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  • Books  (2)
  • Biology Research.  (2)
  • Cham :Springer International Publishing :  (2)
  • Berlin : Akad.-Verl.
  • Berlin [u.a.] : Springer
  • De Gruyter
  • 571.878  (2)
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  • Books  (2)
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  • Cham :Springer International Publishing :  (2)
  • Berlin : Akad.-Verl.
  • Berlin [u.a.] : Springer
  • De Gruyter
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  • 1
    Online Resource
    Online Resource
    Senescence Back and Forth (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Aging. ; Medicine Research. ; Biology Research. ; Public health. ; Biotechnology. ; Psychiatry. ; Ageing. ; Biomedical Research. ; Public Health. ; Chemical Bioengineering. ; Psychiatry.
    Description / Table of Contents: Senescence opposed to longevity -- Genetics, the language of Proteomics -- Plants Uncover Senescence Animals Way Off Humans -- Rejuvenation stops Senescence -- Overlap of Senescence with Disease -- Mosaic Restricted to the Individuum -- Remaining Time until Death -- Laboratory Checkups -- eroprotectors.
    Abstract: This book is about lifelong ageing of humans. The basic biochemical and genetic mechanisms remain ill known, and differ among individuals. The book starts out to explore the plant and animal kingdoms to answer questions human ageing needs for understanding. First, we come to scrutinize time running out and what ‘normal’ means with impacts on the genome and on protein half- lives and function. Ageing goes beyond biochemical skid treated by geroprotector drugs, including biosimilars; albeit early diagnosis with standard medical laboratory assays, here addressed, sheds light with focus on basic research. Modern tools, including machine learning, and DNA technology, e.g. genomics, have already provided for unanticipated insights. The chapters then turn around senescence of the entire organism based on variable ageing of single organs embedded in neuronal networks . Psychological stress factors, dementia opposed to vigilance, and distinction of ageing from overt disease are contrasting in humans and are opposed in the book. Senescence, seen as a one way track may be reverted into rejuvenation, made possible by insights into immunosenescence and genomic approaches. Risk management in health insurance finds important clues in this book. The topics addressed between the book covers help to understand the trend to the ever- prolonging life expectancy beyond the centenarian age group; nursing care takers and pharmaceutical industry are invited to understand what’ is going on in senior people to make their geriatric population remain fit or become frail.
    Type of Medium: Online Resource
    Pages: XXIII, 132 p. 38 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031322761
    URL: https://doi.org/10.1007/978-3-031-32276-1
    DOI: 10.1007/978-3-031-32276-1
    DDC: 571.878
    Language: English
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  • 2
    Online Resource
    Online Resource
    Sleep and Clocks in Aging and Longevity (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Aging. ; Cytology. ; Circadian rhythms. ; Neurosciences. ; Medicine Research. ; Biology Research. ; Ageing. ; Cellular Circadian Rhythms. ; Neuroscience. ; Biomedical Research.
    Description / Table of Contents: Sleep and circadian clock : Novel players in health impacts and Aging -- Cells and circuits of the suprachiasmatic nucleus and the control of circadian behaviour and sleep -- Circadian roles in sleep -- Age-related decline in the central circadian clock -- Cellular clocks in senescent cells -- Optimum sleep for healthy aging.
    Abstract: This edited volume focuses on the interplay between sleep and circadian rhythms with health, aging and longevity. Sleep is absolutely important for human health and survival, as insufficient sleep is associated with a plethora of conditions, including the poor quality of life, onset of several diseases, and premature death. The sleep–wake cycle is an evolutionary conserved neurobiological phenomenon, and is a prominent manifestation of the biological clocks localised in the suprachiasmatic nucleus (SCN). Understanding bidirectional relationship between sleep and circadian rhythms is of utmost importance and urgency, especially in the context of modern lifestyle where sleep is often out of phase with the internal body clocks, social jetlag, artificial lights and so on. The 25 chapters by leading researchers and experts from 11 countries are arranged into seven sections: understanding sleep and clock interlink in health and longevity; sleep, aging and longevity; clock, aging and longevity; melatonin, sleep and clock; genetic regulation of sleep and clock; therapeutic interventions in sleep disorders and clock misalignment; and experimental models to study sleep and clocks in aging and longevity. This book is useful for advanced undergraduate and graduate students, and researchers, educators, and other biomedical professionals. .
    Type of Medium: Online Resource
    Pages: IX, 561 p. 125 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031224683
    Series Statement: Healthy Ageing and Longevity, 18
    URL: https://doi.org/10.1007/978-3-031-22468-3
    DOI: 10.1007/978-3-031-22468-3
    DDC: 571.878
    Language: English
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