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  • Books  (6)
  • Medicine Research.  (6)
  • DD1-905
  • Cham :Springer International Publishing :  (6)
  • De Gruyter
  • München : Beck
  • 612  (6)
  • 1
    Keywords: Human physiology. ; Medicine Research. ; Biology Research. ; Proteins . ; Biological transport. ; Cell membranes. ; Human Physiology. ; Biomedical Research. ; Protein Biochemistry. ; Membrane Trafficking.
    Description / Table of Contents: 1. Na+/K+-ATPase Drives Most Asymmetric Transports and Modulates the Phenotype of Epithelial Cells -- 2. Na+-K+-2Cl- Cotransporter -- 3. Thiazide-sensitive NaCl Cotransporter -- 4. NBCe1, an Electrogenic Na+ Bicarbonate Cotransporter, in Epithelia -- 5. Na+/H+ Exchangers in Epithelia -- 6. Sugar Transport Across Epithelia -- 7. Amino Acid Transporters of Epithelia -- 8. Structure-Dynamic and Regulatory Specificities of Epithelial Na+/Ca2+ Exchangers (NCX) -- 9. Urea Transporters in Health and Disease -- 10. H,K-ATPases in Epithelia -- 11. Zinc Transporters Involved in Vectorial Zinc Transport in Intestinal Epithelial Cells -- 12. Properties, Structure and Function of the Solute Carrier 26 Family of Anion Transporters -- 13. ClC-2 Chloride Channels -- 14. The Role of the Endosomal Chloride/Proton Antiporter ClC-5 in Proximal Tubule Endocytosis and Kidney Physiology -- 15. CFTR and Cystic Fibrosis: A Need for Personalized Medicine -- 16. Molecular Physiology and Pharmacology of the Cystic Fibrosis Transmembrane Conductance Regulator -- 17. TMEM16 Proteins (Anoctamins) in Epithelia -- 18. Epithelial Sodium Channels (ENaC) -- 19. ROMK and Bartter Syndrome Type 2 -- 20. Inwardly-rectifying K+ channel 4.1 regulates renal K+ excretion in the aldosterone-sensitive distal nephron -- 21. Small-molecule Pharmacology of Epithelial Inward Rectifier Potassium Channels -- 22. KCa3.1 in Epithelia -- 23. BK Channels in Epithelia -- 24. Recent Developments in the Pharmacology of Epithelial Ca2+-Activated K+ channels -- 25. KCNE regulation of KCNQ channels -- 26. Orai Channels -- 27. Trp Channels in Renal Epithelia -- 28. P2X receptors in Epithelia -- 29. The Polycystins and Polycystic Kidney Disease -- 30. Renal Aquaporins in Health and Disease.
    Abstract: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. The authors will show, that each of these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their responsibility in maintaining homeostasis. The reader gains an understanding of the fundamentals of epithelial ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the third of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. The focus of this volume lies with different ion channel and transporter families. Additionally, this volume benefits from pharmaceutical contributors and their insights into recent pre-clinical drug discovery efforts and results from clinical trials. Overall, these chapters offer a more thorough coverage of individual epithelial ion channels and transporters from the 1st Edition, along with eleven new chapters. That makes Volume 3 an insightful contribution for physiology students, scientists and clinicians.
    Type of Medium: Online Resource
    Pages: XXI, 1244 p. 256 illus., 203 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030554545
    Series Statement: Physiology in Health and Disease,
    DDC: 612
    Language: English
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  • 2
    Keywords: Human physiology. ; Medicine Research. ; Biology Research. ; Pathology. ; Physiology. ; Human Physiology. ; Biomedical Research. ; Pathology. ; Animal Physiology.
    Description / Table of Contents: Salivary glands' anatomy and physiology -- Saliva in ingestive behavior research: association with oral sensory perception and food intake -- Saliva - a non-invasive sample: Pros and Cons -- Methodology assays for the salivary biomarkers’ identification and measurement -- The role of saliva in dental practice -- Salivary biomarkers in respiratory diseases -- Salivary biomarkers in neurologic diseases -- Salivary biomarkers in the diagnosis and monitoring of metabolic and endocrine diseases -- Salivary markers in inflammatory and autoimmune diseases -- Salivary biomarkers in oral and systemic pathologies. Kidney diseases -- Salivary diagnosis of infectious diseases -- Salivary markers in systemic and oral cancer -- Saliva in sport sciences -- Salivary biomarkers in welfare studies -- The future of saliva as an analytical sample.
    Abstract: Saliva as a unique sample for health assessment is gaining attention among researchers of different fields in the last 20 years; being reflected in an impressive increase in the number of papers published studying saliva from different biological aspects in human and veterinary species. Once deemed merely a digestive juice is now considered a biological fluid capable of communicating information about physiopathological processes occurring in organisms, since saliva has been shown to contain molecular and bacterial compounds that can change in response to local and systemic pathologies. Furthermore, the interest of saliva as a diagnostic, prognostic and monitoring biofluid is forced by its non-invasive nature being of easy and inexpensive sampling, involving only minimal discomfort and allowing the collection of multiple/repeated specimens at anytime, anywhere and without need for specialized staff. In this contributed volume, the authors bring together, summarize and reflect the generated knowledge about saliva as a source of biomarkers for health and welfare evaluation in humans and animal models. This volume also highlights the importance of confounding factors, such as sampling methods, flow, total protein content, contamination, or storage. This book will serve as a manual for graduates, practitioners and researchers by providing general ideas about the possibilities and utilities of saliva in clinical practice or investigation, and indicating the main cautions each should have in mind before saliva usage.
    Type of Medium: Online Resource
    Pages: X, 326 p. 23 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030376819
    DDC: 612
    Language: English
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  • 3
    Keywords: Human physiology. ; Medicine Research. ; Biology Research. ; Proteins . ; Biological transport. ; Cell membranes. ; Human Physiology. ; Biomedical Research. ; Protein Biochemistry. ; Membrane Trafficking.
    Description / Table of Contents: 1. Organoids as a Model for Intestinal Ion Transport Physiology -- 2. Secretory Diarrhea -- 3. Role of the Epithelium in Diseases of the Intestine -- 4. Diseases of the Pancreas Involving Channels/Transporters -- 5. Fundamentals of Ion Transport across Human Sweat Gland in Health and Disease -- 6. Transporters in the Lactating Mammary Epithelium -- 7. Lipid Transport Across the Mammary Gland -- 8. Ion Transport across Inner Ear Epithelia -- 9. Regulation of Ion Transport through Retinal Pigment Epithelium: Impact in Retinal Degeneration -- 10. Ion Transport in the Choroid Plexus Epithelium -- 11. Transport Functions of Ectoderm Epithelial Cells Forming Dental Enamel. .
    Abstract: This book discusses the unique ion channels and transporters found within the epithelial tissues of various organs, including the kidney, intestine, pancreas and respiratory tract. Authors focus on demonstrating the crucial roles that each of these channels and transporters play in transepithelial ion and fluid transport across epithelia, as well as in maintaining homeostasis. It allows readers to gain an understanding of the fundamentals of ion transport, in terms of function, modelling, regulation, trafficking, structure and pharmacology. This is the second of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on a wide array of epithelial tissues and the use of organoids to study epithelial function. Furthermore, clinical researchers and basic scientists from various fields provide a medical perspective on the physiology of a number of tissues and organs of the body including the pancreas, intestine, sweat glands, mammary gland, inner ear epithelia, retinal pigment epithelia of the eye, choroid plexus, and the ectodermal epithelia in dental enamel formation. This volume aims to ‘round out’ the reader’s journey from basic science to the laboratory bench and clinical management of molecular diseases, making Volume 2 a must-read for students and scientists in the field of physiology, as well as for clinicians.
    Type of Medium: Online Resource
    Pages: XIX, 382 p. 77 illus., 62 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030553104
    Series Statement: Physiology in Health and Disease,
    DDC: 612
    Language: English
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  • 4
    Keywords: Human physiology. ; Medicine Research. ; Biology Research. ; Cytology. ; Physiology. ; Human Physiology. ; Biomedical Research. ; Cell Biology. ; Physiology.
    Description / Table of Contents: Preface -- Chapter 1. Transcriptomics of the carotid body (Audrys G. Pauza, David Murphy and Julian F. R. Paton) -- Chapter 2. The adult carotid body: a germinal niche at the service of physiology (Ricardo Pardal) -- Chapter 3. Evidences that sympathetic overactivity and neurogenic hypertension correlate with changes in the respiratory pattern in rodent models of experimental hypoxia (Benedito H. Machado) -- Chapter 4. Control of arterial hypertension by the AhR blocker CH-223191: a chronopharmacological study in chronic intermittent hypoxia conditions (António B. Pimpão, Cátia Sousa, Maria J. Correia, Nuno R. Coelho, Emília Monteiro, António F. Melo Júnior and Sofia A. Pereira) -- Chapter 5. Three days of chronic intermittent hypoxia induces β1-adrenoceptor dependent increases in left ventricular contractility (Anthony L. Marullo, Eric F. Lucking, Daniel Pender, Pardeep Dhaliwal and Ken D. O’Halloran) -- Chapter 6. The beneficial effect of the blockade of stim-activated TRPC-ORAI channels on vascular remodeling and pulmonary hypertension inducedby intermittent hypoxia is independent of oxidative stress (Rodrigo Iturriaga and Sebastián Castillo-Galán) -- Chapter 7. Intermittent hypoxia and weight loss: insights into etiology of the sleep apnea phenotype (Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Loralie Guay, Vincent Joseph, Natalie J Michael and Richard Kinkead) -- Chapter 8. Effects of gestational intermittent hypoxia on placental morphology andfetal development in a murine model of sleep apnea (Esther Valverde-Pérez, Jesús Prieto-Lloret, Elvira Gonzalez-Obeso, María I. Cabero, Maria L. Nieto, Marta I. Pablos, Ana Obeso, Angela Gomez-Niño, Rosa M. Cárdaba-García, Asunción Rocher and Elena Olea) -- Chapter 9. Ventilatory effects of acute intermittent hypoxia in conscious dystrophic mice (Michael N. Maxwell, Anthony L. Marullo, Aoife D. Slyne, Eric F. Lucking and Ken D. O’Halloran) -- Chapter 10. Intermittent hypoxia and diet-induced obesity on the intestinal wall morphology in a murine model of sleep apnoea (Esther Valverde-Pérez, Elena Olea, Ana Obeso, Jesús Prieto-Lloret, Asunción Rocher and Elvira Gonzalez-Obeso) -- Chapter 11. Enhanced peripheral chemoreflex drive is associated with cardiorespiratory disorders in mice with coronary heart disease (Liena Bravo, Katherin V. Pereyra, Hugo S. Diaz, Mariajosé Flores, Karla G. Schwarz, Camilo Toledo, Esteban Díaz-Jara, Leticia González, Marcelo E. Andia and Rodrigo Del Rio) -- Chapter 12. Role of peripheral chemoreceptors on enhanced central chemoreflex drive in non-ischemic heart failure (Katherin Pereyra, Esteban Díaz-Jara, Paulina Arias, Liena Bravo, Camilo Toledo, Karla Schwarz and Rodrigo Del Rio) -- Chapter 13. Effect of carotid body denervation on systemic endothelial function in a diabetic animal model (Marlene D. Cabral, Fátima O. Martins, Inês B. Martins, Bernardete F. Melo, Joana F. Sacramento, Silvia V. Conde and Jesus Prieto-Lloret) -- Chapter 14. Contribution of carotid bodies on pulmonary function during normoxia and acute hypoxia (Karla G. Schwarz, Maríajose Flores, Nicolas Voituron and Rodrigo Del Rio) -- Chapter 15. Increased abdominal perimeter differently affect respiratory function in men and women (Joana F. Sacramento, Iolanda Caires, Maria P. Guarino, Maria J. Ribeiro, João C. P. Santiago, Ana T. Timóteo, Mafalda Selas, Miguel Mota-Carmo and Silvia V. Conde) -- Chapter 16. Carotid body resection prevents short-term spatial memory decline in prediabetic rats without changing insulin signaling in the hippocampus and prefrontal cortex (Adriana M. Capucho, Ana Chegão, Fátima O. Martins, Bernardete F. Melo, Natália Madeira, Joana F. Sacramento, Rosalina Fonseca, Hugo Vicente Miranda and Sílvia V. Conde) -- Chapter 17. Constitutive Expression of Hif2a Confers Acute O2 Sensitivity to Carotid Body Glomus Cells (Olalla Colinas, Alejandro Moreno-Domínguez, Patricia Ortega-Sáenz and José López-Barneo) -- Chapter 18. Of mice and men, and plethysmography systems: does LKB1 determine the set point of carotid body chemosensitivity and the hypoxic ventilatory response? (A. Mark Evans) -- Chapter 19. Analyzing angiotensin II receptor type 1 clustering in PC12 cells in response to hypoxia using direct stochastic optical reconstruction microscopy (dSTORM) (Hayyaf S. Aldossary, Daniel J. Nieves, Deirdre M Kavanagh, Dylan Owen, Clare J Ray, Prem Kumar, Andrew M. Coney and Andrew P. Holmes) -- Chapter 20. The Carotid Body “Tripartite Synapse”: Role of Gliotransmission (The Carotid Body “Tripartite Synapse”: Role of Gliotransmission) -- Chapter 21. Necroptosis contributes to reduced carotid body-mediated chemoreflex function during aging in mice (Esteban Díaz-Jara, Karla G Schwarz, Angelica Ríos-Gallardo, Camilo Toledo, Julio A Alcayaga, Felipe A Court and Rodrigo Del Rio) -- Chapter 22. Chronic metformin administration does not alter carotid sinus nerve activity in control rats (Joana F. Sacramento, Bernardete F. Melo, Jesus Prieto-Lloret and Silvia V. Conde) -- Concluding remarks.
    Abstract: The book will contain reviews and brief research articles from the participants attending the International Society for Arterial Chemoreception (ISAC) meeting, to be held in Lisbon in Portugal in June/July 2020. Since ISAC was first established, almost 70 years ago, many advances in the classical field of arterial O2, CO2 and pH sensing have been achieved but the most impressive ones are probably related to the non-canonical roles of the carotid body, as its involvement in sympatho-mediated diseases. Over the recent years, the carotid body field has gained attention with the findings that carotid body dysfunction is associated with the development/maintenance of highly prevalent diseases from cardio-metabolic diseases to asthma. Knowing that most of the patients with these pathologies lack long-term disease control, it is imperative to define new pathophysiological mechanisms aiming to find new therapeutic targets for treatment and prevention. This book will cover a broad range of topics related, not only with the fundamental knowledge of the mechanisms related with the chemical sensing in the carotid body, but also with the adaptive and mal-adaptive responses of arterial chemoreceptors to O2-dependent and O2-independent mechanisms, namely with their impact on respiratory, cardiovascular, and metabolic homeostasis in healthy and disease conditions. This volume will be required text for all the researchers in the field of arterial chemoreceptors and will provide a valuable reference source for years to come.
    Type of Medium: Online Resource
    Pages: XIX, 210 p. 72 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031323713
    Series Statement: Advances in Experimental Medicine and Biology, 1427
    DDC: 612
    Language: English
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  • 5
    Keywords: Human physiology. ; Medicine Research. ; Biology Research. ; Proteins . ; Biological transport. ; Cell membranes. ; Human Physiology. ; Biomedical Research. ; Protein Biochemistry. ; Membrane Trafficking.
    Description / Table of Contents: 1. Techniques in Epithelial Transport -- 2. Understanding Transepithelial Current Measurements -- 3. Mathematical Modeling of Epithelial Ion Transport -- 4. Rationale of Epithelia Transport -- 5. Establishment of Epithelial Polarity -- 6. Molecular Mechanisms of Apical and Basolateral Sorting in Polarized Epithelial Cells -- 7. Membrane Protein Folding and Structure -- 8. Epithelial Ion Channel Folding and ER Associated Degradation (ERAD) -- 9. Fundamentals of Epithelial Cl- Transport -- 10. Fundamentals of Epithelial Na+ Absorption -- 11. Physiologic Influences of Transepithelial K+ Secretion -- 12. Volume Regulation in Epithelia -- 13. Fundamentals of Bicarbonate Secretion in Epithelia -- 14. Sexual Dimorphism of Epithelial Ion Channels -- 15. Non-coding RNA-Dependent Regulation of Channels/Transporters. .
    Abstract: This book discusses unique ion channels and transporters that are located within epithelial tissues of various organs including the kidney, intestine, pancreas and respiratory tract. As the authors show, these channels and transporters play crucial roles in transepithelial ion and fluid transport across epithelia and their contribution to maintaining homeostasis. Readers will be introduced to the fundamentals of ion transport in terms of function, modelling, regulation, structure and pharmacology. This is the first of three volumes highlighting the importance of epithelial ion channels and transporters in basic physiology and pathophysiology of human diseases. This volume focuses on basic fundamentals of epithelial transport physiology. There is a range of chapters dedicated to specific aspects of epithelial ion transport and cell function. Accordingly, the authors discuss techniques used to determine epithelial function, principles of epithelia transport, polarization of epithelial cells, mathematical modelling of epithelial ion transport, protein folding of ion channels, degradation epithelial ion channels, fundamentals of epithelial sodium, potassium and chloride transport, fundamentals of bicarbonate secretion, volume regulation, and microRNA regulation of epithelial channels and transporters. Given its scope, Volume 1 offers a valuable resource for physiology students, scientists and clinicians alike. .
    Type of Medium: Online Resource
    Pages: XIX, 563 p. 106 illus., 71 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030527808
    Series Statement: Physiology in Health and Disease,
    DDC: 612
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Human physiology. ; Internal medicine. ; Nutrition   . ; Surgery. ; Medicine Research. ; Biology Research. ; Human Physiology. ; Internal Medicine. ; Nutrition. ; Surgery. ; Biomedical Research.
    Description / Table of Contents: Introduction to Obesity and Diabetes– The windows of opportunity -- Nutrition transition and obesity trends in Argentina within the Latin American context -- Challenges and Economic Burden of Diabetes in Africa -- Brown adipose tissue in obesity and diabetes -- White and Brown Adipose Tissue in Obesity and Diabetes -- microRNAs in obesity and metabolic diseases -- From Adipogenic Viruses to Anti-Diabetic Drug: A Translational Journey -- Genetic profiles in the obese population -- The Upstream Environment for the Obesity Epidemic -- Inflammation and its role in obesity-related complications -- Cross talk between adipose tissue, macrophages and other immune cells: Development of obesity and inflammation-induced metabolic diseases -- Diabetes forecasts and statistics for the coming decades -- Pancreatic islets of Langerhans: adapting cell and molecular biology to changes of metabolism -- Targeting advanced glycation end products (esRAGE and sRAGE) for obesity, diabetes and its associated complications -- Anti-incretin effect: a missing link between obesity, diabetes and metabolic surgery -- An update on Mendelian forms of obesity and their personalized treatments -- The Genetic Basis of Diabetic Kidney Disease -- Epigenetics and chronic inflammation: Role in early detection of type 2 diabetes -- Salivary and Urinary Metabolome in Pediatric Obesity and Metabolic Syndrome -- State-of-the-Art Metabolomics Investigations of Type 2 Diabetes -- The gut microbiome and type 2 diabetes mellitus -- Immunotherapeutic Approach to the Treatment and Prevention of Obesity -- Metabolic Syndrome Update -- Non-alcoholic fatty liver disease: a global public health issue -- Non-Alcoholic Fatty Pancreatic Disease (NAFPD) -- Normal weight obesity – A hidden pandemic -- Obesity in Children/Adolescents and Obesity-Related Comorbidities -- Obesity and cancer: linked molecular mechanisms -- Cognitive impairment in obesity and diabetes -- Metabolic pathways underlying neuropsychiatric disorders and obesity -- Heart failure and the obesity paradox -- Inflammatory mechanisms in diabetic kidney disease -- The epidemiology of the diabetes - depression comorbidity in Brazil -inequality and interaction -- Contribution of Hyperglycemia and Unhealthy Diet to Cardiovascular Mortality -- Gestational Diabetes Mellitus -- Update on Gestational Diabetes -- Vascular complications in type 2 diabetes -- What We Know and Don’t about High-Intensity Sweeteners -- Personalised Molecular Feedback for Weight Loss -- Diabetes and Obesity in the Child and Adolescent: Guidelines and Challenges -- Type 2 diabetes – an unresolved disease -- Glucose control in the ICU -- Continuous glucose monitors as wearable lifestyle behavior change tools in obesity and diabetes -- Endoscopic techniques for obesity and diabetes -- Bariatric embolization: a possible non-surgical option for weight reduction -- Progress in noninvasive beta-cell mass imaging -- Cancer staging with 18F-FDG PET/CT in hyperglycemic patients -- Pancreatic Islet Transplantation: A Surgical Approach to Type 1 Diabetes Treatment -- Pancreatic Transplantation in Diabetes: Indications, Contraindications and Perspectives. -Pharmacotherapy of Type 2 Diabetes -- GLP1-Receptor Agonists in Diabetes: Drugs, General Effects, and Cardiovascular Impact -- Diabetes and treatments -- Treatment of Diabetes and Heart Failure -- Cardiovascular impact of newer diabetes medications -- Pathogenesis and Molecular Targets in treatment of Diabetic Wounds -- Efficiency in public health through the promotion of Diabetes Day Hospitals: a regional proposal -- Surgical options in obesity and diabetes -- One anastomosis gastric bypass in the treatment of obesity: effects on body weight and the metabolome -- Robotic bariatric surgery -- The Role of Obesity and Bariatric Surgery in the Management of Knee and Hip Osteoarthritis -- Relapse of diabetes after metabolic/bariatric surgery -- Malnutrition in Obesity -- Sugar-Sweetened Beverage Taxes: Origins, Mechanisms, and Current Worldwide Status -- Mobile Health Interventions for Weight Management in Overweight and Obese Populations -- Biomarkers and Machine Learning Applications in Obesity -- Current approaches in diabetes mellitus prediction: applications of machine learning and emerging biomarkers -- Polycystic ovary syndrome and sarcopenic obesity -- Drug Pipeline for Obesity Therapy -- MC4R as a Target for Pharmacotherapeutic Treatment of Obesity and Type-2 diabetes -- Nanotechnology: Can it be a crusader in diabesity? -- Old and new anti-obesity devices for medical, surgical, and endoscopical use -- Electroceutical approaches for gastroparesis -- Useful Online Resources Hosting Information on Obesity and Diabetes.
    Abstract: Now in its second edition, this comprehensive handbook provides a state-of-the-art overview of recent advances in drug and non-drug therapies for obesity and diabetes. It also addresses major comorbidities, covering topics such as, cardiovascular diseases, renal and neuropsychiatric disorders, appetite control and micro RNAs. Special attention is also devoted to pediatric care, including the latest recommendations for therapy and prevention. Obesity and type 2 diabetes are among the top global health-care budget concerns worldwide and impact professional practice at all levels: in hospitals, clinics and physicians’ offices alike. They prominently feature in headlines, and virtually no family, community or country is exempt from their protean, deleterious consequences. Furthermore, given the multiple intersections in their pathways, they often go hand in hand. The good news is that scientific advances in all fields, including genomics, metabolomics, lipidomics and microbiomics, are increasing our understanding of these two disease areas. At the same time, artificial intelligence, machine learning, mobile health and advanced implantable and external devices are rendering prevention and management more available, safe and cost-effective. In addition, bariatric and metabolic surgery has evolved from a niche specialty to an officially endorsed option for several modalities of obesity and diabetes. This book presents the latest lifestyle, pharmacological, surgical and non-surgical treatment options, including endoscopic intervention and cell therapy. Objectively reviewing natural and artificial sweeteners and critically examining issues such as public health initiatives, government mandated taxes for unhealthy foods and environmental planning, no stone is left unturned in gathering the latest practical information. As such, the book will appeal to seasoned specialists, as well as students and healthcare professionals in training.
    Type of Medium: Online Resource
    Pages: XV, 994 p. 176 illus., 158 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030533700
    DDC: 612
    Language: English
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