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  • Books  (159)
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  • Cham :Springer International Publishing :  (159)
  • Bremerhaven : Alfred-Wegener-Inst. für Polar- und Meeresforschung
  • University of Virginia Library
  • Wabern : Federal Office of Topography, Swiss Geological Survey
  • 610.72  (104)
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  • Books  (159)
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  • 1
    Keywords: Medicine Research. ; Biology Research. ; Cardiovascular system. ; Physiology. ; Cardiology. ; Clinical biochemistry. ; Biomedical Research. ; Cardiovascular Physiology. ; Cardiology. ; Medical Biochemistry.
    Description / Table of Contents: Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure.
    Abstract: This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.
    Type of Medium: Online Resource
    Pages: XVIII, 452 p. 71 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031149528
    Series Statement: Advances in Biochemistry in Health and Disease, 24
    DDC: 610.72
    Language: English
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  • 2
    Keywords: Medicine Research. ; Biology Research. ; Medical education. ; Anatomy. ; Virtual reality. ; Augmented reality. ; Biomedical Research. ; Medical Education. ; Anatomy. ; Virtual and Augmented Reality.
    Description / Table of Contents: Chapter 1. Pandemic-Era Digital Education: Insights from an Undergraduate Medical Programme -- Chapter 2. Use of Lt Systems in Large Class Lab Delivery -- Chapter 3. COVID-19 Adaptations for Biomedical Teaching and Assessment Within the Undergraduate Dental Curriculum -- Chapter 4. One Size Does Not Fit All in Remote Anatomy Teaching -- Chapter 5. From Lecture Halls to Zoom Links: How Can Educational Theory Help Us to Deliver Effective and Engaging Teaching in an Online Environment? -- Chapter 6. Collaborative, Two-Directional Live Streaming to Deliver Hands-on Dissection Experience during the COVID-19 Lockdown -- Chapter 7. Livestreaming Can Augment the Observation of Veterinary Post-mortem Examinations -- Chapter 8. Virtual Reality for Anatomy and Surgical Teaching -- Chapter 9. Can Synchronous Online Near-Peer Teaching Offer the Same Benefits as the Face-to-Face Version When Used in Clinical Neuroanatomy Education? -- Chapter 10. COVID-19 Adaptations with Virtual Microscopy -- Chapter 11. The Challenges of Visualisation During Delivery and Assessment of Clinical Teaching Under COVID-19: A Reflective Account of Problem Solving -- Chapter 12. Not for Room 101.
    Abstract: This book focuses on the challenges to biomedical education posed by the lockdowns and restrictions to on campus teaching brought about by the COVID-19 pandemic and highlights the tools and digital visualization technologies that have been successfully developed and used for remote teaching. Biomedical education for science, medical, dental and allied health professionals relies on teaching visual and tactile knowledge using practice-based approaches. This has been delivered for decades via on-campus lectures, workshops and laboratories, teaching practical skills as well as fundamental knowledge and understanding. However, the arrival of the COVID-19 pandemic meant that education across the globe had to pivot very quickly to be able to deliver these skills and knowledge in a predominantly online environment. This brought with it many challenges, as Higher Education staff, had to adapt to deliver these visual subjects remotely. This book addresses the challenges and solutions faced by Higher Education staff in teaching visual content in distance education. Chapters include literature reviews, original research, and pedagogical reflections for a wide range of biomedical subjects, degrees such as medicine, dentistry and veterinary sciences with examples from undergraduate and postgraduate settings. The goal of the book is to provide a compendium of expertise based on evidence gathered during the COVID-19 pandemic, as well as reflections on the challenges and lessons learned from this dramatic shift in teaching. It also presents new examples of best practices that have emerged from this experience to ensure that they are not lost as we return to on-campus learning in a new era of biomedical teaching. This book will be of interest to anyone looking for a helpful reference point when designing online or blended teaching for visual practice-based subjects.
    Type of Medium: Online Resource
    Pages: X, 228 p. 56 illus., 52 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031171352
    Series Statement: Advances in Experimental Medicine and Biology, 1397
    DDC: 610.72
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biochemical markers. ; Proteins. ; Metabolism. ; Genomics. ; Biomarkers. ; Proteins. ; Metabolism. ; Genomics.
    Description / Table of Contents: Chapter 1. The COVID-19 Pandemic: SARS-CoV-2 Structure, Infection, Transmission, Symptomology and Variants of Concern -- Chapter 2. Long-term Vaccination and Treatment Strategies for COVID-19 Disease and Future Coronavirus Pandemics -- Chapter 3. Consequences of the Lockdown - Domestic Violence during the COVID-19 Pandemic -- Chapter 4. Psychological distress impact of Coronavirus disease (COVID-19) outbreak on three continents: A systematic review and meta-analysis -- Chapter 5. A Molecular Biomarker-based Triage Approach for Targeted Treatment of Post-COVID-19 Syndrome Patients with Persistent Neurological or Neuropsychiatric Symptoms -- Chapter 6. Genetic Associations with Coronavirus Susceptibility and Disease Severity -- Chapter 7. COVID Diagnostics: from Molecules to Omics -- Chapter 8. Assessing Biomarkers in Viral Infection -- Chapter 9. Proteomic Investigation of COVID-19 Severity During the Tsunamis Second Wave in Mumbai -- Chapter 10. NMR-Metabolomics in COVID-19 Research -- Chapter 11. Potential Biomarkers of Mitochondrial Dysfunction Associated with COVID-19 Infection -- Chapter 12. Red Cell Distribution Width as a Prognostic Indicator for Mortality and ICU Admission in Patients with COVID-19 -- Chapter 13. Predicting the COVID-19 Patients Status using Chest CT Scan Findings: A Risk Assessment Model Based on Decision Tree Analysis -- Chapter 14. Inferring Recombination Events in SARS-CoV-2 Variants In Silico -- Chapter 15. Amplicon-based Nanopore Sequencing of Patients Infected by the SARS-CoV-2 Omicron (B.1.1.529) Variant in India -- Chapter 16. Perspectives on Rapid Antigen Tests for Downstream Validation and Development of Theranostics -- Chapter 17. Machine Learning and COVID-19: Lessons from SARS-CoV-2 -- Chapter 18. The Relationship between Psoriasis, COVID-19 Infection and Vaccination during Treatment of Patients -- Chapter 19. Immunogenicity of Inactivated SARS-CoV-2 Vaccine (BBIBP-CorV; Sinopharm) and Short-term Clinical Outcomes in Vaccinated Solid Organ Transplant Recipients: A Prospective Cohort Study -- Chapter 20. Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective -- Chapter 21. Antiviral Mechanisms of Curcumin and its Derivatives in Prevention and Treatment of COVID-19: A review -- Chapter 22. Evaluation of Curcumin-Piperine Supplementation in COVID-19 Patients Admitted to the Intensive Care: A Double-Blind, Randomized Controlled Trial -- Chapter 23. Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases of COVID-19: A Hypothetical Approach -- Chapter 24. The Potential Effect of Royal Jelly on Biomarkers Related to COVID-19 Infection and Severe Progression -- Chapter 25. Statins: Beneficial Effects in Treatment of COVID-19 -- Chapter 26. Multiplex Immunoassay Approaches Using Luminex® xMAP® Technology for the Study of COVID-19 Disease -- Chapter 27. Rapid Detection of SARS-CoV-2 Variants of Concern by Genomic Surveillance Techniques.
    Abstract: The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.
    Type of Medium: Online Resource
    Pages: XI, 513 p. 87 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031280122
    Series Statement: Proteomics, Metabolomics, Interactomics and Systems Biology, 1412
    DDC: 610.72
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Neurology . ; Neurosciences. ; Nervous system Diseases. ; Biomedical Research. ; Neurology. ; Neuroscience. ; Neurological Disorders.
    Description / Table of Contents: PART I: Fundamental Aspects -- Chapter 1. Definition of Tremor -- Chapter 2. Membrane Mechanisms of Tremor -- Chapter 3 Advances in the Genetics of Human Tremor -- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor -- PART II:Tremor in Clinical Practice -- Chapter 5. Physiologic Tremor -- Chapter 6. Rest Tremor -- Chapter 7. Postural Tremors -- Chapter 8. Isometric Tremor -- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor -- Chapter 10. Cerebellar lesions and tremor -- Chapter 11. Orthostatic Tremor -- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders -- Chapter 13 Tremor in Childhood -- Chapter 14. Metabolic Causes of Tremor -- Chapter 15. Drug-Induced Tremor -- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis -- PART III: Assessment of tremor -- Chapter 17. Signal Processing -- Chapter 18. Diffusion imaging in Tremor -- Chapter 19. The role of the noradrenergic system in tremor pathogenesis -- Chapter 20. Metabolic Networks in Parkinson’s Disease -- PART IV: Therapies -- Chapter 21. Deep brain stimulation for tremor -- Chapter 22 Mechatronic Devices for Upper Limb Tremor.
    Abstract: Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment and provides practical information for daily management. This new edition is informed by the guidelines of the Tremor Task Force of the International Parkinson and Movement Disorders Society. New chapters include Classification of Tremors, Medically Induced Tremors, Resting State fMRI, and Gabaergic Pathways. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced.
    Type of Medium: Online Resource
    Pages: X, 558 p. 86 illus., 59 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031261282
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 610.72
    Language: English
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  • 5
    Keywords: Medicine Research. ; Biology Research. ; Vocational guidance. ; Career education. ; School management and organization. ; School administration. ; Biomedical Research. ; Career Counseling. ; Career Skills. ; Organization and Leadership.
    Description / Table of Contents: Part 1: Setting the scene -- Chapter 1: Life after Academia: Launching your Pharma/Biotech Career -- Chapter 2: Competences for Pharmacists -- Chapter 3: Job and Career Opportunities in the Pharmaceutical Industry: An Overview -- Part 2: Opportunities along the drug/product life cycle -- Chapter 4: Career Opportunities in Toxicology -- Chapter 5: Job Possibilities in Clinical Research -- Chapter 6: How to Get and Develop a Career in a Market Access Role in the Medical Devices Industry -- Chapter 7: Job Opportunities in Pharmaceutical Marketing -- Chapter 8: Working in Medical Affairs and Clinical Operations: Life-Changing Careers -- Chapter 9: The Role of Medical Science Liaison -- Chapter 10: Career Development for Physicians in the Biopharmaceutical Industry -- Part 3: Opportunities in Supportive Functions -- Chapter 11: Job and Career Opportunities in Regulatory Affairs/Science -- Chapter 12: Job Opportunities in Clinical Research Quality Assurance -- Chapter 13: Job Opportunities in Quality Assurance Related to Manufacturing of Medicinal Products -- Part 4: Other Opportunities in the Pharmaceutical and Biomedical Sector -- Chapter 14: Careers Perspective in a Science and Technology Park -- Chapter 15: To be or not to be: Entrepreneurship and Enterprise Creation as a Way to Innovate in Life Sciences -- Chapter 16: How to Become a Successful Hospital and Community Pharmacist -- Part 5: Practical tips and tricks -- Chapter 17: A Successful Career in the Life Sciences Industry: How to Write your Strongest Resumé and Ace that Interview -- Chapter 18: Skill Building for Career Advancement: Public Speaking and Networking -- Chapter 19: Training Opportunities for a Career in the Pharmaceutical and Biomedical Industry/Sector.
    Abstract: Written by dedicated and active professionals from different areas of the pharmaceutical, biomedical, and medtech sectors, this book provides information on job and career opportunities in various life sciences industries. It also contains useful tips to launch your own startup. The pharmaceutical, biomedical and medical technology sectors offer a wide range of employment opportunities to talented and motivated young graduates. However, many of these employment prospects are not well known to early career scientists, who concentrate primarily on the scientific and academic content of their fields of interest. The book is divided into five parts: Part 1 provides an academic perspective that focuses on the specific preparation required in the final years of study to embark on a successful career in the pharmaceutical and biomedical industries. In Part 2, industry experts discuss employment possibilities all along the drug or product life cycle, from discovery research and development to commercialisation. Part 3 follows, highlighting opportunities in support functions such as regulatory affairs or quality assurance. Part 4 focuses on additional opportunities in the wider biomedical sector, while Part 5 contains practical tips and training opportunities for entering the pharmaceutical and biomedical industries. In the epilogue, the authors reflect on this fascinating field and its career prospects. The book offers a multidisciplinary perspective on career opportunities in the pharmaceutical and biomedical industry to a wide range of students and young life scientists. .
    Type of Medium: Online Resource
    Pages: XXI, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031149115
    DDC: 610.72
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Clinical medicine Research. ; Epidemiology. ; Diseases Causes and theories of causation. ; Biomedical Research. ; Clinical Research. ; Epidemiology. ; Pathogenesis.
    Description / Table of Contents: 1. Introduction on Tuberculosis: Integrated Studies for a Complex Disease -- 2. Global Tuberculosis Epidemiology -- 3. Heterogeneity in Tuberculosis -- 4. The Unequivocal Relationship between Tuberculosis and Tobacco: Integration of Two Maladies -- 5. Relationship between Pre-existing Cancer and Tuberculosis -- 6. Laboratory Diagnosis of Tuberculosis -- 7. The Role of Diagnostic Microdevices in the Fight Against Tuberculosis -- 8. Immunodiagnostics of Tuberculosis: Recent Discoveries -- 9. Role of Bronchoscopy in Diagnostics and Treatment of Tuberculosis -- 10. Diagnosis of Childhood Tuberculosis in Low- and Middle-income Countries -- 11. Pediatric Tuberculosis: Current Evidence for Laboratory Diagnosis -- 12. A Multidisciplinary Approach Towards Finding and Treating All Tuberculosis Patients -- 13. Chemotherapy for Drug-Susceptible Tuberculosis -- 14. The Pharmacokinetic and Pharmacodynamic Properties of Antitubercular Medications -- 15. Immune Approaches In Tuberculosis Treatment -- 16. Inhalation Therapy in Pulmonary Tuberculosis -- 17. Role of Micronutrients in Tuberculosis Management -- 18. Drug Resistance in Tuberculosis: Mechanisms, Diagnosis, New Responses, and the Need for An Integrated Approach -- 19. Resistance in Tuberculosis: Molecular Mechanisms and Modulation -- 20. Personalized Tuberculosis Care for Drug-Resistant Tuberculosis -- 21. Important Targets and Inhibitors of Mycobacterium Tuberculosis -- 22. P-type ATPases: A Relevant Component in Mycobacterium tuberculosis Viability -- 23. The Challenges of Antitubercular Drug Discovery -- 24. Exploring Decaprenylphosphoryl-β-D-ribose 2’-Epimerase 1 (DprE1): A Target for Anti-Tubercular Drugs -- 25. Energy Pathways in Mycobacterium Tuberculosis -- 26. Drug Discovery for Non-Tuberculous Mycobacteria: Recent Updates -- 27. Challenges for Contact Tracing and Tuberculosis Preventive Therapy Scale-up -- 28. Exploring Problematizations Underlying Tuberculosis Control Strategies: A Cross-Country Analysis of India and Kenya -- 29. Challenges in Prevention and Management of Tuberculosis -- 30. Tuberculosis in Contacts and Healthcare Workers -- 31. Tuberculosis Among People Who Use Drugs: Multilevel Considerations for Prevention, Diagnosis, and Treatment -- 32. Anti-Tumor Necrosis Factor-α Antagonists and Tuberculosis -- 33. Breast Tuberculosis -- 34. Central Nervous System Tuberculosis: Pathogenesis, Diagnosis, and Management -- 35. Pleural Tuberculosis -- 36. Ocular Tuberculosis -- 37. Ocular Tuberculosis: Biomarkers for Risk Stratification -- 38. Bone and Joint Tuberculosis -- 39. Abdominal Tuberculosis: Pathogenesis, Clinical Features, and Diagnosis -- 40. Bovine Tuberculosis at The Interface of Cattle, Wildlife, and Humans -- 41. Evolution and Molecular Characteristics of Mycobacterium Tuberculosis and Mycobacterium Bovis -- 42. Animal Tuberculosis: Gross Lesions and Anatomopathological Diagnosis -- 43. Estimation of Microbial Mutation Rates in Tuberculosis Research -- 44. The Role of Epigenetics in the Development of Anti-Tuberculosis Drug Resistance -- 45. Multiomics Integration of Tuberculosis Pathogenesis -- 46. Lung Microbiome in Tuberculosis -- 47. The Correlation of Microbiota and Host Epigenome in Tuberculosis -- 48. The Pathogenesis and Progression of Sarcoidosis from The Standpoint of Tuberculosis -- 49. Tuberculosis: A Historical and Global Bioethical Perspective -- 50. The Problem of Tuberculosis: Myths, Stigma, and Mimics -- 51. Tuberculosis: Integrated Studies for a Complex Disease 2050.
    Abstract: Tuberculosis have been documented since antiquity and the search of the microbes that cause this disease started more than three hundred years ago. Nevertheless, tuberculosis remains an important global health issue, with millions of people affected per year in addition to millions that remain undiagnosed and untreated. Patients with tuberculosis face the full range of recurrence, reinfection, and resistance due to diagnostic, prophylactic, and therapeutic procedures that are not as effective as they should be. In addition, variability in susceptibility to tuberculosis pose a complex problem with numerous interrelated variables. This volume is devoted to the understanding of Tuberculosis focusing on its heterogeneity, its transmission, manifestations, related conditions, diagnosis, treatments, drug resistance and prevention.
    Type of Medium: Online Resource
    Pages: XXIV, 1116 p. 363 illus., 239 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031159558
    Series Statement: Integrated Science, 11
    DDC: 610.72
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Public health. ; Epidemiology. ; Medical policy. ; Medicine, Preventive. ; Health promotion. ; Biomedical Research. ; Public Health. ; Epidemiology. ; Health Policy. ; Health Promotion and Disease Prevention.
    Description / Table of Contents: Introduction on Integrated Science of Global Epidemics -- Emerging Viral Infections in Human Population -- One Health as An Integrated Approach: Perspectives from Public Services for Mitigation of Future Epidemics -- Multipronged Approach to Combat COVID-19: Lessons from Previous Pandemics for the Future -- Response to Disease Outbreaks in Africa: A Call to Build Resilient Health Systems -- Navigating Global Public Influenza Surveillance Systems for Reliable Forecasting -- Three Respiratory Syndrome Epidemics (SARS, MERS, COVID-19) in Two Decades: Clinical Epidemiological Considerations -- Epidemic in Complex Networks and Some Ideas About the Impact of Isolation Strategies in the Context of the COVID-19 Pandemic -- Optimal Control: Application and Applicability in Times of Pandemics -- Analysis of A COVID-19 Model Implementing SocialDistancing as An Optimal Control Strategy -- Impact of Policy Implementations on the Propagation of COVID-19 Before Vaccine -- Environmental Factors Associated with Global Pandemic Transmission and Morbidity -- Urbanization and the Epidemiology of Infectious Diseases: Towards the Social Framing of Global Responses -- Pandemics and Mass Casualties: Cornerstones of Management -- Social Marketing Contributions to Mitigate Global Epidemics -- The Significance of Super Intelligence of Artificial Intelligence Agencies in the Social Savageries of COVID-19: An Appraisal -- Integration of Sex and Gender Approaches in National Ethics Committees’ Mandate to Appraise COVID-19 Research Protocols: Lessons from West Africa -- Psychology, Law, Ethics, Telehealth, and the Global Pandemic -- Physical Inactivity, Sedentarism, and Low Fitness: A Worldwide Pandemic for Public Health -- The Global Epidemic of Diabesity: Are We Heading for An Unsustainable Future? -- Nutrition, Function, and Quality of Life in Older Adults Socially Isolated Due to the COVID-19 Pandemic: A Focus on Telehealth Interventions -- Africa’s Response to Pandemics -- Vaccine Hesitancy and Refusal: History, Causes, Mitigation Strategies -- Vaccine Compliance versus Trust in a Pandemic -- Child Development in A Crisis: A Pandemic -- HIV/AIDS Problems and Policies in Adolescent Population -- Addressing Needs of Foreign Schoolchildren to Combat a Global Epidemic of Dengue Virus Infection: Transnational and Trans-sectoral Initiatives -- Integrated Science of Global Epidemics 2050.
    Abstract: The “Integrated Science of Global Epidemics” is the new proposed volume of Integrated Science Book series, aiming to publish the results of the most updated ideas and reviews on Global Epidemics. The whole world is suffering from complex problems, border less problems and global solution should be developed. The Integrated Science of Global Epidemics aims to highlight the combination of different disciplines, including formal sciences, physical-chemical sciences and engineering, biological sciences, medical sciences, and social sciences, to deal with complex problems such as global epidemics. This contributed volume could be used as guidelines for the entire scientific community and policy makers to successfully face these global threats. Chapter 27 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 623 p. 170 illus., 144 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031177781
    Series Statement: Integrated Science, 14
    DDC: 610.72
    Language: English
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  • 8
    Keywords: Medicine Research. ; Biology Research. ; Neurology . ; Internal medicine. ; Immunology. ; Biomedical Research. ; Biomedical Research. ; Neurology. ; Internal Medicine. ; Immunology.
    Description / Table of Contents: Chapter 1. Malignant Glioma -- Chapter 2. Benign Glioma -- Chapter3. Meningioma and Other Meningeal Tumors -- Chapter4. Epondymomas in Pediatric and Adults -- Chapter5. Medulloblastomas in Pediatric and Adults -- Chapter6. Benign and Malignant Tumors of The Pineal Region -- Chapter7. The Tumors of Choroid Plexus and Other Ventricular Tumors -- Chapter8. Embryonal Tumors of The Central Nervous System with Multilayered Rosettes and Atypical Teratoid/Rhabdoid Tumors -- Chapter9. Glioneuronal and Neuronal Tumors of the Central Nervous System -- Chapter10. Benign and Malignant Tumors of the Pituitary Gland -- Chapter11. Craniopharyngioma in Pediatric and Adults -- Chapter12. Schwannomas of Brain and Spinal Cord -- Chapter13. Other Nerve-Sheet Tumors of Brain and Spinal Cord -- Chapter14. Hemangioblastomas and Other Vascular Originating Tumors of Brain or Spinal Cord -- Chapter15. Brain and Spinal Cord Tumors of Embryonic Origin -- Chapter16. Brain and Spinal Tumors Originating from the Germ Line Cells -- Chapter17. Benign Brain and Spinal Tumors Originating from Bone or Cartilage -- Chapter18. Benign Spinal Tumors -- Chapter19. Other Less Prevalent Tumors of the Central Nervous System -- Chapter20. Brain and/or Spinal Cord Tumors Accompanied with Other Diseases or Syndromes -- Chapter21. Psychological and Psychiatric Aspects of Brain and Spinal Cord Tumors -- Chapter22. A Brief Explanation on Surgical Approaches for Treatment of Different Brain Tumors.
    Abstract: This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5–9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences. The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.
    Type of Medium: Online Resource
    Pages: XXIX, 739 p. 287 illus., 159 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031237058
    Series Statement: Advances in Experimental Medicine and Biology, 1405
    DDC: 610.72
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical sciences. ; Drug development. ; Pharmacology. ; Genetics Research. ; Clinical medicine Research. ; Biochemical markers. ; Translational Research. ; Preclinical Research. ; Pharmacology. ; Genetics Research. ; Clinical Research. ; Biomarkers.
    Description / Table of Contents: MATRICS – an update -- Cognitive [Computational] Neuroscience Test Reliability and Clinical Applications for Serious mental illness (CNTRaCS) Consortium: Progress and Future Directions -- Attention in Schizophrenia -- Perceptual Functioning -- Episodic Memory and Schizophrenia: From Characterization of Relational Memory Impairments to Neuroimaging Biomarkers -- Working Memory in People with Schizophrenia -- "Targeting Frontal Gamma Activity with Neurofeedback to Improve Working Memory in Schizophrenia" -- Cognitive Dysfunction as a Risk Factor for Psychosis -- Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity -- Developmental manipulation-induced changes in cognitive functioning -- Genetic underpinnings of cognitive dysfunction in schizophrenia -- Primate models of cognitive deficit re schizophrenia -- Olfactory cognitive deficits -- Medication/Anticholinergic burden impacting cognition in schizophrenia An Update on Treatment of Cognitive Impairment Associated with Schizophrenia -- Cannabis & cognition -- Sex/gender differences -- Neuroinflammation linked to cognition.
    Abstract: This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia. The work on cognition in schizophrenia from the past 20 years is highlighted, and emphasis throughout the book is placed on utilizing the Research Domain Criterion framework. Thus, the book also covers animals work relevant to schizophrenia that assesses behaviors utilizing the same framework, enabling mechanistic studies and highlighting potential biomarkers of function. The book also includes important areas of research in the field of cognitive function in schizophrenia that have received less attention, such as cognitive side-effects of current treatments and olfactory-based cognition. Altogether, the book provides a translational perspective of the most-up-to-date research on cognition in schizophrenia to-date, but with identification of novel directions for research initiatives.
    Type of Medium: Online Resource
    Pages: XII, 497 p. 70 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031264412
    Series Statement: Current Topics in Behavioral Neurosciences, 63
    DDC: 610.72
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Genomics. ; Cancer. ; Immunology. ; Nutrition   . ; Physiology. ; Biomedical Research. ; Genomics. ; Cancers. ; Immunology. ; Nutrition. ; Physiology.
    Description / Table of Contents: 1. The human genome and its variations -- 2. Gene expression and chromatin -- 3. The basal transcriptional machinery -- 4. Transcription factors and signal transduction -- 5. A key transcription factor family: Nuclear receptors -- 6. DNA methylation -- 7. Histone modifications -- 8. Chromatin remodeling and organization -- 9. Regulatory impact of non-coding RNA -- 10. Genome-wide principles of gene regulation -- 11. Epigenetics in development -- 12. Epigenetics and aging -- 13. Epigenetics and disease -- 14. Cells and tissues of the immune system -- 15. Innate immunity and inflammation -- 16. Adaptive immunity and antigen receptor diversity -- 17. B cell immunity: BCRs, antibodies and their effector functions -- 18. Antigen-presenting cells and MHCs -- 19. T cell immunity: TCRs and their effector functions -- 20. Immunity to bacterial pathogens and the microbiome -- 21. Immunity to viral pathogens and the virome -- 22. Tolerance and transplantation immunology -- 23. Immunological hypersensitivities: Allergy and autoimmunity -- 24. Introduction to cancer -- 25. Oncogenes, signal transduction and the hallmarks of cancer -- 26 Tumor suppressor genes and cell fate control -- 27. Multistep tumorigenesis and genome instability -- 28. Cancer genomics -- 29. Cancer epigenomics.-30. Aging and cancer -- 31. Tumor microenvironment -- 32 Metastasis and cachexia -- 33. Cancer immunology -- 34 Architecture of cancer therapies -- 35 Nutrition and common diseases -- 36 Interference of the human genome with nutrients -- 37. Nutritional epigenetics, signaling and aging -- 38. Chronic inflammation and metabolic stress -- 39. Obesity -- 40. Insulin resistance and diabetes -- 41. Heart disease and the metabolic syndrome -- 42 Epigenetics, inflammation and disease.
    Abstract: The fascinating area of molecular medicine provides a molecular and cellular description of health and disease. Starting with the understanding of gene regulation and epigenetics, i.e., the interplay of transcription factors and chromatin, this book will provide an fundamental basis of nearly all processes in physiology, both in health as well as in most common disorders, such as cancer, diabetes as well as in autoimmune diseases. Most non-communicable human diseases have a genetic (= inherited) as well as an epigenetic component. The later one is based on our lifestyle choices and environmental exposures. Many common diseases, such as type 2 diabetes, can be explained only to some 20% via a genetic predisposition. We cannot change the genes that we are born with but we can take care of the remaining 80% being primarily based on our epigenome. Therefore, there is a high level of individual responsibility for staying healthy. Thus, not only biologists and biochemists should be aware of this topic, but all students of biomedical disciplines will benefit from being introduced into the concepts of molecular medicine. This will provide them with a good basis for their specialized disciplines of modern life science research. The book is subdivided into 42 chapters that are linked to a series of lecture courses in “Molecular Medicine and Genetics”, “Molecular Immunology”, “Cancer Biology” and “Nutrigenomics” that is given by one of us (C. Carlberg) in different forms since 2002 at the University of Eastern Finland in Kuopio. This book represents an updated version and fusion of the books textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8). “Molecular Immunology: How Science Works” (ISBN 978-3-030-XXX), “Cancer Biology: How Science Works” (ISBN 978-3-030-75699-4) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4). By combining basic understanding of cellular mechanism with clinical examples, the authors hope to make this textbook a personal experience. A glossary in the appendix will explain the major specialist’s terms.
    Type of Medium: Online Resource
    Pages: XXXIV, 700 p. 301 illus., 300 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031271335
    DDC: 610.72
    Language: English
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  • 11
    Keywords: Geographic information systems. ; Human geography. ; Environmental management. ; Geographical Information System. ; Human Geography. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Interdisciplinarity, GIScience, and Socio-environmental Research in Latin America -- Chapter 2. Using Spatial Time-series and Field Data to Understand Cultural Drivers of Land Change: Connecting Land Conflict and Land Change in Eastern Amazonia -- Chapter 3. Crossing Boundaries: Transboundary Geographic Information in the Amazon Borderlands of Peru and Brazil -- Chapter 4. Territorial Implications of Economic Diversification in the Waorani Ancestral Lands -- Chapter 5. New Insights on Water Quality and Land Use Dynamics in the Napo Region of Western Amazonia -- Chapter 6. From Mapping to Guiding: An Emergent Framework for the Multiple Uses of Remote Sensing and GIScience in Socio-Environmental Research in the Peruvian Andes -- Chapter 7. The Use of Remote Sensing in Air Pollution Control and Public Health -- Chapter 8. Human-environmental Interactions and their Impacts on Temperate Forests in the Exploradores Valley in Western Patagonia -- Chapter 9. El Chaltén, Argentine Patagonia: A successful Combination of Conservation and Tourism? -- Chapter 10. GIS Approaches to Environmental Justice in Mexico’s Oil and Gas Production Zones with Implications for Latin America -- Chapter 11. Contributions to Socio-Environmental Research through Participatory GIS in Archaeology -- Chapter 12. Comparing Volunteered Data Acquisition Methods on Informal Settlements in Mexico City and São Paulo: a Citizen Participation Ladder for VGI -- Chapter 13. CHALLENGES AND OPPORTUNITIES Interdisciplinary GIScience Research on Human-environment Dynamics in Latin America.
    Abstract: This contributed volume presents relevant examples of socio-environmental research that highlight the challenges and opportunities of using geotechnologies in interdisciplinary settings across the vast, culturally, and environmentally mega-diverse region known as Latin America. While remote sensing has been mostly used for mapping and monitoring physical features, geographic information systems open up opportunities for the integration of socio-economic and environmental data collected through individual and community-based surveys, in-situ measurements, and other participatory research techniques to offer additional analytically grounded power when evaluating socio-environmental processes that shape Latin American landscapes. The topics addressed in this book include deforestation and land degradation, borderlands dynamics, agriculture and agroecological systems, environmental conservation and development, public health, tourism, environmental justice, archeology, volunteered geography and urban planning, among others. The book is intended for academics, graduate and undergraduate classrooms, and general audiences with interest in Latin America and the socio-environmental issues that threaten the sustainability of the region and local communities. The book will also appeal to practitioners, managers, and policy makers interested in the application of geo-technologies and field-based research to address complex socio-environmental problems in the Global South. .
    Type of Medium: Online Resource
    Pages: XIX, 294 p. 78 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031226809
    Series Statement: The Latin American Studies Book Series,
    DDC: 910.285
    Language: English
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  • 12
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Biomedical Research. ; Biomedical Research. ; Biomedical Research. ; Medical Genetics.
    Description / Table of Contents: Chaptre 1. Brain and Spinal Cord Tumors Among the Life-Threatening Health Problems: An Introduction -- Chaptre 2. Epidemiology of Brain and Spinal Cord Tumors -- Chaptre 3. The Role of Neuro-inflammation and Innate Immunity in Pathophysiology of Brain and Spinal Cord Tumors -- Chaptre 4. The Role of Cellular Immunity and Adaptive Immunity in Pathophysiology of Brain and Spinal Cord Tumors -- Chaptre 5. Immunotherapy as a New Therapeutic Approach for Brain and Spinal Cord Tumors -- Chaptre 6. Cell of Origin of Brain and Spinal Cord Tumors -- Chaptre 7. The Role of Bioinformatics and Imaging Models in Tumorigenesis and Treatment Response of Brain and Spinal Cord Neoplasms -- Chaptre 8. The Role of Epigenetics in Brain and Spinal Cord Tumors -- Chaptre 9. Stem Cells and Targeted Gene Therapy in Brain and Spinal Cord Tumors -- Chaptre 10. Nutrition and Diet: A Double-Edged Sword in Development and Treatment of Brain Tumors -- Chaptre 11. The Role of Nanotechnology in Brain Tumors -- Chaptre 12. The Role of Nanotechnology in Spinal Cord Tumors -- Chaptre 13. The Economic Burden of Malignant Brain Tumors.
    Abstract: Brain tumors comprise about 5–9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well. Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment. The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.
    Type of Medium: Online Resource
    Pages: XX, 231 p. 30 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031147326
    Series Statement: Advances in Experimental Medicine and Biology, 1394
    DDC: 610.72
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Drug delivery systems. ; Vaccines Biotechnology. ; Biomaterials. ; Immunotherapy. ; Biomedical Research. ; Drug Delivery. ; Biomaterials-Vaccines. ; Immunotherapy.
    Description / Table of Contents: Chapter 1 A short introduction to vaccines -- Chapter 2 Thermostability of vaccines -- Chapter 3 Drying technologies for vaccines -- Chapter 4 Aseptic spray drying technology -- Chapter 5 Design of experiment studies and scale-up -- Chapter 6 Applications of spray dried vaccines.-Chapter 7 Conclusions and future perspectives of spray-dried vaccines.
    Abstract: This book addresses the stabilization of vaccine powders by spray drying and provides an overview of the current state of the art on a laboratory and industrial scale. The book aims to familiarize readers with the advances in vaccine spray drying technology to understand its application potential better. In particular, the book addresses the design of aseptic spray dryers, parameters affecting the spray drying process, sterile powder processing, cleaning procedures, and powder filling. In addition, different drying technologies for the production of dry powder vaccines are compared to discuss the unique capabilities of spray drying as a particle technology for vaccines. Special attention is given to research studies on spray-dried vaccines published over the past 30 years, with key findings from laboratory research to clinical trials. Potential applications of spray-dried vaccines and routes of administration are presented in detail. Finally, an outlook is given on how close the aseptic spray-drying of vaccines is to the market and the challenges that need to be overcome to be commercially successful. The book's target audience is academics, researchers, vaccine developers, industry experts, students, and possibly funders, including government agencies, who are active in the field. In addition, the book is a reference source for those involved in the vaccine formulation and biopharmaceutical processing industry.
    Type of Medium: Online Resource
    Pages: XXIX, 589 p. 243 illus., 176 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031243233
    DDC: 610.72
    Language: English
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  • 14
    Keywords: Medicine Research. ; Biology Research. ; Radiology. ; Medical education. ; Anatomy. ; Biomedical Research. ; Radiology. ; Medical Education. ; Anatomy.
    Description / Table of Contents: Part I. Microscopy -- Chapter 1. Advances in Microscopy and Its Applications with Special Reference to Fluorescence Microscope: An Overview -- Chapter 2. Visualisation of Host-Pathogen Communication -- Chapter 3. A Review of Pathology and Analysis of Approaches to Easing Kidney Disease Impact: Host-Pathogen Communication and Biomedical Visualization Perspective -- Part II. Radiology and Patient Care -- Chapter 4. The Evolution of Equipment and Technology for Visualising the Larynx and Airway -- Chapter 5. The Impact of Technological Innovation on Dentistry -- Chapter 6. Advanced 3D Visualization and 3D Printing in Radiology -- Chapter 7. 3D Visualisation of the Spine -- Part III. Anatomy Education -- Chapter 8. Visualization in Anatomy Education -- Chapter 9. Visualizing Anatomy in Dental Morphology Education -- Chapter 10. Flashcards: The Preferred Online Game-Based Study Tool Self-Selected by Students to Review Medical Histology Image Content.
    Abstract: This book highlights the integration of science and imaging and demonstrates how we can teach and learn in a much more accessible, innovative, and engaging way using technology. This volume is particularly focused on three main themes: advanced microscopy, anatomy education, and radiology visualisation related to patient care. The chapters pertaining to advanced microscopy convey complex biomedical information by visual means. These chapters provide both an overview on the principles of microscopy and specific applications of microscopy that have led to groundbreaking discoveries. Chapters pertaining to education summarise the recent trends in teaching gross and microscopic anatomy and emphasise the creation and use of novel tools to support student learning. Lastly, the radiological visualisation segment dives into the history of radiographic imaging and highlights the profound effect technology has had on improving patient outcomes. This volume will be of particular interest to many; the scope of this book encompasses medicine, dentistry, allied health professions, biomedical sciences, anatomy and histology education, radiology, and microscopy. Students, researchers, educators, and clinicians will learn something new, be stimulated to ask innovative questions, and be inspired to continue the technological advancements pushing science forward. .
    Type of Medium: Online Resource
    Pages: XI, 224 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031264627
    Series Statement: Advances in Experimental Medicine and Biology, 1406
    DDC: 610.72
    Language: English
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  • 15
    Keywords: Medicine Research. ; Biology Research. ; Human physiology. ; Cancer. ; Cancer Treatment. ; Virology. ; Therapeutics. ; Biomedical Research. ; Human Physiology. ; Cancer Biology. ; Cancer Therapy. ; Virology. ; Therapeutics.
    Description / Table of Contents: 1. Implications of renin-angiotensin system in health and disease -- 2. Renin angiotensin system and aging -- 3. The interplay of the renin-angiotensin system and solid organ transplantation -- 4. Correlation between renin angiotensin system and infectious disease -- 5. Emerging contributions of endocrine pathophysiology in virus-related infectious disease -- 6. Understanding the renin-angiotensin system in coronavirus disease 2019 -- 7. Metabolomics approach in differentiating RAS responses in ARDS (Acute respiratory distress syndrome) and SAR-CoV-2 -- 8. A Comprehensive review of the impact of the renin angiotensin system in the liver, lung, infectious diseases and cancers -- 9. Application of biosensors for monitoring changes in renin angiotensin system (RAS) in cancers and lung diseases -- 10. Bioinformatics study on renin angiotensin in lung, and liver cancer using plant-based extracts -- 11. Role of renin-angiotensin system in the pathogenesis and progression of non-alcoholic fatty liver -- 12. The classical and nonclassical renin-angiotensin-aldosterone system in liver cirrhosis -- 13. Renin-angiotensin-aldosterone system role in organ fibrosis -- 14. Role of renin angiotensin-aldosterone system in kidney homeostasis -- 15. Renin-angiotensin system in chronic kidney disease: Implications in stroke outcome -- 16. The renin-angiotensin system and cancer -- 17. Renin-angiotensin system and cancer: From laboratory to clinics -- 18. Role of renin-angiotensin system in cancer cachexia -- 19. Renin angiotensin system activity in different cancers: Mechanistic insight and preclinical studies -- 20. The new dimension of the renin-angiotensin system in the hallmarks of cancer -- 21. Renin-angiotensin system in hematological malignancies -- 22. Renin angiotensin system (RAS): The common thread between cancer and heart failure -- 23. Renin-angiotensin system: a potential therapeutic target for colorectal cancer -- 24. Anticancer role of natural phenolic acids by targeting angiotensin-converting enzyme (ACE) -- 25. Angiotensin-(1-7): A Prospective Cancer Therapeutic.
    Abstract: This book of the series on “Advances in Biochemistry in Health and Disease” includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters. This book has been organized into three sections: (i) General Implications of RAS in human health and Infectious Diseases, (ii) Lung, Liver and Kidney Diseases, and (iii) Development of Cancer. Each chapter has discussed comprehensive knowledge regarding the molecular and cellular aspects of the role of RAS in the pathophysiology and pharmacotherapy of different disease processes. Biochemical mechanisms associated with angiotensin II type 1 and type II receptors, and angiotensin (1-7) MAS receptors for the occurrence of both harmful and beneficial effects of prolonged activation of RAS in different diseases have been outlined. It is noteworthy to point out that different chapter in this book were prepared by recognized global expertise in the area of inflammation, oxidative stress and signal transduction pathways to highlight the role of RAS in different diseases. It is our sincere hope that this book will be of great interest to both biomedical investigators and health professionals as well as graduate students and postdoctoral fellows all over the world.
    Type of Medium: Online Resource
    Pages: XX, 498 p. 70 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031236211
    Series Statement: Advances in Biochemistry in Health and Disease, 25
    DDC: 610.72
    Language: English
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  • 16
    Keywords: Medicine Research. ; Biology Research. ; Biophysics. ; Biomechanics. ; Immunology. ; Bones. ; Biomedical engineering. ; Biomedical Research. ; Biophysics. ; Biomechanics. ; Osteoimmunology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Preface (Brianne K. Connizzo, Lin Han, Robert L. Sah) -- Scientific Impact -- Chapter 1. Aggrecan and Hyaluronan: The infamous Cartilage Polyelectrolytes- Then and Now (Anna Plaas, Meghan Moran, John Sandy, Vincent Hascall) -- Chapter 2. Understanding the Influence of Local Physical Stimuli on Chondrocyte Behavior (Byumsu Ki, Lawrence J. Bonassar) -- Chapter 3. Multiscale In Silico Modeling of Cartilage Injuries (Rami K. Korhonen, Atte S.A. Eskelinen, Gustavo A. Orozco, Amir Esrafilian, Cristina Florea, and Petri Tanska) -- Chapter 4. In Vitro Models and Proteomics in Osteoarthritis Research (Martin Rydén, Patrik Önnerfjord) -- Chapter 5. Nanomechanics of Aggrecan: A New Perspective on Cartilage Biomechanics, Disease and Regeneration (Chao Wang, Elizabeth R. Kahle, Lin Han) -- Chapter 6. Computational Modelling for Managing Pathways to Cartilage Failure (Saeed Miramini, David W. Smith, Bruce S. Gardiner, Lihai Zhang) -- Chapter 7. Gene Delivery to Chondrocytes (Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De la Vega) -- Chapter 8. Mechanical Articular Cartilage Injury Models and Their Relevance in Advancing Therapeutic Strategies (Bodo Kurz, Melanie L Hart, Bernd Rolauffs) -- Chapter 9. Hip Osteoarthritis: Bench to Bedside Perspective (Young-Jo Kim) -- Chapter 10. Harnessing Growth Factor Interactions to Optimize Articular Cartilage Repair (Stephen B. Trippel) -- Personal Tributes -- Index.
    Abstract: This is an open access book. In honor of his 75th birthday, we reflect on the impact of the pioneering work of Alan Grodzinsky and his laboratory. This volume includes in-depth discussions of tissue electromechanics, mechanobiology and biomechanics, and matrix biology in addition to the latest advancements in understanding the pathogenesis, progression and treatment of osteoarthritis. Unique to this volume, we overview decades of groundbreaking research that set the stage for the latest efforts in the field, highlighting the legacy of one researcher and their trainees.
    Type of Medium: Online Resource
    Pages: XIV, 173 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031255885
    Series Statement: Advances in Experimental Medicine and Biology, 1402
    DDC: 610.72
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Lysine demethylation in pathogenesis -- Chapter 2. Targeting the LSD1/KDM1 Family of Lysine Demethylases in Cancer and Other Human Diseases -- Chapter 3. KDM2 demethylases as drug targets -- Chapter 4. Role of histone demethylase KDM3 (JMJD1) in transcriptional regulation and cancer progression -- Chapter 5. KDM4 demethylases as drug targets -- Chapter 6. KDM5 lysine demethylases in pathogenesis, from basic science discovery to the clinic -- Chapter 7. Context-dependent functions of lysine demethylases in physiology and disease -- Chapter 8. KDM7 demethylases as drug targets.
    Abstract: This book provides a comprehensive summary of our current knowledge on lysine demethylases, a class of epigenetic regulators. It takes the reader on an exciting journey spanning the past two decades, starting from the initial discovery and characterization of these enzymes and leading up to the development of their small molecule modulators. These modulators have shown promise in clinical trials and hold great potential to improve patient outcomes. The book captures the progress made in this field and highlights the significant advancements that have paved the way for potential therapeutic applications. The book covers a wide range of topics, spanning both basic biology and clinical implications associated with lysine demethylases. It offers a comprehensive historical and conceptual framework for the discovery and characterization of similar epigenetic enzymes or modulators. Chapter one serves as an introductory overview, providing insights into the general characteristics and functions of lysine demethylases. In subsequent chapters, specifically chapters two to eight, each major family of lysine demethylases is individually explored in depth. By providing in-depth insights into the functional aspects of these enzymes, the book allows readers to grasp their significance in regulating cellular processes and influencing pathogenesis. Moreover, the book goes beyond fundamental knowledge and also explores the development of diagnostic and therapeutic strategies related to lysine demethylases. It highlights the potential for utilizing these enzymes as therapeutic targets for the treatment of various diseases, including cancer and infectious diseases. Additionally, the book highlights future directions aimed at further unraveling the roles of lysine demethylases and translating these findings into the clinic.
    Type of Medium: Online Resource
    Pages: VII, 184 p. 35 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031381768
    Series Statement: Advances in Experimental Medicine and Biology, 1433
    DDC: 610.72
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Blockchains (Databases). ; Medical care. ; Medical Ethics. ; Medical policy. ; Biomedical Research. ; Blockchain. ; Health Care. ; Medical Ethics. ; Health Policy.
    Description / Table of Contents: 1. Introductory chapter: Early applications and evolution of blockchain implementations in medicine -- 2. Can Blockchain Technology Change Contemporary Medicine As It Is Currently Understood? -- 3. The Current State of Healthcare Information Exchange (HIE) and Proposing a Blockchain HIE Infrastructure -- 4. An amalgamation of blockchain and connected health for combating COVID-19 -- 5. Applications of Blockchain Technology in the COVID-19 Era. 6. Distributed Ledgers and Immunity Passports: The Intersection of Clinical Medicine and Digital Technology -- 7. Digital Identity, Computational Reliabilism, and the Future of IOMT: Epistemic Reasoning and The Role of Blockchain in Removing Human Tampering from Pharmacovigilance Decision Making -- 8. Potential implementations of blockchain technology in patient safety: A high-level overview -- 9. Blockchain in Medical Education -- 10. Blockchain in Education: Linking Competency Assessment with Credentialing -- 11. Optimizing Blockchain Technology in Academic Medicine -- 12. Distributed Research Networks -- 13. Use of Blockchain Technology for Implantable Medical Device Tracking -- 14. Application of Blockchain Technology in Healthcare Supply Chains.
    Abstract: Blockchain technology (BT) is quietly transforming the world, from financial infrastructure, to the internet-of-things, to healthcare applications. With increasing penetration of BT into various areas of our daily lives, the need arises for better awareness and greater knowledge about the capabilities, benefits, risks, and alternatives to distributed ledger applications. It is hoped that current book will be one of the pioneering collections focusing on blockchain implementations in the area of healthcare, with specific aim to present content in an easy-to-understand and readily accessible way for typical end-users of blockchain-based applications. There are important areas within the fabric of modern healthcare that stand to benefit from implementations of BT. These areas include electronic medical records, quality control, patient safety, finance, device tracking, biostamping/biocertification, redundant storage of critical data, health and liability insurance, medication utilization tracking (including opioid and antibiotic misuse), financial transactions, academics/education, asset tokenization, public health and pandemics, healthcare provider credentialing, and many other potential applications. The ultimate goal of the proposed book would be to provide an integrative, easy-to-understand, and comprehensive picture of the current state of blockchain use in healthcare while actively engaging the reader in a forward-looking, exploratory approach toward future developments in this space. To accomplish this goal, an expert panel of contributors has been assembled, featuring scholars from top global universities and think-tanks.
    Type of Medium: Online Resource
    Pages: VIII, 250 p. 33 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031145919
    Series Statement: Integrated Science, 10
    DDC: 610.72
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Measurement. ; Measuring instruments. ; Biophysics. ; Biomedical Research. ; Measurement Science and Instrumentation. ; Biophysics.
    Description / Table of Contents: 1. Principles of molecular recognition -- 2. Theoretical Aspects -- 3. Molecular Recognition Units in Sensor Constructions -- 4. Binding blocks and Interfaces Designed for Sensing -- 5. Probing the properties of continuous media and interfaces -- 6. Detection of Ions and Low-molecular Targets -- 7. Detection of Biological Macromolecules and Recognition of harmful microbes -- 8. Sensing Inside the Living Cells -- 9. Ex-vivo Clinical Diagnostics -- 10. Imaging in vivo -- 11. Theranostics: Combining Targeting, Imaging and Therapy -- 12. Opening new horizons.
    Abstract: Fluorescence is the most popular technique in chemical and biological sensing because of its ultimate sensitivity, high temporal and spatial resolution and versatility that enables imaging within the living cells. It develops rapidly in the directions of constructing new molecular recognition units, new fluorescence reporters and in improving sensitivity of response up to detection of single molecules. Its application areas range from control of industrial processes to environment monitoring and clinical diagnostics. This book provides systematic knowledge of basic principles in design of fluorescence sensing and imaging techniques together with critical analysis of recent developments. Being a guide for students and young researchers, it also addresses professionals involved in active basic and applied research. Making a strong link between education, research and product development, this book discusses prospects for future progress.
    Type of Medium: Online Resource
    Pages: XXI, 761 p. 290 illus., 260 illus. in color. , online resource.
    Edition: 3rd ed. 2023.
    ISBN: 9783031190896
    DDC: 610.72
    Language: English
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  • 20
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Clinical medicine Research. ; Medical sciences. ; Drug development. ; Bioethics. ; Medical Ethics. ; Biomedical Research. ; Clinical Research. ; Preclinical Research. ; Bioethics. ; Medical Ethics.
    Description / Table of Contents: Chap 1. Research Environment -- Chap 2. Training, Supervision and Mentoring -- Chap 3. Research Procedures -- Chap 4. Safeguards -- Chap 5. Data Practices and Management -- Chap 6. Collaborative Working -- Chap 7. Publication and Dissemination -- Chap 8. Reviewing, Evaluating and Editing -- Chap 9. How to deal with allegations of misconduct.
    Abstract: This Open Access book is a guide to good, responsible research at each step of the process of research discovery, so that a researcher at the beginning of a scientific career has a clear pathway to doing good research and producing reliable results. The textbook will give context to the practices described in the European Code of Conduct for Research Integrity, guided by the fundamental principles or research integrity – reliability, honesty, respect, and accountability. The chapters in the book follow the good practices outlined in the Code, give practical advice and address basic principles. In this way, the book is applicable to different research fields. It directs readers to various sources for further and updated information, particularly drawing from the resources available at The Embassy of Good Science, the European platform for research integrity and ethics.
    Type of Medium: Online Resource
    Pages: XIII, 135 p. 13 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031224126
    Series Statement: Collaborative Bioethics, 1
    DDC: 610.72
    Language: English
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  • 21
    Keywords: Medicine Research. ; Biology Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Introduction and History of Meningiomas -- Chapter 2. Clinical Presentation and Prognosis -- Chapter 3. Imaging Characteristics of Meningiomas -- Chapter 4. Histopathology of Meningiomas -- Chapter 5. Skull Base Meningiomas -- Chapter 6. Spinal Meningiomas -- Chapter 7. Surgical Therapies -- Chapter 8. Radiation Therapies -- Chapter 9. Illustrative Cases -- Chapter 10. Advances in CNS Tumor Classification -- Chapter 11. Genomic Landscape -- Chapter 12. Radiation-Induced Meningiomas -- Chapter 13. Meningioma Predisposing Syndromes -- Chapter 14. Epigentic Landscape -- Chapter 15. Immune Profile -- Chapter 16. PDX Models/Mouse Models/Cell Lines -- Chapter 17. Novel Medical Therapies -- Chapter 18. Quality of Life in Menigioma Patients -- Chapter 19. Illustrative Cases: Revisited with Adjuvant Molecular Data -- Chapter 20. Future Directions in Management.
    Abstract: "Meningiomas are tumors that originate from the arachnoidal cap cells of the leptomeninges. With an incidence rate of 8.36 per 100, 000 population, they are the most common primary central nervous system (CNS) tumors, accounting for a third of all cases. The World Health Organization (WHO) classification has traditionally categorized meningiomas into 15 different histopathological subtypes and three clinical grades. Tumors are classified as WHO grades 1, 2 or 3 based largely on histopathological features such as mitotic activity, presence of brain invasion, and other atypical features. However, there is increasing recognition of the limitations of histopathology including but not limited to: confounding factors such as sampling bias in a heterogeneous tumor, and technical factors related to the experience of the grading pathologist. Even with careful histologic grading, there remains significant variability in recurrence rates within each tumor grade. As more studies have uncovered the molecular features of meningiomas, novel biological alterations have helped refine classification schemes that more accurately reflect patient outcomes. This book reviews the current state of knowledge on the genomic and epigenomic landscape of meningiomas in order to identify the roles of genomic aberrations on diagnosis, prognosis, and treatment of meningiomas in addition to mainstays of surgical management, radiation therapy, and potential novel chemotherapies. Written by a team of world-renowned experts in neurosurgery, neuropathology, radiology, and radiation-oncology, this book is the definitive resource on meningioma management and investigation for both clinicians and scientists alike.".
    Type of Medium: Online Resource
    Pages: XVII, 255 p. 55 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031297502
    Series Statement: Advances in Experimental Medicine and Biology, 1416
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Biophysics. ; Medical physics. ; Signal processing. ; Bioinformatics. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Biophysics. ; Medical Physics. ; Signal, Speech and Image Processing . ; Bioinformatics.
    Description / Table of Contents: Preface -- Part I: Backscatter Coefficient methods -- Chapter 1. Quantitative Ultrasound: an Emerging Technology for Detecting, Diagnosing, Imaging, Evaluating, and Monitoring Disease (Ernie Feleppa) -- Chapter 2. Quantitative Ultrasound: Scattering theory (Michael Oelze) -- Chapter 3. Quantitative Ultrasound: Experimental implementation (Michael Oelze) -- Chapter 4. Extracting Quantitative Ultrasonic Parameters from the Backscatter Coefficient (Aiguo Han) -- Part II: Attenuation Estimation Methods -- Chapter 5. Attenuation Compensation and Estimation (Timothy Bigelow and Yassin Labyed) -- Chapter 6. Recent advances in attenuation estimation (Ivan Rosado Mendez) -- Part III: Envelope Statistics Methods -- Chapter 7. Review of envelope statistics models for quantitative ultrasound imaging and tissue characterization (Francois Destrempes and Guy Cloutier) -- Chapter 8. Information entropy and its applications (Po-Hsaing Tsui) -- Part IV: Ultrasound Computed Tomography -- Chapter 9. Ultrasound Tomography (Nicole Ruiter, Torsten Hopp, Michael Zapf and Hartmut Gemmek) -- Chapter 10. Full Wave Inversion and Inverse Scattering in Ultrasound Tomography/Volography (James Wiskin) -- Chapter 11. Clinical Importance of 3D Volography in Breast Imaging (John Klock) -- Part V: Acoustic microcopy -- Chapter 12. Acoustic Microscopy (Yoshifumi Saijo) -- Chapter 13. Advanced Topics in Quantitative Acoustic Microscopy (Cameron Hoerig and Jonathan Mamou) -- Part VI: Phantoms for Quantitative Ultrasound -- Chapter 14. Phantoms for Quantitative Ultrasound (Tim Stiles) -- Index.
    Abstract: Quantitative ultrasound (QUS) continues to mature as a research field and is primed to make a swift transition to routine preclinical and clinical applications. This book will serve two main purposes: Advanced education in QUS by providing a complete and thorough review of all theoretical, physical, and engineering aspects of QUS. Review of recent development of QUS by lead contributors in the research field. This 2nd edition will focus on 6 modern research topics related to quantitative ultrasound of soft tissues: Spectral-based methods for tissue characterization, tissue typing, cancer detection, etc. Attenuation estimation for tissue characterization and improving spectral based methods Envelope statistics analysis as a means of quantifying and imaging tissue properties. Ultrasound computed tomography for preclinical and clinical imaging. Scanning acoustic microscopy for forming images of mechanical properties of soft tissues with micron resolution. Phantoms for quantitative ultrasound.
    Type of Medium: Online Resource
    Pages: X, 307 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031219870
    Series Statement: Advances in Experimental Medicine and Biology, 1403
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Cartography. ; Software engineering. ; Application software. ; Geographical Information System. ; Cartography. ; Software Engineering. ; Computer and Information Systems Applications.
    Description / Table of Contents: Chapter 1: Introduction to Participatory Mapping Software and Evaluation -- Chapter 2: Collector for ArcGIS -- Chapter 3: Field Papers -- Chapter 4: GeoODK -- Chapter 5: Maptionnaire -- Chapter 6: KoBoToolbox -- Chapter 7: SeaSketch -- Chapter 8: Sapelli -- Chapter 9: Survey123 -- Chapter 10: Ushahidi -- Chapter 11: Mapeo -- Chapter 12: Terrastories -- Chapter 13: Portable OpenStreetMap -- Chapter 14: MapBox -- Chapter 15: Trends and Conclusions.
    Abstract: This volume provides a framework for evaluating geospatial software for participatory mapping. The evaluation is based on ten key indicators: ethics, cost, technical level, inclusiveness, data accuracy, data privacy, analytical capacity, visualization capacity, openness, and accessibility (i.e., mobile friendly or offline capabilities). Each application is evaluated by a user and cross analyzed with specific case studies of the software’s real-world application. This framework does not discriminate against assessing volunteered geographic information (VGI) applications, as a form of participatory mapping, in circumstances that its application is spearheaded by underrepresented groups with the intent to empower and spark political or behavioral change within formal and informal institutions. Each chapter follows a strict template to ensure that the information within the volume can be updated periodically to match the ever-changing technological environment. The book covers twelve different mapping applications with the goal of creating a comparative evaluation framework that can be easily interpreted by convening institutions and novice users. This will also help identify gaps in software for participatory mapping which will help to inform application development in the future and updates to current geospatial software.
    Type of Medium: Online Resource
    Pages: XXV, 265 p. 69 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031195945
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Environmental geography. ; Sustainability. ; Geographical Information System. ; Integrated Geography. ; Sustainability.
    Description / Table of Contents: Chapter1. Flood Susceptibility Mapping Using a Frequency Ratio Model: A Case Study of Chai Nat Province, Thailand -- Chapter2. Influence of Hydrosphere Material Knowledge on the Attitude of High School Students in Conducting Water Conservation in Brebes Regency, Indonesia -- Chapter3. Optimizing multi-reservoir systems with the aid of genetic algorithm: Mahanadi reservoir project complex,Chhattisgarh -- Chapter4. Monitoring of Morphological Change in Lam Phachi River Using Geo-Informatics System -- Chapter5. Developing Scenario of Plastic Waste Leakage in Jakarta Hydrology Environment using Seasonal Data Condition and Socio-Economic Aspects -- Chapter6. Measurement of PM10, PM2.5, NO2, and SO2 Using Sensors -- Chapter7. Encoding Social Media Wording Indexes to Analyse PM2.5 Problem Perception -- Chapter8. Noise mapping of different zones in an urban area during Deepawali festival -- Chapter9. Digital Twins in farming with the implementation of agricultural technologies -- Chapter10. A cross-comparison between Rice Crop Monitoring System: GISTDA and International Asian Harvest mOnitoring system for Rice (INAHOR): JAXA -- Chapter11. Evaluation MODIS and Sentinel-2 data for detecting crop residue burned area -- Chapter12. Machine Learning Approach with Environmental Pollution and Geospatial Information for Mapping Poverty in Thailand -- Chapter13. Integration of Machine Learning Algorithms and Time-series Satellite images on Land Use/Land Cover Mapping with Google Earth Engine -- Chapter14. Sugarcane and Cassava Classification using Machine Learning Approach based on Multi-temporal Remote Sensing Data Analysis -- Chapter15. Google Earth Engine algorithm for Evaluating the Performance of Landsat OLI-8 and Sentinel-2 in Mangrove Monitoring -- Chapter16. Estimation of Aboveground Biomass and Carbon Stock using Remote Sensing Data for Sakaerat Environmental Research Station, Thailand -- Chapter17. Determination of Land Suitability for Oil Palm with Multi-Dimension Decision Support using Analytic Network Process (ANP) in Southern Thailand -- Chapter18. Land use change and ecosystem service variations in Huai Luang River basin, Udon Thani province, Thailand -- Chapter19. The Ability to Access Attractions for the Elderly from Public Transport in Bangkok Metropolis.
    Abstract: This volume presents the proceedings of the 2nd International Conference of Geography and Geoinformatics for Sustainable Development (ICGGS), held in Phuket, Thailand, April 7-8, 2022. The collection focuses on the importance of spatial thinking and planning by applying geography concepts and geospatial technology innovations in solving global problems such as environmental degradation, urban pollution, and climate change. The proceedings consist of case studies on wide-ranging spatial issues in developing countries, addressing challenges in mainstreaming sustainable development paradigms into their economies to improve natural resource and environmental management. One of the main goals of the volume is to share and exchange different points of view regarding global, regional, and local spatial issues and how to use geography and geoinformatics for building resilience in multiple sectors, e.g., water, ecosystems, agriculture, and health. It offers the opportunity to learn about how geospatial concepts and technologies can contribute to environmental sustainability, while advancing education and research related to geography and geoinformatics. It will be a useful resource for students and researchers to initiate research ideas related to geospatial topics in regional and local scales.
    Type of Medium: Online Resource
    Pages: VI, 260 p. 119 illus., 111 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031162176
    Series Statement: Springer Geography,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Mathematics Data processing. ; Mathematical statistics Data processing. ; Geographical Information System. ; Computational Mathematics and Numerical Analysis. ; Statistics and Computing.
    Description / Table of Contents: Introduction -- Locally Refined Splines -- Adaptive surface Fitting with Local Refinement: LR B-spline Surfaces -- A Statistical Criterion to Judge the Goodness of Fit of LR B-splines Surface Approximation -- LR B-splines for Representation of Terrain and Seabed: Data Fusion, Outliers, and Voids -- LR B-spline Surfaces and Volumes for Deformation Analysis of Terrain Data -- Conclusion.
    Abstract: This open access book provides insights into the novel Locally Refined B-spline (LR B-spline) surface format, which is suited for representing terrain and seabed data in a compact way. It provides an alternative to the well know raster and triangulated surface representations. An LR B-spline surface has an overall smooth behavior and allows the modeling of local details with only a limited growth in data volume. In regions where many data points belong to the same smooth area, LR B-splines allow a very lean representation of the shape by locally adapting the resolution of the spline space to the size and local shape variations of the region. The iterative method can be modified to improve the accuracy in particular domains of a point cloud. The use of statistical information criterion can help determining the optimal threshold, the number of iterations to perform as well as some parameters of the underlying mathematical functions (degree of the splines, parameter representation). The resulting surfaces are well suited for analysis and computing secondary information such as contour curves and minimum and maximum points. Also deformation analysis are potential applications of fitting point clouds with LR B-splines.
    Type of Medium: Online Resource
    Pages: XIX, 111 p. 61 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031169540
    Series Statement: SpringerBriefs in Earth System Sciences,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Big data. ; Database management. ; Algorithms. ; Data mining. ; Geographical Information System. ; Big Data. ; Database Management. ; Algorithms. ; Data Mining and Knowledge Discovery.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Remote Sensing -- Chapter 3: Special Features of Remote Sensing Big Data -- Chapter 4: Remote Sensing Big Data Collection Challenges and Cyberinfrastructure and Sensor Web Solutions -- Chapter 5: Remote Sensing Big Data Computing -- Chapter 6: Remote Sensing Big Data Management -- Chapter 7: Standards for Big Data Management -- Chapter 8: Implementation Examples of Big Data Management Systems for Remote Sensing -- Chapter 9: Big Data Analytics for Remote Sensing-Concepts and standards -- Chapter 10: Big Data Analytic Platforms -- Chapter 11: Algorithmic Design Considerations of Big Data Analytics -- Chapter 12: Machine learning and data mining algorithms for geospatial big data -- Chapter 13: Modeling, prediction, and decision making based on remote sensing big data -- Chapter 14: Examples of remote sensing applications of big data analytics-fusion of diverse earth observation data -- Chapter 15: Examples of remote sensing applications of big data analytics-agricultural drought monitoring and forecasting -- Chapter 16: Examples of remote sensing applications of big data analytics-land cover time series creation -- Chapter 17: Geospatial big data initiatives in the world -- Chapter 18: Challenges and opportunities in remote sensing big data.
    Abstract: This monograph provides comprehensive coverage of the collection, management, and use of big data obtained from remote sensing. The book begins with an introduction to the basics of big data and remote sensing, laying the groundwork for the more specialized information to follow. The volume then goes on to address a wide variety of topics related to the use and management of remote sensing big data, including hot topics such as analysis through machine learning, cyberinfrastructure, and modeling. Examples on how to use the results of big data analysis of remotely sensed data for concrete decision-making are offered as well. The closing chapters discuss geospatial big data initiatives throughout the world and future challenges and opportunities for remote sensing big data applications. The audience for this book includes researchers at the intersection of geoscience and data science, senior undergraduate and graduate students, and anyone else interested in how large datasets obtained through remote sensing can be best utilized. The book presents a culmination of 30 years of research from renowned spatial scientists Drs. Liping Di and Eugene Yu.
    Type of Medium: Online Resource
    Pages: XI, 295 p. 104 illus., 95 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031339325
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Environment. ; Geography. ; Geographical Information System. ; Environmental Sciences. ; Geography.
    Description / Table of Contents: Chapter 1: Introduction to ArcGISPro -- Chapter 2: Data Classification and Layout in ArcGISPro -- Chapter 3: Data Acquisition -- Chapter 4: Coordinate Systems and Projections -- Chapter 5: Working with Geodatabase -- Chapter 6: Data Editing and Topology -- Chapter 7: Geoprocessing -- Chapter 8: Site Suitability and Data Modelling -- Chapter 9: Geocoding -- Chapter 10: Working with Raster -- Chapter 11: Spatial Interpolation -- Chapter 12: Watershed Delineation -- Chapter 13: Special Statistics -- Chapter 14: Network Analyst -- Chapter 15: 3-D Analyst -- Chapter 16: ArcGIS Online and Web Maps.
    Abstract: This textbook serves as a practical guide for undergraduate and graduate students in geology, hydrology, ecology, and environmental sciences, teaching them applied GIS techniques. Presented as a step-by-step tutorial across seventeen chapters, the book starts with the fundamentals of GIS and progresses to real-life examples from geology and water resources. The focus is on ESRI's ArcGIS Pro, covering various tools for spatial, geostatistical, network, and 3-D analysis. Additionally, it explores ArcGIS Online and working with web apps like Web Map, StoryMaps, and GEO App. GIS applications, especially in water and environmental problem-solving, are rapidly growing worldwide. The demand for GIS experts utilizing spatial analysis in environmental science remains high. This textbook equips users with the necessary knowledge to become effective mappers and spatial analysts in the fields of environment, geosciences, and water resources, employing the latest state-of-the-art methodology. Each chapter provides exercises and supplementary materials available for download on SpringerLink, along with additional links for further learning opportunities.
    Type of Medium: Online Resource
    Pages: XIX, 424 p. 669 illus., 653 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031422270
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical policy. ; Quality of life. ; Biomedical Research. ; Health Policy. ; Quality of Life Research.
    Description / Table of Contents: Foreword: Challenges & Opportunities for LGBT Populations and Cancer in Global Oncology -- Introduction -- Africa -- A Double Dose Of Stigma – Being Gay And Living With Cancer In Kenya -- Sexual Orientation, Gender Identity and Cancer in South Africa -- Americas -- Making the Situation of TLGBI People around Cancer visible: Observations from the Andean Region -- Cancer Care Challenges for the LGBT Population in Brazil -- Cancer and the SGM Population in Canada and the United States of America -- South-East Asia -- The South-East Asia Region: Societal Conditions for LGBT Health and Cancer Research -- Europe -- Foreword: The Eurocentralasian Lesbian* Community Perspective on Cancer and LBQ women: Advocating for more Research and Activism Collaboration -- LGBT+ and Cancer in the WHO European Region: Current Situation in 12 Eastern European and Central Asian Countries -- Sexual and Gender Minorities and Cancer in Germany: The Striking Absence of Understanding their Cancer-related Needs -- LGBT Populations and Cancer in the UK -- Eastern Mediterranean -- LGBT Populations and Cancer in the Eastern Mediterranean Region: Insights and Challenges with a Focus on Lebanon -- Western Pacific -- LGBT Populations and Cancer in Australia and New Zealand -- Challenges in Cancer Control Confronting the LGBT Population in China: Health Risks, Unique Barriers, and Unmet Needs -- What Have We Learned about Cancer and the Global LGBT Community? -- Index.
    Abstract: Lesbian, Gay, Bisexual, and Transgender (LGBT) also known as sexual and gender minority (SGM) populations have been the focus of global attention. Most importantly, LGBT populations have been addressed in the context of human rights in multiple reports and other activities by the United Nations and other international organizations. There is great variation among countries in the recognition of LGBT individuals’ human rights. A global focus on LGBT populations’ health is still limited, with the notable exception of HIV research. This book on LGBT populations and cancer in the global context is, therefore, an important step in that it will broaden the focus on LGBT populations’ health. Globally, cancer is the second leading cause of death. Cancer morbidity and mortality are increasing disproportionately among populations in lower-income countries. A review conducted by the World Health Organization (WHO) found that of the 82% of member states (158) countries, only 35% of the national cancer control plans addresses vulnerable population, including LGBT populations. These findings reflect an increasing awareness about equity when addressing cancer prevention and control, including LGBT populations. This book addresses LGBT populations’ cancer burden across countries that range from high- to low-income countries to support efforts in diverse countries that are working towards reducing LGBT populations’ cancer burden. It documents place-specific challenges that impede progress towards reducing the LGBT cancer burden as well as critically assesses the variation in cancer control efforts that target LGBT populations and cancer to support progress at a global scale. This book includes six sections that cover the six WHO regions, with each chapter written by an author from the specific region s/he is covering. Each chapter makes use of a template that contextualizes the region, local data collection/availability, risk factors, cancer prevention, detection, diagnosis, treatment, and survivorship.
    Type of Medium: Online Resource
    Pages: X, 335 p. 3 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065859
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Parasitology. ; Biomedical Research. ; Medical Microbiology. ; Parasitology.
    Description / Table of Contents: Preface -- Chapter1. Advances in experimental research about periodontitis: lessons from the past, ideas for the future (Julien Santi-Rocca) -- Part I: Periodontal microbiota -- Chapter 2. Microbiota in Periodontitis: advances in the omic era (Shao Bing Fong, Emile Boyer, Martine Bonnaure-Mallet, Vincent Meuric) -- Chapter 3. Aggregatibacter actinomycetemcomitans: from basic to advanced research (Abdelhadi Hbibi, Amal Bouziane, Badiaa Lyoussi, Mimoun Zouhdi, Driss Benazza) -- Chapter 4. Meta-analyses on the Periodontal Archaeome (Jéssica Alves de Cena, Yuri Silvestre-Barbosa, Aline Belmok, Cristine Miron Stefani, Cynthia Maria Kyaw, Nailê Damé-Teixeira) -- Chapter 5. Parasites in periodontal health and disease: a systematic review and meta-analysis (David Felipe Martin-Garcia, Malik Sallam, Gabriela Garcia, Julien Santi-Rocca) -- Chapter 6. Fungi - a component of the oral microbiome involved in periodontal diseases (Justyna Karkowska-Kuleta, Dorota Satala, Magdalena Smolarz, Marcin Zawrotniak, Maria Rapala-Kozik) -- Chapter 7. Herpesviruses in periodontitis: An umbrella review (Aleksandar Jakovljevic, Miroslav Andric, Jelena Jacimovic, Jelena Milasin, Javier Enrique Botero) -- Part II: Periodontitis pathophysiology -- Chapter 8. Recent updates on microbial biofilms in periodontitis: an analysis of in vitro biofilm models (Maick Meneguzzo Prado, Nathalia Figueiredo, Andréa Pimenta, Tamires Szeremeske Miranda, Magda Feres, Luciene Cristina Figueiredo, Josiane de Almeida, Bruno Bueno-Silva) -- Chapter 9. Update on B cell response in periodontitis (Julien Demoersman, Jacques Olivier Pers) -- Chapter 10. Polarization profiles of T lymphocytes and macrophages responses in periodontitis (Franco Cavalla, Marcela Hernández) -- Chapter 11. Complementary experimental methods in genetics open up new avenues of research to elucidate the pathogenesis of periodontitis (Arne S. Schaefer) -- Part III: Periodontitis-associated conditions -- Chapter 12. Update on the bidirectional link between diabetes and periodontitis (Leila Salhi, Michèle Reners) -- Chapter 13. Periodontitis as a risk factor for Alzheimer’s disease: the experimental journey so far, with hope of therapy (Alice Harding, Shalini Kanagasingam, Richard Welbury, Sim K. Singhrao) -- Chapter 14. Cardiovascular diseases and periodontitis (Peter Riis Hansen, Palle Holmstrup) -- Part IV: Therapeutic management of periodontitis -- Chapter 15. Update on the role of cytokines as oral biomarkers in the diagnosis of periodontitis (Triana Blanco-Pintos, Alba Regueira-Iglesias, Carlos Balsa-Castro, Inmaculada Tomás) -- Chapter 16. Non-surgical periodontal treatment: SRP and innovative therapeutic approaches (Alexia Vinel, Antoine Al Halabi, Sébastien Roumi, Hélène Le Neindre, Pierre Millavet, Marion Simon, Constance Cuny, Jean-Sébastien Barthet, Pierre Barthet, Sara Laurencin-Dalicieux) -- Chapter 17. Update on the roles of oral hygiene and plaque control on periodontal disease (Leila Salhi, Bruno De Carvalho, Michèle Reners) -- Chapter 18. Multi-photonic adjunctive therapy for the management of periodontitis: recent advances and new treatment approach (Marco Giannelli, Daniele Bani) -- Chapter 19. Probiotics during the therapeutic management of periodontitis (Flavia Furlaneto, Karin Hitomi Ishikawa, Michel Reis Messora, Marcia P A Mayer) -- Chapter 20. Periodontal cell therapy: a systematic review and meta-analysis (Antoine Dubuc, Valérie Planat-Bénard, Mathieu Marty, Paul Monsarrat, Philippe Kémoun) -- Index.
    Abstract: Periodontitis is a disease that affects more than half the adult population in the world. Treatment is often based on ancient recommendations consisting in mechanically removing material from damaged zones. However, novel therapeutic management strategies exist, from prevention to efficient treatment, and regeneration. The need of integrative approaches to circumvent this worldwide pledge can be achieved through: A better understanding of this complex disease by promoting scientific research and a comprehensive multidisciplinary approach, including epidemiology, microbiology, immunology, physiology, therapeutics, psychology, etc. A better outreach by promoting vulgarization and recommendations for health professionals. A better information of the empowered patients, leading them to consider prevention and to take part in their therapeutic course. The book “Periodontitis: Advances in Experimental Research” includes a timely collection of chapters covering all the fields of research about periodontitis, consisting in concise reviews by the best specialists themselves and with clinical perspectives for periodontitis. Recent technological advances have allowed to explore shadowed areas of periodontology. The book “Periodontitis: Advances in Experimental Research” is a unique occasion to set a milestone for a more integrated field of periodontitis, with a broad scientific, medical, and public audience thanks to dedicated sections in each chapter: Abstract and main body (scientific audience and expert clinicians) Highlights (scientific audience and clinicians) Impact for Practice (clinicians and economical/political decision makers) Summary for Patients (patients and economical/political decision makers).
    Type of Medium: Online Resource
    Pages: XIII, 402 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968816
    Series Statement: Advances in Experimental Medicine and Biology, 1373
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Life sciences. ; Chemistry, Organic. ; Enzymology. ; Biochemistry. ; Biomedical Research. ; Life Sciences. ; Organic Chemistry. ; Enzymology. ; Biochemistry.
    Description / Table of Contents: 1. Alkanes, composition, constitution, and configuration -- 2. Functional groups -- 3. Electronic structure of organic molecules -- 4. Alkenes and alkynes -- 5. Substitutions on saturated carbon atom -- 6. Nucleophilic additions -- 7. Stereochemistry, symmetry, and molecular chirality -- 8. Derivatives of carboxylic acids -- 9. Electrophilic substitutions -- 10. Pericyclic reactions -- 11. Organic natural products -- 12. Organic supramolecular and supermolecular structures.
    Abstract: This textbook is designed for students of biology, molecular biology, ecology,medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions.
    Type of Medium: Online Resource
    Pages: XV, 205 p. 339 illus., 114 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030924386
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Internal medicine. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Internal Medicine. ; Physiology.
    Description / Table of Contents: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges -- Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer -- Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk -- Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics -- Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research -- Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions -- Ion Transport and Radioresistance -- Ion Transporting Proteins and Cancer: Progress and Perspectives.
    Abstract: Targeting Ion Channels for Cancer Treatment: Current Progress and Future Challenges Alina L. Capatina, Dimitris Lagos, and William J. Brackenbury Novel Therapeutic Approaches of Ion Channels and Transporters in Cancer Ana Ramírez, Janice García-Quiroz, Luis Aguilar-Eslava, Yesennia Sánchez-Pérez, and Javier Camacho Ion Channels in Cancer: Orchestrators of Electrical Signaling and Cellular Crosstalk Jerry J. Fan and Xi Huang Potassium and Chloride Ion Channels in Cancer: A Novel Paradigm for Cancer Therapeutics Umberto Banderali, Luigi Leanza, Najmeh Eskandari, and Saverio Gentile Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research Marie Potier-Cartereau, William Raoul, Gunther Weber, Karine Mahéo, Raphael Rapetti-Mauss, Maxime Gueguinou, Paul Buscaglia, Caroline Goupille, Nelig Le Goux, Souleymane Abdoul-Azize, Thierry Lecomte, Gaëlle Fromont, Aurélie Chantome, Olivier Mignen, Olivier Soriani, and Christophe Vandier Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions Jason T. Anderson, Kevin M. Huang, Maryam B. Lustberg, Alex Sparreboom, and Shuiying Hu Ion Transport and Radioresistance Bastian Roth and Stephan M. Huber Ion Transporting Proteins and Cancer: Progress and Perspectives Mustafa B. A. Djamgoz.
    Type of Medium: Online Resource
    Pages: X, 277 p. 30 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031039942
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 183
    DDC: 610.72
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Molecular biology. ; Metabolism. ; Genetics. ; Cytology. ; Biomedical Research. ; Molecular Biology. ; Metabolism. ; Genetics and Genomics. ; Cell Biology.
    Description / Table of Contents: Introduction (Moray J Campbell & Charlotte L Bevan) -- Overview (Jason Carroll) -- Part I: Reproduction and Development -- Chapter 1. Nuclear receptors in pregnancy and outcomes: clinical perspective (Luiza Borges Manna & Catherine Williamson) -- Chapter 2. Female Reproductive Systems: hormone dependence and receptor expression (Philippa TK Saunders) -- Chapter 3. Nuclear receptors in ovarian function (Darryl Russell & Doan Thao Dinh) -- Part II: Metabolism -- Chapter 4. Nuclear receptors in energy metabolism (Alina Walth, Stephan Herzig & Maria Rohm) -- Chapter 5. Nuclear Receptors and lipid sensing (James L Thorne and Giorgia Cioccoloni) -- Part III: Central Systems -- Chapter 6. Corticosteroid receptors in Cardiac health and disease (Jessica Ivy, Gillian Gray, Megan Holmes, Martin Denvir, Karen Chapman) -- Chapter 7. Physiological convergence and antagonism between GR and PPARγ in inflammation and metabolism (Marija Dacic, Gayathri Shibu and Inez Rogatsky) -- Chapter 8. Circadian Rhythm and Nuclear Receptors (David W Ray) -- Chapter 9. Vitamin D and gut health (James C Fleet) -- Part IV: Cancer -- Chapter 10. Estrogen Receptor alpha and ESR1 Mutations in Breast Cancer (Jaymin Patel & Rinath Jeselsohn) -- Chapter 11. AR structural variants and prostate cancer (Laura Cato) -- Chapter 12. ERβ and inflammation (Linnea Hases, Amena Archer & Cecilia Williams) -- Chapter 13. Genomic insights into non-steroidal nuclear receptors in prostate and breast cancer (Sajad A Wani & Moray Campbell) -- Part V: New developments in transcriptional control by nuclear receptors -- Chapter 14. Protein condensation in the nuclear receptor family; implications for transcriptional output (Monique Appelman, Elle Hollaar, Jurian Schuijers & Saskia WC van Mil) -- Chapter 15. Prostate cancer epigenetic plasticity and enhancer heterogeneity: molecular causes, consequences and clinical implications (Jeroen Kneppers, Andries M Bergman & Wilbert Zwart) -- Chapter 16. Epigenetic coregulation of androgen receptor signaling (Rayzel Fernandes, Damien A. Leach & Charlotte Bevan) -- Part VI: Clinical Translation -- Chapter 17. Cllnical Translation: Targeting the Estrogen Receptor (Jennifer O. Lauchle & Ciara Metcalfe) -- Chapter 18. Drugging the undruggable: targeting the N-terminal domain of nuclear hormone receptors (Marianne Sadar) -- Chapter 19. Genetic Variation and Mendelian Randomization approaches (Mojgan Yazdanpanah, Nahid Yazdanpanah & Despoina Manousaki) -- Index.
    Abstract: This book addresses and dissects the roles and crosstalk mechanisms for the 48 human nuclear receptors (NR) in human health and disease. After a State-of-the-Art introduction by an undisputed and celebrated field leader to provide an overview of the field and its significance, chapters are organized into six sections. The first three sections discuss NR roles in Reproduction & Development, Metabolism and Central Systems. These present to the reader our current understanding of NR signaling in the development and functioning of the reproductive system; the roles in the regulation of energy metabolism; and how NR signaling is more widely integrated into systemic functions from calcium flux to circadian rhythm. The subsequent three sections dissect how aberrant NR functions drive Cancer; how new insights into Genomic Interaction are helping to reveal how NR disruption drives disease; and finally, how Translational Efforts are exploiting this understanding from developing novel NR ligands to establishing how underlying genetic variation impacts NR function. Within these sections the chapters also illustrate emerging understanding of how the epigenome and non-coding genome combine to regulate NR function and impact dysfunction. Increasingly these insights cross-fertilize over cell and disease boundaries and it is unsurprising that NR are being explored in novel and new arenas such as the context of neurological disorders and depression. Thus, there is wide scope for re-purposing of licensed drugs and development of new NR-targeting therapies for a host of conditions and diseases. This unique book brings together many of the leading figures in NR research from across the globe, to discuss emerging roles and their implications for human health and disease. It summarizes the state of the art and shows signposts for future research to further shape this influential field.
    Type of Medium: Online Resource
    Pages: XII, 346 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031118364
    Series Statement: Advances in Experimental Medicine and Biology, 1390
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Anatomy. ; Medical education. ; Virtual reality. ; Augmented reality. ; Biomedical Research. ; Anatomy. ; Medical Education. ; Virtual and Augmented Reality.
    Description / Table of Contents: Part I. Healthcare -- Chapter 1. Is It Time to FONA Friend? A Novel Mixed Reality Front of Neck Access Simulator -- Chapter 2. “Learning About Skin Breakdown” – Design, Development and Evaluation of an Augmented Reality Application to Inform about Pressure Ulcers (sores) and Moisture Lesions -- Chapter 3. The Use of 3D-Printing and Injection Moulding in the Development of a Low-Cost, Perfused Renal Malignancy Model for Training of Robot-Assisted Laparoscopic Partial Nephrectomy -- Chapter 4. The Co-IMMUNicate App: An Engaging and Entertaining Education Resource on Immunity to Respiratory Viruses -- Part II. Education -- Chapter 5. Application of AR and 3D Technology for Learning Neuroanatomy -- Chapter 6. Communicative Powers of Interactive Digital Mediums in the Field of Polyomics -- Chapter 7. SkilletonVR: Canine Skeleton VR -- Chapter 8. Using Holograms to Engage Young People with Anatomy -- Chapter 9. The Digital Dolphin: Are 3D Mobile Based and Interactive Models a Useful Aid to Volunteers on Stranding Schemes Learning the Basic Anatomy and Pathology of Cetaceans? -- Chapter 10. The Impact of the COVID Crisis on Anatomical Education: A Systematic Review.
    Abstract: This edited book explores the use of technology to enable us to visualize the life sciences in a more meaningful and engaging way. It will enable those interested in visualization techniques to gain a better understanding of the applications that can be used in visualization, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualization techniques and technologies for the historical and forensic settings. The reader will be able to explore the utilization of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences. We have something for a diverse and inclusive audience ranging from healthcare, patient education, animal health and disease and pedagogies around the use of technologies in these related fields. The first four chapters cover healthcare and detail how technology can be used to illustrate emergency surgical access to the airway, pressure sores, robotic surgery in partial nephrectomy, and respiratory viruses. The last six chapters in the education section cover augmented reality and learning neuroanatomy, historical artefacts, virtual reality in canine anatomy, holograms to educate children in cardiothoracic anatomy, 3D models of cetaceans, and the impact of the pandemic on digital anatomical educational resources.
    Type of Medium: Online Resource
    Pages: IX, 323 p. 270 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031067358
    Series Statement: Biomedical Visualization, 1
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Nanotechnology. ; Cancer Treatment. ; Biomedical Research. ; Nanotechnology. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1. The tumor microenvironment -- Chapter 2. Methods of formulation of polymeric nanoparticles -- Chapter 3. Natural polymers based nanoparticles targeted to solid tumors -- Chapter 4. Optimization of physicochemical properties of polymeric nanoparticles for targeting solid tumors -- Chapter 5. Passive and active targeting approaches for solid tumors -- Chapter 6. Polymeric nanoparticles entrapping natural drugs for cancer therapy -- Chapter 7. Polymeric nanoparticles entrapping drug combinations targeted to solid tumors -- Chapter 8. Ligands specific to over-expressed receptors in solid tumors -- Chapter 9. Ligand targeted polymeric nanoparticles for cancer chemotherapy -- Chapter 10. Polymeric nanoparticles as theranostics for targeting solid tumors -- Chapter 11. Oral delivery of polymeric nanoparticles for solid tumors -- Chapter 12. Polymeric nanoparticles to target glioblastoma tumors -- Chapter 13. Polymeric nanoparticles to target lung cancer -- Chapter 14. Polymer based nanoplatforms for targeting breast cancer -- Chapter 15. PH-Sensitive polymeric nanoparticles for cancer treatment -- Chapter 16. Polymeric nanoplatforms for targeted treatment of prostate cancer -- Chapter 17. Cellular internalization and toxicity of polymeric nanoparticles -- Chapter 18. Prospects and challenges in the treatment of solid tumors.
    Abstract: This book focuses on the emerging research in the field of treatment of solid tumors or cancer with new drug delivery systems using nanotechnology. Nanotechnology has given us a good scope for development of new innovative drug delivery strategies to increase the therapeutic efficacy of anticancer drugs with reduced off-target side effects. Cancer is one of the main causes of death worldwide due to the limitations of classical therapies such as low solubility of active drugs, toxic side effects on healthy cells and resistance of tumor cells. These issues are partly solved by the recent development of polymeric nanoparticles, which improve drug absorption and the therapeutic index, while reducing side effects. Drug carriers must be biocompatible, biodegradable and non-immunogenic. Coupled to a ligand that has affinity for that particular cell, polymeric nanoparticles are used to target specifically malignant cells or tissues and, in turn, improve drug stability. This book presents the latest advances in the application of polymeric particles for cancer treatment, with focus on the tumor microenvironment, synthesis, active and passive targeting, patents, targeting over-expressed receptors, tumor-targeting ligands, theranostics, glioblastoma tumors, lung cancer, breast cancer, prostate cancer and pH-responsive nanoparticles.
    Type of Medium: Online Resource
    Pages: X, 512 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031148484
    Series Statement: Environmental Chemistry for a Sustainable World, 71
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Stem cells. ; Biotechnology. ; Biomedical Research. ; Stem Cell Biology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. The historical studies underpinning the concept of hair follicle neogenesis (Higgins C, Jahoda C) -- Chapter 2. Hair regeneration and rejuvenation: pipeline of medical and technical strategies (Limbu S, Kemp P) -- Chapter 3. Cells and structures involved in hair follicle regeneration: an introduction (Tsai J, Garza LA) -- Chapter 4. The dermal papilla and hair follicle regeneration: Engineering strategies to improve dermal papilla inductivity (Pantelireis N, Clavel C) -- Chapter 5. Dermal sheath and hair follicle regeneration (Yoshida Y, Tsuboi K, Kishimoto J) -- Chapter 6. Epithelial-mesenchymal interactions between hair follicles and dermal adipose tissue (Ramos R, Plikus MV) -- Chapter 7. Lymphatic vasculature and hair follicle regeneration (Cazorla A, Perez-Moreno M) -- Chapter 8. In vitro and ex vivo hair follicle models to explore therapeutic options for hair regeneration (Bertolini M, Piccini I, McElwee KJ) -- Chapter 9. Extracellular vesicles including exosomes for hair follicle regeneration (Aberdam E, le Riche A, Bordes S, Closs B, Park BS, Aberdam D) -- Chapter 10. Stem cell-based therapies for hair loss: what is the evidence from a clinical perspective? (Park BS, Choi HI) -- Chapter 11. Induced pluripotent stem cell approach for hair follicle regeneration (Pinto A, Terskikh AV) -- Chapter 12. Biofabrication technologies in hair neoformation (Abreu CM, Gasperini L, Marques AP) -- Chapter 13. Wound healing induced hair follicle regeneration (Jiang Y, Myung P) -- Chapter 14. Hair follicles in wound healing and skin remodeling (Plotczyk M, Jimenez F) .
    Abstract: This book aims to comprehensively review the current cell-based strategies under investigation to achieve the regeneration of human hair follicles. The unique capacity of the human hair follicle to self-renew explains why this complex “mini-organ” has always attracted so much interest as a model for researchers to study stem cell biology and regenerative medicine. The hair follicle is considered a main reservoir of cutaneous stem cells, containing several pools of epithelial, melanocyte, and mesenchymal stem cells involved in hair follicle self-regeneration and pigmentation. In addition, while some of the different follicular cell types contribute to hair shaft growth, others participate in very important interfollicular functions such as dermal remodeling, re-epithelialization after wounding, and cutaneous stem cell homeostasis. The idea of human hair follicle regeneration either “de novo” or by activating dormant miniaturized follicles is not new, yet still continues to arouse enormous interest in the pursuit of a definitive cure for baldness. In contrast to hair follicle regeneration in mice, the attempts made with human follicles have been disappointing in terms of efficiency. However, recent advances in stem cell biology—as well as the appearance of new technologies like 3D printing—have revived expectations in this field of research. This book is divided into four sections. The first part includes an overview of the strategies used in hair follicle regeneration and a historical summary of the most important achievements to date. Parts two and three comprise the main body of the book, with detailed descriptions of the cells and tissue structures involved in hair follicle regeneration, followed by an elaboration of the different therapeutic strategies, engineering techniques, and a clinician’s perspective of stem cell-based therapies in hair loss treatments. Finally, the fourth part reviews the important contribution of the hair follicle in healing cutaneous wounds through the regeneration and remodeling of the dermis and epidermis after injury, as well as wound induced hair follicle neogenesis that occurs when the skin is injured.
    Type of Medium: Online Resource
    Pages: XII, 307 p. 73 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030983314
    Series Statement: Stem Cell Biology and Regenerative Medicine, 72
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Internal medicine. ; Bioinformatics. ; Biomedical Research. ; Internal Medicine. ; Bioinformatics.
    Description / Table of Contents: Part One: Basic Concepts in Precision Oncology -- Chapter 1. Design and Implementation of a precision oncology workflow -- Chapter 2. An overview of cancer genome sequencing -- Chapter 3. Software infrastructures for precision medicine workflows -- Part Two: Current Computational Methods and Tools in Precision Oncology -- Chapter 4. Somatic and germline variant calling from next-generation sequencing data -- Chapter 5. Identification of copy number alterations from next-generation sequencing data -- Chapter 6. Genome-wide discovery of large-scale structural variants from next-generation sequencing data -- Chapter 7. Assessment of microsatellite instability from next-generation sequencing data -- Chapter 8. Computational approaches for the investigation of intra-tumor heterogeneity and clonal evolution from bulk sequencing data -- Chapter 9. Analysis of the transcriptome for precision oncology applications -- Chapter 10. Computational methods for drug repurposing -- Chapter 11. Pathway for analysis for precision oncology applications -- Chapter 12. Identification of fusion transcripts from RNA-seq -- Chapter 13. Computational resources for the interpretation of variations in cancer -- Chapter 14. Analysis of electronic health records for precision oncology -- Chapter 15. Network approaches for precision oncology -- Chapter 16. Experimental validation of genomic alterations -- Part Three: Advanced Concepts - The Future of Precision Oncology -- Chapter 17. Molecular profiling of liquid biopsies for precision oncology -- Chapter 18. Artificial intelligence for precision oncology -- Chapter 19. Single-cell technologies in precision oncology -- Chapter 20. Computational approaches for precision immuno-oncology -- Chapter 21. Multi-pmics profiling of the tumor microenvironment -- Chapter 22. Epigenetic and precision oncology -- Chapter 23. Next generation knowledge bases to support precision oncology. .
    Abstract: Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology.
    Type of Medium: Online Resource
    Pages: XIV, 336 p. 36 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030918361
    Series Statement: Advances in Experimental Medicine and Biology, 1361
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Immunology. ; Dermatology. ; Biomedical Research. ; Medical Genetics. ; Immunology. ; Biomedical Research. ; Dermatology.
    Description / Table of Contents: Genetics control of immune responses -- Non-melanoma skin cancer -- Melanoma -- Psoriasis -- Atopic dermatitis -- Contact dermatitis -- Lichen planus -- Pemphigus and pemphigoids -- Morphea and Lichen Sclerosus -- Granuloma annulare and Necrobiosis lipoidica -- Alopecia areata -- Vitiligo -- Acne Vulgaris and Rosacea -- Urticaria and Angioedema -- Cutaneous drug reaction -- Photodermatologic disorders -- Infantile Haemangioma and other vascular malformations.
    Abstract: This book intends to investigate the broad spectrum of genetic changes in immunological processes involved in cutaneous diseases. One of the main goals of immunogenetic studies is finding susceptibility genes for complex diseases. This can provide an insight into the pathogenesis of the condition in a way that is not easily achievable through other kinds of studies. Thus they are a rational initial step for generating hypotheses about disease pathogenesis. This may especially benefit dermatology, a field notorious for having too many diseases with unknown etiologies. Immunogenetic investigations have made targeted treatment strategies possible for diseases such as psoriasis and pemphigus. Even though these strategies have revolutionized the management of chronic dermatological conditions such as psoriasis, still there are a lot of unanswered questions. For instance, psoriasis patients respond very differently to each of the commercially available biological agents. This diversity could be partially explained by the differences in the sets of genes responsible for disease induction in each individual. Thus whole genome sequencing strategies, if feasible at individual levels, might help in tailoring these targeted treatments based on specific genetic backgrounds. Our intention in preparing this book was to explore the broad spectrum of the genetic aspects of immunological processes involved in cutaneous diseases. We have tried to cover most areas of dermatology where enough studies were available to gather a chapter. Still, there is a substantial lack of knowledge on the immunogenetics of many dermatological conditions. We hope that this book would encourage the investigators to fill these gaps of knowledge.
    Type of Medium: Online Resource
    Pages: XXI, 450 p. 64 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030926168
    Series Statement: Advances in Experimental Medicine and Biology, 1367
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Veterinary medicine. ; Agricultural genome mapping. ; Biomedical Research. ; Veterinary Science. ; Agricultural Genetics.
    Description / Table of Contents: Chapter 1: Outline Of Anatomy/Physiology Of Skeletal Tissues -- Chapter 2: Tumors Of The Musculoskeletal System -- Chapter 3: Tumor-Like Lesions Of The Musculoskeletal System -- Chapter 4: General Considerations About Bone Tumors -- Chapter 5: Appendix: Manual For Histological Preparation And Examination Of Tissues Containing Bone And Cartilage.
    Abstract: This book comparatively examines the etiopathogenetic, clinical-pathological, diagnostic and therapeutic strategies of the main bone tumors of domestic animals. The book also includes a description of the most significant aspects of macroscopic, microscopic, immunohistochemical, instrumental, diagnostic imaging and molecular biology aspects of spontaneous bone tumors in Veterinary Medicine, with also interspecies comparative aspects, including the human one. Last but not least, the book provides an overview of the new diagnostic and therapeutic frontiers related to the approach to animal bone tumors. The book serves as essential reading for professionals, researchers and students who work or want to tackle three paths in the field of comparative veterinary bone oncology.
    Type of Medium: Online Resource
    Pages: XV, 193 p. 90 illus., 84 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030902100
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Tumors Classification. ; Surgery. ; Cytokines. ; Virology. ; Biomedical Research. ; Cancer Staging. ; Surgery. ; Cytokines and Growth Factors. ; Virology.
    Description / Table of Contents: Compliance with the Surgery Safety Checklist: An Update on the Status -- Surgical Safety Checklist: Polychromatic or Achromatic Design -- Surgical Strategy and Clinical Outcome in Patients with Bronchial Carcinoids -- Frozen Section or Intraoperative Cytology: Are We Ready for a Paradigm Shift in Thoracic Surgery? -- Clinical Outcome in Patients with Nosocomial COVID-19 Infection After Thoracic Surgery -- Cytological Diagnostic Procedures in Malignant Mesothelioma -- Combination of Biochemical and Cytological Findings for Better Diagnosis in Pleural Effusions -- Cytokines in Renal Cell Carcinoma: A Step Towards Earlier Detection and Targeted Therapy -- Primary Hyperparathyroidism Secondary to Ectopic Parathyroid Adenoma: A Case Report -- Perception of Well-Being and Quality of Life in Obese Patients After Bariatric Surgery -- Do Multiple Brain Lesions Always Connote Worse Outcomes? Appraisal Evidence from a Tertiary Care Center in Koshi/Purbanchal Province of Nepal -- Radioimaging and Demographic Profiles of Patients with Spontaneous Intracerebral Hemorrhage: A Need for the Pragmatic Referral System -- Anticytokine Treatment of Rheumatoid Arthritis: An Observational Report.
    Abstract: The book is an update on contentious or unsettled issues concerning invasive diagnostic and therapeutic challenges in cancer and related disorders, focusing on the surgical approach. Topics include recommendations for the best practice in using the surgery safety checklist, surgical strategies in a variety of thoracic cancers, renal cell carcinoma, tumors of parathyroid glands, mesothelioma, and bariatric surgeries. The focus is on the diagnostic and therapeutic challenges of aggressive cancerous entities, choosing the most beneficial modes for optimal outcomes and patient survival. Chapters also address radioimaging and therapy outcomes in different intracranial lesions leading to severe neurological disabilities. The areas of medical practice addressed are still veiled in uncertainty, yet-unresolved pathogenetic background, and have a substantial component of empirical rather than evidence-based clinical approach. Pursuing and sharing new ideas and innovations is essential for improving the management and outcome. The book endeavors to disseminate and deliberate on the latest medical knowledge, studies, and advancements in surgical and diagnostic dealing with cancer. The book is addressed to physicians and surgeons, and all allied health care professionals engaged in patient care and therapy.
    Type of Medium: Online Resource
    Pages: VI, 119 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030988579
    Series Statement: Clinical and Experimental Biomedicine, 1374
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Physiology.
    Description / Table of Contents: How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression -- Ion Channels, Transporters, and Sensors Interact with the Acidic Tumor Microenvironment to Modify Cancer Progression -- Role of pH Regulatory Proteins and Dysregulation of pH in Prostate Cancer -- Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues -- Circulating Tumor Cells: Does Ion Transport Contribute to Intravascular Survival, Adhesion, Extravasation, and Metastatic Organotropism?.
    Abstract: How Reciprocal Interactions Between the Tumor Microenvironment and Ion Transport Proteins Drive Cancer Progression Line O. Elingaard-Larsen, Michala G. Rolver, Ester E. Sørensen, and Stine F. Pedersen Ion Channels, Transporters, and Sensors Interact with the Acidic Tumor Microenvironment to Modify Cancer Progression Ebbe Boedtkjer Role of pH Regulatory Proteins and Dysregulation of pH in Prostate Cancer Larry Fliegel Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues Giorgia Scarpellino, Luca Munaron, Anna Rita Cantelmo, and Alessandra Fiorio Pla Circulating Tumor Cells: Does Ion Transport Contribute to Intravascular Survival, Adhesion, Extravasation, and Metastatic Organotropism? Christian Stock.
    Type of Medium: Online Resource
    Pages: XV, 175 p. 40 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030998004
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 182
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical sciences. ; Vocational guidance. ; Career education. ; Biomedical Research. ; Health Sciences. ; Career Counseling. ; Career Skills.
    Description / Table of Contents: Part 1: Getting started -- Chapter 1: The why and the what of scientific research and publishing -- Chapter 2: Understanding research ethics -- Chapter 3: How to structure a scientific article, conference poster and presentation -- Part 2: The Hidden Bumps -- Chapter 4: Who gets authorship status? -- Chapter 5: The art of journal selection -- Chapter 6: Understanding the editor’s perspectives -- Part 3: The Destination -- Chapter 7: Converting a scientific article for the media -- Chapter 8: What are research metrics and why should I care? -- Chapter 9: Beyond your scientific publication -- Chapter 10: The Editor’s Perspective – Full-Length Interviews.
    Abstract: In the age of "publish or perish," this book provides everything one needs to know about conducting research and successfully publishing it in a scientific journal. The reader learns about the complete process of scientific publishing: from selecting the most appropriate research design, to obtaining permissions and funding, to resourcefully presenting the research results in a poster and oral presentation. Additionally, the practical tips provided here help the reader formulate a compelling scientific article and choose the most suitable journal (subscription vs. the various open access modalities) for their publication. This book also addresses "invisible aspects" of scholarly publishing that are nonetheless important and that everyone should know and understand: avoiding predatory journals, understanding the editor's perspective, and becoming familiar with the various research metrics (from author to journal) that can all determine success or failure of a publication. Written in an informal style in which the author shares personal perspectives and experiences, the book is easily accessible to the reader. The book offers early career scientists in biomedicine and medicine a unique perspective on publishing research articles and how this process can enhance the authors' "scientific value" within the scientific ecosystem as well as their personal CVs.
    Type of Medium: Online Resource
    Pages: XIV, 119 p. 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030992958
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Pain medicine. ; Artificial intelligence. ; Biomedical Research. ; Pain Medicine. ; Artificial Intelligence.
    Description / Table of Contents: Artificial Intelligence and Precision Medicine: A Perspective -- Pedobarography in Physiotherapy: A Narrative Review on Current Knowledge -- Quantum Medicine: A Role of Extremely Low-Frequency Magnetic Fields in the Management of Chronic Pain -- Manual Therapy Approach to the Extraocular Muscles in Migraine Treatment: A Preliminary Study -- Capacitive and Resistive Electric Transfer Therapy: A Comparison of Operating Methods in Non-specific Chronic Low Back Pain -- Serum Impedance in Children with Recurrent Respiratory Infections -- Olfactory Response to Altitude Hypoxia: A Pilot Study During a Himalayan Trek -- The Impact of Change in Hospital Admissions When Primary Care Is Provided by a Single Primary Care Physician: A Cohort Study Among HMO Patients in Israel -- Risk of Falls in Patients Aged Over 65 in the Context of the Treatment Facility -- Anthropometric Indices as Long-Term Predictors of Diabetes in Impaired Fasting Glucose Metabolism: Findings in the PURE Study in Poland -- Cardiovascular Risk Factors Drive Impaired Fasting Glucose to Type 2 Diabetes: Findings After a 9-Year Follow-Up in the PURE Study in Poland -- Sleep-Disordered Breathing in Pregnancy.
    Abstract: This book embraces a comprehensive range of research across several disciplines, providing insights and fresh perspectives on clinical topics, emphasizing the integrative medical approach. The book also addresses an increasing role of artificial intelligence in the development of clinical methodologies, research, and patient-oriented care. The authors share expertise and experience in rehabilitation medicine whose healing-effects particularly depend on the interaction between the therapist and patient. Chapters present novel approaches in manual rehabilitative therapy of common painful and disabling neuromuscular ailments, exemplified but not limited to low back pain and migraine. The myofascial trigger point release therapy includes specific manipulations to muscles and connective tissue which reduce pain. Other chapters address the issues of providing long-range medical care to older adults burdened with chronic diseases, notably hypoxia-related pathologies and their sequalae, pointing to the advantages of care provided by a single primary care physician. Changing paradigm of care is essential in chronic atherosclerosis-based diseases like cardiovascular disorders or diabetes. Chapters provide results of international cohort studies on predictive factors for the long-range progress of such ailments based on anthropometric and lifestyle indicators. The book aims to meet the increasing interest and importance to patients of integrative health therapies. Medical rehabilitation and lifestyle changes increasingly gain scientific support in difficult-to-treat chronic conditions and should be integrated in a controlled manner into conventional medicine. The book is addressed to physiotherapists, medical scientists and clinicians, and allied healthcare professionals.
    Type of Medium: Online Resource
    Pages: VI, 109 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030996307
    Series Statement: Clinical and Experimental Biomedicine, 1375
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Education Data processing. ; Image processing Digital techniques. ; Computer vision. ; Anatomy. ; Biomedical engineering. ; Computer simulation. ; Biomedical Research. ; Computers and Education. ; Computer Imaging, Vision, Pattern Recognition and Graphics. ; Anatomy. ; Biomedical Engineering and Bioengineering. ; Computer Modelling.
    Description / Table of Contents: Chapter 1. Creating Interactive Three-Dimensional Applications to Visualise Novel Stent Grafts That Aid in the Treatment of Aortic Aneurysms -- Chapter 2. Using Confocal Microscopy to Generate an Accurate Vascular Model for Use in Patient Education Animation -- Chapter 3. Methods and applications of 3D Patient-Specific Virtual Reconstructions in Surgery -- Chapter 4. Proof of Concept for the Use of Immersive Virtual Reality in Upper Limb Rehabilitation of Multiple Sclerosis Patients -- Chapter 5. Virtual Wards: A Rapid Adaptation to Clinical Attachments in MBChB During the COVID-19 Pandemic -- Chapter 6. Artificial Intelligence: Innovation to Assist in the Identification of Sono-anatomy for Ultrasound-Guided Regional Anaesthesia -- Chapter 7. A Systematic Review of Randomised Control Trials Evaluating the Efficacy and Safety of Open and Endoscopic Carpal Tunnel Release -- Chapter 8. Exploring Visualisation for Embryology Education: A Twenty-First-Century Perspective -- Chapter 9. How Artificial Intelligence and Machine Learning Is Assisting Us to Extract Meaning from Data on Bone Mechanics? -- Chapter 10. Visual Communication and Creative Processes Within the Primary Care Consultation -- Chapter 11. Digital 2D, 2.5D and 3D Methods for Adding Photo-Realistic Textures to 3D Facial Depictions of People from the Past -- Chapter 12. Teaching with Cadavers Outside of the Dissection Room Using Cadaveric Videos -- Chapter 13. A Novel Cadaveric Embalming Technique for Enhancing Visualisation of Human Anatomy -- Chapter 14. Assessing the Impact of Interactive Educational Videos and Screencasts Within Pre-clinical Microanatomy and Medical Physiology Teaching.
    Abstract: This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualisation techniques and technologies for the historical and forensic settings. The chapters presented in this volume cover such a diverse range of topics, with something for everyone. We present here chapters on 3D visualising novel stent grafts to aid treatment of aortic aneuryms; confocal microscopy constructed vascular models in patient education; 3D patient specific virtual reconstructions in surgery; virtual reality in upper limb rehabilitation in patients with multiple sclerosis and virtual clinical wards. In addition, we present chapters in artificial intelligence in ultrasound guided regional anaesthesia; carpal tunnel release visualisation techniques; visualising for embryology education and artificial intelligence data on bone mechanics. Finally we conclude with chapters on visualising patient communication in a general practice setting; digital facial depictions of people from the past; instructor made cadaveric videos, novel cadaveric techniques for enhancing visualisation of the human body and finally interactive educational videos and screencasts. This book explores the use of technologies from a range of fields to provide engaging and meaningful visual representations of the biomedical sciences. It is therefore an interesting read for researchers, developers and educators who want to learn how visualisation techniques can be used successfully for a variety of purposes, such as educating students or training staff, interacting with patients and biomedical procedures in general.
    Type of Medium: Online Resource
    Pages: XVI, 343 p. 163 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030877798
    Series Statement: Advances in Experimental Medicine and Biology, 1356
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Environmental geography. ; Public health. ; Big data. ; Epidemiology. ; Geographical Information System. ; Integrated Geography. ; Public Health. ; Big Data. ; Epidemiology.
    Description / Table of Contents: Chapter 1-Building the analytic toolbox-from spatial analytics to spatial statistical inference with geospatial data -- Chapter 2-Spatial data integration to better represent pollutants for environmental health studies -- Chapter 3-Spatial health data analysis-data driven and model driven approaches. Chapter 4 -- Machine learning, big data and spatial tools-a combination to reveal complex facts that impact environmental health -- Chapter 5-Spatial aspects of seasonality and infectious diseases -- Chapter 6-Earth observation data and technology to model influenza epidemiology -- Chapter 7-Trend of geospatial technology in environmental health application-from public health to individual healthcare -- Chapter 8-Geospatial technology to analyze human well-being and its eco-social determinants -- Chapter 9-Spatial components of population health -- Chapter 10-Geospatial technology in medical geology -- Chapter 11-Geospatial technology in planning and operations of telehealth programs -- Chapter 12-Integrating GIS, toxicology, microbiology and geochemistry-a multidisciplinary integrated approach for better understanding the public health issues.
    Abstract: Over the last thirty years or so, there have been tremendous advancements in the area of geospatial health; however, somehow, two aspects have not received as much attention as they should have received. These are a) limitations of different spatial analytical tools and b) progress in making geospatial environmental exposure data available for advanced health science research and for medical practice. This edited volume addresses those two less explored areas of geospatial health with augmented discussions on the theories, methodologies and limitations of contemporary geospatial technologies in a wide range of applications related to human well-being and health. In 20 chapters, readers are presented with an up-to-date assessment of geospatial technologies with an emphasis on understanding general geospatial principles and methodologies that are often overlooked in the research literature. As a result, this book will be of interest to both newcomers and experts in geospatial analysis and will appeal to students and researchers engaged in studying human well-being and health. Chapters are presenting new concepts, new analytical methods and contemporary applications within the framework of geospatial applications in human well-being and health. The topics addressed by the various chapter authors include analytical approaches, newer areas of geospatial health application, introduction to unique resources, geospatial modeling, and environmental pollution assessments for air, water and soil. Although geospatial experts are expected to be the primary readers, this book is designed in such a way so that the public health professionals, environmental health scientists and clinicians also find it useful with or without any familiarity with geospatial analysis.
    Type of Medium: Online Resource
    Pages: XVIII, 417 p. 141 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030713775
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Statistics . ; Computer science Mathematics. ; Mathematical statistics. ; Functions of complex variables. ; Algorithms. ; Geographical Information System. ; Statistics in Engineering, Physics, Computer Science, Chemistry and Earth Sciences. ; Probability and Statistics in Computer Science. ; Several Complex Variables and Analytic Spaces. ; Algorithms.
    Description / Table of Contents: Chapter 1: Binary Variable Versus Binary Variable -- Chapter 2: Binary Variable Versus Rank Variable -- Chapter 3: Application of the Total Operating Characteristic -- Chapter 4: Categorical Variable Versus Categorical Variable -- Chapter 5: Application to Categorical Error Assessment with Sampling -- Chapter 6: Multiple Spatial Resolutions for Categorical Variables -- Chapter 7: Application to Categorical Temporal Change -- Chapter 8: Interval Variable Versus Interval Variable -- Chapter 9: Application to Interval Temporal Change -- Chapter 10: Indices of Agreement -- Chapter 11: Vector Variable Versus Vector Variable -- Chapter 12: Commandments to Avoid Deadly Sins.
    Abstract: Your government warns that 10% of your neighbors have a deadly contagious virus. The producer of a diagnostic test advertises that 90% of its tests are correct for any population. The test indicates that you have the virus. This book’s author claims your test has a 50% chance of being false, given your test’s result. Who do you believe? This book gives you insights necessary to interpret metrics that make a difference in life’s decisions. This book gives methods and software that are essential to analyse change and error. Change describes a phenomenon across time points. Error compares diagnoses with the truth. Other texts give insufficient attention to these topics. This book’s novel ideas dispel popular misconceptions and replace previous methods. The author uses carefully designed graphics and high school mathematics to communicate easily with college students and advanced scientists. Applications include but are not limited to Remote Sensing, Land Change Science, and Geographic Information Science. “A wide range of tools to aid understanding of land cover and its change has been used but scientific progress has sometimes been limited through misuse and misunderstanding. Professor Pontius seeks to rectify this situation by providing a book to accompany the researcher’s toolbox. Metrics That Make a Difference addresses basic issues of relevance to a broad community in a mathematically friendly way and should greatly enhance the ability to elicit correct information. I wish this book existed while I was a grad student.” – Giles Foody, Professor of Geographical Information Science, The University of Nottingham “Metrics That Make a Difference provides a comprehensive synthesis of over two decades of work during which Dr. Pontius researched, developed, and applied these metrics. The book meticulously and successfully guides the reader through the conceptual basis, computations, and proper interpretation of the many metrics derived for different types of variables. The book is not just a mathematical treatise but includes practical guidance to good data analysis and good science. Data scientists from many fields of endeavor will benefit substantially from Dr. Pontius’ articulate review of traditionally used metrics and his presentation of the innovative and novel metrics he has developed. While reading this book, I had multiple ‘aha’ moments about metrics that I shouldn't be using and metrics that I should be using instead.” – Stephen Stehman, Distinguished Teaching Professor, State University of New York.
    Type of Medium: Online Resource
    Pages: XXI, 117 p. 17 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030707651
    Series Statement: Advances in Geographic Information Science,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Environmental monitoring. ; Physical geography. ; Environment. ; Geographical Information System. ; Environmental Monitoring. ; Earth System Sciences. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1-Why this Topic? -- Chapter 2-Global Warming Impact on Earth Systems -- Chapter 3-The IPCC Reports on Global Warming and Land Changes -- Chapter 4.NOAA Operational Environmental Satellites for Earth Monitoring -- Chapter 5-New Remote Sensing Vegetation Health Technology -- Chapter 6-Cause of Climate Warming -- Chapter 7- Land Cover Changes from Intensive Climate Warming -- Chapter 8-Global Warming Crop Yield and Food Security -- Chapter 9-Remote Sensing Malaria During Global Warming -- Chapter 10-Malaria Performance Trend During 1981-2022 -- Chapter 11-Remote Sensing Drought Watch and Food Security -- Chapter 12-Has Drought Intensified During 1981-2021 Global Warming?
    Abstract: This book discusses the detrimental consequences of climate-related land changes over a 40-year period between 1981 and 2020, and focuses on how climate warming is deteriorating the agricultural system due to excessive heat, lack of moisture and more intensive and widespread droughts leading to a reduction of agricultural production. Most of the existing literature on the unfavourable consequences of global warming for land are based on a relatively short period of weather station data, covering local land areas with limited networks and monitoring parameters. These concerns have led to the use of satellite data, whose measurements are controlled by such vegetation characteristics as chlorophyll, carotenoids, moisture contents in the plants and temperature inside the vegetation community. Therefore, the discussion of this book is completely based on high-resolution global land surface measurements by the sensors on the National Oceanic and Atmospheric Administration’s (NOAA) operational afternoon polar-orbiting satellites. The book also focuses on understanding climate change impacts on land changes where humans are living, and combines biophysically-grounded methods and the 40-year data to develop models for monitoring large-scale Earth warming impacts on land and for timely prediction of climate consequences for humans. These 40-year trends in land characteristics will help to better inform the assessment of potential changes in the future and how to reach human sustainability. The book will of interest to scientists using satellite remote sensing to track climate change impacts on land over time, as well as students and researchers in climatology and environmental sustainability. .
    Type of Medium: Online Resource
    Pages: IX, 462 p. 159 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968106
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Geography. ; Computer programming. ; Geographical Information System. ; Geography. ; Programming Techniques.
    Description / Table of Contents: Chapter 1. Introduction to Scripting and Programming -- Chapter 2. Basics of programming—Variables, Operators, & Statements -- Chapter 3. Basics of programming—Control Structures -- Chapter 4. Basics of programming—Functions and Objects -- Chapter 5. Reading a Python Script -- Chapter 6. Debugging -- Chapter 7. Introduction to ArcPy -- Chapter 8. Basics of accessing data in ArcGIS -- Chapter 9. Rasters -- Chapter 10. Tables and Cursors -- Chapter 11. Vectors and Geometries -- Chapter 12. Mapping--symbologies -- Chapter 13. Mapping—layouts -- Chapter 14. Creating custom tools -- Chapter 15. Error Handling -- Chapter 16. Creating Custom Classes -- Chapter 17. Putting it all together -- Chapter 18. ArcPy for Web GIS using ArcGIS Online -- Chapter 19. Incorporating External Packages -- Chapter 20. Using Multiple Python Files -- Chapter 21. Developing a Custom Python Package.
    Abstract: This upper-undergraduate textbook teaches students programming in GIS using a mix of computer science theory and hands-on activities, with the aim of empowering students to understand fundamentals and apply their knowledge beyond the specific examples in the book. Each of the book’s twenty-one chapters integrates instructional material with exercises in ArcGIS Pro. In doing so, this book combines the strengths of workbooks and theoretical textbooks to provide a holistic and comprehensive text. Each chapter concludes with an unguided task that ensures students have learned the broader principles explained therein. In addition to its unique format, the book covers oft-neglected topics such as debugging, creating a program from scratch, and managing metadata. Section I starts with the principles of scripting and programming with Python. Section II introduces the ArcPy module and elements specific to ArcGIS Pro. This section focuses on data structures, and how they are used and implemented within Python. Section III uses the topic of algorithms to guide the student through creating tools to add functionality to ArcGIS Pro. The last section, Section IV, builds upon section III to guide the student to developing and sharing projects and Python packages to include external open-source code and share the Python code as an open-source package. This text will prepare students for a long-term ability to do GIS programming, whether in industry or academic research. This comes from the author’s observations of students who have learned GIS programming in one platform, such as VBA in ArcMap, struggle to apply that knowledge to a new platform, such as Python in ArcGIS Pro, because the content was presented too closely with a specific platform. The integration of exercises with conceptual content, along with the choice of chapter content, serves this goal of preparing students for working in a dynamic, rapidly changing technology field.
    Type of Medium: Online Resource
    Pages: XII, 267 p. 110 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084980
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 910.285
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Medical care. ; Quantitative research. ; Artificial intelligence Data processing. ; Health services administration. ; Bioinformatics. ; Biomedical Research. ; Health Care. ; Data Analysis and Big Data. ; Data Science. ; Health Care Management. ; Bioinformatics.
    Description / Table of Contents: 1. AI and Big Data for Intelligent Health: Promise and Potential -- 2. AI and Big Data for Cancer Segmentation, Detection and Prevention -- 3. Radiology, AI and Big Data: Challenges and Opportunities for Medical Imaging -- 4. Neuroradiology: Current Status and Future Prospects -- 5. Big Data and AI in Cardiac Imaging -- 6. Artificial Intelligence and Big data for COVID-19 Diagnosis -- 7. AI and Big Data for Drug Discovery -- 8. Blockchain of IoMT (BIoMT): A New Paradigm for COVID-19 Pandemic: Application, Architecture, Technology, and Security -- 9. AI and Big Data for Therapeutic Strategies in Psychiatry -- 10. Distributed Learning in Healthcare -- 11. Cybersecurity in Healthcare -- 12. Radiology and Radiomics: Towards oncology Prediction with IA and Big Data.
    Abstract: This book aims to present the impact of Artificial Intelligence (AI) and Big Data in healthcare for medical decision making and data analysis in myriad fields including Radiology, Radiomics, Radiogenomics, Oncology, Pharmacology, COVID-19 prognosis, Cardiac imaging, Neuroradiology, Psychiatry and others. This will include topics such as Artificial Intelligence of Thing (AIOT), Explainable Artificial Intelligence (XAI), Distributed learning, Blockchain of Internet of Things (BIOT), Cybersecurity, and Internet of (Medical) Things (IoTs). Healthcare providers will learn how to leverage Big Data analytics and AI as methodology for accurate analysis based on their clinical data repositories and clinical decision support. The capacity to recognize patterns and transform large amounts of data into usable information for precision medicine assists healthcare professionals in achieving these objectives. Intelligent Health has the potential to monitor patients at risk with underlying conditions and track their progress during therapy. Some of the greatest challenges in using these technologies are based on legal and ethical concerns of using medical data and adequately representing and servicing disparate patient populations. One major potential benefit of this technology is to make health systems more sustainable and standardized. Privacy and data security, establishing protocols, appropriate governance, and improving technologies will be among the crucial priorities for Digital Transformation in Healthcare.
    Type of Medium: Online Resource
    Pages: X, 251 p. 67 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031111990
    Series Statement: Integrated Science, 9
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Neurosciences. ; Biotechnology. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Biomedical Devices and Instrumentation. ; Neuroscience. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Scaffolds for promoting neural repair -- Chapter 2. Composites for nerve regeneration -- Chapter 3. Configurable models of the blood-brain barrier -- Chapter 4. Engineering nerve conduits -- Chapter 5. Flexible electronics for stem cell differentiation -- Chapter 6. Nanosensors for brain chemistry -- Chapter 7. Nanomaterials for imaging the brain ECS -- Chapter 8. Microfluidics for analysis of neuronal development -- Chapter 9. Multiple particle tracking measurements of extracellular matrix dysregulation -- Chapter 10. Bioresponsive nanomaterials for treatment of CNS disease -- Chapter 11. Redox regulation for controlling cell fate -- Chapter 12. Polymersome delivery of CRISPR-based therapies -- Chapter 13. Multifunctional polymers for targeted delivery -- Chapter 14. Theranostic nanomaterials for brain injury.
    Abstract: This contributed volume explores the ways in which researchers engineer new biomaterials for the challenging problems of the peripheral and central nervous systems. These biomaterials are uniquely positioned for use in creating in vitro models of injury and disease, testing therapeutic treatments, understanding neural development, and mapping the multi-scalar environment of the brain. This book informs readers from biology, chemistry, materials science, engineering, and neuroscience on cutting edge research in engineering technologies, from fundamental material development through pre-clinical studies. The book also highlights target applications in three areas of research: (1) engineering neural models and materials, (2) probing biological underpinnings of neurological function and disease, and (3) designing therapeutic and diagnostic treatments for neurological disease. .
    Type of Medium: Online Resource
    Pages: VIII, 353 p. 64 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031114090
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Life sciences. ; Cytology. ; Spectrum analysis. ; Biomedical Research. ; Life Sciences. ; Cell Biology. ; Spectroscopy.
    Description / Table of Contents: Chapter 1. The physical principles of light propagation and light-matter interactions -- Chapter 2. Design, alignment and usage of infinity-corrected microscope -- Chapter 3. Epifluorescence Microscopy -- Chapter 4. Basic digital image design, processing, analysis, management, and presentation -- Chapter 5. Confocal Microscopy -- Chapter 6. Live-cell Imaging: A Balancing Act Between Speed, Sensitivity and Resolution -- Chapter 7. Structured Illumination Microscopy -- Chapter 8. Stimulated Emission Depletion Microscopy -- Chapter 9. Two-Photon Imaging -- Chapter 10. Modern microscopy image analysis: quantifying colocalization on a mobile device -- Chapter 11. Spinning Disk Microscopy -- Chapter 12. Light Sheet Fluorescence Microscopy -- Chapter 13. Localization microscopy: a review of the progress in methods and applications.
    Abstract: This textbook is an excellent guide to microscopy for students and scientists, who use microscopy as one of their primary research and analysis tool in the laboratory. The book covers key microscopy principles and explains the various techniques such as epifluorescence microscopy, confocal/live cell imaging, SIM/light sheet microscopy, and many more. Easy-to-understand protocols provide helpful guidance for practical implementation in various commercially available imaging systems. The reader is introduced to histology and further be guided through advanced image acquisition, classification and analysis. The book is written by experienced imaging specialists from the UK, other EU countries, the US and Asia, and is based on advanced training courses for master students and PhD students. Readers are not expected to be familiar with imaging and microscopy technologies, but are introduced to the subject step by step. This textbook is indented for biomedical and medical students, as well as scientists and postdocs who want to acquire a thorough knowledge of microscopy, or gain a comprehensive overview of modern microscopy techniques used in various research laboratories and imaging facilities. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 324 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031044779
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Biotechnology. ; Molecular biology. ; Nanotechnology. ; Bioethics. ; Biomedical Research. ; Biomedical Engineering and Bioengineering. ; Biotechnology. ; Molecular Biology. ; Nanotechnology. ; Bioethics.
    Description / Table of Contents: The advent of Medical Biotechnology -- Biotechnology in Medicine: Fundamentals -- Biotechnology in Medicine: Advances-I -- Biotechnology in Medicine: Advances-II -- Analytical Techniques in Medical Biotechnology -- Immunology in Medical Biotechnology -- Epigenetics and Medical Biotechnology -- Stem Cell Technology in Medical Biotechnology -- Pharmaceutical Biotechnology -- Diagnostic and Therapeutic Biotechnology -- Nanotechnology and Nanomedicine -- Laboratory Protocols in Medical Biotechnology-I -- Laboratory Protocols in Medical Biotechnology-II -- Ethics and Medical Biotechnology -- Career and opportunities in Medical Biotechnology -- Index.
    Abstract: This book serves as an introduction to the concepts of medical biotechnology, with great details about fundamentals and early disciplines of study as well as emerging fields and the latest research. The book follows a chronological order from the earliest discoveries and breakthroughs of medical biotechnology to the latest areas of study. The book contains up-to-date citations for each chapter and section, which makes it easy for the reader to understand the concept and also to follow the latest developments in the particular area. It is an ideal book for undergraduate and graduate students who aspire to derive basic knowledge and are also keen on learning about the latest advancements in the field of medical biotechnology. .
    Type of Medium: Online Resource
    Pages: XII, 459 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030985547
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Neurosciences. ; Public health. ; Bioethics. ; Clinical medicine Research. ; Biomedical Research. ; Neuroscience. ; Public Health. ; Bioethics. ; Clinical Research.
    Description / Table of Contents: Introduction on Integrated Science: Multidisciplinarity and Interdisciplinarity in Health -- Cognitive Sciences as a Naturalistic Model of Interdisciplinary Approaches -- The Aesthetics of Science from the Viewpoint of Neuroscience -- Neuroscience and Quantum Physics Aspect of Human Brainwaves -- Modern Psychiatry: Confluence of Mind, Science, and Society -- Schizophrenia: A Disorder of Timing and Sensorimotor Integration during Decision-making -- Getting to Know Ourselves Through Recognizing Ourselves in Others: Neuroanatomy of Empathy in a Social Neuroscientific Model -- Why People Make Irrational Choices About Their Health? -- Adherence to Treatment: At the Interface of Biological, Medical, and Social Sciences -- Social Cognition and Food Decisions in Obesity -- Nuclear Medicine: A Transdisciplinary Field to Integrate Formal, Physical, Biological, and Medical Sciences -- Beyond the Borders of Dentistry: Interprofessional and Interdisciplinary Approach to Oral Health Promotion -- Drug Discovery in Big Pharma: Where “Birds” and “Fish” Collaborate to Find New Medicines -- A Phenomenological Analysis of the Pandemic: Philosophy and Life -- Engineering, Environment, and Health: Why interdisciplinarity matters? -- Super-spreading in Infectious Diseases: A Global Challenge for All Disciplines -- Possibility of Changes in Travel Behavior as a Consequence of the Pandemic and Teleworking -- Bringing the Two Cultures of the Arts and Sciences Together in Complex Health Interventions -- Thinking Deeper, Wider, Further: Visual Thinking for the Pandemic 3.0 and the Game-Changing Pathways ahead -- The Clinical Benefits of Art Therapy: Definition, History, and Outcomes with a Focus on Music Therapy -- When Combining Arts and Sciences Assists Medical Devices Uses: DeafSpace and Cochlear Implants -- Art, Medicine, and Public Health: Synergizing Humanistic and Medical Strategies in Managing a Pandemic -- Big Data and Artificial Intelligence for E-Health -- Artificial Intelligence in the Medical Context: Who Is the Agent in Charge? -- Ethical Deliberation on AI-Based Medicine -- Towards an Integrative and Holistic Approach to the Discipline of Health Informatics -- Integrated, Multidisciplinary, and Interdisciplinary Medical Education -- Giving Voice to Social Values in Achieving Universal Health Coverage -- Discrimination in Medical Research Sampling: Recommendations and Applications to Psychology -- Integrated Science 2050: Multidisciplinarity and Interdisciplinarity in Health.
    Abstract: The contributed volume "Multidisciplinarity and Interdisciplinarity in Health" is a health-centered volume of the Integrated Science Book series. Lack of confidence, lack of expertise, complexities of healthcare, the confusing nature of healthcare environments, and lack of organization and standardization can become obstacles to successful communication. This volume establishes how extensive is the interface between formal sciences and medical sciences on health-related issues. The book provides an overview of the value of the integration of formal, biological, and medical sciences and related products, i.e., health informatics and biomedical engineering, to frame a holistic approach to health systems, healthcare, medical practice, drug discovery, and medical device design. The book also focuses on innovative solutions to the most critical issues of different health crisis, including obesity, infectious outbreaks, and cancer that can be found by using an integrative approach. It also contains the fascinating crossroads between medical sciences, physics, and mind that is discussed from multiple perspectives on cognition, neuroscience, and psychiatry. These multidisciplinary considerations will expand the concepts of creativity, leadership, aesthetics, empathy and mental health. .
    Type of Medium: Online Resource
    Pages: XVI, 729 p. 168 illus., 138 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968144
    Series Statement: Integrated Science, 6
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Materials Microscopy. ; Crystallography. ; Nanotechnology. ; Materials Analysis. ; Imaging systems. ; Biomedical Research. ; Microscopy. ; Crystallography and Scattering Methods. ; Nanotechnology. ; Characterization and Analytical Technique. ; Imaging Techniques.
    Description / Table of Contents: A Beginner’s Guide to Different Types of Microscopes -- Principles of Light and Fluorescence Microscopy -- Confocal and Multiphoton Microscopy -- Scanning Probe Microscopy: tipping the path towards atomic visions -- Atomic Force Microscopy - An Advanced Imaging Technique: From Molecules to Morphologies -- Exploring the microcosm at atomic precision using Atomic Force Microscopy -- Scanning Electron Microscopy (SEM): Learning to generate and interpret the topographical aspects of materials -- Recent updates on methods, applications, and practical uses of scanning electron microscopy in various life sciences -- Transmission electron microscopy - A powerful and novel scientific technique with nanoscale resolution for characterization of materials -- Preparation of Biological Samples for SEM: Techniques and Procedures -- Index.
    Abstract: This book covers fundamental microscopic techniques for Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), and other microscopic tools. It provides step-by-step instructions and explanations of the basic fundamental concepts and mechanisms and guides the reader on resolving queries related to taking and analyzing microscopy images. The latest advancements and developments in microscopic equipment are described. Theoretical background on microscopy is also provided to enhance the reader’s understanding of microscopy techniques and tools. Microscopic Techniques for the Non-Expert is an ideal book for undergraduate and postgraduate students, as well as researchers with a background in environmental science, materials science, biomedicine, engineering, or bio-nanotechnology.
    Type of Medium: Online Resource
    Pages: XII, 247 p. 127 illus., 100 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030995423
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Radiology. ; Biotechnology. ; Medical sciences. ; Biomedical Research. ; Radiology. ; Biotechnology. ; Health Sciences.
    Description / Table of Contents: 1. Introduction -- 2. Tracer technique in basic research -- 3. Tracer technique in applied research -- 4. Literature cited.
    Abstract: This book serves as a practical guide and a manual on the application of isotopic tracers in understanding the cellular processes (e.g. molecular interactions, protein synthesis) in growth, development, and disease conditions. The techniques described in the book have been carefully chosen to underscore the role and relevance of isotopic tracers in the identification of molecular targets and mechanisms, and preclinical validation of potential therapeutics. This book is intended to be a valuable resource to non-experts that may include students, researchers, educators/teachers, and others who have an interest to understand the application of isotopic tracers in research. Each chapter includes a background, an outline of the method and underlying principles, and a detailed step-wise protocol. To augment the clarity and intellectual grasp, the chapters also include relevant illustrations and study questions. More importantly, the book covers techniques involving radioactive as well as non-radioactive tracers to expand the scope of isotopes in preclinical research including basic and applied science.
    Type of Medium: Online Resource
    Pages: XIII, 66 p. 19 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030997007
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Human physiology. ; Biotechnology. ; Ultrasonics. ; Biomedical Research. ; Human Physiology. ; Biotechnology. ; Ultrasonics.
    Description / Table of Contents: Preface (Claus Glüer) -- Chapter 1. Introduction (Quentin Grimal and Pascal Laugier) -- Part I: Ultrasound Methods for Skeletal Status Clinical Assessment -- Chapter 2. Quantitative Ultrasound (QUS) in the Management of Osteoporosis and Assessment of Fracture Risk: An Update (Didier Hans, Antoine Metrailler, Elena Gonzalez Rodriguez, Olivier Lamy, Enisa Shevroja) -- Chapter 3. Clinical devices for bone assessment (Kay Raum and Pascal Laugier) -- Chapter 4. Axial transmission – Techniques, devices and clinical results (Nicolas Bochud and Pascal Laugier) -- Chapter 5. Signal processing techniques applied to axial transmission ultrasound (Tho N.H.T. Tran, Kailiang Xu, Lawrence H. Le, and Dean Ta) -- Chapter 6. Ultrasonic Assessment of Cancellous Bone Based on the Two-Wave Phenomenon (Katsunori Mizuno, Yoshiki Nagatani, Isao Mano) -- Chapter 7. Pulse-echo Measurements of Bone Tissues. Techniques and Clinical Results at the Spine and Femur (Delia Ciardo, Paola Pisani, Francesco Conversano, Sergio Casciaro) -- Chapter 8. Scattering in Cancellous Bone (Keith Wear) -- Chapter 9. Ultrasound Scattering in Cortical Bone (Yasamin Karbalaeisadegh and Marie Muller) -- Chapter 10. Single-sided ultrasound imaging of the bone cortex: anatomy, tissue characterization and blood flow (Guillaume Renaud and Sébastien Salles) -- Chapter 11. Ultrasound Computed Tomography (Philippe Lasaygues, Luis Espinosa, Simon Bernard, Philippe Petit, Régine Guillermin) -- Part II: Ex vivo Measurement of Bone Material Properties: New Methods and Data -- Chapter 12. Measurement of Cortical Bone Elasticity Tensor with Resonant Ultrasound Spectroscopy (Simon Bernard, Xiran Cai and Quentin Grimal) -- Chapter 13. Documenting the anisotropic stiffness of hard tissues with resonant ultrasound spectroscopy (Xiran Cai, Simon Bernard, Quentin Grimal) -- Chapter 14. Assessing the elasticity of child cortical bone (Cécile Baron, Hélène Follet, Martine Pihioux, Cédric Payan, and Philippe Lasaygues) -- Chapter 15. Piezoelectric and Opto-Acoustic Material Properties of Bone (Atsushi Hosokawa and Mami Matsukawa) -- Part III: Emerging applications of Bone Quantitative Ultrasound -- Chapter 16. 3D Ultrasound Imaging of the Spine (Yong Ping Zheng and Timothy Tin Yan Lee) -- Chapter 17. Ultrasonic Evaluation of the Bone-Implant Interface (Yoann Hériveaux, Vu-Hieu Nguyen, Guillaume Haïat) -- Chapter 18. Adaptive ultrasound focusing through the cranial bone for non-invasive treatment of brain disorders (Thomas Bancel, Thomas Tiennot, Jean-François Aubry) -- Chapter 19. GuidedWaves in the Skull (Héctor Estrada and Daniel Razansky) -- Index.
    Abstract: Many significant achievements in new ultrasound technologies to measure bone and models to elucidate the interaction and the propagation of ultrasonic waves in complex bone structures have been reported over the past ten years. Impaired bone remodeling affects not only the trabecular compartment but also the cortical one. Despite the crucial contribution of the cortical structure to the whole bone mechanical competence, cortical bone was understudied for a long time. A paradigm shift occurred around 2010, with a special focus placed on the importance of cortical bone. This has sparkled a great deal of interest in new ultrasound techniques to assess cortical bone. While our book ‘Bone Quantitative Ultrasound’ published in 2011 emphasized techniques to measure trabecular bone, this new book is devoted for a large part to the technologies introduced recently to measure cortical bone. These include resonant ultrasound spectroscopy, guided waves, scattering, and pulse-echo and tomography imaging techniques. Instrumentation, signal processing techniques and models used are detailed. Importantly, the data accumulated in recent years such as anisotropic stiffness, elastic engineering moduli, compression and shear wave speeds of cortical bones from various skeletal sites are presented comprehensively. A few chapters deal with the recent developments achieved in quantitative ultrasound of trabecular bone. These include (i) scattering-based approaches and their application to measure skeletal sites such as the spine and proximal femur and (ii) approaches exploiting the poro-elastic nature of bone. While bone fragility and osteoporosis are still the main motivation for developing bone QUS, this Book also includes chapters reporting ultrasound techniques developed for other applications of high interest such as 3-D imaging of the spine, assessment of implant stability and transcranial brain imaging. This book, together with the book ‘Bone Quantitative Ultrasound’ published in 2011 will provide a comprehensive overview of the methods and principles used in bone quantitative ultrasound and will be a benchmark for all novice or experienced researchers in the field. The book will offer recent experimental results and theoretical concepts developed so far and would be intended for researchers, graduate or undergraduate students, engineers, and clinicians who are involved in the field. The book should be considered as a complement to the first book publisher in 2011, rather than a second edition, in the sense that basic notions already presented in the first book are not repeated.
    Type of Medium: Online Resource
    Pages: X, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030919795
    Series Statement: Advances in Experimental Medicine and Biology, 1364
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Art Study and teaching. ; Biomedical engineering. ; Philosophy. ; Economic sociology. ; Biomedical Research. ; Creativity and Arts Education. ; Biomedical Engineering and Bioengineering. ; Philosophy. ; Economic Sociology.
    Description / Table of Contents: 1 Introduction on Integrated Science: Transdisciplinary across the Different Disciplines -- 2 Chaos Theoretical Explanation to Each Development of Evolution Theory, Psychology, Physics, and Philosophy -- 3 Managerial Problems and Cultural Heritage in Information Technology -- 4 On the Essential Unity of Mathematics, Science, and Art: The Justice Evaluation Function and the Golden Number -- 5 Integration of Film Theory and Studies with Neuroscience -- 6 Systems View in Engineering Research -- 7 Molecular Dynamics Simulations: Concept, Methods, and Applications -- 8 The World Big Challenges Faced by Nanoscience: Examples of How Integrated Science Can Save the World -- 9 The Kaleidoscopic Image as an Intersection between Art and Science: From Microscopic Forms to Cosmological Models -- 10 Disruptions and Competitive Strategies in the Automotive Industry -- 11 Macroeconomics: From Equilibrium Settings to Multi-Agent Worlds -- 12 A Multi-level Perspective to Biosimilars Development: Pathways Towards Incremental Innovation in the Health Bioeconomy -- 13 A 2020s Marketing Taxonomy for Augmented Reality Customer Experience -- 14 Can Viral Marketing Content Spread according to the Rumour Formula? -- 15 Exaptation as a Design Strategy for Resilient Communities -- 16 Ecosystem management and climate-smart agriculture -- 17 A new generation of shrimp aquaculture for sustainability and resilience of future green cities -- 18 Public Understanding of Geoethics Dilemmas: A Case Study on Lithium Exploitation -- 19 Creative Approaches for Mitigating Environmental Challenges: A Cosmopolitan Localism Perspective -- 20 Landscape: A Holistic Approach to Space -- 21 Integrated Approaches to Land Management -- 22 Archaeology as an Interdisciplinary Science at the Cross-Roads of Physical, Chemical, Biological, and Social Sciences: New Perspectives and Research -- 23 Biomimicry in Architecture: From Theory to Practice -- 24 Ecodemocracy in Practice: Examples of Forestry and Food Production -- 25 Semantic Analyses of Hilary Putnam’s Twin Earth (ft. TE Diagram) -- 26 Sport Sciences: An Ideal Field of Play for Integrated Knowledges -- 27 Single Valued Neutrosophic Set: An Overview -- 28 Technology Assessment Integrated research for scientific policy advice -- 29 The Artistic and Scientific Nature of Protein Structure: A Historical Overview -- 30 The Art and Science of Biomimicry – Abstracting Design Principles from Nature -- 31 The Phenomenon of Meeting in Art: A Transdisciplinary Approach -- 32 The Phenomenon of Meeting in Art: A Transdisciplinary Approach.
    Abstract: This contributed volume book aims at discussing transdisciplinary approaches to address common problems. By working transdisciplinarily, researchers coming from different disciplines can work jointly using a shared conceptual framework bringing together disciplinary-specific theories and concepts. There are numerous barriers that can obstruct effective communication between different cultures, communities, religions and geographies. This book shows that through bringing together different disciplines, researchers not only can surpass these barriers but can effectively produce new venues of thought that can positively affect the development and evolution of research and education. The book discusses new and emerging applications of knowledge produced by transdisciplinary efforts and covers the interplay of many disciplines, including agriculture, economics, mathematics, engineering, industry, information technology, marketing, nanoscience, neuroscience, space exploration, human-animal relationships, among others. Consequently, it also covers the relationship between art and science, as one of the most remarkable transdisciplinary approaches that paves the way for new methods in engineering, design, architecture and many other fields. .
    Type of Medium: Online Resource
    Pages: XIII, 741 p. 239 illus., 193 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030946517
    Series Statement: Integrated Science, 5
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Clinical medicine Research. ; Public health. ; Political planning. ; Social medicine. ; Biomedical Research. ; Translational Research. ; Clinical Research. ; Public Health. ; Policy Formulation. ; Health, Medicine and Society.
    Description / Table of Contents: 1. Introduction -- Part I Transforming Research with Broad Engagement -- 2. The Transformative Power of Broadly Engaged Team Science: A Moth-er’s Quest to Understand PXE -- 3. Broadly Engaged Team Science in Neonatal Research -- 4. Patient Advocates in Cancer Care: A Rich Tradition and Evolving Role -- 5. National Kidney Foundation Patient Network -- 6. Broadly Engaged Team Science Comes to Life in a Design Lab -- 7. Tufts Center for the Study of Drug Development Employs Broadly Engaged Team Science to Explore the Challenges of Pharmaceutical Research and Development -- Part II. Integrating Communities and Stakeholders into Broadly Engaged Team Science -- 8. Social Movements and Stakeholder Engagement -- 9. A Basic Scientist’s Journey: Engaging Public Stakeholders Through Civic Science -- 10. Lessons in Public Involvement from Across the Pond -- 11. Leveling the Playing Field for Community Stakeholders: Examining Practices to Improve Engagement and Address Power Dynamics -- 12. A Theory of Stakeholder-driven Community Diffusion -- 13. Monitoring and Evaluation of Stakeholder Engagement in Health Research -- Part III. Applying Broadly Engaged Team Science: Case Studies -- 14. Insiders and Outsiders: A Case Study of Fostering Research Partnerships between Academic Health Centers and Corrections Institutions -- 15. Responding to the Community: HOPE (Healthy Outcomes from Positive Experiences) -- 16. Students as Key Collaborators in Tackling Early Stage Research Ideas -- 17. Engaging Stakeholders to Decrease Study Start-up Delays -- 18. Health Literacy and Broadly Engaged Team Science: How One Study Team Used Plain Language Principles to Share Findings with Affected Communities -- 19. Utilizing Patient Navigators to Promote Equitable and Accountable Research -- 20. Asian American Research in the Post-Atlanta Era: Driving Community-engaged Research That Is More Meaningful, Responsive, and Actionable for Local Communities -- 21. Stakeholder Engagement in Predictive Model Development for Clinical Decision Support -- Part IV. Creating an Institutional Environment of Support for Broadly Engaged Team Science -- 22. Research Administration Practices for Proposal Development and Post-Award Management of Stakeholders and Community Participants -- 23. Starting Off Right: Supporting Community Involvement in the Evaluation of Research Proposals -- 24. Role of Broadly Engaged Team Science in the Inclusion of Minority Populations as Research Participants and in All Roles on Research Teams -- 25. Rewarding Team Science in Tenure and Promotion Practices: An Operational Imperative for the Academic Research Enterprise of the 21st Century -- Epilogue.
    Abstract: Despite the large U.S. investment in health science, and the vast and growing body of peer-reviewed research findings it has produced, a compelling body of evidence suggests that research too often has been slow, inefficient, and fallen short of desired impacts on health. A key question is how research might be changed to be more innovative, less wasteful, and more responsive to unmet health needs. One emerging response within clinical and translational science is to advance an approach that attempts to close the gap between research scientists and key stakeholders; the individuals and groups responsible for or affected by health-related decisions. Broadly engaged team science promises to support this aim by transforming the gold standard, multi-disciplinary team science, to include key stakeholders in activities across the research spectrum. These new roles and responsibilities range from generating research questions to implementing research projects, to aiding in the translation of discoveries from the laboratory to the community. A transition to broadly engaged team science reflects the idea that inclusivity and a diversity of perspectives are necessary to achieving progress in addressing complex health issues while representing a new benchmark for ethical research practice. This is one of the first collections of papers describing how clinical and translational science researchers are defining and implementing new research practices, and the successes and challenges involved. This book represents a first and critical step towards organizing knowledge of broadly engaged team science and advancing the development of evidence-based practices. Written in an accessible style, this book is intended to highlight the breadth of broadly engaged team science within one community, motivate researchers and stakeholders to build inclusive teams, bring rigor to often informal stakeholder engagement research practices and encourage people to think more broadly about the development of scientific knowledge. It includes examples of multi-disciplinary, broadly engaged team science projects, the perspectives of academic leaders about the changes needed to encourage scientists to conduct broadly engaged team science, and a resource directory.
    Type of Medium: Online Resource
    Pages: XV, 260 p. 25 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030830281
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Internal medicine. ; Biomedical Research. ; Internal Medicine.
    Description / Table of Contents: Discovery and Overview of Par-4 -- Par-4 in cell cycle regulation -- Conformational studies of the Par-4 C-terminal Domain -- Structural analysis of Par-4 and crystallographic analysis of the regulatory domain -- Regulation of Par-4 by Ubiquitinases -- REGULATION OF PAR-4 FUNCTION BY PHOSPHORYLATION -- Role of Par-4 in GRP78 translocation -- PAR-4 in the regulation of stem cell death and embryo development -- RASSF2 and the PAR-4 connection -- Regulation of tumor suppressor Par-4 by ceramide -- PAWR as a direct SRC-1/HOXC11 suppression target -- Index.
    Abstract: Par-4 is a tumor suppressor protein first discovered and identified in 1993 by Dr. Vivek Rangnekar’s laboratory in prostate cancer cells undergoing apoptosis. Par-4 (later also known as PAWR) is a naturally occurring tumor suppressor. Studies have indicated that Par-4 selectively induces apoptosis in cancer cells while leaving normal, healthy, cells unaffected. Mechanisms contributing to the cancer-selective action of Par-4 have been associated with protein kinase A activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. Par-4 is downregulated, inactivated or mutated in diverse cancers. This first of two volumes will be the first on the market on the topic of Par-4, and will provide the opportunity for researchers to discuss the future direction of studies, broaden the scope of research, and contribute a more complete understanding of the molecule’s structural features, key functional domains, regulation and relevant basic and clinical/translational facets.
    Type of Medium: Online Resource
    Pages: X, 323 p. 84 illus., 81 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030735722
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Medical microbiology. ; Biomedical Research. ; Biomedical Research. ; Medical Genetics. ; Medical Microbiology.
    Description / Table of Contents: 1. Epithelial-mesenchymal transition and cancer stem cells -- 2. The transcription factors Zeb1 and Snail induce cell malignancy and can-cer stem cell phenotype in prostate cells, increasing androgen synthesis ca-pacity and therapy resistance -- 3. ERBB signaling pathway in cancer stem cells -- 4. Functional and molecular characters of cancer stem cells through devel-opment to establishment -- 5. Microenvironment in cancer stem cells -- 6. Cancer stem cells contribute to drug resistance in multiple different ways -- 7. Abnormal glycosylation in cancer cells and cancer stem cells as a thera-peutic target.
    Abstract: This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.
    Type of Medium: Online Resource
    Pages: XIV, 156 p. 23 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031129742
    Series Statement: Advances in Experimental Medicine and Biology, 1393
    DDC: 610.72
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Property. ; Common law. ; Industries. ; Economic geography. ; Geographical Information System. ; Common Property and Land Law. ; Industries. ; Economic Geography.
    Description / Table of Contents: Chapter 1 -- Brief history of "the beach" in Florida. Chapter 2 -- The legal geography of the beach. Chapter 3 -- The value of the property on/near the beach, despite natural hazard risk. Chapter 4 -- Capturing the beach experience. Chapter 5 -- Assessing public space along Florida beaches: NW FL case study. Chapter 6 -- Sketch mapping accessibility. Chapter 7 -- Explicit territoriality: good/bad fences. Chapter 8 -- Implied territoriality: good/bad neighbors. Chapter 9 -- Mapping the potential of conflict: transboundary viewsheds. Chapter 10 -- Conclusion: bringing it all together. .
    Abstract: This book offers a theoretical and practical exploration of the beach as space and place (i.e. territoriality) through three disciplinary lenses (Political Science, Geography, Art), utilizing the lens of territoriality and field-based participant cartographic mapping to understand better the ways in which the developed shoreline in Florida is territorialized. The book approaches the complex topic of territoriality on Florida’s beaches from two novel but related methods: participatory mapping/cartography and performance art. Both methods involve participants interacting with, perceiving, and ultimately representing feelings about a place. One method captures those feelings through the medium of the cartographic product (or a map), while the other leads to a set of symbols (flags), performance (actions in place) and visceral record (photography, sound, and journaling). Readers will gain insight into the role of political systems, ideological climates, local culture (including diverse cultures throughout the Florida state territory), and environmental history and challenges in shaping territoriality. The book will be of interest to a wide array of scholars working in coastal and land use planning topics at the intersection of geography, political science and art, including urban planners, land managers, and associated stakeholders dealing with ongoing tensions between private and public property rights on and near beaches.
    Type of Medium: Online Resource
    Pages: XIV, 100 p. 39 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030973155
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Cartography. ; Physical geography. ; Geographical Information System. ; Cartography. ; Earth System Sciences.
    Description / Table of Contents: Chapter 1. About this book -- Part I. Concepts, data and validation -- Chapter 2. Land Use Cover mapping, modelling and validation. A background -- Chapter 3. Validation of Land Use Cover maps: a guideline -- Chapter 4. Land Use Cover Datasets: a review -- Part II. Data access and visualization -- Chapter 5. Visualization and communication of LUC data -- Chapter 6. Sample data for thematic accuracy assessment in QGIS -- Part III. Tools to validate Land Use Cover maps: a review -- Chapter 7. Basic and Multiple-Resolution Cross Tabulation to validate Land Use Cover maps -- Chapter 8. Metrics based on a Cross-Tabulation matrix to validate Land Use Cover maps -- Chapter 9. Pontius Jr. methods based on a Cross Tabulation matrix to validate Land Use Cover maps -- Chapter 10. Validation of soft maps produced by a Land Use Cover Change model -- Chapter 11. Spatial metrics to validate Land Use Cover maps -- Chapter 12. Advanced pattern analysis to validate Land Use Cover maps -- Chapter 13. Geographically Weighted methods to validate Land Use Cover maps -- Part IV. Land Use Cover datasets: a review -- Chapter 14. Global general Land Use Cover datasets with a single date,- Chapter 15. Global general Land Use Cover datasets with a time series of maps -- Chapter 16. General Land Use Cover datasets for Europe -- Chapter 17. General Land Use Cover datasets for Africa -- Chapter 18. General Land Use Cover datasets for America and Asia -- Chapter 19. Global thematic Land Use Cover datasets characterizing vegetation covers -- Chapter 20. Global thematic Land Use Cover datasets characterizing agricultural covers -- Chapter 21. Global thematic Land Use Cover datasets characterizing artificial covers -- Chapter 22. Supra-national thematic Land Use Cover datasets.
    Abstract: This open access book represents a comprehensive review of available land-use cover data and techniques to validate and analyze this type of spatial information. The book provides the basic theory needed to understand the progress of LUCC mapping/modeling validation practice. It makes accessible to any interested user most of the research community's methods and techniques to validate LUC maps and models. Besides, this book is enriched with practical exercises to be applied with QGIS. The book includes a description of relevant global and supra-national LUC datasets currently available. Finally, the book provides the user with all the information required to manage and download these datasets.
    Type of Medium: Online Resource
    Pages: XIV, 462 p. 273 illus., 226 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030909987
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Quantitative research. ; Environmental sciences Mathematics. ; Database management. ; Geography. ; Geographical Information System. ; Data Analysis and Big Data. ; Mathematical Applications in Environmental Science. ; Database Management System. ; Geography.
    Description / Table of Contents: Part A Basics and Computer Science: -- Modeling of Geographic Information -- Mathematics and Statistics -- Databases -- Encoding of Geographic Information -- Big Data Analytics -- Part B Geographic Information: -- Geographic Information Systems (GIS) -- Change Detection -- Geodesy -- Data Acquisition in Geographic Information Systems -- Remote Sensing -- Surveying -- Geometry and Topology -- Cartography -- Geospatial Metadata -- Standardization of Geographic Information -- Geospatial Web Services -- Geosemantic Interoperability and the Geospatial Semantic -- Registration of Geospatial Information Elements -- Security for Open Distributed Geospatial Information Systems -- Part C Applications: -- Cadastre -- Building Information Modeling -- Location Based Services -- Marine Geographic Information Systems -- Geographic Information Systems in Agriculture -- Geographic Information Systems in Defense -- Geographic Information Systems for Transportation -- Geology -- Geographic Information Systems in Energy and Utilities -- Geographic Information Systems in Health and Human Services -- Open Source Geographic Information Systems -- Smart Cities.
    Abstract: This handbook provides an exhaustive, one-stop reference and a state-of-the-art description of geographic information and its use. This new, substantially updated edition presents a complete and rigorous overview of the fundamentals, methods and applications of the multidisciplinary field of geographic information systems. Designed to be a useful and readable desk reference book, but also prepared in various electronic formats, this title allows fast yet comprehensive review and easy retrieval of essential reliable key information. The Springer Handbook of Geographic Information is divided into three parts. Part A, Basics and Computer Science, provides an overview on the fundamentals, including descriptions of databases and encoding of geographic information. It also covers the underlying mathematical and statistics methods and modeling. A new chapter exemplifies the emerging use and analysis of big data in a geographic context. Part B offers rigorous descriptions of gathering, processing and coding of geographic information in a standardized way to allow interoperable use in a variety of systems; from traditional methods such as geodesy and surveying to state-of-the-art remote sensing and photogrammetry; from cartography to geospatial web services. Discussions on geosemantic interoperability and security of open distributed geospatial information systems complete the comprehensive coverage. The final part describes a wide array of applications in science, industry and society at large, such as agriculture, defense, transportation, energy and utilities, health and human services. The part is enhanced by new chapters on smart cities and building information modeling, as well as a complete overview of the currently available open-source geographic information systems. Using standardized international terminology, in accordance with ISO/TC 211 and INSPIRE, this handbook facilitates collaboration between different disciplines and is a must have for practitioners and new comers in industry and academia.
    Type of Medium: Online Resource
    Pages: XXXIV, 969 p. 620 illus. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030531256
    Series Statement: Springer Handbooks,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Data mining. ; Cooperating objects (Computer systems). ; Machine learning. ; Computational intelligence. ; Geographical Information System. ; Data Mining and Knowledge Discovery. ; Cyber-Physical Systems. ; Machine Learning. ; Computational Intelligence.
    Abstract: This book is the proceeding of the 1st International Conference on Distributed Sensing and Intelligent Systems (ICDSIS2020) which will be held in The National School of Applied Sciences of Agadir, Ibn Zohr University, Agadir, Morocco on February 01-03, 2020. ICDSIS2020 is co-organized by Computer Vision and Intelligent Systems Lab, University of North Texas, USA as a scientific collaboration event with The National School of Applied Sciences of Agadir, Ibn Zohr University. ICDSIS2020 aims to foster students, researchers, academicians and industry persons in the field of Computer and Information Science, Intelligent Systems, and Electronics and Communication Engineering in general. The volume collects contributions from leading experts around the globe with the latest insights on emerging topics, and includes reviews, surveys, and research chapters covering all aspects of distributed sensing and intelligent systems. The volume is divided into 5 key sections: Distributed Sensing Applications; Intelligent Systems; Advanced theories and algorithms in machine learning and data mining; Artificial intelligence and optimization, and application to Internet of Things (IoT); and Cybersecurity and Secure Distributed Systems. This conference proceeding is an academic book which can be read by students, analysts, policymakers, and regulators interested in Distributed Sensing, Smart Network approaches, Smart Cities, IoT Applications, and Intelligent Applications. It is written in plain and easy language, and describes new concepts when they appear first so that a reader without prior background of the field finds it readable. The book is primarily intended for research students in sensor networks and IoT applications (including intelligent information systems, and smart sensors applications), academics in higher education institutions including universities and vocational colleges, policy makers and legislators. .
    Type of Medium: Online Resource
    Pages: X, 865 p. 314 illus., 209 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030642587
    Series Statement: Studies in Distributed Intelligence,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Natural disasters. ; Environmental geography. ; Physical geography. ; Cartography. ; Earth sciences. ; Geographical Information System. ; Natural Hazards. ; Integrated Geography. ; Physical Geography. ; Cartography. ; Earth Sciences.
    Description / Table of Contents: Chapter 1. Introduction to Spatial Modeling of Flood Risk and Hazard: Societal Implication -- Chapter 2. Flood Susceptibility Mapping Using Morphometric Techniques and GIS -- Chapter 3. Palaeohydrologic Estimates of Flood Discharge of Lower Ramganga River Catchment of Ganga Basin, India Using Slackwater Deposits -- Chapter 4. Flood Risk Zone Identification Using Ground Based Observation and Geospatial Technology -- Chapter 5. Dynamics River Networks and Determination of the Flood Potential in Lower Brahmaputra Valley Using Geoinfromatics -- Chapter 6. Flood Vulnerability Assessment Using AHP and Frequency Ratio Techniques -- Chapter 7. Application of Hybrid Machine Learning Algorithms for Flood Susceptibility Modelling -- Chapter 8. Flash Flood Susceptibility Mapping Using GIS Based AHP Method -- Chapter 9. GIS Based Hydrological and Hydraulic Models to Forecast River Flood Risks and Proposition of Management Measures -- Chapter 10. Large Scale Human Intervention and Estimation of Flood Susceptibility Applying Frequency Ratio Model -- Chapter 11. Flood Induced Transport Infrastructural Losses in India: Regional Assessments -- Chapter 12. Rural-Urban Differential in Flood Vulnerability and Community Preparedness for Flood Management Strategies -- Chapter 13. Application of Geospatial Techniques for Urban Flood Management: A Review.
    Abstract: Floods and flash floods with hydro-meteorological and tropical cyclones are the some of the most devastating natural disasters causing massive damages to natural and man-made features. Flood hazards are a major threat to human life, properties (agricultural area, yield production, building and homes) and infrastructures (bridges, roads, railways, urban infrastructures, etc). Flood hazards susceptibility mapping (risk assessment) and modelling is an essential step for early warning systems, emergency services, prevention and mitigation of future environmental and social hazards and implementation of risk management strategies. Due to the lack of proper information, technology-based policies and strategies, mapping and modelling can often not be implemented to the best possible level. Geo-spatial techniques have enjoyed rising interest in recent decades among the earth environmental and social sciences research communities for their powerful ability to solve and understand various complex problems and develop novel approaches toward sustainable earth and human society. By linking geo-spatial computational intelligence techniques with societal and environmental-oriented problems, this book demonstrates geospatial technology approaches to data mining techniques, data analysis, modelling, risk assessment and visualization and management strategies in different aspects of flood hazards. We believe that a diverse group of academics, scientists, geographers, hydrologist, remote sensing and GIS expertise, environmentalists, meteorologists and computing experts with a common interest in geospatial sciences within the earth environmental sciences and humanistic and social sciences will find this book to be of great value.
    Type of Medium: Online Resource
    Pages: XIX, 238 p. 120 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030945442
    Series Statement: GIScience and Geo-environmental Modelling,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Big data. ; Data mining. ; Architecture. ; Design. ; Urban ecology (Biology). ; Geographical Information System. ; Big Data. ; Data Mining and Knowledge Discovery. ; Architecture. ; Design. ; Urban Ecology.
    Description / Table of Contents: The introduction to informed urban environments -- The bigger picture en route to informed urban environments -- How we see now: Traversing a data-mosaic -- The role of information modelling and computational ontologies to support the design, planning and management of urban environments: Current status and future challenges -- Urban adaptation – Insights from information physics and complex system dynamics -- Decoding cool urban forms: Using open data to build a dialogue between microclimate and configurational morphology in urban environments -- From Amsterdam to New Amsterdam to Amsterdam: How urban mobility shapes cities -- urban microclimate spatiotemporal mapping: A method to evaluate thermal comfort availability in urban ecosystems -- Urban ecosystems and nature-based solutions: The role of data in optimizing the provision of ecosystem services -- Smart urban forestry: Is it the future?- Big data and decision support in rural and urban agriculture.
    Abstract: This book collects ground-breaking works on the actual and potential impact of big data and data-integrated design for resilient urban environments, including human- and ecology-centred perspectives. Comprehending and designing for urban social, demographic and environmental change is a complex task. Big data, data structuring, data analysis (i.e. AI and ML) and data-integrated design can play a significant role in advancing approaches to this task. The themes presented in this book include urban adaptation, urban morphology, urban mobility, urban ecosystems, urban climate, urban ecology and agriculture. Given the compound nature of complex sustainability problems, most chapters address the correlation between several of these themes. The book addresses practitioners, researchers and graduate students concerned with the rapidly increasing role of data in developing urban environments.
    Type of Medium: Online Resource
    Pages: XI, 195 p. 39 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031038037
    Series Statement: The Urban Book Series,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Medical sciences. ; Geography. ; Quantitative research. ; Geographical Information System. ; Health Sciences. ; Regional Geography. ; Data Analysis and Big Data.
    Description / Table of Contents: Chapter 1. How covid changed our daily geographies -- Chapter 2. Geography of the pandemic -- Chapter 3. Defining first- and second-order impacts through maps -- Chapter 4. Quantitative geographical approaches in COVID-19 research: A review on first- and second-order impacts -- Chapter 5. COVID-19’s impact on geospatial data: ethics and values -- Chapter 6. The City and the Pandemic - the Cities’ COVID Mitigation Mapping (C2M2) Program -- Chapter 7. Improving access to health services in Mongolia via open data during and beyond the COVID-19 pandemic -- Chapter 8. The inequities in the U.S. during the COVID-19 pandemic -- Chapter 9. The Latine community and COVID-19: nuances, experiences, and data -- Chapter 10. An overview of the impact of COVID-19 in Nepal’s international tourism industry -- Chapter 11. Data and dashboards for measuring the social impact of COVID-19 in African cities -- Chapter 12. COVID-19 and domestic violence complaints in Quito, Ecuador: temporal and spatial patterns and drivers -- Chapter 13. Mapping COVID-19: Should it be based on the incidence rate? A case study in China -- Chapter 14. Regional patterns of the pandemic: a view from Aotearoa New Zealand -- Chapter 15. Aboriginal and Torres Strait Islander peoples & the COVID-19 pandemic: a spatial and place-based analysis -- Chapter 16. Impacts of COVID-19 pandemic lockdown on the livelihoods of male commercial Boda-Boda motorists in Uganda -- Chapter 17. Geospatial techniques for mapping the spatial trajectories of COVID-19 -- Chapter 18. Digital geographies and digital surveillance technologies: power and space in the Italian society under control for public health -- Chapter 19. Resilience amid uncertainty: COVID-19 pandemic, the urban informal sector, and livelihoods in sub-Saharan Africa -- Chapter 20. Freshwater Resources and COVID-19 -- Chapter 21. Preventing pandemics: earth observations for One Health -- Chapter 22. Enabling Accelerated Research in Times of Need: The National Science Foundation’s Response to COVID-19 in 2020 -- Chapter 23. Conclusion - The consequences of COVID-19 – What’s next?.
    Abstract: This volume of case studies focuses on the geographies of COVID-19 around the world. These geographies are located in both time and space concentrating on both first- and second-order impacts of the COVID-19 pandemic. First-order impacts are those associated with the immediate response to the pandemic that include tracking number of deaths and cases, testing, access to hospitals, impacts on essential workers, searching for the origins of the virus and preventive treatments such as vaccines and contact tracing. Second-order impacts are the result of actions, practices, and policies in response to the spread of the virus, with longer-term effects on food security, access to health services, loss of livelihoods, evictions, and migration. Further, the COVID-19 pandemic will be prolonged due to the onset of variants as well as setting the stage for similar future events. This volume provides a synopsis of how geography and geospatial approaches are used to understand this event and the emerging “new normal.” The volume's approach is necessarily selective due to the global reach of the pandemic and the broad sweep of second-order impacts where important issues may be left out. However, the book is envisioned as the prelude to an extended conversation about adaptation to complex circumstances using geospatial tools. Using case studies and examples of geospatial analyses, this volume adopts a geographic lens to highlight the differences and commonalities across space and time where fundamental inequities are exposed, the governmental response is varied, and outcomes remain uncertain. This moment of global collective experience starkly reveals how inequality is ubiquitous and vulnerable populations – those unable to access basic needs – are increasing. This place-based approach identifies how geospatial analyses and resulting maps depict the pandemic as it ebbs and flows across the globe. Data-driven decision making is needed as we navigate the pandemic and determine ways to address future such events to enable local and regional governments in prioritizing limited resources to mitigate the long-term consequences of COVID-19.
    Type of Medium: Online Resource
    Pages: XXXI, 300 p. 57 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031117756
    Series Statement: Global Perspectives on Health Geography,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Physical geography. ; Control engineering. ; Robotics. ; Automation. ; Human ecology Study and teaching. ; Human geography. ; Geographical Information System. ; Physical Geography. ; Control, Robotics, Automation. ; Environmental Studies. ; Human Geography.
    Description / Table of Contents: Section 1 – sUAS Basics -- Introduction and outline for book – Konsoer, Leitner, Lewis -- Provide brief history of sUAS and the rapid technological advancements in recent years that have led to drone revolution and close range remote sensing -- Outline of book and intended uses as both a collection of specific research topics in geography and as a teaching tool -- Rules and Regulations for sUAS use in the United States (and/or globally, selected countries?) -- FAA regulations -- Essentials of proper and safe sUAS use -- sUAS Ethics and other considerations (privacy issues) -- Communicating Science with sUAS -- Section 2 – Applications in Human Geography -- Crime Geography (e.g., security, surveillance/monitoring, etc.) -- Sociocultural Geography (e.g., monitoring cultural resources) -- 3D Mapping -- Section 3 – Applications in Physical Geography -- Geomorphology -- Climatology -- Biogeography (e.g., precision agriculture, habitat monitoring, etc.) -- Section 4 – Applications in Interdisciplinary Research -- Environmental Geography (e.g., water quality, algae, land use changes) -- Mississippi River Delta Archaeological Mitigation (MRDAM) (e.g., geomorphology and archaeology – Konsoer et al) -- Disaster Science Management (e.g. search and rescue operations, damage assessment).
    Abstract: The use of small unoccupied aerial systems (sUAS) for acquiring close-range remotely sensed data has substantially increased in the past 5 years. A primary focus of early research was on physical systems and photogrammetric techniques. However, as sUAS technology continues to improve and more sophisticated payloads are utilized, such as lidar and multispectral cameras, applications have expanded to nearly all subdisciplines within Geography. This edited volume is intended to showcase the various ways in which sUAS are used in geographic research, including geomorphology, environmental and hazard monitoring, biogeography, and urban and sociocultural geography.
    Type of Medium: Online Resource
    Pages: VI, 331 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031019760
    Series Statement: Geotechnologies and the Environment, 24
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Cartography. ; Geography. ; Geographical Information System. ; Cartography. ; Geography. ; Regional Geography.
    Description / Table of Contents: Assessment on the Distribution and Accessibility to Green Spaces in Mexico’s Most Populated Metropolitan Zones -- Geomatics Assessment of Water Resources in a Transboundary Basin -- Geospatial Analysis of Clandestine Graves in Baja California: New Approaches for the Search of Missing Persons in Mexico -- The Geopolitical Repercussions of the Migration Rhetoric of Donald Trump on Mexican Anti-immigrant Speech Online: A Transdisciplinary Approach -- Spatial Analysis of a Forest Socio-Ecological System in Oaxaca, Mexico Based on the DPSIR Framework -- Fourier Transform Based Methods for Unwrapping of Sentinel-1 Interferograms -- Methodology and Relevant Results About an Area-Based Conservation Indicator of Superficial Water Bodies for the Grijalva Basin -- Social Vulnerability Analysis of Three High Mountain Villages at Pico de Orizaba Volcano, Mexico, Using PCA -- Detection of Phoradendron velutinum Implementing Genetic Programming in Multispectral Aerial Images in Mexico City -- Assessment of the Reduction of the Icesnow Coverage at the TransMexican Volcanic Belt Through Empirical Mode Decomposition on Satellite Imagery -- Forest Degradation Estimation Through Trend Analysis of Annual Time Series NDVI, NDM and NDFI (2010-2020) using Landsat images -- Estimating Importation Risk of COVID-19 in Hurricane Evacuations: A Prediction Framework Applied to Hurricane Laura in Texas -- A Dynamic Social Vulnerability Index to COVID-19 in Mexico -- Effects of COVID-19 in Mexico City: Street Robbery and Vehicle Theft Spatio-Temporal Patterns.
    Abstract: This book presents a selection of manuscripts submitted to the 2nd International Conference on Geospatial Information Sciences 2021, a virtual conference held on November 3-5, 2021. These papers were selected by the Scientific Program Committee of the Conference after a rigorous peer-review process. They represent the vast scope of the interdisciplinary research areas that characterize the Geospatial Information Sciences that is done in the discipline. It especially represents a fabulous opportunity to showcase research carried out by young Mexican researchers and showcase it to the rest of the world and enhance the growth of the sciences in the country while, at the same time, enforces them to level up with other research at the international level.
    Type of Medium: Online Resource
    Pages: XIV, 205 p. 67 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030980962
    Series Statement: Lecture Notes in Geoinformation and Cartography,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Physical geography. ; Earth sciences. ; Signal processing. ; Computer vision. ; Geographical Information System. ; Fossil Fuel. ; Physical Geography. ; Earth Sciences. ; Digital and Analog Signal Processing. ; Computer Vision.
    Description / Table of Contents: Chapter 1-Electromagnetic spectral bands used for RS in HC exploration -- Chapter 2-Foundations of multi-spectral image processing -- Chapter 3-Surface elevation and surface texture from microwave radar -- Chapter 4-Surface cover from optical and thermal IR -- Chapter 5-Geomorphology and Mapping -- Chapter 6-Near-surface characteristics from optical, thermal IR and microwave radar -- Chapter 7-Basement depth and texture from radar distance anomalies -- Chapter 8-Mapping of temporal changes -- Chapter 9-Frontier exploration -- Chapter 10-Seismic planning, acquisition and data processing -- Chapter 11-Development and oilfield infrastructure planning -- Chapter 12-Geological analogs. .
    Abstract: This book provides insights into the benefits of using remote sensing data from a geoscientist's perspective, by integrating the data with the understanding of Earth's surface and subsurface. In 3 sections, the book takes a detailed look at what data explorationists use when they explore for hydrocarbon resources, assess different terrain types for planning and hazards and extract present-day geologic analogs for subsurface geologic settings. The book presents the usage of remote sensing data in exploration in a structured way by detecting individual geologic features as building blocks for complex geologic systems. This concept enables readers to build their own workflows for the assessment of complex geologic systems using various combinations of remote sensing data. Section 1 introduces readers to the foundations of remote sensing for exploration, covers various methods of image processing and studies different digital elevation and bathymetry models. Section 2 presents the concept of geomorphology as a means to integrate surface and subsurface data. Different aspects of rendering in 2D and 3D are explained and used for the interpretation and extraction of geologic features that are used in exploration. Section 3 addresses remote sensing for hydrocarbon exploration in detail, from geophysical data acquisition to development and infrastructure planning. The organization of this chapter follows an exploration workflow from regional to local modeling studying basin and petroleum system modeling as well as logistics planning of seismic surveys and near-surface modeling. Aspects of field development and infrastructure planning comprise multi-temporal and dynamic modeling. The section closes with a structured approach to extracting geologic analogs from interpreted remote sensing data. The book will be of interest to professionals and students working in exploration for hydrocarbons and water resources, as well as geoscientists and engineers using remote sensing for infrastructure planning, hazard assessment and dynamic environmental studies.
    Type of Medium: Online Resource
    Pages: LVII, 348 p. 8 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030733193
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Aerospace engineering. ; Astronautics. ; Environmental monitoring. ; Control engineering. ; Robotics. ; Automation. ; Geographical Information System. ; Aerospace Technology and Astronautics. ; Environmental Monitoring. ; Control, Robotics, Automation.
    Description / Table of Contents: Chapter 1. Unmanned Aircraft Systems and the Nordic Challenges -- Chapter 2. Applying an icing wind tunnel for drone propeller research, validation of new measurement instrument -- Chapter 3. Self-Swarming for Multi-Robot Systems Deployed for Situational Awareness -- Chapter 4. Toward Invisible Drones – An Ultra-HDR Optical Cloaking System -- Chapter 5. Long-Term Autonomy in Forest Environment using Self-Corrective SLAM -- Chapter 6. Future Possibilities and Challenges for UAV-based Imaging Development in Smart Farming -- Chapter 7. Role of Drones in Characterizing Soil Water Content in Open Field Cultivation -- Chapter 8. Ground penetrating radar mounted drones in agriculture -- Chapter 9. A minimalist approach to yield mapping of standing wheat crop with unmanned aerial vehicles -- Chapter 10. Assessment of Crop Yield Prediction Capabilities of CNN using Multisource Data.
    Abstract: This volume presents the conference proceedings from FinDrones2020. The book highlights recent developments in drone technology by experts, academicians, and entrepreneurs for applications in agriculture, forestry, and other industries. Emphasis is placed on contextualizing the conference presentations and content to Finland and the unique challenges typical to this region. The work will be of interest to academicians and professionals involved in remote sensing applications of unmanned aerial vehicles, as well as enthusiasts of drone technological developments.
    Type of Medium: Online Resource
    Pages: X, 195 p. 56 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030778606
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Natural disasters. ; Landscape ecology. ; Physical geography. ; Geographical Information System. ; Natural Hazards. ; Landscape Ecology. ; Physical Geography.
    Description / Table of Contents: Introduction -- Preface -- Section-I : Land Use Land Cover Dynamics -- Section-II: Agriculture water Management.-Section III: Water Resources Assessment and Modelling -- Section IV: Natural Disasters -- Conclusions and Recommendations.
    Abstract: This book focuses on the application of geospatial technologies to study the land use land cover (LULC) dynamics, agricultural water management, water resources assessment and modeling, and studies on natural disasters. LULC dynamics is one of the major research themes for studying global environmental change using remote sensing data. The section on LULC dynamics covers the multi-variate criteria for land use and land cover classification and change assessment in the mountainous regions. Further, LULC change detection of the Tons river basin and LULC dynamics at decadal frequency are studied to derive adaptation and mitigation strategies. Landscape-level forest disturbance modeling, together with conservation implications, is also included. The watershed management approach is necessary for comprehensive management of land and water resources of any region, where studies on multi-criteria analysis for rainwater harvesting planning and its impact on land use land cover transformations in rain-fed areas using geospatial technologies are presented in this book. The book will be useful for academics, water practitioners, scientists, water managers, environmentalists, and administrators, NGOs, researchers, and students who are actively involved in the application of geospatial technologies in LULC studies, agricultural water management and hydrological modelling and natural disasters for addressing the challenges being posed by climate change while addressing issues of food and water securities .
    Type of Medium: Online Resource
    Pages: VIII, 621 p. 251 illus., 213 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030904791
    Series Statement: Water Science and Technology Library, 103
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Agriculture. ; Environment. ; Landscape ecology. ; Human ecology Study and teaching. ; Geographical Information System. ; Agriculture. ; Environmental Sciences. ; Landscape Ecology. ; Environmental Studies.
    Description / Table of Contents: Chapter 1. Agricultural Information Needs and Research Priorities for Remote Sensing in South and Southeast Asian Countries (Krishna Vadrevu, Thuy Le Toan, Shibendu Ray and Chris Justice) -- Part I: International, Regional and National Programs in Agriculture -- Chapter 2. South/Southeast Asia Research Initiative and Agricultural Research Projects (Krishna Vadrevu) -- Chapter 3. The NASA Harvest program on Agriculture and Food Security (Inbal Becker-Reshef, Varaprasad Bandaru, Brian Barker,Sylvain Coutu, Jillian M Deines, Bradley Doorn, Gary Eilerts, Belen Franch, Antonio Sanchez Galvez, Mehdi Hosseini1, Michael Humber, Greg Husak, Kaiyu Guan, Christina Justice, John Keniston, Hannah Kerner, Mary Mitkish, Kara Mobley, Blake Munshell, Catherine Nakalembe, Estefania Puricelli, Ritvik Sahajpal, Sergii Skakun, Eric Vermote, Alyssa Whitcraft, Matthew Hansen, Bill Salas, and Christopher Justice) -- Chapter 4. Asia-RiCE: Collaborative framework for Rice Crop Management in Asia (Shinichi Sobue, and Lal Samarakoon, Matthew Steventon, Kei Oyoshi, Thuy Le Toan) -- Chapter 5. Rice Growth Outlook using Satellite-Based Information in Southeast Asia (Kei Oyoshi, Shinichi Sobue, and Shoji Kimura) -- Chapter 6. RIICE – The service and its operational use (Francesco Holecz, Tri Setiyono, Massimo Barbieri, Francesco Collivignarelli, Luca Gatti, Michael Anthony, Renaud Mathieu, Emma Quicho, Aileen Maunahan, Sushree Satapathy, Deiveegan Murugesan, Ponnurangam Ganesan, Alice Laborte, Mary Rose Mabalay, Jovino de Dios, Eduardo Jimmy Quilang, Men Sothy, Pich Rothana, Vang Seng, Ngin Chhay, Chharom Chin, Phuong Do Minh, Hung Bui Vang, Vo Quoc Tuan, Tuong Chi Quang, Vo Quang Minh, Ninh Nguyen Hong, Sellaperumal Pazhanivela, Bernard Zaugg) -- Chapter 7. The Philippine Rice Information System (PRiSM): An operational monitoring and information system on rice (Mary Rose Mabalay, Jeny Raviz, Elmer Alosnos, Massimo Barbieri, Emma Quicho, Jesiree Elena Ann Bibar, Mabel Barroga, Meriam Coñado, Pristine Mabalot, Jean Rochielle Mirandilla, Arturo Arocena, Juanito Maloom, Gerald Bello, Ederlina Cariño, Gina de Mesa, Norlyn Detoito, Harvey Gonzaga, Nonilon Martin, Mitzi Philline Tejada, Mary Jane Vives, Marjie Lastimoso, Darlynne Kaye Bumagat, Henry Cayaban, Michael Barroga, Ruvicyn Bayot, Abel Melquiades Callejo, Neale Marvin Paguirigan, Mary Anne Gutierrez, Gene Christhopher Romuga, Frances Grace Amanquiton, Janica Gan, Ethel Princess Banasihan, Creigton Czar Guevarra, Arnel Rala, Hilario Yonson, Michael Malonzo, Glorie Belle Berja, Consolacion Diaz, Luis Alejandre Tamani, Ronald Gregory Roces, Sonia Asilo, Jovino de Dios, Tri Deri Setiyono, Francesco Holecz, Eduardo Jimmy Quilang, and Alice Laborte) -- Chapter 8. An Initiation of National Institute for Precision Agriculture Research Network: A case of Thailand Research Fund and Thailand Science Research and Innovation (Attachai Jintrawet, Prapaporn Khopaibool, Thongchai Suwansichon) -- Part II: Crop Mapping, Monitoring, Yield and Water Resources -- Chapter 9. Varietal Discrimination, Acreage Estimation and Yield Prediction of Basmati Aromatic Rice in North-Western India Using Satellite Data (Dharmesh Verma, A. N. Singh, Manik H. Kalubarme, G.P. Saroha, Ritesh Sharma and Brajendra) -- Chapter 10. Mapping Smallholder Yields Using Planet and Sentinel-2 Satellite Data (Meha Jain, Weiqi Zhou, Ambica Paliwal) -- Chapter 11. A Data-analytical way of estimating Rice crop Yield: Economic and Water related causative factors (Nilabja Ghosh, M. Rajeshwor, Alka Singh, Satarupa Chakravarty) -- Chapter 12. Rice Monitoring in Southeast Asia Using Earth Observation Satellite Data (Kei Oyoshi, Lal Samarakoon, Shin-chi Sobue, Sotheavy Meas, Men Sothy, Shoji Kimura, Rizatus Shofiyati, Tanita Suepa, Kanjana Koedkurang, Yootthapoom Potiracha6,, Sutinee Sihirunwong, Patiwet Chalearmpong, Panu Nuangjumnong, Damrongrit Niammuad, and Soravis Supavetch, Phung Hoang-Phi,Nguyen Lam-Dao,and Thuy Le Toan) -- Chapter 13. Crop LAI and biomass estimation from different polarization modes of simulated NISAR data (Dipankar Mandal, Vineet Kumar, Avik Bhattacharya and Y. S. Rao) -- Chapter 14. Pixel-based evaluation of rice production and related greenhouse gas emissions in the Mekong Delta integrating SAR data and ground observations (Hironori Arai, Wataru Takeuchi, Kei Oyoshi, Lam Dao Nguyen, Tamon Fumoto, Kazuyuki Inubushi and Thuy Le Toan) -- Chapter 15. The utilization of satellite data to support wet season rice production policy in Thailand: A review of practices and opportunities (Chitnucha Buddhaboon, Panu Neungchumnong, Thewin Kaeomuangmoon and Attachai Jintrawet) -- Chapter 16. Productivity, damages, and losses of rice in Cambodia: past, present and future trends in the Mekong and Tonle Sap regions (Serey Sok, Hoeurn Cheb, Nyda Chhinh and Pheakdey Nguonphan) -- Chapter 17. Rice growth stage monitoring and yield estimation in the Vietnamese Mekong Delta using multi-temporal Sentinel-1 data (Phung Hoang-Phi, Nguyen Lam-Dao, Vu Nguyen-Van-Anh, Thanh Nguyen-Kim, Thuy Le Toan, and Tien Pham-Duy) -- Chapter 18. Agricultural Drought Assessment using Remote Sensing, with special emphasis on India (S. S. Ray, Shalini Saxena, K. Choudhary, Preeti Tahlani and Krishna Vadrevu) -- Chapter 19. Role of remote sensing in assessing total water storage and evapotranspiration for croplands in the Mekong river basin (Venkataramana Sridhar, Syed Azhar Ali) -- Part III: Prediction and Modeling -- Chapter 20. Random forests for early rice yield prediction from time series of remote sensed data (Nguyen-Thanh Son, Chi-Farn Chen, Cheng-Cru Chen) -- Chapter 21. Assessment of Climate Change Impact on Rice production over South and Southeast Asia under CMIP6 climate scenarios (Tzu-Shun Lin and Atul K Jain) -- Chapter 22. Application of Geo-CropSim framework for Rainfed Sugarcane Yield Assessment in Thailand (Varaprasad Bandaru, Pallavi Cherumalli, Sergii Skakun, Kristofer Lasko, Sukunya Yampracha) -- Chapter 23. Crop yield assessment of smallholder farms using remote sensing and simulation modeling (Vinay Kumar Sehgal, Debasish Chakraborty, Rajkumar Dhakar, Joydeep Mukherjee, Rabi Narayan Sahoo) -- Part IV: Agricultural Land Cover/Land Use Changes -- Chapter 24. Agricultural intensity assessment in Punjab India using food security metrics and remote sensing data (Krishna Vadrevu, Emily Casadaban, Aditya Eaturu, Samuel Amborski and Sumalika Biswas) -- Chapter 25. Agricultural intensity assessment in Punjab India using food security metrics and remote sensing data (Bhavani P, Ripan Das, Mariam Jamilah, Vijay P.Kanawade, Chandrashekhar Biradar and P.S. Roy) -- Chapter 26. Nexus of Urbanization and Changes in Agricultural Land in Bangladesh (Mst. Ilme Faridatul, Md. Sarfaraz Gani Adnan and Ashraf Dewan) -- Chapter 27. The Kandyan Home Garden – Sustainable Agricultural Ecosystem in Sri Lanka (A.R. Gunawardena and T.T. Fernando) -- Chapter 28. Agricultural transformation, and deforestation in Shan State, Myanmar (Sumalika Biswas and Krishna Prasad Vadrevu) -- Chapter 29. Agricultural fires in South Asian Countries and Implications (Krishna Vadrevu, Emily Casadaban, Aditya Eaturu and Sumalika Biswas) -- Chapter 30. Agricultural Land-Use Trends in Vietnam 1990 – 2020 (Stephen J. Leisz, Nghiem Thi Tuyen, Ngo The An, Nong Duong, Nguyen Thi Bich Yen) -- Chapter 31. Scenario-Based Land-Cover/Land-Use Change Modeling of Future Agricultural Land Conversion in Dong Thap, Vietnam (Keelin Haynes, Jessica L. McCarty, Stanley W. Toops, Bui Thi Minh Ha, Jarrod W. Brown, Peter Potapov, Svetlana Turubanova, Quyen Nguyen, Peou Touch, and Justin J. Fain) -- Chapter 32. Extreme Development of Dragon Fruit Agriculture with Nighttime Lighting in Southern Vietnam (Shenyue Jia, Son V. Nghiem, Seung-Hee Kim, Laura Krauser, Andrea E. Gaughan, Forest R. Stevens, Menas Kafatos, and Khanh D. Ngo) -- Chapter 33. Agricultural Land Use/Cover Changes in the Vientiane, Laos (Chittana Phompila, Vongphet Sihapanya, Bakham Chanthavong, Sithong Thongmanivong, Phung Van Khoa, Keigo Noda and Krishna Prasad Vadrevu) -- Chapter 34. Color Features Based Model for Land Cover Identification and Agriculture Monitoring with Satellite Images (Shruti Gupta and Dharmendra Singh) -- Index.
    Abstract: This book sheds new light on the remote sensing of agriculture in South/Southeast Asian (S/SEA) countries. S/SEA countries are growing rapidly in terms of population, industrialization, and urbanization. One of the critical challenges in the region is food security. In S/SEA, although total food production and productivity have increased in previous decades, in recent years, the growth rate of food production has slowed down, mostly due to land use change, market forces and policy interventions. Further, the weather and climate systems in the region driven primarily by monsoon variability are resulting in droughts or flooding, impacting agricultural production. Therefore, monitoring crops, including agricultural land cover changes at regular intervals, is essential to predict and prepare for disruptions in the food supply in the S/SEA countries. The current book captures the latest research on the remote sensing of agricultural land cover/ land use changes, including mapping and monitoring crops, crop yields, biophysical parameter retrievals, multi-source data fusion for agricultural applications, and chapters on decision making and early warning systems for food security. The authors of this book are international experts in the field, and their contributions highlight the use of remote sensing and geospatial technologies for agricultural research and applications in South/Southeast Asia.
    Type of Medium: Online Resource
    Pages: XXVII, 617 p. 234 illus., 217 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030923655
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Database management. ; Education. ; Regional economics. ; Spatial economics. ; Application software. ; Geographical Information System. ; Database Management. ; Education. ; Regional and Spatial Economics. ; Computer and Information Systems Applications.
    Description / Table of Contents: Chapter 1. Three Scales of the Spatial University -- Chapter 2. U-Spatial: Nexus of the Spatial University -- Chapter 3. Spatial university for service and support -- Chapter 4. Spatial thinking and learning -- Chapter 5. Spatial science and research -- Chapter 6. Future of the Spatial University.
    Abstract: This volume discusses the concept of The Spatial University as part of the broad growth of spatial science and the need for spatial infrastructure in colleges and universities. The book centers on the development of U-Spatial, the spatial science infrastructure at the University of Minnesota that offers a range of spatial activities and services, including data access, training, and community building. Against a backdrop of the changing nature of research, teaching, and service in higher education, the story of U-Spatial anchors a broader discussion of what it means to be a spatial university. This narrative framing demonstrates—with specific examples—the importance of institutions offering dedicated spatial research infrastructure. In six chapters, the text explores the importance of spatial thinking, learning, and research for student and researcher success. The volume offers lessons that are applicable far beyond the University of Minnesota to apply to a broad array of domains and institutional specializations. The book will be useful to students, researchers, and policymakers concerned with how institutions can encourage spatial research, teaching, and service. It will also appeal to researchers and practitioners interested in broader uses of spatial science. This book shows how GIS can transform a university, speaking to the need for leadership in higher education around the power of bringing everything together using spatial and geographic concepts. Jack Dangermond Co-Founder and President, Esri.
    Type of Medium: Online Resource
    Pages: XIII, 118 p. 18 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030928476
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Natural disasters. ; Geology. ; Computational intelligence. ; Geographical Information System. ; Natural Hazards. ; Geology. ; Computational Intelligence.
    Description / Table of Contents: Chapter 1 -- Introduction to Part I: Geo-physical Hazards -- Chapter 2-Determination of the Probabilities of Landslide Events -A Case Study -- Chapter 3-Geoinformatics based analysis of landslide stability - A Case Study -- Chapter 4-Land Degradation and Desertification- A Case Study. Chapter 5 -- River bank erosion mapping using GIS techniques -- Chapter 6-Geo-spatial modeling of Potential soil erosion estimation for better conservation planning -- Chapter 7-Vulnerability and Risk Assessment of the Bengal Coast, India- a GIS approach -- Chapter 8-Seismic hazard, and vulnerability of assessment for the earthquake scenario-A case study -- Chapter 9-Geo-spatial techniques for mapping, monitoring and modeling shoreline to support coastal risk management -- Chapter 10-Introduction to Part II: Hydro-meteorological Hazards -- Chapter 11-Flood susceptibility analysis based on GIS frequency ratio model -- Chapter 12-Meteorological and agriculture drought monitoring –GIS based approach -- Chapter 13-Geospatial technology and agricultural water resources management -- Chapter 14-Land-Use Suitability Modeling for Agricultural Sustainability -- Chapter 15-Recent trends in climate adaptive water resources management -- Chapter 16-GIS based Spatial analysis on flood modeling - A case study -- Chapter 17-Investigating Vulnerability of Ground Water using AHP and GIS Techniques: A Study -- Chapter 18-Flood Risk zone identification using RS & GIS Techniques -- Chapter 19-Groundwater quality delineation based on Fuzzy Comprehensive Assessment Method -- Chapter 20-Introduction to Part III: Bio-physical Hazards -- Chapter 21-Forest Fire Geo knowledge based Modeling using GIS -- Chapter 22-GI based modelling for wildland fire risk assessment -- Chapter 23-Distribution of Urban Crime Analysis Using GPS, and GIS techniques -- Chapter 24-Analysis of Poverty allocation using Geoinformatics -- Chapter 25-Risk and hazards mapping of Social-economic vulnerability Using GIS techniques.
    Abstract: The book demonstrates the geospatial technology approach to data mining techniques, data analysis, modeling, risk assessment, visualization, and management strategies in different aspects of natural and social hazards. This book has 25 chapters associated with risk assessment, mapping and management strategies of environmental hazards. It covers major topics such as Landslide Susceptibility, Arsenic Contaminated Groundwater, Earthquake Risk Management, Open Cast Mining, Soil loss, Flood Susceptibility, Forest Fire Risk, Malaria prevalence, Flood inundation, Socio-Economic Vulnerability, River Bank Erosion, and Socio-Economic Vulnerability. The content of this book will be of interest to researchers, professionals, and policymakers, whose work involves environmental hazards and related solutions.
    Type of Medium: Online Resource
    Pages: XIX, 588 p. 201 illus., 173 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030751975
    Series Statement: Advances in Geographic Information Science,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Radiology. ; Spectrum analysis. ; Pharmaceutical chemistry. ; Nutrition   . ; Biomedical Research. ; Radiology. ; Spectroscopy. ; Pharmaceutics. ; Nutrition.
    Description / Table of Contents: Ch 1: Electron Spin Resonance- An Introdcution -- Ch 2: ESR – Applications in Healthcare and Pharmaceutical Science -- Ch 3: ESR Applications in Paleontology and Geochronology -- Ch 4: ESR Applications in Food Science.
    Abstract: This book introduces the audience with basic theoretical and experimental aspects of Electron Spin Resonance (ESR) Spectroscopy. It further talks about ESR spectroscopy applications in Healthcare & Pharmaceutical Science, Paleontology & Geochronology and Food Science. Mathematical details have been kept to a necessary minimum and emphasis is given to highlight the applications of the technique.
    Type of Medium: Online Resource
    Pages: X, 72 p. 32 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030641986
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    DDC: 610.72
    Language: English
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  • 76
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    DDC: 610.72
    Language: English
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  • 77
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Reproductive health. ; Cytology. ; Biomedical Research. ; Reproductive Medicine. ; Cell Biology.
    Description / Table of Contents: Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases -- Ch 2: Sertoli cells: immunology and spermatogenesis -- Ch 3: Innate immunity and spermatogenesis -- Ch 4: Cell apoptosis and spermatogenesis -- Ch 5: Transcriptional regulation of spermatogenesis -- Ch 6: Sertoli cell cytoskeleton and spermatogenesis -- Ch 7: Leydig cell and spermatogenesis -- Ch 8: Cross-talk of cell junctions to support spermatogenesis -- Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis -- Ch 10: Regulation of the blood-testis barrier by basement membrane laminin-α2 chain -- Ch 11: Regulation of spermatogenesis by collagens -- Ch 12: Androgen regulation of spermatogenesis -- Ch 13: Use of molecular modeling to study spermatogenesis -- Ch 14: Acrosome biogenesis during spermatogenesis -- Ch 15: Stem cells and spermatogenesis -- Ch 16: Advances in our understanding of spermatogenesis in humans -- Ch 17: Leydig cell function in aging men -- Ch 18: Regulation of human spermatogenesis.
    Abstract: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
    Type of Medium: Online Resource
    Pages: X, 319 p. 44 illus., 40 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030777791
    Series Statement: Advances in Experimental Medicine and Biology, 1381
    DDC: 610.72
    Language: English
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  • 78
    Keywords: Medicine Research. ; Biology Research. ; Nutrition   . ; Food science. ; Chemistry, Organic. ; Biomedical Research. ; Nutrition. ; Food Science. ; Organic Chemistry.
    Description / Table of Contents: Part I: An overview of cancer and its mechanisms -- 1-A brief overview of cancer, its mechanisms, and prevention methods -- 2-MECHANISMS INVOLVED IN CARCINOGENESIS -- Part II: Functional foods/nutraceuticals as chemo preventive agents -- 3-Tomato (lycopene and β-carotene) and cancer -- 4-Essential Oils from Aromatic Plants in cancer prevention and treatment -- 5-Bee propolis (caffeic acid phenethyl ester) against cancer -- 6-Brown Algae (Fucoxanthin) Against Cancer -- 7-Cruciferous vegetables (indole-3-carbinol, isothiocyanates) against cancer -- 8-Crustacea (carotenoids namely astaxanthins) against cancer -- 9-Curcuma and breast cancer: a focus on cell signaling pathways -- 10-FRUITS AND VEGETABLES IN CANCER -- 11-Garlic: Allyl Sulfur Compounds and Cancer Prevention -- 12-Ginger (gingerols and 6-shogaol) against cancer -- 13-Saffron (crocins) against cancer -- 14-OLIVE LEAF (OLEUROPEIN) AND ITS ROLE IN CANCER: THERAPEUTIC UPDATES -- 15-Honey against cancer -- 16-Soybeans and phytoestrogen rich foods (genistein, daidzein) against cancer -- 17-Tea (catechins including (-)-epigallocatechin-3-gallate) and cancer -- 18-Probiotics and Cancer -- Part III: The role of nutrients in the prevention of cancer -- 19-Vitamins (C, D and E) against cancer -- 20-Minerals (namely selenium) and cancer -- 21-Dietary fibers/beta-glucan and cancer -- 22-Omega-3 Polyunsaturated Fatty Acids and Cancer.
    Abstract: Today's consumers are looking for food products with health-promoting roles in addition to nutritional benefits. With current research showing that nutraceuticals and functional foods rich in specific bioactives may have chemopreventative effects, these products are increasingly popular. However, while much in the literature supports the health-promoting features of these foods, few texts focus on their bioactive agents and their mode of action in cancer signaling. Nutraceuticals and Cancer Signalling: Clinical Aspects and Mode of Action explains the link between nutraceuticals and cancer in terms of clinical trials and modes of action. This book gives an overview of common cancers and their mechanisms, and the most common functional foods and their bioactive components. Individual chapters focus on specific functional foods--including tomatoes, garlic, honey, tea, yoghurt, and many more--their prominent bioactive compounds, and their mode of action in cancer signaling and chemoprevention. Recent findings on cancer-prevention roles of different vitamins and minerals are also discussed. For food scientists, nutritionists, and pharmaceutical experts looking to understand how functional foods can play a role in fighting cancer, this text serves as a one-stop reference.
    Type of Medium: Online Resource
    Pages: IX, 652 p. 52 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030740351
    Series Statement: Food Bioactive Ingredients,
    DDC: 610.72
    Language: English
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  • 79
    Keywords: Medicine Research. ; Biology Research. ; Diseases. ; Genetics. ; Immunology. ; Biomedical Research. ; Diseases. ; Genetics and Genomics. ; Immunology.
    Description / Table of Contents: Ch 1: Overview of Microbial NGS -- Ch 2: WGS for Bacterial Identification and Susceptibility Testing -- Ch 3: WGS for Bacterial Virulence Assessment -- Ch 4: Epidemiological Typing by WGS -- Ch 5: Bioinformatics Approaches for WGS Analysis -- Ch 6: WGS for Clinical Virology -- Ch 7: WGS for Clinical Mycology -- Ch 8: WGS for Clinical Parasitology -- Ch 9: Long Read Sequencing -- Ch 10: Aspects of WGS Integration -- Ch 11: Microbiome Analysis -- Ch 12: Metagenomics of Environmental Samples -- Ch 13: Clinical Metagenomics -- Ch 14: Metagenomics for Pathogen Discovery -- Ch 15: Advanced Applications for MALDI-TOF: Typing -- Ch 16: Advanced Applications for MALDI-TOF: Infectious Diseases and Antibiotic Susceptibility Testing (AST) -- Ch 17: Omics for Food and Water Microbiology -- Ch 18: Omics for Forensic and Post-Mortem Microbiology -- Ch 19: Omics for Antimicrobial Resistance Surveillance -- Ch 20: Total Laboratory Automation.
    Abstract: Various “omics” methods have recently revolutionized molecular diagnostics. Next-generation sequencing (NGS) makes it possible to sequence a human genome in just one day. Whole genome sequencing (WGS) greatly improves the ability to investigate the outbreaks of numerous pathogens. Metagenomics helps to analyze the microbiome, which aids greatly in identifying the pathogenesis of infectious diseases. Proteomic-based methods, namely matrix-assisted laser desorption-ionization time of flight mass spectrometry (MALDI-TOF-MS), have a promising role in identifying myctobacteria and fungi, and predicting antimicrobial resistance. While there are numerous scientific publications on “omics” applications for microbiology, there are relatively few books that review this topic from a clinical diagnostics perspective. This book looks at this field from a holistic viewpoint, instead of limiting by type of “omics” technology, in order to cover the body of knowledge needed for practitioners and academics interested in clinical and public health microbiology. Additionally, it addresses the management, economical, regulatory and operational aspects of integrating these technologies into routine diagnostics.
    Type of Medium: Online Resource
    Pages: VI, 240 p. 17 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030621551
    DDC: 610.72
    Language: English
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  • 80
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biotechnology. ; Biomedical engineering. ; Biomedical Research. ; Biotechnology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Graviola Fruit Extraction by Ionic Liquid Microwave-assisted Extraction (IL-MAE) -- Role of Ionic Liquids in the Enzyme Stabilization: A Case Study with Trichoderma ressie Cellulase -- Role of Ionic Liquids in the Processing of Lignocellulosic Biomass -- Proliferation of rat amniotic stem cell (AFSC) on modified surface microcarrier -- Application of spectroscopic methods for the analysis of non-halal meats in food products: A narrative review -- Identification of Potential Biomarkers of Porcine Gelatin -- Gamma Ray Mutagenesis on Bacteria Isolated from Shrimp Farm Mud for Microbial Fuel Cell Enhancement and Degradation of Organic Waste -- Effect of temperature on antibacterial activity and fatty acid methyl esters of Carica papaya seed extract -- Solid-state Fermentation of Agro-industrial Waste Using Heterofermentative Lacti Acid Bacteria -- Synthesis of chitosan-folic acid nanoparticles as a drug delivery system for propolis compounds.
    Abstract: This contributed volume, “Multifaceted Protocols in Biotechnology, Volume 2”, consists of multidisciplinary methods and techniques commonly used in biotechnology studies. There are two sections covered in this book – Ionic Liquid Related Techniques & Evergreen Biotechnology Techniques. A brief introduction supports each protocol to allow easy learning and implementation. The first section consists of three chapters covering studies in modern biotechnology focusing on the role of ionic liquid techniques in extracting secondary metabolites, enzyme stabilization and biomass processing. The second section covers evergreen methodologies. It comprises five chapters covering topics on microcarrier technology for cell culture; Polymerase Chain Reaction for non-halal sources detection in food; ELISA for biomarker identification; gamma ray-induced mutagenesis for enhancing microbial fuel cells; and the effect of temperature on antibacterial activity of Carica papaya seed extract. This book will be useful to graduate students, researchers, academics, and industry practitioners working in the area of biotechnology.
    Type of Medium: Online Resource
    Pages: VII, 159 p. 45 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030755799
    DDC: 610.72
    Language: English
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  • 81
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biophysics. ; Senses and sensation. ; Nanoscience. ; Biotechnology. ; Biomedical Research. ; Sensory Systems. ; Nanophysics. ; Chemical Bioengineering.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Bioreceptors -- Chapter 3. Catalytic Biosensors -- Chapter 4. Affinity Biosensors -- Chapter 5. Affinity Biosensors -- Chapter 6. Label-free Biosensors -- Chapter 7. Bioreceptor Immobilization -- Chapter 8. Biochips. Chapter 9. Genome Sequencing -- Chapter 10. Genome Sequencing -- Chapter 11. Micro Electrode Arrays, Implants and Organs-on-a-Chip -- Appendix.
    Abstract: This textbook describes the basic principles and mechanism of action of biosensor systems, and introduces readers to the various types of biosensors; from affinity biosensors to catalytic, optical and label-free biosensors, the most common systems are explained in detail. Dedicated advanced sections focus on biochips and genome sequencing methods as well as organs-on-a-chip. The textbook helps readers to understand the elementary components of biosensors, and to identify and illustrate each function in the biosensor information flow, from recognition to transduction and transmission. Furthermore, readers will receive guidance in critically analyzing published studies on biosensor research, helping them to develop appropriate concepts and independently propose their own solutions. The textbook is intended for master’s students in bioengineering, biophysics, biotechnology and pharmacology that need a solid grasp of biosensor system technologies and applications, as well as students in related medical technological fields.
    Type of Medium: Online Resource
    Pages: XVIII, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030764692
    Series Statement: Learning Materials in Biosciences,
    DDC: 610.72
    Language: English
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  • 82
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Physiology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Physiology. ; Internal Medicine.
    Description / Table of Contents: Basic structure, physiology and biochemistry of connective tissues and extracellular matrix collagens -- Tendon Extracellular Matrix Assembly, Maintenance and Dysregulation Throughout Life -- Basic Components of Connective Tissues and Extracellular Matrix: Fibronectin, Fibrinogen, Laminin, Elastin, Fibrillins, Fibulins, Matrilins, Tenascins and Thrombospondins -- Proteoglycans and Diseases of Soft Tissues -- Growth Factor Roles in Soft Tissue Physiology and Pathophysiology -- Connective Tissue Disorders and Cardiovascular Complications: The Indomitable Role of Transforming Growth Factor-β Signaling -- The Pathophysiology and Pathogenesis of Marfan Syndrome -- Ehlers-Danlos syndromes, joint hypermobility and hypermobility spectrum disorders -- Ehlers–Danlos Syndrome Associated with Glycosaminoglycan Abnormalities -- Loeys-Dietz Syndrome -- Meester-Loeys syndrome -- Clinical and Molecular Delineation of Cutis Laxa Syndromes: Paradigms for Elastic Fiber Homeostasis -- Collagen VI Muscle Disorders: Mutation Types, Pathogenic Mechanisms and Approaches to Therapy -- Connective Tissue Disorders in Domestic Animals.
    Abstract: This volume represents a substantially revised and updated 2nd edition of a reference handbook on major structural components of soft connective tissues and a whole slew of heritable diseases of soft connective tissues. The number of clearly identifiable and distinct disorders has grown somewhat since the 1st edition in 2014, e.g., Ehlers-Danlos syndrome has now 13 entities. A brand new syndrome, Meester Loeys syndrome carrying the name of Bart Loeys was added as a companion to Loeys-Dietz syndrome. Numerous variations of cutis laxa and joint mobility disorders have been discovered taking advantage of recent advancements in genetic analysis. We have acquired better understanding of pathogenesis and biochemical changes in some other, more established entities, such as Marfan and collagen VI myopathies where better management and possible treatment are on the horizon. Even in the case of connective tissue diseases in domestic animals some progress has been made. All these updates were contributed by a group of distinguished and preeminent physicians and scientists, all of them not just working in the field but making new discoveries described by them. Readers will notice that seemingly there is an overlap among many of these disorders. And indeed, many of them, if not most are interconnected because of the prominent roles of TGFβ, of fibrillin microfibrils and collagen fibril assembly (and other molecules) playing in connective tissues physiology, and by extension in pathogenesis of many disorders described in the book. What I found particularly helpful that author(s) of each chapter bring their own perspective even when described closely related mechanism of the disease. These observations should help with diagnosis and management of such cases. The first chapters are more general, concentrating more on the physiology, structure and biochemistry of normal soft tissues. That should help in better understanding of the pathophysiology. Last but not least, the chapters are very readable, more like detective stories than dry description of genetic/biochemical defects. I do hope that basic scientists and clinicians with similar and diverse interests alike will appreciate this volume and will be inspired by it to develop their research in the field.
    Type of Medium: Online Resource
    Pages: IX, 343 p. 1 illus. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030806149
    Series Statement: Advances in Experimental Medicine and Biology, 1348
    DDC: 610.72
    Language: English
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  • 83
    Keywords: Medicine Research. ; Biology Research. ; Virology. ; Clinical medicine Research. ; Epidemiology. ; Public health. ; Biomedical Research. ; Virology. ; Clinical Research. ; Epidemiology. ; Public Health.
    Description / Table of Contents: Clinical features, diagnostic evaluation and management of COVID-19 patients -- Outbreak of COVID-19: A Detailed Overview and Its Consequences -- A paradigm gap in host-pathogen interaction studies: Lesson from the COVID-19 pandemic -- SARS/CoV-2: Behavioral Host Manipulation -- Management of COVID-19 in the Intensive Care Unit -- First wave of Covid-19 pandemic in Italy: data and evidence -- Risk factors for COVID-19: diabetes, hypertension and obesity -- Current challenges for the effective management of the COVID-19 pandemic -- COVID-19 Outbreak Challenges in Indian Migrant Pregnant and Lactating Mothers: Learnt Lesson Demands Phronesis and Hierarchical Strategies for Such Future Pandemics -- COVID-19 and Extracorporeal Membrane Oxygenation -- COVID-19's Clinical-Pathological Evidence in Relation to its Repercussion on the Central and Peripheral Nervous System -- Anatomopathological Aspects and Clinical Correlation of COVID-19: A Systematic Review -- SARS-CoV-2 liability: the hidden mystery behind its presentation in children.
    Abstract: The book Coronavirus Therapeutics Volume II provides the most comprehensive review on contemporary knowledge on the consequences during the outbreak of Coronavirus. This also describes the clinical features, diagnostic evaluation and management of Coronavirus patients. Using an integrative approach to the understanding of paradigm gap in host-pathogen interaction studies to the management of Coronavirus patients in the Intensive Care Unit to the current challenges for the effective management of Coronavirus pandemic risk factors including diabetes, hypertension, obesity and repercussion on the central and peripheral nervous system. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 241 p. 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851132
    Series Statement: Advances in Experimental Medicine and Biology, 1353
    DDC: 610.72
    Language: English
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  • 84
    Keywords: Medicine Research. ; Biology Research. ; Virology. ; Clinical medicine Research. ; Epidemiology. ; Biomedical Research. ; Virology. ; Clinical Research. ; Epidemiology.
    Description / Table of Contents: Origin and structural biology of Novel Coronavirus (SARS-CoV-2) -- The Molecular Virology of Coronaviruses with Special Reference to SARS-CoV-2 -- Epidemiology, transmission and molecular immunopathology of SARS-CoV-2 -- Epidemiology and Etiopathogeny of Covid-19 -- Immunological and Hematological Response in COVID-19 -- Toll-like receptors (TLRs) as Therapeutic Targets for Treating SARS-CoV-2: An Immunobiological Perspective -- Potential drug strategies to target Coronaviruses -- Possible therapeutic intervention strategies for COVID-19 by manipulating the cellular proteostasis network -- The potential impact of statins in the treatment of patients with COVID-19 infection -- Anticoronavirus activity of water-soluble pristine C60 fullerenes: in vitro and in silico screening -- Application of Nanoscale materials and nanotechnology against viral infection: A special focus on Coronaviruses -- Obesity: A Risk Factor for Covid-19 -- Cytokine Storm and Failed Resolution in COVID-19: Taking Cue from Multiple Sclerosis.
    Abstract: The book Coronavirus Therapeutics Volume I provides the most comprehensive review on contemporary knowledge on the origin, structural biology and molecular aspects of Coronaviruses. It also describes the etiology and pathogeny and therapeutic targets including vaccine drug candidates against Coronaviruses in the light of current scientific knowledge. Using an integrative approach to the understanding of Coronaviruses structure, function and immunobiology, the contributors provide a synopsis of novel mechanisms by which Coronaviruses can be treated. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 222 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851095
    Series Statement: Advances in Experimental Medicine and Biology, 1352
    DDC: 610.72
    Language: English
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  • 85
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Proteins . ; Cytology. ; Biomedical Research. ; Protein Biochemistry. ; Cell Biology.
    Description / Table of Contents: Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and Cancer Immunotherapy -- Chaperonin Hsp60 and Cancer Therapies -- Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment -- Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics -- Multifaceted Roles of Heat Shock Factor 1 (HSF1) in Cancer -- Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer -- Heat Shock Proteins in Atrial Fibrillation -- Threading Microarrays into Novel Applications -- Regulation of Kaposi’s Sarcoma-associated Herpesvirus Biology by Host Molecular Chaperones -- Role of Heat Shock Factors in Diseases and Immunity -- Heat Shock Proteins and Pain -- Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway -- Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with diverse Cellular and Molecular Functions -- Roles of Heat Shock Proteins on Antigen Presentation -- Heat shock proteins mediate anastasis and plasticity of thermotolerant cells.
    Abstract: The book Heat Shock Proteins in Human Diseases provides the most comprehensive review on contemporary knowledge on the role of heat shock proteins (HSP) in various types of human diseases including cancer, cardiovascular disease, microbiology and inflammation. These diseases were specifically chosen due to their dismal prognosis, the survival benefit offered by the current standards do not greatly impact the overall survival statistics with the disease and are associated with toxicity. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in human diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 297 p. 31 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030622893
    Series Statement: Heat Shock Proteins, 21
    DDC: 610.72
    Language: English
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  • 86
    Keywords: Medicine Research. ; Biology Research. ; Pharmacology. ; Drug delivery systems. ; Regenerative medicine. ; Biomedical Research. ; Pharmacology. ; Drug Delivery. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Approaches Towards Synthetic Signal Transduction in Phospholipid Bilayers -- Development of Novel Versatile Theranostic Platforms Based on Titanate Nanotubes: Towards Safe Nanocarriers for Biomedical Applications -- Metal-organic Framework—Polymer Mixed-Matrix Membranes -- Insights into Adaptive Selforganized Supramolecular Structures from Molecular Modeling and Visualization -- Self-Assembled Metallacages as Drug Delivery Systems: Design Concepts and Challenge -- Functional Microporous Polymer Networks: Synthesis and Applications -- A Story on Carbon Dioxide and its Hydration -- Inverse Design and Hierarchical Multiscale Modelling of Biological Matter -- DNA-Directed Self-assembly of Macromolecular Structures -- Luminescent Complexes and their Assemblies : from Understanding to Artificial Virus -- Tailor-Made Polymers and Nanoparticles for Applications in Nanomedicine -- Squalene-based Nanomedicines : An Original and Efficient Approach for the Treatment of Neurological Disorders without Crossing the Blood-Brain Barrier -- Biodegradable Nanoparticles for Specific Drug Transport -- Multivalent rotaxanes designed as antibiofilm agents -- Measuring Ionic Transport through Lipid Bilayers -- Polymeric Carriers for Transporting Nucleic Acids - Contributions to the Field -- Smart Polymeric Materials for Drug Delivery -- Supramolecular Guanosine-quadruplex Hydrogels and Hydrogel Composites for Cell Growth Applications -- Hydrogelation of Chitosan with Monoaldehydes towards Biomaterials with Tuned Properties -- Inorganic Nanoarticles as Free Radical Scavengers -- A Microbiological Epilogue - Nosocomial Infections -- Molecular Dynamic Simulations and In Silico Analysis of Supramolecular Self-Assembled Structures -- Validation of the Non Toxicity of Non Viral Genetic -- Kinetics Transport of Ions/Water Through Nano-Scale Channels : Review And Update.
    Abstract: This contributed volume applies the insights of supramolecular chemistry to biomedical applications such as ions/water transport through nano-scale channels, gene therapy, tissue engineering and drug delivery, to cite some of the major investigations. The challenge is to understand the mechanisms of transport through tissues particularly in the therapeutic treatment of a disease where the active drug must be delivered directly to diseased cells without affecting healthy cells. As a result, smaller quantities of active substances can be used to treat the disease. Another interest concerns new ways to administer gene therapy. If genes are often delivered to their target cells by adapted viruses, the supramolecular non-viral ‘vectors’ using dynamic nano-frameworks and nano-structures are presented. In addition, it is important to reconstruct damaged tissues by mimicking natural processes in cells and polymers, such as tissue engineering and self-healing. Different options are here discussed: e.g. hydrogels based on chitosan, a carbohydrate polymer, are proving especially promising for tissue engineering and drug delivery. For controlled delivery of drugs or other biologically active compounds, hydrogels sensitive to the most important stimuli in the human body, such as temperature, pH, ionic strength, glucose and biomolecules released by the organism in pathological conditions have been developed. Finally, to assist and validate the experimental studies, computer modelling and simulations of large-sized molecular structures and systems using different molecular dynamics and quantum mechanical techniques are developed based on the experimental and chemistry synthesis. This book is of great interest for graduate students, researchers and health professionals interested in acquiring a better understanding of the mechanisms of medical treatments. In addition, it provides numerous tools to develop better therapies for human diseases.
    Type of Medium: Online Resource
    Pages: XII, 371 p. 174 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030574567
    DDC: 610.72
    Language: English
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  • 87
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Artificial intelligence. ; Bioinformatics. ; Biomedical Research. ; Artificial Intelligence. ; Bioinformatics.
    Description / Table of Contents: 1-Dimensional Convolution Neural Network Classification Technique for Gene Expression Data -- Classification of Sequences with Deep Artificial Neural Networks: Representation and Architectural Issues -- A Deep Learning Model for MicroRNA-Target Binding -- Recurrent Neural Networks Architectures for Accidental Fall Detection on Wearable Embedded Devices -- Medical Image Retrieval System using Deep Learning Techniques -- Medical Image Fusion using Deep Learning -- Deep Learning for Histopathological Image Analysis -- Innovative Deep Learning Approach for Biomedical Data Instantiation and Visualization -- Convolutional Neural Networks in Advanced Biomedical Imaging Applications -- Deep Learning for Lung Disease Detection from Chest X-Rays Images -- Deep Learning in Multi-Omics Data Integration in Cancer Diagnostic -- Using Deep Learning with Canadian Primary Care Data for Disease Diagnosis -- Brain Tumor Segmentation and Surveillance with Deep Artificial Neural Networks.
    Abstract: This book is the first overview on Deep Learning (DL) for biomedical data analysis. It surveys the most recent techniques and approaches in this field, with both a broad coverage and enough depth to be of practical use to working professionals. This book offers enough fundamental and technical information on these techniques, approaches and the related problems without overcrowding the reader's head. It presents the results of the latest investigations in the field of DL for biomedical data analysis. The techniques and approaches presented in this book deal with the most important and/or the newest topics encountered in this field. They combine fundamental theory of Artificial Intelligence (AI), Machine Learning (ML) and DL with practical applications in Biology and Medicine. Certainly, the list of topics covered in this book is not exhaustive but these topics will shed light on the implications of the presented techniques and approaches on other topics in biomedical data analysis. The book finds a balance between theoretical and practical coverage of a wide range of issues in the field of biomedical data analysis, thanks to DL. The few published books on DL for biomedical data analysis either focus on specific topics or lack technical depth. The chapters presented in this book were selected for quality and relevance. The book also presents experiments that provide qualitative and quantitative overviews in the field of biomedical data analysis. The reader will require some familiarity with AI, ML and DL and will learn about techniques and approaches that deal with the most important and/or the newest topics encountered in the field of DL for biomedical data analysis. He/she will discover both the fundamentals behind DL techniques and approaches, and their applications on biomedical data. This book can also serve as a reference book for graduate courses in Bioinformatics, AI, ML and DL. The book aims not only at professional researchers and practitioners but also graduate students, senior undergraduate students and young researchers. This book will certainly show the way to new techniques and approaches to make new discoveries.
    Type of Medium: Online Resource
    Pages: VI, 359 p. 130 illus., 40 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030716769
    DDC: 610.72
    Language: English
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  • 88
    Keywords: Medicine Research. ; Biology Research. ; Urology. ; Reproductive health. ; Biomedical Research. ; Urology. ; Reproductive Medicine.
    Description / Table of Contents: Section I – Introduction to Spermatology Symposium -- Chapter 1. The XIIIth International Symposium on Spermatology -- Chapter 2. Fifty Years of the Spermatology Symposium -- Chapter 3. Spermatology in Sweden -- Section II – Are Sperm at the Verge of Extinction? -- Chapter 4. Temporal trends in human sperm counts: Findings and implications -- `Chapter 5. Is Decreasing Sperm Concentrations a Sign of a General Decay in Fertility Potential? -- Chapter 6. Environmental toxicants and sperm production in men and animals -- Section III – Sperm DNA – protection and delivery of a complete and undamaged genome? -- Chapter 7. Post-testicular sperm DNA oxidation: what to be afraid of? -- Chapter 8. Sperm as a possible source of transgenerational epimutations and genetic instability -- Chapter 9. Complex population of chromatin-associated proteins identified in mature sperm of the European sea bass (Dicentrarchuslabrax) through high-throughput proteomic analysis -- Chapter 10. Does Cinnamtannin B-1 protects or destabilize sperm DNA? Contradictory results of SCSA® and TUNEL Invited presentations -- Chapter 11. Peripubertal serum dioxin concentrations and sperm methylome of young Russian adults -- Chapter 12. Sperm DNA fragmentation in human split ejaculates -- Section IV - Sperm Competition, Evolution and Sperm-Egg Interaction -- Chapter 13. The sexual cascade: evolutionary dynamics of sperm competition -- Chapter 14. Genotype-phenotype associations in relation to evolution of sperm form and function -- Chapter 15. From mouse to human: New aspects of sperm transport and fertilization using cutting edge technologies -- Chapter 16. First Snapshot of How Sperm Binds the Egg at the Molecular Level -- Chapter 17. The Typical and Atypical Centrioles and Their Potential Roles in the Sperm and Embryo -- Chapter 18. Adaptive modifications of the regulation of sperm motility in the diversification of reproductive modes of amphibians -- Section V - Genetic aspects of sperm production and performance and its effects on the offspring -- Chapter 19. When cilia go bad - the complex genetics of ciliopathies -- Chapter 20. Within-Ejaculate Sperm Selection and its Implications for Assisted Reproduction Technologies -- Chapter 21. Requirements for informative and robust computational measures of sperm motility -- Chapter 22. Effect of cryopreservation on the genome of sperm in animal and humans -- Chapter 23. Mutations in the CFAP-coding Genes Lead to Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella -- Chapter 24. The mouse-specific Gly-to-Cys mutation in mammalian acrosin is a cause of impairment in proteolytic activity -- Chapter 25. Chemical and genetic approaches to identify C. elegans spermiogenesis-related factors -- Section V -CASA - Advances and Challenges -- Chapter 26. CASA in the clinical andrology laboratory -- Chapter 27. Process and Data Management of Casa in Animal Spermatozoa -- Chapter 28. Relationship between flagellar movement and head trajectory at higher frame rates-is this still a valid approach for CASA? -- Chapter 29. CASA a Suitable tool for epidemiology and reprotox studies -- Section VI -Challenges for Sperm Function In Vitro -- Chapter 30. Common challenges for sperm in vitro- causes and consequences -- Chapter 31. Main effects of in vitro manipulation of spermatozoa -- Chapter 32. Effect of Melatonin on Capacitation and Ca2+ Distribution in Red Deer Spermatozoa -- Chapter 33. Unravelling the signal transduction pathways of novel mitochondrial peroxiporins in activated piscine spermatozoa -- Chapter 34. Prolonged chilled preservation and preliminary investigations of energy production of koala (Phascolarctos cinereus) spermatozoa -- Chapter 35. Sperm motion and metabolism in physiological conditions -- Chapter 36. Gametes collision in fresh water fish: evidences of guidance and selection -- Chapter 37. Lectin-binding pattern changes on the bovine sperm after differently induced process of capacitation -- Section VII -Heterogeneity of Sperm Morphology and Laboratory Techniques to Overcome Assessment Challenges -- Chapter 38. Have we conquered sperm morphology analysis in different mammalian species as analysed by CASMA? -- Chapter 39. Progress with sperm morphology evaluation after the strict criteria prognosis groups era due to the introduction of the new lower reference limit values for semen parameters of the 2010 WHO manual -- Chapter 40. A structured assessment for the assessment of human sperm morphology -- Chapter 41. On the Indispensability for Standardization of the Basic Examination of Human Semen -- Chapter 42. A simple but dramatic technical improvement in the Diff Quik stain protocol used for preparing specimens for sperm morphology evaluation (Improved Diff Quik stain protocol for preparation of sperm morphology evaluation specimens) -- Section VII - Fertility and Infertility -- Chapter 43. Intracellular Viruses Identification in Sperm Assay of Patients with Fertility problems -- Chapter 44. Association between vitamin D intake and vitamin D status with semen parameters among young men in Southern Spain -- Chapter 45. Single cell analysis of intracellular calcium signalling of patient sperm and its relation to IVF success -- Chapter 46. Sperm from a patient with a homozygous in-frame deletion in CATSPERE lack functional CatSper expression and fail to fertilise at IVF -- Chapter 47. Changes in pattern of protein phosphorylation in bull testicular and epididymal sperm -- Chapter 48. Proteomics and biomarker identification in improved sperm motility parameters after 4 h of ejaculatory abstinence -- Chapter 49. HSP90A may control spermatogenesis of Asian elephant (Elephas maximus) cryptorchid testes -- Chapter 50. Improved sperm function in human sperm subpopulations: a model for studying subfertility -- Chapter 51. Absence of BSP protein have not important effect on male infertility. .
    Abstract: This Symposium had 7 main themes with invited speakers, 17 free oral presentations and 44 poster presentations. Morning sessions were separated from afternoon sessions by a two-hour lunch break to inspire to spontaneous interaction between participants. The long, bright evenings of early May with a generous weather also contributed to the intended atmosphere of scientific and social interchange. Themes Are Sperm at the Verge of Extinction? Sperm DNA – protection and deliv­ery of a complete and undamaged genome Sperm Competition, Evolution and Sperm-Egg Interaction Genetic aspects of sperm production and performance and its effects on the offspring CASA - Advances and Challenges Challenges for Sperm Function In Vitro Heterogeneity of Sperm Morphology and Laboratory Techniques to Overcome Assessment Challenges Sperm Motility (Free Poster Theme) Fertility and Infertility (Free Poster Theme).
    Type of Medium: Online Resource
    Pages: X, 370 p. 72 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030662929
    DDC: 610.72
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Respiratory organs Diseases. ; Respiratory organs. ; Physiology. ; Immunology. ; Inflammation. ; Biomedical Research. ; Pneumology. ; Respiratory Physiology. ; Immunology. ; Inflammation.
    Description / Table of Contents: Overload of Medical Documentation: A Disincentive for Healthcare Professionals -- Epidemiologic Benefits of Pneumococcal Vaccine Introduction into Preventive Vaccination Programs -- Serum Vitamin D and Immunogenicity of Influenza Vaccination in the Elderly -- Influenza A (H1N1) and Respiratory Syncytial Virus (RSV) Coinfection in a Newborn Child: A Case Report -- Thoracic Manifestation of Granulomatosis with Polyangiitis: A Case Report -- The Natural Course of Impaired Fasting Glucose -- Oleosins: A Short Allergy Review -- Shortage of Physicians: A Critical Review -- Fluid Therapy in Patients Undergoing Abdominal Surgery: A Bumpy Road Towards Individualized Management -- Manual Pressure Release and Low-Grade Electrical Peripheral Receptor Stimulation in Nonspecific Low Back Pain: A Randomized Controlled Trial -- Human Inhalation Study with Zinc Oxide: Analysis of Zinc Levels and Biomarkers in Exhaled Breath Condensate. Cognitive Function After Lung Transplantation.
    Abstract: This volume is dedicated to multidisciplinary research at the interface between basic biomedicine and clinical practice. This book guides best practice in the diagnosis and therapy while dealing with difficult-to-treat disorders of yet unclear etiology. Chapters address such disorders as granulomatosis with polyangiitis causing autoimmune-related multiorgan inflammation of blood vessels, increasingly widespread allergy to peanuts, occupational exposure to zinc oxide, and immunogenic responses to pneumococcal and influenza vaccination underlying their preventive effectiveness. Other hot issues deal with the proper use of fluid therapy in the perioperative period and a cognitive decline in lung transplant patients. A new physiotherapeutic approach of treating key myofascial trigger points in low-back pain appears highly beneficial in reducing patients’ disability, advancing physiotherapy of this overwhelming condition. Finally, other chapters consider ways to streamline medical management to increase the number of physicians and their availability for patients, a particularly sensitive issue in the current COVID-19 pandemic. The dissemination of clinical knowledge about high-risk and hardly controllable conditions is an inalienable part of progress in medical practice. The book is a resource for clinical specialists, general practitioners, and allied healthcare professionals.
    Type of Medium: Online Resource
    Pages: VI, 101 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030702069
    Series Statement: Clinical and Experimental Biomedicine, 1324
    DDC: 610.72
    Language: English
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  • 90
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    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Cytology. ; Lipids. ; Biomedical Research. ; Medical Genetics. ; Cell Biology. ; Cell Biology. ; Lipidology.
    Description / Table of Contents: Foreword -- Ferroptosis: Concepts and Definitions -- Overcoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT inhibitors -- Iron Homeostasis and Metabolism: Two Sides of a Coin -- The Role of NCOA4-mediated Ferritinophagy in Ferroptosis -- Emerging Role for Ferroptosis in Infectious Diseases -- Small Molecule Regulators of Ferroptosis -- Necroptosis, The other main Caspase-Independent Cell Death.
    Abstract: This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron metabolism and its connection to ferritinophagy, a ferritin selective autophagy, with profound implications in neurodegenerative diseases such as Alzheimer, Parkinson, Huntington and ALS. Lastly, it describes necroptosis, another important form of cell death, along with its connections to human disorders and potential crosstalk with ferroptosis. While covering basic concepts, the book delves into mechanisms and modulation of ferroptosis for treating a wide variety of human diseases thus offering a valuable and informative resource for both, scientists and clinical researchers.
    Type of Medium: Online Resource
    Pages: IX, 140 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030620264
    Series Statement: Advances in Experimental Medicine and Biology, 1301
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Neurosciences. ; Biomedical Research. ; Neuroscience.
    Description / Table of Contents: Constituents of Cannabis Sativa -- Synthetic and Natural Derivatives of Cannabidiol -- Clinical Pharmacokinetics of Cannabinoids and Potential Drug-Drug Interactions -- Cannabinoid Receptors and Ligands: Lessions from CNS Disorders and the Quest for Novel Treatment Venues -- Sleep-Wake Neurobiology -- Cannabinoids and Sleep/Wake Control -- Effects of Cannabinoid Agonists and Antagonists on Sleep in Laboratory Animals -- Modulation of Noradrenergic and Serotonergic Systems by Cannabinoids: Electrophysiological, Neurochemical and Behavioral Evidence -- Natural Cannabinoids as Templates for Sleep Disturbances Treatment -- The Effect of Cannabinoids on the Brain´s Circadian Clock -- Effects of Cannabis Consumption on Sleep -- Addiction and Sleep Disorders -- Cannabis for Restless Legs Syndrome.
    Abstract: Research on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.
    Type of Medium: Online Resource
    Pages: XXII, 183 p. 37 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030616632
    Series Statement: Advances in Experimental Medicine and Biology, 1297
    DDC: 610.72
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Arts. ; Artificial intelligence. ; Knowledge, Theory of. ; Biomedical Research. ; Arts. ; Artificial Intelligence. ; Epistemology.
    Description / Table of Contents: Introduction on Integrated Science: Science without Borders -- The Human Person as an Integrated System -- On the Nature of Qualitative Research in Process Transformations: The Changing Man in the Changing World.-Integrated Science: Ambitions, Practicalities, Misunderstandings -- The Integration of the Sciences and Integral Human Knowledge -- The Indelible Stamp of Lowly Origins: An Epistemic Architecture between the Sciences and Humanities -- Transdisciplinary Science: Integration or Systematic, Strategic and Catalytic Knowledge -- Models and Integration -- Unlaws: the Missing “Dark Matter” in the Philosophy of Science -- Life - Stabilization of the Unstable through Controlling Influence of Quantum Information -- The Sustainable Humanist Concept in Art and Science Synergies -- From Being One to Being Many. Understanding the Diversity of Bio‐Life: Human, Nonhuman and Liminal Beings in the in Bio Art and Body Art -- Composite Bodies in Times of Catastrophe. On Socio‐Material Assemblies, Affective Contagions and the Biodegradable -- Life, Complexity, Communication: Integrating Social Systems Theory and Consciousness -- Rethinking the Reverse Side of Artificial Intelligence -- The Question of Transdisciplinarity between Modern Science and Critical Thought -- Adaptive Networks at the Crossroad of Artificial Intelligence and Formal, Biological, Medical and Social Sciences -- Are We Ready for "Them" Now? The Relationship between Human and Humanoid Robots -- Integrating Computer Simulation and Social Theory for Planning and Managing Complex Problems -- Rethinking Managerial Control in the Contemporary Context -- Innovation and Altruism: A New Paradigm Defining the Survival of Corporations -- Integrated Science 2050: Science without Borders.
    Abstract: The INTEGRATED SCIENCE Book series aims to publish the results of the most updated ideas and reviews in transdisciplinarity fields, to highlight the integration of different disciplines, including formal sciences, physical-chemical sciences, engineering, biological sciences, medical sciences, and social sciences. The whole world is suffering from complex problems; these are borderless problems; so, a borderless solution could be the solution for such complex problems. The “INTEGRATED SCIENCE: Science without Borders” is the first volume of the INTEGRATED SCIENCE Book series. It focuses on the human as an integrated system and finding solutions for the problems facing humanity. For its purpose, it introduces a kind of science, which is called integrated science and portrays results from every effort trying to integrate separate subjects. Integration of science with integral human knowledge, ancient science with modern science, and quantity with quality are a few examples of such efforts. Some difficulty might, however, lie in integrating knowledge systems. In this edited book, art and artificial intelligence reveal to us their different methods of work to overcome ambitions and become applicable to the world system full of unpredictable challenges. Art offers a lens to see the beauty of infinite complexity. The resultant artistic background would permit the perfect programming and bioengineering of biological systems, which we could never do by direct eye viewing. Networking is the spot where the crossing of formal, biological, medical, and social sciences with artificial intelligence takes place. By working within a network, individual thinking to the old unresolved problems reduces to simulation and bioengineering, a relatively effortless route for innovation, creativity, and altruism. In this manner, it would be understandable that there is an obvious way to speed up the growth of science – that is, moving on the edge of the intersection between knowledge-based systems. The INTEGRATED SCIENCE Book series is to provide an overview of the essential elements of integrated science. The unique aspect of this series, privileging it from other books, is covering all aspects of science as a true one nature.
    Type of Medium: Online Resource
    Pages: XVIII, 495 p. 112 illus., 97 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030652739
    Series Statement: Integrated Science, 1
    DDC: 610.72
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Vocational guidance. ; School management and organization. ; School administration. ; Career education. ; Biomedical Research. ; Career Counseling. ; Organization and Leadership. ; Career Skills.
    Description / Table of Contents: Chapter 1: “Carving Your Own Path” – shaping your scientific identity -- Chapter 2: The Two Cornerstones of Academic Research: Writing Grant Applications and Publications -- Chapter 3: Setting up a Successful Research Group -- Chapter 4: Leading Your Research Group as a Principal Investigator -- Chapter 5: The Daily Work of Principal Investigators -- Chapter 6: Dealing with Failure and Stress in Academic Research -- Chapter 7: Thoughts of Principal Investigators about Work, Science, and Themselves -- Chapter 8: Under the Hood – Common Thinking Patterns of Principal Investigators -- Chapter 9: Epilogue -- Chapter 10: Methods.
    Abstract: Pursuing a career in biomedical research can be daunting, considering the stiffer competition and uncertain career prospects in academia. This book summarizes career advice gathered during in-depth interviews with 106 biomedical scientists who lead their own laboratories. The participating principal investigators are from 44 research institutions in 11 countries. This book is unique in that it provides a glimpse into the mindset of principal investigators. Here, the reader will learn about common thought patterns and values, as well as the range of opinions and ways of thinking to be found among a large group of active principal investigators – without having to read more than a hundred individual autobiographies. The book will benefit all PhD students who want to learn more about their supervisor’s mindset in order to successfully complete their projects. It can help freshly graduated PhDs planning to pursue an academic career, and MDs contemplating a career in research, to decide whether they truly want to embark on this path. Lastly, it can offer young principal investigators a source of inspiration on how to succeed and achieve their goals.
    Type of Medium: Online Resource
    Pages: XIX, 209 p. 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030855710
    DDC: 610.72
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Internal medicine. ; Biomedical Research. ; Internal Medicine.
    Description / Table of Contents: Introduction. --Part 1 -- Chapter 1. Role of Par-4 in lung cancer -- Chapter 2. Prostate apoptosis response-4 in nasopharyngeal carcinoma -- Chapter 3. Role of Par-4 in Chemoresistance and targeted therapies in ovarian and endometrial cancers -- Chapter 4. Regulation of Par-4 and role in GI tumors -- Chapter 5. Role of Par-4 in prostate cancer -- Chapter 6. Activation of apoptosis by Par-4 in pancreatic cancer -- Chapter 7. Role of Par-4 and GRP78 in Glioblastoma -- Chapter 8. Role of Par-4 in breast cancer recurrence -- Chapter 9. Involvement of Par-4 in breast cancer -- Chapter 10. Role of endogenous Par-4 in CLL -- Chapter 11. Role of Par-4 in inhibition of TCL1 induced growth -- Chapter 12. Par-4/THAP in survival of T-cell acute lympoblastic leukemia cells -- Chapter 13. Par-4 expression in cholangiocarcinoma -- Chapter 14. Par-4 suppresses breast cancer growth and invasion of breast cancer cells -- Chapter 15. PAWR as direct SRC-1/HOXC11 suppression target -- Chapter 16. Par-4 cleavage is required for TNF induced apoptosis -- Chapter 17. Par-4 secretagogues -- Chapter 18. Recombinant production and characterization of SAC -- Chapter 19. Anti-tumor effects of plant derived Par-4 -- Chapter 20. Par-4 in Mycobacterium tuberculosis Infected Macrophages -- Part 2 - Role in other Diseases -- Chapter 21. Role of Par-4 in ceramide inducible effects in neurons -- Chapter 22. Role of Par-4 in Alzheimers disease -- Chapter 23. Dopamine signaling in association with induction of Par-4 protein expression -- Chapter 24. Par-4 (PAWR) in major depressive disorder -- Chapter 25. Par-4 dependent apoptosis of islet β cells in type 2 diabetes -- Chapter 26. Par-4 in cardiac fibroblast senescence -- Chapter 27. Par-4 in ocular development and disease -- Chapter 28. Par-4 in apoptosis during human salivary gland development -- Chapter 29. Suppression of Par-4 protects human renal proximal tubule cells from apoptosis -- Chapter 30. Lessons from knockout mice -- Part 3 - From Bench to Bedside -- Chapter 31. Par-4 secretagogues in clinical trials -- Chapter 32. Potential of Par-4 as a therapeutic target for cancer.
    Abstract: Par-4 is a naturally occurring tumor suppressor. Studies have indicated that overexpression of Par-4 selectively induces apoptosis in cancer cells while leaving normal, health, cells unaffected. Mechanisms contributing to this cancer-selective action of Par-4 have been associated with PKA activation of intracellular Par-4 in cancer cells or GRP78 expression primarily on the surface of cancer cells. On the other hand, endogenous Par-4 sensitizes cells to the action of a broad range of apoptotic inducers acting via the extrinsic and intrinsic pathways. A number of binding partners of Par-4 have been identified and shown to regulate Par-4 function in cancer and other diseases, such as Alzheimer’s and major depression. Recent studies have recognized a number of natural products, dietary supplements, synthetic molecules and FDA-approved drugs that induce the secretion of Par-4 protein to cause apoptosis in primary or metastatic tumors, one of which is in clinical trials. More than 50 different laboratories worldwide are involved in Par-4 based research of this unique protein that has progressed from the bench to clinical trials. This second, companion volume will provide a comprehensive overview of Par-4’s role in cancer and other diseases. Chapters are written by leading researchers, and will be useful for a broad audience across the scientific community, particularly students and trainees, who are the next generation of scientists and clinicians to participate in new studies and discoveries on Par-4.
    Type of Medium: Online Resource
    Pages: X, 331 p. 121 illus., 93 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030805586
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Pharmacology. ; Human physiology. ; Internal medicine. ; Physiology. ; Biomedical Research. ; Medical Biochemistry. ; Pharmacology. ; Human Physiology. ; Internal Medicine. ; Physiology.
    Description / Table of Contents: Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression -- Ion Channel Profiling in Prostate Cancer: Toward Cell Population-Specific Screening -- Ion channels in Lung Cancer -- Contribution and Expression of Organic Cation Transporters and Aquaporin Water Channels in Renal Cancer -- Transportome Malfunctions and the Hallmarks of Pancreatic Cancer -- How Dysregulated Ion Channels and Transporters Take a Hand in Esophageal, Liver, and Colorectal Cancer -- Ion Channels in Glioma Malignancy -- Membrane Transporters and Channels in Melanoma -- Ion Channel Dysregulation in Head and Neck Cancers: Perspectives for Clinical Application.
    Abstract: Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression Halima Ouadid-Ahidouch, Hamid Morjani, Julie Schnipper, Alban Girault, and Ahmed Ahidouch Ion Channel Profiling in Prostate Cancer: Toward Cell Population-Specific Screening Valerio Farfariello, Natalia Prevarskaya, and Dimitra Gkika Ion Channels in Lung Cancer Etmar Bulk, Luca Matteo Todesca, and Albrecht Schwab Contribution and Expression of Organic Cation Transporters and Aquaporin Water Channels in Renal Cancer Giuliano Ciarimboli, Gerit Theil, Joanna Bialek, and Bayram Edemir Transportome Malfunctions and the Hallmarks of Pancreatic Cancer Qi Ling and Holger Kalthoff How Dysregulated Ion Channels and Transporters Take a Hand in Esophageal, Liver, and Colorectal Cancer Christian Stock Ion Channels in Glioma Malignancy Luigi Catacuzzeno, Luigi Sforna, Vincenzo Esposito, Cristina Limatola, and Fabio Franciolini Membrane Transporters and Channels in Melanoma Ines Böhme, Roland Schönherr, Jürgen Eberle, and Anja Katrin Bosserhoff Ion Channel Dysregulation in Head and Neck Cancers: Perspectives for Clinical Application Nagore Del-Río-Ibisate, Rocío Granda-Díaz, Juan P. Rodrigo, Sofía T. Menéndez, and Juana M. García-Pedrero.
    Type of Medium: Online Resource
    Pages: IX, 427 p. 50 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030909208
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 181
    DDC: 610.72
    Language: English
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    Keywords: Medicine Research. ; Biology Research. ; Medical microbiology. ; Internal medicine. ; Biomedical Research. ; Medical Microbiology. ; Internal Medicine.
    Description / Table of Contents: 1. Inflammatory components of the thyroid cancer microenvironment - an avenue for identification of novel biomarkers -- 2. Disruption of Cell-Cell Communication in Anaplastic Thyroid Cancer as an Immunotherapeutic Opportunity -- 3. Exosomes in the Healthy and Malignant Bone Marrow Microenvironment -- 4. Structural Biology of the Tumor Microenvironment -- 5. Metabolic interactions between tumor and stromal cells in the Tumor Microenvironment -- 6. Interacting Genetic Lesions of Melanoma in the Tumor Microenvironment: Defining a Viable Therapy -- 7. Non-coding RNAs in Papillary Thyroid Cancer: Interaction with cancer associated fibroblasts (CAFs) in the Tumor Microenvironment (TME) and regulators of differentiation and Lymph Node Metastasis.
    Abstract: Over the past decade, the tumor microenvironment has become one of the most important research areas in cancer biology, as cells within the tumor microenvironment, despite being outnumbered by healthy cells, are able to evade surveillance and immune-mediated destruction. While researchers have learned a great deal about the cellular and structural makeup of the tumor microenvironment, there has been a growing understanding of the metabolic interplay between the tumor microenvironment's various cellular constituents and how each of them contributes to overall tumor growth and metastases. This new volume will guide researchers, students, oncologists and academics through a rapidly developing and changing field with a thorough understanding of tumor microenvironment biology from a cellular, structural, metabolic, and immunological perspective.
    Type of Medium: Online Resource
    Pages: XIII, 164 p. 19 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030832827
    Series Statement: Advances in Experimental Medicine and Biology, 1350
    DDC: 610.72
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Human physiology. ; Pharmacology. ; Nutrition   . ; Biomedical Research. ; Human Physiology. ; Pharmacology. ; Nutrition.
    Description / Table of Contents: 1 Introduction: Hot and Cold Theory, the Path Towards Personalized Medicine -- Part I Definitions and Beliefs -- 2 Principle of Hot and Cold and Its Clinical Application in Traditional Chinese Medicine -- 3 Principle of Hot and Cold and Its Clinical Application in Persian Medicine -- 4 Principle of Hot (Ushna) and Cold (Sheeta) and Its Clinical Application in Ayurvedic Medicine -- 5 Principle of Hot and Cold and Its Clinical Application in Latin American and Caribbean Medicines -- Part II Scientific Evidence -- 6 Hot and Cold Theory: Evidence in Nutrition -- 7 Hot and Cold Theory: Evidence in Pharmacology -- 8 Hot and Cold Theory: Evidence in Physiology -- 9 Hot and Cold Theory: Evidence in Systems Biology -- Part III Perspective -- 10 Hot and Cold Theory: A Personalized Medicine Approach -- 11 Hot and Cold Theory: Future Perspective.
    Abstract: This book is about the theory of Hot and Cold, a mutual fundamental base of traditional medicines all around the world. The theory describes the dynamic balance state of the body on the axis of hot and cold for each individual and proposes the fact that deviation from this equilibrium is a predisposing factor for diseases. Such an approach helps practitioners to provide treatments tailored to the patient’s condition, not the disease. This book, for the first time, has gathered native descriptions of Hot and Cold theory in different traditional medicines, including traditional Chinese medicine, Persian (Humoral, Unani) medicine, Ayurvedic medicine and Latin American and Caribbean medicines. After defining the common ground, contemporary research - in nutrition, pharmacology, physiology and systems biology - has been explored using scientific methodology. This work is the result of an international collaboration of more than 30 scientists and scholars with high reputations in their fields. Hot and Cold theory, as a holistic individualized approach in prevention, diagnosis and treatment, can be merged into the novel fast-paced concepts in systems biology and precision medicine. Through this bridge, the authors propose that the Hot and Cold theory should be revisited more deeply by medical scientists, who are the main audience of this book, to pave the way towards integrated holistic personalized medicine.
    Type of Medium: Online Resource
    Pages: XXIII, 174 p. 16 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030809836
    Series Statement: Advances in Experimental Medicine and Biology, 1343
    DDC: 610.72
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biology Technique. ; Regenerative medicine. ; Biomedical engineering. ; Biomedical Research. ; Cell Biology. ; Biological Techniques. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Biopharmaceuticals Produced from Cultivated Mammalian Cells -- Remote Control of Mammalian Therapeutic Designer Cells -- Next generation cell engineering using microRNAs -- An Omic’s data-driven approach towards engineering mammalian cell factories and bioprocesses for biopharmaceutical production -- Redesigning spent media from cell culture bioprocess to feed new bacterial fermentations -- Monoclonal antibody glycoengineering for biopharmaceutical quality assurance -- Next-generation cell engineering platform for improving recombinant protein production in mammalian cells -- Manufacturing human pluripotent stem cells and differentiated progenitors -- Biomanufacturing of Mesenchymal Stromal Cell for Therapeutic Applications -- Process Design for hMSC Products in Stirred Tank Bioreactors -- Bio-production of Adeno-associated virus for gene therapy -- Scale-up (and scale-down) of CHO cell culture, with a focus on how to adjust the various culture parameters/setpoints across different systems from lab-scale to manufacturing-scale -- Intensified and Continuous mAb Production with Single-Use Systems -- Mathematical modelling of cell culture processes -- Model-assisted design concepts for mammalian cell culture processes -- Bioprocess monitoring and control -- Industrial Monitoring of Cell Culture.
    Abstract: This contributed volume is dedicated towards the progress achieved within the last years in all areas of Cell Culture Engineering and Technology. It comprises contributions of active researchers in the field of cell culture development for the production of recombinant proteins, cell line development, cell therapy and gene therapy, with consideration of media development, process scale-up, reactor design, monitoring and control and model-assisted strategies for process design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. This book is conceived for graduate students, postdoctoral fellows and researchers interested in the latest developments in Cell Engineering.
    Type of Medium: Online Resource
    Pages: X, 550 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030798710
    Series Statement: Cell Engineering, 10
    DDC: 610.72
    Language: English
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  • 99
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Conservation biology. ; Ecology . ; Human geography. ; Environmental sciences. ; Physics. ; Geographical Information System. ; Conservation Biology. ; Human Geography. ; Environmental Physics.
    Description / Table of Contents: From the Contents: Geographic Settings -- Spatial Locations of Nepal (Geopolitics) -- Culture, Religion, and Natural Resources -- Population Growth, Migration and Residential Mobility (Literature review and field verifications) -- Demographic Theory and Population Growth -- Fertility, Mortality, and Demographic Transition -- Human-environment relationships -- General Theory of Development and Migration -- Political Ecology of Land Encroachment -- Concepts and Determinants of Migration.
    Abstract: This monograph examines contemporary environmental challenges facing Nepal, this landlocked country’s representativeness in the wider South Asian context is both distinct and generalizable. In large part, this is because of its extremes of physiographical structure- plains, hill ranges, mountainous massifs - and wide range of altitudinal terrains, which represent and replicate South Asian and East Asian continental conditions differing as markedly as humid tropical lowlands, sub-tropical hill ranges and temperate to sub-arctic mountainous environments. Associated forest regimes, in which deforestation and reforestation patterns have evolved in recent times, and differing densities of settlement and cleared agricultural landscapes in each of these altitudinal zones, add to the environmental diversity of Nepal. Associated fauna and exotic species are in various states of endangerment especially Bengal tigers, one horned rhinos, wild elephants, crocodile, musk deer, and peasants, to name a few- so that their forested and mountainous habitats as ‘Wild Life Reserves’ also deserve our attention, and are featured in this monograph’s remit.
    Type of Medium: Online Resource
    Pages: XXXI, 764 p. 211 illus., 169 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030501686
    Series Statement: Advances in Asian Human-Environmental Research,
    DDC: 910.285
    Language: English
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  • 100
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Agriculture. ; Sustainability. ; Geographical Information System. ; Agriculture. ; Sustainability.
    Description / Table of Contents: Chapter 1. Introduction to Agro-geoinformatics: Theory and Practices -- Chapter 2: Remote sensing for agriculture -- Chapter 3. GIS fundamentals for agriculture -- Chapter 4. Agro-geoinformatics data sources and sourcing -- Chapter 5. Standards and interoperability -- Chapter 6. Image processing methods in agricultural observation systems -- Chapter 7. Data Fusion in Agricultural Information Systems -- Chapter 8. Big Data and its Applications in Agro-Geoinformatics -- Chapter 9. Land Parcel Identification -- Chapter 10. Crop Pattern and Status Monitoring -- Chapter 11. Crop Growth Modeling and Yield Forecasting -- Chapter 12. Spatial and Temporal Monitoring System for Agriculture -- Chapter 13. Spatial Data Usage in Turkish Agriculture -- Chapter 14. Geospatial Land Use and Land Cover Data for Improving Agricultural Area Sampling Frames -- Chapter 15. Mapping and Monitoring of Soil Moisture, Evapotranspiration and Agricultural Drought -- Chapter 16. Flood Monitoring and Crop Damage Assessment -- Chapter 17. Remote sensing-based mapping of plastic-mulched landcover -- Chapter 18. Design and Implementation of Geospatial Data Services for Agriculture. .
    Abstract: This volume collects and presents the fundamentals, tools, and processes of utilizing geospatial information technologies to process remotely sensed data for use in agricultural monitoring and management. The issues related to handling digital agro-geoinformation, such as collecting (including field visits and remote sensing), processing, storing, archiving, preservation, retrieving, transmitting, accessing, visualization, analyzing, synthesizing, presenting, and disseminating agro-geoinformation have never before been systematically documented in one volume. The book is edited by International Conference on Agro-Geoinformatics organizers Dr. Liping Di (George Mason University), who coined the term “Agro-Geoinformatics” in 2012, and Dr. Berk Üstündağ (Istanbul Technical University) and are uniquely positioned to curate and edit this foundational text. The book is composed of eighteen chapters that can each stand alone but also build on each other to give the reader a comprehensive understanding of agro-geoinformatics and what the tools and processes that compose the field can accomplish. Topics covered include land parcel identification, image processing in agricultural observation systems, databasing and managing agricultural data, crop status monitoring, moisture and evapotranspiration assessment, flood damage monitoring, agricultural decision support systems and more. .
    Type of Medium: Online Resource
    Pages: VI, 418 p. 152 illus., 101 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030663872
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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