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  • 1
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Translational Neuroscience of Speech and Language Disorders: State of the Art. -2. Translational Neuroscience of Aphasia and Adult Language Rehabilitation. -3. Treatment and intervention approaches for the improvement of language abilities in neurodegenerative diseases -- 4. Neural and Genetic Mechanisms of Dyslexia -- 5. The role of memory systems in neurodevelopmental disorders of language -- 6. Transcranial direct current stimulation (tDCS) and Language/Speech: Can patients benefit from a combined therapeutic approach? -- 7. Transcranial Magnetic Stimulation in Aphasia Rehabilitation -- 8. The Cerebellum: A Therapeutic Target in Treating Speech and Language Disorders -- 9. Navigated rTMS for Mapping the Language Network in Preoperative Settings: Current Status and Future Prospects -- 10. Presurgical Language fMRI in Epilepsy: An Introduction -- 11. Lesion-symptom mapping in speech and language disorders: a translational perspective.
    Kurzfassung: This edited volume provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative conditions on speech and language. It brings together contributions from several leading experts in a markedly broad range of disciplines, including Speech and Language Therapy, Neuropsychology and Neurology, but also Neurosurgery, Neuroimaging and Neurostimulation, as well as Engineering and Genetics.
    Materialart: Online-Ressource
    Seiten: XVII, 290 p. 18 illus., 8 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030356873
    Serie: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Anatomy. ; Internal medicine. ; Cytology. ; Biochemistry. ; Neuroscience. ; Anatomy. ; Internal Medicine. ; Cell Biology. ; Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Neurosecretion: A Historical Overview -- Neurosecretion: Hypothalamic Somata versus Neurohypophysial Terminals -- Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus -- Somato-Dendritic Secretion of Neuropeptides -- Neurosecretory Vesicles: Structure, Distribution, Release and Breakdown -- Molecular Controls on Regulated Neurotransmitter and Neurohormone Secretion -- Secretory Astrocytes -- Action Potential-Induced Ca2+ Influx for Both Acute and Sustained Insulin Secretion in Pancreatic Beta Cells -- Plasticity in the Morphology of Lactotrophs and Folliculo-Stellate Cells and Prolactin Secretion -- Neuroendocrine and Metabolic Regulation of Plasma Growth Hormone Secretory Profiles -- Role of the TWIK-Related Potassium (TREK)-1 Channels in the Regulation of Adrenocorticotropic Hormone (ACTH) Secretion from Pituitary Corticotropes -- How Do Bacterial Neurotoxins Affect Neurosecretion? -- Secretory Mechanisms in Paramecium.
    Kurzfassung: How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley.
    Materialart: Online-Ressource
    Seiten: XIII, 307 p. 65 illus., 43 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030229894
    Serie: Masterclass in Neuroendocrinology, 8
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Schlagwort(e): Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Beschreibung / Inhaltsverzeichnis: Ch 1: Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging -- Ch 2: Genetic and Molecular Aspects of the Aging Auditory System -- Ch 3: The Aging Cochlea and Auditory Nerve -- Ch 4: Age-Related Changes in the Auditory Brainstem and Inferior Colliculus -- Ch 5: Age related changes in the primate auditory cortex -- Ch 6: The Aging Auditory System: Electrophysiology -- Ch 7: Age-Related Changes in Segregation of Sound Sources -- Ch 8: Causes and Consequences of Age-Related Hearing Loss -- Ch 9: Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences -- Ch 10: Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener -- Ch 11: Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention -- Ch 12: Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss.
    Kurzfassung: This volume provides contemporary discussions on new developments in aging research. It serves as an important update on the current state of research on the aging auditory system. Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging Karen S. Helfer and Edward L. Bartlett Genetic and Molecular Aspects of the Aging Auditory System Shinichi Someya and Mi-Jung Kim The Aging Cochlea and Auditory Nerve Kevin K. Ohlemiller and Christopher Spankovich Age-Related Changes in the Auditory Brainstem and Inferior Colliculus Josef Syka Age-Related Changes in the Primate Auditory Cortex Gregg Recanzone The Aging Auditory System: Electrophysiology Kelly C. Harris Age-Related Changes in Segregation of Sound Sources Frederick J. Gallun and Virginia Best Causes and Consequences of Age-Related Hearing Loss Jennifer A. Deal, Nicholas S. Reed, Emily C. Pedersen, and Frank R. Lin Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences Sandra Gordon-Salant, Maureen J. Shader, and Arthur Wingfield Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener Stefanie E. Kuchinsky and Kenneth I. Vaden, Jr. Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention Larry E. Humes, M. Kathleen Pichora-Fuller, and Louise Hickson Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss Robert D. Frisina, Carlos J. Cruz, Tanika T. Williamson, Xiaoxia Zhu, and Bo Ding .
    Materialart: Online-Ressource
    Seiten: XVII, 323 p. 62 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030493677
    Serie: Springer Handbook of Auditory Research, 72
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Schlagwort(e): Neurosciences. ; Biomedical engineering. ; Nanotechnology. ; Biophysics. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Nanoengineering. ; Bioanalysis and Bioimaging. ; Biological Imaging.
    Beschreibung / Inhaltsverzeichnis: Part 1 -- Optically-Pumped Magnetometers Compatible with Large Transient Magnetic Fields -- Small animal biomagnetism applications -- Supine OPM-MEG in Multi-layer Cylindrical Shield -- Ambulatory MEG Arrays -- Part 2 -- "Tri-axial helium-4 optically-pumped -- magnetometers for MEG" -- Person-Sized Magnetoencephalography Systems with Optically Pumped Magnetometers -- On-scalp MEG with High-Tc SQUIDs -- "Fiber Coupled OPM in Purely Coil -- Shielded Environment" -- SERF-OPM usability for MEG in two-layer shielded rooms -- Turning OPM-MEG into a Wearable Technology -- Part 3 -- OPM Gradiometer for Magnetorelaxometry -- Unshielded High Bandwidth Magnetorelaxometry of Magnetic Nanoparticles with Optically Pumped Magnetometers -- Adult Magnetocardiography: Principles and Clinical Practice -- Fetal Magnetocardiography with OPMs -- Emerging MR sensors for biomagnetic measurements -- Index.
    Kurzfassung: This contributed volume reviews the latest advances in all the new technologies currently developed for MagnetoEncephaloGraphy (MEG) recordings, as well as sensor technologies and integrated sensor arrays for on-scalp MEG. The book gives an account of the first MEG imaging studies and explores the new field of feasible, experimental paradigms of on-scalp MEG. This is an ideal book for engineers, researchers, and students in the neurosciences interested in MEG imaging. .
    Materialart: Online-Ressource
    Seiten: IX, 315 p. 104 illus., 88 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031053634
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction Food and Brain -- 2. Food and Behavior -- 3. Food and Psychological Wellbeing -- 4. Food and Cognition -- 5. Autism and Food -- 6. Healthy Brains: Types of Food and their Active Pharmacological Ingredients -- 5. Dieting: Importance of Diet and Diet Types -- 6. Nutrigenomics -- 7. Epigenetics -- 8. Gut Microbiota (microbiome) -- 9. Personalized Nutrition -- 10. Vegetables -- 11. Fruits -- 12. Nuts, Seeds and Spices -- 13. Grains [Oats, Barley & Quinoa] -- 14. Seafood [fish like Salmon, Oyster, Sea vegetables (algae)] -- 15. Other -- 16. Autism Management through Food and Diet -- 17. Personalized Nutrition Therapy.
    Kurzfassung: The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.
    Materialart: Online-Ressource
    Seiten: XX, 693 p. 111 illus., 68 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030304027
    Serie: Advances in Neurobiology, 24
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Pharmacology. ; Anesthesiology. ; Neuroscience. ; Pharmacology. ; Anesthesiology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Analgosedation -- Chapter 2. Inhalational Anesthetics -- Chapter 3. Intravenous Anesthetic Agents -- Chapter 4. Local Anesthetics -- Chapter 5. Neuromuscular Blocking Drugs (nmbds) -- Chapter 6. Reversal Agents and Antagonists -- Chapter 7. Anticholinergics -- Chapter 8. Anti-epileptic Drugs (aeds) -- Chapter 9. Osmotherapy -- Chapter 10. Antibiotics -- Chapter 11. Anti-viral -- Chapter 12. Antifungal -- Chapter 13. Anticoagulants and Antiplatelets -- Chapter 14. Glucocorticoids -- Chapter 15. Antihypertensives -- Chapter 16. Vasopressors -- Chapter17. Antipsychotics -- Chapter 18. Miscellaneous drugs. .
    Kurzfassung: The pharmacodynamics and pharmacokinetics of several drugs is expected to be known to clinicians and researchers at all times. With advances in sciences and development of newer drugs very frequently, it is very important to keep your knowledge updated at all times. This title is a quick guide to researchers and clinicians for a quick reference. The title is also a vital resource for all streams of neurosciences (neuroanesthesia and neurointensive care) and is much different from a conventional pharmacology titles, being more reader friendly and to the point facilitated with numerous flowcharts and algorithms with each chapter being prepared in a standard structured manner.
    Materialart: Online-Ressource
    Seiten: VII, 1074 p. 331 illus., 108 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811535918
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Animal culture. ; Veterinary medicine. ; Neuroscience. ; Animal Science. ; Veterinary Science.
    Beschreibung / Inhaltsverzeichnis: Rodents -- Carnivores -- Sheep and goats -- Swine -- Rabbits -- Bovines -- Non-human primates -- Humans -- Squirrels.
    Kurzfassung: Modern neuroscience has presented new opportunities for exploring the molecular and neural mechanisms controlling specific social responses. This book reviews insights into the neural circuits underlying a particularly fascinating form of social interaction, parental behavior. This book presents a detailed review of maternal and paternal behavior of particular mammalian species. It offer neuroscientists a spectrum of specific mammals that can be used as experimental models to explore particular topics on the functions of the nervous system. It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild. It also discusses the implications of this research for human parental behavior. .
    Materialart: Online-Ressource
    Seiten: V, 309 p. 45 illus., 39 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030977627
    Serie: Advances in Neurobiology, 27
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Kurzfassung: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Materialart: Online-Ressource
    Seiten: XIV, 256 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811943249
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Neurology . ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Neuroscience. ; Neurology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Sleep: Basic and Historical Aspects -- Sleep: Findings in Invertebrates and Lower Vertebrates -- Sleep: Evolutionary and Adaptive Changes in Birds and Mammals -- Sleep Loss: What Does it do to our Brain and Body -- Sleep: Neural Optimization as An Ultimate Function for Memory Consolidation -- Sleep: Disorders and Clinical Implications.
    Kurzfassung: This book discusses the evolution of sleep and its possible function in the higher invertebrates and vertebrates, including humans. It describes the current concept of sleep and its functions, based on research on the mammalian system. To date, electrophysiological recordings of the brain waves, muscle activity, and eye movements are the only tools available for characterizing the sleep architecture in the majority of animals. In mammals and birds, only two distinct types of sleep are found – non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. Since the discovery of REM sleep, studies have been performed to understand the purpose of the two distinct sleep states in higher vertebrates (birds and mammals), and how REM sleep was evolved. The book summarizes the role of both REM and NREM sleep in the proper functioning of the brain and body. It covers various aspects of the role of sleep in important physiological processes, including memory consolidation, induction of synaptic plasticity, energy restoration, enhancing immune response, and maturation of neuronal circuitries during early life. Lastly, the book reviews the effects of chronic/acute sleep deprivation on memory consolidation, obesity, and the immune system in animal models and humans.
    Materialart: Online-Ressource
    Seiten: XIV, 118 p. 30 illus., 26 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811571756
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Medicine Research. ; Biology Research. ; Psychology. ; Neuroscience. ; Biomedical Research. ; Behavioral Sciences and Psychology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Neural Circuits Underlying Innate Fear -- Chapter 2: Neurobiology and Neural Circuits of Aggression -- Chapter 3: Neural Regulation of Feeding Behavior -- Chapter 4: Neural Circuits for Reward -- Chapter 5: Neuronal response and behavioral modulation in social interaction -- Chapter 6: Neural circuit mechanisms that underlie parental care -- Chapter 7: Spatial navigation -- Chapter 8: Neural circuits for sleep-wake regulation.
    Kurzfassung: This book summarizes the latest research findings in the neurocircuitry of innate behaviors, covering major topics such as innate fear, aggression, feeding, reward, social interaction, parental care, spatial navigation, and sleep-wake regulation. For decades, humans have been fascinated by wild animals’ instincts, like the annual two-thousand-mile migration of the monarch butterfly in North American, and the “imprint” behavior of newborn birds. Since these instincts are always displayed in stereotypical patterns in most individuals of a given species, the neural circuits processing such behaviors must be genetically hard-wired in the brain. Recently, with the development of modern techniques, including optogenetics, retrograde and anterograde virus tracing, and in vivo calcium imaging, researchers have been able to determine and dissect the specific neural circuits for many innate behaviors by selectively manipulating well-defined cell types in the brain. This book discusses recent advances in the investigation of the neural-circuit mechanisms underlying innate behaviors.
    Materialart: Online-Ressource
    Seiten: IX, 112 p. 13 illus., 10 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811570865
    Serie: Advances in Experimental Medicine and Biology, 1284
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 11
    Schlagwort(e): Neurosciences. ; Neurology . ; Neuroscience. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: PART 1: WAKEFULNESS -- Chapter 1. Exploring Oscillations in Expert Sensorimotor Anticipation: the Tennis Return of Serve -- Chapter 2. Theta Rhythm in Hippocampus and Cognition -- Chapter 3. Oscillations and Synchrony in Attention -- Christian Keitel, Gregor Thut, and Joachim Gross -- Chapter 4. Pathological High-Frequency Oscillations in Mesial Temporal Lobe Epilepsy -- PART TWO: SLEEP -- Chapter 5. Cellular Mechanisms of Thalamocortical Oscillations in the Sleeping Brain -- Chapter 6. Neuroimaging of Brain Oscillations During Human Sleep -- Chapter 7. A Role for Neuronal Oscillations of Sleep in Memory and Cognition -- Chapter 8. Sleep Oscillations and Aging -- Chapter 9. Sleep Oscillations and Psychiatric Disorders.
    Kurzfassung: This edited volume reviews recent findings that highlight the mechanisms and functions of the neuronal oscillations that structure brain activity across the sleep-wake cycle. An increasing number of studies conducted in humans and animals use a variety of techniques, ranging from intracellular recording to functional neuroimaging, that provide important insight into the mechanisms and functional properties of these brain rhythms. This book explores how the studies of these rhythms are fundamental not only for basic neuroscience, but also for clinical neuroscience. At the basic science level, neuronal oscillations shape the interactions between different areas of the brain and profoundly impact neural responses to the environment, thereby mediating the processing of information in the brain. At the clinical level, brain oscillations are affected in numerous neurological conditions and might provide useful biomarkers that inform about patients’ evolution and vulnerability. During sleep, these brain rhythms could provide functional support to internal states that govern the basic maintenance of local circuit and systemic interactions. During wake, the rhythmicity of cortical and subcortical circuits have been linked with sensory processing, cognitive operations, and preparation for action.This volume attempts to link together these sleep and wake functional roles at the level of neuroimaging and electroencephalographic measures, local field potentials, and even at the cellular level. .
    Materialart: Online-Ressource
    Seiten: XXI, 277 p. 40 illus., 24 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9781071606537
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 12
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Semiotics. ; Communication. ; Ethnology. ; Social sciences. ; Humanities. ; Behavioral Neuroscience. ; Semiotics. ; Media and Communication. ; Ethnography. ; Humanities and Social Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Bateson, Cybernetics, and Nonverbal Communication -- Chapter 2: Analog and Digital Communication, and Similar Contrasts -- Chapter3: The Slash Mark: Gregory Bateson’s Cybernetic Semiotic -- Chapter4: Intention Movements and Peacemaking Ceremonies -- Chapter5: Relational Communication in Octopus -- Chapter6: Cuban Missile Crisis -- Chapter7: False and True Lessons from the Cuban Missile Crisis -- Chapter8: A Level too Low.
    Kurzfassung: This book develops Gregory Bateson’s ideas regarding “communication about relationship” in animals and human beings, and even nations. It bases itself on Bateson’s theory of relational communication, as he described it in the zoosemiotics of octopus, mammals, birds, and human beings. This theory includes, for example, the roles of metaphor, play, analog and digital communication, metacommunication, and Laws of Form. It is organized around a letter from Gregory Bateson to his fellow cybernetic thinker Warren McCulloch at the time of the Cuban Missile Crisis. In this letter Bateson argued that what we would today call zoosemiotics, including Bateson’s own (previously unpublished) octopus research, should be made a basis for understanding the relationship between the two blocs of the Cold War. Accordingly the book shows how Bateson understood interactive processes in the biosemiotics of conflict and peacemaking, which are analyzed using examples from recent animal studies, from primate studies, and from cultural anthropology. The Missile Crisis itself is described in terms of Bateson’s critique of game theory which he felt should be modified by an understanding of the zoosemiotics of relational communication. The book also includes a previously unpublished piece by Gregory Bateson on wolf behavior and metaphor/ abduction.
    Materialart: Online-Ressource
    Seiten: XIX, 189 p. 7 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030521011
    Serie: Biosemiotics, 20
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 13
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Endocrine glands. ; Neuroscience. ; Endocrine System.
    Beschreibung / Inhaltsverzeichnis: Photoperiodism and Circannual Timing: Introduction and Historical Perspective.-The Pars Tuberalis and Seasonal Timing -- Tanycytes and Their Pivotal Role in Seasonal Physiological Adaptations -- Epigenetic Mechanisms in Developmental and Seasonal Programs -- Plasticity of Neuroendocrine Mechanisms Regulating Seasonal Reproduction in Sheep -- Clocks and Calendrars in Birds -- Calendar Timing in Teleost Fish -- Action of Light on the Neuroendocrine Axis -- Seasons, Clocks, and Mood -- Photoperiodic Modulation of Clock Gene Expression in the SCN -- Circadian Timekeeping in the Suprachiasmatic Nucleus: Genes, Neurotransmitters, Neurons and Astrocytes. .
    Kurzfassung: This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of “clock“ gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. .
    Materialart: Online-Ressource
    Seiten: XII, 244 p. 64 illus., 58 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030556433
    Serie: Masterclass in Neuroendocrinology, 10
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 14
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Kurzfassung: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Materialart: Online-Ressource
    Seiten: XV, 624 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811676062
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 15
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Stem cells. ; Nervous system Regeneration. ; Neuroscience. ; Stem Cell Biology. ; Regeneration and Repair in the Nervous System.
    Beschreibung / Inhaltsverzeichnis: 1 Regenerative Therapies in Ischemic Stroke Recovery -- 2 Application of Nanotechnology In Stroke Recovery -- 3 Nanotechnology: A daydream for advanced Imaging, Diagnosis and Therapeutic Approach for Cerebral Ischemia -- 4 Cell-Mediated Neurorestorative Mechanisms Underpinning Beneficial Effects in Ischemic Stroke -- 5 Induced Pluripotent Stem Cells for the Treatment of Neurodegenerative Disease: Current and Future Prospects -- 6 Imaging of Stem Cell Therapy for Stroke and Beyond -- 7 Nano-Medicine Mediated Stem Cell Therapeutics In Stroke -- 8 The Influence of Preconditioning on the Homing Behaviour of Stem Cells -- 9 Role of microRNAs in stroke pathology and recovery -- 10 Exosomes as a diagnostic tool and stem cells exosomes as a promising cell-based cell-free therapeutic tool for ischemic stroke 11 Role of nanomedicine in treating ischemic stroke -- 12 Insights into therapeutic targets in stroke -- 13 Signalling Pathways of Interest for Recovery from Ischemic Stroke.
    Kurzfassung: This book illustrates the importance and significance of regenerative medicine in stroke recovery. It discusses stem-cell-based treatment strategies and offers mechanistic insights into their role in neurological recovery. It also examines the challenges and advances in using adult stem cells for enhanced therapeutic efficacy. Further, it presents the strategies as well as the strengths and weaknesses of various delivery methods to administer stem cells in ischemic stroke. It examines the role of non-coding RNA in our understanding the stroke pathogenesis, their regulatory role in ischemic stroke and potential as biomarkers and therapeutic targets. Lastly, it explores exosomes in the treatment of stroke, and the underlying mechanism of their action as therapeutic vectors for stroke. Given its scope, it is an excellent resource for neurologists, neuroscientists and researchers involved in regenerative therapy for stroke.
    Materialart: Online-Ressource
    Seiten: XIII, 353 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811685620
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 16
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Cognitive neuroscience. ; Social evolution. ; Neuroscience. ; Cognitive Neuroscience. ; Social Evolution.
    Beschreibung / Inhaltsverzeichnis: Part I Differentiation-Integration Dynamics: Ultimate Causes -- Chapter 1: Introduction -- Chapter 2: Purposeless Design -- Chapter 3: Darwinian Evolutionary Theory -- Chapter 4: Principles of Differentiation and Integration -- Chapter 5: The Information Trend in Science -- Chapter 6: Is Social Cohesion a Different Mechanism of Evolution? -- Part II Roots and Mechanisms: Proximate Causes -- Chapter 7: Fundamental Physical Forces, Genes, and Epigenetics -- Chapter 8: Biological Origins -- Chapter 9: Neural Mechanisms of Sociality -- Chapter 10: Psychological Features -- Chapter 11: Cognitive Science Underpinnings -- Chapter 12: A Sociological Systems Theory -- Chapter 13: Developmental Roots -- Chapter 14: Metaphysical, Religious, and Spiritual Aspects -- Part III Survival Value -- Chapter 15: Sociality’s Survival Value -- Part IV Conclusions -- Chapter 16: A New Framework: A Theory of Integration.
    Kurzfassung: This book is an exploration of the integration-differentiation dynamics that result in a drive, or impulse, toward human sociality, arguing that our need to connect with other people is as fundamental as our need for food and shelter. In The Social Impulse: The Evolution and Neuroscience of What Brings Us Together, Jaime Pineda presents the evidence that social cohesion is a complementary force to natural selection, the Darwinian drive for differentiation and diversity. The book addresses the distinctive aspects of social behavior that arise from integration principles and seeks to answer the following questions: (1) Why does social cohesion arise? (2) What is the history of social dynamics? (3) How does social cohesion work? (4) When do the developmental aspects of social dynamics arise? A final section of the book addresses the value of sociality and social cohesion. By exploring the differences, similarities, and, most important, the interactivity between natural selection and social cohesion, this unique book provides a wealth of interesting, challenging, and unexpected insights.
    Materialart: Online-Ressource
    Seiten: XXV, 190 p. 7 illus., 6 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031084393
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 17
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Pain medicine. ; Clinical psychology. ; Neuroscience. ; Pain Medicine. ; Clinical Psychology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Conceptualising Pain in Critically-Ill Neonates or Infants -- Chapter 2. Pain in the Fetus and the Preterm Baby -- Chapter 3. Developmental Influences on the Meanings of Pain in Children -- Chapter 4. “Ooh, You Got to Holler Sometime:” Pain Meaning and Experiences of Black Older Adults -- Chapter 5. Exploring the Meaning of Chronic Low Back Pain as a Life of ‘Living Death’ in Rural Nigeria -- Chapter 6. Painworld: A Phenomenological View of Veteran Experiences of Living with Chronic Pain -- Chapter 7. “It’s Just One of Them Things You’ve Got to Try and Manage”: Meanings of Pain for People with Brain Injury.
    Kurzfassung: This book, the third and final volume in the Meaning of Pain series, describes what pain means to people with pain in “vulnerable” groups, and how meaning changes pain – and them – over time. Immediate pain warns of harm or injury to the person with pain. If pain persists over time, more complex meanings can become interwoven with this primitive meaning of threat. These cognitive meanings include thoughts and anxiety about the adverse consequences of pain. Such meanings can nourish existential sufferings, which are more about the person than the pain, such as loss, loneliness, or despair. Although chronic pain can affect anyone, there are some groups of people for whom particular clinical support and understanding is urgently needed. This applies to “vulnerable” or “special” groups of people, and to the question of what pain means to them. These groups include children, women, older adults, veterans, addicts, people with mental health problems, homeless people, or people in rural or indigenous communities. Several chapters in the book focus on the lived experience of pain in vulnerable adults, including black older adults in the US, rural Nigerians, US veterans, and adults with acquired brain injury. The question of what pain experience could mean in the defenceless fetus, neonate, pre-term baby, and child, is examined in depth across three contributions. This book series aspires to create a vocabulary on the “meanings of pain” and a clinical framework with which to use it. It is hoped that the series stimulates self-reflection about the role of meaning in optimal pain management. Meanings of Pain is intended for people with pain, family members or caregivers of people with pain, clinicians, researchers, advocates, and policy makers. Volume I was published in 2016; Volume II in 2019.
    Materialart: Online-Ressource
    Seiten: VII, 147 p. 5 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030958251
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 18
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Materials Analysis. ; Imaging systems. ; Nervous system Diseases. ; Nervous system Radiography. ; Neuroscience. ; Imaging Techniques. ; Neurological Disorders. ; Neuroradiology.
    Beschreibung / Inhaltsverzeichnis: Optical coherence tomography in brain gliomas detection and peritumoral white matter state evaluation -- Two Photon Fluorescence Lifetime Imaging of Reduced nicotinamide adenine dinucleotide in Brain Research -- Types of Raman Scattering Techniques for Neurodegenerative Diseases -- Drosophila brain advanced multiphoton imaging -- Myelin imaging -- Brainbow: Principle, Technique and Applications -- Photoacoustic Imaging of Brain -- Photodynamic therapy of brain diseases -- Advanced Magnetic Resonance Imaging (MRI) of Brain -- Indirect imaging -- Multimodal Noninvasive Imaging Strategies for Clinically Monitoring Degenerative Disorders of the Brain -- Machine learning approach in brain imaging -- Transgenic Brain mapping Techniques in Drosophila melanogaster -- Behavioural phenotyping to study cognitive and non-cognitive symptoms in the rodent model of Alzheimer's disease.
    Kurzfassung: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.
    Materialart: Online-Ressource
    Seiten: XII, 257 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811913525
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 19
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. The Auditory Cognitive Neuroscience of Speech Perception in Context -- 2. Subcortical Processing of Speech Sounds -- 3. Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology -- 4. A Parsimonious Look at Neural Oscillations in Speech Perception -- 5. Extracting Language Content From Speech Sounds: The Information Theoretic Approach -- 6. Speech Perception under Adverse Listening Conditions -- 7. Adaptive Plasticity in Perceiving Speech Sounds -- 8. Development of Speech Perception -- 9. Interactions Between Audition and Cognition in Hearing Loss and Aging.
    Kurzfassung: This volume reviews contemporary developments in the auditory cognitive neuroscience of speech perception, including both behavioral and neural contributions. It serves as an important update on the current state of research in speech perception. The Auditory Cognitive Neuroscience of Speech Perception in Context Lori L. Holt, and Jonathan E. Peelle Subcortical Processing of Speech Sounds Bharath Chandrasekaran, Rachel Tessmer, and G. Nike Gnanateja Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology Yulia Oganian, Neal P. Fox, and Edward F. Chang A Parsimonious Look at Neural Oscillations in Speech Perception Sarah Tune, and Jonas Obleser Extracting Language Content From Speech Sounds: The Information Theoretic Approach Laura Gwilliams, and Matthew H. Davis Speech Perception under Adverse Listening Conditions Stephen C. Van Hedger, and Ingrid S. Johnsrude Adaptive Plasticity in Perceiving Speech Sounds Shruti Ullas, Milene Bonte, Elia Formisano, and Jean Vroomen Development of Speech Perception Judit Gervain Interactions Between Audition and Cognition in Hearing Loss and Aging Chad S. Rogers, and Jonathan E. Peelle .
    Materialart: Online-Ressource
    Seiten: XVI, 252 p. 33 illus., 29 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030815424
    Serie: Springer Handbook of Auditory Research, 74
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 20
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Behavioral Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Part I Preclinical Research: Neuroendocrine Mechanisms of Social Bonds and Separation Stress in Rodents, Dogs, and Other Species -- Methods and Challenges in Investigating Sex-Specific Consequences of Social Stressors in Adolescence in Rats: Is It the Stress or the Social or the Stage of Development?- Social stress-induced neuroinflammation and mitochondrial dysfunction as a link to depression and cardiovascular disease comorbidity -- Mean Girls: Social Stress Models for Female Rodents -- Development of Mixed Anxiety/ Depression-Like State as a Consequence of Chronic Anxiety: Review of Experimental Data -- Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse -- Social Stress and Aggression in Murine Models -- More or less: glucocorticoid roles in aggression -- Neurobiological Bases of Urges for Alcohol Consumption After Social Stress -- Epigenetics of Aggression -- Part II Human Research: Early Life Stress and Neurodevelopment in Adolescence: Implications for Risk and Adaptation -- Effects of Parenting Environment on Child and Adolescent Social-Emotional Brain Function -- The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans -- Social Acts and Anticipation of Social Feedback -- Clinical Outcomes of Severe Forms of Early Social Stress -- Childhood Violence Exposure, Inflammation, and Cardiometabolic Health -- Social Support Effects on Neural Stress and Alcohol Reward Responses -- Neural Underpinnings of Social Stress in Human Addiction.
    Kurzfassung: Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
    Materialart: Online-Ressource
    Seiten: VIII, 515 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031042560
    Serie: Current Topics in Behavioral Neurosciences, 54
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 21
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Psychiatry. ; Neuroscience. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Section I. Anhedonia – History, Etiology, and Assessments -- 1. Historical Perspective -- 2. Clinical and Behavioral Assessments -- 3. Developmental Trajectories: Preclinical -- 4. Developmental Trajectories: Clinical -- 5. Genetics Contributions -- 6. Environmental Contributions -- Section II. Anhedonia in Psychiatric and Neurological Disorders -- 7. Depression and Bipolar Disorder -- 8. Schizophrenia -- 9. Substance Use Disorder -- 10. Nicotine Dependence -- 11. Posttraumatic Stress Disorder -- 12. Anxiety -- 13. Eating Disorders -- 14. Autism and Developmental Disorders -- 15. Neurodegenerative Disorders -- Section III. Reward Processing Systems in Anhedonia -- Reward Responsiveness -- 16. Pleasure -- 17. Anticipation -- Reward Valuation -- 18. Reward Value – Delay and Reward Magnitude -- 19. Effort/Motivation -- Reward Learning -- 20. Reward Prediction Error -- 21. Probabilistic and Reinforcement Learning -- Section IV. Treatments -- 22. Pharmacological Treatments for Anhedonia -- 23. Psychological Treatments for Anhedonia -- 24. Neurostimulation -- Section V. Special Topics -- 25. Inflammation and Anhedonia -- 26. Computational Modeling of Anhedonia -- 27. Anhedonia and Suicide.
    Kurzfassung: Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.
    Materialart: Online-Ressource
    Seiten: XI, 535 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031096839
    Serie: Current Topics in Behavioral Neurosciences, 58
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 22
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Animal migration. ; Biology Technique. ; Physiology. ; Behavioral Neuroscience. ; Animal Migration. ; Experimental Organisms. ; Animal Physiology.
    Beschreibung / Inhaltsverzeichnis: Preface -- Chapter 1. Studying Birds -- Chapter 2. Mapping Sentences and Facet Theory -- Chapter 3. How to Develop a Mapping Sentence: The Example of Avian Sleep -- Chapter 4. Complex Avian Behaviour and Cognition: A Mapping Sentence Approach -- Chapter 5 -- Studying Avian Cognition in the Wild: Avian Psychometrics -- Chapter 6. Interpreting Avian Play, Murmuration of Starlings and Oology (Classifying Birds' Eggs) -- Chapter 7. Conclusion -- Glossary -- Index.
    Kurzfassung: This book presents the facet theoretical framework as a tool for facilitating the conception of complex animal behaviour research and the design of research procedures through employing mapping sentences. Using the facet theoretical framework, this book takes a holistic view of bird behaviour. Components of bird behavior are identified and then reassembled to facilitate an understanding of the behaviour in the context of its natural occurrence. This provides new insight on both the parts of the behaviour and how these interact as a whole. The multi-faceted approach to designing, evaluating and understanding bird behavior presented offers a template that is adaptable for investigating a wide variety of avian species and different forms of behaviour. Behavioural biologists, animal and comparative psychologists, other natural and behavioural scientists, as well as students of these disciplines will find this book to be an interesting and enlightening read.
    Materialart: Online-Ressource
    Seiten: XXXVII, 203 p. 29 illus., 6 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030121921
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 23
    Schlagwort(e): Neurosciences. ; Medical genetics. ; Immunology. ; Cell death. ; Cytology. ; Stress (Physiology). ; Neuroscience. ; Medical Genetics. ; Immunology. ; Cell Death. ; Cellular Stress.
    Beschreibung / Inhaltsverzeichnis: Preface -- Chapter 1: microRNAs in normal brain physiology -- Chapter 2: Ischemic stroke: An imperative need for effective therapy -- Chapter 3: MicroRNAs in ischemic stroke pathophysiology: Special emphasis on early molecular events -- Chapter 4: microRNA regulation of ischemic stroke inflammatory and immune response -- Chapter 5: Regulatory role of microRNAs in ischemic cell death -- Chapter 6: The emerging role of microRNAs in post-ischemic angiogenesis and neurogenesis -- Chapter 7: MicroRNAs as potential diagnostic, prognostic and therapeutic biomarkers in ischemic stroke -- Chapter 8: Interplay between microRNAs and other cerebrovascular diseases -- Chapter 9: New insights into the regulatory role of lncRNA, circRNA, piRNAs, and ceRNAs in ischemic stroke -- Chapter 10: Computational resources for microRNA research -- Chapter 11: MicroRNA-targeted therapeutics for ischemic stroke: Status, gaps and the way forward.
    Kurzfassung: There has been an enormous increase in information relating to microRNA (miRNA) and its strategic role in numerous diseases. This book reviews the emerging role of microRNAs in cerebral ischemia, providing comprehensive details of the links between this small RNA molecule and ischemic stroke, the more prevalent of the two main types of stroke. The chapters address questions relating to microRNA’s function in various pathological features of stroke, like oxidative stress, excitotoxicity and cell death, as well as its role as a biomarker and diagnostic agent, and the current therapeutic interventions. Further, the book highlights the latest research on how miRNAs contribute to neuroregeneration following stroke, discussing the myriad computational tools and databases used in miRNA research, and decsribes how how miRNA modulates other cerebrovascular diseases. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.
    Materialart: Online-Ressource
    Seiten: XVI, 138 p. 7 illus., 6 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811547980
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 24
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Kurzfassung: This volume focuses on new molecular therapies that aim to prevent specific pathologies of the ear, like age-related hearing loss, noise-induced hearing loss and ototoxicity. The book discusses the regenerative capacity of hair cells in the inner ear, exploring the idea that hair cells’ capacity to regenerate appears “repressed” in adult mammals, but that it will be possible to re-activate regeneration with an appropriate therapeutic approach. The book provides an overview of inflammatory and immune cells in the cochlear lateral wall, the pathways involved in cochlear damage, and their potential as therapeutic targets. It also describes the significant advances in animal models which play an important role in revealing the underlying mechanisms and treatment for tinnitus and hyperacusis. Finally, the book describes two new automatic and robust measures to evaluate hearing loss and tinnitus in preclinical models.
    Materialart: Online-Ressource
    Seiten: VII, 186 p. 29 illus., 25 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030404130
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 25
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Bioethics. ; Security, International. ; Security systems. ; Neuroscience. ; Bioethics. ; International Security Studies. ; Security Science and Technology.
    Beschreibung / Inhaltsverzeichnis: 1. Modern Neuroscience -- 2. The Chemical and Biological Non-Proliferation Regime in 2018 -- 3. Neuroethics and the Regulation of Misuse -- 4. Dual-Use Neuroscience? -- 5. The EU Human Brain Project -- 6. The US BRAIN Initiative -- 7. Global Neuroethics in Early 2019 -- 8. Japan’s BRAIN/Minds Project -- 9. China’s Brain Project -- 10. Conclusion.
    Kurzfassung: After COVID-19 ensuring biological security will be a critical necessity. Neuroscience and the Problem of Dual Use focuses on the fact that benignly intended research in the life sciences could be misused for hostile purposes. It details the revolution that is taking place in neuroscience during this period of instability in international security, describes the new major State-funded brain research projects, and suggests ways in which hostile misuse could be prevented in coming decades.
    Materialart: Online-Ressource
    Seiten: XXV, 210 p. 4 illus., 3 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030537906
    Serie: Advanced Sciences and Technologies for Security Applications,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 26
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Immunology. ; Cytology. ; Neuroscience. ; Immunology. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Part 1: Visualizing and Controlling Molecules for Life -- Chapter 1. Photoacoustic Tomography: Deep Tissue Imaging by Ultrasonically Beating Optical Diffusion -- Chapter 2. Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions -- Chapter 3. Eavesdropping on Biological Processes with Multi-Dimensional Molecular Imaging -- Chapter 4. Apical microtubules define the function of epithelial cell sheets consisting of non-ciliated or multi-ciliated cells -- Chapter 5. Illuminating the brain -- Chapter 6. Optogenetic assemblies of cortical force-generating complexes during mitosis -- Chapter 7. In vivo Imaging Probes with Tunable Chemical Switches -- Chapter 8. Circuit-dependent striatal PKA and ERK signaling underlying action selection -- Chapter 9. Electrophysiology, Unplugged: New Chemical Tools to Image Voltage -- Chapter 10. Molecular dynamics revealed by single-molecule FRET measurement -- Chapter 11. Comprehensive approaches using luminescence to studies of cellular functions -- Part II: Imaging Disease Mechanisms -- Chapter 12. Make Chronic Pain Visible -- Chapter 13. Cortical plasticity after spinal cord injury using resting-state functional magnetic resonance imaging -- Chapter 14. Multimodal Label-free imaging to assess compositional and morphological changes in cells during immune activation -- Chapter 15. Investigating in vivo myocardial and coronary molecular pathophysiology in mice with X-ray radiation imaging approaches -- Chapter 16. Visualizing the Immune Response to Infections -- Chapter 17. Imaging Sleep and Wakefulness -- Chapter 18. Abnormal local translation in dendrites impairs cognitive functions in neuropsychiatric disorders -- Chapter 19. Imaging synapse formation and remodeling in vitro and in vivo -- Part III: Imaging-based Diagnosis and Therapy -- Chapter 20. How MRI makes the Brain Visible -- Chapter 21. Intravital multiphoton imaging revealing cellular dynamics in vivo -- Chapter 22. Theranostic Near Infrared Photoimmunotherapy for Cancer -- Chapter 23. Novel and integrated imaging on Chronic Fatigue -- Chapter 24. Novel fluorescent probes for rapid tumor imaging and fast glutathione dynamics -- Chapter 25. Coronary Heart Disease Diagnosis: Engineering Triumphs, Economic Barriers -- Chapter 26. Live imaging of the skin immune responses -- Chapter 27. Development of a horizontal CT and its application to musculoskeletal disease -- Chapter 28. The Future of Precision Health & Integrated Diagnostics -- Chapter 29. Imaging and therapy against hypoxic tumors with 64Cu-ATSM.
    Kurzfassung: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology in the broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license. .
    Materialart: Online-Ressource
    Seiten: IX, 292 p. 137 illus., 106 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811379086
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 27
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Human physiology. ; Neurology . ; Neuroscience. ; Human Physiology. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Neurophysiology and Respiratory system -- Chapter 2. Normal physiology of Respiratory System -- Chapter 3. Brain – Lung crosstalk.
    Kurzfassung: The central nervous system, which includes the brain and spinal cord, has a high metabolic demand. The physiology of the brain is such that it is easily affected by alterations in other systems, which in turn can compromise cerebral blood flow and oxygenation. Together the brain and spinal cord control the automatic function of our body systems. While other systems of body controls individual functions, central nervous system at the same time does many different functions, especially, controlling the function of other systems. This interaction between the brain and other systems is important when it comes to understanding how injuries to the brain can, at times, produce complications in remote organs or systems of the body, such as the lungs. This book explains the lesser-known crosstalks between acutely or chronically affected brain and lung, describing the pathophysiology of the lung following brain injury and discussing in detail the conflicts between the brain and lungs in relation to the tidal volumes, positive end-expiratory pressures, arterial carbon dioxide and oxygen levels, recruitment maneuvers and positioning, as well as potential therapeutic targets. .
    Materialart: Online-Ressource
    Seiten: XIII, 103 p. 27 illus., 26 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811523458
    Serie: Physiology in Clinical Neurosciences – Brain and Spinal Cord Crosstalks,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 28
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Modeling neurodevelopmental deficits in Tuberous Sclerosis Complex with stem cell-derived neural precursors and neurons -- 2. Advances in human stem cells and genome editing to understand and develop treatment for Fragile X syndrome -- 3. IPSC MODELS OF CHROMOSOME 15Q IMPRINTING DISORDERS: FROM DISEASE MODELING TO THERAPEUTIC STRATEGIES -- 4. Creating iPSC based models to understand the signaling and cellular phenotypes in idiopathic autism and 16p11.2 derived neurons -- 5. Dysregulation of Neurite Outgrowth and Cell Migration in Autism and other Neurodevelopmental Disorders -- 6. Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells -- 7. Modeling Inflammation on Neurodevelopmental disorders using pluripotent stem cells -- 8. Astrocyte-derived exosomes in an iPSC model of bipolar disorder -- 9. Two- and there-dimensional stem cell models to define mechanisms underlying psychiatric disorders -- 10. Development of a 3-D organoid system using human induced pluripotent stem cells to model idiopathic autism.
    Kurzfassung: This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.
    Materialart: Online-Ressource
    Seiten: IX, 305 p. 26 illus., 23 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030454937
    Serie: Advances in Neurobiology, 25
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 29
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Nutrition   . ; Quantitative research. ; Nervous system Diseases. ; Neuroimmunology. ; Neuroscience. ; Nutrition. ; Data Analysis and Big Data. ; Neurological Disorders. ; Neuroimmunology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Nutrigenomics; a broader concept -- Chapter 2. Gene-environment interaction -- Chapter 3. Gene-gut-brain - axis (gene–based personalized medicine) -- Chapter 4. Nutrigenomics of aging -- Chapter 5. Nutrigenomics and Mental health -- Chapter 6. Nutrigenomics and neurodevelopmental disorders -- Chapter 7. Nutrigenomics and Alzheimer’s disease -- Chapter 8. Nutrigenomics and Parkinson’s Disease -- Chapter 9. Nutrigenomics, nutrigenetics and big data -- Chapter 10. Nutrigenomics and Development -- Chapter 11. Early Child malnutrition and neurodevelopment -- Chapter 12. The emerging role of vit D deficiency and Parkinson’s Disease risk -- Chapter 13. Nutrigenomics and autophagy crosstalk -- Chapter 14. Nanoparticles in food additives and brain health.
    Kurzfassung: This book highlights the effect of complex interactions between numerous genetic and environmental factors, including food intake, physical activity, age, and stress on brain physiology and function. It further discusses the mechanistic connection between nutrition and aging towards understanding the effect of the brain on longevity. The book also reviews the efficiency of nutraceutical compounds for treating and preventing of neurodevelopmental and neurodegenerative disorders. It also discusses the role of gut microbiota on the gut-brain axis and presents the role of nutrition in neurological inflammatory diseases.
    Materialart: Online-Ressource
    Seiten: VII, 234 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811692055
    Serie: Nutritional Neurosciences,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 30
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Biomedical engineering. ; Neurology . ; Radiology. ; Biophysics. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Neurology. ; Radiology. ; Biophysics.
    Beschreibung / Inhaltsverzeichnis: Introduction to Neurophysiology -- Biopotential Measurements and Electrodes -- EEG Signal Processing: Theory and Applications -- Brain-Computer Interfaces -- Intracortical Brain Machine Interfaces -- Deep Brain Stimulation: Emerging Technologies and Applications -- Transcranial Magnetic Stimulation: Principles and Applications -- Transcranial Electrical Stimulation -- Optogenetics: Novel Brain Interface Technology that Originates in Bioprospecting -- Selective Chronic Recording in the Peripheral Nervous System -- Functional Magnetic Resonance Imaging -- Photoacoustic Tomography of Neural Systems -- Electrophysiological Mapping and Source Imaging -- Exploring Functional and Causal Connectivity in the Brain -- Deep Learning Models with Applications to Brain Image Analysis -- Neural Modeling -- Linear Dynamics & Control of Brain Networks -- Deciphering the Neuronal Population Code -- Machine Intelligence Based Epileptic Seizure Forecasting -- Retinal Prosthesis -- Retinal Bioengineering -- Neural Tissue Engineering -- Index.
    Kurzfassung: This third edition overviews the essential contemporary topics of neuroengineering, from basic principles to the state-of-the-art, and is written by leading scholars in the field. The book covers neural bioelectrical measurements and sensors, EEG signal processing, brain-computer interfaces, implantable and transcranial neuromodulation, peripheral neural interfacing, neuroimaging, neural modelling, neural circuits and system identification, retinal bioengineering and prosthetics, and neural tissue engineering. Each chapter is followed by homework questions intended for classroom use. This is an ideal textbook for students at the graduate and advanced undergraduate level as well as academics, biomedical engineers, neuroscientists, neurophysiologists, and industry professionals seeking to learn the latest developments in this emerging field. Advance Praise for Neural Engineering, 3rd Edition: “A comprehensive and timely contribution to the ever growing field of neural engineering. Bin He’s edited volume provides chapters that cover both the fundamentals and state-of-the-art developments by the world’s leading neural engineers." Dr. Paul Sajda, Department of Biomedical Engineering, Electrical Engineering and Radiology, Columbia University “Neural Engineering, edited by Prof. He, is an outstanding book for students entering into this fast evolving field as well as experienced researchers. Its didactic and comprehensive style, with each chapter authored by leading scientific authorities, provides the ultimate reference for the field.” Dr. Dario Farina, Department of Bioengineering, Imperial College London, London, UK "Neural Engineering has come of age. Major advances have made possible prosthesis for the blind, mind control for quadraplegics and direct intervention to control seizures in epilepsy patients. Neural Engineering brings together reviews by leading researchers in this flourishing field. Dr. Terrence Sejnowski, Salk Institute for Biolgical Studies and UC San Diego.
    Materialart: Online-Ressource
    Seiten: XVI, 699 p. 407 illus., 299 illus. in color. , online resource.
    Ausgabe: 3rd ed. 2020.
    ISBN: 9783030433956
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 31
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Medical genetics. ; Neuroscience. ; Medical Genetics.
    Beschreibung / Inhaltsverzeichnis: A hypothesis of circulated microRnas implication in high incidence of atrial fibrillation and other electrocardiographic abnormalities in cancer patients -- Central Line-associated Bloodstream Infections (CLABSI) Incidence and the role of obesity: a prospective, observational study in Greece -- Number of brain states in an N-body dynamical scenario according to the universal Bekenstein entropy bound -- Burden and sleeping disorders of family caregivers of Hemodialysis patients with Chronic Kidney Disease-End Stage. A cross-sectional study -- Quality of life in type 2 diabetes mellitus patients with neuropsychological deficits -- A framework for assessing the impact of information seeking behavior on cancer patients’ long-term prognosis -- Sleeping Disorders and Health Related Quality of Life in Hemodialysis patients with Chronic Renal Disease in Greece -- Subjective Quality of Life, Religiousness and Spiritual Experience in Greek Orthodox Christians: Data from Healthy Aging and Patients with Cardiovascular Disease -- Mini-Mental State Examination: Greek normative data stratified by age and education in a large sample of 925 community-dwelling healthy participants -- The role of the family in the care of Alzheimer patients -- Prevalence of Stroke Cases in Warangal, Telangana Region, India: A Hospital-Based Case Study -- Compliance of Patients with Acute Coronary Syndrome with treatment following their hospitalization from the Cardiac Coronary Unit -- Using a Virtual Reality Serious Game to Assess the Performance of Older Adults with Frailty -- Characteristics and survival rates in ward patients requiring evaluation by Intensivist in Greece.
    Kurzfassung: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.
    Materialart: Online-Ressource
    Seiten: X, 155 p. 10 illus., 4 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030326371
    Serie: Advances in Experimental Medicine and Biology, 1196
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 32
    Schlagwort(e): Neurosciences. ; Psychobiology. ; Human behavior. ; Pharmacology. ; Psychiatry. ; Pain medicine. ; Neuroscience. ; Behavioral Neuroscience. ; Pharmacology. ; Psychiatry. ; Pain Medicine.
    Beschreibung / Inhaltsverzeichnis: CLINICAL PROFILE AND TREATMENTS -- ADHD in children and adults: diagnosis and prognosis -- Treatment strategies -- Psychostimulants – treatment efficacy and problems -- Recent developments and future options for pharmacological treatments for ADHD -- GENETICS -- Genetics of ADHD (including CNVs) -- Genes , cognitive function and ADHD -- Epigenetics and ADHD -- CO-MORBIDITY -- ADHD and comorbid depression -- ADHD and autism -- Aggression and ADHD -- Obesity and ADHD (+ cytokines?) -- Sleep circadian rhythms and ADHD -- Substance misuse -- ASSESSING BRAIN FUNCTION / DYSFUNCTION -- EEG and ADHD (the skeptical view) -- Update on imaging – with connectivity -- Visual processing substrates for ADHD -- Cortical microstructure / connectivity -- ANIMAL AND IN VITRO STUDIES -- Critique of animal models -- Update on circuits for impulsive behaviour -- Zebrafish -- Update on DA transporter and ADHD -- Arousal, noradrenaline and ADHD -- FUTURE DIRECTIONS -- Stem cells for disease modelling -- Microbiome and ADHD -- Adult ADHD.
    Kurzfassung: New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest developments in preclinical and clinical research of Attention Deficit Hyperactivity Disorder. As well as updating key chapters that were included in an earlier edition, this volume includes some new topics that are attracting a great deal of interest and point the way to new and promising directions for future research. The chapters follow five main themes: Current perspectives on the clinical profile of ADHD and its treatment, common co-occurring conditions, neurobiological studies examining brain function and genetics, animal and in vitro studies, and future directions. This combination of topics emphasises the translational relevance and validity of preclinical research so as to enable a better understanding of ADHD and to highlight the promising strategies for developing new treatments.
    Materialart: Online-Ressource
    Seiten: VIII, 501 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031118029
    Serie: Current Topics in Behavioral Neurosciences, 57
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 33
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Nervous system Diseases. ; Cognitive neuroscience. ; Developmental neurobiology. ; Nutrition   . ; Neuroscience. ; Neurological Disorders. ; Cognitive Neuroscience. ; Development of the Nervous System. ; Nutrition.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Micronutrients and Neurogenesis -- Chapter 2. Vit-E and Cognitive functions: What is the Interplay? -- Chapter 3. Microbiome and micronutrients -- Chapter 4. Iodine and Brain -- Chapter 5. Tocotrienol and Brain -- Chapter 6. Micronutrients and Depression -- Chapter 7. Micronutrients and Epilepsy -- Chapter 8. Iron Deficiency and brain cognitive functions -- Chapter 9. Micronutrients and PD -- Chapter 10. Malnutrition of Micronutrients and the brain disorders -- Chapter 11. Connections between micronutrients, cerebral monoamines and related brain disorders -- Chapter 12. Micronutrients and Autism -- Chapter 13. Edible Bird’s Nest as Brain Food -- Chapter 14. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Traumatic Brain Injury? -- Chapter 15. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Alzheimer’s Disease? -- Chapter 16. Nutrigenomics and Brain.
    Kurzfassung: This book comprehensively reviews the relationship between micronutrients and brain in health and diseases. It explains the relationship between micronutrients and brain functions, neurogenesis, and cognitive functions. The book also explores the relationship between micronutrients and brain disorders including depression, epilepsy, PD, and Autism. It further explores the recent advancements in understanding the important role of micronutrients as therapeutics in various brain disorders like TBI and AD. Lastly, it presents an overview of micronutrients as neuroprotective agents along with the main principles of nutrigenomics.
    Materialart: Online-Ressource
    Seiten: XVII, 308 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811664670
    Serie: Nutritional Neurosciences,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 34
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Cognitive psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of mind. ; Neurology . ; Neuroscience. ; Cognitive Psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of Mind. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Learning the Languages -- Humanity’s Search for Mind and the Subject: A Brief Review of the Evolution of Neuropsychobiology -- An “Ideographic,” Suprapersonal Language of Rules and Universal Symbols: Alwyn Scott and Nonlinear Dynamics -- A “Demotic,” First-Person Language of the Individual and the Social System: Apuleius and the Myth of Psyche -- The Language of the Objective Observer: Gerald Edelman and Neurodarwinism: Antonio Damasio and the Feeling of Knowing -- Seeking the Understanding -- Consciousness -- The Unconscious -- The Database -- Affectivity -- The Neural/Mental Gap: Intuition, Self and Ego, a Trilingual Map -- Applying the Knowledge -- The Three Languages and Science: A New Scientific Paradigm? -- The Three Languages and Treatment -- The Psychotherapeutic Dialogue: Intersubjectivity -- The Role of a New Science for Psyche Upon Society and Culture.
    Kurzfassung: The study of the brain-mind complex has been hampered by the dichotomy between objective biological neuroscience and subjective psychological science. The two antithetical avenues of research are partly responsible for the failure to unravel the transformation of neural events into mental images: how matter becomes imagination, and vice versa; is the brain’s consciousness equivalent to Ego consciousness? Is the ego the self? In its new and updated edition, “The Rosetta Stone of the Human Mind: Three Languages to Integrate Neurobiology and Psychology” illustrates how the simultaneous use of the languages of neurobiology, of mathematics, and of the humanities, enriches the understanding of the neural and mental realms and adds new dimensions to our perception of neuropsychological events. Dr. Sanguineti shows how the two seemingly dichotomous approaches are similar in what they describe, and he explores how the awareness and application of these perspectives are helpful in getting a deeper theoretical grasp on major mental events, giving us a better understanding of individual minds, and fostering a more integrated therapeutic intervention. The intended readers include neuroscientists, psychiatrists, psychologists, and anyone interested in the human mind. Describes a model integrating biological neuroscience principles, subjective psychological science, and nonlinear physics and mathematics Offers a wide-ranging, holistic exploration of the mind and its conscious and unconscious realms, using myth, art, philosophy, neurobiology and basic sciences Introduces the future new paradigm for emergent science, the Poem, to replace the outdated classical reductionistic paradigm of the Machine.
    Materialart: Online-Ressource
    Seiten: XXII, 167 p. 25 illus., 6 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2022.
    ISBN: 9783030864156
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 35
    Schlagwort(e): Neurosciences. ; Proteins. ; Nervous system Diseases. ; Genetics. ; Neuroscience. ; Proteins. ; Neurological Disorders. ; Genetics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Proteins Commonly Linked to Autism Spectrum Disorder -- Chapter 2. Protein Aggregation and Recycling -- Chapter 3. Neuron Membrane and Trafficking Protein Kinases (PKA&B) involved in ASD -- Chapter 4. Proteomic profiling in children with ASD -- Chapter 5. Molecular Protein biomarkers for developing diagnostics and therapeutic interventions.Gene Regulation in Autism. OR Neurodevelopmental Epigenomics -- Chapter 6. Chromatin and Epigenetic Regulation in ASD -- Chapter 7. Autism and the Scaffolding Protein Neurobeachin -- Chapter 8. Genomic Profiling in ADHD subjects -- Chapter 9. ADHD and Epigenetics Regulation -- Chapter 10. Proteomic Approach in ADHD -- Chapter 11. DHD and the Dopamine Transporter (DAT) -- Chapter 12. Protein Kinases involved in ADHD -- Chapter 13. ADHD and Cell Adhesion Molecule 1 – CAM 1 (CADM1 gene) -- Chapter 14. ASD and Cell Adhesion Molecule Astrotactin -- Chapter 15. Possible therapeutic interventions through proteins in ADHD.
    Kurzfassung: This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.
    Materialart: Online-Ressource
    Seiten: XV, 339 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811597817
    Serie: Nutritional Neurosciences,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 36
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neurology . ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry. ; Neuroscience. ; Neurology. ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Treatments Against Glutamatergic Excitotoxicity in Ischemic Stroke -- Definitions and Concepts of Stress -- Role of Glutamatergic Neurotransmission in the Pathophysiology of Stress-Related Disorders and Chronic Stress Response -- Current Glutamatergic Treatments and Future Directions for Glutamate-Based Management of Chronic Stress and Stress-Related Disorders -- The Role of the Glutamate System in Posttraumatic Stress Disorder and Glutamate-Based Treatments -- Glutamate in Migraine Neurobiology and Treatment -- Astrocyte Glutamate Transporter EAAT2 in Alzheimer Dementia -- The Glutamatergic System as a Target for the Development of New Pharmacological Treatments of Bipolar Disorder -- CNS Glutamate in Impulsive Aggression -- Glutamatergic Treatments for Parkinsons' Disease -- The Modulation of Glutamatergic Signaling as a Potential Therapeutic Strategy for Major Depression -- Glutamate-Based Treatment for Amyotrophic Lateral Sclerosis/Motor Neuron Disease -- Modulation of Glutamate for Chronic Pain Management -- Pharmacological Role of Glutamate Transporters in Substance Use Disorders -- Glutamate in Multiple Sclerosis: From Pathophysiology to Treatments -- The Role of Glutamate Dysregulation in the Etiology of ADHD -- Glutamate, Glutamatergic Drugs and Schizophrenia -- Glutamate and Epilepsy: An Insight from Temporal Lobe Epilepsy -- Glutamate Function in Anxiety Disorders and OCD: Evidence from Clinical and Translational Studies -- Modulators of Glutamatergic Signaling as Potential Treatments for Autism Spectrum Disorders.
    Kurzfassung: This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.
    Materialart: Online-Ressource
    Seiten: XXXV, 600 p. 43 illus., 40 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030874803
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 37
    Schlagwort(e): Neurosciences. ; Neural circuitry. ; Bioinformatics. ; Computer science. ; Neuroscience. ; Neural Circuits. ; Computational and Systems Biology. ; Computer Science.
    Beschreibung / Inhaltsverzeichnis: PART I. Cellular Scale -- Chapter 1. Modelling Neurons in 3D at the Nanoscale -- Chapter 2. Modelling Dendrites and Spatially-Distributed Neuronal Membrane Properties -- Chapter 3. A User's Guide to Generalized Integrate-and-Fire Models -- Chapter 4. Neuron-glia Interactions and Brain Circuits -- Chapter 5. Short-term Synaptic Plasticity: Microscopic Modelling and (some) Computational Implications -- PART II. Molecular Scale -- Chapter 6. The Mean Field Approach for Populations of Spiking Neurons -- Chapter 7. Multidimensional Dynamical Systems with Noise -- Chapter 8. Computing Extracellular Electric Potentials from Neuronal Simulations -- Chapter 9. Bringing Anatomical Information into Neuronal Network Models -- PART III. Network Scale -- Chapter 10. Computational Concepts for Reconstructing and Simulating Brain Tissue -- Chapter 11. Reconstruction of the Hippocampus -- Chapter 12. Challenges for Place and Grid Cell Models -- Chapter 13. Whole-Brain Modelling: Past, Present, and Future.
    Kurzfassung: This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. .
    Materialart: Online-Ressource
    Seiten: XII, 359 p. 115 illus., 94 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030894399
    Serie: Cellular Neuroscience, Neural Circuits and Systems Neuroscience, 1359
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 38
    Online-Ressource
    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Establishing the molecular and functional diversity of spinal motoneurons -- Chloride homeostasis in developing motoneurons -- Normal development and pathology of motoneurons: anatomy, electrophysiological properties, firing patterns and circuit connectivity -- Homeostatic regulation of motoneuron properties in development -- Homeostatic plasticity of the mammalian neuromuscular junction -- Diversity of mammalian motoneurons and motor units -- Synaptic projections of motoneurons within the spinal cord -- Recruitment of motoneurons -- Electrical properties of adult mammalian motoneurons.-The cellular basis for the generation of firing patterns in human motor units -- Motoneuronal regulation of central pattern generator and network function -- Extraocular motoneurons and neurotrophism -- Motoneuron diseases -- Electrical and morphological properties of developing motoneurons in postnatal mice and early abnormalities in sod1 transgenic mice -- From physiological properties to selective vulnerability of motor units in amyotrophic lateral sclerosis. .
    Kurzfassung: This book aims to provide a comprehensive and timely review of new findings in motoneuron research. Recent findings have revealed that motoneurons are more complex and have more extensive functions than previously imagined. Some of the molecular and genetic pathways that orchestrate the development of motoneurons have been discovered, as have the mechanisms responsible for the selective innervation of muscles by specific pools of motoneurons. These novel findings are revolutionizing ideas about the function of motoneurons and have important implications for motoneuron disease. Chapters from several of the foremost figures in the field are included in this book and will emphasize how basic science is the engine driving the discovery of novel treatments for degenerative motoneuron diseases. Cutting edge developments in the use of pluripotent stem cells to correct motoneuron disease will be also be covered. This book would be useful to students of basic motoneuron physiology, locomotor behavior and motor control. This book would also be of interest to professional neuroscientists, neurologists, and neurosurgeons.
    Materialart: Online-Ressource
    Seiten: XII, 400 p. 81 illus., 64 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031071676
    Serie: Advances in Neurobiology, 28
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 39
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Cognitive psychology. ; Nutrition   . ; Neuropsychology. ; Neuroscience. ; Cognitive Psychology. ; Nutrition. ; Neuropsychology.
    Beschreibung / Inhaltsverzeichnis: SECTION I Food, Brain function, and Behavior- Chapter 1: Food and brain development (Ramya Nadig) -- Chapter 2: Nutrition and brain functions in Health and Disease (Heba Mansour) -- Chapter 3: Nutrition, cognitive functions, and emotions (Rasoul Ghasemi) -- Chapter 4: Ketogenic diet: Implications for treatment and injury in neuropsychiatry and motor functioning (fatima dakroub) -- Chapter 5: Effects of malnutrition on brain development (Pranshul Sethi) -- Chapter 6: Nutrition, neurotransmitters, and behavior (Sumit Srivastav) -- Chapter 7: OMICS in Schizophrenia and Alzheimer’s Disease (Sumit Srivastav) -- SECTION II Psychiatric disorders related to nutrition: deficiency or overload -- Chapter 8: Effects of Depression and Antidepressant Therapy on Serum Zinc Levels (Samer El Hayek) -- Chapter 9: Nutrition and Depression (Ramdas Ransing) -- Chapter 10: Nutritional Deficiencies in Obsessive-Compulsive Disorder and Possible Treatment Interventions (Samer El Hayek) -- Chapter 11: Caffeine, Mental wellbeing, and Psychiatric Disorders (Ahmed Radwan) -- Chapter 12: Biopsychology of chocolate craving (Laura Orsolini) -- Chapter13: Food addiction (Samer El Hayek) -- Chapter 14: Nutrition and Anxiety disorders (Ramli Musa) -- Chapter 15: Nutrition and substance use disorder (Zehra Batool) -- Chapter 16: Nutrition and Psychiatric Disorders: Focus on Schizophrenia (Heba Mansour) -- Chapter 17: High fat diet and psychiatric disorders: what is the interplay? (Pranshul Sethi).
    Kurzfassung: The book comprehensively reviews the role of nutrition in psychiatric disorders. It provides mechanistic insights into the effects of nutrition on metabolic pathways, mitochondrial nutrients, neurodegeneration and CNS disorders, cell signaling, and neuronal functions. The book further highlights the role of diet in preventing and treating mental health and modifying drug treatment effects. Further, it explores the relationship between nutrition and psychiatric disorders, including depression, autism, anxiety, Attention-Deficit / Hyperactivity Disorder, and OCD. The book further explores the recent advancements in understanding the important role of nutrients as therapeutics in various psychiatric disorders. Lastly, it presents an overview of nutrients as neuroprotective agents along with the main principles of nutrigenomics. The book is essential reading for neuroscientists interested interest in food therapeutic strategies.
    Materialart: Online-Ressource
    Seiten: XVIII, 383 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811950216
    Serie: Nutritional Neurosciences,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 40
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    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neuropsychology. ; Psychology, Pathological. ; Therapeutics. ; Pharmacology. ; Psychology. ; Neuroscience. ; Neuropsychology. ; Psychopathology. ; Therapeutics. ; Pharmacology. ; Behavioral Sciences and Psychology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Epidemiology of Binge Eating -- Chapter 2. Binge Eating Assessement -- Chapter 3. Developmental and Cultural Aspects of Binge Eating -- Chapter 4. Psychosocial Correlates of Binge Eating -- Chapter 5. Weight Dysregulation, Positive Energy Balance and Binge Eating in Eating Disorders -- Chapter 6. Theoretical Development and Maintenance Models of Binge Eating -- Chapter 7. Preclinical Models of Stress and Environmental Influences on Binge Eating -- Chapter 8. Emerging Translational Treatments to Target the Neural Networks of Binge Eating -- Chapter 9. Neuroimaging to Study Brain Reward Processing and Reward-Based Learning in Binge Eating Pathology -- Chapter 10. The Neurobiological Basis of Executive Function Alterations in Binge Eating Populations -- Chapter 11. Influence of Genetics and Sex Hormones on Binge Eating -- Chapter 12. Neuroendocrine Correlates of Binge Eating -- Chapter 13. Body Image Disturbance and Binge Eating -- Chapter 14. Food Addiction, Binge Eating and the Role of Dietary Restraint: Converging Evidence from Animal and Human Studies -- Chapter 15. Prevention of Binge Eating -- Chapter 16. Medication for Binge Eating -- Chapter 17. Oxytocin: Potential New Treatment for Binge Eating -- Chapter 18. Psychotherapy for Binge Eating -- Chapter 19. Self Help Interventions for the Treatment of Binge Eating -- Chapter 20. New Avenues for the Treatment of Binge Eating based on Implicit Processes -- Chapter 21. Binge-Eating Disorder: Unanswered Questions -- Chapter 22. Overcoming Barriers to the Treatment of Binge Eating.
    Kurzfassung: This book provides a comprehensive overview of our current understanding of binge eating, which is characterized by the uncontrollable consumption of large amounts of food in a discrete time period. Written by experts on eating disorders, it first introduces the phenotype of binge eating, including its epidemiology and assessment. It then describes the underlying neurobiological alterations, drawing on cutting-edge animal models and human studies to do so. In addition, it extensively discusses current treatment models, including medication, psychotherapy, self-interventions and disease prevention. Lastly, an outlook on the future research agenda rounds out the coverage. Given binge eating’s current status as an under-researched symptom, but one shared across many eating disorders, this book provides an up-to-date, integrative and comprehensive synthesis of recent research and offers a valuable reference for scientists and clinicians alike.
    Materialart: Online-Ressource
    Seiten: X, 321 p. 14 illus., 11 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030435622
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 41
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    Singapore :Springer Nature Singapore :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Developmental psychology. ; Linguistics. ; Physical anthropology. ; Behavioral Neuroscience. ; Child and Adolescence Psychology. ; Linguistics. ; Physical-Biological Anthropology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Evidence for the gestural origins of language that is not incompatible with the vocal theory of language origins -- Chapter 2. Primate Voice Physiology: Similarities and Difference between Humans and Non-Human Primates -- Chapter 3. Integrations of multiple abilities underlying the evolution of primate vocalizations -- Chapter 4. Conversational rules among primate species -- Chapter 5. Language evolution from a perspective of Broca’s area -- Chapter 6. Social scaffolding of the development of vocal communication and language during infancy -- Chapter 7. Emergence of the distinction between "verbal" and "musical" skills in early childhood development -- Chapter 8. Yakut tradition of "Talking Jew's Harp" and its relation to vowel harmony as a paradigm of formative influence of music on language -- Chapter 9. Were musicians and artists in the Ice Age caves likely with autism spectrum disorder? - A neurodiversity hypothesis to explain the co-emergence of art and music as a type of prosodic protolanguage.
    Kurzfassung: This book summarizes the latest research on the origins of language, with a focus on the process of evolution and differentiation of language. It provides an update on the earlier successful book, “The Origins of Language” edited by Nobuo Masataka and published in 2008, with new content on emerging topics. Drawing on the empirical evidence in each respective chapter, the editor presents a coherent account of how language evolved, how music differentiated from language, and how humans finally became neurodivergent as a species. Chapters on nonhuman primate communication reveal that the evolution of language required the neural rewiring of circuits that controlled vocalization. Language contributed not only to the differentiation of our conceptual ability but also to the differentiation of psychic functions of concepts, emotion, and behavior. It is noteworthy that a rudimentary form of syntax (regularity of call sequences) has emerged in nonhuman primates. The following chapters explain how music differentiated from language, whereas the pre-linguistic system, or the “prosodic protolanguage,” in nonhuman primates provided a precursor for both language and music. Readers will gain a new understanding of music as a rudimentary form of language that has been discarded in the course of evolution and its role in restoring the primordial synthesis in the human psyche. The discussion leads to an inspiring insight into autism and neurodiversity in humans. This thought-provoking and carefully presented book will appeal to a wide range of readers in linguistics, psychology, phonology, biology, anthropology and music.
    Materialart: Online-Ressource
    Seiten: IX, 345 p. 29 illus., 19 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811542503
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 42
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Anatomy. ; Internal medicine. ; Neuroscience. ; Anatomy. ; Internal Medicine.
    Beschreibung / Inhaltsverzeichnis: Part I. Molecular Specification of Hypothalamic/Pituitary Cells -- Development of the Neuroendocrine Hypothalamus -- Sonic hedgehog in Hypothalamus Development -- Development of the Hypothalamus in Xenopus laevis -- Gene Regulatory Programs in the Development of Hypothalamic Arcuate Nucleus Neurons -- Winding the Clock: Development of Hypothalamic Structures Controlling Biological Timing and Sleep -- Pituitary Development and Organogenesis: Transcription Factors in Development and Disease -- Part II. Developmental Modulators and Epigenetic Factors -- Hypothalamic Development: Role of GABA -- Epigenetic and Transcriptional Regulation of the Reproductive Hypothalamus -- Epigenetic Regulation of the GnRH and Kiss1 Genes: Developmental Perspectives -- Imprinted Genes and Hypothalamic Function -- Rhythmic Epigenetics in Neuroendocrine and Immune Systems -- Part III. Development of Neuroendocrine Circuits -- Development of Limbic System Stress-Threat Circuitry -- Organization and Postnatal Development of Visceral Sensory Inputs to the Neuroendocrine Hypothalamus -- Astrocytes and Development of Neuroendocrine Circuits -- Origins of Sex Differentiation of Brain and Behavior -- Development and Modulation of Female Reproductive Function by Circadian Signals.
    Kurzfassung: In this book, experts in the field discuss the latest research in developmental neuroendocrinology. Given that the hypothalamus is the center of neuroendocrine activity, the reader will learn about the molecular specification of hypothalamic cells, developmental modulators and epigenetic factors influencing hypothalamic development, and the development of neuroendocrine circuits. Each chapter provides a concise review of the current and future perspectives in developmental neuroendocrinology. Important insights into state-of-the-art techniques applied to functional circuit tracking, lineage tracing of hypothalamic cells, and the identification of genes altered through epigenetic mechanisms are also provided. Given its scope, the book will appeal to all students and researchers who are eager to understand the processes involved in hypothalamus development and the establishment of neuroendocrine circuits. This is the ninth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series* that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. *Volumes 1-7 published by Wiley.
    Materialart: Online-Ressource
    Seiten: X, 468 p. 85 illus., 77 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030400026
    Serie: Masterclass in Neuroendocrinology, 9
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 43
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neurophysiology. ; Gastroenterology. ; Neuroscience. ; Neurophysiology. ; Gastroenterology.
    Beschreibung / Inhaltsverzeichnis: Luminal Chemoreceptors and Intrinsic Nerves -- Key Modulators of Digestive Motor Function -- Comparative and evolutionary aspects of the ENS -- Exploring synaptic transmission in the ENS: electrophysiology, functional studies and modelling -- Mucosal Serotonin5 -- Ca2+ signaling in Interstitial cells of Cajal: The mechanistic basis for many GI motility behaviors -- Identifying types of neurons in the enteric nervous systes -- Clinico-Pathological Features of severe gut dysmotility -- Purinergic signaling in the ENS -- Myogenic and neural control in concert -- colonic response to physiological and chemical stimuli -- Molecular targets to alleviate enteric neuropathy and gastrointestinal dysfunction -- The emerging role of the gut-brain microbiota axis in neurodevelopmental disorders -- A view on how enteric neurons monitor luminal content -- Interaction of the microbiota and the developing ENS -- Influence of the circadian rhythm on enteric nervous system function -- Mechanosensitive Enteric Neurons (MEN) at work -- Neurogenetic investigation of the ENS and gut motility -- The shaggy dog story of enteric signaling: serotonin, a molecular megillah -- Contribution of enteric neuroglial remodelling to inflammatory bowel disease and cancer evolution -- Examining cellular metabolism in the enteric nervous system -- Embryonic development of motility: a bottom-up approach to the workings of the intestine -- Quantitative analysis of intestinal movements with spatiotemporal maps -- The roles of Mas related G-protein coupled receptors in the gut -- Refining Enteric Neural Circuitry by Quantitative Morphology, Transcriptomics and Function in Mice” -- Extrinsic modulation of enteric circuits that regulate colon function in health and disease -- Activating and Modeling ENS Circuits in Mouse Colon -- Neurons, macrophages and glia: the role of intercellular communication for gut motility -- Modelling development of the ENS: What's been done and what's next -- Epithelial 5-HT4 receptors as a target for treating constipation and colitis -- Activity in Enteric Neural circuits underlying propulsion -- Contribution of the ENS to autoimmune diseases and irritable bowel syndrome.
    Kurzfassung: This book is based on the proceedings of the Enteric Nervous System conference in Adelaide, Australia, as part of the International Federation for Neurogastroenterology and Motility. The book focuses on methodologic strategies and unresolved issues in the field and explores where the future is heading and what technological advances have been made to address current and future questions. The Enteric Nervous System II continues in the tradition of a popular earlier volume which covered the previous meeting. Many of the same authors are contributing to this new volume, presenting state-of-the-art updates on the many developments in the field since the earlier meeting. The coverage include a wide range of topics, from structure and function of the enteric nervous system through gut motility and visceral pain. The author team includes long-established authorities who significantly contributed to the advances in ENS research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field. .
    Materialart: Online-Ressource
    Seiten: XI, 337 p. 65 illus., 61 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031058431
    Serie: Advances in Experimental Medicine and Biology, 1383
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 44
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    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Neuropsychology. ; Neuroscience. ; Neuropsychology.
    Beschreibung / Inhaltsverzeichnis: Part 1. Brain network concepts -- Chapter 1. Task MRI-based functional brain network of anxiety -- Chapter 2. Phenotype network and brain structural covariance network of anxiety -- Chapter 3. linear/nonlinear micro-and-macro state EEG-based functional networks for anxiety -- Chapter 4. White matter-based structural brain network of anxiety -- Chapter 5. Resting state abnormalities in anxiety disorders and spatiotemporal psychopathology -- Part 2. Neurobiological Aspects -- Chapter 6. Gene-environmental interactions and role of epigenetics in anxiety disorders -- Chapter 7. The role of the oxytocin system in anxiety disorders -- Chapter 8. Translational studies in the complex roles of neurotransmitter systems in anxiety and anxiety disorders -- Chapter 9. The role of early life stress in HPA axis dysfunction in anxiety disorders -- Chapter 10. Immune-kynurenine pathways and the gut-microbiota-brain axis in anxiety disorders -- Chapter 11. Experimental anxiety model for anxiety disorders: relevance to drug discovery -- Part 3. Diagnostic and clinical Issues -- Chapter 12. Anxiety disorders in DSM-5: changes, controversies, and future directions -- Chapter 13. Biological markers to differentiate the type of anxiety disorders -- Chapter 14. Comorbid anxiety and depression: clinical and conceptual consideration, transdiagnostic treatment -- Chapter 15. Anxiety disorders and medical comorbidity: treatment implications -- Part 4. Therapeutic Issues -- Chapter 16. Biofeedback and Neurofeedback for Anxiety Disorders: A Quantitative and Qualitative Systematic Review -- Chapter 17. Cognitive Behavioral Therapy, Mindfulness-Based Cognitive Therapy and Acceptance Commitment Therapy for Anxiety Disorders: Integrating Traditional with Digital Treatment Approaches -- Chapter 18. Neurostimulation in anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder -- Chapter 19. Current and novel psychopharmacological drugs for anxiety disorders -- Chapter 20. Role of benzodiazepines in anxiety disorders -- Chapter 21. Virtual Reality for Anxiety Disorders: Rethinking a Field in Expansion -- Chapter 22. Current research on complementary and alternative medicine (CAM) in the treatments of anxiety disorders: evidence based review -- Chapter 23. Contemporary Psychodynamic Approaches to Treating Anxiety: Theory, Research, and Practice -- Chapter 24. Well-being therapy in anxiety disorders -- Part 5. Anxiety and precision psychiatry -- Chapter 25. Personalized clinical approaches to anxiety disorders -- Chapter 26. The role of hormonal and reproductive status in the treatment of anxiety disorders in women -- Chapter 27. Risk factors and prevention strategies for anxiety disorders in childhood and adolescence -- Chapter 28. Anxiety disorders in the elderly.
    Kurzfassung: This book reviews all important aspects of anxiety disorders with the aim of shedding new light on these disorders through combined understanding of traditional and novel paradigms. The book is divided into five sections, the first of which reinterprets anxiety from a network science perspective, examining the altered topological properties of brain networks in anxiety disorders. The second section discusses recent advances in understanding of the neurobiology of anxiety disorders, covering, for example, gene-environmental interactions and the roles of neurotransmitter systems and the oxytocin system. A wide range of diagnostic and clinical issues in anxiety disorders are then addressed, before turning attention to contemporary treatment approaches in the context of novel bio-psychosocial-behavioral models, including bio- and neurofeedback, cognitive behavioral therapy, neurostimulation, virtual reality exposure therapy, pharmacological interventions, psychodynamic therapy, and CAM options. The final section is devoted to precision psychiatry in anxiety disorders, an increasingly important area as we move toward personalized treatment. Anxiety Disorders will be of interest for all researchers and clinicians in the field.
    Materialart: Online-Ressource
    Seiten: VII, 576 p. 32 illus., 25 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789813297050
    Serie: Advances in Experimental Medicine and Biology, 1191
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 45
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Bioenergetics. ; Biomedical engineering. ; Neurochemistry. ; Mental health. ; Neuroscience. ; Bioenergetics. ; Biomedical Engineering and Bioengineering. ; Neurochemistry. ; Mental Health.
    Beschreibung / Inhaltsverzeichnis: Aim of the book -- Basic principles and technology of nadh and multiparametric monitoring used in studying cortical spreading depression (csd) -- Single point and multisite monitoring of brain nadh fluorescence under csd -- Sequence of physiological responses recorded during induced csd event -- Spontaneous development of csd related to brain pathophysiological conditions -- The effects of brain metabolic and other perturbations on the responses to induced csd -- Effects of pharmacological agents on csd -- Clinical monitoring of csd in the human brain -- CSD and the lifenlight score (lls) -- Discussion and conclusions -- Index.
    Kurzfassung: This book focuses on energy metabolism and brain functions related to Cortical Spreading Depression of Leao (CSD), an important issue in brain pathophysiology. The first part of the book offers a comprehensive overview of the history and early research on CSD, and then discusses the recent advances in the technology used to map and monitor brain mitochondrial NADH redox state and other physiological functions during CSD. The chapters explore the connection between CSD and mitochondrial function under hypoxia, Ischemia and various drugs treatment, and provide a resource to scientists researching the development of CSD during various brain pathophysiological conditions. This book is essential to scientists and students working in the field of bioenergetics of the brain and various organs and tissues in the body. The use of this technology is also crucial and applicable in the neuroscience field.
    Materialart: Online-Ressource
    Seiten: XXI, 420 p. 242 illus., 58 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031080685
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 46
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    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Evolution (Biology). ; Acoustics. ; Vertebrates. ; Coding theory. ; Information theory. ; Communication. ; Behavioral Neuroscience. ; Evolutionary Biology. ; Acoustics. ; Vertebrate Zoology. ; Coding and Information Theory. ; Media and Communication.
    Beschreibung / Inhaltsverzeichnis: Acoustic Coding Strategies Through the Lens of the Mathematical Theory of Communication -- To Shout or to Whisper? Strategies for Encoding Public and Private Information in Sound Signals -- The Bird Dawn Chorus Revisited -- Coding Human Languages for Long-Range Communication in Natural Ecological Environments: Shouting, Whistling, and Drumming -- Coding of Static Information in Terrestrial Mammal Vocal Signals -- Coding for ‘Dynamic’ Information: Vocal Expression of Emotional Arousal and Valence in Non-human Animals -- Seasonal Hormone Fluctuations and Song Structure of Birds -- From Vocal to Neural Encoding: A Transversal Investigation of Information Transmission at Long Distance in Birds -- Mother–Offspring Vocal Recognition and Social System in Pinnipeds -- Acoustic Coding of Information in a Complex Social Network: Identity Signaling in Northern Elephant Seals -- How Songbird Females Sample Male Song: Communication Networks and Mate Choice -- Interspecific Communication: Gaining Information from Heterospecific Alarm Calls -- A Framework to Understand Interspecific Multimodal Signaling Systems.
    Kurzfassung: Information is a core concept in animal communication: individuals routinely produce, acquire, process and store information, which provides the basis for their social life. This book focuses on how animal acoustic signals code information and how this coding can be shaped by various environmental and social constraints. Taking birds and mammals, including humans, as models, the authors explore such topics as communication strategies for “public” and “private” signaling, static and dynamic signaling, the diversity of coded information and the way information is decoded by the receiver. The book appeals to a wide audience, ranging from bioacousticians, ethologists and ecologists to evolutionary biologists. Intended for students and researchers alike, it promotes the idea that Shannon and Weaver’s Mathematical Theory of Communication still represents a strong framework for understanding all aspects of the communication process, including its dynamic dimensions.
    Materialart: Online-Ressource
    Seiten: X, 325 p. 55 illus., 35 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030392000
    Serie: Animal Signals and Communication, 7
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 47
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: A Review of the Cholinergic System and Therapeutic Approaches to Treat Brain Disorders -- Acetylcholine and Spontaneous Recognition Memory in Rodents and Primates -- Endogenous Acetylcholine and Its Modulation of Cortical Microcircuits to Enhance Cognition -- Cholinergic Signaling Dynamics and Cognitive Control of Attention -- Involvement of Nicotinic Receptors in Working Memory Function -- Nicotinic Receptors Underlying Nicotine Dependence: Evidence fromTransgenic Mouse Models -- Cholinergic Receptors and Addiction -- Behavioral and Molecular Basis of Cholinergic Modulation of Pain: Focus on Nicotinic Acetylcholine Receptors -- An Evolving Therapeutic Rationale for Targeting the α7 Nicotinic Acetylcholine Receptor in Autism Spectrum Disorder -- Activators of α7 nAChR as Potential Therapeutics for Cognitive Impairment.
    Kurzfassung: The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.
    Materialart: Online-Ressource
    Seiten: X, 245 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030560133
    Serie: Current Topics in Behavioral Neurosciences, 45
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 48
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    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Beschreibung / Inhaltsverzeichnis: Scaling the Levels of Birdsong Analysis -- Neural Circuits Underlying Vocal Learning in Songbirds -- New Insights into the Avian Song System and Neuronal Control of Learned Vocalizations -- The Song Circuit as a Model of Basal Ganglia Function -- Integrating Form and Function in the Songbird Auditory Forebrain -- Hormonal Regulation of Avian Auditory Processing -- The Neuroethology of Vocal Communication in Songbirds: Production and Perception of a Call Repertoire -- Linking Features of Genomic Function to Fundamental Features of Learned Vocal Communication -- Vocal Performance in Songbirds: From Mechanisms to Evolution.
    Kurzfassung: This volume provides comprehensive, integrative, and comparative perspectives on birdsong and underscores the importance of birdsong research to behavioral and systems neuroscience, evolutionary biology, and biomedical research. Scaling the Levels of Birdsong Analysis Jon T. Sakata and Sarah C. Woolley Neural Circuits Underlying Vocal Learning in Songbirds Jon T. Sakata and Yoko Yazaki-Sugiyama New Insights into the Avian Song System and Neuronal Control of Learned Vocalizations Karagh Murphy, Koedi S. Lawley, Perry Smith, and Jonathan F. Prather The Song Circuit as a Model of Basal Ganglia Function Arthur Leblois and David J. Perkel Integrating Form and Function in the Songbird Auditory Forebrain Sarah C. Woolley and Sarah M. N. Woolley Hormonal Regulation of Avian Auditory Processing Luke Remage-Healey The Neuroethology of Vocal Communication in Songbirds: Production and Perception of a Call Repertoire Julie E. Elie and Frédéric E. Theunissen Linking Features of Genomic Function to Fundamental Features of Learned Vocal Communication Sarah E. London Vocal Performance in Songbirds: From Mechanisms to Evolution Jeffrey Podos and HaCheol Sung.
    Materialart: Online-Ressource
    Seiten: XVIII, 268 p. 37 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030346836
    Serie: Springer Handbook of Auditory Research, 71
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 49
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    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Human physiology. ; Zoology. ; Neuropsychology. ; Neuroscience. ; Human Physiology. ; Zoology. ; Neuropsychology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Dorsolateral prefrontal cortex -- Chapter 2. Historical perspective of prefrontal research -- Chapter 3. Working memory and prefrontal functions -- Chapter 4. Executive control -- Chapter 5. Sensory and Motor Processing -- Chapter 6. Cognitive control -- Chapter 7. Decision-making -- Chapter 8. Metacognition -- Chapter 9. Top-down control -- Chapter 10. Prefrontal cortex and working memory.
    Kurzfassung: The prefrontal cortex is known to play important roles for performing a variety of higher cognitive functions. Among regions of the prefrontal cortex, the dorsolateral prefrontal cortex plays the most important roles for these functions. This book focuses on functions of the dorsolateral prefrontal cortex, summarizes research results obtained mainly by non-human primate studies, and describes neural mechanisms of executive functions that the dorsolateral prefrontal cortex participates. First, to understand the feature of the dorsolateral prefrontal cortex and how its function has been understood, anatomical and functional features of the dorsolateral prefrontal cortex and historical overview of prefrontal functions are described. To understand functions of the prefrontal cortex and neural mechanisms of executive functions, working memory is an important concept and sustained activation during the memory period of working memory tasks is known as a neural mechanism of working memory. Therefore, this book describes features of sustained memory-related activity based on neurophysiological results obtained in the prefrontal cortex and how memory-related activity contributes to executive functions including control of attention, inhibitory control, task management, and planning. And further, this book describes how the dorsolateral prefrontal cortex contributes to neural mechanisms for sensory and motor processing, memory control in multi-task performance, decision-making, metacognition, and top-down control. Thus, this book provides important information regarding neural mechanisms of dorsolateral prefrontal functions to neuroscientists and helps to plan further investigation to understand prefrontal functions in primates and human subjects.
    Materialart: Online-Ressource
    Seiten: XVIII, 543 p. 148 illus., 70 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811972683
    Serie: Brain Science,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 50
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Proteins. ; Cytology. ; Neuroscience. ; Proteins. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Preface -- Calcium signaling: from basics to bedside -- Measuring Ca2+ in living cells -- High-throughput fluorescence assays for Ion Channels and GPCRs -- Imaging Native Calcium Currents in Brain Slices -- Molecular diversity of plasma membrane Ca2+ transporting ATPases: their function under normal and pathological conditions -- A role for SERCA pumps in the neurobiology of neuropsychiatric and neurodegenerative disorders -- Cytoplasmic Calcium Buffering: An Integrative Crosstalk -- An update on calcium binding proteins -- Manuel Campos‐Toimil -- New insights in the IP3 receptor and its regulation -- Expression of the inositol 1,4,5-trisphosphate receptor and the ryanodine receptor Ca2+-release channels in the beta-cells and alpha- cells of the human islets of Langerhans -- Evolution of Excitation-Contraction Coupling -- Molecular Insights into Calcium Dependent Regulation of Ryanodine Receptor Calcium Release Channels -- Sarco-endoplasmic reticulum calcium release model based on changes in the luminal calcium content visualized from the luminal side -- Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores -- Calcium Signaling in the Heart -- Molecular basis and regulation of store-operated calcium entry -- Structure and activation mechanisms of CRAC channels -- Canonical Transient Potential Receptor-3 Channels in Normal and Diseased Airway Smooth Muscle Cells -- Pathophysiological significance of store-operated calcium entry in cardiovascular and skeletal muscle disorders and angiogenesis -- Calcium signalling and the regulation of chemosensitivity in cancer cells: role of the Transient Receptor Potential channels -- Targeting Transient Receptor Potential Channels by microRNAs drives tumor development and progression -- Calcium channels and Calcium-regulated channels in human red blood cells -- Regulation of multifunctional calcium/calmodulin stimulated protein kinases by molecular targeting -- Widespread roles of CaMK-II in Developmental Pathways -- Readily releasable stores of calcium in neuronal endolysosomes: Physiological and pathophysiological relevance -- At the crossing of ER stress and MAMs: A key role of Sigma-1 receptor?- ER-mitochondria calcium transfer, organelle contacts and neurodegenerative diseases -- The Role of Mitochondrial Calcium Signaling in the Pathophysiology of Cancer Cells -- Calcium Signaling and Gene Expression -- Simulation Strategies for Calcium Microdomains and Calcium Noise -- A statistical view on calcium oscillations -- Calcium Regulation of Bacterial Virulence -- Ca2+ Signaling in Drosophila Photoreceptor Cells -- Calcium imaging in Drosophila melanogaster -- Calcium imaging in the zebrafish -- Stimulation-secretion coupling in the beta cells: from basic to bedside -- Calcium dynamics and synaptic plasticity -- Calcium signaling during brain aging and its influence on the hippocampal synaptic plasticity -- Calcium Signaling in Endothelial Colony Forming Cells in Health and Disease -- Sensing Extracellular Calcium - An Insight into the Structure and Function of the Calcium-Sensing Receptor (CaSR) -- Extracellular Ca2+ in bone marrow -- Calcium in Cell-Extracellular Matrix Interactions -- Index.
    Kurzfassung: This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Materialart: Online-Ressource
    Seiten: XIII, 1110 p. 150 illus., 132 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2020.
    ISBN: 9783030124571
    Serie: Advances in Experimental Medicine and Biology, 1131
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 51
    Online-Ressource
    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Human physiology. ; Neurology . ; Neuroscience. ; Human Physiology. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Neurophysiology of Heart -- Chapter 2. Physiology of Cardiovascular System -- Chapter 3. THE Brain-Heart Crosstalk. .
    Kurzfassung: This book discusses the underlying mechanisms connecting the brain and heart. The physiology of the brain is such that it is easily affected by any altered physiology of other systems, which in turn may compromise cerebral blood flow and oxygenation. Together, the brain and heart control our body systems, allowing them to function automatically. This interaction between the brain and other systems makes it important for us to understand how any kind of injury to the brain can produce complications in remote organs or systems, such as the heart. The central nervous system is responsible for vegetative function and is central to homeostasis. Further, central nervous system responses are linked to the ongoing function of other organ systems e.g. feeding, thermoregulation, reproduction and muscle activity. It is therefore logical that neural control of the cardiovascular system must also interact with the neural control of other organ systems. This book explains in detail stressed cardiac conditions, discussing the pathophysiology and proposed treatment, and also describing lesser-known crosstalks between the acutely or chronically affected brain and heart. .
    Materialart: Online-Ressource
    Seiten: XIII, 130 p. 35 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811524974
    Serie: Physiology in Clinical Neurosciences – Brain and Spinal Cord Crosstalks,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 52
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    Online-Ressource
    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Medicine Research. ; Biology Research. ; Proteins . ; Biology Technique. ; Neuroscience. ; Biomedical Research. ; Protein Biochemistry. ; Biological Techniques.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Peroxisome: metabolic functions and biogenesis -- Chapter 2. Peroxisomal Dysfunction and Oxidative Stress in Neurodegenerative Disease: A Bidirectional Crosstalk -- Chapter 3. 7-hydroxycholesterols-induced peroxisomal disorders in glial and microglial cells: potential role in neurodegeneration -- Chapter 4. Peroxisome biogenesis disorders -- Chapter 5. Fatty Acid Oxidation in Peroxisomes: Enzymology, Metabolic Crosstalk with Other Organelles And Peroxisomal Disorders -- Chapter 6. Zellweger syndrome disorders: from severe neonatal disease to atypical adult presentation -- Chapter 7. Heimler Syndrome -- Chapter 8. Potential involvement of peroxisome in multiple sclerosis and Alzheimer’s disease -- Chapter 9. Developmental and degenerative cerebellar pathologies in peroxisomal β-oxidation deficiency -- Chapter 10. A mouse model system to study peroxisomal role in neurodegenerative diseases such as peroxisome biogenesis disorders -- Chapter 11. The Drosophila melanogaster as genetic model system to dissect the mechanisms of disease that lead to neurodegeneration in adrenoleukodystrophy -- Chapter 12. Human peroxisomal 3-keto-acyl-CoA thiolase: tissue expression and metabolic regulation -- Chapter 13. Biological functions of plasmalogens -- Chapter 14. Therapeutic efficacy of plasmalogens for Alzheimer’s disease, Mild Cognitive Impairment and Parkinson’s disease in conjunction with a new hypothesis for the etiology of Alzheimer’s disease.
    Kurzfassung: This book provides an overview of the biology and biochemistry of peroxisomes, and discusses the contribution of these organelles to peroxisomal and neurodegenerative diseases. It begins with a detailed introduction to the biogenesis and metabolic functions of peroxisomes, and highlights their role in oxidative stress and in lipid metabolism such as fatty acid oxidation. The following chapters focus on the molecular and clinical aspects of peroxisomal disorders caused by defects in peroxisomal function. In particular, the biological aspects of peroxisomal biogenesis disorders such as Zellweger syndrome and Heimler syndrome are discussed. This includes their underlying genetic causes as well as the biochemical and metabolic defects associated with the disorders. In addition, several chapters cover recent observations suggesting an association between peroxisomal dysfunction and neurodegenerative diseases such as Alzheimer's, Multiple Sclerosis and other degenerative cerebellar pathologies. The final section of the book discusses important cell and animal models for studying the role of peroxisomes in human diseases and presents current therapeutic strategies for their treatment. This book deals with a highly topical subject that is at the heart of current research, and represents a valuable contribution for all students and researchers who want to understand the complex biology of peroxisomes and their role in human diseases.
    Materialart: Online-Ressource
    Seiten: X, 212 p. 44 illus., 38 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030602048
    Serie: Advances in Experimental Medicine and Biology, 1299
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 53
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Medical genetics. ; Neuroscience. ; Medical Genetics.
    Beschreibung / Inhaltsverzeichnis: In Silico and In Vivo Studies on Quercetin as Potential Anti- Parkinson Agent -- Exhaled Breath Condensate (EBC). Is it a viable source of biomarkers for lung diseases? -- Treatment development for Alzheimer's disease: how are we doing? -- Microbiome hijacking towards an integrative pest management pipeline -- Regulation and roles of autophagy in the brain -- Three-dimensional models for studying neurodegenerative and neurodevelopmental diseases -- Assessment of factors contributing to the enhancement of memory and cognitive abilities in the context of neurosciences -- Buccal Mucosa Biomarkers in Alzheimer’s Disease -- Engaging social interest and creating awareness for the behavioural and psychological symptoms of dementia -- Structural study of the DNA – Clock/Bmal1 complex provides insights for the role of cortisol, hGR and HPA axis in stress management and sleep disorders -- The Effects of Quantum Entanglement on Chromatin and Gene Expression -- Olive Oil Polyphenols in Neurodegenerative Pathologies -- Human pluripotent stem cells as in vitro models of neurodegenerative diseases -- Nutritional Lipidomics in Alzheimer's Disease -- Alzeheimer’s Disease Therapeutic Approaches -- Stress and Wellbeing of Psychiatry Trainees: A Literature Review -- Brief Cognitive Tests in the case of Dementia and Alzheimer’s Disease Early Diagnosis -- Synthesis, Molecular Docking studies and Biological Evaluation of N-Acylarylhydrazones as Anti-inflammatory agents -- Exosome biomarkers revolutionize preclinical diagnosis of neurodegenerative diseases and assessment of treatment responses in clinical trials -- Biomarkers as a different approach in prevention and treatment of drug addiction (preliminary study) -- Sleep disorders and Restless Leg Syndrome in hemodialysis patients in Greece: a cross-sectional study -- Craniofacial and neurological phenotype in a patient with de novo 18q microdeletion and 18p microduplication -- What do recent clinical trials teach us about the etiology of AD -- Developmental Biology and Transgenic Avian Embryology: Body Alterity Bioart Wet Lab -- Gene editing, sexual reproduction and the arts: the present, the future and the imagined -- Amyotrophic Lateral Sclerosis: Current status in diagnostic biomarkers -- Synthesis and Characterization of Biologically Significant, 5-[N,N-dialkylamino alkoxy] azaindole 2-one,3- thiosemicarbazones and 5-[N,N-dialkylamino alkoxy] azaindole 3-hydrazone, 2-ones -- Genetic counseling for adult-onset spinal and bulbar muscular atrophy (Kennedy syndrome). Multiple cases of prenatal testing in a family -- Transcriptomics and Metabolomics in Amyotrophic Lateral Sclerosis -- Ocimum Sanctum Linn: A Potential Adjunct Therapy for Hyperhomocysteinemia – Induced Vascular Dementia -- Alzheimer's disease: The role of mutations in protein folding.
    Kurzfassung: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people. .
    Materialart: Online-Ressource
    Seiten: XII, 262 p. 42 illus., 34 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030326333
    Serie: Advances in Experimental Medicine and Biology, 1195
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 54
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Emotions. ; Neuropsychology. ; Neuroscience. ; Emotion. ; Neuropsychology.
    Beschreibung / Inhaltsverzeichnis: Part I. Basic Principles of Cerebellar Function in Emotion -- Chapter 1. Introduction into the Role of the Cerebellum in Emotion -- Chapter 2. Principles of Brain and Emotion: Beyond the Cortico-Centric Bias -- Chapter 3. Cerebellum and Emotion Processing -- Chapter 4. Cerebellum and Emotion Recognition -- Chapter 5. Cerebellum and Emotion Memory -- Part II. Cells and Molecules of Emotions in the Cerebellum -- Chapter 6. Topography of Emotions in Cerebellum as Appraised by Functional Imaging -- Chapter 7. The Neurophysiology of the Cerebellum in Emotion -- Chapter 8. Non-invasive Brain Stimulation of the Cerebellum in Emotion -- Part III. Cerebellum and Emotion in High Order Domains -- Chapter 9. Reward-Based Learning and Emotional Habit Formation in the Cerebellum -- Chapter 10. Cerebellar Contribution to Emotional Body Language Perception -- Chapter 11. Influence of Pain on Cognitive Dysfunction and Emotion Dysregulation in Chiari Malformation Type I -- Chapter 12. Cerebellum and Emotion in Morality -- Chapter 13. Music and the Cerebellum -- Chapter 14. The Cerebellum and Beauty: The Impact of the Cerebellum in Art Experience and Creativity -- Chapter 15. Cerebellum and Emotion in Social Behavior -- Chapter 16. Cerebellum, Embodied Emotions, and Psychological Traits -- Part IV. Cerebellum and Emotion Disorders -- Chapter 17. The Cerebellum and Disorders of Emotion -- Chapter 18. Cerebellum and Neurorehabilitation in Emotion with a Focus on Neuromodulation -- Part V. Perspectives -- Chapter 19. Current and Future Perspectives of the Cerebellum in Affective Neurosciences.
    Kurzfassung: Emotions represent a critical aspect of daily life in humans. Our understanding of the mechanisms of regulation of emotions has increased exponentially these last two decades. This book evaluates the contribution of the cerebellum to emotion. It outlines the current clinical, imaging and neurophysiological findings on the role of the cerebellum in key aspects of emotional processing and its influence on motor and cognitive function and social behavior. In the first section, the reader is introduced to the contributions of the cerebellum to various emotion domains, from emotion perception and recognition to transmission and encoding. Subsequent chapters provide a comprehensive picture of the neurophysiology and topography of emotion in the cerebellum and illustrate the convergence of theoretical and empirical research. Additional chapters address the cerebellum's involvement in emotional learning, emotional pain, emotional aspects of body language and perception, and its relations to social cognition including morality, music, and art. Finally, neuropsychiatric aspects of the cerebellum's influence on mood disorders and the current state of therapeutic options, including noninvasive stimulation approaches, complete the overview. This is the first book summarizing the current state of knowledge on the contribution of the cerebellum to important aspects of emotion. It is an essential reference for students, trainees, neuroscientists, researchers, and clinicians in neuroscience, neurology, neurosurgery and psychology involved in the study of emotions. The authors are renowned scientists in the field of cerebellar research.
    Materialart: Online-Ressource
    Seiten: XII, 313 p. 42 illus., 36 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030995508
    Serie: Advances in Experimental Medicine and Biology, 1378
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 55
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    Cham :Springer International Publishing :
    Schlagwort(e): Computational neuroscience. ; Computer science. ; Artificial intelligence. ; Data structures (Computer science). ; Information theory. ; Computational Neuroscience. ; Computer Science. ; Artificial Intelligence. ; Data Structures and Information Theory.
    Beschreibung / Inhaltsverzeichnis: Part 1: Basic Facts and Ideas for a Brain -- Chapter 1: The brain is an organ for information processing -- Chapter 2: The organization and improvement of behavior.-Chapter 3: A neuronal realization of the survival algorithm -- Chapter4: On the structure and function of cortical areas -- Part 2: Thinking in Cell Assemblies -- Chapter 5: Cognitive mental processes realized by cell assemblies in the cortex -- Chapter 6: A Model of Language Understanding by Interacting Cortical Areas -- Chapter 7: Can we accept a mechanistic description of our mental processes? -- Part 3: Further Developments until Today -- Chapter 8: Developments in Computer Science and Technical Applications -- Chapter 9: New Results from Brain Research and Neuroscience -- Chapter 10: Development of Brain Theory -- Chapter 11: Do we need Cognitive Neuroscience?. .
    Kurzfassung: In the new edition of Neural Assemblies, the author places his original ideas and motivations within the framework of modern and cognitive neuroscience and gives a short and focused overview of the development of computational neuroscience and artificial neural networks over the last 40 years. In this book the author develops a theory of how the human brain might function. Starting with a motivational introduction to the brain as an organ of information processing, he presents a computational perspective on the basic concepts and ideas of neuroscience research on the underlying principles of brain function. In addition, the reader is introduced to the most important methods from computer science and mathematical modeling that are required for a computational understanding of information processing in the brain. Written by an expert in the field of neural information processing, this book offers a personal historical view of the development of artificial intelligence, artificial neural networks, and computational cognitive neuroscience over the last 40 years, with a focus on the realization of higher cognitive functions rather than more peripheral sensory or motor organization. The book is therefore aimed at students and researchers who want to understand how the basic neuroscientific and computational concepts in the study of brain function have changed over the last decades.
    Materialart: Online-Ressource
    Seiten: XXI, 259 p. 87 illus., 10 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2022.
    ISBN: 9783031003110
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 56
    Schlagwort(e): Neurosciences. ; Nervous system Diseases. ; Developmental neurobiology. ; Neuroimmunology. ; Neuroscience. ; Neurological Disorders. ; Development of the Nervous System. ; Neuroimmunology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1_Glial Biology: A Historical Perspective -- Chapter 2_. Basic Biology of Astrocytes -- Chapter 3_ Oligodendrocyte: Structure, Function and Pathology -- Chapter 4_ Oligodendroglial-astroglial cell-cell communication in the Central Nervous System -- Chapter 5_ Oligodendroglial Gap junction communication in CNS myelination and demyelination -- Chapter 6_ Generation and maturation of macroglia in central nervous system. – Chapter 7_ Origin and Development of Microglia -- Chapter 8_ Biology of Astrocytes in CNS Infection -- Chapter 9_ Role of reactive astrocytes in Alzheimer’s disease -- Chapter 10_ Role of astrocyte dysfunction in Parkinson’s Disease pathogenesis -- Chapter 11_ Astroglial Pathology in Major Depressive Disorders: Metabolic and Molecular Aspects -- Chapter 12_ Glia in epilepsy: an overview -- Chapter 13_ Tumors of the Glia: Recent Advances -- Chapter 14_ Astroglial iron homeostasis and neurodegenerative diseases -- Chapter 15_ Glial cells are Key Orchestrators of Neural degeneration in Basal Ganglia Disorders: Classical and Contemporary observations -- Chapter 16_ Interplay between microglia and astrocytes during neuroinflammation: Lessons learnt from in-vitro and in-vivo models of sporadic Amyotrophic Lateral Sclerosis -- Chapter 17_ Microglia orchestrate inflammation via HSP60 driven signaling pathway: a road map of molecular mechanism -- Chapter 18_ Biphasic Role of Microglia in Brain Health and Disease -- Chapter 19_ Multidimensional roles of Microglial Cells in Neuroviral Infections -- Chapter 20_ Microglia Aging -- Chapter 21_ Emerging Role of Satellite and Schwann Cells of Peripheral Neuroglial System in Nerve Repair -- Chapter 22_ Insights in the role of glia in mediating brain plasticity in health and disease -- Chapter 23_ The glial perspective of energy homeostasis, neuroinflammation and neuro-nutraceuticals -- Chapter 24_ Role of glia in Huntington’s disease -- Chapter 25_ Endogenous mediators of neuroinflammation: The endocannabinoid system at the retina -- Chapter 26_ Drosophila melanogaster: An Immaculate Model for Glial Research -- Chapter 27_In-vitro models of Astrocytes: An Overview.
    Kurzfassung: This book reviews the role of glial cells (astrocytes, microglia, oligodendroglia, satellite cells, and Schwann cells) in neuronal health and diseases. It discusses the latest advances in understanding their origin, differentiation, and hemostasis. The book also examines the role of microglial cells in central nervous system (CNS) development, maintenance, and synaptic plasticity. Further, the book presents the functions of astrocytes in healthy CNS and their critical role in CNS disorders, including Parkinson's and Alzheimer's diseases. Notably, the book describes the pathobiology, molecular pathogenesis, stem cells, and imaging characteristics of gliomas. It defines the role of glial cells in regulating iron homeostasis and their effect on the neurodegeneration of neurons. Lastly, it covers the structure, function, and pathology of oligodendrocytes and their role in neuronal health and disease.
    Materialart: Online-Ressource
    Seiten: XXXIV, 745 p. 82 illus., 75 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811683138
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 57
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    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Food science. ; Biology. ; Physiology. ; Therapeutics. ; Neurology . ; Neuroscience. ; Food Science. ; Biological Sciences. ; Physiology. ; Therapeutics. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Aging and Neurodegeneration- A preface -- Chapter 2. Deciphering the molecular and genetic basis of Alzheimer’s disease -- Chapter 3. Tracking Neurodegeneration: Advancement in experimental study models -- Chapter 4. Pharmcological application of Phyllanthus emblica as therapeutics in Alzheimer’s disease -- Chapter 5. ROLE OF THE GUT MICROBIOME AND ITS MODULATION IN NEURODEGENERATIVE DISEASES -- Chapter 6. Recent advances in application of dietary polyphenols to treat age-related neurological disorders -- Chapter 7. PROPHYLAXIS THROUGH MARINE DERIVED BIOACTIVE COMPOUNDS TOWARDS NEURODEGENERATIVE DISORDERS -- Chapter 8. Recent advancements in omega fatty acids to treat neurodegeneration -- Chapter 9. Role of Alkoxyglycerol to Pause Tau Induced Alzheimer’s Disease -- Chapter 10. Application and Efficacy of Nano particle-based therapy Among Neurodegenerative Diseases -- Chapter 11. In silico techniques- Powerful tool for the development of therapeutics -- Chapter 12. Biomarkers: Potential perspectives in detection, diagnosis and prognosis of neurodegenerative disorders.
    Kurzfassung: This book provides a comprehensive summary of the latest knowledge regarding functional foods and new therapeutic strategies for neurodegenerative disorders through explaining specific mechanisms for natural remedies and functional foods as well as alternative treatment and supplementary approaches for neurodegenerative diseases. Many relevant topics are covered, including role of prebiotics, recent applications for dietary polyphenols, marine bioactive compounds for neuro disorders, and age-related disorders. The roles of various remedies and functional foods are explained for various types of diseases, and the book also integrates the role of functional foods and remedies to work with the current therapeutics that are taking place. In parallel, the information presented through this book will also stimulate current status of leading contemporary methods for prohylactic and diagnostic practices, comprising nanoparticles, biomarkers, in silico techniques, and CRISPR-mediated genome editing–based therapy. The book will be essential reading for students and researchers with an interest in natural medicine, drug development, and food therapeutic strategies. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
    Materialart: Online-Ressource
    Seiten: XVI, 222 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811667039
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 58
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Cognitive psychology. ; Art Philosophy. ; Neuropsychology. ; Philosophy of mind. ; Neuroscience. ; Cognitive Psychology. ; Philosophy of Art. ; Neuropsychology. ; Philosophy of Mind.
    Beschreibung / Inhaltsverzeichnis: Introduction on THINKING: Bioengineering of Science and Art -- Thinking as A Philosophical, Theological and Psychological Phenomenon -- How to Think about Human-Animal Differences in Thinking: Two Cases of Marginal Analogy in the Philosophical Explication of Animal Cognition -- Homo Pictor’: A Philosophical Enquiry into the Origins of Human Thinking -- Idealism and Science of Life: An Intersection between Philosophy and Biology -- Embodied Creativity and Symbolic Variation in The Evolution of Life -- Within the Box: Captives of our Own Mind -- The Dialectic of Mind and Matter in The Trialectic Approach: A New Path of The Cognition Process -- Efforts Deployed in the Penetration of “Thought” -- Pseudo-Thinking and Real Thinking -- Three Paradoxes of Thought: Thought Power Measured -- A New Philosophical Paradigm of Thinking for Particular Sciences: Physics, Cognitive Science, and Biology -- Indicators of Variation in Thinking Actions and Reactions -- Multidimensional Thinking: Economizing Thinking and Maximizing Outcomes -- How You Know What I Know That She Said About You: Theory of Mind, Intentionality and the Evolutionary Roots of Artistic Practice -- A Philosophical Perspective on the Bioengineering of Art: Ethical Shifts in Mimesis -- Thinking Through the Body: Art and Philosophy in Dialogue -- Mechanism vs. Organism: A Loosely Kantian Perspective and its Implications for Bioengineering -- New Media Art: The Liminal Space Between Thinking and Perceiving -- Towards a New Science of Interfaces: Bridging Art and Engineering -- Art as Metacognitive Tool for Critical Thinking in Engineering -- Dimensions of Thinking, Reflecting, and Knowing through Design -- Thinking Through Sound: Music Listening as A Model for Enhanced Cognition -- Poetic Thinking and the Constitution of Our World: On Language and Reality -- Thinking as the Invention of New Aspects within Language-Games -- Literature as a Genealogy of the Social Sciences Thought -- How Rational Thought Is Conceived in Christian Doctrine: The Case of Saint Thomas Aquinas -- The Interest of Religion on Ethical Thought in Science -- Thinking, Politics, and the Evolutionary Process of Societies -- Information Processing in Reasoning in the Environment of Forbidden Sentences -- The impact of economic science on human thinking -- Generations of Systems Thinking: Models for Future Learning -- Systems Thinking and Action for An Entrepreneurial Journey Towards the House of Lab Science -- Systems Approach for Modeling Multifactorial Human Interactions that Affect Ecological and Environmental Systems -- Cradle to Cradle and Cradle to Grave: Discussing the Case of Eco-Coffins -- THINKING 2050: Bioengineering of Science and Art.
    Kurzfassung: The “THINKING: Bioengineering of Science and Art” is to discuss about philosophical aspects of thinking at the context of Science and Art. External representations provide evidence that the fundamental process of thinking exists in both animal subjects and humans. However, the diversity and complexity of thinking in humans is astonishing because humans have been permitted to integrate scientific accounts into their accounts and create excellent illustrations for the effects of this integration. The book necessarily begins with the origins of human thinking and human thinking into self and others, body, and life. Multiple factors tend to modify the pattern of thinking. They all will come into play by this book that brings thinking into different disciplines: humanities, natural sciences, social sciences, formal sciences, and applied sciences. The thinking demands full processing of information, and therefore, the book considers the economy of thinking as well. The book thoroughly intends to explore thinking beyond the boundaries. Specifically, several chapters are devoted to discipline this exploration either by artistic thinking alone or by art and mathematics-aided engineering of complexities. In this manner, the book models variations on thinking at the individual and systems levels and accumulates a list of solutions, each good for specific scenarios and maximal outcomes. .
    Materialart: Online-Ressource
    Seiten: XVI, 803 p. 206 illus., 131 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031040757
    Serie: Integrated Science, 7
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 59
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    Cham :Springer International Publishing :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Cognitive neuroscience. ; Psychiatry. ; Behavioral Neuroscience. ; Cognitive Neuroscience. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Discovery science chapters -- Effects of AEDs on behaviour -- How to separate effects of seizures when studying behaviour -- Depression-like behaviour in epilepsy models -- Are behavioural deficits core components of epilepsy? -- Does stress trigger seizures: evidence from animal models? -- Early life stress and epilepsy -- disease models and epilepsy -- Disease modification in epilepsy: behavioural accompaniments -- Clinical chapters -- Do psychotropic drugs cause epileptic seizures? A review of the available evidence. Peri-ictal and para-ictal psychiatric phenomena: a relatively common yet unrecognized disorder -- Can we anticipate and prevent the occurrence of iatrogenic psychiatric events caused by antiepileptic drugs and epilepsy surgery? -- Are psychiatric disorders a risk for the development of treatment-resistant epilepsy? Temporal lobectomy: does it worsen or improve presurgical psychiatric disorders? -- Suicidality in epilepsy: does it share common pathogenic mechanisms with epilepsy? -- Psychotic disorders in epilepsy: do they differ from primary psychosis? -- Do neurobiologic aspects of primary psychiatric disorders account for the relatively high prevalence of psychiatric comorbidities in epilepsy? -- Are psychogenic non-epileptic seizures really the expression of a psychogenic process?
    Kurzfassung: Many people living with epilepsy also suffer from debilitating psychiatric and cognitive disorders. While these comorbidities have been recognized for centuries, their causation, and relationship to the epilepsy remains clouded in mystery. This volume highlights recent knowledge and findings as well as controversies in our current understanding of behavioral and psychiatric comorbidities of epilepsy.
    Materialart: Online-Ressource
    Seiten: X, 351 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031032356
    Serie: Current Topics in Behavioral Neurosciences, 55
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 60
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    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Pharmacology. ; Medicine Research. ; Biology Research. ; Neuropsychology. ; Neurology . ; Neuroscience. ; Pharmacology. ; Biomedical Research. ; Neuropsychology. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: 1.Determination of ketamine in the river of China -- 2.Ketamine abuse in Taiwan -- 3.Ketamine problem in Hong Kong -- 4. Hair analysis of ketamine -- 5. Brain imaging of ketamine abusers -- 6.Management of complications of ketamine abuse -- 7.Action site of ketamine in the NMDA receptor channel -- 8.Synaptic modulation in the effect of ketamine -- 9.Rodents whole-brain imaging in the effects of ketamine -- 10. Behavioral pharmacology of ketamine: An overview of preclinical studies -- 11.Antidepressant potential of ketamine enantiomers -- 12.Effects of ketamine on pain-related depression -- 13.Role of gut microbiota in the antidepressant actions of ketamine and its enantiomers -- 14. The role of NMDA receptor GluN2D subunit in the effects of ketamine and enantiomers -- 15.Roles of the lateral habenula in the actions of ketamine -- 16.Comparison of antidepressant action of ketamine and group II mGlu receptor antagonists -- 17.Antidepressant effects of ketamine in Taiwanese patients with treatment-resistant depression.
    Kurzfassung: This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants. .
    Materialart: Online-Ressource
    Seiten: V, 189 p. 27 illus., 13 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811529023
    DDC: 612.8
    Sprache: Englisch
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  • 61
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    Cham :Springer International Publishing :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Sex. ; Behavioral Neuroscience. ; Gender Studies.
    Beschreibung / Inhaltsverzeichnis: 1-Measuring Sex Differences and Similarities -- 2-Prenatal Steroid Hormones and Sex Differences in Juvenile Rhesus Macaque Behavior -- 3-Biological Approaches to Studying Gender Development -- 4-Social Influences on Gender Development: Theory and Context -- 5-Contemporary Cognitive Approaches to Gender Development: New Schemas, New Directions, and New Conceptualizations of Gender -- 6-Origins and Consequences of Childhood Gender Segregation: Towards an Integrative Developmental Systems Model -- 7-Gender, Toys, and Play: How Gendered Early Experiences Shape Later Development -- 8-Family Gender Socialization in Childhood and Adolescence -- 9-Gender Stereotypes and Education -- 10-Gender-Based Discrimination in Childhood and Adolescence -- 11-Gender and Sexuality in Disorders/Differences of Sex Development -- 12-Sexuality Development in Childhood -- 13-Sexual Pleasure in Adolescence: A Developmental Sexual Embodiment Perspective -- 14-Pornography Use in Adolescence and Young Adulthood -- 15-A Review of Theoretical Models and Lifespan Approaches to the Study of Sexual Offending -- 16-Learned but Not Chosen: A Reward Competition Feedback Model for the Origins of Sexual Preferences and Orientations -- 17-Carving the Biodevelopment of Same-Sex Sexual Orientation at Its Joints -- 18-Mental Health Among LGBT Youth -- 19-Asexuality: When Sexual Attraction is Lacking -- 20-Erotic Target Identity Inversions -- 21-Consensual Non-monogamy from a Developmental Perspective.
    Kurzfassung: This book showcases a wealth of knowledge and insight on gender and sexuality development. With contributions from leading researchers, it covers a comprehensive set of topics at the forefront of the field and strikes a balance between traditional and emerging areas of study. Given that gender and sexuality are shaped by myriad influences, this book is modelled on an interdisciplinary perspective and delves into biological, comparative, psychological, cognitive, social, cultural, and clinical approaches. In so doing, this collection conveys the rich tapestry of gender and sexuality science and will hold value for many. For those already in the field, this book provides an excellent resource for brushing up on the latest and for inspiring the next phases of scientific investigation. Those who are newer to the field, including undergraduate and graduate students, stand to gain tremendously from not only the thoughtful and informative content, but also from the interdisciplinary approach modelled throughout the book. Beyond academia, this book is a valuable resource for clinicians and policy makers who deal with child and adolescent issues.
    Materialart: Online-Ressource
    Seiten: XXIII, 636 p. 21 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030842734
    Serie: Focus on Sexuality Research,
    DDC: 612.8
    Sprache: Englisch
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  • 62
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    Cham :Springer International Publishing :
    Schlagwort(e): Psychobiology. ; Human behavior. ; Physical anthropology. ; Cognitive psychology. ; Animal welfare Moral and ethical aspects. ; Animal migration. ; Animal culture. ; Behavioral Neuroscience. ; Physical-Biological Anthropology. ; Cognitive Psychology. ; Animal Ethics. ; Animal Migration. ; Animal Science.
    Beschreibung / Inhaltsverzeichnis: Part I: Introduction -- Chapter 1: Recent developments in primatology and their relevance to the study of Tibetan macaques -- Part II: Social Behavior and Dynamics in Tibetan Macaques -- Chapter 2: Social and Life History Strategies of Tibetan Macaques at Mt. Huangshan -- Chapter 3: Size Matters in Primate Societies: How Social Mobility Relates to Social Stability in Tibetan and Japanese Macaques -- Chapter 4: Behavioral exchange and interchange as strategies to facilitate social relationships in Tibetan macaques -- Chapter 5: Social relationships impact collective decision-making in Tibetan macaques -- Chapter 6: Considering Social Play in Primates: A Case Study in Juvenile Tibetan Macaques (Macacathibetana) -- Chapter 7: The Vocal Repertoire of Tibetan Macaques (Macacathibetana) and Congeneric Comparisons -- Chapter 8: Tibetan Macaque Social Style: Co-variant and Quasi-independent Evolution -- Part III: Evolution of Rituals: Insights from Bridging Behavior -- Chapter 9: Preliminary observations of female-female bridging behavior in Tibetan macaques (Macacathibetana) at Mt. Huangshan, China -- Chapter 10: Bridging Behavior and Male-Infant Interactions in Macacathibetana and M. assamensis: Insight into the Evolution of Social Behavior in the sinica Species-group of Macaques -- Part IV: Livingwith Microbes, Parasites, and Diseases -- Chapter 11: The gut microbiome of Tibetan macaques: composition, influencing factors and function in feeding ecology -- Chapter 12: Medicinal Properties in the Diet of Tibetan Macaques at Mt. Huangshan - A Case for Self-medication -- Chapter 13: Primate infectious disease ecology: Insights and future directions at the human-macaque interface -- Part V: Emerging Technologies in Primatology -- Chapter 14: High field MRI technology for behavioral and cognitive studies in macaques in vivo.
    Kurzfassung: This open access book summarizes the multi-disciplinary results of one of China’s main primatological research projects on the endemic Tibetan macaque (Macaca thibetana), which had continued for over 30 years, but which had never been reported on systematically. Dedicated to this exceptional Old World monkey, this book makes the work of Chinese primatologists on the social behavior, cooperation, culture, cognition, group dynamics, and emerging technologies in primate research accessible to the international scientific community. One of the most impressive Asian monkeys, and the largest member of its genus, the Tibetan macaque deserves to be better known. This volume goes a long way towards bringing this species into the spotlight with many excellent behavioral analyses from the field.- Frans de Waal, Professor of Psychology, Emory University, USA. Macaques matter. To understand primate patterns and trends, and to gain important insight into humanity, we need to augment and expand our engagement with the most successful and widespread primate genus aside from Homo. This volume focuses on the Tibetan macaque, a fascinating species with much to tell us about social behavior, physiology, complexity and the macaque knack for interfacing with humans. This book is doubly important for primatology in that beyond containing core information on this macaque species, it also reflects an effective integrated collaboration between Chinese scholars and a range of international colleagues—exactly the type of collaborative engagement primatology needs. This volume is a critical contribution to a global primatology. - Agustín Fuentes, Professor of Anthropology, University of Notre Dame, USA. I have many fond memories of my association with Mt. Huangshan research beginning in 1983, when together with Professor Qishan Wang we established this site. It is such a beautiful place and I miss it. It is gratifying to see how far research has progressed since we began work there, becoming more internationalized and very much a collaborative endeavor under the long-term direction of Professor Jin-Hua Li and colleagues. This book highlights the increased interest in this species, representing a variety of disciplines ranging from macro aspects of behavior, cognition and sociality, to micro aspects of microbes, parasites and disease, authored by a group of renowned Chinese and international primatologists. I applaud their efforts and expect more interesting work to come from this site in the years ahead.- Kazuo Wada, Professor Emeritus, Kyoto University, Japan.
    Materialart: Online-Ressource
    Seiten: XVI, 302 p. 93 illus., 59 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030279202
    Serie: Fascinating Life Sciences,
    DDC: 612.8
    Sprache: Englisch
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  • 63
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Biomedical engineering. ; Materials Analysis. ; Imaging systems. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Imaging Techniques. ; Biological Imaging.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Introduction -- Chapter 2: Neural Tissue and its Signals -- Chapter 3: Measurements -- Chapter 4: Source Models -- Chapter 5: Forward Models -- Chapter 6: Inverse Methods -- Chapter 7: Assessment -- Chapter 8: Applications.
    Kurzfassung: This textbook provides a comprehensive and didactic introduction from the basics to the current state of the art in the field of EEG/MEG source reconstruction. Reconstructing the generators or sources of electroencephalographic and magnetoencephalographic (EEG/MEG) signals is an important problem in basic neuroscience as well as clinical research and practice. Over the past few decades, an entire theory, together with a whole collection of algorithms and techniques, has developed. In this textbook, the authors provide a unified perspective on a broad range of EEG/MEG source reconstruction methods, with particular emphasis on their respective assumptions about sources, data, head tissues, and sensor properties. An introductory chapter highlights the concept of brain imaging and the particular importance of the neuroelectromagnetic inverse problem. This is followed by an in-depth discussion of neural information processing and brain signal generation and an introduction to the practice of data acquisition. Next, the relevant mathematical models for the sources of EEG and MEG are discussed in detail, followed by the neuroelectromagnetic forward problem, that is, the prediction of EEG or MEG signals from those source models, using biophysical descriptions of the head tissues and the sensors. The main part of this textbook is dedicated to the source reconstruction methods. The authors present a theoretical framework of the neuroelectromagnetic inverse problem, centered on Bayes’ theorem, which then serves as the basis for a detailed description of a large variety of techniques, including dipole fit methods, distributed source reconstruction, spatial filters, and dynamic source reconstruction methods. The final two chapters address the important topic of assessment, including verification and validation of source reconstruction methods, and their actual application to real-world scientific and clinical questions. This book is intended as basic reading for anybody who is engaged with EEG/MEG source reconstruction, be it as a method developer or as a user, including advanced undergraduate students, PhD students, and postdocs in neuroscience, biomedical engineering, and related fields. .
    Materialart: Online-Ressource
    Seiten: XIX, 415 p. 174 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030749187
    DDC: 612.8
    Sprache: Englisch
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  • 64
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Immunology. ; Psychiatry. ; Neuroscience. ; Immunology. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Preface -- A Brief History of Immunological Research into Psychosis and Pathways for Immune Influence of the Brain.-Basic Concept of Microglia Biology and Neuroinflammation in Relation to Psychiatry -- Epidemiological Studies of Prenatal and Childhood Infection and Schizophrenia -- Schizophrenia, Cytokines and Other Systemic Inflammatory Mediators [to include oxidative stress and lymphocyte alterations] -- Association between Schizophrenia, Microbial Infection and Microbiota -- Autoantibodies and psychosis -- Effect of Infection on Cognition in Schizophrenia and Healthy People -- Role of Infection, Autoimmunity, Atopic Disorders and the Immune System in Schizophrenia: Evidence from Epidemiological and Genetic Studies -- Microglial Activation and Psychotic Disorders: Evidence from Pre-clinical and Clinical Studies -- Early-Life Adversity, Systemic Inflammation, and Co-Morbid Physical and Psychiatric Illnesses of Adult Life -- Inflammation, Antipsychotic Drugs and Evidence for Effectiveness of Anti-inflammatory Agents in Schizophrenia.
    Kurzfassung: This book provides a comprehensive summary of the cutting edge scientific evidence regarding the role of immune system in the pathogenesis and treatment of schizophrenia and related psychotic disorders. It illustrates the role of inflammation and immunity in schizophrenia drawing on both basic science and clinical research. The chapters provide up-to-date summaries of immunological risk factors for schizophrenia and related psychotic disorders, and underlying mechanisms as informed by neuroimaging, genetic, clinical and animal experimental studies. In addition, the book will illuminate the scope for immunological treatment for schizophrenia. .
    Materialart: Online-Ressource
    Seiten: X, 244 p. 10 illus., 8 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030391416
    Serie: Current Topics in Behavioral Neurosciences, 44
    DDC: 612.8
    Sprache: Englisch
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  • 65
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Veterinary medicine. ; Neurology . ; Anatomy. ; Neuroscience. ; Veterinary Science. ; Neurology. ; Anatomy.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Rodent Taxonomic and biological data -- Basic Neurohistology -- Basic Neuroanatomy/ Coverings of the CNS/ Cerebrospinal fluid system -- Microscopic anatomy of the mouse brain -- The mouse spinal cord -- The mouse brainstem -- The mouse cerebellum -- The mouse dorsal thalamus -- The mouse hypothalamus.-The mouse cerebral cortex.-The mouse hippocampus.-The mouse amygdala -- The mouse caudate putamen -- The mouse oflactory system -- The mouse circle of Willis.
    Kurzfassung: This textbook describes the basic neuroanatomy of the laboratory mouse. The reader will be guided through the anatomy of the mouse nervous system with the help of abundant microphotographs and schemata. Learning objectives and summaries of key facts at the beginning of each chapter provide the reader with an overview on the most important information. As transgenic mice are one of the most widely used paradigms when it comes to modeling human diseases, a basic understanding of the neuroanatomy of the mouse is of considerable value for all students and researchers in the neurosciences and pharmacy, but also in human and veterinary medicine. Accordingly, the authors have included, whenever possible, comparisons of the murine and the human nervous system. The book is intended as a guide for all those who are about to embark on the structural, histochemical and functional phenotyping of the mouse’s central nervous system. It can serve as a practical handbook for students and early researchers, and as a reference book for neuroscience lectures and laboratories. .
    Materialart: Online-Ressource
    Seiten: XI, 350 p. 269 illus., 241 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030198985
    DDC: 612.8
    Sprache: Englisch
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  • 66
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Psychiatry. ; Psychobiology. ; Human behavior. ; Psychology, Experimental. ; Neuroscience. ; Psychiatry. ; Behavioral Neuroscience. ; Biological Psychology. ; Experimental Psychology.
    Beschreibung / Inhaltsverzeichnis: Overview chapter -- Imaging studies linking dopaminergic systems to impulsivity in humans -- The Genetics of Externalizing Problems -- The neuropharmacology of impulsive behaviour: ten years later -- Inhibitory control and impulsivity in childhood onset disruptive behavior disorders -- Steep discounting of future rewards as an impulsivity phenotype: a concise review -- Developmental considerations in impulsivity: Implications for research and treatment -- Reinforcer Pathology: Implications for Substance Abuse Intervention -- Impulsivity and Suicidal Behavior -- Sex differences in neural circuits underlying inhibitory control -- The role of impulsivity facets on the incidence and development of alcohol use disorders -- The neurobiology of reinforcement learning mechanisms in impulsivity.
    Kurzfassung: This volume provides an empirical and conceptual overview of advances in our understanding of impulsivity and impulsive behaviors. Prominent scientists review the range of behavioral phenomena referred to as ‘impulsive’, as well as the defining features and psychological, neurocognitive and behavioral processes that underlie of the manifestation of impulsive behaviors, focussing on progress made and the questions remaining to be answered.
    Materialart: Online-Ressource
    Seiten: VIII, 221 p. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030605117
    Serie: Current Topics in Behavioral Neurosciences, 47
    DDC: 612.8
    Sprache: Englisch
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  • 67
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Neurology . ; Anatomy. ; Neuroscience. ; Neurology. ; Anatomy.
    Beschreibung / Inhaltsverzeichnis: Overview of the Human Brain and Spinal Cord -- Vascularization of the Brain and Spinal Cord -- Notes on Techniques -- The Somatosensory System -- The Reticular Formation and the Neuromodulatory Systems -- The Cranial Nerves -- The Auditory System -- The Visual System -- Motor Systems -- The Cerebellum -- The Basal Ganglia -- The Autonomic Nervous System -- The Hypothalamus, the Preoptic Area and Hypothalamohypophysial Systems -- The Limbic System -- The Cerebral Cortex and Complex Cerebral Functions.
    Kurzfassung: Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death can progress through connections. Accordingly, knowing how the various parts of the brain are interconnected to form functional systems is a prerequisite for properly understanding data from all fields in the neurosciences. Clinical Neuroanatomy: Brain Circuitry and Its Disorders bridges the gap between neuroanatomy and clinical neurology. It focuses on human and primate data in the context of brain circuitry disorders, which are so common in neurological practice. In addition, numerous clinical cases are presented to demonstrate how normal brain circuitry can be interrupted, and what the effects are. Following an introduction to the organization and vascularization of the human brain and the techniques used to study brain circuitry, the main neurofunctional systems are discussed, including the somatosensory, auditory, visual, motor, autonomic and limbic systems, the cerebral cortex and complex cerebral functions. In this 2nd edition, apart from a general updating, many new illustrations have been added and more emphasis is placed on modern techniques such as diffusion magnetic resonance imaging (dMRI) and network analysis. Moreover, a developmental ontology based on the prosomeric model is applied, resulting in a more modern subdivision of the brain. The new edition of Clinical Neuroanatomy is primarily intended for neurologists, neuroradiologists and neuropathologists, as well as residents in these fields, but will also appeal to (neuro)anatomists and all those whose work involves human brain mapping.
    Materialart: Online-Ressource
    Seiten: XVI, 981 p. 509 illus., 325 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2020.
    ISBN: 9783030418786
    DDC: 612.8
    Sprache: Englisch
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  • 68
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Pediatrics. ; Bioinformatics. ; Clinical health psychology. ; Critical psychology. ; Neuroscience. ; Pediatrics. ; Computational and Systems Biology. ; Health Psychology. ; Critical Psychology.
    Beschreibung / Inhaltsverzeichnis: Part 1: Mechanisms underlying brain changes during sensitive periods -- Development of functional properties in the early visual system: new appreciations of the roles of lateral geniculate nucleus -- Maturation of Corticolimbic Functional Connectivity during Sensitive Periods of Brain Development -- Microglia and sensitive periods in brain development -- Is Adolescence a Sensitive Period for the Development of Incentive Reward Motivation? Part 2: The influences of positive and negative factors during sensitive periods -- Physical Activity, Fitness and Executive Functions in Youth: Effects, Moderators and Mechanisms -- Nutrition and brain development.-Understanding sensitive period effects in musical training -- Sensitive periods for recovery from early brain injury -- Part 3: Community level impact of sensitive periods: analyses and applications -- Statistical Modeling of Sensitive Period Effects Using the Structured Life Course Modeling Approach (SLCMA) -- Capitalizing on neuroplasticity across development to redirect pathways from juvenile justice involvement.
    Kurzfassung: Sensitive periods occur when unique experiences permanently influence brain development either by their presence or absence. This volume covers underlying brain systems and behaviors that are sculpted by the environment in humans and animals in a search for commonalities. The mechanisms involved, the importance of timing in the process, and factors that can change the brain are discussed in this exciting book. Different chapters examine how experience guides the development of cells, circuits, and function using vision, cortical circuits, and cognition as frameworks. Scientific evidence for effective preventative intervention approaches, including diet, exercise, and music, are included to find ways to maximize child and adolescent development. The adverse effects of early brain injury are also included. As sensitive periods are gaining importance in their application in the real-world, novel statistical approaches for human studies are presented and the importance of sensitive periods are covered by examining the juvenile justice system. The book has interdisciplinary appeal and scholars with an interest in brain resiliency or vulnerability will find it of particular interest.
    Materialart: Online-Ressource
    Seiten: XII, 254 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031044731
    Serie: Current Topics in Behavioral Neurosciences, 53
    DDC: 612.8
    Sprache: Englisch
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  • 69
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    Cham :Springer International Publishing :
    Schlagwort(e): Nervous system Regeneration. ; Alternative medicine. ; Neurology . ; Regeneration and Repair in the Nervous System. ; Complementary and Alternative Medicine. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Histopathological Basis for Acupuncture -- Current Advances in Mathematical Models of Initial Response to Mechanical Stimulation at Acupoint -- Signal Transduction in Acupoints -- Cellular Mechanisms in Acupuncture Effects -- Chemical and Physical Characteristics of Moxibustion -- Imaging of Acupuncture’s Effects: From Bedside to Bench -- Meridians – Neurosensory Organs within the System of Homeostatic Regulation -- Meridian-Viscera Correlationship: Theory and Mechanism of the Heart Meridian-Heart-Brain Interactions -- Autonomic Function and Electroacupuncture -- Understanding of Myofasial Trigger Points: Acupuncture verses Dry Needling -- Current Research in Silver Needle Acupuncture for Myofascitis -- Acupuncture in Supportive Care for Breast Cancer Survivors -- Alternative Therapies for Chemotherapy-Induced Peripheral Neuropathy -- Acupuncture and Related Techniques for Perioperative Care of Surgical Patients -- Hypothalamic-pituitary-adrenal Axis: A Bridge between acupuncture and diseases -- Neurobiological Mechanism of Acupuncture Analgesia in Chronic Somatic Pain -- Analgesic Effects of Acupuncture on Orofacial Pain -- Itch and the Antipruritic Effect of Acupuncture -- Acupuncture for Autism Spectrum Disorders -- Acupuncture Treatment for Multiple Sclerosis -- The Clinical and Experimental Study on Acupuncture for Children with Cerebral Palsy -- Beneficial Effect of Acupuncture on Depressive Disorders -- Acupuncture and Alzheimer’s Disease -- Acupuncture Treatment for Alzheimer’s Disease -- Electroacupuncture against Ischemic Brain Injury: Efficacy, optimal conditions and Mechanisms.
    Kurzfassung: Written by over seventy scientists and clinicians worldwide from China, USA, Germany, Canada, Japan and other countries, this monograph, with nearly 450 figures and tables, covers a wide range of advanced progress in acupuncture research, from experimental research to clinical applications. In addition to exploring the histopathological basis for acupuncture and mathematical simulation of acupoint response to stimulation, initiation and transduction of acupuncture signals and cellular mechanisms during acupuncture effects as well as chemical and physical characteristics of moxibustion on acupoints are broadly discussed. The topics also include novel data on acupuncture effect with advanced imaging techniques, a unique understanding of meridian-viscera correlation, specific interactions between meridians and neurosensory organs within the system of homeostatic regulation and the acupuncture-induced influences on autonomic function. Several chapters introduce specific approaches with dry needling, silver needling and stainless needling for certain diseases, such as myofascitis, supportive care for breast cancer and chemotherapy-induced peripheral neuropathy as well as perioperative care of surgical patients. Moreover, this book discusses recent research on acupuncture therapy and potential mechanisms for a number of severe and refractory neurological disorders, including hyperactivity of hypothalamic-pituitary-adrenal axis, orofacial pain, chronic pain, itch, multiple sclerosis, autism spectrum disorders, cerebral palsy, depressive disorders, Alzheimer’s disease and ischemic brain injury. The vast amount of information offered in this book provides a comprehensive perspective on advanced acupuncture research to not only acupuncturists, but also to neuroscientists, neurologists, and other clinicians. For medical students and graduate and undergraduate students majoring in biology, physiology and neuroscience, this book offers an advanced course in learning about the mechanism-driven advances in alternative and complementary medicine. * Contains a comprehensive summary of the latest advances in acupuncture research from all over the world * Provides an easy-to-navigate reference for acupuncture researchers and neuroscientists alike * Combines basic and clinical knowledge of acupuncture and explores the molecular and neurobiological mechanisms that underlie it.
    Materialart: Online-Ressource
    Seiten: XXIX, 750 p. 423 illus., 362 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030962210
    DDC: 612.8
    Sprache: Englisch
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    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Nutrition   . ; Microbial populations. ; Nervous system Diseases. ; Neuroscience. ; Nutrition. ; Microbial Communities. ; Neurological Disorders.
    Beschreibung / Inhaltsverzeichnis: Gut Microbiome Brain Axis: An Introduction -- Cross talk between gut microbiota and host immune cells -- Microbiota-Gut-Brain Axis and Neurodegenerative Disorder -- Gut Microbiota Regulation of Cerebral Stroke -- Aging: Impact of Gut Microbiota -- Gut Microbiome Regulation of Appetite and Neurological Disorders -- Human diets, Gut microbiome and Neuroinflammation -- Dietary Fatty acids, Gut microbiome and Gut-Brain communication: A Current perspective -- Role of Short Chain Fatty Acids from Gut Microbiota in Neuroendocrine Pathogenesis Management -- Potential role of probiotics on gut microbiota in neurological disease -- Reversal of metabolic disorder through the restoration of gut microbiota -- Gut Microbiome and Diet: Promising Approach for Treatment of Cognitive Impairment -- Nanoplastics, Gut microbiota and Neurodegeneration -- Gut Microbiome, COVID-19, and Neurological Impairment -- Tools to study Gut Microbiome -- Germ-Free Mice Technology: opportunity for Future Research -- Gut Microbiome and Neurodegeneration: A Bioinformatics Approach.
    Kurzfassung: This book provides an overview of bidirectional communication between gut-microbiome-brain, pathways, nutrients, and metabolites that are involved in microbiota gut-brain axis (MGBA) interactions. Further it reviews the relevance of this axis in the neurological disorders and potential therapeutic interventions, involving gut microbiome or probiotics and prebiotics which can ameliorate the neurological disorders. The book examines the role of gut microbiota in the establishment and hemostasis of innate immune response and explores the possibility of development of microbiome-targeted therapeutic interventions. Notably, the book discusses the role of the gut microbiota and immune system on the maintenance of brain functions and the development of neurological disorders. It also highlights the recent advances in improving neurological diseases by phytochemicals, prebiotics and probiotics. This book is useful for researchers working in neuropharmacology, Clinical Research, toxicology, neurodegeneration, and stroke biology.
    Materialart: Online-Ressource
    Seiten: IX, 311 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811945304
    Serie: Nutritional Neurosciences,
    DDC: 612.8
    Sprache: Englisch
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    Schlagwort(e): Neurosciences. ; Nutrition   . ; Nervous system Diseases. ; Neuroscience. ; Nutrition. ; Neurological Disorders.
    Beschreibung / Inhaltsverzeichnis: Part 1: Neurological disorders from Background to interplay of Genetic, Epigenetic and Environmental risk factors -- Chapter 1: Phytonutrients in Neurological Disorders -- Chapter 2: Psychobiotics in health, longevity and neurological disorders -- Chapter 3: Nutritional, dietary, and lifestyle approaches for prevention and management of Alzheimer’s disease.-Chapter 4: Qualitative and Analytical Treatment of Nonlinear Dynamical systems in Neurological Diseases -- Chapter 5: Impact of a psychological follow-up of diabetics in the management of diabetes in Morocco -- Chapter 6: Neuroprotective and anxiolytic effects of date seeds phenolic compounds in Nicotinamide-Streptozotocin-Induced type 2 diabetic rats -- Chapter 7: Role of nutrition in pathogenesis of neurological disorders -- Part 2: Specific Food and Nutritional Qualities on Neruological Disorders -- Chapter 8: Best foods for repair of brain damage -- Chapter 9: Role of micronutrients in neurological development -- Chapter 10: Algae as a potential vegetative source of PUFA for the prevention of neurological disorders -- Chapter 11: Natural foods for suppressing Dementia -- Chapter 12: Nutrients' role in the treatment of Parkinson's and Alzheimer's diseases -- Chapter 13: Novel marine derived natural products for the treatment of depressive disorder -- Chapter 14: Nanoceuticals as Theranostics against Neurodegenerative diseases -- Chapter 15: Role of Antioxidant Nutraceuticals in Neurodegenerative diseases -- Part 3: Herbal remedies for Neurological disorders -- Chapter 16: Herbal drugs: Its molecular mechanism to prevent Alzheimer’s disease with special reference to non-phenolic secondary metabolites -- Chapter 17: Preventive Role And Mechanism Of Herbal Medicine In Alzheimer’s Disease With Special Reference To Phenolic Compounds -- Chapter 18: Herbal Remedies for Autism -- Chapter 19: Action of herbal products in suppressing Parkinson’s Disorder -- Chapter 20: Impact of diet on neurotransmitters.
    Kurzfassung: This book provides the latest research on the role of nutrients in the prevention and treatment of neurological disorders. It discusses dietary supplements and dietary restrictions for combating neurological disorders, including Alzheimer’s disease, Parkinson’s disease, stroke, and epilepsy. The book also explains the impact of different nutrients such as herbal products, algae, micronutrients in stimulating the brain and central nervous system during abnormal functions. It covers the effect of the nutrients on the function of neurotransmitters, their stimulatory effect in autism, dementia, Alzheimer’s, and other neuropathological states. The book also defines the mechanistic effects of neuroprotective and psycho protective effects of natural food in repairing brain damage. This book is essential reading for neuroscientists and neurologists, and healthcare professionals.
    Materialart: Online-Ressource
    Seiten: XVIII, 383 p. 45 illus., 24 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811681585
    Serie: Nutritional Neurosciences,
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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    Cham :Springer International Publishing :
    Schlagwort(e): Neurosciences. ; Evolution (Biology). ; Psychology. ; Neuroscience. ; Evolutionary Biology. ; Behavioral Sciences and Psychology.
    Beschreibung / Inhaltsverzeichnis: Chapter. 1. Introduction -- Chapter. 2. Eusociality -- Chapter. 3. Brain and social environment -- Chapter. 4. Socio-biological interactions -- Chapter. 5. Social Inequality -- Chapter. 6. Culture and evolution -- Chapter. 7. Means of social coercion -- Chapter. 8. Population growth and the collective brain -- Chapter. 9. Tooling and technology -- Chapter. 10. The Homo sapiens, evolution of the warmonger human -- Chapter. 11. Factors of our human future -- Chapter. 12. On the human dimension -- Chapter. 13. Our species’ hypothetical alternatives.
    Kurzfassung: This book approaches two behavioral domains involved with human nature and actions related to dominance, an ancient animal, survival-linked, behavioral drive anchored in basal neural brain circuits. These domains result in latent or manifest conflicts among components of human animal nature and cultural profiles. The first domain refers to evolutive animal behavioral inertias that affect the basic construction of our brain/mind and social behavioral spectrum, underneath cultural and political enclosures. The second domain is considered a consequence of the previous one and involves the concept that the basic animal behavioral drive of dominance interferes with the expression of a truly human, cooperative social construction, and fosters conflicts (based on profit or comparative advantage). This drive tints or conditions our behavior in all its expressions (parochial, social, political, financial, religious, cognitive development). It also fosters social detachment of elite minorities –financially powerful and drivers of human evolutionary trends– from general concerns and collective needs of legions of subdued populations. Additionally, the latter promotes Star Wars factual chimeras and expanding dominance/prevalence and power grip beyond earthbound objectives that promote spatial exploration and scientific objectives. The quest for knowledge is embedded in our behavioral construction but employed by opportunistic – political – strategies that seek dominance/prevalence. Basic, ancestral, animal drives, here focused on dominance, lie underneath our sociocultural expressions, and feed construction of survival, ideology, class prejudices, submissiveness, cooperativity, and technological development. On top of this basic drive, humans have construed additional relational levels (whether of cognitive or emotional nature) expressed as cultural constructions that provide means to attempt to approach a socially acceptable format and public support. Whenever these processes collide or collapse, individual and collective standings tend to generate social changes or individual or collective pathologies. This book should be an exciting read for all those enthusiasts of the human mind, behavior, and cultural evolution ranging from fields such as neuroscience and biology to political sciences and anthropology. Given the breadth of studies as well as the clear language used by the author, students will find this book as a resourceful material for the undergraduate and graduate studies.
    Materialart: Online-Ressource
    Seiten: XIII, 155 p. 15 illus., 4 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030974015
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 73
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    Online-Ressource
    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Life sciences. ; Biophysics. ; Medical genetics. ; Neural networks (Computer science) . ; Neuroscience. ; Life Sciences. ; Biophysics. ; Medical Genetics. ; Mathematical Models of Cognitive Processes and Neural Networks.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. Noise and Randomness in Science and Engineering -- Chapter 3. Various Types of Noise and their Sources -- Chapter 4. Constructive Role of Noise and Nonlinear Dynamics -- Chapter 5. Noise and Synchronization of Oscillatory Networks -- Chapter 6. Stochastic Fluctuations at Cellular and Molecular level -- Chapter 7. Various Types of Noise and their Sources in Living Organisms -- Chapter 8. Ion Channel Noise in Biological Systems -- Chapter 9. Noise in Cellular Communication -- Chapter 10. The Role of Noise in Brain Function -- Chapter 11. Noise and Gene Oscillators -- Chapter 12. Developmental Noise and Stability -- Chapter 13. Noise and Coherence in Meditation -- Chapter 14. Chaos, Stochasticity and Noise -- Chapter 15. Chance, Determinism and Laws of Nature.
    Kurzfassung: This book illustrates the role of randomness and noise in living organisms. Traditionally, the randomness and noise have been used in understanding signal processing in communications. This book is divided into two sections, the first of which introduces readers to the various types and sources of noise and the constructive role of noise in non-linear dynamics. It also analyses the importance of randomness and noise in a variety of science and engineering applications. In turn, the second section discusses in detail the functional role of noise in biological processes for example, in case of brain function at the level of ion channel, synaptic level and even at cognitive level. These are described in various chapters. One of the challenging issue finding the neuronal correlates of various meditative states is to understand how brain controls various types of noise so as to reach a state of synchronized oscillatory state of the brain corresponding to the state of Samadhi. This is described in details in one chapter called Noise, Coherence and meditation. The concept of noise and the role of randomness in living organism raise lot of controversy for last few decades. This is discussed in a separate chapter. Finally, the epistemic and ontic nature of randomness as discussed in physical science are investigated in the context of living organism.
    Materialart: Online-Ressource
    Seiten: XVII, 160 p. 16 illus., 10 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811695834
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 74
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    Singapore :Springer Nature Singapore :
    Schlagwort(e): Neurosciences. ; Gerontology. ; Human physiology. ; Geriatrics. ; Cytology. ; Neuroscience. ; Gerontology. ; Human Physiology. ; Geriatrics. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. An Unsolved Problem in Gerontology Yet : The Molecular Mechanism of Biological Aging – A Historical and Critical Overview -- Chapter 2. Clinical and Basic Biology of Werner Syndrome, the Model Disease of Human Aging -- Chapter 3. Biomarkers of Healthy Longevity: Lessons from Supercentenarians in Japan -- Chapter 4. Cellular aging and metabolites in aging -- Chapter 5. To G0 or Not to G0: Cell Cycle Paradox in Senescence and Brain Aging -- Chapter 6. C. elegans longevity genes -- Chapter 7. Understanding the functions of longevity genes in Drosophila -- Chapter 8. NAD+ metabolism in Aging -- Chapter 9. Mitochondrial dysfunction and growth differentiation factor 15 in aging -- Chapter 10. Sirtuins and metabolic health -- Chapter 11. Autophagy in aging and longevity -- Chapter 12. Sarcopenia: current topics and future perspective -- Chapter 13. Osteoporosis and cellular senescence in bone -- Chapter 14. Aging and chronic kidney disease viewed from the FGF-Klotho endocrine system -- Chapter 15. Aging biomarker SMP30 into a new phase of vitamin C and aging research -- Chapter 16. Age-related memory impairments are caused by alterations in glial activity at old ages -- Chapter 17. Critical Roles of Glial Neuroinflammation in Age-Related Memory Decline -- Chapter 18. Central mechanisms linking age-associated physiological changes to healthspan through the hypothalamus -- Chapter 19. PET imaging of amyloid and tau in Alzheimer’s disease -- Chapter 20. Presenilin/γ-secretase in the pathogenesis of Alzheimer disease -- Chapter 21. Amyloid-β in brain aging and Alzheimer’s disease -- Chapter 22. Tau Pathology and Neurodegenerative Disorders -- Chapter 23. Aging and Parkinson’s disease: pathological insight on model mice -- Chapter 24. Evaluating the brain aging through eyes: The Potential use of hyperspectral imaging cameras to diagnose Alzheimer's disease risk -- Chapter 25. Healthy Aging in Japan.
    Kurzfassung: This book describes the recent advancement of basic research on the biology of aging and longevity studies in various organisms, as well as the neurobiology of aging and neurodegeneration mechanisms. Chapters present new findings and conceptual developments concerning the basic mechanisms of aging and longevity determination. As a follow-up volume to the previous book Aging Mechanisms (2015), it overviews the rapid progress of aging research introducing new topics from leading laboratories in Japan. Chapter contributors are selected based on recent scientific achievements on the mechanisms of aging in various model organisms, including yeast, worm (C. elegans), fly (Drosophila), mice, and rats. Chapters are ordered from the discussion on molecular and cellular levels to physiological and systemic levels. The book also provides an overview of aging science in the region and helps readers quickly grasp who is doing what in this research area. As the aging of population becomes an ever more pressing issue in Asia, advancing the understanding of basic mechanisms of organism aging and longevity determination will be crucial to developing more effective therapies and protective strategies. Researchers and graduate students in biomedical aging research will find this as a rich source of information and a stimulus to novel research directions.
    Materialart: Online-Ressource
    Seiten: XVIII, 430 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811679773
    DDC: 612.8
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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