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  • 2020-2024  (168)
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  • 571.978  (85)
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  • 1
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Cancer Therapy. ; Tumour Biomarkers.
    Description / Table of Contents: Part 1. CTC Technologies -- Affinity -- Physical -- ctDNA -- miRNA -- Exosomes -- Part 2 -- Biology of CTC -- Dormancy -- Culture -- EMT -- ctDNA and Exosomes -- Cells in circulation with CTC -- Part 3 -- CTC Analysis -- IHC, FISH, and other molecular assays -- Functional characterization -- Advanced microscopy and AI -- Analysis of non-cellular circulating markers -- Part 4 -- Clinical Applications of the Liquid Biopsy -- Early detection and cancer screening -- Prognosis and therapeutic monitoring -- Applications in Clinical Trials -- Applications in Drug Development.
    Abstract: It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other emerging aspects of the liquid biopsy, including circulating tumor DNA and methylated DNA (ctDNA, ct meDNA), ctRNA, ct miRNA, circulating tumor proteins (and other) biomarkers and circulating tumor derived exosomes (ctExosomes).
    Type of Medium: Online Resource
    Pages: XXI, 668 p. 77 illus., 72 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031229039
    Series Statement: Current Cancer Research,
    DDC: 571.978
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Cancer Treatment. ; Neurosciences. ; Immunotherapy. ; Cancer Biology. ; Cancer Therapy. ; Neuroscience. ; Cancer Microenvironment. ; Immunotherapy.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Neuronal influence on cancer initiation and growth -- Chapter 2.1 Paracrine signaling in CNS primary tumors and brain metastases -- Chapter 2.2 Paracrine signaling in PNS primary tumors -- Chapter 3. Neuronal influence on cancer invasion and metastasis including perineurial invasion -- Chapter 4. Neurotrophic activity of tumors -- Chapter 5. Cancer interactions with Schwann cells -- Chapter 6. Cancer-glial interactions -- Chapter 7. Neuron-cancer synaptic and other electrical signaling -- Chapter 8. Neuro-immune interactions system and immuno-oncology -- Chapter 9. Nervous system interactions with non-immune elements in the cancer microenvironment -- Chapter 10. Cancer-induced remodeling of the nervous system -- Chapter 11. Cancer and pain -- Chapter 12. Systemic interactions of cancer and the impact on the nervous system -- Chapter 13. Tools and model systems to study nerve-cancer interactions -- Chapter 14. Conclusions and Future Directions.
    Abstract: This volume is the first on the market to address and discuss the emerging field of cancer neuroscience. Edited by pioneers in the field with contributions from top researchers, the volume serves as a comprehensive overview of the role of nerves in tumorigenesis and cancer progression. Chapters will address how the innervation of tumors can serve as both prognostic and predictive biomarkers as well as actionable therapeutic targets. Authors will describe current research efforts, and future directions for study and translation to the clinic. It is becoming increasingly apparent that certain treatments will need to consider interactions between the nervous system and cancer, and the novel concepts presented in the book address related accumulating evidence regarding therapeutic strategies. This unique volume will be useful for cancer researchers, neuroscientists, cancer biologists, oncologists, and others looking to gain a greater understanding of this emerging field.
    Type of Medium: Online Resource
    Pages: XII, 202 p. 21 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031324291
    DDC: 571.978
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Cancer. ; Cancer Treatment. ; Tumors Immunological aspects. ; Immunotherapy. ; Cancer Genetic aspects. ; Stem cells. ; Cancer Biology. ; Cancer Therapy. ; Tumour Immunology. ; Immunotherapy. ; Cancer Genetics and Genomics. ; Cancer Stem Cells.
    Description / Table of Contents: Interdisciplinary Approach in Hepatobiliary Cancers -- Liver Cancer: Interdisciplinary Approach -- The Immune System in Liver Cancer: From Beginning to Progression -- The Tumor Microenvironment in Hepatocellular Carcinoma -- Metabolic Alterations of Hepatocellular Cancer Stem Cells -- Τhe Role of Senescence in NASH-related HCC -- Regulators of Genetic Risk for the Progression of Non-alcoholic Fatty Liver Disease to Hepatocellular Carcinoma: Reconstruction of Transcriptional Network and Signature-Based Metabolic Profiling -- Tumor Microenvironment and Immunotherapy in Advanced Biliary Tract Cancers -- Fibrosis and Immunotherapy in Hepatocellular Carcinoma -- Liver Cancer and the Curative Potential of Nanomedicine -- Locoregional Therapies for Hepatocellular Carcinoma -- Drug Resistance in Hepatocellular Carcinoma -- Liver Stereotactic Body Radiotherapy.
    Abstract: Hepatobiliary cancers, including hepatocellular carcinoma and biliary tract cancers, have high rate of mortality and low survival rate. The third volume of the “Interdisciplinary Cancer Research” series, entitled “Hepatobiliary Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of hepatobiliary cancers and therapeutic modalities and presents the most updated and peer-reviewed chapters on hepatobiliary cancers. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on hepatobiliary cancers.
    Type of Medium: Online Resource
    Pages: XI, 365 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031445286
    Series Statement: Interdisciplinary Cancer Research, 3
    DDC: 571.978
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Cancer. ; Cancer Treatment. ; Oncology. ; Immunotherapy. ; Tumors Immunological aspects. ; Nanomedicine. ; Cancer Biology. ; Cancer Therapy. ; Oncology. ; Immunotherapy. ; Tumour Immunology. ; Cancer Nanotechnology.
    Description / Table of Contents: Interdisciplinary Approach in Gastrointestinal Cancers -- Gastrointestinal Cancers: What Is the Real Board of Microenvironment and the Role of Microbiota-Immunity Axis -- Epithelial-Mesenchymal Transition in Gastrointestinal Cancer: From a Basic to a Clinical Approach -- Metabolomics of Gastrointestinal Cancers -- Deregulation of Immune System in Gastric Cancer Development, How Immune Nutrition Might Restore the Functions of Immune Cells -- Helicobacter pylori Virulence Factors, Pathogenicity, and Gastric Cancer -- Gastric Cancer and Helicobacter pylori -- Role of Neuromodulators in Regulation of the Tumor Microenvironment of Gastric and Colorectal Cancers -- The Role of Tumor Microenvironment in Colon Cancer -- Unraveling the Esophageal Cancer Tumor Microenvironment: Insights and Novel Immunotherapeutic Strategies -- The Interplay Between Immunity and Gut Microbiota in Colon Cancer -- Immunotherapy in Gastrointestinal Cancer Focusing on CAR-T Cell Therapy -- Development of Biocompatible Nanocarriers for the Treatment of Colorectal Cancer -- Challenges of Onco-therapeutics in Early Onset Colorectal Cancer -- Unintentional Weight Loss and Malnutrition After Esophageal Cancer and Treatment -- Current Clinical Landscape of Immunotherapeutic Approaches in Pancreatic Cancer Treatment. The Tumor Microenvironment in Pancreatic Cancer and Challenges to Immunotherapy. .
    Abstract: Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume. The fourth volume of the “Interdisciplinary Cancer Research” series, entitled “Gastrointestinal Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers.
    Type of Medium: Online Resource
    Pages: XI, 404 p. 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031483714
    Series Statement: Interdisciplinary Cancer Research, 4
    DDC: 571.978
    Language: English
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  • 5
    Keywords: Cancer. ; Oncology. ; Medical screening. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Oncology. ; Cancer Screening. ; Cancer Therapy. ; Tumour Biomarkers.
    Description / Table of Contents: Chapter 1. Introduction: The Application of AI in Precision Oncology: Tailoring Diagnosis, Treatment, and the Monitoring of Disease Progression to the Patient -- Part I. Artificial Intelligence for Screening, Diagnosis, Monitoring in Precision Oncology -- Chapter 2. Application of AI in Novel Biomarkers Detection that Induce Drug Resistance, Enhance Treatment Regimens and Advancing Precision Oncology -- Chapter 3. Use of Artificial Intelligence in Implementing Mainstream Precision Medicine to Improve Traditional Symptom-driven Practice of Medicine: Allowing Early Interventions and Tailoring better-personalized Cancer Treatments -- Chapter 4. AI as a Novel Approach for Exploring ccfNAs in Personalized Clinical Diagnosis and Prognosis: Providing Insight into the Decision-Making in Precision Oncology -- Chapter 5. AI-Enhanced Digital Pathology and Radiogenomics in Precision Oncology -- Part II. Artificial Intelligence and Omics in Precision Oncology -- Chapter 6. Epigenetics Analysis Using Artificial Intelligence in the Era of Precision Oncology -- Chapter 7. Association of Metabolomics with AI in Precision Oncology: Emerging Perspectives for More Effective Cancer Care -- Chapter 8. Artificial Intelligence Application to Microbiomics Data for Improved Clinical Decision Making in Precision Oncology -- Part III. Artificial Intelligence in Cancer Therapy and the Clinical Applications -- Chapter 9. AI and Nanotechnology in Realizing the Goal of Precision Medicine: Tailoring the Best Treatment for Personalized Cancer Treatment -- Chapter 10. Artificial Intelligence-Based Medical Devices Revolution in Cancer Screening: Impact into Clinical Practice -- Chapter 11. Intelligent Drug Design and Use for Cancer Treatment: The Roles of AI and Precision Oncology in Targeting Patient-Specific Splicing Profiles -- Chapter 12. Applying Artificial Intelligence Prediction Tools for Advancing Precision Oncology in Immunotherapy: Future Perspectives in Personalized Care -- Chapter 13. Employing AI-Powered Decision Support Systems in Recommending the Most Effective Therapeutic Approaches for Individual Cancer Patients: Maximizing Therapeutic Efficacy -- Chapter 14. AI-Pathway Companion in Clinical Decision Support: Enabling Personalized and Standardized Care Along Care Pathways in Oncology -- Chapter 15. AI Tools Offering Cancer Clinical Applications for Risk Predictor, Early Detection, Diagnosis, and Accurate Prognosis: Perspectives in Personalised Care -- Chapter 16. Conclusion and Insights into the Future of AI in Precision Oncology.
    Abstract: This book highlights the use of artificial intelligence (AI), big data and precision oncology for medical decision making in cancer screening, diagnosis, prognosis and treatment. Precision oncology has long been thought of as ideal for the management and treatment of cancer. This strategy promises to revolutionize the treatment, control, and prevention of cancer by tailoring tests, treatments and predictions to specific individuals or population groups. In order to accomplish these goals, vast amounts of patient or population group specific data needs to be integrated and analysed to be able to identify key patterns or features which can be used to define or characterize the disease or the response to the disease in these individuals. These patterns or features can be as varied as molecular patterns or features in medical images. This level of data analysis and integration can only be achieved through the use of AI. The book is divided into three parts starting with a section on the use of artificial intelligence for screening, diagnosis and monitoring in precision oncology. The second part: Artificial intelligence and Omics in precision oncology, highlights the use of AI and epigenetics, metabolomics, microbiomics in precision oncology. The third part covers artificial intelligence in cancer therapy and its clinical applications. It also highlights the use of AI tools for risk prediction, early detection, diagnosis and accurate prognosis. This book, written by experts in the field from academia and industry, will appeal to cancer researchers, clinical oncologists, pathologists, medical students, academic teaching staff and medical residents interested in cancer research as well as those specialising as clinical oncologists.
    Type of Medium: Online Resource
    Pages: XIV, 315 p. 64 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031215063
    DDC: 571.978
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Oncology. ; Cancer Biology. ; Biomedical Research. ; Oncology.
    Description / Table of Contents: Part I: Molecules, Genes, Cells and Mechanisms -- Chapter 1: An Introduction to Human Cancers -- Chapter 2: Cancer Genetics -- Chapter 3: DNA Damage and DNA Repair -- Chapter 4: Oncogenes -- Chapter 5: Tumor Suppressor Genes -- Chapter 6: Cancer Pathways -- Chapter 7: Cell Death and Replicative Senescence in Cancer -- Chapter 8: Cancer Epigenetics -- Chapter 9: Invasion and Metastasis -- Part II: Human Cancers -- Chapter 10: Leukemias And Lymphomas -- Chapter 11: Pediatric Cancers -- Chapter 12: Cancers of the Skin -- Chapter 13: Colorectal Cancer -- Chapter 14: Bladder Cancer -- Chapter 15: Lung Cancer -- Chapter 16: Renal Cell Carcinomas -- Chapter 17: Liver Cancer -- Chapter 18: Gastric Cancer -- Chapter 19: Breast Cancer -- Chapter 20: Prostate Cancer -- Part Iii: Prevention, Diagnostics and Therapy -- Chapter 21: Cancer Prevention -- Chapter 22: Cancer Diagnostics -- Chapter 23: Cancer Therapy.
    Abstract: This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers. Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.
    Type of Medium: Online Resource
    Pages: XXI, 542 p. 229 illus., 221 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031162862
    DDC: 571.978
    Language: English
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  • 7
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Cancer Treatment. ; Cancer Genetic aspects. ; Cancers. ; Cancer Therapy. ; Cancer Genetics and Genomics.
    Description / Table of Contents: Chapter 1 An introduction to breast cancer -- Chapter 2 Current treatment approaches to breast cancer. Chapter 3 Introduction to cell cycle and its regulators -- Chapter 4 Cell cycle and cancer -- Chapter 5 cell cycle dysregulation in breast cancer -- Chapter 6 Molecular Subtypes of breast cancer and CDK dysregulation -- Chapter 7 Breast tumor micro environment and CDks -- Chapter 8 CDK Dysregulation in Breast Cancer: A Bioinformatics Analysis -- Chapter 9 CDK1 Dysregulation in Breast Cancer -- Chapter 10 CDK4/CDK6 dysregulation in estrogen positive receptor breast cancers -- Chapter 11 Therapeutic implications of CDKs in Breast Cancer -- Chapter 12 Novel CDK Inhibitors in Breast Cancer -- Chapter 13 Targeting CDKs with other chemotherapeutic drugs- A combinatorial approach -- Chapter 14 CDKs in cell-cycle progression and therapeutic strategies in Human breast cancer -- Chapter 15 CDk inhibitor for treatment of breast cancer -- Chapter 16 Response of therapy in cell cycle regulatory genes in breast cancer -- Chapter 17 Different cyclins and their significance in Breast cancer.
    Abstract: This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer.
    Type of Medium: Online Resource
    Pages: XVII, 373 p. 133 illus., 92 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811989117
    DDC: 571.978
    Language: English
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  • 8
    Keywords: Cancer. ; Cancer Genetic aspects. ; Oncology. ; Therapeutics. ; Cancer Biology. ; Cancer Genetics and Genomics. ; Oncology. ; Therapeutics.
    Description / Table of Contents: Chapter 1 Evolution of translational cancer therapeutics -- Chapter 2 Oncology: Way forward from clinical and molecular diagnosis to treatment -- Chapter 3 Oncogenic genomics alterations in cancer patient -- Chapter 4 Altered mRNA expression profiles in cancer patients -- Chapter 5 microRNAs and long non-coding RNAs as key targets -- Chapter 6 Oncogenic alterations translated into diagnostics -- Chapter 7 Precision medicine in oncology -- Chapter 8 Precision medicine – translation of individualistic treatment in oncology -- Chapter 9Pharmacogenetics and Pharmacogenomics in Precision Medicine -- Chapter 10 Pharmacogenetic factors in pharmacodynamic/pharmacokinetic (PD/PK) modulations of medicines -- Chapter 11 Biomarkers in Precision Medicine in oncology -- Chapter 12 Bioinformatics and biostatistics in Precision Medicine -- Chapter 13 Omics in Precision medicine -- Chapter 14 Translational therapeutic targets : from bench to clinical trials -- Chapter 15 Strength of integartive genomic alterations, precision medicine and therapeutic targets as treatment choice in patient care.
    Abstract: This book describes translational cancer therapeutics and the way forward from clinical and molecular diagnosis to treatment. In addition, genomics alterations, microRNAs, and long non-coding RNAs translate precision medicine for the individualistic therapy of cancer patients. It describes the involvement of various pharmacogenetic factors in pharmacodynamic/pharmacokinetic (PD/PK) modulations of medicines. Indeed, the role of bioinformatics and biostatistics, considering the extensive data analysis serving precision medicine approaches, has also been entertained in the present book. Therefore, intended book demonstrates the successful medical evidence for the use of precision medicine in the treatment of cancer and its future clinical perspectives. It fills the gaps in cancer biology and precision medicine with its up-to-date content and well-designed chapters. It will serve as a valuable resource for science, medical students, and interdisciplinary researchers. It is a very welcome addition for the scientific community, research centers, and university-industry research collaborators to find out a complete capsular package about cancer drug targets, precision, and personalized medicine (including an introduction to cancer cell signaling, genomic alterations, miRNA targeting, pharmacogenetics, biomarkers, and metabolomics in precision medicine, etc.) at a single platform.
    Type of Medium: Online Resource
    Pages: XVI, 274 p. 23 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819915293
    DDC: 571.978
    Language: English
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  • 9
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Cancer. ; Cancer Treatment. ; Stem cells. ; Cytology. ; Medical genetics. ; Immunology. ; Cancer Biology. ; Cancer Therapy. ; Cancer Stem Cells. ; Cell Biology. ; Medical Genetics. ; Immunology.
    Description / Table of Contents: Interdisciplinary Approaches in Cancer Research -- Role of Immune Cells in the Tumor Microenvironment -- Spatial Transcriptomic Approaches for Understanding the Tumor Microenvironment (TME) -- Role of Mesenchymal Stem/Stromal Cells in Cancer Development -- Cancer-associated Fibroblasts and Their Role in Cancer Progression -- The Role of Tumoroids in Cancer Research -- Myokines Expression in Cancer Cachexia -- Epigenetics in Cancer Biology -- Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation -- Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity -- Molecular Mechanisms of Metal-induced Carcinogenesis -- Epi-drugs Targeting RNA Dynamics in Cancer -- Oncologic Emergencies: Pathophysiology, Diagnosis, and Initial Management -- Malignancies in Inborn Errors of Immunity -- Hematopoietic Stem Cell Transplantation in Patients with Inborn Errors of Immunity and Malignancy -- Personalized Immuno-oncology with Immunodeficiency Mouse Models -- Allergy and Cancer: New Perspectives -- Depression and Cancer: the Inflammatory Bridge -- Impact of Cancer-Related Sarcopenia on Systemic Immune Status -- Surveillance of Subclinical Cardiovascular Complications in Childhood Cancer Survivors: Exercise as a Diagnostic and Therapeutic Modality.
    Abstract: Cancer is a major public health concern and one of the leading causes of death. There is no simple solution for this complex disease, therefore interdisciplinary approaches might help to find solutions to many unanswered questions and challenges about cancer. The rapid flow of interdisciplinary research in cancer during recent years has increased our understanding of the nature of cancers. Such interdisciplinary approaches could be helpful for both the diagnosis and the development of more effective therapeutic strategies. The “Interdisciplinary Cancer Research” series publishes comprehensive volumes on different cancers and presents the most updated and peer-reviewed articles on human cancers. Over the past decade, increased cancer research has greatly improved our understanding of the nature of cancerous cells which has led to the development of more effective therapeutic strategies to treat cancers. This interdisciplinary series is of special value to researchers and practitioners working on cell biology, immunology, hematology, biochemistry, genetics, oncology and related fields. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN).
    Type of Medium: Online Resource
    Pages: XI, 611 p. 31 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031324581
    Series Statement: Interdisciplinary Cancer Research, 1
    DDC: 571.978
    Language: English
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  • 10
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Sustainability. ; Environmental monitoring. ; Geography. ; Geographical Information System. ; Sustainability. ; Environmental Monitoring. ; Regional Geography.
    Description / Table of Contents: Introduction -- Remote Sensing Data Preprocessing Technology -- Remote Sensing Extraction Technology of Urban Vegetation Information -- Measurement Technology of Two-Dimensional Urban Green Space -- Measurement Technology of Three-Dimensional Urban Green Space -- Construction Technology of Multi-Scale Perception Model of Urban Green Space -- Evaluation Technology of Remote Sensing in Urban Green Space.
    Abstract: This book presents a systematic study of urban green space remote sensing from multi-dimensional and multi-scale technologies. On the basis of introducing the connotation, science and application value of urban green space, this book focuses on the two-dimensional and three-dimensional information extraction technology of urban vegetation, two-dimensional and three-dimensional measurement technology of urban green space and multi-scale perception technology and discusses the remote sensing evaluation method of urban green space. By exploring the technical advantages of ‘satellite remote sensing + aerial remote sensing + near-ground remote sensing’, urban green space remote sensing promotes the development of urban vegetation research from two-dimensional to three-dimensional observation, so that the quantity, quality and human perception of urban vegetation can be measured. In each chapter, an individual technology/method is introduced, and several cases are cited to demonstrate its practical application. This book offers a valuable reference guide for practitioners in urban planning, landscape greening, environmental protection and urban management, as well as teachers and graduate students engaged in urban remote sensing research.
    Type of Medium: Online Resource
    Pages: XVI, 240 p. 164 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819907038
    DDC: 910.285
    Language: English
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  • 11
    Keywords: Geographic information systems. ; Human geography. ; Environmental management. ; Geographical Information System. ; Human Geography. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Interdisciplinarity, GIScience, and Socio-environmental Research in Latin America -- Chapter 2. Using Spatial Time-series and Field Data to Understand Cultural Drivers of Land Change: Connecting Land Conflict and Land Change in Eastern Amazonia -- Chapter 3. Crossing Boundaries: Transboundary Geographic Information in the Amazon Borderlands of Peru and Brazil -- Chapter 4. Territorial Implications of Economic Diversification in the Waorani Ancestral Lands -- Chapter 5. New Insights on Water Quality and Land Use Dynamics in the Napo Region of Western Amazonia -- Chapter 6. From Mapping to Guiding: An Emergent Framework for the Multiple Uses of Remote Sensing and GIScience in Socio-Environmental Research in the Peruvian Andes -- Chapter 7. The Use of Remote Sensing in Air Pollution Control and Public Health -- Chapter 8. Human-environmental Interactions and their Impacts on Temperate Forests in the Exploradores Valley in Western Patagonia -- Chapter 9. El Chaltén, Argentine Patagonia: A successful Combination of Conservation and Tourism? -- Chapter 10. GIS Approaches to Environmental Justice in Mexico’s Oil and Gas Production Zones with Implications for Latin America -- Chapter 11. Contributions to Socio-Environmental Research through Participatory GIS in Archaeology -- Chapter 12. Comparing Volunteered Data Acquisition Methods on Informal Settlements in Mexico City and São Paulo: a Citizen Participation Ladder for VGI -- Chapter 13. CHALLENGES AND OPPORTUNITIES Interdisciplinary GIScience Research on Human-environment Dynamics in Latin America.
    Abstract: This contributed volume presents relevant examples of socio-environmental research that highlight the challenges and opportunities of using geotechnologies in interdisciplinary settings across the vast, culturally, and environmentally mega-diverse region known as Latin America. While remote sensing has been mostly used for mapping and monitoring physical features, geographic information systems open up opportunities for the integration of socio-economic and environmental data collected through individual and community-based surveys, in-situ measurements, and other participatory research techniques to offer additional analytically grounded power when evaluating socio-environmental processes that shape Latin American landscapes. The topics addressed in this book include deforestation and land degradation, borderlands dynamics, agriculture and agroecological systems, environmental conservation and development, public health, tourism, environmental justice, archeology, volunteered geography and urban planning, among others. The book is intended for academics, graduate and undergraduate classrooms, and general audiences with interest in Latin America and the socio-environmental issues that threaten the sustainability of the region and local communities. The book will also appeal to practitioners, managers, and policy makers interested in the application of geo-technologies and field-based research to address complex socio-environmental problems in the Global South. .
    Type of Medium: Online Resource
    Pages: XIX, 294 p. 78 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031226809
    Series Statement: The Latin American Studies Book Series,
    DDC: 910.285
    Language: English
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  • 12
    Keywords: Geographic information systems. ; Environmental geography. ; Physical geography. ; Environmental management. ; Geographical Information System. ; Integrated Geography. ; Earth System Sciences. ; Environmental Management.
    Description / Table of Contents: Development of Reconfigurable Low-Power Measuring IoT Device for Detecting Common Radioactive Elements for Earth and Space Applications -- RECO-FSCA: Reconfigurable Low-Power Implementation of Fprime-Software for CubeSats Applications -- Autonomous Payload Imaging System for Remote Sensing Applications -- Plasma Space Debris Removal System – NIRCSAT-X -- Heat Energy Storage Module for Thermal Management of Small Satellites In Low Earth Orbit Thermal Conditions.
    Abstract: This book covers various aspects of remote sensing and geographic information systems, from the perspective of earth and environmental sciences. The theme of applications of remote sensing and geographic information systems for the purposes of sustainable development highlights the innovative usage of space imaged spectral data in soil characterization. This book merges the selected contributions to the First International Conference of Remote Sensing and Space Sciences Applications (Egypt 2022) aiming to promote the latest findings on the development of Space Technologies and Applications.
    Type of Medium: Online Resource
    Pages: XIV, 441 p. 168 illus., 157 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031404474
    Series Statement: Springer Proceedings in Earth and Environmental Sciences,
    DDC: 910.285
    Language: English
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  • 13
    Keywords: Geographic information systems. ; Environmental health. ; Public health. ; Sustainability. ; Geographical Information System. ; Environmental Health. ; Public Health. ; Sustainability.
    Description / Table of Contents: Topic 1. Environmental Quality Monitoring -- Chap1: Applications of Remote Sensing for Air Pollution Monitoring in Thailand: An Early Warning for Public Health -- Chap2: A novel evaluation of air pollution impact from stationary emission sources to ambient air quality via time-series Granger causality -- Chap3: Groundwater Recharge, Monitoring and Finding Suitable Areas for Groundwater Recharge in Northeast Thailand -- Topic 2. Environmental Changes and Health -- Chap4: Health benefits of air pollution reduction during the COVID-19 lockdown period in Thailand using a machine learning algorithm -- Chap5: Satellite-Derived Vegetation Indices as A Criterion for Assessing Green Exposure that is Related to Human Health Burdens -- Chap6: Five common myths about land use change and infectious disease -- Topic 3. Data and Methodological Issues for Health Studies -- Chap7: Geospatial Environmental Data for Planetary Health Applications -- Chap8: Delineating zones of disease diffusion from the amenity-sharing network in Peninsular Malaysia -- Chap9: Approaches for spatial and temporal-spatial clustering analysis in avian influenza outbreaks -- Chap10: Detecting urban form using remote sensing: spatiotemporal research gaps for sustainable environment and human health.
    Abstract: Planetary health involves complex spatial–temporal interactions among agents, hosts, and earth environment. Due to rapid technical development of geomatics, including geographic information systems (GIS) and remote sensing (RS) in the era of big data analytics, therefore, earth data analytics has become one of the important approaches for monitoring earth surface process and measuring of the effects of environment changes on all humans and other living organisms on earth. Various methods in earth data analytics, including spatial–temporal statistics, spatial evolutionary algorithms, remote sensing image analysis, wireless geo-sensors, and location-based analytics, are an emerging discipline in understanding complex interactions in planetary health. This edited book provides a broad focus on methodological theories of earth data analytics and their applications to measuring the process of planetary health, with the goal to build scientific understanding on how geospatial analytics can provide valuable insights in measuring environmental risks in Southeast Asian regions. It is collection of selected papers covering both theoretical and empirical studies focusing on topics relevant to spatial perspectives on planetary health and environmental exposure studies. The book is written for senior undergraduates, graduate students, lecturers, and researchers in applications of geospatial technologies for public health and environmental studies.
    Type of Medium: Online Resource
    Pages: IX, 217 p. 60 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811987656
    Series Statement: Atmosphere, Earth, Ocean & Space,
    DDC: 910.285
    Language: English
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  • 14
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Natural disasters. ; Environmental sciences Social aspects. ; Atmospheric science. ; Geographical Information System. ; Natural Hazards. ; Environmental Social Sciences. ; Atmospheric Science.
    Description / Table of Contents: Overview Of Geospatial Science And Technology -- Geospatial Appraisal Of Vegetation Health And Air Quality Of Delhi During Pre And Post Lockdown Phase Through Multi-Criteria Decision Model -- Pandemic Effect Of Covid-19: Identification, Present Scenario And Preventive Measures -- Impact Of Lockdown (Covid-19) On Air Pollution In India -- Impact Of Covid-19 Pandemic On Environmental Awareness: A Case Study Of Hyderabad City -- Examination Of Radiation Distribution And Its Relation With Stress Degree Day Index In Some Crops Of Yamne River Catchment In Arunachal Pradesh During Pre And Post Covid Times -- Covid 19 And Its Impact On Urban Health Care System -- Impact Of Covid-19 Pandemic On Education Sector Of Kashmir Valley Its Challenges And Future Prospects -- A Study On Socio-Economic Impact Of Covid 19 Pandemic On Tour Operators Of Vishakhapatnam City, Andhra Pradesh -- A Study On Problems Faced By The Street Vendors In Hyderabad City Post Covid-19 Pandemic.
    Abstract: This book identifies, evaluates and reports the impacts of the COVID-19 pandemic on the physical, biological and socioeconomic environment, using the science and technology of geoinformatics. It encourages the environmental considerations in the future city and policy planning and decision-making. For example, according to the World Health Organization, 80% of people living in cities are exposed to polluted air that exceeds healthy levels. City planners have applied the developing concepts of sustainability to modern debates over how cities and regions should be reviewed, regenerated and reformed since the introduction of the concept in developmental science. During the COVID-19 pandemic, a remarkable drop in air pollution has been observed in India and other countries, which has accelerated the shift to green and sustainable development. Geoinformatics can provide solutions and resources for local, sustainable activities in education, health, sustainable agriculture, resource management and related fields. This book serves researchers in a variety of areas, including hazards, land surveys, remote sensing, cartography, geophysics, geology, natural resources, environment and geography.
    Type of Medium: Online Resource
    Pages: X, 155 p. 68 illus., 67 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819919345
    Series Statement: Advances in Geographical and Environmental Sciences,
    DDC: 910.285
    Language: English
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  • 15
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Stem cells. ; Cytology. ; Developmental biology. ; Cancer Stem Cells. ; Cell Biology. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: Assays for monitoring autophagy in stem cells -- Autophagy in Stem Cell Maintenance and Differentiation -- Autophagy in Embryonic stem cells and Neural stem cells -- Autophagy in Germline Stem Cells -- The role of autophagy in the regulation of hematopoietic stem cells -- Autophagy in Muscle Stem Cells -- Autophagy in Intestinal Stem Cells -- The autophagy lysosomal pathway: friend or foe in adult neural stem cells? -- Autophagy in Mesenchymal Stem Cell-based therapy -- Autophagic control of stem cells differentiation into osteogenic lineage- Implications in bone disorders -- Autophagy in Cancer Metastasis.
    Abstract: This book covers a wide range of topics that illustrate the various functions of autophagy in stem cells and offers insights on the mechanisms by which autophagy can regulate stem-cell self-renewal and facilitate specific differentiation programs. Stem cells are unique cells present in most multicellular animals and are essential for their survival. They have two unique properties: the ability to self-renew and the ability to differentiate into one or more cell types. These characteristics of stem cells have found immense therapeutic potential in regenerative medicine. Autophagy is a crucial membrane trafficking pathway that is essential for maintaining cellular homeostasis that involves sequestration of non-functional proteins, protein aggregates and damaged organelles in double-membraned vesicles called autophagosomes, which are subsequently targeted to the lysosome for degradation. The primary aim of this book is to provide knowledge of recent developments in our understanding of the role of autophagy in stem cells, including germline stem cells. Autophagy is considered a promising target for many diseases. Significant efforts are being developed to identify specific modulators of autophagy, which will aid in designing combinatorial therapeutic strategies that will allow significant improvements in regenerative medicine.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 41 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031173622
    Series Statement: Stem Cell Biology and Regenerative Medicine, 73
    DDC: 571.978
    Language: English
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  • 16
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Biology Technique. ; Stem cells. ; Cancer Biology. ; Biological Techniques. ; Cancer Stem Cells. ; Stem Cell Biology.
    Description / Table of Contents: 1. On the origin of cancer -- 2. Culture of Cells: Basic Principles -- 3. Stem cell culture from embryos -- 4. Reprogramming of normal cells -- 5. Maintenance of human Pluripotent Stem Cells -- 6. Identification of cancer stem cells by different molecular markers -- 7. Enrichment of Cancer Stem Cell from malignant tumor -- 8. Isolation of single clonal cell from primary cultured cells and establishment of a cancer stem cell line -- 9. Artificial Generation of Cancer Stem Cells from Normal Stem Cells -- 10. Quick method to assess non-mutagenic carcinogens with iPS cells -- 11. Self-renewal potential of caner stem cells -- 12. Differentiation potential of cancer stem cells in vitro -- 13. Tumor Angiogenesis by cancer stem cells in vivo -- 14. Invasion and Metastatic potential of cancer stem cells in vitro -- 15. Metastatic potential of cancer stem cells In Vivo- 16. Anchorage-independent cell growth assay for Cancer Stem Cells: Tumorigenic assay in vitro -- 17. Tumorigenic potential of cancer stem cells in vivo -- 18. Development of immunoliposomes using monoclonal antibodies targeting cancer stem cells -- 19. In-vitro evaluation of anti-cancer stem cell drugs -- 20. In vitro Tumoroid Model Using Cancer Stem Cells.
    Abstract: This book describes the use of stem cells and cancer stem cell generation in the inflammatory microenvironment (cancer-inducing niche) using induced pluripotent stem cells. It provides step-by-step techniques and manuals for studying stem cell and cancer stem cell generation with different applications in cancer research. The development of induced pluripotent stem cells has provided a new approach to studying cancer initiation by producing cancer stem cells without introducing mutations or foreign genes. The book features the research of the authors’ group, which was the first to generate cancer stem cells from stem cells in the presence of inflammatory conditions. The 20 chapters if this book cover topics such as generating pluripotent stem cells, converting normal stem cells to cancer stem cells, enriching, isolating and evaluating cancer stem cells. Methods for evaluating the characteristics of cancer stem cells and possible therapies against them are also discussed. The book provides easy-to-follow protocols that help researchers in the study of cancer stem cells. Illustrations help readers understand how the method of cancer stem cell generation can be applied as an essential method for assessing the carcinogenic potential of various non-mutagenic compounds. It will be a useful resource for graduate students, researchers, technicians, and physicians working in academic, hospital, and pharmaceutical settings. .
    Type of Medium: Online Resource
    Pages: XVII, 243 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819913312
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Cancer Treatment. ; Tumors Immunological aspects. ; Cancers. ; Cancer Therapy. ; Cancer Biology. ; Tumour Immunology.
    Description / Table of Contents: Chapter 1. Hypoxia and its Biological Implications for Cancer Therapy -- Chapter 2. Hypoxia's function in cancer -- Chapter 3. Role of Hypoxia and Reactive Oxygen Species in cancer biology -- Chapter 4. Hypoxic tumor microenvironment: driver for cancer progression -- Chapter 5. Hypoxia and Senescence: Role of Oxygen in Modulation of Tumor Suppression -- Chapter 6. Hypoxia Regulated Gene Expression and Metastasis -- Chapter 7. piRNA based cancer therapy in hypoxic tumor -- Chapter 8. MicroRNA Signatures of Tumor Hypoxia -- Chapter 9. Hypoxia and the Metastatic Cascade -- Chapter 10. Hypoxia and Extra Cellular Matrix-major drivers of tumor Metastasis -- Chapter 11. Role of Hypoxia in Cancer Therapy – Introduction -- Chapter 12. Hypoxic regulation of telomerase gene expression in cancer -- Chapter 13. CRISPR/Cas9-editing-based modeling of tumor hypoxia -- Chapter 14. Tumor-on-a-chip: Microfluidic models for Hypoxic tumor microenvironment -- Chapter 15. Imaging the Hypoxic Tumor microenvironment in cancer models -- Chapter 16. Hypoxia-targeting drugs as new cancer chemotherapy agents Hypoxia-targeting drugs as new cancer chemotherapy agents - Molecular Insights -- Chapter 17. Identification of Hypoxia targeting drugs in the tumor microenvironment and prodrug Strategies for Targeting Tumor Hypoxia -- Chapter 18. Hypoxia Induced Apoptosis in Cancer Development -- Chapter 19. Hypoxia in drug resistance and radioresistance.
    Abstract: This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.
    Type of Medium: Online Resource
    Pages: XV, 447 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903139
    DDC: 571.978
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Cancer Animal models. ; Cancer Treatment. ; Cancer Genetic aspects. ; Cancer Biology. ; Cancer Models. ; Cancer Therapy. ; Cancer Genetics and Genomics. ; Cancer Microenvironment.
    Description / Table of Contents: Chapter 1: Cancer as a Disease of Cell Proliferation -- Chapter 2: Genetic and Chromosomal Instability -- Chapter 3: Cancer as a Disease of Defective Cell Cycle Checkpoint Function -- Chapter 4: The DNA Damage Checkpoint -- Chapter 5: Dynamics of the Spindle Assembly Checkpoint -- Chapter 6: Cancer as a Disease of Complexity: The Dynamics of Drug Resistance -- Chapter 7: Chronic Myeloid Leukaemia: a One-Hit Malignancy -- Chapter 8: Chronic Myelomonocytic Leukaemia: a Three-Hit Malignancy -- Chapter 9: The Cancer Stem Cell and Tumour Progression -- Chapter 10: Evading the antitumour immune response -- Chapter 11: Implications of Evolutionary Dynamics for Cancer Treatment and Prevention -- Chapter 12: In science, all conclusions are provisional.
    Abstract: Advances in cancer genomics are transforming our understanding of cancer, and have profound implications for its prevention, diagnosis, and treatment. Evolutionary dynamics suggests that as few as two mutations can cause transformation of normal cells into cancer stem cells. A process of Darwinian selection, involving a further three or more mutations, taking place over a period of years, can then result in progression to a life-threatening tumour. In many cases the immune response can recognise and eliminate the mutant cells, but most advanced tumours have mutations that activate immune checkpoints and enable the tumour to hide from the immune system. For the most hard-to-treat tumours, future progress will require molecular diagnostics to detect cancer-causing mutations in healthy subjects, and new drugs or vaccines that prevent the progression process. Chapters of this book deal with the signalling pathways that control cell division, and changes in these pathways in cancer cells. Three cell cycle checkpoints that are often mutated in cancer are analysed in detail. A discussion of chronic myeloid leukaemia illustrates the role of reactive oxygen species in driving progression from a chronic to an acute condition. A single drug that suppresses reactive oxygen can prevent disease progression and turn an otherwise deadly disease into a condition that can be managed to enable many years of normal life. Another chapter discusses chronic myelomonocytic leukaemia, a disease that involves both genetic and epigenetic change. Tumour progression is discussed as a multi-stage process in which cancer stem cells evolve into genetically unstable, invasive, metastatic, drug-resistant growths. Each of these stages can act as targets for drugs or immunomodulators, but the future of cancer treatment lies in understanding tumour dynamics, and arresting malignancy at the earliest possible stage. Evolutionary dynamics is a primarily mathematical technique, but the target readership will be tumour biologists, clinicians, and drug developers. Computational detail is provided in an online supplement, but the main text emphasises the implications of the dynamics for an understanding of tumour biology and does not require mathematical expertise.
    Type of Medium: Online Resource
    Pages: XIV, 269 p. 96 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031325731
    DDC: 571.978
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Cancer Genetic aspects. ; Cancer Treatment. ; Cancer Biology. ; Cancer Genetics and Genomics. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1. Breast cancer -- Chapter 1.1. Epidemiology -- Chapter 1.2. Etiology -- Chapter 1.3. Types of breast cancer -- Chapter 1.4. Signs and symptoms -- Chapter 1.5. Stages -- Chapter 1.6. Diagnosis -- Chapter 1.7. Treatment -- Chapter 2. Genetic landscape of breast carcinogenesis -- Chapter 2.1. Hormone receptor positive breast cancer -- Chapter 2.1. Her2 positive breast cancer -- Chapter 2.2. Triple negative breast cancer -- Chapter 3. Epigenetic involvement in breast carcinogenesis -- Chapter 3.1. Histone modification -- Chapter 3.2. DNA methylation -- Chapter 3.3. miRNA -- Chapter 4. Breast cancer control -- Chapter 4.1. Conventional drugs targeting Genetic and Epigenetics in Breast cancer -- Chapter 4.2. Pitfalls of conventional therapy -- Chapter 4.3. Natural remediation -- Chapter 5. Conclusion.
    Abstract: This book discusses the contribution of genetics and epigenetics alterations in the initiation, development, and recurrence of breast cancer. It also reviews the potential of translating the epigenetic alterations into diagnosis, prognosis, and breast cancer therapy. The initial chapters explore the epigenetics, etiology, and conventional treatment strategies for breast cancer. The subsequent chapters discuss the genetic landscape and cover three main epigenetic modulation mechanisms; histone modification, DNA methylation, and miRNA silencing. Further, the book explores the potential of epigenetic drugs in treating breast cancer. Lastly, it covers the phytochemicals targeting epigenetic modulators in breast cancer treatment. This book is an essential source for researchers and practitioners interested in exploring the potential of epigenetics modulators in breast cancer treatment.
    Type of Medium: Online Resource
    Pages: X, 87 p. 13 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811999253
    DDC: 571.978
    Language: English
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  • 20
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Stem cells. ; Cancer Treatment. ; Cancer Genetic aspects. ; Cancer Stem Cells. ; Cancer Therapy. ; Cancer Biology. ; Cancer Genetics and Genomics.
    Description / Table of Contents: 1. Introduction and perspective in carcinogenesis -- 2. Origin and Development of Cancer Stem Cells -- 3. Detection and Isolation of Cancer Stem Cells -- 4. The genetic and epigenetic landscape of cancer stem cells -- 5. Metabolism of Cancer Stem Cell -- 6. Plasticity of Cancer Stem Cell -- 7. Cancer Stem Cells in Cancer Initiation and Progression -- 8. Cancer Stem Cells and Metastasis -- 9. Roles of Cancer Stem Cells in Therapy resistance and Disease Recurrence -- 10. Novel therapeutics targeting cancer stem cell surface markers -- 11. Therapeutics targeting cancer stem cells signalling pathways -- 12. Cancer stem cells therapeutics delivery and EPR effect -- 13. Immunotherapy against cancer stem cells -- 14. Engineering nanobody targeting cancer stem cells -- 15. Biological barriers for drug delivery to cancer stem cells -- 16. Cancer Stem Cell Markers in Haematological Malignancies -- 17. Diagnostic and Prognostic Significance of Cancer Stem Cells Surface Markers -- 18. Diagnostic and prognostic implications of cancer stem cells transcription factors -- 19. Diagnostic and prognostic significance of intracellular markers of CSCs in patients with cancers. .
    Abstract: This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the maintenance and survival of CSCs. It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity of CSCs in cancer biology. Further, it also presents the implications of CSCs on the origin of tumor heterogeneity and on heterogeneity of the therapeutic response. Towards the end, this book highlights the different immunotherapeutic approaches targeting CSCs with the potential of strongly improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications.
    Type of Medium: Online Resource
    Pages: XVI, 372 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819931859
    DDC: 571.978
    Language: English
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  • 21
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Tumors Immunological aspects. ; Therapeutics. ; Cancers. ; Tumour Immunology. ; Therapeutics.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Expression pattern of Chemokines in Cancer -- Chapter 3_Implications of Cytokine-Chemokine Heterogenity in Cancer -- Chapter 4_Cytokine and chemokines networks in cancer stemness -- Chapter 5_Cytokine and chemokines networks in angiogeneis -- Chapter 6_Role of Cytokine-Chemokine cascades in Epithelial to Mesenchymal Transition -- Chapter 7_Role of Chemokines in establishment of Metastatic Niche -- Chapter 8_CXCL12-CXCR4 axis in Metastasis -- Chapter 9_Chemokine and cytokine networks in the tumor microenvironment -- Chapter 10_CXCL9, CXCL10, CXCL11/CXCR3 axis and Immune Activation -- Chapter 11_CXCL8-CXCR1/2 axis in cancer and inflammatory diseases -- Chapter 12_Cytokine and Chemokine Networks in Therapeutic Resistance -- Chapter 13_Prognostic and diagnostic significance of Chemokines and cytokines in cancer -- Chapter 14_Therapeutic implications of Chemokines and cytokines networks in cancer -- Chapter 15_Chemokines in cancer therapy.
    Abstract: Cytokine and Chemokine Networks in Cancer" provides a comprehensive exploration of the roles of cytokines and chemokines in cancer biology. It offers valuable insights into their diagnostic, prognostic, and therapeutic implications, making it a valuable resource for researchers, clinicians, and students interested in the field of cancer immunology and therapy. This book illustrates the importance and significance of the cytokine and chemokine signaling networks in tumor development and progression. It describes the complex networks mediated by cytokine and chemokine receptors promoting tumor cell proliferation, site-directed metastasis, and activation of angiogenic switch in tumor cells. The books also shed light on the heterogeneity of cytokines and chemokine in solid malignancies and their impact on tumor progression and therapeutic outcomes. The chapters provide current information about the types of cytokine-chemokine interactions in promoting cancer stem cell-like characteristics, epithelial to mesenchymal transition, and modulation of the tumor microenvironment. The significance of the complex interactions in cancer biology in the light of therapeutic resistance is also highlighted. The chapters also describe recent advancements in the therapeutic potential of targeting the pro-tumor cytokine and chemokine networks and limiting tumor cell metastasis. Finally, the book also provides a comprehensive yet representative description of a large number of challenges associated with targeting these vital chemokine-cytokine networks. Given its content, the book provides valuable information for researchers in the field of cancer biology and molecular medicine.
    Type of Medium: Online Resource
    Pages: XVII, 440 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819946570
    DDC: 571.978
    Language: English
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  • 22
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Metabolism. ; Cancer Treatment. ; Biochemistry. ; Oxidation-reduction reaction. ; Cancer Metabolism. ; Cancer Therapy. ; Redox Biology.
    Description / Table of Contents: 1. ROS, redox regulation and signaling in cancer cells -- 2. ROS and redox regulation/signaling and metabolism in cancer stem cells -- 3. . ROS/Redox regulation with dietary phytochemicals and role in anticancer activity -- 4. ROS/Redox signaling and apoptosis/necroptosis/autophagy in cancer -- 5. Cancer Metastasis, ROS/redox signaling and PCD resistance/redox metabolism -- 6. Immune system, redox signaling and cancer immunity -- 7. P53, ROS- redox regulation signaling, metabolic reprogramming and autophagy in cancer -- 8. Cell cycle, DNA damage-repair systems and impact of redox regulation in cancer -- 9. ROS, redox regulation and anticancer therapy -- 10. Perspectives in ROS/redox regulation cancer therapy.
    Abstract: This book aims to provide an association of the major redox-sensitive pathways and networks involved in cancer. The initial chapter of the book discusses basic information about oxidative stress, its generation, and regulation (redox regulation or redox homeostasis) via cell signaling in normal and cancer cells. The book also explores antioxidants and metabolic events in cancer cells compared to normal cells. It further covers the application of nanoparticles in redox regulation in cancer cells. The role of redox regulation in cancer therapy, its influence, and its involvement in programmed cell death (PCD), metastasis, immune system, p53, and cell cycle/DNA damage repair pathways have been discussed in separate chapters. It further reviews the importance of dietary phytochemicals in redox regulation in normal and cancer pathophysiology. Towards the end, the book focuses on the role of redox balance, especially in ROS-dependent cellular processes in cancer stem cells.
    Type of Medium: Online Resource
    Pages: XI, 431 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819973422
    DDC: 571.978
    Language: English
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  • 23
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Cartography. ; Software engineering. ; Application software. ; Geographical Information System. ; Cartography. ; Software Engineering. ; Computer and Information Systems Applications.
    Description / Table of Contents: Chapter 1: Introduction to Participatory Mapping Software and Evaluation -- Chapter 2: Collector for ArcGIS -- Chapter 3: Field Papers -- Chapter 4: GeoODK -- Chapter 5: Maptionnaire -- Chapter 6: KoBoToolbox -- Chapter 7: SeaSketch -- Chapter 8: Sapelli -- Chapter 9: Survey123 -- Chapter 10: Ushahidi -- Chapter 11: Mapeo -- Chapter 12: Terrastories -- Chapter 13: Portable OpenStreetMap -- Chapter 14: MapBox -- Chapter 15: Trends and Conclusions.
    Abstract: This volume provides a framework for evaluating geospatial software for participatory mapping. The evaluation is based on ten key indicators: ethics, cost, technical level, inclusiveness, data accuracy, data privacy, analytical capacity, visualization capacity, openness, and accessibility (i.e., mobile friendly or offline capabilities). Each application is evaluated by a user and cross analyzed with specific case studies of the software’s real-world application. This framework does not discriminate against assessing volunteered geographic information (VGI) applications, as a form of participatory mapping, in circumstances that its application is spearheaded by underrepresented groups with the intent to empower and spark political or behavioral change within formal and informal institutions. Each chapter follows a strict template to ensure that the information within the volume can be updated periodically to match the ever-changing technological environment. The book covers twelve different mapping applications with the goal of creating a comparative evaluation framework that can be easily interpreted by convening institutions and novice users. This will also help identify gaps in software for participatory mapping which will help to inform application development in the future and updates to current geospatial software.
    Type of Medium: Online Resource
    Pages: XXV, 265 p. 69 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031195945
    DDC: 910.285
    Language: English
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  • 24
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Human ecology Study and teaching. ; Environment. ; Geographical Information System. ; Environmental Studies. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1. Natural heritage sites and space observation -- Chapter 2. Space monitoring technology and method of natural heritage sites -- Chapter 3. Technology and method of fine information extraction of animal habitat elements -- Chapter 4. Analysis of changes of key environmental parameters of land surface characteristics of giant panda habitat -- Chapter 5. Spatial observation and assessment of ecological environment change of giant panda habitat -- Chapter 6. The evaluation model of long-term monitoring and restoration of ecological environment by remote sensing after earthquake -- Chapter 7. Fine-Scale Evaluation of Giant Panda Habitats and Countermeasures against the Future Impacts of Climate Change -- Chapter 8. Suggestions for sustainable development of giant panda habitat.
    Abstract: This book evaluates the past, present, and future habitat suitability of giant pandas based on spatial observation technology involving optical remote sensing, microwave remote sensing, and LiDAR to discover the mysterious ecological environment of giant panda habitat. Considering the problems faced by the world natural heritage site protection, it takes the world natural heritage site “Sichuan Giant Panda Sanctuaries – Wolong, Mt Siguniang and Jiajin Mountains” as the research area, exemplifies systematically the various techniques and methodologies of spatial information technology for monitoring, evaluation, and prediction of rare and endangered species habitats, and provides scientific suggestions for sustainable development of giant panda habitat based on a series of comprehensive case analysis at Wolong national nature reserve and Ya'an prefecture, Sichuan province, China. The book serves both as a textbook in the field of natural heritage protection, remote sensing, and GIS application, as well as a reference for managing natural heritage sites.
    Type of Medium: Online Resource
    Pages: XVII, 378 p. 167 illus., 106 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811987946
    DDC: 910.285
    Language: English
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  • 25
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Surveying. ; Cartography. ; Geotechnical engineering. ; Geographical Information System. ; Surveying. ; Cartography. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Introduction -- Structural state surveying for transportation infrastructure -- Dynamic surveying in autonomous driving -- Indoor and underground space measurement -- UAV 3D measurement -- Coastal zone survey -- Outlook. .
    Abstract: Driven by the increasingly expanding needs of infrastructure construction, operation and maintenance, as well as the rapid developments of intelligent sensing and information technology, precise engineering surveying has been transformed from static, discrete, and manual into dynamic, continuous, and intelligent ways. This transformation leads to an advanced multidisciplinary field, dynamic and precise engineering surveying, on which the author has worked for over two decades. This book systematically summarizes the fundamentals, methods, and applications in dynamic and precise engineering surveying. The contents mainly include two parts: the first part introduces principles and methods of dynamic and precise engineering surveying; the second part presents representative applications in which innovative methods and advanced equipment are applied in the construction, operation and maintenance of mega and complex infrastructures. Readers engaged in surveying and mapping, civil engineering, water conservancy engineering, railway engineering, electronic information, and computer science, including undergraduates, graduates, researchers and engineers, will find it an informative reference.
    Type of Medium: Online Resource
    Pages: XXVIII, 498 p. 394 illus., 352 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819959426
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Environmental geography. ; Sustainability. ; Geographical Information System. ; Integrated Geography. ; Sustainability.
    Description / Table of Contents: Chapter1. Flood Susceptibility Mapping Using a Frequency Ratio Model: A Case Study of Chai Nat Province, Thailand -- Chapter2. Influence of Hydrosphere Material Knowledge on the Attitude of High School Students in Conducting Water Conservation in Brebes Regency, Indonesia -- Chapter3. Optimizing multi-reservoir systems with the aid of genetic algorithm: Mahanadi reservoir project complex,Chhattisgarh -- Chapter4. Monitoring of Morphological Change in Lam Phachi River Using Geo-Informatics System -- Chapter5. Developing Scenario of Plastic Waste Leakage in Jakarta Hydrology Environment using Seasonal Data Condition and Socio-Economic Aspects -- Chapter6. Measurement of PM10, PM2.5, NO2, and SO2 Using Sensors -- Chapter7. Encoding Social Media Wording Indexes to Analyse PM2.5 Problem Perception -- Chapter8. Noise mapping of different zones in an urban area during Deepawali festival -- Chapter9. Digital Twins in farming with the implementation of agricultural technologies -- Chapter10. A cross-comparison between Rice Crop Monitoring System: GISTDA and International Asian Harvest mOnitoring system for Rice (INAHOR): JAXA -- Chapter11. Evaluation MODIS and Sentinel-2 data for detecting crop residue burned area -- Chapter12. Machine Learning Approach with Environmental Pollution and Geospatial Information for Mapping Poverty in Thailand -- Chapter13. Integration of Machine Learning Algorithms and Time-series Satellite images on Land Use/Land Cover Mapping with Google Earth Engine -- Chapter14. Sugarcane and Cassava Classification using Machine Learning Approach based on Multi-temporal Remote Sensing Data Analysis -- Chapter15. Google Earth Engine algorithm for Evaluating the Performance of Landsat OLI-8 and Sentinel-2 in Mangrove Monitoring -- Chapter16. Estimation of Aboveground Biomass and Carbon Stock using Remote Sensing Data for Sakaerat Environmental Research Station, Thailand -- Chapter17. Determination of Land Suitability for Oil Palm with Multi-Dimension Decision Support using Analytic Network Process (ANP) in Southern Thailand -- Chapter18. Land use change and ecosystem service variations in Huai Luang River basin, Udon Thani province, Thailand -- Chapter19. The Ability to Access Attractions for the Elderly from Public Transport in Bangkok Metropolis.
    Abstract: This volume presents the proceedings of the 2nd International Conference of Geography and Geoinformatics for Sustainable Development (ICGGS), held in Phuket, Thailand, April 7-8, 2022. The collection focuses on the importance of spatial thinking and planning by applying geography concepts and geospatial technology innovations in solving global problems such as environmental degradation, urban pollution, and climate change. The proceedings consist of case studies on wide-ranging spatial issues in developing countries, addressing challenges in mainstreaming sustainable development paradigms into their economies to improve natural resource and environmental management. One of the main goals of the volume is to share and exchange different points of view regarding global, regional, and local spatial issues and how to use geography and geoinformatics for building resilience in multiple sectors, e.g., water, ecosystems, agriculture, and health. It offers the opportunity to learn about how geospatial concepts and technologies can contribute to environmental sustainability, while advancing education and research related to geography and geoinformatics. It will be a useful resource for students and researchers to initiate research ideas related to geospatial topics in regional and local scales.
    Type of Medium: Online Resource
    Pages: VI, 260 p. 119 illus., 111 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031162176
    Series Statement: Springer Geography,
    DDC: 910.285
    Language: English
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  • 27
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Geographic information systems. ; Open source software. ; Earth sciences. ; Geographical Information System. ; Open Source. ; Earth Sciences.
    Description / Table of Contents: Chapter 1: Introduction to QGIS -- Chapter 2: Plugins -- Chapter 3: Data Acquisition -- Chapter 4: Data Preprocessing -- Chapter 5: Data Management -- Chapter 6: Data Visualization -- Chapter 7: Data Analysis -- Chapter 8: Integration of Remote Sensing Data with Other Spatial Datasets -- Chapter 9: Integration of QGIS with Google Earth Engine (GEE) -- Chapter 10: Case Studies and Examples of Earth Remote Sensing Applications Using QGIS.
    Abstract: With the rapid advancements in satellite technology, earth remote sensing has become an indispensable tool for a wide range of applications, from environmental monitoring to disaster management. However, the vast amount of data generated by these satellites can be overwhelming for many researchers and practitioners who lack the necessary skills and tools to process and analyze it. This is where QGIS comes in. QGIS is a powerful, open-source Geographic Information System (GIS) software that has been extensively used in the field of earth remote sensing. It provides a user-friendly platform for processing, analyzing, and visualizing satellite imagery, enabling users to unlock the full potential of earth remote sensing data. The purpose of this book is to help researchers and practitioners who lack the necessary skills and tools to process and analyze satellite imagery using QGIS. There are several books that cover the use of QGIS for earth remote sensing, but most of them are either too technical or too general. This book fills this gap by providing a comprehensive and user-friendly guide to using QGIS for earth remote sensing applications. It includes a range of real-world case studies that demonstrate the power and versatility of QGIS for solving complex problems in earth remote sensing. This will provide readers with practical examples of how to use QGIS for earth remote sensing and inspire them to explore new applications and possibilities. The book is intended for GIS professionals, students (undergraduate and graduate), and researchers who are interested in using QGIS for earth remote sensing applications. It will be particularly useful for those who are new to QGIS or who want to expand their knowledge of the software for remote sensing purposes.
    Type of Medium: Online Resource
    Pages: XIX, 232 p. 300 illus., 283 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031460425
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Mathematics Data processing. ; Mathematical statistics Data processing. ; Geographical Information System. ; Computational Mathematics and Numerical Analysis. ; Statistics and Computing.
    Description / Table of Contents: Introduction -- Locally Refined Splines -- Adaptive surface Fitting with Local Refinement: LR B-spline Surfaces -- A Statistical Criterion to Judge the Goodness of Fit of LR B-splines Surface Approximation -- LR B-splines for Representation of Terrain and Seabed: Data Fusion, Outliers, and Voids -- LR B-spline Surfaces and Volumes for Deformation Analysis of Terrain Data -- Conclusion.
    Abstract: This open access book provides insights into the novel Locally Refined B-spline (LR B-spline) surface format, which is suited for representing terrain and seabed data in a compact way. It provides an alternative to the well know raster and triangulated surface representations. An LR B-spline surface has an overall smooth behavior and allows the modeling of local details with only a limited growth in data volume. In regions where many data points belong to the same smooth area, LR B-splines allow a very lean representation of the shape by locally adapting the resolution of the spline space to the size and local shape variations of the region. The iterative method can be modified to improve the accuracy in particular domains of a point cloud. The use of statistical information criterion can help determining the optimal threshold, the number of iterations to perform as well as some parameters of the underlying mathematical functions (degree of the splines, parameter representation). The resulting surfaces are well suited for analysis and computing secondary information such as contour curves and minimum and maximum points. Also deformation analysis are potential applications of fitting point clouds with LR B-splines.
    Type of Medium: Online Resource
    Pages: XIX, 111 p. 61 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031169540
    Series Statement: SpringerBriefs in Earth System Sciences,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Agriculture. ; Environmental sciences Social aspects. ; Geographical Information System. ; Agriculture. ; Environmental Social Sciences.
    Description / Table of Contents: Foreword -- Preface -- Chapter 1 Introduction -- Chapter 2 Desert Locust Breeding Area and Migration Path in Africa and Asia -- Chapter 3 Monitoring of Desert Locusts in East Africa -- Chpater 4 Monitoring of Desert Locusts in West and South Asia -- Chapter 5 Remote Sensing Monitoring System of Desert Locust and its Application -- References.
    Abstract: This book deals with the topic on remote sensing monitoring of desert locust in Africa and Asia. Remote sensing monitoring of the occurrence and damage of desert locust is conducted by integrating cutting-edge technologies and methods in cross-disciplinary fields in remote sensing science, geographic information science, agronomy, plant protection, agricultural meteorology, mathematics, and computer science. The main contents include spatio-temporal data analysis and processing, desert locust breeding areas monitoring, pest migration path analysis and damage monitoring. Moreover, a desert locust remote sensing monitoring system is constructed and applied in the region of Africa and Asia countries. This book not only provides technical reference for remote sensing monitoring and application of desert locust but also serves as a research reference for scholars and graduate students engaged in agricultural remote sensing, agricultural information technology, plant protection and other related field. It will help to improve remote sensing monitoring and application of desert locust.
    Type of Medium: Online Resource
    Pages: XIV, 126 p. 116 illus., 113 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811972386
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Geography. ; Human geography. ; Environmental sciences Social aspects. ; Geographical Information System. ; Regional Geography. ; Human Geography. ; Environmental Social Sciences.
    Description / Table of Contents: Introduction of Geographic Information System -- Referencing and Coordinate Systems in GIS -- GIS Data Models -- Data Input in GIS -- Data Visualization and Output -- Spatial Data Analysis -- Non-spatial Data Management -- Applications of GIS in Urban Policy/Planning/Management -- Monitoring and Modelling of Urban Land Use Changes -- Simulating Future Urban Growth using Cellular Automata-Markov Chain Models -- Identification of Potential Sites for Housing Development Using GIS Based Multi-Criteria Evaluation Technique -- Urban Green Space Analysis and Potential Site Selection for Green Space Expansion -- A Multi-Criteria Decision Making for Alternative Landfill Site Selections Using Fuzzy TOPSIS Approach -- Urban Flood Susceptibility Modelling of Srinagar using Novel Fuzzy Multi-Layer Perceptron Neural Network (Fuzzy MLPNN) -- Assessment, Mapping and prediction of Urban Heat Island. .
    Abstract: Geographic Information Systems (GIS) play a pivotal role in the field of urban planning and management and provide better solutions for numerous urban problems. With GIS, one has the ability to better understand existing requirements of a city and its design to fulfill those needs. This book contributes to developing scientific knowledge based on geospatial technologies among planners, researchers, scientists, professionals, students, and laymen and providing them with better understanding for urban planning and management at various levels. The book manifests the importance of GIS in better understanding of current urban challenges and provides new insights on how to apply GIS in urban planning. It also encourages the various stakeholders of society to participate in the decision-making process and assists planners and authorities to formulate suitable plans for sustainable urban growth of a region. The book is divided into two parts. The first part describes the fundamental concepts of GIS and also deals with the advanced techniques of spatial planning. The second part addresses real-world case studies using various applications of GIS. The case studies include urban land-use changes, simulation of future urban growth, urban heat island, alternate landfill site selection and urban flood susceptibility mapping, among others. This book shows how to integrate GIS with remote sensing, geostatistics, artificial intelligence-machine learning techniques, and other cutting-edge technologies. Readers find this book to be an invaluable resource for understanding and solving problems relating to sustainable urban planning and management.
    Type of Medium: Online Resource
    Pages: XVII, 252 p. 115 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978555
    Series Statement: Advances in Geographical and Environmental Sciences,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Geographic information systems. ; Real estate management. ; Geographical Information System. ; Real Estate Management.
    Description / Table of Contents: Chapter 1. General State of the Real Estate Market in Ukraine -- Chapter 2. Real Estate Market. Trends and Developments -- Chapter 3. Practical Aspects. Development of a Method of Modeling the most attractive location of a Real Estate object -- Chapter 4. Determination of the Optimal location of the Real Estate object -- Chapter 5. Factors of Influence on the Real Estate Market -- Chapter 6. Prospects for the Development of the Real Estate Market in Ukraine -- Chapter 7. The Situation on the Real Estate Market because of Russia's War against Ukraine. .
    Abstract: This book shows examples of basic approaches in real estate market analysis. Of value is the method of modeling the most attractive location of real estate, which is illustrated by a specific example. The authors give examples of real estate market research using GIS. The book analyzes the trends and prospects of real estate market development both in the pre-war and in the post-war period in Ukraine. It provides factors, trends, and development of the real estate market-directed investments. This book is useful to investors, real estate appraisers, real estate market researchers, GIS specialists, developers, researchers, graduate students, and students.
    Type of Medium: Online Resource
    Pages: VIII, 146 p. 81 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031312489
    Series Statement: SpringerBriefs in Geography,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Cartography. ; Urban ecology (Biology). ; Human geography. ; Geographical Information System. ; Cartography. ; Urban Ecology. ; Human Geography.
    Description / Table of Contents: Data And Urban Poverty: Detecting And Characterising Slums And Deprived Urban Areas In Low-And Middle-Income Countries -- Investigation Of Ecological Sustainability Through The Landscape Approach Of Geospatial Technology: Study From New Town Project In Eastern India -- Advanced Remote Sensing For Sustainable Decent Housing For The Economically Challenged Urban Households -- Impact Of Uncontrolled Tourism Development On Landscape Ecology Of Purba Medinipur Coastal Region, West Bengal: A 4-C Framework And Swoc Analysis -- Impact Of Urban Heat Island: A Local-Level Urban Climate Phenomenon On Urban Ecology And Human Health -- Identification Of Environmental Epidemiology Through Advanced Remote Sensing Based On Ndvi -- Assessment Of Land Utilization Pattern And Their Relationship With Surface Temperature And Vegetation In Sikkim, India -- Monitoring Land Use And Land Cover Change Over Bhiwani District Using Google Earth Engine -- Image And Perception Of Royal Heritage And Eco-Space Of The Medium Towns In India: Reflection From Burdwan Royal Heritage Site -- Governance And Floodplain Extent Changes Of Yamuna River Floodplain In Megacity Delhi -- Assessing Urban Compactness Using Machine Learning And Earth Observation Datasets: A Case Study Of Kolkata City -- Analysis Of Ecological Vulnerability Behind The Land Conversion From Agriculture To Aquaculture Of Purba Medinipur District In West Bengal, India -- Environmental Change Analysis Using Remote Sensing And Gis: A Study Of Upper Baitarani Basin, Odisha -- Mapping Urban Footprint Using Machine Learning And Public Domain Datasets.
    Abstract: This book introduces the use of various remote sensing data such as microwave, hyperspectral and very high-resolution (VHR) satellite imagery; mapping techniques including pixel and object-based machine learning; and geostatistical modelling techniques including cellular automation, entropy and land fragmentation. Remote sensing plays a vital role in solving urban and environmental challenges at the landscape level. Globally, more than half of the urban population is facing severe environmental and social challenges, especially those relating to climate change, agricultural land encroachment, green infrastructure and environmental degradation, mobility due to rapid rural–urban transformation and anthropogenic interventions. Mapping and quantification of such threats at the landscape level are challenging for experts using traditional techniques; however, remote sensing technology provides diverse spatial data at a varying scale, volume and accessibility for mapping and modelling, and it also analyses challenges at urban and landscape levels. Together, they address challenges at urban and landscape levels to support the Sustainable Development Goals (SDGs).
    Type of Medium: Online Resource
    Pages: XIII, 317 p. 153 illus., 129 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819930067
    Series Statement: Advances in Geographical and Environmental Sciences,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Big data. ; Database management. ; Algorithms. ; Data mining. ; Geographical Information System. ; Big Data. ; Database Management. ; Algorithms. ; Data Mining and Knowledge Discovery.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Remote Sensing -- Chapter 3: Special Features of Remote Sensing Big Data -- Chapter 4: Remote Sensing Big Data Collection Challenges and Cyberinfrastructure and Sensor Web Solutions -- Chapter 5: Remote Sensing Big Data Computing -- Chapter 6: Remote Sensing Big Data Management -- Chapter 7: Standards for Big Data Management -- Chapter 8: Implementation Examples of Big Data Management Systems for Remote Sensing -- Chapter 9: Big Data Analytics for Remote Sensing-Concepts and standards -- Chapter 10: Big Data Analytic Platforms -- Chapter 11: Algorithmic Design Considerations of Big Data Analytics -- Chapter 12: Machine learning and data mining algorithms for geospatial big data -- Chapter 13: Modeling, prediction, and decision making based on remote sensing big data -- Chapter 14: Examples of remote sensing applications of big data analytics-fusion of diverse earth observation data -- Chapter 15: Examples of remote sensing applications of big data analytics-agricultural drought monitoring and forecasting -- Chapter 16: Examples of remote sensing applications of big data analytics-land cover time series creation -- Chapter 17: Geospatial big data initiatives in the world -- Chapter 18: Challenges and opportunities in remote sensing big data.
    Abstract: This monograph provides comprehensive coverage of the collection, management, and use of big data obtained from remote sensing. The book begins with an introduction to the basics of big data and remote sensing, laying the groundwork for the more specialized information to follow. The volume then goes on to address a wide variety of topics related to the use and management of remote sensing big data, including hot topics such as analysis through machine learning, cyberinfrastructure, and modeling. Examples on how to use the results of big data analysis of remotely sensed data for concrete decision-making are offered as well. The closing chapters discuss geospatial big data initiatives throughout the world and future challenges and opportunities for remote sensing big data applications. The audience for this book includes researchers at the intersection of geoscience and data science, senior undergraduate and graduate students, and anyone else interested in how large datasets obtained through remote sensing can be best utilized. The book presents a culmination of 30 years of research from renowned spatial scientists Drs. Liping Di and Eugene Yu.
    Type of Medium: Online Resource
    Pages: XI, 295 p. 104 illus., 95 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031339325
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Environmental monitoring. ; Dynamics. ; Nonlinear theories. ; Geography. ; Environmental sciences Mathematics. ; Geographical Information System. ; Environmental Monitoring. ; Applied Dynamical Systems. ; Geography. ; Mathematical Applications in Environmental Science.
    Description / Table of Contents: 1 Introduction -- 2 Basic terms and general principles of information processing -- 3 Basics from computer science -- 4 Spatial objects and reference systems -- 5 Digital spatial data: Data mining, geographic reference data and VGI -- 6 Standards and interoperability of spatial data -- 7 Visualization of spatial information -- 8 Data organization and database systems -- 9 Geographic information systems -- 10 Remote sensing and digital image processing.
    Abstract: This textbook is intended to display a broad, methodological introduction to geoinformatics and geoinformation science. It deals with the recording, modeling, processing and analysis as well as presenting and distributing of geodata. As an integrated approach it is dedicated to the multidisciplinary application of methods and concepts of computer science to solve spatial tasks. First the reader receives an introduction to the approach and tasks of geoinformatics, basic concepts and general principles of information processing as well as essentials of computer science. Then this textbook focuses on the following topics: spatial reference systems, digital spatial data, interoperability of spatial data, visualization of spatial information, data organization and database systems, geoinformation systems, remote sensing and digital image processing. The result is a comprehensive manual for studies and practical applications in geoinformatics. It serves also as a basis to support and deepen methodological courses in geography, geology, geodesy and surveying as well as all environmental sciences. In this first English edition, the author has updated and significantly expanded the fourth German edition. New additions include the development of apps, graphical presentation on the web, geodata-bases and recent methods of classification. This book is based on the original German 4th edition Geoinformatik in Theorie und Praxis by Norbert de Lange, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2020 and still presents the only integrated perspective on geoinformatics and geoinformation science. This book was translated with the help of artificial intelligence (machine translation by the service DeepL.com) first and then significantly revised with regard to technical terms and special topics of geoinformatics. The author Norbert de Lange taught and conducted research at the Institutes of Geography at the Universities of Münster and Osnabrück, Germany. In 2005, he was involved in founding the Institute for Geoinformatics and Remote Sensing at the University of Osnabrück, which has merged with the Institute for Computer Science and where he has been a Professor of Environmental Informatics and Municipal Planning since 2016. His main research focuses on applications of geoinformatics in urban and regional planning. For more than 40 years he has been teaching courses on geoinformation systems, digital cartography and data analysis in earth sciences.
    Type of Medium: Online Resource
    Pages: XVI, 519 p. 217 illus., 146 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783662657584
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Environment. ; Geography. ; Geographical Information System. ; Environmental Sciences. ; Geography.
    Description / Table of Contents: Chapter 1: Introduction to ArcGISPro -- Chapter 2: Data Classification and Layout in ArcGISPro -- Chapter 3: Data Acquisition -- Chapter 4: Coordinate Systems and Projections -- Chapter 5: Working with Geodatabase -- Chapter 6: Data Editing and Topology -- Chapter 7: Geoprocessing -- Chapter 8: Site Suitability and Data Modelling -- Chapter 9: Geocoding -- Chapter 10: Working with Raster -- Chapter 11: Spatial Interpolation -- Chapter 12: Watershed Delineation -- Chapter 13: Special Statistics -- Chapter 14: Network Analyst -- Chapter 15: 3-D Analyst -- Chapter 16: ArcGIS Online and Web Maps.
    Abstract: This textbook serves as a practical guide for undergraduate and graduate students in geology, hydrology, ecology, and environmental sciences, teaching them applied GIS techniques. Presented as a step-by-step tutorial across seventeen chapters, the book starts with the fundamentals of GIS and progresses to real-life examples from geology and water resources. The focus is on ESRI's ArcGIS Pro, covering various tools for spatial, geostatistical, network, and 3-D analysis. Additionally, it explores ArcGIS Online and working with web apps like Web Map, StoryMaps, and GEO App. GIS applications, especially in water and environmental problem-solving, are rapidly growing worldwide. The demand for GIS experts utilizing spatial analysis in environmental science remains high. This textbook equips users with the necessary knowledge to become effective mappers and spatial analysts in the fields of environment, geosciences, and water resources, employing the latest state-of-the-art methodology. Each chapter provides exercises and supplementary materials available for download on SpringerLink, along with additional links for further learning opportunities.
    Type of Medium: Online Resource
    Pages: XIX, 424 p. 669 illus., 653 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031422270
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Geographic information systems. ; Physical geography. ; Geomorphology. ; Geographical Information System. ; Physical Geography. ; Geomorphology.
    Description / Table of Contents: Chapter 1. Earth’s Gravity Field and Some of its Properties -- Chapter 2. Elementary Potential Theory -- Chapter 3. Spherical Harmonics -- Chapter 4. Normal Gravity Field and Reference Earth Ellipsoid -- Chapter 5. Stokes’ Theory and Beyond -- Chapter 6. Gravity Reduction -- Chapter 7. Molodensky’s Theory and Beyond -- Chapter 8. Fundamentals of Computation and Determination -- Chapter 9. Flattening and Gravity Inside the Earth.
    Abstract: This textbook introduces physical geodesy. It treats the boundary-value theories of the discipline comprehensively, and provides insights to the theory of gravity reduction based on a spherical Earth model. This book is for students who wish to thoroughly understand the material and to expand their knowledge and skills in mathematics for more advanced study and research in this discipline. The details of mathematical derivations included are a useful asset for instructors and researchers.
    Type of Medium: Online Resource
    Pages: XXI, 501 p. 96 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031233203
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Oncology. ; Immunology. ; Metastasis. ; Cytology. ; Cancer Biology. ; Oncology. ; Immunology. ; Metastasis. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Systemic View of Metastatic Disease: Inter-organ Crosstalk and Therapeutic Implications -- Part I. Systemic Regulation in Metastatic Disease -- Chapter 2. Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles -- Chapter 3. Bone Metastasis: Systemic Regulation and Impact on Host -- Chapter 4. Targeting Metastatic Disease: Challenges and New Opportunities -- Part II. Cachexia: A Debilitating Systemic Effect of Cancer -- Chapter 5. Signaling Pathways That Promote Muscle Catabolism in Cachexia -- Chapter 6. The Role of Interleukin-6 Cytokines in Cancer Cachexia -- Chapter 7. NF-kB Signaling in the Macroenvironment of Cancer Cachexia -- Part III. Therapy-induced Muscle Wasting -- Chapter 8. Therapy-induced Toxicities Associated with the Onset of Cachexia -- Chapter 9. Bone-muscle Crosstalk in Advanced Cancer and Chemotherapy -- Part IV. Preventing and Targeting Cachexia in Cancer -- Chapter 10. New Developments in Targeting Cancer Cachexia -- Chapter 11. Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer.
    Abstract: This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-kB, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology.
    Type of Medium: Online Resource
    Pages: VI, 203 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031095184
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Tumors Immunological aspects. ; Cancer Treatment. ; Biochemistry. ; Metabolism. ; Cell biology. ; Immunology. ; Cancer Biology. ; Cancer Microenvironment. ; Tumour Immunology. ; Cancer Therapy. ; Metabolic Pathways. ; Immunology.
    Description / Table of Contents: 1 Cancer Metabolism and Aggressive Tumor Behaviour -- 2 Immune Cell Metabolism and Function -- 3 Cancer Cell Metabolism Effecting Immune function -- 4 Immune Cell Metabolites as Fuel for Cancer Cells -- 5 Immuno-Onco metabolism and Resistance to Therapy -- 6 Targeting Immuno-Onco metaolism in Cancers -- 7 Timing of the major metabolic switches in immune cell activation and differentiation during cancer development.
    Abstract: This book discusses the novel metabolic cross-talk between immune and tumor cells in the tumor microenvironment that promotes their growth and progression. It also describes deregulated metabolism in cancer cells that promotes suppressive and cancer cell-favourable microenvironment. Further, the book provides novel insights on the metabolic changes in immune cells that promote tumor cell growth and survival. In turn, it also reviews the involvement of immuno-onco metabolic cross-talk in the development of resistance to chemo-radiation therapy (CRT) in tumor cells. Lastly, it also explores the potential of immuno-oncology metabolism as a therapeutic approach against tumor cells.
    Type of Medium: Online Resource
    Pages: X, 218 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811662263
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Metastasis. ; Lymphatics. ; Cancer Biology. ; Metastasis. ; Lymphatic System.
    Description / Table of Contents: Section 1: Genetic and Molecular Pathways of Cancer Growth and Metastasis -- Chapter 1. Hallmarks of Cancer: Molecular Underpinnings -- Chapter 2. Unifying concept of genomic changes: The mutational landscape of cancers -- Chapter 3. Tumor Microenvironment: Coconspirator in Tumorigenesis -- Chapter 4. Hallmarks of Metastasis: Molecular Underpinnings -- Chapter 5. Hereditary Cancer Syndromes and Cancer Metastasis -- Section 2: Pathology of Cancer Growth and Metastasis -- Chapter 6. Pathologic Assessment of Lymph Node Metastasis -- Chapter 7. Pathologic Assessment of Systemic or Distant Metastasis -- Chapter 8. The Role of Angiotropic Extravascular Migratory Metastasis in Metastases -- Section 3: Dormant Cancer Cells and their Reactivation in the Host Cancer Microenvironment -- Chapter 9. Tumor Dormancy and Relapse Regulated by the Extracellular Matrix -- Chapter 10. Therapy-Induced Dormancy and Residual Disease -- Section 4: The Microenvironment of Site-Specific Metastasis - Isaac P. Witz -- Chapter 11. The Microenvironment of Site-Specific Metastasis -- Section 5: Circulating Cancer Cells and Liquid Biopsy -- Chapter 12. Circulating tumor cells and ctDNA in sarcomas -- Chapter 13. Liquid biopsy using cell-free tumor DNA for gastrointestinal cancers -- Chapter 14. Circulating tumor cells and ctDNA in prostate cancer.-Chapter 15. Circulating Tumor Cells in Lung Cancer -- Chapter 16. CTCs/ ctDNA and Brain Metastasis.-Chapter 17. Epigenetics and liquid biopsy in oncology: role in metastasis and clinical utility -- Chapter 18. Metabolic reprogramming of circulating tumor cells for metastasis -- Section 6: Lymphatic System and Cancer Metastasis -- Chapter 19. Lymphatic System Biology, Pathobiology, and Relation to Cancer Metastasis -- Chapter 20. Lymphatic Specification and Development, EMT-MET, and Cancer Spread -- Chapter 21. Lymphangiogenesis, Lymph Nodes, Cancer Lymphangiogenesis and Metastasis -- Chapter 22. Immune cell trafficking in the lymphatics, hyaluronan biology and tumour metastasis -- Chapter 23. Lymphvascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis -- Chapter 24. Imaging of the Lymphatic System with Relevance to Cancer and Cancer Metastasis -- Chapter 25. Lymphedema: general pathophysiology, prevention and management in invasive cancer -- Section 7: Radiological Imaging of Early Cancer and Cancer Metastases -- Chapter 26. Primary Tumor Staging and Detection of Common Sites of Distant Metastatic Disease -- Chapter 27. Imaging Modalities in the Detection and Diagnosis of Metastatic Disease -- Chapter 28. Imaging of Bone Metastases -- Chapter 29. Imaging of Lung and Soft Tissue Metastases -- Chapter 30. Image-Guided Biopsy and Intervention for Metastatic Disease -- Section 8: Sentinel Lymph Node Surgery for Solid Cancer. Chapter 31. Sentinel Lymph Node Biopsy for Primary Cutaneous Malignancy -- Chapter 32. Sentinel Lymph Node Biopsy in Breast Cancer -- Chapter 33. Sentinel node navigation surgery for upper gastrointestinal cancer -- Chapter 34. Sentinel Lymph Node Mapping in Non-Small Cell Lung, Colon, and Thyroid Carcinomas -- Section 9: Surgical Treatment of Primary and Metastatic Cancer -- Chapter 35. The efficacy and evolution of surgical management based on cancer biology -- Chapter 36. The role of surgery in managing primary and metastatic melanoma -- Chapter 37. The Role of Surgery in Managing Primary and Metastatic Breast Cancer -- Chapter 38. The role of surgery in managing primary and metastatic colorectal cancer -- Chapter 39. The Role of Surgery in Management of Gastric Cancer -- Chapter 40. The role of surgery in managing primary and metastatic hepatopancreaticobiliary cancers -- Section 10: Cancer Metastasis to the Lung -- Chapter 41. Metastatic disease of the lung -- Section 11: Cancer Metastasis to the Liver -- Chapter 42. Tumor Resection and Ablation as a Means of Controlling Hepatic Metastases -- Chapter 43. Regional Arterial Infusional Therapy as a Means of Controlling Hepatic Metastases -- Section 12: Cancer Metastasis to the Bone -- Chapter 44. Molecular Mechanisms of Metastasis to the Bone.-Chapter 45. Surgical Management of Metastatic Disease to the Upper Extremity -- Chapter 46. Surgical Management of Metastatic Disease to the Lower Extremity -- Chapter 47. Surgical management of metastatic disease to the pelvis -- Chapter 48. Surgical Management of Metastatic Disease to the Spine -- Chapter 49. Interventional radiology techniques for management of skeletal metastases -- Section 13: Cancer Metastasis to the Brain and the Nervous System -- Chapter 50. Brain Metastases: Overview and Molecular Mechanisms -- Chapter 51. Indications and Techniques for Surgical Intervention in Patients with Metastatic Brain Tumors -- Chapter 52. Brain Metastases: Current and Future pharmacological treatment -- Chapter 53. Radiotherapy for CNS Metastases -- Chapter 54. Leptomeningeal Carcinomatoses -- Section 14: Urologic Cancer and 1st Patterns of Metastasis -- Chapter 55. Urologic Cancer and 1st Patterns of Metastasis -- Section 15: Biology and Clinical Aspects of Sarcoma Progression -- Chapter 56. Soft Tissue Sarcoma -- Chapter 57. Bone Sarcoma -- Chapter 58. Liposarcoma Metastasis -- Chapter 59. Desmoid Tumors.-Chapter 60. Atypical patterns of metastases: How do Sarcoma’s metastasize? -- Chapter 61. Tumor Immune Microenvironment of Soft Tissue Sarcoma -- Section 16: The Role of Radiation in the Treatment of Primary and Metastatic Cancer -- Chapter 62. Basic Principles of Radiobiology and Cancer Metastasis Prevention -- Chapter 63. Technical Innovations in the Delivery of Radiation Therapy -- Chapter 64. Radiation Therapy in the Definitive Treatment of Cancer -- Chapter 65. Radiation Therapy for Extracranial Oligometastatic Disease -- Chapter 66. Spine Radiotherapy -- Section 17: Immunotherapy of Solid Malignancies -- Chapter 67. Immunotherapy in Melanoma and Merkel Cell Cancer -- Chapter 68. Landscape of Immunotherapy in Lung Cancer -- Chapter 69. Immuno-oncologic Treatment of Genitourinary Malignancies -- Section 18: Current Topics -- Chapter 70. Personalized Systemic Cancer Therapy -- Chapter 71. Cancer Stem Cells and Their Role in Metastasis -- Chapter 72. HPV Induced Cancers -- Chapter 73. Microbiome and Cancer Metastasis -- Chapter 74. Application of Artificial Intelligence in Research on Cancer and Its Metastasis.
    Abstract: This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
    Type of Medium: Online Resource
    Pages: XXIV, 806 p. 145 illus., 106 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030930844
    DDC: 571.978
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Tumor markers. ; Non-coding RNA. ; Cancers. ; Tumour Biomarkers. ; Non-coding RNAs.
    Description / Table of Contents: Chapter 1. The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective -- Chapter 2. Circulating MicroRNAs as Cancer Biomarkers in Liquid Biopsies -- Chapter 3. Regulation of Immune Cells by MicroRNAs and MicroRNA-Based Cancer Immunotherapy -- Chapter 4. Machine-Learning-Based Methods and Best Practices of MicroRNA-Target Prediction and Validation -- Chapter 5. Turning Data to Knowledge: Online Tools, Databases and Resources in MicroRNA Research -- Chapter 6. Bioinformatics Methods for Modeling MicroRNA Regulatory Networks in Cancer -- Chapter 7. Analysis of the p53/MicroRNA Network in Cancer -- Chapter 8. Machine Learning Using Gene-Sets to Infer miRNA Function -- Chapter 9. miRNA:miRNA Interactions: A Novel Mode of miRNA Regulation and Its Effect on Disease -- Chapter 10. ClustMMRA v2: A Scalable Computational Pipeline for the Identification of MicroRNA Clusters Acting Cooperatively on Tumor Molecular Subgroups -- Chapter 11. 3D Modeling of Non-coding RNA Interactions.
    Abstract: This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research. Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer. This book focuses on the emerging opportunities for the application of microRNA research in clinical practice. In this context, computer models are presented that can help to identify novel biomarkers, e.g. in circulating microRNAs, and tools that can help to design microRNA-based therapeutic interventions. Other chapters evaluate the role of microRNAs in immunotherapy, immune responses and drug resistance. Covering key topics on microRNAs in cancer research this book is a valuable resource for both emerging and established microRNA researchers who want to explore the potential of microRNAs as therapeutic targets or co-adjuvants in cancer therapies.
    Type of Medium: Online Resource
    Pages: VII, 317 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031083563
    Series Statement: Advances in Experimental Medicine and Biology, 1385
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Cytology. ; Clinical biochemistry. ; Cancer Biology. ; Cell Biology. ; Medical Biochemistry.
    Description / Table of Contents: Chapter 1: Small leucine-rich proteoglycans regulate cancer cell growth, apoptosis-and associated inflammation -- Chapter 2: The role of decorin in cancer -- Chapter 3: The mystery of syndecan-1 in tumor development and progression -- Chapter 4:Syndecan-2 Biology and its Role in Colorectal Carcinoma -- Chapter 5: Versican in Tumor Progression, Tumor-Host Interactions and Cancer Immunotherapy -- Chapter 6:Circulating proteoglycans/glycosaminoglycans as cancer biomarkers -- Chapter 7: Hyaluronan in the Extracellular Matrix of hematological and solid tumors. Its biological effects" -- Chapter 8: Heparanase: a paramount enzyme for cancer initiation, progression and metastasis -- Chapter 9: Laminins and matrix metalloproteinases connection: a subtle relationship that can go wrong in a tumor context, particularly if CD44 gets involved -- Chapter 10:Basement membrane, collagen, and fibronectin: physical interactions with cancer cells -- Chapter 11: Integrins in cancer: re-focusing on the tumor microenvironment -- Chapter 12: Adipose compounds in breast tumor extracellular matrix -- Chapter 13: Extracellular matrix as a metabolic niche in cancer -- Chapter 14: The role of inflammatory cells in tumor angiogenesis -- Chapter 15: Cancer angiogenesis and its master regulator perlecan -- Chapter 16: The microRNA-extracellular matrix interplay in breast cancer -- Chapter 17: The impact of the extracellular matrix on immunotherapy success -- Chapter 18: Exploiting hyaluronan-CD44 network in tumor therapy.
    Abstract: This book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression. Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression. Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics. The series "Biology of Extracellular Matrix" is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
    Type of Medium: Online Resource
    Pages: X, 494 p. 40 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030997083
    Series Statement: Biology of Extracellular Matrix, 11
    DDC: 571.978
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Cancer Epidemiology. ; Cancer Genetic aspects. ; Cancer Biology. ; Cancer Epidemiology. ; Cancer Genetics and Genomics.
    Description / Table of Contents: Module 1_Overview of Breast Cancer -- Module 2_Cell and Molecular Biology of Breast Cancer-Diagnosis and Prognosis -- Module 3_Breast Cancer Treatment.
    Abstract: This book provides detailed information on the etiology, pathogenesis, diagnosis, prognosis, and treatment strategies for breast cancer. The first section of the book presents epidemiology, risk factors, histopathological, immunohistochemistry, and molecular subtypes of breast cancer based on the receptor status. It also discusses the association of breast cancer with other hormone-sensitive cancers. The second section of the book covers cover BRCA1 and BRCA2-associated breast carcinogenesis, early-stage progression of breast cancer, and noninvasive biomarkers for the early detection of breast cancer. It also discusses the role of epigenetic modifications and non-coding RNAs in breast cancer metastasis and explores these as the biomarkers and therapeutic targets for breast cancer therapy. Further, it discusses the role of fibrinolytic mechanisms and circulating tumor cells in breast cancer diagnosis, prognosis, and treatment. The book also provides an update on oral poly(ADP-ribose) polymerase (PARP) inhibitors to treat breast cancer. Finally, it offers potential new options for personalized therapies for breast cancer patients, including optimizing drug dosage and identifying genetic changes associated with cancer symptom occurrence and severity.
    Type of Medium: Online Resource
    Pages: XVII, 536 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811901973
    DDC: 571.978
    Language: English
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    Keywords: Geographic information systems. ; Quantitative research. ; Artificial intelligence. ; Medical care. ; Geographical Information System. ; Data Analysis and Big Data. ; Artificial Intelligence. ; Health Care.
    Description / Table of Contents: Potential of Geospatial Data in Healthcare for Society 5.0 -- Geospatial Health Data Analytics for Society 5.0 -- Relevance of spatio-temporal data visualisation techniques in healthcare system -- GIS and Remote Sensing for public health -- Infectious diseases and their tracking in GIS.
    Abstract: The book introduces a variety of latest techniques designed to represent, enhance, and empower multi-disciplinary approaches of geographic information system (GIS), artificial intelligence (AI), deep learning (DL), machine learning, and cloud computing research in healthcare. It provides a unique compendium of the current and emerging use of geospatial data for healthcare and reflects the diversity, complexity, and depth and breadth of this multi-disciplinary area. This book addresses various aspects of how smart healthcare devices can be used to detect and analyze diseases. Further, it describes various tools and techniques to evaluate the efficacy, suitability, and efficiency of geospatial data for health-related applications. It features illustrative case studies, including future applications and healthcare challenges. This book is beneficial for computer science and engineering students and researchers, medical professionals, and anyone interested in using geospatial data in healthcare. It is also intended for experts, offering them a valuable retrospective and a global vision for the future, as well as for non-experts who are curious to learn about this important subject. The book presents an effort to draw how we can build health-related applications using geospatial big data and their subsequent analysis.
    Type of Medium: Online Resource
    Pages: VIII, 318 p. 116 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811694769
    Series Statement: Disruptive Technologies and Digital Transformations for Society 5.0,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Environmental geography. ; Public health. ; Big data. ; Epidemiology. ; Geographical Information System. ; Integrated Geography. ; Public Health. ; Big Data. ; Epidemiology.
    Description / Table of Contents: Chapter 1-Building the analytic toolbox-from spatial analytics to spatial statistical inference with geospatial data -- Chapter 2-Spatial data integration to better represent pollutants for environmental health studies -- Chapter 3-Spatial health data analysis-data driven and model driven approaches. Chapter 4 -- Machine learning, big data and spatial tools-a combination to reveal complex facts that impact environmental health -- Chapter 5-Spatial aspects of seasonality and infectious diseases -- Chapter 6-Earth observation data and technology to model influenza epidemiology -- Chapter 7-Trend of geospatial technology in environmental health application-from public health to individual healthcare -- Chapter 8-Geospatial technology to analyze human well-being and its eco-social determinants -- Chapter 9-Spatial components of population health -- Chapter 10-Geospatial technology in medical geology -- Chapter 11-Geospatial technology in planning and operations of telehealth programs -- Chapter 12-Integrating GIS, toxicology, microbiology and geochemistry-a multidisciplinary integrated approach for better understanding the public health issues.
    Abstract: Over the last thirty years or so, there have been tremendous advancements in the area of geospatial health; however, somehow, two aspects have not received as much attention as they should have received. These are a) limitations of different spatial analytical tools and b) progress in making geospatial environmental exposure data available for advanced health science research and for medical practice. This edited volume addresses those two less explored areas of geospatial health with augmented discussions on the theories, methodologies and limitations of contemporary geospatial technologies in a wide range of applications related to human well-being and health. In 20 chapters, readers are presented with an up-to-date assessment of geospatial technologies with an emphasis on understanding general geospatial principles and methodologies that are often overlooked in the research literature. As a result, this book will be of interest to both newcomers and experts in geospatial analysis and will appeal to students and researchers engaged in studying human well-being and health. Chapters are presenting new concepts, new analytical methods and contemporary applications within the framework of geospatial applications in human well-being and health. The topics addressed by the various chapter authors include analytical approaches, newer areas of geospatial health application, introduction to unique resources, geospatial modeling, and environmental pollution assessments for air, water and soil. Although geospatial experts are expected to be the primary readers, this book is designed in such a way so that the public health professionals, environmental health scientists and clinicians also find it useful with or without any familiarity with geospatial analysis.
    Type of Medium: Online Resource
    Pages: XVIII, 417 p. 141 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030713775
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Statistics . ; Computer science Mathematics. ; Mathematical statistics. ; Functions of complex variables. ; Algorithms. ; Geographical Information System. ; Statistics in Engineering, Physics, Computer Science, Chemistry and Earth Sciences. ; Probability and Statistics in Computer Science. ; Several Complex Variables and Analytic Spaces. ; Algorithms.
    Description / Table of Contents: Chapter 1: Binary Variable Versus Binary Variable -- Chapter 2: Binary Variable Versus Rank Variable -- Chapter 3: Application of the Total Operating Characteristic -- Chapter 4: Categorical Variable Versus Categorical Variable -- Chapter 5: Application to Categorical Error Assessment with Sampling -- Chapter 6: Multiple Spatial Resolutions for Categorical Variables -- Chapter 7: Application to Categorical Temporal Change -- Chapter 8: Interval Variable Versus Interval Variable -- Chapter 9: Application to Interval Temporal Change -- Chapter 10: Indices of Agreement -- Chapter 11: Vector Variable Versus Vector Variable -- Chapter 12: Commandments to Avoid Deadly Sins.
    Abstract: Your government warns that 10% of your neighbors have a deadly contagious virus. The producer of a diagnostic test advertises that 90% of its tests are correct for any population. The test indicates that you have the virus. This book’s author claims your test has a 50% chance of being false, given your test’s result. Who do you believe? This book gives you insights necessary to interpret metrics that make a difference in life’s decisions. This book gives methods and software that are essential to analyse change and error. Change describes a phenomenon across time points. Error compares diagnoses with the truth. Other texts give insufficient attention to these topics. This book’s novel ideas dispel popular misconceptions and replace previous methods. The author uses carefully designed graphics and high school mathematics to communicate easily with college students and advanced scientists. Applications include but are not limited to Remote Sensing, Land Change Science, and Geographic Information Science. “A wide range of tools to aid understanding of land cover and its change has been used but scientific progress has sometimes been limited through misuse and misunderstanding. Professor Pontius seeks to rectify this situation by providing a book to accompany the researcher’s toolbox. Metrics That Make a Difference addresses basic issues of relevance to a broad community in a mathematically friendly way and should greatly enhance the ability to elicit correct information. I wish this book existed while I was a grad student.” – Giles Foody, Professor of Geographical Information Science, The University of Nottingham “Metrics That Make a Difference provides a comprehensive synthesis of over two decades of work during which Dr. Pontius researched, developed, and applied these metrics. The book meticulously and successfully guides the reader through the conceptual basis, computations, and proper interpretation of the many metrics derived for different types of variables. The book is not just a mathematical treatise but includes practical guidance to good data analysis and good science. Data scientists from many fields of endeavor will benefit substantially from Dr. Pontius’ articulate review of traditionally used metrics and his presentation of the innovative and novel metrics he has developed. While reading this book, I had multiple ‘aha’ moments about metrics that I shouldn't be using and metrics that I should be using instead.” – Stephen Stehman, Distinguished Teaching Professor, State University of New York.
    Type of Medium: Online Resource
    Pages: XXI, 117 p. 17 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030707651
    Series Statement: Advances in Geographic Information Science,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Environmental monitoring. ; Physical geography. ; Environment. ; Geographical Information System. ; Environmental Monitoring. ; Earth System Sciences. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1-Why this Topic? -- Chapter 2-Global Warming Impact on Earth Systems -- Chapter 3-The IPCC Reports on Global Warming and Land Changes -- Chapter 4.NOAA Operational Environmental Satellites for Earth Monitoring -- Chapter 5-New Remote Sensing Vegetation Health Technology -- Chapter 6-Cause of Climate Warming -- Chapter 7- Land Cover Changes from Intensive Climate Warming -- Chapter 8-Global Warming Crop Yield and Food Security -- Chapter 9-Remote Sensing Malaria During Global Warming -- Chapter 10-Malaria Performance Trend During 1981-2022 -- Chapter 11-Remote Sensing Drought Watch and Food Security -- Chapter 12-Has Drought Intensified During 1981-2021 Global Warming?
    Abstract: This book discusses the detrimental consequences of climate-related land changes over a 40-year period between 1981 and 2020, and focuses on how climate warming is deteriorating the agricultural system due to excessive heat, lack of moisture and more intensive and widespread droughts leading to a reduction of agricultural production. Most of the existing literature on the unfavourable consequences of global warming for land are based on a relatively short period of weather station data, covering local land areas with limited networks and monitoring parameters. These concerns have led to the use of satellite data, whose measurements are controlled by such vegetation characteristics as chlorophyll, carotenoids, moisture contents in the plants and temperature inside the vegetation community. Therefore, the discussion of this book is completely based on high-resolution global land surface measurements by the sensors on the National Oceanic and Atmospheric Administration’s (NOAA) operational afternoon polar-orbiting satellites. The book also focuses on understanding climate change impacts on land changes where humans are living, and combines biophysically-grounded methods and the 40-year data to develop models for monitoring large-scale Earth warming impacts on land and for timely prediction of climate consequences for humans. These 40-year trends in land characteristics will help to better inform the assessment of potential changes in the future and how to reach human sustainability. The book will of interest to scientists using satellite remote sensing to track climate change impacts on land over time, as well as students and researchers in climatology and environmental sustainability. .
    Type of Medium: Online Resource
    Pages: IX, 462 p. 159 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968106
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Machine learning. ; Signal processing. ; Geology. ; Environmental monitoring. ; Geographical Information System. ; Machine Learning. ; Signal, Speech and Image Processing . ; Geology. ; Environmental Monitoring.
    Description / Table of Contents: Preface.-Mine geological environment: An overview.-Multimodal remote sensing science and technology.-Deep learning technology for remote sensing intelligent interpretation.-Remote sensing interpretation signs of mine land occupation type -- Mine remote sensing dataset construction for multi-level tasks -- Mine target detection by remote sensing and deep learning -- Mine remote sensing scene classification by deep learning -- Mine land occupation classification based on machine learning and remote sensing images -- Mine land occupation classification based on deep learning and remote sensing images -- Concluding remarks.
    Abstract: This book examines the theory and methods of remote sensing intelligent interpretation based on deep learning. Based on geological and environmental effects on mines, this book constructs a set of systematic mine remote sensing datasets focusing on the multi-level task with the system of “target detection→scene classification→semantic segmentation." Taking China’s Hubei Province as an example, this book focuses on the following four aspects: 1. Development of a multiscale remote sensing dataset of the mining area, including mine target remote sensing dataset, mine (including non-mine areas) remote sensing scene dataset, and semantic segmentation remote sensing dataset of mining land cover. The three datasets are the basis of intelligent interpretation based on deep learning. 2. Research on mine target remote sensing detection method based on deep learning. 3. Research on remote sensing scene classification method of mine and non-mine areas based on deep learning. 4. Research on the fine-scale classification method of mining land cover based on semantic segmentation. The book is a valuable reference both for scholars, practitioners and as well as graduate students who are interested in mining environment research.
    Type of Medium: Online Resource
    Pages: XII, 246 p. 110 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811937392
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Geography. ; Computer programming. ; Geographical Information System. ; Geography. ; Programming Techniques.
    Description / Table of Contents: Chapter 1. Introduction to Scripting and Programming -- Chapter 2. Basics of programming—Variables, Operators, & Statements -- Chapter 3. Basics of programming—Control Structures -- Chapter 4. Basics of programming—Functions and Objects -- Chapter 5. Reading a Python Script -- Chapter 6. Debugging -- Chapter 7. Introduction to ArcPy -- Chapter 8. Basics of accessing data in ArcGIS -- Chapter 9. Rasters -- Chapter 10. Tables and Cursors -- Chapter 11. Vectors and Geometries -- Chapter 12. Mapping--symbologies -- Chapter 13. Mapping—layouts -- Chapter 14. Creating custom tools -- Chapter 15. Error Handling -- Chapter 16. Creating Custom Classes -- Chapter 17. Putting it all together -- Chapter 18. ArcPy for Web GIS using ArcGIS Online -- Chapter 19. Incorporating External Packages -- Chapter 20. Using Multiple Python Files -- Chapter 21. Developing a Custom Python Package.
    Abstract: This upper-undergraduate textbook teaches students programming in GIS using a mix of computer science theory and hands-on activities, with the aim of empowering students to understand fundamentals and apply their knowledge beyond the specific examples in the book. Each of the book’s twenty-one chapters integrates instructional material with exercises in ArcGIS Pro. In doing so, this book combines the strengths of workbooks and theoretical textbooks to provide a holistic and comprehensive text. Each chapter concludes with an unguided task that ensures students have learned the broader principles explained therein. In addition to its unique format, the book covers oft-neglected topics such as debugging, creating a program from scratch, and managing metadata. Section I starts with the principles of scripting and programming with Python. Section II introduces the ArcPy module and elements specific to ArcGIS Pro. This section focuses on data structures, and how they are used and implemented within Python. Section III uses the topic of algorithms to guide the student through creating tools to add functionality to ArcGIS Pro. The last section, Section IV, builds upon section III to guide the student to developing and sharing projects and Python packages to include external open-source code and share the Python code as an open-source package. This text will prepare students for a long-term ability to do GIS programming, whether in industry or academic research. This comes from the author’s observations of students who have learned GIS programming in one platform, such as VBA in ArcMap, struggle to apply that knowledge to a new platform, such as Python in ArcGIS Pro, because the content was presented too closely with a specific platform. The integration of exercises with conceptual content, along with the choice of chapter content, serves this goal of preparing students for working in a dynamic, rapidly changing technology field.
    Type of Medium: Online Resource
    Pages: XII, 267 p. 110 illus., 88 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084980
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Tumor markers. ; Cancer. ; Cancer Treatment. ; Nanomedicine. ; Tumour Biomarkers. ; Cancer Biology. ; Cancer Therapy. ; Cancer Nanotechnology.
    Description / Table of Contents: Chapter 1. Introduction to cancer biomarkers -- Chapter 2.Technologies for identification and validation of cancer biomarkers -- Chapter 3. BIOMARKERS FOR CANCER DRUG DEVELOPMENT -- Chapter 4. Clinical proteomics: diagnostics and prognostic markers of Cancer -- Chapter 5.Microbiome as cancer biomarkers -- Chapter 6. Predictive biomarkers for anticancer drugs -- Chapter 7. Biomarkers in Cancer Survival and Drug Resistance -- Chapter 8. Biomarkers in tumor recurrence and metastasis -- Chapter 9. Biomarkers for Cancer Immunotherapy -- Chapter 10. Role of Biomarkers in Personalized Medicine -- Chapter 11.Development of Novel Cancer Biomarkers for Diagnosis and Prognosis -- Chapter 12. Nanotechnology for Cancer Biomarkers.
    Abstract: This book illustrates the basics and underlying molecular machinery of cancer cells and biochemical assays that detect the type and stage of cancer through cell signaling biomarkers. It starts with a brief introduction to cancer biomarkers and addresses technologies for identifying and validating cancer biomarkers, biomarkers for cancer drug development, prognostic and diagnostic biomarkers, and microbiome as cancer biomarkers. It reviews predictive biomarkers for anticancer drugs, biomarkers in cancer survival and drug resistance, biomarkers in tumor recurrence and metastasis, the role of the biomarker in immunotherapy and personalized medicine, and the development of a novel cancer biomarker. Finally, this book also underpins the role of nanotechnology in the use and detection of cancer biomarkers for enhanced sensitivity and specificity. Lastly, it discusses the challenges with biomarkers in cancer drug discovery and development. This volume is an indispensable tool for researchers working in the field of cancer and also for clinical oncologists.
    Type of Medium: Online Resource
    Pages: XII, 365 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811657597
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Biochemical markers. ; Microfluidics. ; Pharmacology. ; Cancer Treatment. ; Cancer Biology. ; Biomarkers. ; Microfluidics. ; Pharmacology. ; Cancer Therapy.
    Description / Table of Contents: Part 1. Fundamentals of Microfluidics and Biosensors -- Chapter 1. Fundamentals of Biosensors and Detection Methods -- Chapter 2. How to Get Away with Gradients -- Chapter 3. Sensors and Biosensors in Organs-on-a-chip Platforms -- Chapter 4. Current Trends in Microfluidics and Biosensors for Cancer Research Applications -- Part 2. Modelling the Tumor Microenvironment and Its Dynamic Events -- Chapter 5. The Tumor Microenvironment — an Introduction for the Development of Microfluidic Devices -- Chapter 6. Biomaterials for Mimicking and Modelling Tumor Micro-environment -- Chapter 7. Advancing Tumor Microenvironment Research by Combining Organs-on-chips and Biosensors -- Chapter 8. Microfluidic-driven Biofabrication and the Engineering of Cancer-like Microenvironments -- Chapter 9. Advances in 3d Vascularized Tumor-on-a-chip Technology -- Part 3. Cancer Detection and Diagnosis -- Chapter 10. Biosensors Advances: Contributions to Cancer Diagnostics and Treatment -- Chapter 11. Flexible Sensing Systems for Cancer Diagnostics -- Chapter 12. Coupling Micro-physiological Systems and Biosensors for Improving Cancer Biomarkers Detection -- Chapter 13. Microfluidic Biosensor-based Devices for Rapid Diagnosis and Effective Anti-cancer Therapeutic Monitoring for Breast Cancer Metastasis -- Chapter 14. Liquid Biopsies: Flowing Biomarkers -- Chapter 15. From Exosomes to Circulating Tumor Cells: Using Microfludics to Detect High Predictive Cancer Biomarkers -- Chapter 16. Microfluidics for the Isolation and Detection of Circulating Tumor Cells -- Chapter 17. Evolution in Automatized Detection of Cancer Cells: Advances in Magnetic Microcytometers -- Chapter 18. Droplet-based Microfluidic Chip Design, Fabrication and Use for Ultrahigh-throughput DNA Analysis and Quantification -- Chapter 19. Emerging Microfluidic and Biosensor Technologies for Improved Cancer Theranostics -- Part 4. Clinical Applications: Towards Personalized Medicine -- Chapter 20. Microfluidics for Cancer Biomarker Discovery, Research and Clinical Application -- Chapter 21. Methods for the Detection of Circulating Biomarkers in Cancer Patients -- Chapter 22. Advances in Microfluidics for the Implementation of Liquid Biopsy in Clinical Routine.
    Abstract: This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics. Over the last decades, considerable effort has been made to develop new technologies to improve the diagnosis and treatment of cancer. Microfluidics has proven to be a powerful tool for manipulating biological fluids with high precision and efficiency and has already been adopted by the pharmaceutical and biotechnology industries. With recent technological advances, particularly biosensors, microfluidic devices have increased their usefulness and importance in oncology and cancer research. The aim of this book is to bring together in a single volume all the knowledge and expertise required for the development and application of microfluidic systems and biosensors in cancer modeling and theranostics. It begins with a detailed introduction to the fundamental aspects of tumor biology, cancer biomarkers, biosensors and microfluidics. With this knowledge in mind, the following sections highlight important advances in developing and applying biosensors and microfluidic devices in cancer research at universities and in the industry. Strategies for identifying and evaluating potent disease biomarkers and developing biosensors and microfluidic devices for their detection are discussed in detail. Finally, the transfer of these technologies into the clinical environment for the diagnosis and treatment of cancer patients will be highlighted. By combining the recent advances made in the development and application of microfluidics and biosensors in cancer research in academia and clinics, this book will be useful literature for readers from a variety of backgrounds. It offers new visions of how this technology can influence daily life in hospitals and companies, improving research methodologies and the prognosis of cancer patients.
    Type of Medium: Online Resource
    Pages: XIX, 590 p. 100 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031040399
    Series Statement: Advances in Experimental Medicine and Biology, 1379
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Tumors Blood-vessels. ; Blood-vessels Growth. ; Cancer Imaging. ; Cancer Genetic aspects. ; Cancer Biology. ; Tumour Angiogenesis. ; Cancer Imaging. ; Cancer Genetics and Genomics.
    Description / Table of Contents: Part I: Basic Background -- Chapter 1. Fighting with Cancer: A Common Man’s Dilemma -- Chapter 2. Introduction to Cell Biology and Cell Behavior in Cancer -- Chapter 3. Tumor Biology: An Introduction -- Chapter 4. Role of Angiogenesis in Tumours -- Chapter 5. Biology, Chemistry and Physics of Cancer Cell Motility and Metastasis -- Part II: Diagnostics and Theory -- Chapter 6. MRI, CT and PETSCAN: Engineer’s Perspective -- Chapter 7. Diffusion, MRI and Cancer Diagnosis: Physicist’s Outlook -- Chapter 8. Oncology: Radiation Oncologist’s View -- Chapter 9. Oncology: Biochemists’ Perspective -- Chapter 10. Oncology: Pathologist’s View -- Part III: Cancer Therapeutics -- Chapter 11. Surgical Oncology: An Overview -- Chapter 12. Medical Oncology in Cancer Treatment -- Chapter 13. Chemotherapy Effects on Immune System -- Chapter 14. Telomerase and its therapeutic implications in Cancer -- Chapter 15. Pain Management in Oncology -- Part IV: Emerging Trends in Cancer Research -- Chapter 16. New Approaches in Cancer Research: Stem-cell research, Translational Research, Immuno-therapy, and others -- Chapter 17. Cancer Cell Lines: Its Implication for Therapeutic Use -- Chapter 18. Genomics of Cancer -- Chapter 19. Chapter 19: Diabetes and Cancer -- Chapter 20. Oncology Informatics, AI, and Drug Discovery -- Chapter 21. Radiomics: Cropping More from the Images -- Part V: Epidemiology and Statistics of Cancer -- Chapter 22. Statistics in Cancer: Diagnosis, Disease Progression, Treatment Efficacy and Patient Survival Studies -- Chapter 23. Epidemiology of Cancer: Asian Perspective -- Chapter 24. Cancer Genomics and Diagnostics: Northeast Indian Scenario.
    Abstract: This book presents multiple facets of cancer biology, including cancer diagnosis, therapeutics to the latest developments in cancer informatics, and applications of artificial intelligence for improving oncologic care. The initial section of the book discusses factors contributing to the development and causes of cancer. The subsequent sections discuss the basic principle of imaging and therapeutic techniques, including MRI, CT, and positron emission tomography (PET) Scan. The book further, explores the implications of cancer chemotherapy on the immune system and emphasizes the effective management of cancer-related pain. Towards the end, it covers recent advancements in cancer treatment, including targeted therapy, immunotherapy, interventional radiotherapy, and stem cell-based therapy. Lastly, it summarizes essential strategic elements of cancer informatics for improving patient outcome.
    Type of Medium: Online Resource
    Pages: XIX, 529 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647529
    DDC: 571.978
    Language: English
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  • 52
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Property. ; Common law. ; Industries. ; Economic geography. ; Geographical Information System. ; Common Property and Land Law. ; Industries. ; Economic Geography.
    Description / Table of Contents: Chapter 1 -- Brief history of "the beach" in Florida. Chapter 2 -- The legal geography of the beach. Chapter 3 -- The value of the property on/near the beach, despite natural hazard risk. Chapter 4 -- Capturing the beach experience. Chapter 5 -- Assessing public space along Florida beaches: NW FL case study. Chapter 6 -- Sketch mapping accessibility. Chapter 7 -- Explicit territoriality: good/bad fences. Chapter 8 -- Implied territoriality: good/bad neighbors. Chapter 9 -- Mapping the potential of conflict: transboundary viewsheds. Chapter 10 -- Conclusion: bringing it all together. .
    Abstract: This book offers a theoretical and practical exploration of the beach as space and place (i.e. territoriality) through three disciplinary lenses (Political Science, Geography, Art), utilizing the lens of territoriality and field-based participant cartographic mapping to understand better the ways in which the developed shoreline in Florida is territorialized. The book approaches the complex topic of territoriality on Florida’s beaches from two novel but related methods: participatory mapping/cartography and performance art. Both methods involve participants interacting with, perceiving, and ultimately representing feelings about a place. One method captures those feelings through the medium of the cartographic product (or a map), while the other leads to a set of symbols (flags), performance (actions in place) and visceral record (photography, sound, and journaling). Readers will gain insight into the role of political systems, ideological climates, local culture (including diverse cultures throughout the Florida state territory), and environmental history and challenges in shaping territoriality. The book will be of interest to a wide array of scholars working in coastal and land use planning topics at the intersection of geography, political science and art, including urban planners, land managers, and associated stakeholders dealing with ongoing tensions between private and public property rights on and near beaches.
    Type of Medium: Online Resource
    Pages: XIV, 100 p. 39 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030973155
    DDC: 910.285
    Language: English
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  • 53
    Keywords: Geographic information systems. ; Cartography. ; Physical geography. ; Geographical Information System. ; Cartography. ; Earth System Sciences.
    Description / Table of Contents: Chapter 1. About this book -- Part I. Concepts, data and validation -- Chapter 2. Land Use Cover mapping, modelling and validation. A background -- Chapter 3. Validation of Land Use Cover maps: a guideline -- Chapter 4. Land Use Cover Datasets: a review -- Part II. Data access and visualization -- Chapter 5. Visualization and communication of LUC data -- Chapter 6. Sample data for thematic accuracy assessment in QGIS -- Part III. Tools to validate Land Use Cover maps: a review -- Chapter 7. Basic and Multiple-Resolution Cross Tabulation to validate Land Use Cover maps -- Chapter 8. Metrics based on a Cross-Tabulation matrix to validate Land Use Cover maps -- Chapter 9. Pontius Jr. methods based on a Cross Tabulation matrix to validate Land Use Cover maps -- Chapter 10. Validation of soft maps produced by a Land Use Cover Change model -- Chapter 11. Spatial metrics to validate Land Use Cover maps -- Chapter 12. Advanced pattern analysis to validate Land Use Cover maps -- Chapter 13. Geographically Weighted methods to validate Land Use Cover maps -- Part IV. Land Use Cover datasets: a review -- Chapter 14. Global general Land Use Cover datasets with a single date,- Chapter 15. Global general Land Use Cover datasets with a time series of maps -- Chapter 16. General Land Use Cover datasets for Europe -- Chapter 17. General Land Use Cover datasets for Africa -- Chapter 18. General Land Use Cover datasets for America and Asia -- Chapter 19. Global thematic Land Use Cover datasets characterizing vegetation covers -- Chapter 20. Global thematic Land Use Cover datasets characterizing agricultural covers -- Chapter 21. Global thematic Land Use Cover datasets characterizing artificial covers -- Chapter 22. Supra-national thematic Land Use Cover datasets.
    Abstract: This open access book represents a comprehensive review of available land-use cover data and techniques to validate and analyze this type of spatial information. The book provides the basic theory needed to understand the progress of LUCC mapping/modeling validation practice. It makes accessible to any interested user most of the research community's methods and techniques to validate LUC maps and models. Besides, this book is enriched with practical exercises to be applied with QGIS. The book includes a description of relevant global and supra-national LUC datasets currently available. Finally, the book provides the user with all the information required to manage and download these datasets.
    Type of Medium: Online Resource
    Pages: XIV, 462 p. 273 illus., 226 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030909987
    DDC: 910.285
    Language: English
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  • 54
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Quantitative research. ; Environmental sciences Mathematics. ; Database management. ; Geography. ; Geographical Information System. ; Data Analysis and Big Data. ; Mathematical Applications in Environmental Science. ; Database Management System. ; Geography.
    Description / Table of Contents: Part A Basics and Computer Science: -- Modeling of Geographic Information -- Mathematics and Statistics -- Databases -- Encoding of Geographic Information -- Big Data Analytics -- Part B Geographic Information: -- Geographic Information Systems (GIS) -- Change Detection -- Geodesy -- Data Acquisition in Geographic Information Systems -- Remote Sensing -- Surveying -- Geometry and Topology -- Cartography -- Geospatial Metadata -- Standardization of Geographic Information -- Geospatial Web Services -- Geosemantic Interoperability and the Geospatial Semantic -- Registration of Geospatial Information Elements -- Security for Open Distributed Geospatial Information Systems -- Part C Applications: -- Cadastre -- Building Information Modeling -- Location Based Services -- Marine Geographic Information Systems -- Geographic Information Systems in Agriculture -- Geographic Information Systems in Defense -- Geographic Information Systems for Transportation -- Geology -- Geographic Information Systems in Energy and Utilities -- Geographic Information Systems in Health and Human Services -- Open Source Geographic Information Systems -- Smart Cities.
    Abstract: This handbook provides an exhaustive, one-stop reference and a state-of-the-art description of geographic information and its use. This new, substantially updated edition presents a complete and rigorous overview of the fundamentals, methods and applications of the multidisciplinary field of geographic information systems. Designed to be a useful and readable desk reference book, but also prepared in various electronic formats, this title allows fast yet comprehensive review and easy retrieval of essential reliable key information. The Springer Handbook of Geographic Information is divided into three parts. Part A, Basics and Computer Science, provides an overview on the fundamentals, including descriptions of databases and encoding of geographic information. It also covers the underlying mathematical and statistics methods and modeling. A new chapter exemplifies the emerging use and analysis of big data in a geographic context. Part B offers rigorous descriptions of gathering, processing and coding of geographic information in a standardized way to allow interoperable use in a variety of systems; from traditional methods such as geodesy and surveying to state-of-the-art remote sensing and photogrammetry; from cartography to geospatial web services. Discussions on geosemantic interoperability and security of open distributed geospatial information systems complete the comprehensive coverage. The final part describes a wide array of applications in science, industry and society at large, such as agriculture, defense, transportation, energy and utilities, health and human services. The part is enhanced by new chapters on smart cities and building information modeling, as well as a complete overview of the currently available open-source geographic information systems. Using standardized international terminology, in accordance with ISO/TC 211 and INSPIRE, this handbook facilitates collaboration between different disciplines and is a must have for practitioners and new comers in industry and academia.
    Type of Medium: Online Resource
    Pages: XXXIV, 969 p. 620 illus. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030531256
    Series Statement: Springer Handbooks,
    DDC: 910.285
    Language: English
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  • 55
    Keywords: Geographic information systems. ; Artificial intelligence. ; Machine learning. ; Geographical Information System. ; Artificial Intelligence. ; Machine Learning.
    Description / Table of Contents: From Representation to Geocomputation: Some Theoretical Accounts of Geographic Information Science -- On Holo-Spatial Information System -- The Virtual Geographic Environment—More than the Digital Twin of the Physical Geographical Environments -- Big Remote Sensing Data as Curves -- GIScience from the Viewpoint of Information Science -- Towards Place-based GIS -- The Bottom-up Approach and De-mapping Direction of GIS -- The Geography of Geography -- Classification and Description of Geographic Information: a Comprehensive Expression Framework -- On the Third Law of Geography -- Human Mobility and the Neighborhood Effect Averaging Problem (NEAP) -- How to Form and Answer the So What Question in GIScience -- Prospects on Causal Inferences in GIS -- Bayesian Methods for Geospatial Data Analysis.
    Abstract: This book is a collection of seminal position essays by leading researchers on new development in Geographic Information Sciences (GIScience), covering a wide range of topics and representing a variety of perspectives. The authors propose enrichments and extensions to the conceptual framework of GIScience; discuss a series of transformational methodologies and technologies for analysis and modeling; elaborate on key issues in innovative approaches to data acquisition and integration, across earth sensing to social sensing; and outline frontiers in application domains, spanning from natural science to humanities and social science, e.g., urban science, land use and planning, social governance, transportation, crime, and public health, just name a few. The book provides an overview of the strategic directions on GIScience research and development. It will benefit researchers and practitioners in the field who are seeking a high-level reference regarding those directions.
    Type of Medium: Online Resource
    Pages: X, 381 p. 69 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811938160
    DDC: 910.285
    Language: English
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  • 56
    Keywords: Geographic information systems. ; Data mining. ; Cooperating objects (Computer systems). ; Machine learning. ; Computational intelligence. ; Geographical Information System. ; Data Mining and Knowledge Discovery. ; Cyber-Physical Systems. ; Machine Learning. ; Computational Intelligence.
    Abstract: This book is the proceeding of the 1st International Conference on Distributed Sensing and Intelligent Systems (ICDSIS2020) which will be held in The National School of Applied Sciences of Agadir, Ibn Zohr University, Agadir, Morocco on February 01-03, 2020. ICDSIS2020 is co-organized by Computer Vision and Intelligent Systems Lab, University of North Texas, USA as a scientific collaboration event with The National School of Applied Sciences of Agadir, Ibn Zohr University. ICDSIS2020 aims to foster students, researchers, academicians and industry persons in the field of Computer and Information Science, Intelligent Systems, and Electronics and Communication Engineering in general. The volume collects contributions from leading experts around the globe with the latest insights on emerging topics, and includes reviews, surveys, and research chapters covering all aspects of distributed sensing and intelligent systems. The volume is divided into 5 key sections: Distributed Sensing Applications; Intelligent Systems; Advanced theories and algorithms in machine learning and data mining; Artificial intelligence and optimization, and application to Internet of Things (IoT); and Cybersecurity and Secure Distributed Systems. This conference proceeding is an academic book which can be read by students, analysts, policymakers, and regulators interested in Distributed Sensing, Smart Network approaches, Smart Cities, IoT Applications, and Intelligent Applications. It is written in plain and easy language, and describes new concepts when they appear first so that a reader without prior background of the field finds it readable. The book is primarily intended for research students in sensor networks and IoT applications (including intelligent information systems, and smart sensors applications), academics in higher education institutions including universities and vocational colleges, policy makers and legislators. .
    Type of Medium: Online Resource
    Pages: X, 865 p. 314 illus., 209 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030642587
    Series Statement: Studies in Distributed Intelligence,
    DDC: 910.285
    Language: English
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  • 57
    Keywords: Geographic information systems. ; Natural disasters. ; Environmental geography. ; Physical geography. ; Cartography. ; Earth sciences. ; Geographical Information System. ; Natural Hazards. ; Integrated Geography. ; Physical Geography. ; Cartography. ; Earth Sciences.
    Description / Table of Contents: Chapter 1. Introduction to Spatial Modeling of Flood Risk and Hazard: Societal Implication -- Chapter 2. Flood Susceptibility Mapping Using Morphometric Techniques and GIS -- Chapter 3. Palaeohydrologic Estimates of Flood Discharge of Lower Ramganga River Catchment of Ganga Basin, India Using Slackwater Deposits -- Chapter 4. Flood Risk Zone Identification Using Ground Based Observation and Geospatial Technology -- Chapter 5. Dynamics River Networks and Determination of the Flood Potential in Lower Brahmaputra Valley Using Geoinfromatics -- Chapter 6. Flood Vulnerability Assessment Using AHP and Frequency Ratio Techniques -- Chapter 7. Application of Hybrid Machine Learning Algorithms for Flood Susceptibility Modelling -- Chapter 8. Flash Flood Susceptibility Mapping Using GIS Based AHP Method -- Chapter 9. GIS Based Hydrological and Hydraulic Models to Forecast River Flood Risks and Proposition of Management Measures -- Chapter 10. Large Scale Human Intervention and Estimation of Flood Susceptibility Applying Frequency Ratio Model -- Chapter 11. Flood Induced Transport Infrastructural Losses in India: Regional Assessments -- Chapter 12. Rural-Urban Differential in Flood Vulnerability and Community Preparedness for Flood Management Strategies -- Chapter 13. Application of Geospatial Techniques for Urban Flood Management: A Review.
    Abstract: Floods and flash floods with hydro-meteorological and tropical cyclones are the some of the most devastating natural disasters causing massive damages to natural and man-made features. Flood hazards are a major threat to human life, properties (agricultural area, yield production, building and homes) and infrastructures (bridges, roads, railways, urban infrastructures, etc). Flood hazards susceptibility mapping (risk assessment) and modelling is an essential step for early warning systems, emergency services, prevention and mitigation of future environmental and social hazards and implementation of risk management strategies. Due to the lack of proper information, technology-based policies and strategies, mapping and modelling can often not be implemented to the best possible level. Geo-spatial techniques have enjoyed rising interest in recent decades among the earth environmental and social sciences research communities for their powerful ability to solve and understand various complex problems and develop novel approaches toward sustainable earth and human society. By linking geo-spatial computational intelligence techniques with societal and environmental-oriented problems, this book demonstrates geospatial technology approaches to data mining techniques, data analysis, modelling, risk assessment and visualization and management strategies in different aspects of flood hazards. We believe that a diverse group of academics, scientists, geographers, hydrologist, remote sensing and GIS expertise, environmentalists, meteorologists and computing experts with a common interest in geospatial sciences within the earth environmental sciences and humanistic and social sciences will find this book to be of great value.
    Type of Medium: Online Resource
    Pages: XIX, 238 p. 120 illus., 110 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030945442
    Series Statement: GIScience and Geo-environmental Modelling,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Big data. ; Data mining. ; Architecture. ; Design. ; Urban ecology (Biology). ; Geographical Information System. ; Big Data. ; Data Mining and Knowledge Discovery. ; Architecture. ; Design. ; Urban Ecology.
    Description / Table of Contents: The introduction to informed urban environments -- The bigger picture en route to informed urban environments -- How we see now: Traversing a data-mosaic -- The role of information modelling and computational ontologies to support the design, planning and management of urban environments: Current status and future challenges -- Urban adaptation – Insights from information physics and complex system dynamics -- Decoding cool urban forms: Using open data to build a dialogue between microclimate and configurational morphology in urban environments -- From Amsterdam to New Amsterdam to Amsterdam: How urban mobility shapes cities -- urban microclimate spatiotemporal mapping: A method to evaluate thermal comfort availability in urban ecosystems -- Urban ecosystems and nature-based solutions: The role of data in optimizing the provision of ecosystem services -- Smart urban forestry: Is it the future?- Big data and decision support in rural and urban agriculture.
    Abstract: This book collects ground-breaking works on the actual and potential impact of big data and data-integrated design for resilient urban environments, including human- and ecology-centred perspectives. Comprehending and designing for urban social, demographic and environmental change is a complex task. Big data, data structuring, data analysis (i.e. AI and ML) and data-integrated design can play a significant role in advancing approaches to this task. The themes presented in this book include urban adaptation, urban morphology, urban mobility, urban ecosystems, urban climate, urban ecology and agriculture. Given the compound nature of complex sustainability problems, most chapters address the correlation between several of these themes. The book addresses practitioners, researchers and graduate students concerned with the rapidly increasing role of data in developing urban environments.
    Type of Medium: Online Resource
    Pages: XI, 195 p. 39 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031038037
    Series Statement: The Urban Book Series,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Medical sciences. ; Geography. ; Quantitative research. ; Geographical Information System. ; Health Sciences. ; Regional Geography. ; Data Analysis and Big Data.
    Description / Table of Contents: Chapter 1. How covid changed our daily geographies -- Chapter 2. Geography of the pandemic -- Chapter 3. Defining first- and second-order impacts through maps -- Chapter 4. Quantitative geographical approaches in COVID-19 research: A review on first- and second-order impacts -- Chapter 5. COVID-19’s impact on geospatial data: ethics and values -- Chapter 6. The City and the Pandemic - the Cities’ COVID Mitigation Mapping (C2M2) Program -- Chapter 7. Improving access to health services in Mongolia via open data during and beyond the COVID-19 pandemic -- Chapter 8. The inequities in the U.S. during the COVID-19 pandemic -- Chapter 9. The Latine community and COVID-19: nuances, experiences, and data -- Chapter 10. An overview of the impact of COVID-19 in Nepal’s international tourism industry -- Chapter 11. Data and dashboards for measuring the social impact of COVID-19 in African cities -- Chapter 12. COVID-19 and domestic violence complaints in Quito, Ecuador: temporal and spatial patterns and drivers -- Chapter 13. Mapping COVID-19: Should it be based on the incidence rate? A case study in China -- Chapter 14. Regional patterns of the pandemic: a view from Aotearoa New Zealand -- Chapter 15. Aboriginal and Torres Strait Islander peoples & the COVID-19 pandemic: a spatial and place-based analysis -- Chapter 16. Impacts of COVID-19 pandemic lockdown on the livelihoods of male commercial Boda-Boda motorists in Uganda -- Chapter 17. Geospatial techniques for mapping the spatial trajectories of COVID-19 -- Chapter 18. Digital geographies and digital surveillance technologies: power and space in the Italian society under control for public health -- Chapter 19. Resilience amid uncertainty: COVID-19 pandemic, the urban informal sector, and livelihoods in sub-Saharan Africa -- Chapter 20. Freshwater Resources and COVID-19 -- Chapter 21. Preventing pandemics: earth observations for One Health -- Chapter 22. Enabling Accelerated Research in Times of Need: The National Science Foundation’s Response to COVID-19 in 2020 -- Chapter 23. Conclusion - The consequences of COVID-19 – What’s next?.
    Abstract: This volume of case studies focuses on the geographies of COVID-19 around the world. These geographies are located in both time and space concentrating on both first- and second-order impacts of the COVID-19 pandemic. First-order impacts are those associated with the immediate response to the pandemic that include tracking number of deaths and cases, testing, access to hospitals, impacts on essential workers, searching for the origins of the virus and preventive treatments such as vaccines and contact tracing. Second-order impacts are the result of actions, practices, and policies in response to the spread of the virus, with longer-term effects on food security, access to health services, loss of livelihoods, evictions, and migration. Further, the COVID-19 pandemic will be prolonged due to the onset of variants as well as setting the stage for similar future events. This volume provides a synopsis of how geography and geospatial approaches are used to understand this event and the emerging “new normal.” The volume's approach is necessarily selective due to the global reach of the pandemic and the broad sweep of second-order impacts where important issues may be left out. However, the book is envisioned as the prelude to an extended conversation about adaptation to complex circumstances using geospatial tools. Using case studies and examples of geospatial analyses, this volume adopts a geographic lens to highlight the differences and commonalities across space and time where fundamental inequities are exposed, the governmental response is varied, and outcomes remain uncertain. This moment of global collective experience starkly reveals how inequality is ubiquitous and vulnerable populations – those unable to access basic needs – are increasing. This place-based approach identifies how geospatial analyses and resulting maps depict the pandemic as it ebbs and flows across the globe. Data-driven decision making is needed as we navigate the pandemic and determine ways to address future such events to enable local and regional governments in prioritizing limited resources to mitigate the long-term consequences of COVID-19.
    Type of Medium: Online Resource
    Pages: XXXI, 300 p. 57 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031117756
    Series Statement: Global Perspectives on Health Geography,
    DDC: 910.285
    Language: English
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  • 60
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Physical geography. ; Control engineering. ; Robotics. ; Automation. ; Human ecology Study and teaching. ; Human geography. ; Geographical Information System. ; Physical Geography. ; Control, Robotics, Automation. ; Environmental Studies. ; Human Geography.
    Description / Table of Contents: Section 1 – sUAS Basics -- Introduction and outline for book – Konsoer, Leitner, Lewis -- Provide brief history of sUAS and the rapid technological advancements in recent years that have led to drone revolution and close range remote sensing -- Outline of book and intended uses as both a collection of specific research topics in geography and as a teaching tool -- Rules and Regulations for sUAS use in the United States (and/or globally, selected countries?) -- FAA regulations -- Essentials of proper and safe sUAS use -- sUAS Ethics and other considerations (privacy issues) -- Communicating Science with sUAS -- Section 2 – Applications in Human Geography -- Crime Geography (e.g., security, surveillance/monitoring, etc.) -- Sociocultural Geography (e.g., monitoring cultural resources) -- 3D Mapping -- Section 3 – Applications in Physical Geography -- Geomorphology -- Climatology -- Biogeography (e.g., precision agriculture, habitat monitoring, etc.) -- Section 4 – Applications in Interdisciplinary Research -- Environmental Geography (e.g., water quality, algae, land use changes) -- Mississippi River Delta Archaeological Mitigation (MRDAM) (e.g., geomorphology and archaeology – Konsoer et al) -- Disaster Science Management (e.g. search and rescue operations, damage assessment).
    Abstract: The use of small unoccupied aerial systems (sUAS) for acquiring close-range remotely sensed data has substantially increased in the past 5 years. A primary focus of early research was on physical systems and photogrammetric techniques. However, as sUAS technology continues to improve and more sophisticated payloads are utilized, such as lidar and multispectral cameras, applications have expanded to nearly all subdisciplines within Geography. This edited volume is intended to showcase the various ways in which sUAS are used in geographic research, including geomorphology, environmental and hazard monitoring, biogeography, and urban and sociocultural geography.
    Type of Medium: Online Resource
    Pages: VI, 331 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031019760
    Series Statement: Geotechnologies and the Environment, 24
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Cartography. ; Geography. ; Geographical Information System. ; Cartography. ; Geography. ; Regional Geography.
    Description / Table of Contents: Assessment on the Distribution and Accessibility to Green Spaces in Mexico’s Most Populated Metropolitan Zones -- Geomatics Assessment of Water Resources in a Transboundary Basin -- Geospatial Analysis of Clandestine Graves in Baja California: New Approaches for the Search of Missing Persons in Mexico -- The Geopolitical Repercussions of the Migration Rhetoric of Donald Trump on Mexican Anti-immigrant Speech Online: A Transdisciplinary Approach -- Spatial Analysis of a Forest Socio-Ecological System in Oaxaca, Mexico Based on the DPSIR Framework -- Fourier Transform Based Methods for Unwrapping of Sentinel-1 Interferograms -- Methodology and Relevant Results About an Area-Based Conservation Indicator of Superficial Water Bodies for the Grijalva Basin -- Social Vulnerability Analysis of Three High Mountain Villages at Pico de Orizaba Volcano, Mexico, Using PCA -- Detection of Phoradendron velutinum Implementing Genetic Programming in Multispectral Aerial Images in Mexico City -- Assessment of the Reduction of the Icesnow Coverage at the TransMexican Volcanic Belt Through Empirical Mode Decomposition on Satellite Imagery -- Forest Degradation Estimation Through Trend Analysis of Annual Time Series NDVI, NDM and NDFI (2010-2020) using Landsat images -- Estimating Importation Risk of COVID-19 in Hurricane Evacuations: A Prediction Framework Applied to Hurricane Laura in Texas -- A Dynamic Social Vulnerability Index to COVID-19 in Mexico -- Effects of COVID-19 in Mexico City: Street Robbery and Vehicle Theft Spatio-Temporal Patterns.
    Abstract: This book presents a selection of manuscripts submitted to the 2nd International Conference on Geospatial Information Sciences 2021, a virtual conference held on November 3-5, 2021. These papers were selected by the Scientific Program Committee of the Conference after a rigorous peer-review process. They represent the vast scope of the interdisciplinary research areas that characterize the Geospatial Information Sciences that is done in the discipline. It especially represents a fabulous opportunity to showcase research carried out by young Mexican researchers and showcase it to the rest of the world and enhance the growth of the sciences in the country while, at the same time, enforces them to level up with other research at the international level.
    Type of Medium: Online Resource
    Pages: XIV, 205 p. 67 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030980962
    Series Statement: Lecture Notes in Geoinformation and Cartography,
    DDC: 910.285
    Language: English
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  • 62
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Physical geography. ; Earth sciences. ; Signal processing. ; Computer vision. ; Geographical Information System. ; Fossil Fuel. ; Physical Geography. ; Earth Sciences. ; Digital and Analog Signal Processing. ; Computer Vision.
    Description / Table of Contents: Chapter 1-Electromagnetic spectral bands used for RS in HC exploration -- Chapter 2-Foundations of multi-spectral image processing -- Chapter 3-Surface elevation and surface texture from microwave radar -- Chapter 4-Surface cover from optical and thermal IR -- Chapter 5-Geomorphology and Mapping -- Chapter 6-Near-surface characteristics from optical, thermal IR and microwave radar -- Chapter 7-Basement depth and texture from radar distance anomalies -- Chapter 8-Mapping of temporal changes -- Chapter 9-Frontier exploration -- Chapter 10-Seismic planning, acquisition and data processing -- Chapter 11-Development and oilfield infrastructure planning -- Chapter 12-Geological analogs. .
    Abstract: This book provides insights into the benefits of using remote sensing data from a geoscientist's perspective, by integrating the data with the understanding of Earth's surface and subsurface. In 3 sections, the book takes a detailed look at what data explorationists use when they explore for hydrocarbon resources, assess different terrain types for planning and hazards and extract present-day geologic analogs for subsurface geologic settings. The book presents the usage of remote sensing data in exploration in a structured way by detecting individual geologic features as building blocks for complex geologic systems. This concept enables readers to build their own workflows for the assessment of complex geologic systems using various combinations of remote sensing data. Section 1 introduces readers to the foundations of remote sensing for exploration, covers various methods of image processing and studies different digital elevation and bathymetry models. Section 2 presents the concept of geomorphology as a means to integrate surface and subsurface data. Different aspects of rendering in 2D and 3D are explained and used for the interpretation and extraction of geologic features that are used in exploration. Section 3 addresses remote sensing for hydrocarbon exploration in detail, from geophysical data acquisition to development and infrastructure planning. The organization of this chapter follows an exploration workflow from regional to local modeling studying basin and petroleum system modeling as well as logistics planning of seismic surveys and near-surface modeling. Aspects of field development and infrastructure planning comprise multi-temporal and dynamic modeling. The section closes with a structured approach to extracting geologic analogs from interpreted remote sensing data. The book will be of interest to professionals and students working in exploration for hydrocarbons and water resources, as well as geoscientists and engineers using remote sensing for infrastructure planning, hazard assessment and dynamic environmental studies.
    Type of Medium: Online Resource
    Pages: LVII, 348 p. 8 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030733193
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Aerospace engineering. ; Astronautics. ; Environmental monitoring. ; Control engineering. ; Robotics. ; Automation. ; Geographical Information System. ; Aerospace Technology and Astronautics. ; Environmental Monitoring. ; Control, Robotics, Automation.
    Description / Table of Contents: Chapter 1. Unmanned Aircraft Systems and the Nordic Challenges -- Chapter 2. Applying an icing wind tunnel for drone propeller research, validation of new measurement instrument -- Chapter 3. Self-Swarming for Multi-Robot Systems Deployed for Situational Awareness -- Chapter 4. Toward Invisible Drones – An Ultra-HDR Optical Cloaking System -- Chapter 5. Long-Term Autonomy in Forest Environment using Self-Corrective SLAM -- Chapter 6. Future Possibilities and Challenges for UAV-based Imaging Development in Smart Farming -- Chapter 7. Role of Drones in Characterizing Soil Water Content in Open Field Cultivation -- Chapter 8. Ground penetrating radar mounted drones in agriculture -- Chapter 9. A minimalist approach to yield mapping of standing wheat crop with unmanned aerial vehicles -- Chapter 10. Assessment of Crop Yield Prediction Capabilities of CNN using Multisource Data.
    Abstract: This volume presents the conference proceedings from FinDrones2020. The book highlights recent developments in drone technology by experts, academicians, and entrepreneurs for applications in agriculture, forestry, and other industries. Emphasis is placed on contextualizing the conference presentations and content to Finland and the unique challenges typical to this region. The work will be of interest to academicians and professionals involved in remote sensing applications of unmanned aerial vehicles, as well as enthusiasts of drone technological developments.
    Type of Medium: Online Resource
    Pages: X, 195 p. 56 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030778606
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Natural disasters. ; Landscape ecology. ; Physical geography. ; Geographical Information System. ; Natural Hazards. ; Landscape Ecology. ; Physical Geography.
    Description / Table of Contents: Introduction -- Preface -- Section-I : Land Use Land Cover Dynamics -- Section-II: Agriculture water Management.-Section III: Water Resources Assessment and Modelling -- Section IV: Natural Disasters -- Conclusions and Recommendations.
    Abstract: This book focuses on the application of geospatial technologies to study the land use land cover (LULC) dynamics, agricultural water management, water resources assessment and modeling, and studies on natural disasters. LULC dynamics is one of the major research themes for studying global environmental change using remote sensing data. The section on LULC dynamics covers the multi-variate criteria for land use and land cover classification and change assessment in the mountainous regions. Further, LULC change detection of the Tons river basin and LULC dynamics at decadal frequency are studied to derive adaptation and mitigation strategies. Landscape-level forest disturbance modeling, together with conservation implications, is also included. The watershed management approach is necessary for comprehensive management of land and water resources of any region, where studies on multi-criteria analysis for rainwater harvesting planning and its impact on land use land cover transformations in rain-fed areas using geospatial technologies are presented in this book. The book will be useful for academics, water practitioners, scientists, water managers, environmentalists, and administrators, NGOs, researchers, and students who are actively involved in the application of geospatial technologies in LULC studies, agricultural water management and hydrological modelling and natural disasters for addressing the challenges being posed by climate change while addressing issues of food and water securities .
    Type of Medium: Online Resource
    Pages: VIII, 621 p. 251 illus., 213 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030904791
    Series Statement: Water Science and Technology Library, 103
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Agriculture. ; Environment. ; Landscape ecology. ; Human ecology Study and teaching. ; Geographical Information System. ; Agriculture. ; Environmental Sciences. ; Landscape Ecology. ; Environmental Studies.
    Description / Table of Contents: Chapter 1. Agricultural Information Needs and Research Priorities for Remote Sensing in South and Southeast Asian Countries (Krishna Vadrevu, Thuy Le Toan, Shibendu Ray and Chris Justice) -- Part I: International, Regional and National Programs in Agriculture -- Chapter 2. South/Southeast Asia Research Initiative and Agricultural Research Projects (Krishna Vadrevu) -- Chapter 3. The NASA Harvest program on Agriculture and Food Security (Inbal Becker-Reshef, Varaprasad Bandaru, Brian Barker,Sylvain Coutu, Jillian M Deines, Bradley Doorn, Gary Eilerts, Belen Franch, Antonio Sanchez Galvez, Mehdi Hosseini1, Michael Humber, Greg Husak, Kaiyu Guan, Christina Justice, John Keniston, Hannah Kerner, Mary Mitkish, Kara Mobley, Blake Munshell, Catherine Nakalembe, Estefania Puricelli, Ritvik Sahajpal, Sergii Skakun, Eric Vermote, Alyssa Whitcraft, Matthew Hansen, Bill Salas, and Christopher Justice) -- Chapter 4. Asia-RiCE: Collaborative framework for Rice Crop Management in Asia (Shinichi Sobue, and Lal Samarakoon, Matthew Steventon, Kei Oyoshi, Thuy Le Toan) -- Chapter 5. Rice Growth Outlook using Satellite-Based Information in Southeast Asia (Kei Oyoshi, Shinichi Sobue, and Shoji Kimura) -- Chapter 6. RIICE – The service and its operational use (Francesco Holecz, Tri Setiyono, Massimo Barbieri, Francesco Collivignarelli, Luca Gatti, Michael Anthony, Renaud Mathieu, Emma Quicho, Aileen Maunahan, Sushree Satapathy, Deiveegan Murugesan, Ponnurangam Ganesan, Alice Laborte, Mary Rose Mabalay, Jovino de Dios, Eduardo Jimmy Quilang, Men Sothy, Pich Rothana, Vang Seng, Ngin Chhay, Chharom Chin, Phuong Do Minh, Hung Bui Vang, Vo Quoc Tuan, Tuong Chi Quang, Vo Quang Minh, Ninh Nguyen Hong, Sellaperumal Pazhanivela, Bernard Zaugg) -- Chapter 7. The Philippine Rice Information System (PRiSM): An operational monitoring and information system on rice (Mary Rose Mabalay, Jeny Raviz, Elmer Alosnos, Massimo Barbieri, Emma Quicho, Jesiree Elena Ann Bibar, Mabel Barroga, Meriam Coñado, Pristine Mabalot, Jean Rochielle Mirandilla, Arturo Arocena, Juanito Maloom, Gerald Bello, Ederlina Cariño, Gina de Mesa, Norlyn Detoito, Harvey Gonzaga, Nonilon Martin, Mitzi Philline Tejada, Mary Jane Vives, Marjie Lastimoso, Darlynne Kaye Bumagat, Henry Cayaban, Michael Barroga, Ruvicyn Bayot, Abel Melquiades Callejo, Neale Marvin Paguirigan, Mary Anne Gutierrez, Gene Christhopher Romuga, Frances Grace Amanquiton, Janica Gan, Ethel Princess Banasihan, Creigton Czar Guevarra, Arnel Rala, Hilario Yonson, Michael Malonzo, Glorie Belle Berja, Consolacion Diaz, Luis Alejandre Tamani, Ronald Gregory Roces, Sonia Asilo, Jovino de Dios, Tri Deri Setiyono, Francesco Holecz, Eduardo Jimmy Quilang, and Alice Laborte) -- Chapter 8. An Initiation of National Institute for Precision Agriculture Research Network: A case of Thailand Research Fund and Thailand Science Research and Innovation (Attachai Jintrawet, Prapaporn Khopaibool, Thongchai Suwansichon) -- Part II: Crop Mapping, Monitoring, Yield and Water Resources -- Chapter 9. Varietal Discrimination, Acreage Estimation and Yield Prediction of Basmati Aromatic Rice in North-Western India Using Satellite Data (Dharmesh Verma, A. N. Singh, Manik H. Kalubarme, G.P. Saroha, Ritesh Sharma and Brajendra) -- Chapter 10. Mapping Smallholder Yields Using Planet and Sentinel-2 Satellite Data (Meha Jain, Weiqi Zhou, Ambica Paliwal) -- Chapter 11. A Data-analytical way of estimating Rice crop Yield: Economic and Water related causative factors (Nilabja Ghosh, M. Rajeshwor, Alka Singh, Satarupa Chakravarty) -- Chapter 12. Rice Monitoring in Southeast Asia Using Earth Observation Satellite Data (Kei Oyoshi, Lal Samarakoon, Shin-chi Sobue, Sotheavy Meas, Men Sothy, Shoji Kimura, Rizatus Shofiyati, Tanita Suepa, Kanjana Koedkurang, Yootthapoom Potiracha6,, Sutinee Sihirunwong, Patiwet Chalearmpong, Panu Nuangjumnong, Damrongrit Niammuad, and Soravis Supavetch, Phung Hoang-Phi,Nguyen Lam-Dao,and Thuy Le Toan) -- Chapter 13. Crop LAI and biomass estimation from different polarization modes of simulated NISAR data (Dipankar Mandal, Vineet Kumar, Avik Bhattacharya and Y. S. Rao) -- Chapter 14. Pixel-based evaluation of rice production and related greenhouse gas emissions in the Mekong Delta integrating SAR data and ground observations (Hironori Arai, Wataru Takeuchi, Kei Oyoshi, Lam Dao Nguyen, Tamon Fumoto, Kazuyuki Inubushi and Thuy Le Toan) -- Chapter 15. The utilization of satellite data to support wet season rice production policy in Thailand: A review of practices and opportunities (Chitnucha Buddhaboon, Panu Neungchumnong, Thewin Kaeomuangmoon and Attachai Jintrawet) -- Chapter 16. Productivity, damages, and losses of rice in Cambodia: past, present and future trends in the Mekong and Tonle Sap regions (Serey Sok, Hoeurn Cheb, Nyda Chhinh and Pheakdey Nguonphan) -- Chapter 17. Rice growth stage monitoring and yield estimation in the Vietnamese Mekong Delta using multi-temporal Sentinel-1 data (Phung Hoang-Phi, Nguyen Lam-Dao, Vu Nguyen-Van-Anh, Thanh Nguyen-Kim, Thuy Le Toan, and Tien Pham-Duy) -- Chapter 18. Agricultural Drought Assessment using Remote Sensing, with special emphasis on India (S. S. Ray, Shalini Saxena, K. Choudhary, Preeti Tahlani and Krishna Vadrevu) -- Chapter 19. Role of remote sensing in assessing total water storage and evapotranspiration for croplands in the Mekong river basin (Venkataramana Sridhar, Syed Azhar Ali) -- Part III: Prediction and Modeling -- Chapter 20. Random forests for early rice yield prediction from time series of remote sensed data (Nguyen-Thanh Son, Chi-Farn Chen, Cheng-Cru Chen) -- Chapter 21. Assessment of Climate Change Impact on Rice production over South and Southeast Asia under CMIP6 climate scenarios (Tzu-Shun Lin and Atul K Jain) -- Chapter 22. Application of Geo-CropSim framework for Rainfed Sugarcane Yield Assessment in Thailand (Varaprasad Bandaru, Pallavi Cherumalli, Sergii Skakun, Kristofer Lasko, Sukunya Yampracha) -- Chapter 23. Crop yield assessment of smallholder farms using remote sensing and simulation modeling (Vinay Kumar Sehgal, Debasish Chakraborty, Rajkumar Dhakar, Joydeep Mukherjee, Rabi Narayan Sahoo) -- Part IV: Agricultural Land Cover/Land Use Changes -- Chapter 24. Agricultural intensity assessment in Punjab India using food security metrics and remote sensing data (Krishna Vadrevu, Emily Casadaban, Aditya Eaturu, Samuel Amborski and Sumalika Biswas) -- Chapter 25. Agricultural intensity assessment in Punjab India using food security metrics and remote sensing data (Bhavani P, Ripan Das, Mariam Jamilah, Vijay P.Kanawade, Chandrashekhar Biradar and P.S. Roy) -- Chapter 26. Nexus of Urbanization and Changes in Agricultural Land in Bangladesh (Mst. Ilme Faridatul, Md. Sarfaraz Gani Adnan and Ashraf Dewan) -- Chapter 27. The Kandyan Home Garden – Sustainable Agricultural Ecosystem in Sri Lanka (A.R. Gunawardena and T.T. Fernando) -- Chapter 28. Agricultural transformation, and deforestation in Shan State, Myanmar (Sumalika Biswas and Krishna Prasad Vadrevu) -- Chapter 29. Agricultural fires in South Asian Countries and Implications (Krishna Vadrevu, Emily Casadaban, Aditya Eaturu and Sumalika Biswas) -- Chapter 30. Agricultural Land-Use Trends in Vietnam 1990 – 2020 (Stephen J. Leisz, Nghiem Thi Tuyen, Ngo The An, Nong Duong, Nguyen Thi Bich Yen) -- Chapter 31. Scenario-Based Land-Cover/Land-Use Change Modeling of Future Agricultural Land Conversion in Dong Thap, Vietnam (Keelin Haynes, Jessica L. McCarty, Stanley W. Toops, Bui Thi Minh Ha, Jarrod W. Brown, Peter Potapov, Svetlana Turubanova, Quyen Nguyen, Peou Touch, and Justin J. Fain) -- Chapter 32. Extreme Development of Dragon Fruit Agriculture with Nighttime Lighting in Southern Vietnam (Shenyue Jia, Son V. Nghiem, Seung-Hee Kim, Laura Krauser, Andrea E. Gaughan, Forest R. Stevens, Menas Kafatos, and Khanh D. Ngo) -- Chapter 33. Agricultural Land Use/Cover Changes in the Vientiane, Laos (Chittana Phompila, Vongphet Sihapanya, Bakham Chanthavong, Sithong Thongmanivong, Phung Van Khoa, Keigo Noda and Krishna Prasad Vadrevu) -- Chapter 34. Color Features Based Model for Land Cover Identification and Agriculture Monitoring with Satellite Images (Shruti Gupta and Dharmendra Singh) -- Index.
    Abstract: This book sheds new light on the remote sensing of agriculture in South/Southeast Asian (S/SEA) countries. S/SEA countries are growing rapidly in terms of population, industrialization, and urbanization. One of the critical challenges in the region is food security. In S/SEA, although total food production and productivity have increased in previous decades, in recent years, the growth rate of food production has slowed down, mostly due to land use change, market forces and policy interventions. Further, the weather and climate systems in the region driven primarily by monsoon variability are resulting in droughts or flooding, impacting agricultural production. Therefore, monitoring crops, including agricultural land cover changes at regular intervals, is essential to predict and prepare for disruptions in the food supply in the S/SEA countries. The current book captures the latest research on the remote sensing of agricultural land cover/ land use changes, including mapping and monitoring crops, crop yields, biophysical parameter retrievals, multi-source data fusion for agricultural applications, and chapters on decision making and early warning systems for food security. The authors of this book are international experts in the field, and their contributions highlight the use of remote sensing and geospatial technologies for agricultural research and applications in South/Southeast Asia.
    Type of Medium: Online Resource
    Pages: XXVII, 617 p. 234 illus., 217 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030923655
    DDC: 910.285
    Language: English
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Quantitative research. ; System theory. ; Public health. ; Urban economics. ; Geographical Information System. ; Data Analysis and Big Data. ; Complex Systems. ; Public Health. ; Urban Economics.
    Description / Table of Contents: Introduction: Spatial Big Data and Urban Analytics -- Preferential Home Search in Urban Settings -- Air Quality Dynamics and Urban Heat Island effects during COVID-19 -- Mass Rapid Transit and Population Dynamics during Covid-19 in Singapore -- A Geospatial analysis of Tweets during Post-Circuit Breaker in Singapore -- Space-Time Analytics of New York City Shooting Incidents -- Spatial and Temporal patterns of Tourist Source Market Emissiveness: A Study of Shanghai, China -- Spatial Perspective of Crime Patterns in Chicago amid Covid-19 -- Geospatial analysis of Grab Trips in Singapore -- Ecological Vulnerability of Nyingchi, Tibet.
    Abstract: This book highlights advanced applications of geospatial data analytics to address real-world issues in urban society. With a connected world, we are generating spatial at unprecedented rates which can be harnessed for insightful analytics which define the way we analyze past events and define the future directions. This book is an anthology of applications of spatial data and analytics performed on them for gaining insights which can be used for problem solving in an urban setting. Each chapter is contributed by spatially aware data scientists in the making who present spatial perspectives drawn on spatial big data. The book shall benefit mature researchers and student alike to discourse a variety of urban applications which display the use of machine learning algorithms on spatial big data for real-world problem solving.
    Type of Medium: Online Resource
    Pages: XVIII, 187 p. 106 illus., 95 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811676499
    Series Statement: Advances in 21st Century Human Settlements,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Environmental management. ; Climatology. ; Natural disasters. ; Database management. ; Geographical Information System. ; Environmental Management. ; Climate Sciences. ; Natural Hazards. ; Database Management.
    Description / Table of Contents: Spatio-temporal variability of channel planform dynamics in response to spatial expansion of brick kilns: a case study of the downstream course of Ichamati River, West Bengal, India -- Assessment of replenishable groundwater resource and integrated water resource planning for sustainable agriculture -- Spatial prediction of flood frequency analysis in a semi-arid zone: A case study from the Seyad basin (Guelmim Region, Morocco) -- Geospatial modeling in the assessment of environmental resources for sustainable water resource management in a Gondia district, India -- Hydrochemical characteristics of groundwater-assessment of saltwater intrusion along Krishna Godavari Delta Region, Andhra Pradesh, India -- Micro level planning for integrated natural resources management and sustainable development: an approach through a micro watershed using geospatial technology -- Ecohydrological perspective for environmental degradation of lakes and wetlands in Delhi -- Prioritization and quantitative assessment of Dhundsir Gad using RS and GIS: implications for watershed management, planning and conservation, Garhwal Himalaya, Uttarakhand -- Assessment of groundwater potential zones and resource sustainability through Geospatial Techniques: a case study of Kamina sub-watershed of Bhima River Basin, Maharashtra, India -- Morphometric analysis of Damodar River sub-watershed, Jharkhand, India, using remote sensing and GIS techniques -- The increasing inevitability of IOT in remote disaster monitoring applications -- Countering challenges of smart cities mission through participatory approach -- Urban growth modelling and prediction of land use land cover change over Nagpur city, India using Cellular automata approach -- Slum categorization for efficient development plan - a case study of Udhampur city, J&K using Remote sensing and GIS -- Urban growth trend analysis using Shannon Entropy approach – A case study of Dehradun City of Uttarakhand, India -- Geospatial approach for mapping of significant land use / land cover changes in Andhra Pradesh -- Assessing the impact of Delhi metro network towards urbanization of Delhi-NCR -- Analysis of urban heat island effect in the Rajkot city using Geospatial Techniques -- Multi spectral remote sensing for urban planning and development -- Analysis Of urban green spaces using geospatial techniques-a case study of Vijayawada urban local body Andhra Pradesh, India -- Magnetic susceptibility and heavy metals contamination in agricultural soil of Kopargaon Area, Ahmadnagar District, Maharashtra, India.
    Abstract: Geospatial technology is a combination of state-of-the-art remote sensing and technology for geographic information systems (GIS) and global navigation satellite systems (GNSS) for the mapping and monitoring of landscapes and environment. The main thrust of using geospatial technology is to understand the causes, mechanisms, and consequences of spatial heterogeneity, while its ultimate objective is to provide a scientific basis for developing and maintaining ecologically, economically, and socially sustainable landscapes. This book presents new research on the interdisciplinary applications of geospatial technology for identification, assessment, monitoring, and modelling issues related to landscape, natural resources, and environmental management. The book specifically focuses on the creation, collection, storage, processing, modelling, interpretation, display, and dissemination of spatio-temporal data, which help to resolve environmental management issues including ecosystem change, resource utilization, land use management, and environmental pollution. The positive environmental impacts of information technology advancements with regard to global environmental and climate change are also discussed. The book addresses the interests of a wide spectrum of readers who have a common interest in geospatial science, geology, water resource management, database management, planning and policy making, and resource management.
    Type of Medium: Online Resource
    Pages: XVII, 430 p. 203 illus., 193 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811673733
    Series Statement: Advances in Geographical and Environmental Sciences,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Database management. ; Education. ; Regional economics. ; Spatial economics. ; Application software. ; Geographical Information System. ; Database Management. ; Education. ; Regional and Spatial Economics. ; Computer and Information Systems Applications.
    Description / Table of Contents: Chapter 1. Three Scales of the Spatial University -- Chapter 2. U-Spatial: Nexus of the Spatial University -- Chapter 3. Spatial university for service and support -- Chapter 4. Spatial thinking and learning -- Chapter 5. Spatial science and research -- Chapter 6. Future of the Spatial University.
    Abstract: This volume discusses the concept of The Spatial University as part of the broad growth of spatial science and the need for spatial infrastructure in colleges and universities. The book centers on the development of U-Spatial, the spatial science infrastructure at the University of Minnesota that offers a range of spatial activities and services, including data access, training, and community building. Against a backdrop of the changing nature of research, teaching, and service in higher education, the story of U-Spatial anchors a broader discussion of what it means to be a spatial university. This narrative framing demonstrates—with specific examples—the importance of institutions offering dedicated spatial research infrastructure. In six chapters, the text explores the importance of spatial thinking, learning, and research for student and researcher success. The volume offers lessons that are applicable far beyond the University of Minnesota to apply to a broad array of domains and institutional specializations. The book will be useful to students, researchers, and policymakers concerned with how institutions can encourage spatial research, teaching, and service. It will also appeal to researchers and practitioners interested in broader uses of spatial science. This book shows how GIS can transform a university, speaking to the need for leadership in higher education around the power of bringing everything together using spatial and geographic concepts. Jack Dangermond Co-Founder and President, Esri.
    Type of Medium: Online Resource
    Pages: XIII, 118 p. 18 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030928476
    DDC: 910.285
    Language: English
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Cartography. ; Human geography. ; Geographical Information System. ; Cartography. ; Human Geography.
    Description / Table of Contents: - Geospatial Machine Learning in Urban Areas: Challenges and Prospects -- Exploratory Analysis and Transformation for Remotely-Sensed Imagery -- Mapping Urban Land Cover using Multi-seasonal Sentinel-2 Imagery, Spectral and Texture Indices -- Mapping Urban Land Cover using Multi-seasonal Sentinel-1 Imagery and Texture Indices -- Improving Urban Land Cover Mapping -- Land Cover Classification Accuracy Assessment -- Appendix.
    Abstract: This book introduces remotely sensed image processing for urban areas using optical and synthetic aperture radar (SAR) data and assists students, researchers, and remote sensing practitioners who are interested in land cover mapping using such data. There are many introductory and advanced books on optical and SAR remote sensing image processing, but most of them do not serve as good practical guides. However, this book is designed as a practical guide and a hands-on workbook, where users can explore data and methods to improve their land cover mapping skills for urban areas. Although there are many freely available earth observation data, the focus is on land cover mapping using Sentinel-1 C-band SAR and Sentinel-2 data. All remotely sensed image processing and classification procedures are based on open-source software applications such QGIS and R as well as cloud-based platforms such as Google Earth Engine (GEE). The book is organized into six chapters. Chapter 1 introduces geospatial machine learning, and Chapter 2 covers exploratory image analysis and transformation. Chapters 3 and 4 focus on mapping urban land cover using multi-seasonal Sentinel-2 imagery and multi-seasonal Sentinel-1 imagery, respectively. Chapter 5 discusses mapping urban land cover using multi-seasonal Sentinel-1 and Sentinel-2 imagery as well as other derived data such as spectral and texture indices. Chapter 6 concludes the book with land cover classification accuracy assessment.
    Type of Medium: Online Resource
    Pages: XI, 119 p. 103 illus., 90 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811651496
    Series Statement: Springer Geography,
    DDC: 910.285
    Language: English
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    Keywords: Geographic information systems. ; Natural disasters. ; Geology. ; Computational intelligence. ; Geographical Information System. ; Natural Hazards. ; Geology. ; Computational Intelligence.
    Description / Table of Contents: Chapter 1 -- Introduction to Part I: Geo-physical Hazards -- Chapter 2-Determination of the Probabilities of Landslide Events -A Case Study -- Chapter 3-Geoinformatics based analysis of landslide stability - A Case Study -- Chapter 4-Land Degradation and Desertification- A Case Study. Chapter 5 -- River bank erosion mapping using GIS techniques -- Chapter 6-Geo-spatial modeling of Potential soil erosion estimation for better conservation planning -- Chapter 7-Vulnerability and Risk Assessment of the Bengal Coast, India- a GIS approach -- Chapter 8-Seismic hazard, and vulnerability of assessment for the earthquake scenario-A case study -- Chapter 9-Geo-spatial techniques for mapping, monitoring and modeling shoreline to support coastal risk management -- Chapter 10-Introduction to Part II: Hydro-meteorological Hazards -- Chapter 11-Flood susceptibility analysis based on GIS frequency ratio model -- Chapter 12-Meteorological and agriculture drought monitoring –GIS based approach -- Chapter 13-Geospatial technology and agricultural water resources management -- Chapter 14-Land-Use Suitability Modeling for Agricultural Sustainability -- Chapter 15-Recent trends in climate adaptive water resources management -- Chapter 16-GIS based Spatial analysis on flood modeling - A case study -- Chapter 17-Investigating Vulnerability of Ground Water using AHP and GIS Techniques: A Study -- Chapter 18-Flood Risk zone identification using RS & GIS Techniques -- Chapter 19-Groundwater quality delineation based on Fuzzy Comprehensive Assessment Method -- Chapter 20-Introduction to Part III: Bio-physical Hazards -- Chapter 21-Forest Fire Geo knowledge based Modeling using GIS -- Chapter 22-GI based modelling for wildland fire risk assessment -- Chapter 23-Distribution of Urban Crime Analysis Using GPS, and GIS techniques -- Chapter 24-Analysis of Poverty allocation using Geoinformatics -- Chapter 25-Risk and hazards mapping of Social-economic vulnerability Using GIS techniques.
    Abstract: The book demonstrates the geospatial technology approach to data mining techniques, data analysis, modeling, risk assessment, visualization, and management strategies in different aspects of natural and social hazards. This book has 25 chapters associated with risk assessment, mapping and management strategies of environmental hazards. It covers major topics such as Landslide Susceptibility, Arsenic Contaminated Groundwater, Earthquake Risk Management, Open Cast Mining, Soil loss, Flood Susceptibility, Forest Fire Risk, Malaria prevalence, Flood inundation, Socio-Economic Vulnerability, River Bank Erosion, and Socio-Economic Vulnerability. The content of this book will be of interest to researchers, professionals, and policymakers, whose work involves environmental hazards and related solutions.
    Type of Medium: Online Resource
    Pages: XIX, 588 p. 201 illus., 173 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030751975
    Series Statement: Advances in Geographic Information Science,
    DDC: 910.285
    Language: English
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    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Bioinformatics. ; Immunology. ; Cancer Biology. ; Computational and Systems Biology. ; Immunology.
    Description / Table of Contents: 1. Introduction: Introduction of lipids, lipid metabolism and tumor immunity -- 2. ipid metabolism and lipidomics -- 3. Applications of lipidomics in tumour immunity.-4. Overview: Lipid metabolism in tumour microenvironment -- 5. Lipid metabolism in cancer cells -- 6. Lipid metabolism in tumour-associated NK -- 7. Lipid metabolism in tumour-associated macrophages -- 8. Lipid metabolism in tumour-associated MDSCs -- 9. Lipid metabolism in tumour-associated fibroblasts -- 10. Lipid metabolism in tumour-associated B cells -- 11. Lipid metabolism in tumour-infiltrating T cells -- 12. Lipid metabolism and angiogenesis -- 13. Lipid metabolism and tumor antigen-presenting -- 14. Lipid metabolism and immune checkpoints.
    Abstract: This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery. .
    Type of Medium: Online Resource
    Pages: XI, 211 p. 24 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813367852
    Series Statement: Advances in Experimental Medicine and Biology, 1316
    DDC: 571.978
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030471897
    Series Statement: Advances in Experimental Medicine and Biology, 1270
    DDC: 571.978
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Genetics. ; Molecular biology. ; Cancer Biology. ; Genetics and Genomics. ; Molecular Biology.
    Description / Table of Contents: 1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
    Abstract: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
    Type of Medium: Online Resource
    Pages: XVII, 167 p. 72 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030756994
    DDC: 571.978
    Language: English
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Diseases. ; Immunology. ; Bioinformatics. ; Cancer Biology. ; Diseases. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Obesity induced chronic low-level inflammation and cancers -- Chapter 2. Adipose tissue produced estrogen as risk factor for cancers -- Chapter 3. Insulin and Insulin-like growth factor-1 associated cancers.-Chapter 4. Adipokines play important role in cell proliferation and antiproliferation -- Chapter 5. mTOR and AMP-activated protein kinase in obesity and cancer -- Chapter 6. Immune response and oxidative stress in obesity induced cancer -- Chapter 7. Role of gene polymorphism in obesity and cancer -- Chapter 8. Therapeutic role of green tea in obesity and cancer -- Chapter 9. Effect of dietary phytochemicals in obesity and cancer -- Chapter 10. Resveratrol as anti-obesity and anticancer agent -- Chapter 11. EGCG as anti-obesity and anticancer agent -- Chapter 12. miRNAs as therapeutic target in obesity and cancer -- Chapter 13. In silico updates on lead identification for obesity and cancer -- Chapter 14. In vivo models for obesity and obesity related carcinogenesis -- Chapter 15. Estrogen signaling based current and potential therapies against obesity and related diseases -- Chapter 16. Autophagy at the crossroad of obesity mediated cancer progression.
    Abstract: This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry. .
    Type of Medium: Online Resource
    Pages: IX, 361 p. 38 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618468
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Biomedical engineering. ; Biochemical markers. ; Nanomedicine. ; Cancers. ; Biomedical Engineering and Bioengineering. ; Biomarkers. ; Cancer Nanotechnology.
    Description / Table of Contents: Chapter 1. Cancer of the Skin:Type and Etiology -- Chapter 2. Therapeutic intervention in skin cancer: Future prospects -- Chapter 3. Melanin Based Classification of Skin Types and Their Susceptibility to UV-induced Cancer -- Chapter 4. The Epidemiology of Skin Cancer Worldwide -- Chapter 5. UV-R induced Vitamin D synthesis and skin cancer -- Chapter 6. The role of microbiome in the induction, diagnosis and therapy of skin cancer -- Chapter 7. Skin Cancer: Molecular Biomarker for Diagnosis, Prognosis, Prevention and Targeted Therapy -- Chapter 8. Therapeutics intervention of skin cancer in the OMICS era -- Chapter 9. Artificial intelligence in Skin Cancer: Diagnosis and Therapy -- Chapter 10. Biomedical engineering in cancer diagnosis and therapy -- Chapter 11. Skin cancer treatment with Emphasis on Nanotechnology -- Chapter 12. Non-long coding RNA and role in skin cancer diagnosis and therapy -- Chapter 13. Potential of long non-coding RNAs in the diagnosis and therapy of melanoma skin cancer.-.
    Abstract: This book highlights the molecular and cellular mechanisms involved in the initiation and progression of skin cancer. It also explains the role of the environment in skin cancer development and explores the potential of microbiome in the diagnosis, prevention and treatment of skin cancer. The book also presents potential biomarkers for early detection of skin cancer and discusses recent advances in skin cancer prevention and treatment using photodynamic therapy. Lastly, it summarizes the applications of biomedical engineering, non-coding and nanotechnology in the diagnosis and therapeutics in skin cancer. It is a valuable resource for investigators in the field of skin cancer, including pathologists, medical and surgical oncologists, and dermatologists.
    Type of Medium: Online Resource
    Pages: VIII, 250 p. 27 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811603648
    DDC: 571.978
    Language: English
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    Keywords: Cancer. ; Genetics. ; Medical genetics. ; Cancers. ; Genetics and Genomics. ; Medical Genetics. ; Cancer Biology.
    Description / Table of Contents: Chapter 1. Polymorphisms and Mutation: What is difference? -- Chapter 2. Single nucleotide polymorphisms and pharmacogenomics -- Chapter 3. Impact of MicroRNA Polymorphisms on Breast Cancer Susceptibility -- Chapter 4. From inflammation to cancer: Role of genetic polymorphisms of Inflammatory Pathway Molecules in Gastric Cancer -- Chapter 5. Colorectal Cancer and genetic polymorphism in key regulatory low penetrance genes -- Chapter 6. Role of Genetic Polymorphisms in Breast Cancer -- Chapter 7. Genetic Polymorphisms of Essential Immune Pathogenic Response Genes and Risk of Cervical Cancer -- Chapter 8. Thyroid Cancer and genetic polymorphism -- Chapter 9. SNPs of TLRs and Bladder Cancer -- Chapter 10. Role of genetic polymorphisms in Lung Cancer.
    Abstract: This book discusses the role of genetic polymorphism in susceptibility to cancers. The book explores the understanding of differences between the genetic polymorphisms and mutations.It reviews the mechanisms underlying the effect of polymorphism in genes encoding proteins that play an essential role in metabolism, signal transduction, cell cycle, and DNA repair mechanisms. Further, it investigates various techniques that are used for analyzing the genetic polymorphisms. The book contains many chapters which summarize the importance of genetic information obtained from polymorphism-based pharmaco-genetic tests to predict better drug response and life-threatening adverse reactions to chemotherapeutic agents, help in understanding of the impact of SNPs on gene function, and gives overview of the different SNP databases for examination. This book, therefore, serves as an essential guidebook for independent researchers as well as institutions working in this specialised field.
    Type of Medium: Online Resource
    Pages: XXI, 339 p. 48 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813366992
    DDC: 571.978
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Biology. ; Cancer Treatment. ; Biotechnology. ; Molecular biology. ; Physiology. ; Cancer Biology. ; Biological Sciences. ; Cancer Therapy. ; Biotechnology. ; Molecular Biology. ; Physiology.
    Description / Table of Contents: Chapter 1. Introduction to Dietary Research and Cancer -- Chapter 2. Healthy Dietary Patterns and Cancer -- Chapter 3. Frequently Asked Diet and Nutrition Related Questions by Cancer Survivors -- Chapter 4. Dietary Recommendations of Worldwide Cancer Related Organizations -- Chapter 5. Outcome of ‘Diet and Cancer’ Related Clinical Trials -- 6. Diet and Cancer Epigenetics: A Step Towards Developing Cancer Epigenetic Diet -- 7. Role of Dietary Ingredients on Expression of Oncogenic and Tumor Suppressor miRNA -- 8. Can Diet Influence Metastasis? -- 9. Impact of Dietary Interventions on Cancer Stem Cells -- 10. Interaction of Dietary Metabolites with Anti-cancer Drug Targets -- 11. Revisiting the Anticancer Drug-Food Interactions -- 12. Functional Foods, Nutraceuticals, and Dietary Supplements in Cancer Prevention -- 13. Do Antioxidants Really Help Cancer Patients? The Puzzle of Benefits and Perils -- 14. Market of Dietary Supplements: Analysis of Health Benefits and Risk in Cancer -- 15. Cancer and Fasting: Can Fasting/Calorie Restriction (CR) or Fasting Mimicking Diet (FMD) Helps Fight Cancer? Molecular Basis of Fasting Response -- 16. Do Fasting, CR, and FMD Improves the Chemotherapy Response, Reduce Off Target Toxicities and Enhance Antitumor Immunity? Illusion or Clinical Reality? -- 17. Future Prospectus of Dietary Interventions in the Integrated Management of Cancer.
    Abstract: This book reviews all important aspects of dietary research associated with cancer with the aim of shedding new light on these conditions through combined understanding of traditional and new paradigms. The book is divided into 17 chapters, the first portion reinterprets healthy diets for cancer based on up-to-date evidence from a network science perspective, examining the dietary patterns, outcome of diet related clinical trials, emerging framework of molecular mechanisms and interactions of dietary interventions and their applications in personalized diet, ground realities of benefits and regulatory frame work for functional foods, nutraceuticals and supplements in cancer prevention and upcoming future prospectus in diet-cancer research.. The later part of the book discusses recent advances in understanding of the elaborative discourse on cancer and fasting, covering, for example, calorie restriction and fasting mimicking diet. Finally, different Dietary research and approaches are considered in the context of novel intervention for cancer research. Dietary Research in Cancer will be of interest for all researchers, nutritionists, students and clinicians in the field.
    Type of Medium: Online Resource
    Pages: XX, 197 p. 57 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811660504
    DDC: 571.978
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Cancer. ; Cell death. ; Cancer Biology. ; Cell Death.
    Description / Table of Contents: Preface -- Introduction -- The intersection of anoikis resistance and fatty acid metabolism in cancer -- Anoikis resistance in melanoma -- Anoikis mediated by stress-activated MAPK signaling pathways -- Metabolic Regulation of Anoikis -- Metabolic Reprogramming contributes to Anoikis resistance in Cancer Cells -- Role of the nuclear receptors in anoikis -- The roles of anoikis in cervical cancer -- Shc and the control of small GTPase dynamics in cellular anchorage -- Anoikis and the Human Gut Epithelium in Health and Disease -- Epithelial cell extrusion: the prelude to anoikis -- Microtubule modifications and mitochondria: role in anoikis.
    Abstract: This book provides a useful resource for graduate-level cancer cell biology courses. Since the first report, in 1994, of “anoikis”—the apoptosis that occurs when cells lack appropriate contact with the extracellular matrix—over 2,100 papers have been published on this subject. This book is the first comprehensive, in-depth and up-to-date compendium on anoikis. Chapters are authored by some of the leading researchers in the field. This book provides both mechanistic and translational information regarding anoikis, in a convenient format. Mechanistically, the following topics will be addressed in detail: The role of MAP kinase signaling The role of Shc proteins as cellular anchorage sensors The role of cellular metabolism, and fatty acid metabolism in particular, and how they are affected by oncogenic transformation How epithelial cell extrusion – the prelude to anoikis—is regulated in normal and cancer cells The convergence of TGF-b and androgen receptor signaling in the regulation of anoikis This book also discusses the specialized functions and dysregulation of anoikis in the following cancer settings: Colon cancer Melanoma Cervical cancer The book serves to update i nvestigators actively working on problems in the anoikis field, in either experimental or translational settings. For investigators encountering novel biological phenomena that might relate to anoikis, it serve as an entry point to the literature that does not require an extensive background in cell adhesion signaling or apoptosis mechanisms. .
    Type of Medium: Online Resource
    Pages: VIII, 202 p. 6 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030738563
    DDC: 571.978
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Human physiology. ; Immunology. ; Cancer Biology. ; Medical Microbiology. ; Biomedical Research. ; Human Physiology. ; Immunology.
    Description / Table of Contents: Chapter 1: The Microbiome And The Hallmarks Of Cancer -- Chapter 2: Microbiome In Human GI Cancers -- Chapter 3: The Gut Microbiome And Colorectal Cancer -- Chapter 4: Salmonella Infection In Human Cancers -- Chapter 5: Biomarkers Of Esophageal Cancers And Precancerous Lesions -- Chapter 6: Epithelial And Immune Cell Responses To Helicobacter Pylori That Shape The Gastric Tumor Microenvironment -- Chapter 7: Microbiome And Liver Cancer -- Chapter 8: THE MICROBIOME AND UROLOGIC CANCERS -- Chapter 9: Role Of Infections And Tissue Inflammation In The Pathology Of The Fallopian Tube And High-Grade Serous Ovarian Cancer -- Chapter 10: Commensal Microbes And Their Metabolites: Influence On Host Pathways In Health And Disease -- Chapter 11: Dietary And Microbiome In Cancer Prevention -- Chapter 12: Autophagy And Cancer-Current Biology And Drug Development -- Chapter 13: Mitochondrial Regulation Of Inflammation In Cancer -- Chapter 14: Modern Germ-Free Study Designs And Emerging Static Housing Technology In A Growing ‘Human Microbiome’ Market -- Chapter 15: Machine Learning In Identification Of Disease-Associated Microbiota -- Chapter 16: Mediation Analysis Of Microbiome Data And Detection Of Causality In Microbiome Studies.
    Abstract: This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
    Type of Medium: Online Resource
    Pages: XII, 509 p. 31 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030679514
    Series Statement: Physiology in Health and Disease,
    DDC: 571.978
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Conservation biology. ; Ecology . ; Human geography. ; Environmental sciences. ; Physics. ; Geographical Information System. ; Conservation Biology. ; Human Geography. ; Environmental Physics.
    Description / Table of Contents: From the Contents: Geographic Settings -- Spatial Locations of Nepal (Geopolitics) -- Culture, Religion, and Natural Resources -- Population Growth, Migration and Residential Mobility (Literature review and field verifications) -- Demographic Theory and Population Growth -- Fertility, Mortality, and Demographic Transition -- Human-environment relationships -- General Theory of Development and Migration -- Political Ecology of Land Encroachment -- Concepts and Determinants of Migration.
    Abstract: This monograph examines contemporary environmental challenges facing Nepal, this landlocked country’s representativeness in the wider South Asian context is both distinct and generalizable. In large part, this is because of its extremes of physiographical structure- plains, hill ranges, mountainous massifs - and wide range of altitudinal terrains, which represent and replicate South Asian and East Asian continental conditions differing as markedly as humid tropical lowlands, sub-tropical hill ranges and temperate to sub-arctic mountainous environments. Associated forest regimes, in which deforestation and reforestation patterns have evolved in recent times, and differing densities of settlement and cleared agricultural landscapes in each of these altitudinal zones, add to the environmental diversity of Nepal. Associated fauna and exotic species are in various states of endangerment especially Bengal tigers, one horned rhinos, wild elephants, crocodile, musk deer, and peasants, to name a few- so that their forested and mountainous habitats as ‘Wild Life Reserves’ also deserve our attention, and are featured in this monograph’s remit.
    Type of Medium: Online Resource
    Pages: XXXI, 764 p. 211 illus., 169 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030501686
    Series Statement: Advances in Asian Human-Environmental Research,
    DDC: 910.285
    Language: English
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Geography. ; Cultural property. ; Archaeology. ; Geographical Information System. ; Regional Geography. ; Archaeology and Heritage.
    Description / Table of Contents: Landscape archaeology: role of remote sensing and GIS -- Landscape morphology and spatial patterning of archaeological signatures when viewed from above -- The science and technology of remote sensing in context of archaeology -- GIS: an array of exceptional tools for archaeology -- RS and GIS for preservation, conservation and management.
    Abstract: This book is an introduction to a new branch of archaeology that scrutinises landscapes to find evidence of past human activity. Such evidence can be hard to detect at ground-level, but may be visible in remote sensing (RS) imagery from aerial platforms and satellites. Drawing on examples from around the world as well as from her own research work on archaeological sites in India (including Nalanda, Agra, Srirangapatna, Talakadu, and Mahabalipuram), the author presents a systematic process for integrating this information with historical spatial records such as old maps, paintings, and field surveys using Geographic Information Systems (GIS) to gain new insights into our past. Further, the book highlights several instances where these insights are actionable -- they have been used to identify, understand, conserve, and protect the fragile remnants of our past. This book will be of particular interest not only to researchers in archaeology, history, art history, and allied fields, but to governmental and non-governmental professionals working in cultural heritage protection and conservation.
    Type of Medium: Online Resource
    Pages: XXIII, 168 p. 86 illus., 81 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811574665
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Agriculture. ; Sustainability. ; Geographical Information System. ; Agriculture. ; Sustainability.
    Description / Table of Contents: Chapter 1. Introduction to Agro-geoinformatics: Theory and Practices -- Chapter 2: Remote sensing for agriculture -- Chapter 3. GIS fundamentals for agriculture -- Chapter 4. Agro-geoinformatics data sources and sourcing -- Chapter 5. Standards and interoperability -- Chapter 6. Image processing methods in agricultural observation systems -- Chapter 7. Data Fusion in Agricultural Information Systems -- Chapter 8. Big Data and its Applications in Agro-Geoinformatics -- Chapter 9. Land Parcel Identification -- Chapter 10. Crop Pattern and Status Monitoring -- Chapter 11. Crop Growth Modeling and Yield Forecasting -- Chapter 12. Spatial and Temporal Monitoring System for Agriculture -- Chapter 13. Spatial Data Usage in Turkish Agriculture -- Chapter 14. Geospatial Land Use and Land Cover Data for Improving Agricultural Area Sampling Frames -- Chapter 15. Mapping and Monitoring of Soil Moisture, Evapotranspiration and Agricultural Drought -- Chapter 16. Flood Monitoring and Crop Damage Assessment -- Chapter 17. Remote sensing-based mapping of plastic-mulched landcover -- Chapter 18. Design and Implementation of Geospatial Data Services for Agriculture. .
    Abstract: This volume collects and presents the fundamentals, tools, and processes of utilizing geospatial information technologies to process remotely sensed data for use in agricultural monitoring and management. The issues related to handling digital agro-geoinformation, such as collecting (including field visits and remote sensing), processing, storing, archiving, preservation, retrieving, transmitting, accessing, visualization, analyzing, synthesizing, presenting, and disseminating agro-geoinformation have never before been systematically documented in one volume. The book is edited by International Conference on Agro-Geoinformatics organizers Dr. Liping Di (George Mason University), who coined the term “Agro-Geoinformatics” in 2012, and Dr. Berk Üstündağ (Istanbul Technical University) and are uniquely positioned to curate and edit this foundational text. The book is composed of eighteen chapters that can each stand alone but also build on each other to give the reader a comprehensive understanding of agro-geoinformatics and what the tools and processes that compose the field can accomplish. Topics covered include land parcel identification, image processing in agricultural observation systems, databasing and managing agricultural data, crop status monitoring, moisture and evapotranspiration assessment, flood damage monitoring, agricultural decision support systems and more. .
    Type of Medium: Online Resource
    Pages: VI, 418 p. 152 illus., 101 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030663872
    Series Statement: Springer Remote Sensing/Photogrammetry,
    DDC: 910.285
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Telecommunication. ; Oceanography. ; Signal processing. ; Aerospace engineering. ; Astronautics. ; Geographical Information System. ; Communications Engineering, Networks. ; Ocean Sciences. ; Signal, Speech and Image Processing . ; Aerospace Technology and Astronautics.
    Description / Table of Contents: Introduction -- GNSS Signal -- Multipath Propagation -- Modeling and Simulation of GNSS Multipath Signals -- GNSS-R Receiver -- Data Processing for GNSS Reflectometry -- Wind Speed and Direction Retrieval -- Sea Surface Altimetry and Wave Height Estimation -- Sea Ice Detection -- Tsunami Detection and Parameter Estimation -- Snow Depth and Snow Water Equivalent Estimation -- Soil Moisture Retrieval.
    Abstract: This is the first authored English book completely focused on global navigation satellite system reflectometry (GNSS-R). It consists of two main parts: the fundamental theory; and major applications, which include ocean altimetry, sea surface wind speed retrieval, snow depth measurement, soil moisture measurement, tsunami detection and sea ice detection. Striking a healthy balance between theory and practice, and featuring in-depth studies and extensive experimental results, the book introduces beginners to the fundamentals, while preparing experienced researchers to pursue advanced investigations and applications in GNSS-R. .
    Type of Medium: Online Resource
    Pages: XI, 369 p. 257 illus., 244 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811604119
    Series Statement: Navigation: Science and Technology, 9
    DDC: 910.285
    Language: English
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Geographic information systems. ; Image processing Digital techniques. ; Computer vision. ; Geography. ; Geographical Information System. ; Computer Imaging, Vision, Pattern Recognition and Graphics. ; Geography.
    Description / Table of Contents: Foreword -- Preface -- Part I The Theory of a New GC Pattern -- Research background -- Relevant Research -- The New GC Pattern -- GeoComputation Language -- Part II The Practice of the New GC Pattern -- Implementation of G language -- Dual evaluation system of Territorial and Spatial planning -- Part III The Dual-evaluation geocomputation model -- Individual Evaluation -- Integrated Evaluation -- Optional Evaluations -- Comparative Analysis -- Map Analysis -- Appendix Layer Style of Thematic Map.
    Abstract: This book introduces Document As System (DAS), a new GeoComputation pattern, which is also a new GIS application pattern. It uses the GeoComputation language (G language) to describe and execute complex spatial analysis model in the MS Word environment, which solves the bottleneck problem of GIS application, makes GIS become a popular tool for spatial data analysis from the spatial data visualization tool, and plays an important role in the wide application of GIS technology. This book systematically introduces the theory related to the new GeoComputation pattern and the application example in the “dual-evaluation” of territorial and spatial planning, which can be used as a learning and reference manual for GIS related professionals and business personnel engaged in the “dual-evaluation” of territorial and spatial planning.
    Type of Medium: Online Resource
    Pages: XIX, 277 p. 155 illus., 82 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813364325
    DDC: 910.285
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    Keywords: Geographic information systems. ; Latin America History. ; Human geography. ; Cultural geography. ; Economic geography. ; Geographical Information System. ; Latin American History. ; Human Geography. ; Social and Cultural Geography. ; Economic Geography.
    Description / Table of Contents: Introduction -- Chapter 1. The first territorial incorporation of the southern lands and seas in modern cartography -- Chapter 2. The cartographic construction of a South Atlantic region: geopolitical and economic interests -- Chapter 3. Southern Patagonia, Tierra del Fuego, the South Atlantic Ocean and the Antarctic lands within global strategies -- Chapter 4. Conclusions -- Sources and Bibliography.
    Abstract: This volume describes the construction of the territorial identity of the southern end of South America and analyzes the cartographic territorialization of Patagonia, Tierra del Fuego and the “Terra Australis” continent. Different spatial representations and territorial nature coexisted in this process as a result of the spatial interpretation and value modes as well as the projects and strategies of various actors. The book discusses the formal and symbolic incorporation to the Spanish dominion and its inclusion in the imperial design built over a new image of the world. Examining Jesuit cartography it considers both the indigenous territoriality and the dynamics of relations between natural and social components in the continental hinterland. The process of cartographic differentiation for this southern Atlantic region is analyzed in the framework of early Antarctic exploration and competing use of navigation routes and maritime resources. The book emphasizes the role geopolitical and economic interests play in these developments. The formation of territorialities of various origins has particular contents and logic, which are built upon imaginary subordination to political and economic interests. Cartographic language in the 19th century, associated with political and commercial motivations and the (British) imperial ideology, stimulated the territorial expansion. The book argues why in the late 1800's this was an important factor in the integration process of the southern indigenous territories and the national territoriality.
    Type of Medium: Online Resource
    Pages: VIII, 180 p. 66 illus., 61 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030658793
    Series Statement: The Latin American Studies Book Series,
    DDC: 910.285
    Language: English
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    Cham :Springer International Publishing :
    Keywords: Geographic information systems. ; Public health. ; Medical informatics. ; Environmental geography. ; Geographical Information System. ; Public Health. ; Health Informatics. ; Integrated Geography. ; Integrated Geography.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: GeoComputation and Spatial Data Operation -- Chapter 3: E-Research & GeoComputation in Public Health -- Chapter 4: E-Research & GeoComputation in Public Health -- Chapter 5: GeoComputation & Disease exploration -- Chapter 6: GeoComputation and Disease Ecology -- Chapter 7: GeoComputation and Decision Making -- Chapter 8: GeoComputation and Spatial Modelling -- Chapter 9: GeoComputation and Public Participation in Disease Control.
    Abstract: GeoComputation and Public Health is fundamentally a multi-disciplinary book, which presents an overview and case studies to exemplify numerous methods and solicitations in addressing vectors borne diseases (e.g, Visceral leishmaniasis, Malaria, Filaria). This book includes a practical coverage of the use of spatial analysis techniques in vector-borne disease using open source software solutions. Environmental factors (relief characters, climatology, ecology, vegetation, water bodies etc.) and socio-economic issues (housing type & pattern, education level, economic status, income level, domestics’ animals, census data, etc) are investigated at micro -level and large scale in addressing the various vector-borne disease. This book will also generate a framework for interdisciplinary discussion, latest innovations, and discoveries on public health. The first section of the book highlights the basic and principal aspects of advanced computational practices. Other sections of the book contain geo-simulation, agent-based modeling, spatio-temporal analysis, geospatial data mining, various geocomputational applications, accuracy and uncertainty of geospatial models, applications in environmental, ecological, and biological modeling and analysis in public health research. This book will be useful to the postgraduate students of geography, remote sensing, ecology, environmental sciences and research scholars, along with health professionals looking to solve grand challenges and management on public health. .
    Type of Medium: Online Resource
    Pages: XXVIII, 298 p. 114 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030711986
    Series Statement: Springer Geography,
    DDC: 910.285
    Language: English
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  • 87
    Keywords: Geographic information systems. ; Application software. ; Geographical Information System. ; Computer and Information Systems Applications.
    Description / Table of Contents: Introduction -- Part I: Data analytics and the COVID-19 pandemic -- Smart governance and COVID-19 control in Wuhan, China -- Using public-private data to understand compliance with mobility restrictions in Sierra Leone -- Development of a spatio-temporal analysis method to support the prevention of COVID-19 infection: Space-time Kernel density estimation using GPS location history data -- Part II: Big data and smart cities -- A review of spatial network insights and methods in the context of planning: Applications, challenges, and opportunities -- Transport infrastructure, Twitter and the politics of public participation -- Public perceptions and attitudes towards driverless technologies in the United States: A text mining of Twitter data -- Assessing the value of new big data sources for transportation planning: Benton Harbor, Michigan case study -- How various natural disasters impact urban human mobility patterns: A comparative analysis based on geotagged photos taken in Tokyo -- Revealing the spatial preferences embedded in online activities: A case study of Chengdu, China -- Part III: Data-driven research of activity patterns -- Application for locational intelligence and geospatial navigation (ALIGN): Smart navigation tool for generating routes that meet individual preferences -- Pedestrian behaviour characteristics based on an activity monitoring survey in a university campus square -- Developing a GIS-based tourist walkability index based on the AURIN walkability toolkit – Case study: Sydney CBD -- Sequential patterns of daily human activity extracted from person trip survey data -- Understanding the economic value of walkable cities -- (Big) data in urban design practice: Supporting high-level design tasks using a visualization of human movement data from smartphones -- Examining passenger vehicle miles traveled and carbon emissions in the Boston metropolitan area -- Part IV: Open data and spatial modeling -- Development of a household urban micro-simulation model (HUMS) using available open-data and urban policy evaluation -- An agent-based bushfire visualisation to support urban planning: A case study of the South Coast, NSW 2019-2020 -- Development of an agent-based model on the decision-making of dislocated people after disasters -- Evidence-based design justice: Synthesizing statistics and stories – to create future "Just" cities -- Part V: Geodesign and planning support systems (PSS) -- Geodesign between IGC and geodesignhub: Theory and practice -- The role of technology tools to support geodesign in resilience planning -- Planning support systems for long-term climate resilience: A critical review -- Part VI: Geospatial data analysis -- Aggregation of geospatial data on "street units": The smallest geographical unit of urban places -- Local betweenness centrality analysis of 30 European cities -- Model for estimation of building structure and built year using building façade images and attributes obtained from a real estate database -- A spatial analysis of crime incidence and security perception around a university campus -- Sightseeing support system with augmented reality and no language barriers -- GeoMinasCraft: A serious geogame for geographical visualization and exploration.
    Abstract: This book forms a selection of chapters submitted for the CUPUM (Computational Urban Planning and Urban Management) conference, held in the second week of June 2021 at Aalto University in Helsinki, Finland. Chapters were selected from a double-blind review process by the conference's scientific committee. The chapters in the book cover developments and applications with big data and urban analytics, collaborative urban planning, applications of geodesign and innovations, and planning support science.
    Type of Medium: Online Resource
    Pages: XII, 632 p. 223 illus., 181 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030760595
    Series Statement: The Urban Book Series,
    DDC: 910.285
    Language: English
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  • 88
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Molecular genetics. ; Proteins . ; Cancer Biology. ; Molecular Genetics. ; Protein Biochemistry.
    Description / Table of Contents: Chapter 1: Overview of histone modification -- Chapter 2: The histone H3 family and its deposition pathways -- Chapter 3: Histone H3K27M Mutation in Brain Tumors -- Chapter 4: Histone Mutations and Bone Cancers -- Chapter 5: Histone H3G34 mutation in brain and bone tumors -- Chapter 6: Epigenetic-targeted treatments for H3K27M-mutant midline gliomas -- Chapter 7: Histone lysine to methionine mutation as anti-cancer drug target.
    Abstract: This book focuses on histone mutations, especially those mutations closely related to cancer. Genetic mutations and epigenetic alterations contribute to the development of a variety of cancers: recent genetic studies have identified e.g. H3K27M and H3G34R/V mutation in over 75% of DIPG cases, H3.3K36M mutation in more than 90% of chondroblastoma cases, and H3G34W/L mutation in over 90% of giant cell tumors of bone. Given the high incidence and tumorigenesis effects of histone H3 mutations, they are also referred to as oncohistones. This book highlights the advances made in the area over the past 10 years, and offers a state-of-the-art summary of epigenetic alternation, gene expression, protein structure, drug discovery, immunotherapy, and mouse modeling of histone H3 mutations in various tumors. Chiefly intended to provide researchers and graduate students with an overall picture of these mutations, it will also be of interest to researchers in basic oncology, clinical oncology, and epigenetics, as well as academics and clinical oncology practitioners.
    Type of Medium: Online Resource
    Pages: VII, 96 p. 17 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581045
    Series Statement: Advances in Experimental Medicine and Biology, 1283
    DDC: 571.978
    Language: English
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  • 89
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Human physiology. ; Diseases. ; Oncology. ; Regenerative medicine. ; Cancer Biology. ; Human Physiology. ; Diseases. ; Oncology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Chapter 1. Isolation and characterization of extracellular vesicles: classical and modern approaches -- Chapter 2. Characterization and fine structure of exosomes -- Chapter 3. Extracellular vesicles mediate the embryonic-maternal paracrine communication -- Chapter 4. The interplay between oviduct-derived exosomes and cumulus-oocyte complexes -- Chapter 5. The interplay between exosomes and spermatozoa -- Chapter 6. Mesenchymal stem cell-derived exosomes and regenerative medicine -- Chapter 7. Therapeutic Potential of Mesenchymal Stem/Stromal Cell Derived-Exosomes -- Chapter 8. Exosomes in Neurodegenerative Disorders -- Chapter 9. Differential expression of exosomal microRNAs in neurodegenerative diseases -- Chapter 10. Urinary exosomes as a possible source of kidney disease biomarkers -- Chapter 11. Extracellular vesicles as potential therapeutic targets and biomarkers for liver disease -- Chapter 12. Implications of extracellular vesicles in blood protozoan parasitic diseases -- Chapter 13. Cancer cells-derived Exosomes and Metastasis -- Chapter 14. Extracellular vesicles and integrins: partners in cancer progression -- Chapter 15. Exosomes: the crucial element in the prostate cancer -- Chapter 16. Exosomal microRNAs: Potential Biomarkers for Cancer Diagnosis, Treatment Response, and Prognosis -- Chapter 17. Exosomes in drug delivery -- Chapter 18. Exosomes and Supported Lipid Layers as Advanced Naturally Derived Drug Delivery Systems.
    Abstract: This book reviews the role of exosomes and extracellular vesicles in both normal and pathological conditions. It first explains isolation methods for exosomes, and analyzes their fine structure and biological functions. Further, it highlights exosomes’ role as the key regulator in embryonic-maternal communication, and in the pathogenesis of various diseases, including cancer and urogenital, infectious, and neurodegenerative diseases. Moreover, it reviews the latest advances in using stem-cell-derived exosomes as a cell-free strategy in regenerative medicine, as well as the potential of exosomal microRNA as a promising non-invasive biomarker and targetable factor in cancer diagnosis and treatment. Lastly, it explores the use of natural and synthetic exosomes as nano-vehicles for efficient drug delivery.
    Type of Medium: Online Resource
    Pages: XII, 373 p. 34 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811565991
    DDC: 571.978
    Language: English
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  • 90
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Biomedical Research.
    Description / Table of Contents: 1. NMR-Based Metabolomics in Cancer Research -- 2. Capillary Electrophoresis–Mass Spectrometry for Cancer Metabolomics -- 3. Chemical Isotope Labeling LC-MS for Metabolomics -- 4. Single cell metabolomics by mass spectrometry imaging -- 5. Fatty Acid Metabolism and Cancer -- 6. Metabolomics of Gastric Cancer -- 7. HIF-1α metabolic pathways in human cancer -- 8. Regulation of glycolysis in head and neck cancer -- 9. Metabolomics of oral/head and neck cancer -- 10. Ion chromatography with mass spectrometry for metabolomic analysis -- 11. Methods of lipidomic analysis: Extraction, derivatization, separation and identification of lipids -- 12. Functional metabolomics and chemoproteomics approaches reveal novel metabolic targets for anti-cancer therapy -- 13. Metabolomics of glioma -- 14. Microbial metabolomics: From methods to translational applications -- 15. Advances in the study of N6-methyladenine in eukaryotes -- 16. NMR Based Metabolomics -- 17. Quantitative analysis of oncometabolite 2-hydroxyglutarate -- 18. Tracer-based Cancer Metabolomic Analysis -- 19. Mass spectrometry-based shotgun lipidomics for cancer research -- 20. Comprehensive Two-dimensional Gas Chromatography Mass Spectrometry-based Metabolomics.
    Abstract: Cancer metabolomics is a rapidly evolving field that aims for a comprehensive dissection of the metabolic phenotypes and functional network of metabolites in human cancers. State of the art metabolomics tools have been developed and applied to studying cancer metabolism and developing metabolic targets for improved diagnosis, prognosis and therapeutic treatment of human cancers. Chapters are written by subject experts in the field of cancer metabolomics with cross-disciplinary contributions. Coverage includes advanced metabolomics technologies and methodologies, including chemical isotope labelling liquid chromatography - mass spectrometry, capillary ion chromatography - mass spectrometry, 2-D gas chromatography – mass spectrometry, capillary electrophoresis – mass spectrometry, nuclear magnetic resonance spectroscopy, shotgun lipidomics, tracer-based metabolomics, microbial metabolomics, mass spectrometry imaging for single cell metabolomics and functional metabolomics. In addition, the book highlights new discoveries in cancer metabolism such as hypoxia inducible factor pathway, isocitrate dehydrogenase 1 mutation and oncometabolites. Finally, contributors focus on the translational applications of metabolomics in human cancers such as glioma, head and neck cancer, and gastric cancer. This new volume will be a unique reference source for cancer researchers and promote applications of metabolomics in understanding cancer metabolism.
    Type of Medium: Online Resource
    Pages: XV, 312 p. 80 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030516529
    Series Statement: Advances in Experimental Medicine and Biology, 1280
    DDC: 571.978
    Language: English
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  • 91
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Immunology. ; Cancer Biology. ; Immunology.
    Description / Table of Contents: 1. The role of targeted therapy in multiple myeloma -- 2. Lenalidomide -- 3. Pomalidomide -- 4. Mechanisms driving resistance to proteasome inhibitors bortezomib, carfilzomib and ixazomib in multiple myeloma -- 5. Daratumumab -- 6. Elotuzumab -- 7. Histone deacetylase inhibitors -- 8. Bone targeted therapies -- 9. New targeted therapies for multiple myeloma under clinical investigation.
    Abstract: Multiple Myeloma remains an incurable malignancy. As the disease progresses, it invariably becomes resistant to treatment and almost all patients develop refractory disease. There are multiple different types of targeted therapies and many of them are used in combination at different stages of disease. Targeted therapies that are approved to be used include Proteasome Inhibitors, Immunomodulatory Drugs and Monoclonal Antibodies. Second and third generations of these drugs are developed to overcome resistance and they have unique mechanism of actions. Targeted therapies that are undergoing clinical trials include CAR-T cells, bi-specific antibodies, vaccines, ubiquitin ligase inhibitors and BCL-2 inhibitors. This book will help to develop an understanding of targeted therapies in Multiple Myeloma. Its goal is to provide a unique review of the mechanism of action and resistance of the many targeted therapies in Multiple Myeloma by leaders of the field. The book will be useful for students in medical science, clinicians, health professionals, scientists, pharmaceutical professionals, drug developers, and policy makers. This book will provide an insightful knowledge of the biology of Multiple Myeloma, the mechanism of action and resistance of targeted therapies, application of biomarkers and genomics and possible strategies in overcoming resistance and future development.
    Type of Medium: Online Resource
    Pages: XVII, 154 p. 5 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030734404
    Series Statement: Resistance to Targeted Anti-Cancer Therapeutics, 22
    DDC: 571.978
    Language: English
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  • 92
    Keywords: Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Description / Table of Contents: Notch signaling in prevention ant therapy: fighting cancer with a two-sided sword -- Transcription factor RBPJ as a molecular switch in regulating the Notch response -- Unraveling of Hidden Secrets: The tumour suppressor Lethal (2) giant discs (Lgd)/CC2D1, Notch Signaling and Cancer -- Notch and endometrial cancer -- Notch and Esophageal Squamous Cell Carcinoma -- Notch signaling and liver cancer -- Notch inHead and Neck Cancer -- Notch Signaling and Human Papillomavirus-Associated Oral Tumorigenesis -- The impact of Notch signalingfor carcinogenesis and progression of non-melanoma skin cancer: lessons learned fromcancer stem cells, tumor angiogenesis, and beyond -- Notch Signaling in Thyroid Cancer -- The Relevance of Notch Signaling in Cancer Progression -- Notch Signaling and the Breast Cancer Microenvironment -- Notch pathway: a journey from notching phenotypes to cancer immunotherapy -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more. Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
    Type of Medium: Online Resource
    Pages: XVII, 228 p. 28 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030550318
    Series Statement: Advances in Experimental Medicine and Biology, 1287
    DDC: 571.978
    Language: English
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  • 93
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Regenerative medicine. ; Medicine Research. ; Biology Research. ; Microtechnology. ; Microelectromechanical systems. ; Cancer Biology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Research. ; Microsystems and MEMS.
    Description / Table of Contents: Chapter 1. Strategies to improve oral delivery of natural anticancer molecules -- Chapter 2. Nanoparticles catalyzing enzymatic reactions: recent developments and future prospects -- Chapter 3. Biogenic silver nanoparticles: A potent therapeutic agent -- Chapter 4. Translational studies of nanofibers-based scaffold for skin and bone tissue regeneration -- Chapter 5. Functional Dendritic Coatings for Biomedical Implants -- Chapter 6. Application of nanotherapeutics for combating human protozoan parasitic infections.
    Abstract: This book illustrates the significance of nanotechnology in the delivery of anticancer and antimicrobial drugs, biomimetic technologies, tissue engineering, sensing, diagnostics, and artificial enzymes. It first briefly discusses the use of nanotechnology for the delivery of anticancer medications, and the concept and applications of catalytically active nanomaterial-based artificial enzymes for sensing and diagnostic applications. It then explores the use of silver nanoparticle-based novel antimicrobials, and comprehensively reviews the role of nanomaterials in developing biomedical implants and tissue engineering applications. Lastly, it offers a detailed description of nanotherapeutics for combating human protozoan parasitic infections. Cutting across the disciplines, this book serves as a guide for researchers and scientists in biotechnology, medical science and material science.
    Type of Medium: Online Resource
    Pages: XIV, 240 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811599200
    DDC: 571.978
    Language: English
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  • 94
    Keywords: Cancer. ; Tumor markers. ; Medical screening. ; Materials. ; Detectors. ; Cancer Biology. ; Tumour Biomarkers. ; Cancer Screening. ; Sensors and biosensors.
    Description / Table of Contents: Chapter 1. An Introduction to Cancer Biomarkers -- Chapter 2. Cervical Cancer -- Chapter 3. Potential Biomarkers for Early Diagnosis of Cervical Cancer -- Chapter 4. Methods for Screening of Cervical Cancer: State of Art -- Chapter 5. Electrochemical DNA Biosensors for Cervical Cancers -- Chapter 6. Optical DNA based Sensors for Cervical Cancers -- Chapter 7. Other Biosensors for Cervical Cancer Detection.
    Abstract: This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.
    Type of Medium: Online Resource
    Pages: IX, 115 p. 18 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811625862
    DDC: 571.978
    Language: English
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  • 95
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Cytology. ; Cancer Microenvironment. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: 1. The Tumour Microenvironment and Circulating Tumour Cells: A partnership driving metastasis and glycan-based opportunities for cancer control -- 2. Dormancy in the Tumor Microenvironment -- 3. Tumor-associated tertiary lymphoid structures: A cancer biomarker and a target for next-generation immunotherapy -- 4. Studying the tumor microenvironment in zebrafish -- 5. Pre-metastatic niche formation by neutrophils in different organs -- 6. Tumor cell invasion and the tumor microenvironment: Special focus on brain tumors -- 7. The dog as a model to study the tumor microenvironment -- 8. EFFEROCYTOSIS AND THE STORY OF “FIND ME’’, ‘’EAT ME” AND “DON’T EAT ME” SIGNALING IN THE TUMOR MICRO ENVIRONMENT -- 9. Color-coded imaging of the tumor micro-environment (TME) in human patient-derived orthotopic xenograft (PDOX) mouse models -- 10. Mitochondria and the tumor microenvironment in blood cancer -- 11. Telocytes in the tumor microenvironment -- 12. Modeling the roles of astrocytes in the metastatic tumor cell microenvironment -- 13. Roles of fibroblasts in microenvironment formation associated with radiation-induced cancer -- 14. Tumor microenvironment-associated pericyte populations may impact therapeutic response in thyroid cancer -- 15. The adrenergic nerve network in cancer -- 16. Current treatment modalities targeting tumor microenvironment in castration-resistant prostate cancer -- 17.Brain metastases and tumor microenvironment -- 18. MIGRATION STIMULATING FACTOR (MSF). ITS ROLE IN THE TUMOUR -- MICROENVIRONMENT -- 19. Mechanical Signaling in the Mammary Microenvironment - from Homeostasis to Cancer -- 20. Osteopontin Signaling in Shaping Tumor Microenvironment Conducive to Malignant Progression -- 21. Progesterone receptor signaling in the breast tumor microenvironment -- 22. Progranulin/GP88, a complex and multi-faceted player of tumor growth by direct action and via the tumor microenvironmen -- 23. Sex-based differences in the tumor microenvironmet. .
    Abstract: This volume discusses novel concepts in cancer biology, focusing on different factors that affect the tumor microenvironment. Topics covered include sex-based differences in the tumor microenironment, dormancy in the tumor microenvironment, the influence of obesity on the tumor microenvironment, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Novel Concepts covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 548 p. 79 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030731199
    Series Statement: Advances in Experimental Medicine and Biology, 1329
    DDC: 571.978
    Language: English
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  • 96
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Cytology. ; Proteins . ; Internal medicine. ; Cancer Microenvironment. ; Cancer Biology. ; Cell Biology. ; Protein Biochemistry. ; Internal Medicine.
    Description / Table of Contents: CCL2 in the tumor microenvironment -- CXCL3 signaling in the tumor microenvironment -- CXCL8 Signaling in the Tumor Microenvironment -- CXCL11 signaling in the tumor microenvironment -- CXCL12 signaling in the tumor microenvironment -- CXCL13 signaling in the tumor microenvironment -- CCL24 signaling in the tumor microenvironment -- CCL25 signaling in the tumor microenvironment -- CCL27 signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how they affect cancer immunity and tumorigenesis. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Chemokines – Part Bupdates us on what we know about various aspects of the tumor microenvironment, as well as apprises us on future directions in the field. This book is essential reading for advanced cell biology and cancer biology students as well as scientists seeking an update on recent developments and research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: IX, 139 p. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030626587
    Series Statement: Advances in Experimental Medicine and Biology, 1302
    DDC: 571.978
    Language: English
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  • 97
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Biomedical Research.
    Description / Table of Contents: 1. Defining breast cancer -- 2: Breast Cancer Recurrence and Survival -- 3: Synopsis of the Treatment of Breast Cancer -- 4: The Present Treatment of Hereditary Breast Cancer -- 5: Basis for the Epigenetic Treatment of Triple Negative Breast Cancer -- 6: A New Treatment Strategy foe BRCA1 Related Breast Cancer -- 7: Present Options in the Prevention of Breast Cancer -- 8: The Physiological Basis of Breast Cancer Prevention -- 9: The Present and Future of Screening in Breast Cancer Prevention -- 10: A Vision of the Future.
    Abstract: The objective of this book is to provide a critical analysis of the present prevention strategies for breast cancer, emphasizing the cost benefits and quality of life of the patient. Rooted in the present knowledge of breast cancer biology and prevention and treatment options, the book will describe the future tools that could be available to oncologists and how these new approaches may change the landscape of recurrence and survival of the disease. Special emphasis will be given to the prevention strategies counterposing the present limitations and conflicting prevention guidelines for both hereditary and preventive non-hereditary breast cancer, and propose how the implementation of new strategies based on the present knowledge could save millions of lives and be more cost efficient. The book will present a critical status of the treatment and prevention of breast cancer and detail how a quantum leap could be achieved in the field by applying present basic research knowledge to clinical application.
    Type of Medium: Online Resource
    Pages: XI, 192 p. 41 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030728151
    DDC: 571.978
    Language: English
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  • 98
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Clinical biochemistry. ; Cancer Biology. ; Biomedical Research. ; Medical Biochemistry.
    Description / Table of Contents: Part I. Introduction -- Chapter 1. Translational Research in Surgical Oncology: Introduction and My Own Experience as a Surgeon-Scientist -- Part II. Breast Cancer Biology and Cell Signaling Pathways -- Chapter 2. Phospholipase Signaling in Breast Cancer -- Chapter 3. HER2 Signaling in Breast Cancer -- Chapter 4. Ras Signaling in Breast Cancer -- Chapter 5. Epigenetic Regulation in Breast Cancer -- Chapter 6. Role of tRNAs in Breast Cancer Regulation -- Chapter 7. Fusion Genes in Breast Cancer -- Chapter 8. DNA Damage Repair Inhibitor for Breast Cancer Treatment -- Part III. Cancer Stem Cell and Tumor Heterogeneity in Breast Cancer -- Chapter 9. Breast Cancer Metastasis -- Chapter 10. Single Cell Genomics for Tumor Heterogeneity -- Chapter 11. Advances in Tumor Sampling and Sequencing in Breast Cancer and their Application in Precision Diagnostics and Therapeutics -- Chapter 12. Cancer Stem Cell in Immune Microenvironment -- Chapter 13. Theranostics for Breast Cancer Stem Cells -- Chapter 14. Patient-Derived Xenograft Models in Breast Cancer Research -- Part IV Biomarkers for Precision Medicine in Breast Cancer Patients -- Chapter 15. Proteomic Interrogation in Cancer Biomarker -- Chapter 16. Next-Generation Sequencing-Based Biomarkers in Breast Cancer -- Chapter 17. Liquid Biopsy in Breast Cancer: Circulating Tumor Cells and Circulating Tumor DNA -- Chapter 18. Current Biomarkers for Precision Medicine in Breast Cancer -- Chapter 19. The Potential Predictors in Chemotherapy Sensitivity -- Chapter 20. Hormone Resistance -- Part V. Managing High Risk Women -- Chapter 21. High-Risk Population Based on BC Risk Factors -- Chapter 22. Breast Cancer-Related Low Penetrance Genes -- Chapter 23. Rare Coding Variants Associated with Breast Cancer -- Chapter 24. Multigene Panel Testing for Hereditary Cancer and Genetic Counseling -- Chapter 25. BRCA and Breast Cancer-Related High-Penetrance Genes -- Part VI. Next Generation Clinical Research -- Chapter 26. Clinical Databases for Breast Cancer Research -- Chapter 27. Care for Breast Cancer Survivors -- Chapter 28. Considerations in Oncoplastic Surgery -- Chapter 29. Diet Before and After Breast Cancer -- Chapter 30. Current Trends in and Indications for Endoscopy-Assisted Breast Surgery for Breast Cancer -- Chapter 31. Minimal Invasive and Individualizing Management of the Axillary Nodes -- Chapter 32. Malignant Phyllodes of Breast -- Chapter 33. Next-Generation Clinical Trials and Research with Successful Collaborations -- Part VII. Epilogue -- Chapter 34. Transformation of the Patient and Society: A Patient Survivors’ Group and Breast Cancer Awareness Campaign.
    Abstract: This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment. It introduces ideas and materials derived from the clinic that have been brought to "the bench" for basic research, as well as findings that have been applied back to "the bedside". Detailed attention is devoted to breast cancer biology and cell signaling pathways and to cancer stem cell and tumor heterogeneity in breast cancer. Various patient-derived research models are discussed, and a further focus is the role of biomarkers in precision medicine for breast cancer patients. Next-generation clinical research receives detailed attention, addressing the increasingly important role of big data in breast cancer research and a wide range of other emerging developments. An entire section is also devoted to the management of women with high-risk breast cancer. Translational Research in Breast Cancer will help clinicians and scientists to optimize their collaboration in order to achieve the common goal of conquering breast cancer.
    Type of Medium: Online Resource
    Pages: IX, 630 p. 122 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813296206
    Series Statement: Advances in Experimental Medicine and Biology, 1187
    DDC: 571.978
    Language: English
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  • 99
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Metabolism. ; Cancer Treatment. ; Cancer Metabolism. ; Cancer Therapy. ; Cancer Biology.
    Description / Table of Contents: Part I. Basic Metabolism of Cancer Cells -- Glucose Metabolism in Cancer the Warburg effect and Beyond -- Glutamine Metabolism in Cancer -- The Heterogeneity of Lipid Metabolism in Cancer -- Part II. Heterogeneity of Cancer Metabolism -- The Multifaceted Glioblastoma: from Genomic Alterations to Metabolic Adaptions -- The Intricate Metabolism of Pancreatic Cancers -- The heterogeneity of breast cancer metabolism for therapy -- Non-Hodgkin Lymphoma Metabolism -- The Heterogeneity Metabolism of Renal Cell Carcinomas -- The Heterogeneity Metabolism of Liver Cancer -- Different Tumor Microenvironments Lead to Different Metabolic Phenotypes -- The Intratumoral Heterogeneity of Cancer Metabolism -- Cancer Stem Cells Metabolism -- Metabolism of Immune cells in the Tumor Microenvironment -- Part III. Relationship between Cancer Cells and Cancer-Associated Fibroblasts -- Metabolic Relationship between Cancer-Associated Fibroblasts and Cancer Cells -- Targeting Metabolic Cross Talk between Cancer Cells and Cancer-Associated Fibroblasts -- Part IV. The metabolic interplay between cancer and other diseases -- Diabetes and Cancer: the Epidemiological and Metabolic Associations -- Bridging the Metabolic Parallels between Neurological Diseases and Cancer -- Metabolic Intersection of Cancer and Cardiovascular Diseases: Opportunities for Cancer Therapy -- Index.
    Abstract: This open access volume will introduce recent discoveries in the field of cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, etc. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students. .
    Type of Medium: Online Resource
    Pages: XXIII, 271 p. 55 illus., 54 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030657680
    Series Statement: Advances in Experimental Medicine and Biology, 1311
    DDC: 571.978
    Language: English
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  • 100
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Tumors Immunological aspects. ; Cytology. ; Internal medicine. ; Cancer Microenvironment. ; Tumour Immunology. ; Cancer Biology. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: Interleukin-6 function and targeting in prostate cancer -- IL-7 signaling in the tumor microenvironment -- IL-10 Signaling in the Tumor Microenvironment of Epithelial Ovarian Cancer -- Targeted delivery of IL-12 adjuvants immunotherapy by oncolytic viruses -- IL-22 signaling in the tumor microenvironment -- IL-23 and the Tumor Microenvironment -- Interleukin (IL)-24: Reconfiguring the tumor microenvironment for eliciting antitumor response -- Interleukin-31, a potent pruritus-inducing cytokine and its role in inflammatory disease and in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of interleukins in the tumor microenvironment. Each chapter focuses on the various ways to target the tumor microenvironment by intervention in the interleukin biology, including IL-6, IL-7, IL-10, IL-12, IL-22, IL-23, and IL-24 signaling. Taken alongside its companion volumes, Tumor Microenvironment: The Role of Interleukins – Part Bupdates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XII, 134 p. 23 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030556174
    Series Statement: Advances in Experimental Medicine and Biology, 1290
    DDC: 571.978
    Language: English
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