzheimer’s Disease research and provide a new and broader perspective on this age-dependent brain disease.
    Type of Medium: Online Resource
    Pages: XXV, 652 p. 116 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315701
    DDC: 612.8
    Language: English
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    Keywords: Psychobiology. ; Human behavior. ; Cognitive neuroscience. ; Psychology, Experimental. ; Behavioral Neuroscience. ; Cognitive Neuroscience. ; Experimental Psychology.
    Description / Table of Contents: The promises and pitfalls of Virtual Reality -- Setting up your VR neuroscience laboratory -- Monitoring the autonomic system in VR -- Monitoring brain activity in VR: EEG and neuroimaging -- Eye-tracking and Pupillometry in VR -- VR for Movement and Action Science -- VR for Vision Science -- VR for Emotion -- VR for Thinking and Creativity -- VR for Social Cognition -- VR as a window into Consciousness -- Aging -- Learning -- Pain -- Cognitive and motor rehabilitation -- VR for Mental Health.
    Abstract: Virtual Reality (VR) is a rapidly maturing technology that offers new and unique solutions to otherwise intractable problems in the study of cognition, behavior and neuroscience. VR removes many of the constraints imposed by laboratory paradigms, allowing us to track cognitive, behavioral and brain responses to naturalistic (or even impossible) situations without sacrificing experimental control. But VR is not a tool that can be swiftly and effortlessly integrated into existing research pipelines; currently, the benefits of VR are accompanied by a host of methodological challenges and important practical considerations. To help navigate this new methodology, this volume provides a balanced review of both the exciting new findings emerging from VR labs and the challenges and limitations that are part and parcel of VR research. This volume is an important first step toward establishing a standardised methodology for conducting research in VR. To this end, the volume provides a wealth of practical advice for researchers who are new to the technology. This volume is authored by an interdisciplinary team of VR researchers including computer scientists, engineers, psychologists and neuroscientists. It highlights current research in the field to demonstrate how VR advances our understanding of the mind, while also providing groundbreaking solutions in applied domains.
    Type of Medium: Online Resource
    Pages: X, 387 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031429958
    Series Statement: Current Topics in Behavioral Neurosciences, 65
    DDC: 612.8
    Language: English
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