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  • Books  (32)
  • Stem Cell Biology.  (17)
  • Biomedical Research.  (10)
  • Oncology.  (6)
  • Cham :Springer International Publishing :  (32)
  • Berlin [u.a.] : Springer
  • De Gruyter
  • RAND Corporation
  • 571.6  (32)
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  • Books  (32)
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  • 1
    Online Resource
    Online Resource
    Cell Biology and Translational Medicine, Volume 7 : Stem Cells and Therapy: Emerging Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Medical genetics. ; Biotechnology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Clinical Genetics. ; Chemical Bioengineering.
    Description / Table of Contents: Application of iPSC to modelling of respiratory diseases -- Gene editing in human pluripotent stem cells: recent advances for clinical therapies -- Vascular wall as source of stem cells able to differentiate into endothelial cells -- Physiological and therapeutic roles of neuropeptide Y on biological functions -- Rho signaling-directed YAP/TAZ regulation encourages 3D spheroid colony formation and boosts plasticity of Parthenogenetic Stem Cells -- Transamniotic Stem Cell Therapy -- Regenerative medicine: Injectable cell-based therapeutics and approved products -- Stem Cell Therapy for Hepatocellular Carcinoma: Future Perspectives -- Potential of tribological properties of metalnanomaterials in biomedical applications -- The impact of the low frequency of the electromagnetic field on human.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the seventh volume of a continuing series Chapter “Application of iPSC to Modelling of Respiratory Diseases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 153 p. 30 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378455
    Series Statement: Cell Biology and Translational Medicine, 1237
    URL: https://doi.org/10.1007/978-3-030-37845-5
    DOI: 10.1007/978-3-030-37845-5
    DDC: 571.6
    Language: English
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  • 2
    Online Resource
    Online Resource
    Cell Biology and Translational Medicine, Volume 9 : Stem Cell-Based Therapeutic Approaches in Disease (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Medical genetics. ; Biotechnology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Medical Genetics. ; Biotechnology.
    Description / Table of Contents: Data Analysis of Infection Rates Among Exposed Healthcare Workers Could Reveal Effective Prophylactics Against SARS-CoV-2 -- Immune Responses to SARS-CoV, MERS-CoV AND SARS-CoV-2 -- Normothermic Preservation of Liver – What does the Future Hold? -- Tissues from Post-Mortem Donors as Alternative Sources of Stem Cells for Regenerative Medicine -- New Pioneers of Optogenetics in Neuroscience -- A Current Overview of Scaffold-Based Bone Regeneration Strategies with Dental Stem Cells -- The Importance of Stem Cell Senescence in Regenerative Medicine -- Hematological Malignancies and Fertility -- Unraveling polymeric nanoparticles cell uptake pathways: two decades working to understand nanoparticles journey to improve gene therapy -- Cellular Dust as a Novel Hope for Regenerative Cancer Medicine.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the ninth volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 163 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030549176
    Series Statement: Cell Biology and Translational Medicine, 1288
    URL: https://doi.org/10.1007/978-3-030-54917-6
    DOI: 10.1007/978-3-030-54917-6
    DDC: 571.6
    Language: English
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  • 3
    Online Resource
    Online Resource
    Tight Junctions (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Neurosciences. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Cell Biology. ; Neuroscience. ; Biomedical Research. ; Pharmacology.
    Description / Table of Contents: A historical and evolutionary view of tight junctions -- Tricellular tight junctions -- Mechanosensitivity of tight junctions -- Intracellular traffic and non-canonical roles of ZO-2 protein -- Impact of claudin-2 and occludin expression in inflammation disorders -- Tight junctions in the inflamed gut -- Intestinal barrier disruption by enteropathogenic Escherichia coli -- Tight junction barrier function regulation by microbiota -- Claudin-7 participation in cell-substrate adhesion, cell migration, salt balance in the renal collecting duct and gut cell renewal and differentiation -- Regulation of the alveolar epithelial barrier by claudin-5 -- Regulation of the blood-retinal barrier by occludin phosphorylation, norrin and sonic hedgehog signaling -- Transmigration of metastatic cells through the blood-brain barrier -- Endocytosis of tight junction proteins -- Regulated degradation of claudins. .
    Abstract: This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells. The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice. The chapters also explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia). This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume is particularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.
    Type of Medium: Online Resource
    Pages: XII, 334 p. 47 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030972042
    URL: https://doi.org/10.1007/978-3-030-97204-2
    DOI: 10.1007/978-3-030-97204-2
    DDC: 571.6
    Language: English
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  • 4
    Online Resource
    Online Resource
    Proteostasis and Disease : From Basic Mechanisms to Clinics (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Neurosciences. ; Immunology. ; Medicine Research. ; Biology Research. ; Cancer. ; Cell Biology. ; Neuroscience. ; Immunology. ; Biomedical Research. ; Cancer Biology.
    Description / Table of Contents: Part I. Cancer -- Ubiquitin-Regulated Cell Proliferation and Cancer -- Ubiquitin, SUMO, and Nedd8 as Therapeutic Targets in Cancer -- The Proteasome System in Health and Disease -- Proteostasis Dysregulation in Pancreatic Cancer -- Divergent Modulation of Proteostasis in Prostate Cancer -- Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma -- Part II. Neurodegeneration -- Altered Proteostasis in Neurodegenerative Tauopathies -- The Ubiquitin System in Alzheimer’s Disease -- The Interplay Between Proteostasis Systems and Parkinson’s Disease -- Machado–Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides -- Part III. Infection, Inflammation and Developmental Disorders -- SUMO and Cytoplasmic RNA Viruses: From Enemies to Best Friends -- The Role of Proteostasis in the Regulation of Cardiac Intercellular Communication -- By the Tips of Your Cilia: Ciliogenesis in the Retina and the Ubiquitin-Proteasome System -- TRIM E3 Ubiquitin Ligases in Rare Genetic Disorders -- Part IV. Diet -- We Are What We Eat: Ubiquitin–Proteasome System (UPS) Modulation Through Dietary Products.
    Abstract: This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology. Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.
    Type of Medium: Online Resource
    Pages: XII, 348 p. 42 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030382667
    Series Statement: Advances in Experimental Medicine and Biology, 1233
    URL: https://doi.org/10.1007/978-3-030-38266-7
    DOI: 10.1007/978-3-030-38266-7
    DDC: 571.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cancer Biology and Advances in Treatment (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Cancer. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Cancer Biology.
    Description / Table of Contents: 1. The BRCA1 and BRCA2 genes in early onset breast cancer patients -- 2. Anti-cancer effect of Xao tam phan Paramignya trimera methanol root extract on human breast cancer cell line MCF-7 in 3D model -- 3. A novel nonsense mutation c.374C〉G in CYP21A2 gene of a Vietnamese patient with congenital adrenal hyperplasia -- 4. Variation of Mitochondrial DNA HV1 AND HV2 of the Vietnamese Population -- 5. Synthesis and Characterization of PLGA-PEG Thymoquinone Nanoparticles and its Cytotoxicity Effects in Tamoxifen-resistant Breast Cancer Cells -- 6. Adipose-derived mesenchymal stem cells promote growth and migration of lung adenocarcinoma cancer cells -- 7. Predictive potential of PD-L1, TYMS and DCC expressions in treatment outcome of colorectal carcinoma -- 8. Clinical trials with cytokine-induced killer cells and CAR-T cell transplantation for non-small cell lung cancer treatment -- 9. Isopanduratin A isolated from Boesenbergia pandurata reduces HepG2 hepatocellular carcinoma cell proliferation in both monolayer and three-dimensional cultures -- 10. Hopea Odorata extract can efficiently kill breast cancer cells and cancer stem like cells in three-dimensional culture more than in monolayer cell culture -- 11. Selective cytotoxicity of some plant extracts against hepatocellular carcinoma cells but not mesenchymal stem cells: A pilot screening.
    Abstract: This new series, based on a bi-annual conference and its topics, represents a major contribution to the emerging science of cancer research and regenerative medicine. Each volume brings together some of the most pre-eminent scientists working on cancer biology, cancer treatment, cancer diagnosis, cancer prevention and regenerative medicine to share information on currently ongoing work which will help shape future therapies. These volumes are invaluable resources not only for already active researchers or clinicians but also for those entering these fields, plus those in industry. Cancer Biology and Advances in Treatment is a proceedings volume which reflects papers presented at the 3rd bi-annual Innovations in Regenerative Medicine and Cancer Research conference; taken with its companion volume Tissue Engineering and Regenerative Medicine and Stem Cells: Biology and Engineering it provides a complete overview of the papers from that meeting of international experts. .
    Type of Medium: Online Resource
    Pages: XI, 174 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030572549
    Series Statement: Innovations in Cancer Research and Regenerative Medicine, 1292
    URL: https://doi.org/10.1007/978-3-030-57254-9
    DOI: 10.1007/978-3-030-57254-9
    DDC: 571.6
    Language: English
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  • 6
    Online Resource
    Online Resource
    Potency Assays for Advanced Stem Cell Therapy Medicinal Products (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Medical microbiology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Medical Microbiology.
    Description / Table of Contents: The Art of Cell Therapy -- Scope and Applicability of Autologous Cell Therapies -- Scale and Accessibility of Allogeneic Cell Therapies -- Acellular Stem Cell Products. Potency Assays: The Buggy Boo of Stem Cell Therapy -- Potency Assay Development: A Keystone for Clinical Use -- Quantifying Critical Quality Attributes -- Advanced Technologies for Potency Assay Measurement -- Potency Quality by Design: Tailoring for Specific Therapy -- Contract Research Organizations Expediting Therapeutic Availability -- Regulatory Authority Perspectives for Potency Release Criteria -- Illustrative Potency Assay Examples from Approved Therapies -- The Integrity of Potency Assays and Safe Intervention -- The Evolving Landscape of Potency Assays.
    Abstract: This volume of the Springer book series Advances in Experimental Medicine and Biology covers potency assays, one of the most complex yet fundamental evaluations that critically influence stem cell regenerative medicine. Developing potency assays for cell-based medicinal products comes with numerous challenges due to the highly specialised nature of the application and purpose. This book provides the reader with the knowledge necessary to understand issues governing the successful development of potency assays, highlighting an international outlook of how the various challenges raised are being managed. Stakeholders concerned with potency assay development range from patient and clinician to contract research organisations, small and medium enterprise, regulatory authorities and even politicians. The value of potency assays is poised to increase given the inevitable watershed as early-stage clinical trials addressing safety progress to trials testing efficacy. Contributors from clinical, academic, industrial and regulatory sectors establish a broad point of view for guidance and timely debate. Potency assays require extensive collaboration across disciplines and sectors, as well as compromise and the authors aim to constructively address the many key aspects involved. Potency assays provide a quantitative measure of the biological activity of advanced therapy medicinal products (ATMPs) and thus are required for their market authorization. As the pace of ATMP development accelerates, the need to develop specific, accurate, and robust potency assays for each product is also accelerating. The volume Potency Assays for Stem Cell Advanced Therapy Medicinal Products presents a broad outlook on the development, quality attributes, and implementation of potency assays for ATMPs. The first few chapters introduce a nuanced historical perspective on the science of potency assay development, describe specific quality attributes of an idealized potency assay, indicate pitfalls associated with developing such assays for ATMPs, and review guidance recommended by regulatory authorities on assay suitability for product approval. Subsequent chapters highlight efforts to develop potency assays for specific ATMPs, including skeletal stem cells, mesenchymal stromal cells, extracellular vesicles, CAR T-cells, and discuss emerging technologies/platforms for potency assay design. The volume concludes with a chapter reviewing potency assays used for the release of commercial ATMP products, which amalgamates information contained in previous chapters. Overall, the knowledge contributed from leading authorities in both academia and industry is an ideal resource for technicians, scientists, clinicians, process engineers, and regulators working with ATMPs. —Donald G. Phinney, PhD Professor, Department of Molecular Medicine, Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology .
    Type of Medium: Online Resource
    Pages: XIX, 214 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031300400
    Series Statement: Advances in Experimental Medicine and Biology, 1420
    URL: https://doi.org/10.1007/978-3-031-30040-0
    DOI: 10.1007/978-3-031-30040-0
    DDC: 571.6
    Language: English
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  • 7
    Online Resource
    Online Resource
    Macropinocytosis : Functions and Mechanisms (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Biophysics. ; Cell interaction. ; Biological transport. ; Cell membranes. ; Medicine Research. ; Biology Research. ; Cell Biology. ; Mechanobiological Cell Signaling. ; Membrane Trafficking. ; Biomedical Research.
    Description / Table of Contents: Part 1: Functions of Macropinocytosis -- Chapter 1: Functional Diversity of Macropinocytosis -- Chapter 2: Macropinocytosis and Cancer: From Tumor Stress to Signaling Pathways -- Chapter 3: The amoebal model for micropinocytosis -- Chapter 4: Extracellular ATP and macropinocytosis -- Chapter 5: Macropinocytosis and Cell Migration: Don't drink an drive -- Chapter 6: Macropinocytosis in phagocyte function and immunity -- Part 2: Signaling Mechanisms Driving Macropinocytosis -- Chapter 7: Roles of 3' Phosphoinositides in Macropinocytosis -- Chapter 8: Signaling pathways that regulate macropinocytosis in mammalian cells -- Chapter 9: Wnt, GSK3 and Macropinocytosis -- Chapter 10: Kras addiction promotes cancer cell adapation in harsh microenvironment through micropinocytosis -- Chapter 11: Kras-independent macropinocytosis in pancreatic cancer.
    Abstract: This book presents the functions and mechanisms of macropinocytosis, an actin-driven endocytic uptake process. Key points, including the evolutionary origins of macropinocytosis and major signaling pathways that regulate this uptake mechanism, are highlighted. A wide-array of functions of macropinocytosis are described, including cellular metabolism, cell death, cell migration and antigen presentation. Macropinocytosis has recently been recognized as a critical pathway in disease pathology and treatment. Therefore, a broad overview of macropinocytosis will benefit clinicians, as well as translational and basic research scientists. Moreover, as one of the main clathrin-independent endocytic routes, compiling all the critical information about macropinocytosis in one collection, this book will also be helpful to educators and their students.
    Type of Medium: Online Resource
    Pages: XI, 224 p. 28 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030940041
    Series Statement: Subcellular Biochemistry, 98
    URL: https://doi.org/10.1007/978-3-030-94004-1
    DOI: 10.1007/978-3-030-94004-1
    DDC: 571.6
    Language: English
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  • 8
    Online Resource
    Online Resource
    Organoid Technology for Disease Modelling and Personalized Treatment (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Stem cells. ; Regenerative medicine. ; Diseases Animal models. ; Medicine Research. ; Biology Research. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Disease Models. ; Translational Research.
    Description / Table of Contents: Chapter 1. The hope and the hype in organoid technology in regenerative medicine (Badrul Hisham Yahaya) -- Chapter 2. Pluripotent stem cell derived and adult-tissue-derived organoid (Tiago G. Fernandes) -- Chapter 3. Generation of human organoid for 3D stem cell culture Hans Clevers -- Chapter 4. Organogenesis in a dish: Organ developmental study using organoid technology (Kursad Tuksen) -- Chapter 5. Disease modelling using patient-derived organoid (Narisorn Kitiyanant) -- Chapter 6. Tumor organoid as a model to study cancer microenvironment (Ahmad Faried) -- Chapter 7. Gene-editing in organoid to improve understanding of human disease (Yinming Liang) -- Chapter 8. Organoid culture as a good model to study lung development (Mitsuru Morimoto) -- Chapter 9. Organoid as good model for respiratory diseases (Badrul Hisham Yahaya).-Chapter 10. In vitro 3D model on reproductive system (Ruttachuk Rungsiwiwut) -- Chapter 11. Modelling of neuronal organoid: The way forward and challenges (Juntang Lin) -- Chapter 12. Generation of cardiac organoid in early heart organogenesis (Tan Jun Jie) -- Chapter 13. Neural Crest-Derived Stem Cells in organoid development for neurodegenerative disease modelling (Darius Widera) -- Chapter 14. Organoid for drug discovery and personalized treatment (Toshio Takahashi) -- Chapter 15. Ethical concern on patient-derived organoid (Phuc Van Pham).
    Abstract: Organoid Technology for Disease Modelling and Personalised Treatment provides a comprehensive overview of current knowledge of the organoid as a human-organ-in-a-dish, a powerful new technology for studying fundamental aspects of human organ development and disease progression in the search for drugs for personalised treatment. This preclinical tool is extensively being utilised as a model for studying human diseases in a dish, which is critical for accurate predictive modelling in precision medicine. The chapters in this book introduces readers to the numerous applications of organoids in various fields of study, as well as ethical considerations associated with organoids. In stem cell biology and regenerative medicine, where chimaera research, biomaterials for tissue vascularisation, gene-editing technologies, and their use in clinical procedures especially issues related to ethical concern over the use of human organoids have gotten much attention. Organoid Technology for Disease Modelling and Personalised Treatment is an excellent resource for in-depth research on one of the most interesting and significant topics in stem cell and regenerative medicine. This book's chapter collection covers a fresh viewpoint on organoid technology that scholars will require reading.
    Type of Medium: Online Resource
    Pages: VI, 208 p. 2 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030930561
    Series Statement: Stem Cell Biology and Regenerative Medicine, 71
    URL: https://doi.org/10.1007/978-3-030-93056-1
    DOI: 10.1007/978-3-030-93056-1
    DDC: 571.6
    Language: English
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  • 9
    Online Resource
    Online Resource
    Oxygen Transport to Tissue XLIV (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Regenerative medicine. ; Medicine Research. ; Biology Research. ; Bioinformatics. ; Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Research. ; Bioinformatics.
    Description / Table of Contents: Brain Tissue Oxygen and BOLD fMRI Under Different Levels Of Neuronal Activity -- Cerebral Microcirculation and Oxygenation Modulation by Transcranial Alternating Current Stimulation in Awake and Anesthetized Mice -- The Effect of Hypercapnia on Cortical Metabolic Rate and Mitochondrial Redox Status -- Relationship Between Left-Right Dominancy of Prefrontal Cortex Activity and Heart Rate During Rest and Task Periods: An fNIRS Study -- Relationship Between Cognitive Function, Oral Conditions and Systemic Metabolic Function in the Elderly -- Pro-survival Phenotype of HIF-1α: Neuroprotection through Inflammatory Mechanisms -- Infradian Rhythms in Cerebrovascular Oxygenation and Blood Volume in Humans at Rest: A 5-year Study -- Mechanisms of Photostimulation of Brain’s Waste Disposal System: the Role of Singlet Oxygen -- Changes of Arterial and Venous Cerebral Blood Flow Correlation in Moderate-to-Severe Traumatic Brain Injury: A CT Perfusion Study -- Cerebral Net Water Uptake in Posttraumatic Cerebral Ischemia -- Brainstem Damage Underlies Changes in Hypoxic Ventilatory Response following Cardiac Arrest and Resuscitation in Rats -- Differences Between Good, Moderate and Poor Performers of a Verbal Fluency Task under Blue Light Exposure: An SPA-fNIRS Study -- Sex-specific and Dose-dependent Effects of Drag-Reducing Polymers on Microcirculation and Tissue Oxygenation in Rats after Traumatic Brain Injury -- Accuracy of Tissue Oxygen Saturation Measurements of a Textile-based NIRS Sensor -- Understanding the Role of Caveolae in Oxygen Buffering: The Effect of Membrane Curvature -- The Significance of Lipids for the Absorption and Release of Oxygen in Biological Organisms -- How Skin Color Depends on Tissue Oxygenation -- Tissue Concentration Analysis of Sulfur, Calcium and Oxygen in novel Skin Primo Nodes After Acupuncture -- Primo Vessels Inside Lymphatic Vessels are Absent in an ALS Mouse Model -- The Impact of Heterogeneous Cell Density in Hypoxic Tumors Treated with Radiotherapy -- A Critical Analysis of Possible Mechanisms for the Oxygen Effect in Radiation Therapy with FLASH -- Hyperhydration of Cancers: A Characteristic Biophysical Trait Strongly Increasing O2, CO2, Glucose and Lactate Diffusivities, and Improving Thermophysical Properties of Solid Malignancies -- No Difference in Muscle Basal Oxygenation in a Bedridden Population pre and Post Rehabilitation -- Relationship between Muscle Deoxygenation and Cardiac Output in Subjects without Attenuation of Deoxygenation Hemoglobin Concentration near the end of Ramp Cycling Exercise: A Longitudinal Study -- Image Reconstruction Using Deep Learning for Near-Infrared Optical Tomography: Generalization Assessment -- Neonatal Brain Temperature Monitoring Based on Broadband Near-Infrared Spectroscopy -- Time Domain Near-Infrared Optical Tomography Utilizing Full Temporal Data: A Simulation Study -- BIAN: A Multilayer Microfluidic-Based Tissue-Mimicking Phantom for Near-Infrared Imaging -- Do Vascular and Extracellular Measurements Consistently Reflect Intracellular pO2? Observation of Tissue Oxygenation Changes using Remote Photoplesysmography with a Smartphone -- Neurovascular, Metabolic, and Glymphatic Dynamics of the Brain Measured with fNIRS -- Imaging Cerebral Blood Vessels Using Near-Infrared Optical Tomography: A Simulation Study -- Reduced Cerebrovascular Oxygenation in Individuals with Post-Acute COVID-19 Syndrome (PACS) (“Long COVID”) -- Insufficient Oxygen Supplementation During Cardiopulmonary Resuscitation Leads to Unfavorable Biological Response While Hyperoxygenation Contributes to Metabolic Compensation -- Block of the Angiotensin Pathways Affects Flow-Volume Spirometry in Patients With SARS-CoV-2 Infection -- A Prospective Observational Pilot Study on the Effects of the Activity-based Stress Release Program on the Mental State and Autonomic Nervous System in Psychiatric patients. .
    Abstract: This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 49th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2022). Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.
    Type of Medium: Online Resource
    Pages: XIX, 240 p. 91 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031420030
    Series Statement: Advances in Experimental Medicine and Biology, 1438
    URL: https://doi.org/10.1007/978-3-031-42003-0
    DOI: 10.1007/978-3-031-42003-0
    DDC: 571.6
    Language: English
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  • 10
    Online Resource
    Online Resource
    Cell Biology and Translational Medicine, Volume 15 : Stem Cells in Tissue Differentiation, Regulation and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Stem cells. ; Medicine Research. ; Biology Research. ; Cell Biology. ; Stem Cell Biology. ; Translational Research.
    Description / Table of Contents: Molecular Mechanisms of SARS-CoV-2/COVID-19 Pathogenicity on the Central Nervous System: Bridging Experimental Probes to Clinical Evidence and Therapeutic Interventions -- The Probable Protective Effect of Photobiomodulation on the Inflammation of the Airway and Lung in COVID-19 Treatment: A Preclinical and Clinical Meta-Analysis -- Metabolomics Signatures of SARS-CoV-2 Infection -- Autophagic Mediators in Bone Marrow Niche Homeostasis -- Pluripotency Stemness and Cancer: More Questions than Answers -- In Vitro Culturing of Adult Stem Cells: The Importance of Serum and Atmospheric Oxygen -- Mouse Models of Asthma: Characteristics, Limitations and Future Perspectives on Clinical Translation -- From Cells to Organs: The Present and Future of Regenerative Medicine -- Tissue-Restricted Stem Cells as Starting Cell Source for Efficient Generation of Pluripotent Stem Cells: An Overview -- Molecular Mechanisms behind Persistent Presence of Parvovirus B19 in Human Dilated Myocardium.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s long-standing and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 15th volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 206 p. 31 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031023781
    Series Statement: Cell Biology and Translational Medicine, 1376
    URL: https://doi.org/10.1007/978-3-031-02378-1
    DOI: 10.1007/978-3-031-02378-1
    DDC: 571.6
    Language: English
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