ALBERT

Description / Table of Contents: Part I: HISTORY -- Chapter 1: Transmissible Spongiform Encephalopathy: from its beginnings to Daniel Carleton Gajdusek -- Part II: GENERAL ASPECTS OF PRIONS -- Chapter 2: The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein -- Chapter 3: Mammalian Prion Structures -- Chapter 4: Insoluble Cellular Prion Protein and Other Neurodegeneration-related Misfolded Protein Aggregates in the Brain of Asymptomatic Individuals -- Part III: CONVERSION AND STRAIN OF PRIONS -- Chapter 5: Prion Conversion and Deformed Templating -- Chapter 6: Prion Strain Interference -- Chapter 7: Molecular Mechanisms Encoding Strains of Prions and Prion-Like Misfolded Proteins -- Chapter 8: Cofactor Involvement in Prion Propagation -- Chapter 9: Prion Protein Conversion and Lipids -- Part IV: ENVIRONMENT AND TRANSMISSION OF PRIONS -- Chapter 10: Prions in the Environment -- Chapter 11: Environmentally Acquired Transmissible Spongiform Encephalopathy -- Chapter 12: Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion -- Chapter 13: Species Barriers in Prion Disease -- Part V: MODELLING OF PRIONS -- Chapter 14: Modeling the Cell Biology of Prions -- Chapter 15: Transgenic Mice Modelling in Prion Diseases -- Chapter 16: Stem Cell Models in Prion Research -- Chapter 17: Drosophila Models of Prion Diseases -- Part VI: HUMAN PRION DISEASES AND OTHER PATHOLOGIES -- Chapter 18: Human Sporadic Prion Diseases -- Chapter 19 Genetic Creutzfeldt-Jakob and Gerstmann-Sträussler-Scheinker Diseases -- Chapter 20: Glycoform-selective Prions in Sporadic and Inherited Variably Protease-sensitive Prionopathies -- Chapter 21: The Spectrum of Tau Pathology in Human Prion Disease -- Chapter 22: Prion Protein Complex with mGluR5 Mediates Amyloid-ß Synaptic Loss in Alzheimer’s Disease -- Chapter 23: Prion and Cancers -- Chapter 24: Protective Role of Cellular Prion Protein in Tissue Ischemic/Reperfusion Injury -- Part VII: ANIMAL PRION DISEASES -- Chapter 25: Bovine Spongiform Encephalopathy -- Chapter 26: Classical and Atypical Scrapie in Sheep and Goats -- Chapter 27: Research models for studying chronic wasting disease -- Part VIII: YEAST PRIONS -- Chapter 28: Introduction to Yeast and Fungal Prions -- Chapter 29: Yeast Prions Are Folded, In-Register Parallel Amyloids Subject to Multiple Anti-prion Systems -- Part IX: DIAGNOSIS AND HUMAN PRION SURVEILLANCE -- Chapter 30: Real-time quaking-induced conversion (QuIC) assays for the detection and diagnosis of human prion diseases -- Chapter 31: Protein Misfolding Cyclic Amplification -- Chapter 32: Skin Misfolded Proteins as Biomarkers for Diagnosis of Prion and Prion-like Diseases -- Chapter 33: Diagnosis of Prion Disease: Conventional Approaches -- Chapter 34: Human Prion Disease Surveillance -- Part X: TREATMENT -- Chapter 35: Overview on Treatment of Prion Diseases and Decontamination of Prions -- Chapter 36: Gene Therapy Strategies for Prophylactic and Therapeutic Treatments of Human Prion Diseases -- Chapter 37: Immunomodulation.

Description / Table of Contents: Introduction to Acute, Chronic, and Episodic Pain -- Inflammation and Pain -- Animal Models of Pain and Anti-inflammatory Treatments -- Inflammatory Mediators, Nociceptors, and Their Interactions in Pain -- Immune and Glial Cells in Pain and Their Interactions with Nociceptive Neurons -- Sex Differences in Neuroimmune Interactions and Pain -- Neuroimmune Interactions in Itch -- Toll-like Receptors in Pain and Itch -- Immunotherapy and Pain -- Cell Therapy and Regenerative Pain Medicine - Preclinical Studies -- Cell-based Therapies in Pain Management -- Platelet-Rich Plasma and Autologous Conditioned Serum: Non-Cellular Biologic Therapies for Neuroimmune Modulation and the Treatment of Arthritis Pain -- Exercise and Diet in the Control of Inflammation and Pain -- Mechanism-Based Pain Therapies -- Neuromodulation in Pain Management -- What Patients Need to Know about Pain Therapy?.

Description / Table of Contents: Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure.

Description / Table of Contents: Molecular imaging of the human emotion circuit -- The neurocognitive mechanisms of unconscious emotional responses -- Social and Affective Neuroscience of Embodiment -- The neuroscience of beauty -- Mirror Neurons … in action: ERPs and neuroimaging evidence -- Sex differences in social cognition -- Development of morality and emotional processing -- Trust in Social Interaction: From Dyads to Civilizations -- The time has come to be mindwanderful: Mind wandering and the intuitive psychology mode -- Social Cognition development and socio affective dysfunction in childhood and adolescence -- Clinical neuroscience meets second-person neuropsychiatry -- EEG and ERPs in the study of Language and Social Knowledge -- fMRI and fNIRS methods for social brain studies: hyperscanning possibilities -- Modulating the Social and Affective Brain with transcranial stimulation techniques -- What our eyes can tell us about our social and affective brain? -- Facial EMG – Investigating the interplay of facial muscles and emotions.

Description / Table of Contents: An overview of genome editing in cardiovascular and metabolic diseases -- Bioinformatics research methodology of genome editing in cardiovascular and metabolic diseases -- Online databases of genome editing in cardiovascular and metabolic diseases -- Application of systems biology for genome editing involved in regulating of cardiovascular and metabolic diseases -- Bioinformatics for reducing off-targets in cardiovascular and metabolic diseases -- Genome editing and cardiac regeneration -- Genome editing and myocardial development -- Genome editing and heart failure -- Genome editing and pathological cardiac hypertrophy -- Genome editing and cardiac remodeling -- Genome editing and diabetic cardiomyopathy -- Genome editing and cardiac arrhythmias -- Genome editing and atrial fibrillation -- Genome editing and muscle atrophy -- Genome editing and obesity -- Genome editing and fatty liver -- Genome editing and diabetes -- Genome editing and gout -- Genome editing and protein energy malnutrition -- Genome therapy and cardiovascular diseases -- Therapeutics in metabolic diseases -- Gene editing and human iPSCs in cardiovascular and editing diseases -- Prospective advances in genome editing investigation.

Description / Table of Contents: Chapter 1: Why study Drug Resistant Epilepsy? -- Chapter 2: Pharmacoresistance in Epilepsy -- Chapter 3: Experimental models for the study of drug-resistant epilepsy -- Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy -- Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy -- Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level? -- Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy -- Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy -- Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy -- Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy -- Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP -- Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance -- Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance -- Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration -- Chapter 15: Application of proteomics in the study of molecular markers in epilepsy -- Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies -- Chapter 17: Genes involved in pharmacoresistant epilepsy -- Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders -- Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery -- Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses -- Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility -- Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy -- Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy -- Chapter 24: Vagus Nerve Stimulation for Intractable Seizures -- Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy -- Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.

Description / Table of Contents: Chapter 1. Pandemic-Era Digital Education: Insights from an Undergraduate Medical Programme -- Chapter 2. Use of Lt Systems in Large Class Lab Delivery -- Chapter 3. COVID-19 Adaptations for Biomedical Teaching and Assessment Within the Undergraduate Dental Curriculum -- Chapter 4. One Size Does Not Fit All in Remote Anatomy Teaching -- Chapter 5. From Lecture Halls to Zoom Links: How Can Educational Theory Help Us to Deliver Effective and Engaging Teaching in an Online Environment? -- Chapter 6. Collaborative, Two-Directional Live Streaming to Deliver Hands-on Dissection Experience during the COVID-19 Lockdown -- Chapter 7. Livestreaming Can Augment the Observation of Veterinary Post-mortem Examinations -- Chapter 8. Virtual Reality for Anatomy and Surgical Teaching -- Chapter 9. Can Synchronous Online Near-Peer Teaching Offer the Same Benefits as the Face-to-Face Version When Used in Clinical Neuroanatomy Education? -- Chapter 10. COVID-19 Adaptations with Virtual Microscopy -- Chapter 11. The Challenges of Visualisation During Delivery and Assessment of Clinical Teaching Under COVID-19: A Reflective Account of Problem Solving -- Chapter 12. Not for Room 101.

Description / Table of Contents: Chapter 1. Magnetic Field Parameters and Biological Sample Differences that Lead to Differential Bioeffects -- Chapter 2. Static Magnetic Field Direction-induced Differential Biological Effects -- Chapter 3. Magnetic Properties of Biological Samples -- Chapter 4. Molecular Mechanisms for Electromagnetic Field Biosensing -- Chapter 5. Controlling Cell Membrane Potential with Static Non-uniform Magnetic Fields -- Chapter 6. Impact of Static Magnetic Fields on Cells -- Chapter 7. Impact of Static Magnetic Fields on Microorganisms, Plants and Animals -- Chapter 8. Static Magnetic Fields on Human Bodies -- Chapter 9. Potential Applications of Static Magnetic Fields in Cancer Treatment -- Chapter 10. Effects of Static Magnetic Fields on Diabetes and Its Complications -- Chapter 11. Impacts of Static Magnetic Field on Bone Health -- Chapter 12. Effects of Static Magnetic Fields on the Immune System -- Chapter 13. Biological Effects of Static Magnetic Fields on the Nervous System -- Chapter 14. The Biological Effects of Long-term Static Magnetic Field Exposure -- Chapter 15. Prospects, Pitfalls, and Opportunities for Human Static Magnetic Field Therapy.

Description / Table of Contents: The development of the cerebellum: from the beginnings -- Part I: Responsibilities and liabilities -- Chapter2. The embryology and anatomy of the cerebellum -- Chapter 3. Cellular and genetic programs underlying cerebellum development -- Chapter 4. Early Purkinje Cell Development and the Origins of Cerebellar Patterning. - Chapter 5. Development of the Fish Cerebellum. -Chapter 6. Cerebellar developmental disorders and cerebellar nuclei -- Chapter 7. Motor circuit abnormalities during cerebellar development -- Chapter8. Developmental disorders of the cerebellum and neurotrophic factors -- Chapter9. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development -- Chapter10. The ubiquitin proteasome system and cerebellar developmental disease -- Chapter11. Epigenetics and Cerebellar Neurodevelopmental Disorders -- Chapter12.. Hormonal regulation of cerebellar development and its disorders -- Chapter13. Infections of the Cerebellum -- Chapter14. Neuroimmune mechanisms of cerebellar development and its developmental disorders -- Chapter15. Teratogenic influences on cerebellar development -- Chapter16. Primary pediatric brain tumors of the posterior fossa -- Chapter17. Primary pediatric brain tumors of the posterior fossa -- Chapter18. Can cerebellar neurodevelopmental disorders affect behavioral disorders or vice versa -- Chapter19. Neurodevelopmental disorders of the cerebellum: autism spectrum disorder -- Chapter20. Congenital cerebellar disease -- Chapter21. Clinical features, assessment, and management of patients with developmental and other cerebellar disorders -- Chapter22. Epidemiology of cerebellar disorders -- Chapter23. Cerebellar transplantation: a potential model to study repair and development of neurons and circuits in the cerebellum. - Chapter 24. Non-coding RNAs and cerebellar development. - Chapter 25. Defining the Cerebellar Cytoarchitecture Using MRI. .

Description / Table of Contents: Chapter 1.Deciphering New Drug Targets in Alzheimer’s Disease -- Chapter 2. Novel Therapeutic Targets for Treating Alzheimer’s Disease -- Chapter 3. Modified Investigation Tools and Techniques Useful in Alzheimer’s Disease Research -- Chapter 4. Dual Specificity Tyrosine Phosphorylation Regulated Kinase1A (DYRK1A) Inhibitors: The Quest for a Disease-Modifying Treatment for Alzheimer’s Disease -- Chapter 5. β-secretase as a primary drug target of Alzheimer disease: Function, Structure, and Inhibition -- Chapter 6. Endocrine Receptors: The Potential Therapeutic Targets for Alzheimer’s -- Chapter 7. Calcium Channels as a Potential Therapeutic Target for Alzheimer’s Disease -- Chapter 8. Traversing Through the Trajectory of Pathogenic Astrocytes in Alzheimer’s Disease -- Chapter 9. Targeting Mitochondrial Dynamics as a Restorative Approach in the Treatment of Alzheimer’s Disease -- Chapter 10. Epigenetic Therapy for Alzheimer’s Disease -- Chapter 11. Exploring the Diverse Roles of GSK-3ß Kinase in Alzheimer’s Disease -- Chapter 12. Role of Target Fishing in Discovery of Novel Anti-Alzheimer’s Agents: In Silico Applications -- Chapter 13. Multi-Target Directed Ligand Approach in Anti-Alzheimer’s Drug Discovery -- Chapter 14. Investigating the Role of Tau Proteins in Alzheimer’s Disease-From Typical Functioning MAPs to Aberrant Fibrillary Deposits in the Brain -- Chapter 15. The Overview of Drugs Used in Alzheimer’s Disease and Their Molecular Targets.

Description / Table of Contents: Part I. Search for novel tumor epitopes related to carbohydrates -- Chapter 1.1. The ganglioside structures: chemistry and biochemistry -- Chapter 1.2. Fucosylated proteins as cancer biomarkers -- Part II. Assembly of glycoconjugates -- Chapter 2.1. Siglec-7 and synthetic sialylpolymer -- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis -- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer -- Part III. Signaling pathways modulated by glycosylation -- Chapter 3.1. Significance of FUT8in pancreatic cancer and others -- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells -- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules -- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells -- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction -- Part V. Clinical trials targeting glycosignals -- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.

Description / Table of Contents: 1.How Immune-inflammatory processes link neurodegenerative and psychiatric disorders -- 2.Gut-Microbiota-Brain Axis: pathophysiological mechanism in neuropsychiatric disorders -- 3.Microbiome- induced autoimmunity and novel therapeutic intervention -- 4.The key role of microlia and circulating monocytes in etipathology neuropsychiatric disorders -- 5.Neuro-immuno-epigenetics of prenatal psychological stress -- 6.C-reactive protein (CRP): a potent inflammation biomarker in psychiatric disorders -- 7.Neuroinflammation, neurognesis and neuroprotection in schizophrenia -- 8.Autoimmue psycosis: concept, clinical manifestation and management -- 9.Stress, autonomic nervous system and kynurenine pathway in major depression -- 10.Brain-gut-microbiome axis in major depression : novel therapeutic approach -- 11.Glial-Neuronal Interaction in Synapses: A Possible Mechanism of the Pathophysiology of Bipolar Disorder -- 12.Neuroimmaging of inflammation in depression and anxiety disorders -- 13.Neuroinflammation and immune-kynureinine pathway in anxiety disorders -- 14.Inflammatory-mediated responses in development of neurogeneartive diseases -- 15.The connection between gut-brain axis and PTSD -- 16.Eating disorders : Gut microbiota-immune-brain interactions -- 17.Sleep-immune crosstalk and sleep disorders -- 18.Obsessive-compulsive disorder: immuno-inflammatory disorder? -- 19.Cytokine, neuroinflammation and neurodeneration in Alzheimer’s disease -- 20.Molecular imaging of neuroinflammation in Alzheimer's disease and MCI -- 21.The role of N-Methyl-D-Aspartate Receptor Neurotransmission and mictobiota in Alzheimer’s disease -- 22.Neuroglial activation and neuroinflammation in the brain of patients with autism -- 23.Suicide and inflammation -- 24.Anti-inflammatory effect of Traditional Chinese Medicine on the concept of Mind-body interface -- 25.Anti-inflammatory therapy as a promising target in neupsychiatric disorders.

Description / Table of Contents: Tools for optogenetic probing of nociceptive pathways; Monitoring activity -- An open science model to accelerate the generation, implementation and distribution of optogenetics and viral tools -- Vagal neuroinflammation accompanying respiratory viral infection: An overview of mechanisms and possible clinical significance -- Stress-induced Visceral Analgesia: Concept and Pathways -- Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders -- EPIGENETIC REGULATION OF STRESS-INDUCED VISCERAL PAIN -- The biomechanics and mechanotransduction in visceral nociception -- VISCERAL NOCICEPTION IN GASTROINTESTINAL DISEASE -- Epithelial-Neuronal Communication in Visceral Pain -- Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome -- A fentanyl analogue that activates u-opioid receptors in acidified tissues inhibits colitis pain without opioid side effects -- Signalling in the Gut -- Translating colonic sensory afferent peripheral mechanosensitivity into the spinal cord dorsal horn -- Translating colonic afferent peripheral sensitivity into the spinal cord dorsal horn -- Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain -- Pre-clinical Models of Endometriosis -- Spinal afferent innervation of the uterus -- Post-infectious bladder hypersensitivity in the development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).

Description / Table of Contents: Part 1: Considering sex and gender in research studies -- Sex and Gender Science -- Best practices in the study of sex? -- Best practices in the study of Gender Differences -- The special case of a lack of sex differences – the naked mole rat? -- Lateralization and -- Part 2: Sex differences in cognitive and mental health across the lifespan -- Depression -- Schizophrenia -- Immune and neurodevelopmental disorders – autism? -- Social Cognition -- Cognition and cognitive ageing -- Part 3: Diseases of the brain and relevance of sex -- Epilepsy -- Stroke -- AD -- Parkinson’s -- Multiple Sclerosis.

Description / Table of Contents: Part I: Basic Science of Cerebellum and Ataxias -- Functional anatomy of the cerebellum -- Cerebellar physiology -- Cerebellar biochemistry/pharmacology -- Genetics of dominant ataxias -- Autosomal and X-linked degenerative ataxias: from genetics to promising therapeutics -- Seeking therapies for Spinocerebellar Ataxia: from gene silencing to systems-based approaches -- Ion Channel Genes and Ataxia -- Part II: Biomarkers and tools of trials -- How to Design a Therapeutic Trial in SCAs -- Therapy development for spinocerebellar ataxia: Rating Scales and Biomarkers -- Clinical rating scales for ataxia -- Scale for Ocular motor Disorders in Ataxia (SODA): Procedures and Basic Understanding -- Cerebellar learning in the prism adaptation task -- Blood and CSF biomarkers in autosomal dominant cerebellar ataxias -- Part III: Autosomal Dominant Cerebellar Ataxias -- Riluzole in progressive cerebellar ataxias -- ASOs against ATXN2 in preclinical and phase 1 trials -- Antisense oligonucleotide therapy against SCA3 -- Spinocerebellar ataxia type 7: From mechanistic pathways to therapeutic opportunities -- Experimental neurotransplantation for cerebellar ataxias -- Development of mesenchymal stem cells therapy for the treatment of polyglutamine SCA: from bench to bedside -- Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia -- Cerebellar Transcranial Magnetic Stimulation in Cerebellar Ataxias -- Physical therapy in Cerebellar Ataxia -- Part IV: Autosomal Recessive Cerebellar Ataxias -- Recent advances on therapeutic approaches for Friedreich’s Ataxia -- Therapeutic use of interferon gamma in Friedreich ataxia -- Metabolic treatments of cerebellar ataxia -- Clinical Trials in Fragile X-Associated Tremor/Ataxia Syndrome -- Part V: Sporadic Ataxias -- Therapeutic strategies in immune-mediated cerebellar ataxias -- Coenzyme Q10 in MSA -- State of the Art and History of Therapeutics in Ataxias.

Description / Table of Contents: Chapter 1: Understanding the Mechanisms of Dendritic Arbor Development: Integrated Experimental and Computational Approaches -- Chapter 2: Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive -- Chapter 3: Environmental enrichment and functional plasticity in the hippocampus, an update on the mechanisms involved -- Chapter 4: Translatable Models of Brain and Cognitive Reserve -- Chapter 5: Cognitive Reserve: A Life-Course Perspective -- Chapter 6: Neural Correlates of Brain Reserve: A Neuroimaging Perspective -- Chapter 7: Non-pharmacological Approaches Based on Mind-Body Medicine to Enhancement of Cognitive and Brain Reserve in Humans -- Chapter 8: Roles of Synaptic Plasticity in Functional Recovery After Brain Injury -- Chapter 9: Integrated Methods of Neuromodulation for Guiding Recovery Following Stroke -- Chapter 10: Resilience in Brain Networks After Stroke -- Chapter 11: Epigenetics and brain plasticity: back to function -- Chapter 12: Functional Role of Physical Exercise and Omega-3 Fatty Acids on Depression and Mood Disorders -- Chapter 13: BRAIN RECOVERY IN CHILDHOOD: THE INTERACTION BETWEEN DEVELOPMENTAL PLASTICITY AND REGENERATIVE MECHANISMS -- Chapter 14: Estrogen Neuroprotective Activity After Stroke and Spinal Cord Injury -- Chapter 15: Making Meaning of Acquired Brain Injury: Resources for Functional Recovery -- Chapter 16: An Update on Premorbid Personality Traits and Brain Recovery - Another Aspect of Resilience -- Chapter 17: Psychological Aspects of Recovery After Brain Injury: A Focus on Psychodynamic Factors -- Chapter 18: Artificial Intelligence applications for Traumatic Brain Injury research and clinical management.

Description / Table of Contents: Chapter 1. The COVID-19 Pandemic: SARS-CoV-2 Structure, Infection, Transmission, Symptomology and Variants of Concern -- Chapter 2. Long-term Vaccination and Treatment Strategies for COVID-19 Disease and Future Coronavirus Pandemics -- Chapter 3. Consequences of the Lockdown - Domestic Violence during the COVID-19 Pandemic -- Chapter 4. Psychological distress impact of Coronavirus disease (COVID-19) outbreak on three continents: A systematic review and meta-analysis -- Chapter 5. A Molecular Biomarker-based Triage Approach for Targeted Treatment of Post-COVID-19 Syndrome Patients with Persistent Neurological or Neuropsychiatric Symptoms -- Chapter 6. Genetic Associations with Coronavirus Susceptibility and Disease Severity -- Chapter 7. COVID Diagnostics: from Molecules to Omics -- Chapter 8. Assessing Biomarkers in Viral Infection -- Chapter 9. Proteomic Investigation of COVID-19 Severity During the Tsunamis Second Wave in Mumbai -- Chapter 10. NMR-Metabolomics in COVID-19 Research -- Chapter 11. Potential Biomarkers of Mitochondrial Dysfunction Associated with COVID-19 Infection -- Chapter 12. Red Cell Distribution Width as a Prognostic Indicator for Mortality and ICU Admission in Patients with COVID-19 -- Chapter 13. Predicting the COVID-19 Patients Status using Chest CT Scan Findings: A Risk Assessment Model Based on Decision Tree Analysis -- Chapter 14. Inferring Recombination Events in SARS-CoV-2 Variants In Silico -- Chapter 15. Amplicon-based Nanopore Sequencing of Patients Infected by the SARS-CoV-2 Omicron (B.1.1.529) Variant in India -- Chapter 16. Perspectives on Rapid Antigen Tests for Downstream Validation and Development of Theranostics -- Chapter 17. Machine Learning and COVID-19: Lessons from SARS-CoV-2 -- Chapter 18. The Relationship between Psoriasis, COVID-19 Infection and Vaccination during Treatment of Patients -- Chapter 19. Immunogenicity of Inactivated SARS-CoV-2 Vaccine (BBIBP-CorV; Sinopharm) and Short-term Clinical Outcomes in Vaccinated Solid Organ Transplant Recipients: A Prospective Cohort Study -- Chapter 20. Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective -- Chapter 21. Antiviral Mechanisms of Curcumin and its Derivatives in Prevention and Treatment of COVID-19: A review -- Chapter 22. Evaluation of Curcumin-Piperine Supplementation in COVID-19 Patients Admitted to the Intensive Care: A Double-Blind, Randomized Controlled Trial -- Chapter 23. Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases of COVID-19: A Hypothetical Approach -- Chapter 24. The Potential Effect of Royal Jelly on Biomarkers Related to COVID-19 Infection and Severe Progression -- Chapter 25. Statins: Beneficial Effects in Treatment of COVID-19 -- Chapter 26. Multiplex Immunoassay Approaches Using Luminex® xMAP® Technology for the Study of COVID-19 Disease -- Chapter 27. Rapid Detection of SARS-CoV-2 Variants of Concern by Genomic Surveillance Techniques.

Description / Table of Contents: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.

Description / Table of Contents: PART I: Fundamental Aspects -- Chapter 1. Definition of Tremor -- Chapter 2. Membrane Mechanisms of Tremor -- Chapter 3 Advances in the Genetics of Human Tremor -- Chapter 4. Two origins of tremors related to the Guillain-Mollaret triangle: the forward model-related tremor and the inferior olive oscillation-related tremor -- PART II:Tremor in Clinical Practice -- Chapter 5. Physiologic Tremor -- Chapter 6. Rest Tremor -- Chapter 7. Postural Tremors -- Chapter 8. Isometric Tremor -- Chapter 9. Essential Tremor and Other Forms of Kinetic Tremor -- Chapter 10. Cerebellar lesions and tremor -- Chapter 11. Orthostatic Tremor -- Chapter 12. Posttraumatic Tremor and Other Posttraumatic Movement Disorders -- Chapter 13 Tremor in Childhood -- Chapter 14. Metabolic Causes of Tremor -- Chapter 15. Drug-Induced Tremor -- Chapter 16. Tremor: The Clinical Approach to Reach the Diagnosis -- PART III: Assessment of tremor -- Chapter 17. Signal Processing -- Chapter 18. Diffusion imaging in Tremor -- Chapter 19. The role of the noradrenergic system in tremor pathogenesis -- Chapter 20. Metabolic Networks in Parkinson’s Disease -- PART IV: Therapies -- Chapter 21. Deep brain stimulation for tremor -- Chapter 22 Mechatronic Devices for Upper Limb Tremor.

Description / Table of Contents: Microplastic research publications from 1991 to 2020 -- Characterization and toxicology of microplastics in soils, water and air -- Coral feeding behavior on microplastics -- Microplastics remediation in the aqueous environment -- Removal of environmental microplastics by advanced oxidation processes -- Techniques for removal and degradation of microplastics -- Occurrence and removal of microplastics in wastewater treatment plants -- Microplastic souces, transport, exposure, analysis and removal -- Airborne microplastics in outdoor and indoor environments -- Nanoplastic sources, characterization, ecological impact, remediation and policies -- Microplastics in soil-plant systems.

Description / Table of Contents: Module 1_Introduction to Forensic Science & Crime -- Module 2_Criminalistics -- Module 3_ Forensic Biological Sciences -- Module 4_Forensic Physical Sciences -- Module 5_Forensic Chemical Sciences -- Module 6_Emerging fields in Trends in Forensics.

Description / Table of Contents: Chapter 1: Introduction: What are dendritic spines? -- Chapter 2: Techniques to render dendritic spines visible in the microscope -- Chapter 3: Electrophysiology of dendritic spines: information processing, dynamic compartmentalization and synaptic plasticity -- Chapter 4: Dendritic spines, synaptogenesis and synaptic pruning for the developmental organization of brain circuits -- Chapter 5: Neurotrophic factors and dendritic spines -- Chapter 6: Glial cell modulation of dendritic spine structure and synaptic function -- Chapter 7: Dendritic spines in learning and memory: from first discoveries to current insights -- Chapter 8: Steroid hormone interaction with dendritic spines: implications for neuropsychiatric disease -- Chapter 9: Morphological features of human dendritic spines.

Description / Table of Contents: Preface -- PART 1: To fear or not -- Disambiguating fear as an emotional state vs. threat detection. Molecular and Neural circuits of fear extinction. Psychological and theoretical elements on the concept of fear extinction. Neural circuit of fear extinction: psychophysiology -- PART 2: Individual differences in fear extinction -- The impact of sex differences and sex hormones on fear extinction. Impact of sleep on fear extinction. Impact of stress and exercise on fear extinction. Intersect between the intrinsic and extrinsic factors that modulate fear extinction -- PART 3: Psychopathology -- Fear extinction and its relevance to psychopathology. Developmental fear and its extinction imaging. Fear extinction and adult psychopathology -- Part 4: Therapeutics and neuromodulations of fear extinction -- Exposure therapy and other behavioral therapeutics targeting fear extinction circuits. Novel pharmacotherapeutics targeting fear extinction circuits. Reconsolidation and its link and impact on fear extinction. Technological advances in exposure therapy: virtual and augmented reality. Novel approaches using neurostimulation targeting fear extinction.

Description / Table of Contents: Chapter 1. The Importance of Integrating the Visual Arts into the Medical Curriculum -- Chapter 2. Using Medical Illustration to Improve Understanding of Endometriosis -- Chapter 3. Editorial Medical and Scientific Illustration -- Chapter 4. Current Approaches in Narrative Medical Visualization -- Chapter 5. Animation for Science Communication: A Description of the Production Process and Contexts for Using Science Animation -- Chapter 6. Effect of the Rings: A Visual Story Design Comparing Three Chemical Characters -- Chapter 7. Diabetes Year One, Random Fluctuations and Mental Goblins: Auto-Ethnographic Pathographies and Medical Comics -- Chapter 8. Playing with Science: Games as a Medium of Science Communication -- Chapter 9. Increasing Microbiology Literacy about the Public Health Threat of Antimicrobial Resistance Through Art-Science Interactions -- Chapter 10. Collaged Creatures: Using Collage Art Practice and Posthuman Ethics to Discuss Bioengineering Hybrids.

Description / Table of Contents: Chapter 1. An Introduction to Scaffolds, Biomaterial Surfaces, and Stem Cells -- Part I. Structural Scaffolds and Bio-activation -- Chapter 2. Polymeric and Biomimetic ECM Scaffolds for Tissue Engineering Applications -- Chapter 3. Versatile Hydrogels in Regenerative Medicine -- Chapter 4. Multilayer Microcapsules with Tailored Structures and Properties as Delivery Carriers for Drugs and Growth Factors -- Part II Biomaterials Surfaces/Interfaces and Bio-interactions. Chapter 5. Interactions of Biomaterial Surfaces with Proteins and Cells -- Chapter 6. Surface Modification of Tissue Engineering Scaffolds -- Chapter 7. Gradient Biomaterials and Their Impact on Cell Migration -- Chapter 8. Stem Cell Differentiation Mediated by Biomaterials/Surfaces -- Part III Regeneration of Some Clinic-Targeted Tissues -- Chapter 9. Cartilage Regeneration -- Chapter 10. Skin Regeneration -- Chapter 11. Regeneration of Blood Vessels -- Chapter 12. Cardiac repair and regeneration -- Chapter 13. Nerve Regeneration.

Description / Table of Contents: 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection.

Description / Table of Contents: Part 1: Setting the scene -- Chapter 1: Life after Academia: Launching your Pharma/Biotech Career -- Chapter 2: Competences for Pharmacists -- Chapter 3: Job and Career Opportunities in the Pharmaceutical Industry: An Overview -- Part 2: Opportunities along the drug/product life cycle -- Chapter 4: Career Opportunities in Toxicology -- Chapter 5: Job Possibilities in Clinical Research -- Chapter 6: How to Get and Develop a Career in a Market Access Role in the Medical Devices Industry -- Chapter 7: Job Opportunities in Pharmaceutical Marketing -- Chapter 8: Working in Medical Affairs and Clinical Operations: Life-Changing Careers -- Chapter 9: The Role of Medical Science Liaison -- Chapter 10: Career Development for Physicians in the Biopharmaceutical Industry -- Part 3: Opportunities in Supportive Functions -- Chapter 11: Job and Career Opportunities in Regulatory Affairs/Science -- Chapter 12: Job Opportunities in Clinical Research Quality Assurance -- Chapter 13: Job Opportunities in Quality Assurance Related to Manufacturing of Medicinal Products -- Part 4: Other Opportunities in the Pharmaceutical and Biomedical Sector -- Chapter 14: Careers Perspective in a Science and Technology Park -- Chapter 15: To be or not to be: Entrepreneurship and Enterprise Creation as a Way to Innovate in Life Sciences -- Chapter 16: How to Become a Successful Hospital and Community Pharmacist -- Part 5: Practical tips and tricks -- Chapter 17: A Successful Career in the Life Sciences Industry: How to Write your Strongest Resumé and Ace that Interview -- Chapter 18: Skill Building for Career Advancement: Public Speaking and Networking -- Chapter 19: Training Opportunities for a Career in the Pharmaceutical and Biomedical Industry/Sector.

Description / Table of Contents: 1. Introduction on Tuberculosis: Integrated Studies for a Complex Disease -- 2. Global Tuberculosis Epidemiology -- 3. Heterogeneity in Tuberculosis -- 4. The Unequivocal Relationship between Tuberculosis and Tobacco: Integration of Two Maladies -- 5. Relationship between Pre-existing Cancer and Tuberculosis -- 6. Laboratory Diagnosis of Tuberculosis -- 7. The Role of Diagnostic Microdevices in the Fight Against Tuberculosis -- 8. Immunodiagnostics of Tuberculosis: Recent Discoveries -- 9. Role of Bronchoscopy in Diagnostics and Treatment of Tuberculosis -- 10. Diagnosis of Childhood Tuberculosis in Low- and Middle-income Countries -- 11. Pediatric Tuberculosis: Current Evidence for Laboratory Diagnosis -- 12. A Multidisciplinary Approach Towards Finding and Treating All Tuberculosis Patients -- 13. Chemotherapy for Drug-Susceptible Tuberculosis -- 14. The Pharmacokinetic and Pharmacodynamic Properties of Antitubercular Medications -- 15. Immune Approaches In Tuberculosis Treatment -- 16. Inhalation Therapy in Pulmonary Tuberculosis -- 17. Role of Micronutrients in Tuberculosis Management -- 18. Drug Resistance in Tuberculosis: Mechanisms, Diagnosis, New Responses, and the Need for An Integrated Approach -- 19. Resistance in Tuberculosis: Molecular Mechanisms and Modulation -- 20. Personalized Tuberculosis Care for Drug-Resistant Tuberculosis -- 21. Important Targets and Inhibitors of Mycobacterium Tuberculosis -- 22. P-type ATPases: A Relevant Component in Mycobacterium tuberculosis Viability -- 23. The Challenges of Antitubercular Drug Discovery -- 24. Exploring Decaprenylphosphoryl-β-D-ribose 2’-Epimerase 1 (DprE1): A Target for Anti-Tubercular Drugs -- 25. Energy Pathways in Mycobacterium Tuberculosis -- 26. Drug Discovery for Non-Tuberculous Mycobacteria: Recent Updates -- 27. Challenges for Contact Tracing and Tuberculosis Preventive Therapy Scale-up -- 28. Exploring Problematizations Underlying Tuberculosis Control Strategies: A Cross-Country Analysis of India and Kenya -- 29. Challenges in Prevention and Management of Tuberculosis -- 30. Tuberculosis in Contacts and Healthcare Workers -- 31. Tuberculosis Among People Who Use Drugs: Multilevel Considerations for Prevention, Diagnosis, and Treatment -- 32. Anti-Tumor Necrosis Factor-α Antagonists and Tuberculosis -- 33. Breast Tuberculosis -- 34. Central Nervous System Tuberculosis: Pathogenesis, Diagnosis, and Management -- 35. Pleural Tuberculosis -- 36. Ocular Tuberculosis -- 37. Ocular Tuberculosis: Biomarkers for Risk Stratification -- 38. Bone and Joint Tuberculosis -- 39. Abdominal Tuberculosis: Pathogenesis, Clinical Features, and Diagnosis -- 40. Bovine Tuberculosis at The Interface of Cattle, Wildlife, and Humans -- 41. Evolution and Molecular Characteristics of Mycobacterium Tuberculosis and Mycobacterium Bovis -- 42. Animal Tuberculosis: Gross Lesions and Anatomopathological Diagnosis -- 43. Estimation of Microbial Mutation Rates in Tuberculosis Research -- 44. The Role of Epigenetics in the Development of Anti-Tuberculosis Drug Resistance -- 45. Multiomics Integration of Tuberculosis Pathogenesis -- 46. Lung Microbiome in Tuberculosis -- 47. The Correlation of Microbiota and Host Epigenome in Tuberculosis -- 48. The Pathogenesis and Progression of Sarcoidosis from The Standpoint of Tuberculosis -- 49. Tuberculosis: A Historical and Global Bioethical Perspective -- 50. The Problem of Tuberculosis: Myths, Stigma, and Mimics -- 51. Tuberculosis: Integrated Studies for a Complex Disease 2050.

Description / Table of Contents: Sensory Regeneration in the Inner Ear: History, Strategies and Prospects -- Non-mammalian Hair Cell Regeneration: Cellular Mechanisms of Morphological and Functional Recovery -- Cell Junctions and the Mechanics of Hair Cell Regeneration -- Mammalian Hair Cell Regeneration -- Specification and Plasticity of Mammalian Cochlear Hair Cell Progenitors -- Inner Ear Cells from Stem Cells – a Path Towards Inner Ear Cell Regeneration -- Spiral ganglion neuron regeneration in the cochlea: regeneration of synapses, axons and cells -- Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear.

Description / Table of Contents: Introduction on Integrated Science of Global Epidemics -- Emerging Viral Infections in Human Population -- One Health as An Integrated Approach: Perspectives from Public Services for Mitigation of Future Epidemics -- Multipronged Approach to Combat COVID-19: Lessons from Previous Pandemics for the Future -- Response to Disease Outbreaks in Africa: A Call to Build Resilient Health Systems -- Navigating Global Public Influenza Surveillance Systems for Reliable Forecasting -- Three Respiratory Syndrome Epidemics (SARS, MERS, COVID-19) in Two Decades: Clinical Epidemiological Considerations -- Epidemic in Complex Networks and Some Ideas About the Impact of Isolation Strategies in the Context of the COVID-19 Pandemic -- Optimal Control: Application and Applicability in Times of Pandemics -- Analysis of A COVID-19 Model Implementing SocialDistancing as An Optimal Control Strategy -- Impact of Policy Implementations on the Propagation of COVID-19 Before Vaccine -- Environmental Factors Associated with Global Pandemic Transmission and Morbidity -- Urbanization and the Epidemiology of Infectious Diseases: Towards the Social Framing of Global Responses -- Pandemics and Mass Casualties: Cornerstones of Management -- Social Marketing Contributions to Mitigate Global Epidemics -- The Significance of Super Intelligence of Artificial Intelligence Agencies in the Social Savageries of COVID-19: An Appraisal -- Integration of Sex and Gender Approaches in National Ethics Committees’ Mandate to Appraise COVID-19 Research Protocols: Lessons from West Africa -- Psychology, Law, Ethics, Telehealth, and the Global Pandemic -- Physical Inactivity, Sedentarism, and Low Fitness: A Worldwide Pandemic for Public Health -- The Global Epidemic of Diabesity: Are We Heading for An Unsustainable Future? -- Nutrition, Function, and Quality of Life in Older Adults Socially Isolated Due to the COVID-19 Pandemic: A Focus on Telehealth Interventions -- Africa’s Response to Pandemics -- Vaccine Hesitancy and Refusal: History, Causes, Mitigation Strategies -- Vaccine Compliance versus Trust in a Pandemic -- Child Development in A Crisis: A Pandemic -- HIV/AIDS Problems and Policies in Adolescent Population -- Addressing Needs of Foreign Schoolchildren to Combat a Global Epidemic of Dengue Virus Infection: Transnational and Trans-sectoral Initiatives -- Integrated Science of Global Epidemics 2050.

Description / Table of Contents: Chapter 1. Introduction to neurogenetics -- Chapter 2. Neurogenetic analysis in Caenorhabditis elegans -- Chapter 3. Regionalisation of the early nervous system -- Chapter 4. Early neurogenesis and gliogenesis in Drosophila -- Chapter 5. Neural stem cells and brain tumour models in Drosophila -- Chapter 6. Eye development in Drosophila: from photoreceptor specification to terminal differentiation -- Chapter 7. Neurogenetics of memory, learning and forgetting -- Chapter 8. Evolution and origins of nervous systems -- Chapter 9. Neural stem and progenitor cells in the mammalian brain -- Chapter 10. Models of neurodegenerative diseases.

Description / Table of Contents: Section I: Understanding Grant Writing: What is your Aim (Ambition-Interest-Mission), and what you want to do -- What is a grant? How to prepare for writing a grant proposal application -- Funders Perspective: What the funding body expects from researchers? -- Funding organizations for science and healthcare -- Obtaining letters of support -- Section II: The process for grant writing: Writing a Grant Proposal for a Single Centre Study: step-by-step approach -- Budgeting the project-detailing the required funding and expenditure -- Proving the competency of the researcher and the adequacy of the infrastructure to carry out the research -- Agreement and MOU – ethical and legal aspects of funding for healthcare research -- Write an impressive cover page (Covering letter) and abstract for the grant proposal application -- Surveillance plan and site visit – Roles and rights of the researcher and the funding agency -- Sources of funding and acknowledgment – Good Clinical Practice Guidelines -- Writing a grant proposal for a Collaborative study -- Checklist for grant proposal – Mandatory elements -- Tips for improvising the chance of getting the grant -- Dealing with The Rejected Grant Proposal- Learning From The Mistakes -- Section III: Grant writing for specific regional funding organizations: Preparing a grant proposal for medical research in the UK -- Preparing a grant proposal for the USA -- Preparing a Grant Proposal for Australia -- Proposal Writing for Grant Application in Malaysia -- Grant writing for other Asian countries.

Description / Table of Contents: Part I. Concepts -- Chapter 1. A History of Immune and Neuroendocrine System Interactions -- Chapter 2. Philosophical Perspectives on Neuroendocrine-Immune Interactions: The Building Block Model and Complementary Neuro-Endocrine-Immune-Microbiota Systems Approaches -- Chapter 3. The Behavioural Immune System of Lower Vertebrates -- Part II. Regulatory Pathways -- Chapter 4. Cytokines and Hypothalamo-Pituitary-Adrenal Axis Activation: Now a Classic of Immune-Neuroendocrine System Interactions -- Chapter 5. Catecholamines and Immunomodulation -- Chapter 6. Neuroendocrine-immune Interactions in Major Depressive Disorder: Glucocorticoids and Glucocorticoid Receptors -- Chapter 7. Brain Fluids, Blood-Brain Interfaces, and Their Involvement in Neuroimmune Regulation During Development and in Adulthood -- Chapter 8. Neuropeptide Binding Autoantibodies Regulating Neuroendocrine Communications -- Part III. Modulation -- Chapter 9. Postnatal Development of Neuroimmune Responses -- Chapter 10. Sex Differences in Neuroendocrine-Immune Interactions -- Chapter 11. Biological Clocks and Immune Function -- Chapter 12. Influence of the Gut Microbiota on Neuroendocrine-Immune Interactions -- Part IV. Disease -- Chapter 13. Energy Balance and Neuroendocrine-Immune Regulation in Chronic Inflammatory and Neoplastic Diseases: An Evolutionary Perspective -- Chapter 14. Autonomic, Immune, Metabolic and Neuroendocrine Dimensions of Anorexia Nervosa: An Integrative View.

Description / Table of Contents: A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.

Description / Table of Contents: Chapter 1 Overview of the relationship between aluminum exposure and health of human being.-Chapter 2 The Chemistry of Human Exposure to Aluminum -- Chapter 3 Entry and Deposit of Aluminum in Brain -- Chapter 4 Aluminum as a CNS and immune system toxin across the life span.-Chapter 5 Occupational exposure to aluminum and cognitive impairment -- Chapter 6 Debated relationship between Exposure to Aluminum in Daily Life and Alzheimer’s Disease -- Chapter 7 Animal Model of Aluminum-Induced Alzheimer’s like Disease -- Chapter 8 Aluminum-induced AD-like Pathological Features.-Chapter 9 Aluminum induced neural cells death -- Chapter 10 Aluminum-Induced Electrophysiological Variation, Synaptic Plasticity Impairment, and Related Mechanism.-Chapter 11 Cross Talk Between Aluminum and Genetic Susceptibility -- Chapter 12 Epigenetic modification in aluminum-induced neuron death and synaptic impairment -- Chapter 13 Neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) -- Chapter 14 Alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects.

Description / Table of Contents: Chapter 1. Malignant Glioma -- Chapter 2. Benign Glioma -- Chapter3. Meningioma and Other Meningeal Tumors -- Chapter4. Epondymomas in Pediatric and Adults -- Chapter5. Medulloblastomas in Pediatric and Adults -- Chapter6. Benign and Malignant Tumors of The Pineal Region -- Chapter7. The Tumors of Choroid Plexus and Other Ventricular Tumors -- Chapter8. Embryonal Tumors of The Central Nervous System with Multilayered Rosettes and Atypical Teratoid/Rhabdoid Tumors -- Chapter9. Glioneuronal and Neuronal Tumors of the Central Nervous System -- Chapter10. Benign and Malignant Tumors of the Pituitary Gland -- Chapter11. Craniopharyngioma in Pediatric and Adults -- Chapter12. Schwannomas of Brain and Spinal Cord -- Chapter13. Other Nerve-Sheet Tumors of Brain and Spinal Cord -- Chapter14. Hemangioblastomas and Other Vascular Originating Tumors of Brain or Spinal Cord -- Chapter15. Brain and Spinal Cord Tumors of Embryonic Origin -- Chapter16. Brain and Spinal Tumors Originating from the Germ Line Cells -- Chapter17. Benign Brain and Spinal Tumors Originating from Bone or Cartilage -- Chapter18. Benign Spinal Tumors -- Chapter19. Other Less Prevalent Tumors of the Central Nervous System -- Chapter20. Brain and/or Spinal Cord Tumors Accompanied with Other Diseases or Syndromes -- Chapter21. Psychological and Psychiatric Aspects of Brain and Spinal Cord Tumors -- Chapter22. A Brief Explanation on Surgical Approaches for Treatment of Different Brain Tumors.

Description / Table of Contents: Chapter 1. Editorial: Biosystems -- 2. Potential of Biotechnology in cancer management -- 3. Biosimilars: Promising and Rapidly Emerging Biotherapeutics -- 4. Applications of Nanomaterials in Medicine: Current status and future scope -- 5. Biomedical Applications of Nanofluids in Drug Delivery.

Description / Table of Contents: MATRICS – an update -- Cognitive [Computational] Neuroscience Test Reliability and Clinical Applications for Serious mental illness (CNTRaCS) Consortium: Progress and Future Directions -- Attention in Schizophrenia -- Perceptual Functioning -- Episodic Memory and Schizophrenia: From Characterization of Relational Memory Impairments to Neuroimaging Biomarkers -- Working Memory in People with Schizophrenia -- "Targeting Frontal Gamma Activity with Neurofeedback to Improve Working Memory in Schizophrenia" -- Cognitive Dysfunction as a Risk Factor for Psychosis -- Environmental Risk Factors and Cognitive Outcomes in Psychosis: Pre-, Perinatal, and Early Life Adversity -- Developmental manipulation-induced changes in cognitive functioning -- Genetic underpinnings of cognitive dysfunction in schizophrenia -- Primate models of cognitive deficit re schizophrenia -- Olfactory cognitive deficits -- Medication/Anticholinergic burden impacting cognition in schizophrenia An Update on Treatment of Cognitive Impairment Associated with Schizophrenia -- Cannabis & cognition -- Sex/gender differences -- Neuroinflammation linked to cognition.

Description / Table of Contents: Molecular Biomarkers.Somatic instability/Telomeres,- Genetic modifiers -- Current clinical trial biomarkers.-Pharmacodynamic biomarkers for Htt-lowering therapeutics.-Inflammatory biomarkers.-Sleep dysregulation markers.-Mitochondrial/Oxidative stress biomarkers.-Microbiomics -- Metabolomics.-Proteomics.-Transcriptomics.-Lipidomics.-Imaging marker overview.-Retinal imaging biomarkers -- MRI - non-invasive functional MRI measures -- The evolution of clinical trial methodology.-Digital biomarkers -- The future of telehealth -- Summary and future trends.

Description / Table of Contents: Part 1 General considerations -- Human iPS for clinical applications and cellular products -- 3D-printed iPS disease models -- Part 2 CNS iPSC and organoids -- iPS-derived neurons and brain organoids from patients (brain) -- iPS-derived RGCs (eye) -- iPS-derived glia (brain) -- iPSC to model blood-brain barrier endothelial cells -- Part 3 iPSC-derived nociceptive neurons -- IPSC-based peripheral nerve modeling -- Part 4 Non-neuronal specialized cell types -- iPSC-based drug screening of differentiated cardiomyocyte subtypes -- iPSC-based cardiac disease modeling: from cell to tissue -- iPSC-derived corneal endothelial cell -- iPSC-derived trabecular meshwork (eye) -- iPSC for in vitro disease modeling of diabetes.

Description / Table of Contents: 1. The human genome and its variations -- 2. Gene expression and chromatin -- 3. The basal transcriptional machinery -- 4. Transcription factors and signal transduction -- 5. A key transcription factor family: Nuclear receptors -- 6. DNA methylation -- 7. Histone modifications -- 8. Chromatin remodeling and organization -- 9. Regulatory impact of non-coding RNA -- 10. Genome-wide principles of gene regulation -- 11. Epigenetics in development -- 12. Epigenetics and aging -- 13. Epigenetics and disease -- 14. Cells and tissues of the immune system -- 15. Innate immunity and inflammation -- 16. Adaptive immunity and antigen receptor diversity -- 17. B cell immunity: BCRs, antibodies and their effector functions -- 18. Antigen-presenting cells and MHCs -- 19. T cell immunity: TCRs and their effector functions -- 20. Immunity to bacterial pathogens and the microbiome -- 21. Immunity to viral pathogens and the virome -- 22. Tolerance and transplantation immunology -- 23. Immunological hypersensitivities: Allergy and autoimmunity -- 24. Introduction to cancer -- 25. Oncogenes, signal transduction and the hallmarks of cancer -- 26 Tumor suppressor genes and cell fate control -- 27. Multistep tumorigenesis and genome instability -- 28. Cancer genomics -- 29. Cancer epigenomics.-30. Aging and cancer -- 31. Tumor microenvironment -- 32 Metastasis and cachexia -- 33. Cancer immunology -- 34 Architecture of cancer therapies -- 35 Nutrition and common diseases -- 36 Interference of the human genome with nutrients -- 37. Nutritional epigenetics, signaling and aging -- 38. Chronic inflammation and metabolic stress -- 39. Obesity -- 40. Insulin resistance and diabetes -- 41. Heart disease and the metabolic syndrome -- 42 Epigenetics, inflammation and disease.

Description / Table of Contents: Part 1 Geospatial technologies -- The effect of an open educational resource (OER) on student teachers‘ abilities to diagnose students‘ written argumentation skills -- Development of the Online Geospatial Problem-Solving Instrument: Investigating Elementary Students’ perceptual processes in geospatial problem-solving. -- A Spatial Knowledge Infrastructure for the Aegean Archipelago -- A Virtual Window to the World: Using Story Maps for SDG Visibility and Environmental Educatio -- Education for sustainable water consumption in multinational collaboration teachers training: Goals and Challenges -- Connecting Literature and Web Maps: Hungarian writers and poets online -- Part 2: Education, Geography and new Geospatial technologies and tools -- Teaching Geography with a Web GIS Approach -- Education for Sustainability Using Cloud-based Geographic Information Systems at University -- Comparative Dimensions of teaching Geography & History in Austria and in Israel, Migration of Vienna Jewry during the 1930s -- Geographiic Education for the Promotion of Spatial Citizenship: Collaborrative Mapping for Learning About the Local Environment in a Global Context -- Part 3: COVID-19 and post-COVID -19 -- The Art of Geographical Analysis of Covid-19 Related Data -- Development of a Synthetic Index of Social Vulnerability to Covid-19 in the City of Zaragoza (Spain) -- Students’ Satisfaction with Synchronous Online Learning in Times of COVID-19: A Case Study of Greek Geography Students -- Can Climate Crisis Go Viral? A Review of Climate Change Communication Lessons in the Aftermath of the COVID-19 Pandemic -- Towards a EU’s Sustainable and Humane Border Regime -- Part 4: Gepspatial technologies and application in agriculture -- Pest Management with Precision Farming Tools: the Case of the Olive Fly (Bactrocera Oleae) -- Sustainable Networking Solutions in Remote IoT Environments: Use Cases, Challenges and Solutions for Smart Agriculture.

Description / Table of Contents: Chapter 1-Land use and land cover change: advancing with geographic information science -- Chapter 2-Land use in Ontario: challenges in land use classification -- Chapter 3-The golden horseshoe: land use from past to present -- Chapter 4-First nations reserves in Ontario: effects of urban sprawl -- Chapter 5-Archaeological heritage and urban sprawl: corridors of change -- Chapter 6-The cityscape: urban growth in Toronto -- Chapter 7-Land use and health perception -- Chapter 8-Environmental injustice in southern Ontario -- Chapter 9-Happiness and land use. .

Description / Table of Contents: Cramped spaces, w(r)iggle room and everyday politics: An introduction -- Part 1: Everyday geographies of scholar activism -- Should I stay or should I go? Academic tempered radicalism in the era of ecological crisis -- Towards ‘minor’ methodologies or crisis as method -- Part 2: Repertoires of research methodologies and fieldwork experiences -- The sympoietic orchard: Everyday ways of co-creating an orchard -- Researching urban coworking spaces: Everyday life and reflexivity during the fieldwork -- Beyond the club: A feminist poetic inquiry to reimagine festive spaces and practices of the electronic scene in Paris -- Mapping sifikile – A place of home: Methodological reflections on hope from a coal frontier -- Madame Ruetabaga’s prefigurative politics at the urban fringes of Grenoble -- Digital practices on social media: New perspectives on the production of space and geopolitical inquiry -- Part 3: Embodied negotiations: Agency, survival, care -- Life at the margins: Women’s everyday practices as resistance in a working-class neighbourhood in Barcelona -- Digitalisation of working space: Women working from home in Turkey -- Home, work and everyday life: Gender dynamics in a mining city -- Epilogue.

Description / Table of Contents: Chapter1. Introduction -- PartI. Mapping for the Goals on Poverty, Hunger, Health, Education, Gender, Water, and Energy -- Chapter2. Open Data Addressing Challenges Associated with Informal Settlements in the Global South -- Chapter3. Leveraging Spatial Technology for Agricultural Intensification to Address Hunger in Ghana -- Chapter4. Rural Household Food Insecurity and Child Malnutrition in Northern Ghana -- Chapter5. Where is the Closest Health Clinic? YouthMappers map their communities before and during the COVID-19 pandemic -- Chapter6. Cross-continental YouthMappers Action to Fight Schistosomiasis Transmission in Senegal -- Chapter7. Understanding YouthMappers Contributions to Building Resilient Communities in Asia -- Chapter8. Activating Education for Sustainable Development Goals through YouthMappers -- Chapter9. Seeing the World Through Maps: An Inclusive and Youth Oriented Approach -- Chapter10. Youth Engagement and the Water-Energy-Land Nexus in Costa Rica -- Chapter11. Power Grid Mapping in West Africa -- Chapter12. Mapping Access to Electricity in Urban and Rural Nigeria -- PartII. Youth Action on Work, Leadership, Innovation, Inequality, Cities, Production and Land -- Chapter13. Stories from Students Building Sustainability Through Transfer of Leadership -- Chapter14. Drones For Good: Mapping Out the SDGs Using Innovative Technology in Malawi -- Chapter15. Assessing YouthMappers Contributions to the Generation of Open Geospatial Data in Africa -- Chapter16. Mapping Invisible and Inaccessible Areas of Brazilian Cities to Reduce Inequalities -- Chapter17. Visualizing YouthMappers Contributions to Environmental Resilience in Latin America -- PartIII. Marking a Path to Goals on Sustainable Communities, Consumption, Climate, Oceans, Land, and Justice -- Chapter18. Youth Engagement and Participation in Mitigating Perennial Flooding in Kampala, Uganda using Open Geospatial Data -- Chapter19. Sustainable Mobility through Knowledge Exchange and Collaborative Mapping of Cycling Infrastructure: SIGenBici in Medellín, Colombia -- Chapter20. Wastesites.io: Mapping Solid Waste to Meet Sustainable Development Goals -- Chapter21. Mapping for Resilience: Extreme Heat Deaths and Mobile Homes in Arizona -- Chapter22. Mapping for Women’s Evacuation Plans during Climate-induced Disasters -- Chapter23. Sustainable Development in Oceania and the Role of Mapping for Women -- Chapter24. Sustainable Coastal Communities in the Anthropocene: Lessons from Crowd-Mapping Projects in Colombia -- Chapter25. Collaborative Cartography Making Riparian Communities Visible in Tefé, Amazonas, Brazil -- Chapter26. Open Mapping with Official Cartographies in the Americas -- Chapter27. Cities of the Future Need to be Both Smart and Just: How We Think Open Mapping Can Help -- PartIV. Supporting YouthMappers to Advance the SDGs through Institutions and Partnerships -- Chapter28. Mentoring Experiences in YouthMappers Chapters -- Chapter29. The Ecosystem Where YouthMappers Live and Thrive -- Chapter30. A Free and Open Map of the Entire World: Opportunities for YouthMappers within the Unusual Partnership Model of OpenStreetMap -- Chapter31. Youth and Humanitarian Action: Open Mapping Partnerships for Disaster Response and the SDGs -- PartV. The Paths Ahead -- Chapter32. Generation 2030: The Strategic Imperative of Youth Civic and Political Engagement -- Chapter33. Reflecting on the YouthMappers Movement.

Description / Table of Contents: Part I. The Green City: General Concept -- Chapter 1. What Does “The Green City” Mean?(Jürgen Breuste) -- Chapter 2. What Is Urban Nature? (Jürgen Breuste) -- Chapter 3. What is Urban Green and Blue Infrastructure? (Jürgen Breuste) -- Chapter 4. The Green City: General Concept (Jürgen Breuste) -- Part II. The Nature Concept – of What Urban Green Nature Consists of Part Front Matter -- Chapter 5. The Four Urban Natures Approach (Jürgen Breuste) -- Chapter 6. Urban Woodlands - Remnants of Pristine Landscape (Jürgen Breuste) -- Chapter 7. Public Urban Parks - Designed Urban Green Spaces (Jürgen Breuste) -- Chapter 8. Urban Gardens – The Private Urban Green (Jürgen Breuste) -- Chapter 9. Urban Waters – The Urban Blue Infrastructure (Jürgen Breuste) -- Chapter 10. New Urban Wildernesses - Novel Urban Ecosystems (Jürgen Breuste).

Description / Table of Contents: Chaptre 1. Brain and Spinal Cord Tumors Among the Life-Threatening Health Problems: An Introduction -- Chaptre 2. Epidemiology of Brain and Spinal Cord Tumors -- Chaptre 3. The Role of Neuro-inflammation and Innate Immunity in Pathophysiology of Brain and Spinal Cord Tumors -- Chaptre 4. The Role of Cellular Immunity and Adaptive Immunity in Pathophysiology of Brain and Spinal Cord Tumors -- Chaptre 5. Immunotherapy as a New Therapeutic Approach for Brain and Spinal Cord Tumors -- Chaptre 6. Cell of Origin of Brain and Spinal Cord Tumors -- Chaptre 7. The Role of Bioinformatics and Imaging Models in Tumorigenesis and Treatment Response of Brain and Spinal Cord Neoplasms -- Chaptre 8. The Role of Epigenetics in Brain and Spinal Cord Tumors -- Chaptre 9. Stem Cells and Targeted Gene Therapy in Brain and Spinal Cord Tumors -- Chaptre 10. Nutrition and Diet: A Double-Edged Sword in Development and Treatment of Brain Tumors -- Chaptre 11. The Role of Nanotechnology in Brain Tumors -- Chaptre 12. The Role of Nanotechnology in Spinal Cord Tumors -- Chaptre 13. The Economic Burden of Malignant Brain Tumors.

Description / Table of Contents: 1. Understanding schizophrenia: introductory aspect of the mental disorder from various perspectives -- 2. Genetic mutations and Alternative splicing in schizophrenia -- 3. Understanding the Chemical Interactions in the Brain of Schizophrenia Patients -- 4. A diagnostic perspective of schizophrenia: from past to present -- 5. Is it schizophrenia or not? - Different Biological characterization -- 6. A neurobiological aspect of schizophrenia and the relationship between neurological disorders: depression, anxiety, epilepsy -- 7. Clinical treatment available for schizophrenia -- 8. Insights into the neuro-pharmacological treatment of schizophrenia: past, present, and future -- 9. Managing Schizophrenia – A Challenge for Physicians -- 10. Pharmacotherapy and Emerging Treatment Strategies for Schizophrenia -- 11. Alternative Therapies used in Schizophrenia -- 12. Different phases of schizophrenia patients: from the psychological perspective -- 13. Stigmatizing Attitudes Towards Patients with Schizophrenia Among Medical Professionals and General Population -- 14. Rehabilitation of Schizophrenia-Practical Interventions -- 15. Consumption of Cannabis: A risk factor or a therapeutic agent for patients with Schizophrenia -- 16. Medical Imaging and Schizophrenia: A Study on State-of-art Applications -- 17. Schizophrenia and its Effect on Marital Satisfaction -- 18. The mortality rate in schizophrenia.

Description / Table of Contents: Chapter 1 A short introduction to vaccines -- Chapter 2 Thermostability of vaccines -- Chapter 3 Drying technologies for vaccines -- Chapter 4 Aseptic spray drying technology -- Chapter 5 Design of experiment studies and scale-up -- Chapter 6 Applications of spray dried vaccines.-Chapter 7 Conclusions and future perspectives of spray-dried vaccines.

Description / Table of Contents: Part I. Microscopy -- Chapter 1. Advances in Microscopy and Its Applications with Special Reference to Fluorescence Microscope: An Overview -- Chapter 2. Visualisation of Host-Pathogen Communication -- Chapter 3. A Review of Pathology and Analysis of Approaches to Easing Kidney Disease Impact: Host-Pathogen Communication and Biomedical Visualization Perspective -- Part II. Radiology and Patient Care -- Chapter 4. The Evolution of Equipment and Technology for Visualising the Larynx and Airway -- Chapter 5. The Impact of Technological Innovation on Dentistry -- Chapter 6. Advanced 3D Visualization and 3D Printing in Radiology -- Chapter 7. 3D Visualisation of the Spine -- Part III. Anatomy Education -- Chapter 8. Visualization in Anatomy Education -- Chapter 9. Visualizing Anatomy in Dental Morphology Education -- Chapter 10. Flashcards: The Preferred Online Game-Based Study Tool Self-Selected by Students to Review Medical Histology Image Content.

Description / Table of Contents: 1 The search for the nature of the soul -- 2 The functional neuroanatomy of the limbic system -- 3 Neuro- and psychopharmacology -- 4 Neurophysiology -- 5 Developmental neurobiology -- 6 Emotion, motivation, personality and their neurobiological foundations -- 7 Neurobiological consequences of early stress experiences -- 8 Psychological and neurobiological foundations of consciousness -- 9 Nature, diagnosis and classification of mental illness -- 10 Psyche and mental illness - addiction -- 11 Psychotic illness ("schizophrenia") -- 12 Affective disorders using the example of unipolar depression -- 13 Anxiety disorders -- 14 Neuropsychotherapy - psychotherapy methods and their effects -- 15 Psychoneuroscience and its significance for practice. .

Description / Table of Contents: 1. Implications of renin-angiotensin system in health and disease -- 2. Renin angiotensin system and aging -- 3. The interplay of the renin-angiotensin system and solid organ transplantation -- 4. Correlation between renin angiotensin system and infectious disease -- 5. Emerging contributions of endocrine pathophysiology in virus-related infectious disease -- 6. Understanding the renin-angiotensin system in coronavirus disease 2019 -- 7. Metabolomics approach in differentiating RAS responses in ARDS (Acute respiratory distress syndrome) and SAR-CoV-2 -- 8. A Comprehensive review of the impact of the renin angiotensin system in the liver, lung, infectious diseases and cancers -- 9. Application of biosensors for monitoring changes in renin angiotensin system (RAS) in cancers and lung diseases -- 10. Bioinformatics study on renin angiotensin in lung, and liver cancer using plant-based extracts -- 11. Role of renin-angiotensin system in the pathogenesis and progression of non-alcoholic fatty liver -- 12. The classical and nonclassical renin-angiotensin-aldosterone system in liver cirrhosis -- 13. Renin-angiotensin-aldosterone system role in organ fibrosis -- 14. Role of renin angiotensin-aldosterone system in kidney homeostasis -- 15. Renin-angiotensin system in chronic kidney disease: Implications in stroke outcome -- 16. The renin-angiotensin system and cancer -- 17. Renin-angiotensin system and cancer: From laboratory to clinics -- 18. Role of renin-angiotensin system in cancer cachexia -- 19. Renin angiotensin system activity in different cancers: Mechanistic insight and preclinical studies -- 20. The new dimension of the renin-angiotensin system in the hallmarks of cancer -- 21. Renin-angiotensin system in hematological malignancies -- 22. Renin angiotensin system (RAS): The common thread between cancer and heart failure -- 23. Renin-angiotensin system: a potential therapeutic target for colorectal cancer -- 24. Anticancer role of natural phenolic acids by targeting angiotensin-converting enzyme (ACE) -- 25. Angiotensin-(1-7): A Prospective Cancer Therapeutic.

Description / Table of Contents: Preface (Brianne K. Connizzo, Lin Han, Robert L. Sah) -- Scientific Impact -- Chapter 1. Aggrecan and Hyaluronan: The infamous Cartilage Polyelectrolytes- Then and Now (Anna Plaas, Meghan Moran, John Sandy, Vincent Hascall) -- Chapter 2. Understanding the Influence of Local Physical Stimuli on Chondrocyte Behavior (Byumsu Ki, Lawrence J. Bonassar) -- Chapter 3. Multiscale In Silico Modeling of Cartilage Injuries (Rami K. Korhonen, Atte S.A. Eskelinen, Gustavo A. Orozco, Amir Esrafilian, Cristina Florea, and Petri Tanska) -- Chapter 4. In Vitro Models and Proteomics in Osteoarthritis Research (Martin Rydén, Patrik Önnerfjord) -- Chapter 5. Nanomechanics of Aggrecan: A New Perspective on Cartilage Biomechanics, Disease and Regeneration (Chao Wang, Elizabeth R. Kahle, Lin Han) -- Chapter 6. Computational Modelling for Managing Pathways to Cartilage Failure (Saeed Miramini, David W. Smith, Bruce S. Gardiner, Lihai Zhang) -- Chapter 7. Gene Delivery to Chondrocytes (Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De la Vega) -- Chapter 8. Mechanical Articular Cartilage Injury Models and Their Relevance in Advancing Therapeutic Strategies (Bodo Kurz, Melanie L Hart, Bernd Rolauffs) -- Chapter 9. Hip Osteoarthritis: Bench to Bedside Perspective (Young-Jo Kim) -- Chapter 10. Harnessing Growth Factor Interactions to Optimize Articular Cartilage Repair (Stephen B. Trippel) -- Personal Tributes -- Index.

Description / Table of Contents: 1-Attitudes and smoking prevalence among undergraduate students in central Greece -- 2-Care of patients with Alzheimer’s disease -- 3-Regulation of antioxidant enzymes levels in rat brain -- 4-NIRS-based assessment of cerebral oxygenation during high definition anodal transcranial direct current stimulation in patients with posttraumatic encephalopathy -- 5-Cerebral critical closing pressure at concomitant traumatic brain injury -- 6-The role of inflammatory biomarkers as a diagnostic tool for possible late-life cognitive decline and dementias -- 7-The Development of Antisense RNA Treatments using Engineered Protein Substrates -- 8-Biomarker-driven analysis using high-throughput approaches in neuroinflammation and neurodegenerative diseases -- 9-Sensitive and Stereo specific high-performance liquid chromatographic method for flurbiprofen in human plasma -- 10-Genotypic and Clinical Analysis of a Thalassemia Major Cohort: An Observational Study -- 11-Design and Validation of a New Diagnostic Tool for the Differentiation of Pathological Voices in Parkinsonian Patients -- 12-Effects of an 8-Week Stress Management Program in Women with Breast Cancer: A Randomized Controlled Trial -- 13-The Rosenberg Self-Esteem Scale: Translation and Validation in the Greek Language in Adolescents -- 14-Stress system activation analysis in Greek female adolescents: a bioimpedance study -- 15-Kisspeptin and the genetic obesity interactome -- 16-The importance of diagnostic and prognostic biomarkers identification and classification towards understanding ALS pathogenesis -- 17-Entropy in Cardiac Autonomic Nervous System of Adolescents with General Learning Disabilities or Dyslexia -- 18-Ebola virus disease and current therapeutic strategies; A review -- 19-Hyperbaric Oxygen Therapy effect on “Kinesia Paradoxa” Brain Circuits -- 20-Early and Very Early GRIM19 and MCL1 Expression are Correlated to Late Acquired Prednisolone Effects in a T-Cell Acute Leukemia Cell Line -- 21-Phospholipid Fatty Acid Profile of Spirulina platensis -- 22-Chronic systemic inflammation measured by bioimpedance technology before and after sleeve gastrectomy: a feasibility study -- 23-Synthesis and Biological Evaluation Substituted Thiophene Derivatives -- 24-Force spectroscopy in mechanical protein domains unfolding -- 25-Investigating the genetic component of Parkinson’s Disease -- 26-Urticaria from the Neurodermatological Perspective: A Temporal Analysis of Urticaria and Cognition -- 27-Novel Low-Noise CMOS Bioamplifier for the Characterization of Neurodegenerative Diseases -- 28-The Kentucky Inventory of Mindfulness Skills in Greek Undergraduate and Postgraduate Students -- 29-Synthesis, in silico stuiesand biological evaluation of 1, 3 ,4 oxadiazino indole derivatives -- 30-Designing and screening of new schiff bases of indole derivatives for anti-bacterial activity by in-silico methods and docking studies -- 31-Use of vitamin D bolus in fortified juice for improving vitamin D status in children with Cerebral Palsy -- 32-Microbes and the games they play -- 33-Impurity Profiling and Identification of 2,6 diisopropylphenol by Raman spectroscopy -- 34-Cultural Accommodation of the Strengthening Families Program for Parents and Young Adolescents 10-14: Greek Phase I & II Study -- 35-The effect of nutrients on Alzheimer’s disease biomarkers: A metabolomic approach -- 36-The impact of exercising in the quality of life of people with Aementia-Alzheimer disease -- 37-Advanced Health Technologies and Nanotechnologies in Neurodegenerative Diseases -- 38-Phenotype and genotype study in a case of frontometaphyseal dysplasia 1 -- 39-Craniofacial and neurological phenotype in a case of oculodentodigital syndrome -- 40-Clinical and molecular study of common thrombophilia mutation prothrombin G20210A -- 41-Prenatal genetic testing for X-linked hypohidrotic ectodermal dysplasia -- 42-Preimplantation genetic testing for spastic paraplegia type 3 -- 43-Synthesis, anti-inflammatory activity and in-silico studies of some new 3-({P-DIMETHYLAMINO}BENZYLIDENE YDRAZINYLIDENE)-1,3-DIHYDRO-2H-INDOLE-2-ONE DERIVATIVES -- 44-Design, characterization and docking studies of some novel isatin derivatives for anticonvulsant and antidepressant activity -- 45-Skin mirrors Brain: A Chance for Alzheimer’s Disease Research -- 46-Mitochondrial homeostasis in neurodegeneration and ageing -- 47-The Alzheimer's Disease Chronicles: will evidence triumph over adversity? -- 48-Liposomes: Production Methods and Application in Alzheimer’s Disease -- 49-Developing Treatments for Alzheimer’s and Related Disorders with Precision Medicine: A Vision -- 50-Biomarkers and Precision Medicine in Alzheimer’s Disease -- 51-The role of microRNAs in thrombosis -- 52-Photo-oxygenation: an innovative new therapeutic approach against amyloidoses.

Description / Table of Contents: Chapter 1: Interactions in cancer ecosystem -- Chapter 2: Local niche construction -- Chapter 3: Pre-metastatic niche -- Chapter 4: Emerging concepts in cluster metastasis -- Chapter 5: Neuronal regulation in cancer ecosystem -- Chapter 6: Endocrinal regulation in cancer ecosystem -- Chapter 7: Innate immune system in cancer ecosystem -- Chapter 8: Adaptive immune system in cancer ecosystem -- Chapter 9: Inflammation in cancer ecosystem -- Chapter 10: Metabolic regulation in cancer ecosystem -- Chapter 11: Vascular regulation in cancer ecosystem -- Chapter 12: Microbial interaction in cancer ecosystem -- Chapter 13: Viral interaction in cancer ecosystem -- Chapter 14: Evolution of cancer ecosystem -- Chapter 15: Driving force of cancer ecosystem -- Chapter 16: Modeling, visualizing and subtyping the cancer ecosystem -- Chapter 17: Bio-engineering methods to mimic cancer ecosystem -- Chapter 18: Cancer ecosystem-directed therapeutic strategies.

Description / Table of Contents: Section I: Neurodegenerative diseases -- Chapter 1: Nanowired delivery of cerebrolysin together with antibodies to amyloid beta peptide, phosphorylated tau and tumor necrosis factor alpha induces superior neuroprotection in Alzheimer's disease brain pathology exacerbated by sleep deprivation -- Chapter 2: Nanodelivery of histamine H3/H4 receptor modulators BF2649 and clobenpropit with antibodies to amyloid beta peptide in combination with alpha synuclein reduces brain pathology in Parkinson's disease -- Chapter 3: Co-administration of nanowired DL-3-n-butylphthalide (DL-NBP) together with mesenchymal stem cells, monoclonal antibodies to alpha synuclein and TDP-43 (TAR DNA-binding protein 43) enhance superior neuroprotection in Parkinson's disease following concussive head injury -- Chapter 4: Neuroprotective effects of nanowired delivery of cerebrolysin with mesenchymal stem cells and monoclonal antibodies to neuronal nitric oxide synthase in brain pathology following Alzheimer’s disease exacerbated by concussive head injury -- Section II: Central Nervous system Trauma -- Chapter 5: Co-administration of nanowired monoclonal antibodies to inducible nitric oxide synthase and tumor necrosis factor-alpha together with antioxidant H-290/51 reduces SiO2-nanoparticles induced exacerbation of pathophysiology of spinal cord trauma -- Chapter 6: Nanowired delivery of cerebrolysin with mesenchymal stem cells attenuates heat stress induced exacerbation of neuropathology following brain blast injury -- Chapter 7: Co-administration of nanowired oxiracetam and neprilysin with monoclonal antibodies to amyloid beta peptide and p-tau thwarted exacerbation of brain pathology in concussive head injury at hot environment -- Section III. Stress and Drugs of abuse -- Chapter 8: Nanowired delivery of mesenchymal stem cells with antioxidant compound H-290/51 reduces exacerbation of methamphetamine neurotoxicity in hot environment -- Chapter 9: TiO2-nanowired delivery of Chinese extract of Gingko biloba EGb-761 and bilobalide BN-52021 enhanced neuroprotective effects of cerebrolysin following spinal cord injury at cold environment -- Chapter 10: Nanowired delivery of curcumin attenuates methamphetamine neurotoxicity and elevates levels of dopamine and brain derived neurotrophic factor.

Description / Table of Contents: Chapter 1. History, origin and types of neurological disorders -- Chapter 2. Mechanistic approach involved in the progression of Neurodegenerative disorders -- Chapter 3. Isolation, characterization and differentiation of stem cells -- Chapter 4. Role of Stem cells as a protective agent against neurological complications -- Chapter 5. Mesenchymal stem cells and their application against neurodegenerative disorders -- Chapter 6. iPSCs and their role in amelioration of neurodegenerative disorders -- Chapter 7. Isolation, characterization and detailed history of exosomes derived from stem cells and their epigenetic biology -- Chapter 8. Stem cells vs exosomes: promising therapeutic approach and biomarkers agent against neurodegenerative disorders -- Chapter 9. Role of stem cells and derived exosomes as a novel therapeutic agent against neuroinflammation and stroke -- Chapter 10. Role of stem cells and derived exosomes as a novel therapeutic agent against Alzheimer’s and Parkinson's disease -- Chapter 11. Role of stem cells and derived exosomes and associated signalling molecules involved in neuroprotection -- Chapter 12. Exosome as nanoparticles against neurodegenerative disorders.

Description / Table of Contents: 1. Integrate and fire: RC circuits to model neurons and reward monkeys -- 2. Neuronal spike trains, stochastic point processes, and why George Gerstein’s papers are still worth reading -- 3. Visual Functions of Inferior Temporal Cortex -- 4. Early Days in the Gerstein Lab: Neuronal Plasticity in 1, 2, and 3 Dimensions -- 5. Patterns in Spike Trains -- 6. Introduction to the Gravity Papers -- 7. On correlations and interactions between neurons and with George Gerstein -- 8. Significance of Correlations between Spike Trains -- 9. Spatial-Temporal Spike Patterns -- 10. Does Cross Correlation Have a Unique Interpretation? -- 11. Neuronal Plasticity and my Experience Working with George L. Gerstein -- 12. Auditory Experiments and Modeling -- 13. Thinking about Analysis Methods with George in Philadelphia, Cambridge and Newcastle -- 14. Higher-order Correlations and Synfire Chains -- Nencki Award for George L. Gerstein.

Description / Table of Contents: Chapter 1. Lysine demethylation in pathogenesis -- Chapter 2. Targeting the LSD1/KDM1 Family of Lysine Demethylases in Cancer and Other Human Diseases -- Chapter 3. KDM2 demethylases as drug targets -- Chapter 4. Role of histone demethylase KDM3 (JMJD1) in transcriptional regulation and cancer progression -- Chapter 5. KDM4 demethylases as drug targets -- Chapter 6. KDM5 lysine demethylases in pathogenesis, from basic science discovery to the clinic -- Chapter 7. Context-dependent functions of lysine demethylases in physiology and disease -- Chapter 8. KDM7 demethylases as drug targets.

Description / Table of Contents: Part I. Advances in Microscopy for Visualization, Education and Healthcare Practice -- Chapter 1. Visualizing the Invisible: Microscopy and How It Affects Our Understanding of Cells and Tissues -- Chapter 2. Morphometric Image Analysis and Its Applications in Biomedicine Using Different Microscopy Modes -- Chapter 3. The Shift in Power from Conventional to Digital and Virtual Microscopy -- Chapter 4. How Visualizations Have Revolutionized Taxonomy: From Macroscopic, to Microscopic, to Genetic -- Chapter 5. Bright New World: Principles of Fluorescence and Applications in Spectroscopy and Microscopy -- Chapter 6. An Introduction to Particle Tracking Techniques with Applications in Biomedical Research -- Chapter 7. An Exploration of the Practice of CT Modalities to Evaluate Anterior Cranial Deformities in Craniosynostosis -- Part II. Anatomical and Cell Biology Education -- Chapter 8. The Use of Biomedical Imaging in Visuospatial Teaching of Anatomy -- Chapter 9. Ultrasound Imaging for Musculoskeletal Research -- Chapter 10. Skill Acquisition in Histology Education.

Description / Table of Contents: Chapter 1. Hematopoietic Stem Cell Development in Mammalian Embryos -- Chapter 2. Hematopoietic Stem Cells and Their Bone Marrow Niches -- Chapter 3. Emerging Roles of Epigenetic Regulators in Maintaining Hematopoietic Stem Cell Homeostasis -- Chapter 4. Metabolism in Hematopoiesis and Its Malignancy -- Chapter 5. The Origin of Clonal Hematopoiesis and Its Implication in Human Diseases -- Chapter 6. Ex vivo Expansion and Homing of Human Cord Blood Hematopoietic Stem Cells -- Chapter 7. N6-methyladenosine RNA Modification in Normal and Malignant Hematopoiesis -- Chapter 8. Immune System Influence on Hematopoietic Stem Cells and Leukemia Development -- Chapter 9. Learning from Zebrafish Hematopoiesis -- Chapter 10. Multi-lineage Differentiation from Hematopoietic Stem Cells -- Chapter 11. Gene Editing in Hematopoietic Stem Cells -- Chapter 12. Aging, Causes and Rejuvenation of Hematopoietic Stem Cells.

Description / Table of Contents: Soundscape – The Development of a New Discipline -- Soundscape: A Construct of Human Perception -- Soundscape: The Holistic Understanding of Acoustic Environments -- Soundscape and Urban Planning -- Architectural Soundscapes: Theories, Methods, and Practice -- Psychoacoustics in Soundscape Research -- Measurements and Techniques in Soundscape Research -- Triangulation as a Tool in Soundscape Research -- Soundscape and Health -- Hospital Soundscape -- How to Put Soundscape into Practice.

Description / Table of Contents: 1. Introductory chapter: Early applications and evolution of blockchain implementations in medicine -- 2. Can Blockchain Technology Change Contemporary Medicine As It Is Currently Understood? -- 3. The Current State of Healthcare Information Exchange (HIE) and Proposing a Blockchain HIE Infrastructure -- 4. An amalgamation of blockchain and connected health for combating COVID-19 -- 5. Applications of Blockchain Technology in the COVID-19 Era. 6. Distributed Ledgers and Immunity Passports: The Intersection of Clinical Medicine and Digital Technology -- 7. Digital Identity, Computational Reliabilism, and the Future of IOMT: Epistemic Reasoning and The Role of Blockchain in Removing Human Tampering from Pharmacovigilance Decision Making -- 8. Potential implementations of blockchain technology in patient safety: A high-level overview -- 9. Blockchain in Medical Education -- 10. Blockchain in Education: Linking Competency Assessment with Credentialing -- 11. Optimizing Blockchain Technology in Academic Medicine -- 12. Distributed Research Networks -- 13. Use of Blockchain Technology for Implantable Medical Device Tracking -- 14. Application of Blockchain Technology in Healthcare Supply Chains.

Description / Table of Contents: 1. Principles of molecular recognition -- 2. Theoretical Aspects -- 3. Molecular Recognition Units in Sensor Constructions -- 4. Binding blocks and Interfaces Designed for Sensing -- 5. Probing the properties of continuous media and interfaces -- 6. Detection of Ions and Low-molecular Targets -- 7. Detection of Biological Macromolecules and Recognition of harmful microbes -- 8. Sensing Inside the Living Cells -- 9. Ex-vivo Clinical Diagnostics -- 10. Imaging in vivo -- 11. Theranostics: Combining Targeting, Imaging and Therapy -- 12. Opening new horizons.

Description / Table of Contents: PART I. Iron, Brain Function and Behavior -- Chapter 1. Iron and Neuro-cognition -- Chapter 2. The Interplay Between Iron and Oxidative Stress in Brain Neurodegenerative Diseases -- Chapter 3. Specific Nutritional Therapeutic Approaches Targeting Iron Overload and Other Hallmarks of Brain Degenerative Diseases -- Chapter 4. Mediterranean Diet and Neuro-Cognition: Focus on Alzheimer disease -- PART II Brain disorders related to Iron -- Chapter 5. The Critical Roleplay of Iron Neurochemistry in Progression of Parkinson’s Disease -- Chapter 6. Iron-Calcium Crosstalk in Neurodegenerative Diseases -- Chapter 7. Iron and Alzheimer’s Disease -- Chapter 8. Iron and Multiple Sclerosis -- Chapter 9. Iron and Epilepsy -- Chapter 10. Iron and Subarachnoid Hemorrhage -- Chapter 11. Iron deficiency and psychiatric disorders -- Chapter 12. Iron and Neuro-developmental Disorders -- Chapter 13. Iron and Neuropathies.

Description / Table of Contents: The Architecture of the Presynaptic Release Site.-Cytomatrix Proteins in Presynaptic Terminal. - Multiple Modes of Fusion and Retrieval at the Calyx of Held Synapse -- Roles of SNARE Proteins in Synaptic Vesicle Fusion -- Calcium Sensors of Neurotransmitter Release. - Roles and Sources of Calcium in Synaptic Exocytosis -- Regulation of Presynaptic Calcium Channels -- Roles of mUnc13/UNC-13 and mUnc18/UNC-18 in Neurotransmitter Release. - The role of tomosyn in the regulation of neurotransmitter exocytosis. -Roles of complexins in Neurotransmitter Release. -Regulation of Neurotransmitter Release by AIPR-1/AIP and calstabins. - The Role of Potassium Channels in the Regulation of Neurotransmitter Release -- Roles of Neuropeptides in Synaptic Function. - Transsynaptic Regulation of Presynaptic Release Machinery in Central Synapses by Cell Adhesion Molecules. - Lipids and Secretory Vesicle Exocytosis -- Synaptic Vesicle Endocytosis.

Description / Table of Contents: Chapter 1. Introduction to multi-omics -- Part 1. Omics integration techniques -- Chapter 2. Biomedical applications: the need for multi-omics -- Chapter 3. Omics technologies and big data -- Chapter 4. Multi-omics data mining techniques: algorithms and software -- Part 2. Applications of multi-omics analyses -- Chapter 5. Multi-omics data analysis for cancer research: colorectal cancer, liver cancer and lung cancer -- Chapter 6. Multi-omics data analysis for inflammation disease research: correlation analysis, causal analysis and network analysis -- Chapter 7. Microbiome data analysis and interpretation: correlation inferences and dynamic pattern discovery -- Chapter 8. Current progress of bioinformatics for human health.

Description / Table of Contents: Chap 1. Research Environment -- Chap 2. Training, Supervision and Mentoring -- Chap 3. Research Procedures -- Chap 4. Safeguards -- Chap 5. Data Practices and Management -- Chap 6. Collaborative Working -- Chap 7. Publication and Dissemination -- Chap 8. Reviewing, Evaluating and Editing -- Chap 9. How to deal with allegations of misconduct.

Description / Table of Contents: 1. Introduction -- 2. Diversity and evolution of jellyfish visual systems, Mollusks -- 3. Scallops distributed eyes -- 4. Chiton dispersed visual systems, Annelids -- 5. Errant polychaetes Arthropods -- 6. Spider eyes -- 7. Myriapod eyes -- 8. Insect ocelli -- 9. Batflies, copepods or larval stomatopods -- 10 -- Hyperiid amphipods, Echinoderms -- 11. Brittle star vision -- 12. Starfish vision.

Description / Table of Contents: Editorial -- Dystonia in childhood - how insights from paediatric research enrich the network theory of dystonia -- Focal Dystonia and the Stress-Network -- Limbic influences in Musicians dystonia -- Network perspective on task-specific dystonia -- Electromyography as a method for distinguising dystonia-like behavior in mice -- Deep brain stimulation of the interposed cerebellar nuclei in a mouse model of dystonia -- Applications of Transcranial Magnetic Stimulation for understanding and treating dystonia -- Brain connectivity in dystonia: evidence from Magnetoencephalography -- Dysfunctional networks in functional dystonia -- Collicular-pulvinar-amygdala axis and adult-onset idiopathic focal dystonia syndrome -- Neuromodulation in dystonia -- Electrophysiological properties of pallidal cells in cervical dystonia patients undergoing unilateral DBS -- Clinical implications of dystonia as a neural network disorder.

Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. The Psychiatrist and Pathologist Aloysius Alzheimer and His Seminal Findings -- Chapter 3. Alzheimer’s Disease Research After 1945: The Recommencement -- Chapter 4. Alzheimer’s Research Goes Deeper – Ultrastructural Electron Microscopy Studies -- Chapter 5. Focus on Neurochemistry Led to the Cholinergic Hypothesis of Alzheimer’s Disease -- Chapter 6. The Glutamatergic-Hypothesis of Alzheimer’s Disease -- Chapter 7. Biochemistry and Genetics Points Out a Prime Suspect for Causing Alzheimer’s Disease -- Chapter 8. Getting to the Bottom of It: Amyloid Beta Peptide Is Derived from a Larger Precursor -- Chapter 9. Step by Step Towards an Amyloid Beta Peptide-Based Hypothesis of Alzheimer’s Disease -- Chapter 10. Concerns about the Amyloid Cascade Hypothesis and Reappraisals -- Chapter 11. Ignorance or Conspiracy? Or Just an Amyloid Firewall that Blocks Alternative Ideas? -- Chapter 12. In the Slip Stream of Amyloid: The Tau and Tangle Hypothesis -- Chapter 13. Focus on Tauopathies and Beyond -- Chapter 14. Alzheimer’s Research Gains Momentum and Spreads Out -- Chapter 15. The Amyloid Cascade Hypothesis Has to Deliver, Finally -- Chapter 16. Beyond APP, PSEN1, PSEN2, and APOE: What Else Does the Genome Tell Us? Chapter 17. Alternative Hypotheses and Observations that were Somehow Lost on the Way -- Chapter 18. Is the Persistence of the Amyloid Cascade Hypothesis a Result of Constant Confirmation Bias? -- Chapter 19. Driving Forces of Alzheimer’s Research Directions -- Chapter 20. Thirty Years after the Launch of the Amyloid Cascade Hypothesis: Is There a Shift of Gears at Last? -- Chapter 21. "If You Change the Way You Look at Things, Things You Look at Change".

Description / Table of Contents: High Resolution Imaging Mass Spectrometry of Human Donor Eye: Photoreceptor Cells and Basal Laminar Deposits of Age-related Macular Degeneration -- The non-canonical role of Complement Factor H in Retinal Pigment Epithelium (RPE) cells and implications for Age-related Macular Degeneration -- Macular Pigment Carotenoids and Bisretinoid A2E -- Disturbed matrix metalloproteinases activity in age-related macular degeneraton -- Current views on Chr10q26 contribuiton to age-related macular degeneration -- Untargeted lipidomic profiling of aged human retina with and without age-related macular degeneration (AMD) -- Decoding Race and Age-Relation Macular Degeneration: GPR 143 Activity is the Key -- Peroxisome proliferator-activated receptor gamma coactivator 1 alpha ( PGC-1x): a transcriptional regulator at the interface of aging and age-related macular degeneration? -- Regulation of ABCA1 by miR-33 and miR-34a in the aging eye -- The role of gene expression regulation on genetic risk of Age-related Macular Degeneration -- Elastin layer in Bruch's membrane as a target for immunizatio or tolerization to modulate patthology in the mouse model of somke-induced ocular injury -- Repuprosing drugs for treatment of age-relation macular degeneration -- Extracellular Vesicle RNA Contents as Biomarkers for Ocular Diseases -- Proteomics of retinal extracellular vesicles: a reviw inot an unexplored mechanism in retinal health and AMD pathogenesis -- Prime Editing Strategy to Instally the PRHP2 c.828+1G A mutations -- Analysis of CRB1 Pathogenic Variants Correctable with CRISPR Base and Prime Editing -- Generation of an Avian Myeloblastosis Virus (AMV) Reverse Transcriptase Prime Editor -- Pre-existing neutralizing antibodies against different adeno-associated virus serotypes in humans and large animal models for gene therapy -- Optimization of Capillary-based Western Blotting for MYO7A -- AAV Serotypes and Their Suitability for Retinal Gene Therapy -- Gene Augmentation ofautosomal dominant CRX-associated retinopathies -- Txnip gene therapy of retinitis pigmentosa improves cone health Factors affecting readthrough of natural versus premature termination codons -- Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease -- Network biology and medcine to resuce: Applications for retinal disease mechanisms and therapy -- Non-sydromic Retinal Degeneration Caused by Pathogenic Variants in Joubert Syndrome Genes -- Exonic variants that affect splicing- an opportunity for "hidden" mutations causing inherited retinal diseases -- Enhanced S-cone Syndrome, a Mini-Review -- The role of microglia in Inherited Retinal Diseases -- CD68: potential contributor to inflammation and RPE cell dystrophy -- Gene Expression of Clusterin, Tissue Inhibitor of Metalloproteinase-1, and Their receptors in Retinal Pigment Epithelial Cells and Muller Glial Cells is Modulated by Inflammatory Stresses -- Axonal Transport Defects in Retinal Ganglion Cells -- Connexins biology in the pathophysiology of retinal diseases -- Role of Nuclear NAD +in Retinal Homeostasis -- Retinal pigmented epithelium-derived ectopic norrin does not promote intraretinal angiogenesis in transgenic mice -- Caveolin-1 Muller glia exist as heat-resistant,high molecular weight complexes -- Role of VLC-PUFAs in Retinal and Macular Degeneration -- Ocular amyloid , condensates, and aggregates - higher order protein assemblies participate in both retinal degeneration and function -- Photoreceptor ion channels in signaling and disease -- The role of peripherin-2 /ROM1 complexes in photoreceptor outer segment disc morphogenesis -- Human mutations in Arl3, a small GTPase involved inlipidated cargo delibery to the cilia cause retinatl dystropthy -- Genotype-Phenotype Association in ABCA4-Associated Retinopathy -- Retinal pathoconnectomics: A Window into Neurodegeneration -- The role of Ceramide in Inherited Retinal Disease Pathology -- Extracelluar Matix: the Unexplored Aspects of Retinal Pathologies and Regeneration -- Role of TFEB in diseases assocaited with lysosomal dysfunction -- Retinoic acid receptor -related oprhan receptors (RORs) in eye development and disease -- A novel mouse model for Late-Onset Retinal Degeneration (L-ORD) devekios RPE abnormalities due to the loss of C1qtnf5/Ctrp5 -- Comparison of mouse models of autosomal dominant retinitis pigmentosa due to P23H muations of Rhodopsin -- Compensatory Cone-Mediated Mechanisms in Inherited Retinal Degeneration Mouse Models: A Functional and Gene Expression Analsyis -- Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Sress and Promotes ER Protein Degradation in Cyclic Nucleotide-gated Channel Deficiency -- Mouse choroid proteome revisited: foucs on aging -- Morphological and functional comparison of mice models for retinitis pigmentosa -- Current Advancements in Mouse Models of Retinal Disease -- Single-cell Itrnacriptomic Profiling of Muller Glia in the rd10 Retina -- Methods for in vivo characterization of proteostatis in the mouse retina -- Absence or PRCD leads to dysregulation in lipie Homeostatis resulting in disorganizationof photorecptor outer segment structure -- Expansion Microscopy of Mouse Photoreceptro Cilia -- Rod photorecptor specific ablation of Metformin target, AMPK, in preclinical model of autosomal recessvie retinitis pigmentosa -- TLR2 is highly overexpressed in retinal myeloid cells in the rd10 mouse model of retinitis pigmentosa -- Environmental light has an essentail effrect on the diseasae expression in a dominant RPE65 mutation -- Microglia Preserve Visual Function in A Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant -- Measuring the release of lactate from wild-type and rd1 mouse retina -- Aerobic glycolysis in photorecptors supports energy demand in the absence of mitochondrial coupling -- Redox Status in Retinitis Pigmentosa -- Perspectives on retinal dolichol metabolism and visual deficits in dolichol metalbolism-associated inherited disorders -- Retinal metabolic profile on IMPG2 deficiency mice with subretinal lesions -- Glutathione-coating of liposomes enhances the delivery of hydrophillic cargo to the inner nuclear layer in retinal cultures -- Modification of Mueller glial cell fate and proliferation with the use of small molecules -- A potential neuroprotective role for pyruvate kinase 2 in retinal degeneration -- Critical role of VEGF as a direct regulator of photorecptor function -- Lysine Ubiquitylation Drives Rhodopsin Protein Turnover -- In-silico prediction of MYO!C Rhodopsin Interactions and its Significance in Protein Localization and Visual Function -- A ciliary branched actin netowrk drives photoreceptor disc morphogenesis -- Revisiting the daily timing of POS phagocytosis -- Inhibition of Bacterial Peoptidoglycan Cytopahty by Retina Pigment Epithelial PGRP2 Amidase -- Understanding ischemic retinopathies: the role of Succinate and its recpto^T mutation -- Inducing neural regeneratio nfrom glia using proneural bHLH transcription factors.

Description / Table of Contents: The world of Brain: from Aging Brain, Diseased Brain to Social Brain -- Cognitive Aging：How the Brain Ages -- Cognitive Decline Associated with Aging -- The Overview of Cognitive Aging Model -- The Emotional and Affective Disorders in Cognitive Aging -- The Mechanism of Socioeconomic Status and Stress Effects on Cognition -- The Aging Patterns of Brain Structure, Function and Energy Metabolism -- Characteristics of Brain Network during Cognitive Aging -- Biomolecular Markers of Brain Aging -- Neurobiological Mechanisms of Cognitive Decline Caused by Brain Aging -- The Early Stage of Abnormal Aging: Cognitive Impairment -- The Terminal Stage of Abnormal Aging: Dementia -- The Effect of Cognitive Rehabilitation Training and Its Neuroimaging and Physiology Evidence -- Lifestyle Regulation and Its Evidence: Changes brought from Adjusting Correlative Factors of Cognitive Aging -- The Effect of Traditional Chinese Medicine on Delaying Age-related Cognitive Decline and Its Evidence.

Description / Table of Contents: Chapter 1. Introduction and History of Meningiomas -- Chapter 2. Clinical Presentation and Prognosis -- Chapter 3. Imaging Characteristics of Meningiomas -- Chapter 4. Histopathology of Meningiomas -- Chapter 5. Skull Base Meningiomas -- Chapter 6. Spinal Meningiomas -- Chapter 7. Surgical Therapies -- Chapter 8. Radiation Therapies -- Chapter 9. Illustrative Cases -- Chapter 10. Advances in CNS Tumor Classification -- Chapter 11. Genomic Landscape -- Chapter 12. Radiation-Induced Meningiomas -- Chapter 13. Meningioma Predisposing Syndromes -- Chapter 14. Epigentic Landscape -- Chapter 15. Immune Profile -- Chapter 16. PDX Models/Mouse Models/Cell Lines -- Chapter 17. Novel Medical Therapies -- Chapter 18. Quality of Life in Menigioma Patients -- Chapter 19. Illustrative Cases: Revisited with Adjuvant Molecular Data -- Chapter 20. Future Directions in Management.

Description / Table of Contents: Preface -- Part I: Backscatter Coefficient methods -- Chapter 1. Quantitative Ultrasound: an Emerging Technology for Detecting, Diagnosing, Imaging, Evaluating, and Monitoring Disease (Ernie Feleppa) -- Chapter 2. Quantitative Ultrasound: Scattering theory (Michael Oelze) -- Chapter 3. Quantitative Ultrasound: Experimental implementation (Michael Oelze) -- Chapter 4. Extracting Quantitative Ultrasonic Parameters from the Backscatter Coefficient (Aiguo Han) -- Part II: Attenuation Estimation Methods -- Chapter 5. Attenuation Compensation and Estimation (Timothy Bigelow and Yassin Labyed) -- Chapter 6. Recent advances in attenuation estimation (Ivan Rosado Mendez) -- Part III: Envelope Statistics Methods -- Chapter 7. Review of envelope statistics models for quantitative ultrasound imaging and tissue characterization (Francois Destrempes and Guy Cloutier) -- Chapter 8. Information entropy and its applications (Po-Hsaing Tsui) -- Part IV: Ultrasound Computed Tomography -- Chapter 9. Ultrasound Tomography (Nicole Ruiter, Torsten Hopp, Michael Zapf and Hartmut Gemmek) -- Chapter 10. Full Wave Inversion and Inverse Scattering in Ultrasound Tomography/Volography (James Wiskin) -- Chapter 11. Clinical Importance of 3D Volography in Breast Imaging (John Klock) -- Part V: Acoustic microcopy -- Chapter 12. Acoustic Microscopy (Yoshifumi Saijo) -- Chapter 13. Advanced Topics in Quantitative Acoustic Microscopy (Cameron Hoerig and Jonathan Mamou) -- Part VI: Phantoms for Quantitative Ultrasound -- Chapter 14. Phantoms for Quantitative Ultrasound (Tim Stiles) -- Index.

Description / Table of Contents: Section I. Extraction Methods -- Chapter 1. Updated Methods of Extracellular Vesicles Isolation -- Section II. Extracellular Vesicles in Cardiovascular Disease -- Chapter 2. Extracellular Vesicles and Pathological Cardiac Hypertrophy -- Chapter 3. Extracellular Vesicles and Cardiac Aging -- Chapter 4. Extracellular Vesicles and Ischemic Cardiovascular Diseases -- Chapter 5. Extracellular Vesicles and Hypertension -- Chapter 6. Extracellular Vesicles and Coronary Artery Disease -- Chapter 7. Extracellular Vesicles and Vascular Inflammation -- Chapter 8. Extracellular Vesicles and Muscle Atrophy Treatment -- Section III. Extracellular Vesicles in Metabolic Diseases -- Chapter 9. Extracellular Vesicles and Fatty Liver -- Chapter 10. Extracellular Vesicles and Obesity -- Chapter 11. Extracellular Vesicles in Bone Remodeling and Osteoporosis -- Section IV. Therapeutic Implications -- Chapter 12. Diagnosis of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 13. Therapeutics of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 14. Gene Therapy of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Section V. Future Prospects -- Chapter 15. Prospective Advances of Extracellular Vesicles Investigation in Cardiovascular and Metabolic Research -- Chapter 16. Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 17. Extracellular Vesicle Release from Platelets and their Contributions to Thrombosis.

Description / Table of Contents: The Purinergic Signaling: Overview -- Adenosine A2A Receptor-containing Heteromers and Neuroprotection -- Purinergic Signaling in Brain Physiology -- Neurotrophic Actions of Adenosine and Guanosine: Implications for Neural Development and Regeneration? -- Purinergic Signaling in Neurogenesis and Neural Fate Determination: Current Knowledge and Future Challenges -- Purinergic Signaling in Autism Spectrum Disorder -- Purinergic Signaling in Depression -- Roles of Purinergic Receptors in Alzheimer's Disease -- Purinergic Signaling in Basal Ganglia Diseases: Parkinson's Disease -- A Step in the ALS Direction: Lessons from the Purinome -- Purinergic P2 Receptors in Epilepsy -- Purinergic Signaling in Neuroinflammation -- Purinergic Signaling in Brain Tumors -- Development of Purinergic Receptor Agonists and Antagonists -- Acupuncture for Counteracting P2X4 and P2X7 Receptor Involvement in Neuroinflammation.

Description / Table of Contents: Part I. History of Medical Illustration, Graphic Medicine, Humanizing Healthcare and Equitable Visualizations -- Chapter 1. Drawn Together: Merging the Worlds of Health and Comics Through Graphic Medicine -- Chapter 2. Medical Graphics and Graphic Medicine -- Chapter 3. Decolonising Visual Narratives in Global Health: The Case for Equitable and Ethical Imagery Use -- Chapter 4. Medical Illustration in Anatomy -- Chapter 5. Valuing Creativity in Biomedical Science Education: A Reflective Narrative -- Chapter 6. Biomedical Visualization in Embryology Education: A Scoping Review -- Chapter 7. A Framework for the Design, Production, and Evaluation of Scientific Visualizations -- Part II. Anatomical and Cell Biology Education -- Chapter 8. Palpation: The Art of Felt Anatomy -- Chapter 9. Teaching Histology with Analogies -- Chapter 10. Using the Hands for Learning Anatomy -- Chapter 11. Corporeal Pedagogy: Visualizing Anatomy Through Art, Archaeology and Medicine.

Description / Table of Contents: The promises and pitfalls of Virtual Reality -- Setting up your VR neuroscience laboratory -- Monitoring the autonomic system in VR -- Monitoring brain activity in VR: EEG and neuroimaging -- Eye-tracking and Pupillometry in VR -- VR for Movement and Action Science -- VR for Vision Science -- VR for Emotion -- VR for Thinking and Creativity -- VR for Social Cognition -- VR as a window into Consciousness -- Aging -- Learning -- Pain -- Cognitive and motor rehabilitation -- VR for Mental Health.

Description / Table of Contents: Chapter 1_Introduction to Pulmonary Diseases and OMICS approaches -- Chapter 2_Obstructive Pulmonary Diseases -- Chapter 3_COPD (Chronic Obstructive Pulmonar Diseases) -- Chapter 4_ Asthma -- Chapter 5_Other obstructive airway diseases like Bronchiectases, Focal airway narrowing -- Chapter 6_Restrictive Pulmonary Diseases (Common qualities and features with examples) -- Chapter 7_Interstitial Pulmonary fibrosis (IPF) -- Chapter 8_Sarcoidosis -- Chapter 9_ Other restrictive airway diseases like pneumonitis, pleural thickening -- Chapter 10_Vascular Diseases -- Chapter 11_Pulmonary hypertension -- Chapter 12_Pulmonary edema -- Chapter 13_ Other vascular diseases like Pulmonary Edema, Cor Pulmonale -- Chapter 14_Infectious Diseases -- Chapter 15_Tuberculosis -- Chapter 16_Cystic fibrosis -- Chapter 17_Pneumonia, COVID-19 and others -- Chapter 18_Neoplastic Diseases/Lung Cancer.

Description / Table of Contents: Recontextualizing Sustainability: Regulative and Instructional Discourse -- Learning culture, Competencies and Consequences for Sustainability -- Dealing with Uncertainty in a Transformative Education for Sustainable Development -- Education for Sustainable Development in a Culture of Digitality -- School Geography as Radical Global Citizen Education -- Sustainable Contradictions? The Prospect for an Eco-socialist School Geography -- Bringing Sustainability into the Classroom -- Subject Matter Knowledge and Sustainability – Implications for Classroom Instruction -- Teaching with Geographical Situations to Practice Sustainability -- Geography Education for Sustainable Development through Problem-based Learning -- Factors Affecting Geography Pre-service Teachers’ Perception about Education for Sustainable Development -- Geographical Knowledge and (Education for) Sustainable Development in Geography Curricula -- Preparing Pre-service Teachers for Practicing Sustainable Geographies through Online Technology Integration -- Practicing students SDG Strategies through Fieldwork – Exploring Student Perspectives on Green Urban Planning Models in a Nature Park -- Opportunities and Challenges in Geography Education to Practice Sustainability Education.

Description / Table of Contents: Humanistic study of urban images -- Delhi: Evolution of an urban region -- Images of Delhi in Indo-Anglian and Hindi literary works -- Delhi: As an idea -- Old Delhi (Shahjehanabad) and adjacent regions -- New Delhi and neighboring colonies -- Four authors and their perceptions of Delhi -- Epilogue.

Description / Table of Contents: Chapter 1 -- Inequities and inequalities in access to care. Chapter 2 -- Gender and health. Chapter 3 -- Disability and health. Chapter 4 -- Food security. Chapter 5 -- Water and sanitation. Chapter 6 -- Mining and health. Chapter 7 -- Climate change and health. Chapter 8 -- Ageing and health. Chapter 9 -- Non-communicable diseases. Chapter 10 -- Infectious diseases. Chapter 11 -- Social interventions and health. Chapter 12 -- Environmental intervention and health. .

Description / Table of Contents: Chapter 1. UNVEILING THE SMART CITY: How Smart is it? -- Chapter 2. SMART CITIES AND SUSTAINABILITY: How Smart City helps with sustainability -- Chapter 3. SMART CITIES AND CLIMATE CHANGE: How Smart City can help cool the planet -- Chapter 4. SMART CITIES AND REGENERATIVE APPROACHES: How design with Smart City tech can regenerate cities -- Chapter 5. SMART CULTURAL AND INCLUSIVE CITIES: How Smart City can help urban culture and inclusion -- Chapter 6. SMART CITIES AND THE URBAN ECONOMY: How Smart City can integrate good urban economies -- Chapter 7. CONCLUSIONS: Redefining Smart Cities.

Description / Table of Contents: Chapter 1 -Theoretical Foundations of Total Socioenvironmental System (TSES) -- Chapter 2-Analytical Frameworks of TSES -- Chapter 3 - Building Temporally Compatible TSES Dataset -- Chapter 4 - Empirically investigating time-series causality between grassland productivity and socio-environmental factors, Inner Mongolia as a Case Study -- Chapter 5 - Empirical evaluation of urban sustainability from underlying causal structures and legacy effects: The prefecture cities in China as a Case Study -- Chapter 6 - Constructing Spatially Compatible TSES Dataset: Examining Urban Declining in Southeast Michigan as the case study -- Chapter 7 -Empirically examining spatial processes of urban declining: Southeast Michigan as the case study -- Chapter 8 - Modeling grassland deterioration considering spatial variations and time-lag effects at a finer geographical scale -- Chapter 9 - Innovations, Limitations, and Future Directions of TSES.

Description / Table of Contents: Re-thinking cities and the urban: from the global to the local -- From the new world to multiple possible worlds: political geography, geopolitics and border studies -- New and emerging pathways for transport geography -- Geography and geographers in place and time: a view from the international geographical union’s commission on the history of geography -- Innovative development of modern agricultural geographic engineering -- Integrating Geography for Global Sustainability and the Earth's Future: the role of International Geographical Union Commission on Geography of Future Earth -- Global change and human mobility in the Anthropocene -- Contribution of Geography and Geospatial Technology to Cope with Hazards and Risks: Implications of GIS Development in Japan -- Marginality issues in a time of world reorganization -- Land Use and Land Cover Changes in a Global Environmental Change Context -- The Contribution of Geography -- Coastal Systems: the dynamic interface between land and sea -- Advances in karst geomoprhology and hydrogeology research in the last decade and its future direction for karst land use planning -- Achievements and challenges of geographical research in Africa -- Issues and dilemmas of local and regional development in geographical research.

Description / Table of Contents: Introduction -- The Physical Environment -- Biological Environment -- The First People -- People on the Landscape -- Making a Living -- Life at Home -- Conclusions.

Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Climate and weather: impact on the body -- Chapter 3: Climatic norms, definition periods. Methods for determining the areas of biological comfort/discomfort -- Chapter 4: Adaptation to marine climate -- Chapter 5: Influence of weather and climatic conditions on health Adaptation to the marine climate of Russian regions -- Chapter 6: Non-specific prevention of pre-disease states and diseases when adapting to a maritime climate -- Chapter 7: Conclusion.

Description / Table of Contents: Part 1: Triestino Geographical Thought -- Chapter 1. Becoming geographer in Trieste: autobiographical essay, with a reflection on the nature of Geography -- Chapter 2. Living in the borderlands: political geography, geopolitics and advocacy in the Triestino School of Geography during the long 20th Century -- Part 2: Historical Geographyas Method: Producing Geopolitics From The Julian Region -- Chapter 3 Urbanization processes in a transnational area. An application of the rank-size rule to the Austrian Littoral (1849-1918) -- Chapter 4. Gorizia Nova, aka “New Gorizia:” a Euro-city on the border between Italy and Slovenia. A recommendation for local level territorial changes after Slovenia joined the European Union in 2004. Chapter 5. Inland areas and border regions: a geopolitical interpretation. Comparing the marginalization of Trieste and Umbria as an example of the dynamics of borderlands vs. remote inland areas. Part 3: From Trieste To The World: Deploying Triestino Geographical Thought To Grand Geopolitics In Europe And Beyond -- Chapter 6. The reshaping of German-Yugoslav Space from a middle European Point of view. Paper presented at the 2nd IBRU Conference, held in Durham, UK, on July 18-21, 1991 -- Chapter 7. Europe. The many reasons of an epoch-spanning crisis. A long-term geo-historical and geo-economics analysis of the obstacles to European integration -- Chapter 8. A century of struggles. A comparison of multiple geopolitical agendas in Europe, the US and beyond -- Chapter 9. Cycles of geopolitical (dis)order, as determined by interactions between spatial systems. A theoretical model of the systemic drivers of geopolitics.