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  • Books  (2)
  • Biomedical Research.  (2)
  • Cham :Springer International Publishing :  (2)
  • Berlin : Akad.-Verl.
  • Berlin [u.a.] : Langenscheidt
  • Washington, DC : United States Gov. Print. Off.
  • 576.5  (2)
Collection
  • Books  (2)
Publisher
  • Cham :Springer International Publishing :  (2)
  • Berlin : Akad.-Verl.
  • Berlin [u.a.] : Langenscheidt
  • Washington, DC : United States Gov. Print. Off.
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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Genetics. ; Medicine Research. ; Biology Research. ; Cytology. ; Medical genetics. ; Genetics and Genomics. ; Biomedical Research. ; Cell Biology. ; Medical Genetics.
    Description / Table of Contents: Biology of Chromatin -- Chromatin Dynamics -- Cellular Memory -- Dosage Compensation Systems -- Genomic Imprinting -- RNA-based Mechanisms of Gene Silencing -- Regeneration and Reprogramming -- Epigenetics and Cancer -- Epigenetics and Metabolism.
    Abstract: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease.
    Type of Medium: Online Resource
    Pages: XII, 215 p. 81 illus., 77 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030686703
    Series Statement: Learning Materials in Biosciences,
    DDC: 576.5
    Language: English
    Location Call Number Expected Availability
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Genetics. ; Bioinformatics. ; Medicine Research. ; Biology Research. ; Genetics and Genomics. ; Bioinformatics. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Next Generation Sequencing (NGS)- What can be sequenced? -- Opportunities and Perspectives of NGS Applications in Cancer Research -- Chapter 3. Library Construction for NGS -- Chapter 4. NGS Technologies -- Chapter 5. Computer Setup -- Chapter 6. Introduction to Command Line -- Chapter 7. NGS Data -- Chapter 8. Reference Genome -- Chapter 9. Alignment -- Chapter 10. Identification of Genetic Variants and de novo Mutations Based on NGS -- Chapter 11. Design and Analysis of RNA Sequencing Data -- Chapter 12. Design and Analysis of Epigenetics and ChIP-Sequencing Data -- APPENDIX.
    Abstract: This textbook provides step-by-step protocols and detailed explanations for RNA Sequencing, ChIP-Sequencing and Epigenetic Sequencing applications. The reader learns how to perform Next Generation Sequencing data analysis, how to interpret and visualize the data, and acquires knowledge on the statistical background of the used software tools. Written for biomedical scientists and medical students, this textbook enables the end user to perform and comprehend various Next Generation Sequencing applications and their analytics without prior understanding in bioinformatics or computer sciences.
    Type of Medium: Online Resource
    Pages: XII, 218 p. 54 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030624903
    Series Statement: Learning Materials in Biosciences,
    DDC: 576.5
    Language: English
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
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