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  • 1
    Online Resource
    Online Resource
    Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Molecular genetics. ; Gastroenterology. ; Oncology. ; Nanotechnology. ; Cancer Biology. ; Molecular Genetics. ; Gastroenterology. ; Oncology. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Potential Role of Biomarkers, Biosensors, Technologies and Computational Methods in Early Detection of Gastrointestinal Cancer -- Chapter 2. Biomarkers as the Promising Tools for Early Detection of Gastrointestinal Cancer -- Chapter 3. Development and Evaluation of Biomarkers for Early Detection of Cancer -- Chapter 4. Prognostic Molecular Markers for Gastrointestitinal cancer -- Chapter 5. Metabolic Markers for Early Detection of Gastrointestinal Cancer -- Chapter 6. Current Status of MicroRNA-based Biomarkers for Gastric Cancer -- Chapter 7. Genetic Susceptibility Markers of Gastrointestinal Cancer -- Chapter 8. Approaches For Early Detection Of Gastrointestinal Cancer -- Chapter 9. Biosensors and its Applications for Early Detection of Gastrointestitinal Cancer -- Chapter 10. Application of Nanotechnology in Early Detection of Gastrointestinal Cancer -- Chapter 11. Genetic Marker Identification for the Detection of Early-Onset Gastrointestitinal Cancer Through Genome Wide Association Studies -- Chapter 12. Big Data Analytics to Discover Diagnostics and Therapeutics for Gastrointestitinal Cancer -- Chapter 13. System Biology Approach for Early Prognosis of Gastrointestinal Cancer.
    Abstract: This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer. The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic biology devices, and 'omics' technologies for the early diagnosis of gastrointestinal cancer. In addition it examines the potential of genome-wide association studies, big data analytics, computation biology, systems biology, and nanotechnology for early diagnostics and therapeutics for gastrointestinal cancer, with a focus on personalized cancer treatment. The book is a valuable source for researchers and clinicians engaged in detection and diagnosis of gastrointestinal cancers.
    Type of Medium: Online Resource
    Pages: XXIII, 231 p. 38 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811544316
    Series Statement: Diagnostics and Therapeutic Advances in GI Malignancies,
    URL: https://doi.org/10.1007/978-981-15-4431-6
    DOI: 10.1007/978-981-15-4431-6
    DDC: 571.978
    Language: English
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  • 2
    Online Resource
    Online Resource
    Agricultural Drought in Slovakia: An Impact Assessment : NDVI and Satellite Based Data (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geographic information systems. ; Agriculture. ; Climatology. ; Environment. ; Geography. ; Ecology . ; Geographical Information System. ; Agriculture. ; Climate Sciences. ; Environmental Sciences. ; Regional Geography. ; Ecology.
    Description / Table of Contents: 1. Introduction/motivation -- 2. State of the art -- 3. Material and methods -- 4. Results -- 5. Conclusions -- References.
    Abstract: This book gives an insight into the evaluation of drought in Slovakia and provides an assessment of Normalized Difference Vegetation Index (NDVI) as a method suitable for an evaluation of drought in agricultural land. Dry seasons in the time series from 1960 to 2014 were determined according to the monthly Palmer Drought Severity Index (PDSI). The field research was carried out on 12 sites including western Slovakia, Prešov, Trnava and Nitra regions. Data collected from satellite imagery, climate data analyses and drought indices was analysed to determine the value of NDVI as an evaluation tool.
    Type of Medium: Online Resource
    Pages: IX, 90 p. 75 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030420611
    Series Statement: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-42061-1
    DOI: 10.1007/978-3-030-42061-1
    DDC: 910.285
    Language: English
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  • 3
    Online Resource
    Online Resource
    Autophagy in tumor and tumor microenvironment (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Immunology. ; Medical microbiology. ; Molecular genetics. ; Stem cells. ; Cell death. ; Cancer Biology. ; Immunology. ; Medical Microbiology. ; Molecular Genetics. ; Stem Cell Biology. ; Cell Death.
    Description / Table of Contents: Chapter 1. Role of xenobiotic in autophagy inflection in cell death and carcinogenesis -- Chapter 2. Autophagy – An agonist and antagonist with an interlink of apoptosis in cancer -- Chapter 3. Cross-talk between DNA damage and autophagy and its implication in cancer therapy -- Chapter 4. miRNAs and its regulatory role on autophagy in tumor microenvironment -- Chapter 5. Exploring the metabolic implications of autophagy modulation in tumor microenvironment -- Chapter 6. Mitophagy and Reverse Warburg Effect: Metabolic Compartmentalization of Tumor Microenvironment -- Chapter 7. Mitochondrial Biogenesis, Mitophagy, and Mitophagic cell death in Cancer Regulation: A Comprehensive Review -- Chapter 8. Mechanical stress-induced autophagy: a key player in cancer metastasis -- Chapter 9. The Interplay of Autophagy and the Immune system in the Tumor Microenvironment -- Chapter 10. Relevance of autophagy in cancer stem cell and therapeutic -- Chapter 11. The Autophagy Conundrum in Cancer Development, Progression and Therapeutics -- Chapter 12. Targeting Autophagy in Cancer: Therapeutic implications -- Chapter 13. Mechanistic insights into Autophagosome-Lysosome Fusion in Cancer Therapeutics.
    Abstract: This book deals with the paradoxical role of autophagy in tumor suppression and tumor promotion in cancer cells. Autophagy plays opposing, context-dependent roles in tumors; accordingly, strategies based on inhibiting or stimulating autophagy could offer as potential cancer therapies. The book elucidates the physiological role of autophagy in modulating cancer metastasis, which is the primary cause of cancer-associated mortality. Further, it reviews its role in the differentiation, development, and activation of multiple immune cells, and its potential applications in tumor immunotherapy. In addition, it examines the effect of epigenetic modifications of autophagy-associated genes in regulating tumor growth and therapeutic response and summarizes autophagy’s role in the development of resistance to a variety of anti-cancer drugs in cancer cells. In closing, it assesses autophagy as a potential therapeutic target for cancer treatment. Given its scope, the book offers a valuable asset for all oncologists and researchers who wish to understand the potential role of autophagy in tumor biology.
    Type of Medium: Online Resource
    Pages: VII, 280 p. 38 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811569302
    URL: https://doi.org/10.1007/978-981-15-6930-2
    DOI: 10.1007/978-981-15-6930-2
    DDC: 571.978
    Language: English
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  • 4
    Online Resource
    Online Resource
    Phytochemicals Targeting Tumor Microenvironment in Gastrointestinal Cancers (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Oncology. ; Cancer Biology. ; Oncology.
    Description / Table of Contents: Role of specific phytochemicals against gastrointestinal malignancies -- Role of phytochemicals on growth and metastasis of GI cancer -- Cancer Stem Cells as Therapeutic Targets for Gastrointestinal cancers -- Phytochemicals plus checkpoint inhibitors in GI cancers -- Crucial role of curcumin on gut microbiota associated with GI cancers -- Cellular and Molecular mechanisms of garlic compounds in common GI cancers -- Combination of Phytochemicals with Nanotechnology for Targeting GI Cancer Therapy -- Emerging Roles of Phytochemicals in the Pathobiology and Management of Esophageal Cancer -- Gastric Cancer: Role of Phytochemicals and Tyrosine Kinase Inhibitors -- Therapeutic Efects Of Curcumin Against Colorectal Cancer -- Molecular Pathways Involved in the Pathogenesis of Pancreatic Cancer: Role of Phytochemicals in Targeting the Clinical Outcomes -- Role of Dietary Supplementation of Natural products in the Prevention and Treatment of Liver Diseases -- Emerging Roles of Phytochemicals in Hepatocellular Carcinoma -- Phytochemicals: Current Understandings of the Modern Therapeutic Approaches for Hepatocellular Carcinoma -- Index.
    Abstract: Gastrointestinal (GI) malignancies account for a large portion of cancers worldwide. Although incidence of esophageal, gastric, and colorectal cancers has decreased in recent years, pancreatic and liver cancer have increased. The mainstay of GI cancer therapy is chemoradiation and surgery. Despite significant medical advancements, diagnosis and therapy for GI cancers remain challenging due to tumor cell resistance to chemoradiotherapy. The tumor’s increased cell signalling due to excessive transcription factor activation and increased stellate cell activity leads to collagen deposition formation of a dense stroma around the tumor, which prevents drugs from reaching the malignant cells. This leads to tumor chemoresistance. To circumvent these difficulties, drug therapy targeting the tumor’s specific microenvironment and the additive anticancer effect of phytochemicals can allow for more effective treatment. This volume will be the first on the market on the topic of phytochemicals and their effect on the tumor microenvironment (TME). TME is an emerging area of research and the book will be a welcome introductory addition to the field.
    Type of Medium: Online Resource
    Pages: XI, 340 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030484057
    URL: https://doi.org/10.1007/978-3-030-48405-7
    DOI: 10.1007/978-3-030-48405-7
    DDC: 571.978
    Language: English
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  • 5
    Online Resource
    Online Resource
    Digital Cultural Heritage (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geographic information systems. ; Cultural property. ; Multimedia systems. ; Geographical Information System. ; Cultural Heritage. ; Multimedia Information Systems.
    Description / Table of Contents: Augmenting Network Analysis with Linked Data for Humanities Research -- A Memorial Design Pattern Catalogue for commemorative digital culture -- Annotation in Digital Humanities -- Establishment of a complex database for the study of cultural her-itage through the reading and analysis of the traditional architecture of Upper Kama -- Urban History Research and Discovery in the Age of Digital Repositories. A Report about Users and Requirements -- Digital Infrastructures for Digital Humanities in International Textbook Research.-Digital preservation of cultural heritage for small institutions -- Body As Echoes: Cyber Archiving of Buddhist Deities In the Cave Temples of China -- A Multivariate Use of Digital Cultural Heritage: Online Resources for Archaeology in the DBAS – MUSINT Websites -- Rebuilding the Past: 3D Reconstruction and BIM Analysis of a Neolithic House at La Draga -- 3D Modeling applications to terracotta figurines from Plakomenos, Greece -- Virtual Collection of Cuneiform Tablets as a Complex Multilevel System with Interdisciplinary Content -- The Potentials of the Digital Cultural Heritage: A Best practice Example of Presentation and Use. The Digital Representation of the Hans Gross Kriminalmuseum -- Planning for the End from the Start: an Argument for Digital Stewardship, Long-Term Thinking and Alternative Capture Approaches for Digital Content -- Semantic Data-Modelling and Long-term Interpretability of Cultural Heritage Data – Three Case Studies -- From classic (analogue) to digital forms of cultural heritage protection in Poland -- From classic (analogue) to digital forms of cultural heritage protection in Poland -- Libraries, Archives, and Museums Interwoven in the Digital South: From a Paucity of Resources to Data Richness for Understanding the South Asian Subcontinent -- Cultural Heritage digital data: future and ethics -- The Cartography Project: towards a relational form of documentation, the case of participatory art practices in museums and art galleries -- Digitization of old maps and possible on-line tools for their use.-efoto Hamburg: From Image Data to a Digitally Mediated Cultural Heritage Process -- 3D sketching of the fortified entrance of the Citadel of Aleppo from a few sightseeing photos.-The integrated survey of the Pergmum by Nicola Pisano in the cathedral of Pisa -- Virtual representation of archaeological stratigraphy. 3D modeling and interactive presentation of the late roman towers (Archaeological Museum , Milan) -- Opening up Research Data in Film Studies by Using the Structured Knowledge Base Wikidata -- Gamification in cultural heritage: A tangible user interface game for learning about local heritage -- Quasi–Mixed Reality in Digital Cultural Heritage. Combining 3D Reconstructions with Real Structures on Location – the Case of Ancient Phalasarna -- Digitization of Acoustic Heritage in a service of Protection, Research and Promotion of European Cultural Heritage.
    Abstract: This book provides an overview of various application spheres and supports further innovations needed in information management and in the processes of knowledge generation. The professions, organizations and scientific associations involved are unusually challenged by the complexity of the data situation. Cartography has always been the central field of application for georeferencing digital cultural heritage (DCH) objects. It is particularly important in enabling spatial relation analysis between any number of DCH objects or of their granular details. In addition to the pure geometric aspects, the cognitive relations that lead to knowledge representation and derivation of innovative use processes are also of increasing importance. Further, there is a societal demand for spatial reference and analytics (e.g. the extensive use of cognitive concepts of "map" and "atlas" for a variety of social topics in the media). There is a huge geometrical-logical-cognitive potential for complex, multimedia, digital-cultural-heritage databases and stakeholders expect handling, transmission and processing operations with guaranteed long-term availability for all other stakeholders. In the future, whole areas of digital multimedia databases will need to be processed to further our understanding of historical and cultural contexts. This is an important concern for the information society and presents significant challenges for cartography in all these domains. This book collects innovative technical and scientific work on the entire process of object digitization, including detail extraction, archiving and interoperability of multimedia DCH data.
    Type of Medium: Online Resource
    Pages: VII, 447 p. 192 illus., 148 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030152000
    URL: https://doi.org/10.1007/978-3-030-15200-0
    DOI: 10.1007/978-3-030-15200-0
    DDC: 910.285
    Language: English
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  • 6
    Online Resource
    Online Resource
    Microwave Remote Sensing Tools in Environmental Science (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geographic information systems. ; Telecommunication. ; Sustainability. ; Environmental management. ; Environment. ; Geographical Information System. ; Microwaves, RF Engineering and Optical Communications. ; Sustainability. ; Environmental Management. ; Environmental Sciences.
    Description / Table of Contents: 1 Basic Concepts of Microwave Radiometry -- 2 Remote Sensing Technologies and Data Processing Algorithms -- 3 Constructive Method of Vegetation Microwave Monitoring -- 4 Microwave Remote Sensing of Soil Moisture -- 5 Vegetation Screening Effect in the Remote Sensing Monitoring -- 6 Microwave Tools for the Diagnostics of Forest Fires -- 7. Space Methods and Monitoring Tools for the Investigation of Aquatic Systems. -- 8 Microwave Remote Sensing Monitoring and Global Climate Change Problems -- 9 Global Climate Monitoring with Microwave Measurements -- References -- Index.
    Abstract: This book gives new insight to the study of the global environmental changes using the ecoinformatics and microwave remote sensing tools together with the adaptive-evolutionary technology of geoinformation monitoring. The main advantage of this book consists in the accumulation of the interdisciplinary scientific knowledge for the parameterization of the global biogeochemical cycles and other environmental processes in the context of globalization and sustainable development. In this regard, the crucial global problems of the dynamics of the climate-nature-society system have been considered and the key problems of ensuring its sustainable development have been addressed. An analysis of the present trend in changing ecological systems has been discussed, including different types of forest ecosystems and ocean aquatories. The emphasis has been given to the accomplishment of the global geoinformation monitoring, which could provide a reliable control of the environmental processes development with reliable prognostic estimates of the consequences of human activities. A new approach to the numerical modelling of the climate-nature-society system has been presented and demonstrative results have been given about the modelling of the dynamics of this system‟s characteristics, in cases of realization of some scenarios of the anthropogenic impacts to the biogeochemical cycles, the land ecosystems and oceans. Methods and algorithms for the big data manipulation and processing in the remote sensing environmental monitoring systems have been described.
    Type of Medium: Online Resource
    Pages: XXIII, 468 p. 139 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030457679
    URL: https://doi.org/10.1007/978-3-030-45767-9
    DOI: 10.1007/978-3-030-45767-9
    DDC: 910.285
    Language: English
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  • 7
    Online Resource
    Online Resource
    Pharmacotherapeutic Botanicals for Cancer Chemoprevention (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Medical genetics. ; Pharmaceutical chemistry. ; Bioinformatics. ; Cancer Biology. ; Medical Genetics. ; Pharmaceutics. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Phytochemicals in Cancer Chemoprevention: A Brief Perspective -- Chapter 2. Phytochemicals in Modulating Signalling Cascades in Cancer Cells -- Chapter 3. Diverse cancer therapeutic interactions: complexities in cancer management -- Chapter 4. Natural Products as Chemosensitizers for Adjunct Therapy in Cancer Management -- Chapter 5. Dietary phytochemicals as epigenetic modulators in cancer prevention: Emerging research trends, gaps, and future perspectives -- Chapter 6. Modulation of Cancer Cell Metabolism and Microenvironment by Phytochemicals -- Chapter 7. Role of Nutrigenetics and Nutrigenomics in Cancer Chemoprevention -- Chapter 8. Nano-delivery carriers for Enhanced Bioavailability of Antitumor Phytochemicals -- Chapter 9. Biphasic Effects of Phytochemicals and their Relevance to Cancer Therapeutics -- Chapter 10. Potential Pharmacotherapeutic Phytochemicals from Zingiberaceae for Cancer Prevention -- Chapter 11. 3 Dimensional Cell Culture Techniques in Cancer Research -- Chapter 12. Animal Models Systems of Cancer for Preclinical Trials -- Chapter 13. Cancer Chemoprevention by Natural Plant Products and Their Derivatives: Clinical Trials.
    Abstract: The book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics. Over the last few decades there has been a paradigm shift from conventional cancer therapeutic approaches to alternative and complementary medicinal approaches especially using phytoconstituents from natural products. As such, the book provides an in-depth understanding of phytochemicals targeting diverse signaling pathways involved in cancer along with the evaluation of the cancer modulatory effects of phytochemicals. It also highlights the potential modulatory effect of single nucleotide polymorphisms (SNPs) on the cancer-associated cellular pathways and their interactions with the phytochemicals. Further, it analyzes the drug delivery methods, bioavailability of active components of botanicals, and toxicity of phytochemicals. Lastly, the book elucidates the 3D cell culture and animal models systems to analyze the beneficial effects of phytochemicals in cancer.
    Type of Medium: Online Resource
    Pages: XII, 337 p. 120 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811559990
    URL: https://doi.org/10.1007/978-981-15-5999-0
    DOI: 10.1007/978-981-15-5999-0
    DDC: 571.978
    Language: English
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  • 8
    Online Resource
    Online Resource
    Redox Regulation and Therapeutic Approaches in Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cancer. ; Metabolism. ; Cancer Treatment. ; Biochemistry. ; Oxidation-reduction reaction. ; Cancer Metabolism. ; Cancer Therapy. ; Redox Biology.
    Description / Table of Contents: 1. ROS, redox regulation and signaling in cancer cells -- 2. ROS and redox regulation/signaling and metabolism in cancer stem cells -- 3. . ROS/Redox regulation with dietary phytochemicals and role in anticancer activity -- 4. ROS/Redox signaling and apoptosis/necroptosis/autophagy in cancer -- 5. Cancer Metastasis, ROS/redox signaling and PCD resistance/redox metabolism -- 6. Immune system, redox signaling and cancer immunity -- 7. P53, ROS- redox regulation signaling, metabolic reprogramming and autophagy in cancer -- 8. Cell cycle, DNA damage-repair systems and impact of redox regulation in cancer -- 9. ROS, redox regulation and anticancer therapy -- 10. Perspectives in ROS/redox regulation cancer therapy.
    Abstract: This book aims to provide an association of the major redox-sensitive pathways and networks involved in cancer. The initial chapter of the book discusses basic information about oxidative stress, its generation, and regulation (redox regulation or redox homeostasis) via cell signaling in normal and cancer cells. The book also explores antioxidants and metabolic events in cancer cells compared to normal cells. It further covers the application of nanoparticles in redox regulation in cancer cells. The role of redox regulation in cancer therapy, its influence, and its involvement in programmed cell death (PCD), metastasis, immune system, p53, and cell cycle/DNA damage repair pathways have been discussed in separate chapters. It further reviews the importance of dietary phytochemicals in redox regulation in normal and cancer pathophysiology. Towards the end, the book focuses on the role of redox balance, especially in ROS-dependent cellular processes in cancer stem cells.
    Type of Medium: Online Resource
    Pages: XI, 431 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819973422
    URL: https://doi.org/10.1007/978-981-99-7342-2
    DOI: 10.1007/978-981-99-7342-2
    DDC: 571.978
    Language: English
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  • 9
    Online Resource
    Online Resource
    Hepatobiliary Cancers: An Interdisciplinary Approach (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Tumors Immunological aspects. ; Immunotherapy. ; Cancer Genetic aspects. ; Stem cells. ; Cancer Biology. ; Cancer Therapy. ; Tumour Immunology. ; Immunotherapy. ; Cancer Genetics and Genomics. ; Cancer Stem Cells.
    Description / Table of Contents: Interdisciplinary Approach in Hepatobiliary Cancers -- Liver Cancer: Interdisciplinary Approach -- The Immune System in Liver Cancer: From Beginning to Progression -- The Tumor Microenvironment in Hepatocellular Carcinoma -- Metabolic Alterations of Hepatocellular Cancer Stem Cells -- Τhe Role of Senescence in NASH-related HCC -- Regulators of Genetic Risk for the Progression of Non-alcoholic Fatty Liver Disease to Hepatocellular Carcinoma: Reconstruction of Transcriptional Network and Signature-Based Metabolic Profiling -- Tumor Microenvironment and Immunotherapy in Advanced Biliary Tract Cancers -- Fibrosis and Immunotherapy in Hepatocellular Carcinoma -- Liver Cancer and the Curative Potential of Nanomedicine -- Locoregional Therapies for Hepatocellular Carcinoma -- Drug Resistance in Hepatocellular Carcinoma -- Liver Stereotactic Body Radiotherapy.
    Abstract: Hepatobiliary cancers, including hepatocellular carcinoma and biliary tract cancers, have high rate of mortality and low survival rate. The third volume of the “Interdisciplinary Cancer Research” series, entitled “Hepatobiliary Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of hepatobiliary cancers and therapeutic modalities and presents the most updated and peer-reviewed chapters on hepatobiliary cancers. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on hepatobiliary cancers.
    Type of Medium: Online Resource
    Pages: XI, 365 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031445286
    Series Statement: Interdisciplinary Cancer Research, 3
    URL: https://doi.org/10.1007/978-3-031-44528-6
    DOI: 10.1007/978-3-031-44528-6
    DDC: 571.978
    Language: English
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  • 10
    Online Resource
    Online Resource
    Gastrointestinal Cancers: An Interdisciplinary Approach (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Oncology. ; Immunotherapy. ; Tumors Immunological aspects. ; Nanomedicine. ; Cancer Biology. ; Cancer Therapy. ; Oncology. ; Immunotherapy. ; Tumour Immunology. ; Cancer Nanotechnology.
    Description / Table of Contents: Interdisciplinary Approach in Gastrointestinal Cancers -- Gastrointestinal Cancers: What Is the Real Board of Microenvironment and the Role of Microbiota-Immunity Axis -- Epithelial-Mesenchymal Transition in Gastrointestinal Cancer: From a Basic to a Clinical Approach -- Metabolomics of Gastrointestinal Cancers -- Deregulation of Immune System in Gastric Cancer Development, How Immune Nutrition Might Restore the Functions of Immune Cells -- Helicobacter pylori Virulence Factors, Pathogenicity, and Gastric Cancer -- Gastric Cancer and Helicobacter pylori -- Role of Neuromodulators in Regulation of the Tumor Microenvironment of Gastric and Colorectal Cancers -- The Role of Tumor Microenvironment in Colon Cancer -- Unraveling the Esophageal Cancer Tumor Microenvironment: Insights and Novel Immunotherapeutic Strategies -- The Interplay Between Immunity and Gut Microbiota in Colon Cancer -- Immunotherapy in Gastrointestinal Cancer Focusing on CAR-T Cell Therapy -- Development of Biocompatible Nanocarriers for the Treatment of Colorectal Cancer -- Challenges of Onco-therapeutics in Early Onset Colorectal Cancer -- Unintentional Weight Loss and Malnutrition After Esophageal Cancer and Treatment -- Current Clinical Landscape of Immunotherapeutic Approaches in Pancreatic Cancer Treatment. The Tumor Microenvironment in Pancreatic Cancer and Challenges to Immunotherapy. .
    Abstract: Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume. The fourth volume of the “Interdisciplinary Cancer Research” series, entitled “Gastrointestinal Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers.
    Type of Medium: Online Resource
    Pages: XI, 404 p. 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031483714
    Series Statement: Interdisciplinary Cancer Research, 4
    URL: https://doi.org/10.1007/978-3-031-48371-4
    DOI: 10.1007/978-3-031-48371-4
    DDC: 571.978
    Language: English
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