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  • 1
    Online Resource
    Online Resource
    Essentials of Tissue and Cells Banking (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    URL: https://doi.org/10.1007/978-3-030-71621-9
    DOI: 10.1007/978-3-030-71621-9
    DDC: 610.72
    Language: English
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  • 2
    Online Resource
    Online Resource
    Coenzyme Q in Aging (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Biochemistry. ; Physiology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Biochemistry. ; Physiology.
    Description / Table of Contents: Preface -- Part 1 Basics on coenzyme Q -- Introduction. The current coenzyme Q science and knowledge -- Molecular structure, biosynthesis, and distribution of coenzyme Q -- Coenzyme Q function in mitochondria -- Extramitochondrial coenzyme Q10 in aging -- Regulation of the synthesis of Coenzyme Q10 -- Part 2 Coenzyme Q in aging studies -- Coenzyme Q and aging in C. elegans -- Coenzyme Q and aging in the fruit fly Drosophila melanogaster -- The aging process and coenzyme Q: clk-1 mouse models -- Reduced coenzyme Q10 decelerates senescence and age-related hearing loss in senescence-accelerated mice by activating mitochondrial functions -- Part 3 Age-related diseases and coenzyme Q -- Coenzyme Q, mtDNA and mitochondrial dysfunction during aging -- Coenzyme Q10 and metabolic syndrome -- Coenzyme Q and age-related neurodegenerative disorders: Parkinson and Alzheimer diseases -- Immunosenescence and CoQ10 -- Coenzyme Q10 in fertility and reproduction -- Part 4 Prolongevity effectors and Coenzyme Q -- Calorie restriction, longevity and coenzyme Q -- Age dependent changes of coenzyme Q levels and its induction in experimental systems -- Effects of coenzyme Q10 supplementation on elderly people -- Index.
    Abstract: This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ10 is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging. The book is organized in four sections. The first offers an overview of the function of CoQ10, highlighting the two main functions of CoQ10 in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. The second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ on longevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. The final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ10 levels by induction of synthesis or by supplementation. Coenzyme Q in Aging benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process.
    Type of Medium: Online Resource
    Pages: XII, 369 p. 50 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030456429
    URL: https://doi.org/10.1007/978-3-030-45642-9
    DOI: 10.1007/978-3-030-45642-9
    DDC: 610.72
    Language: English
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  • 3
    Online Resource
    Online Resource
    Molecular Mechanisms in Spermatogenesis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Reproductive health. ; Cytology. ; Biomedical Research. ; Reproductive Medicine. ; Cell Biology.
    Description / Table of Contents: Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases -- Ch 2: Sertoli cells: immunology and spermatogenesis -- Ch 3: Innate immunity and spermatogenesis -- Ch 4: Cell apoptosis and spermatogenesis -- Ch 5: Transcriptional regulation of spermatogenesis -- Ch 6: Sertoli cell cytoskeleton and spermatogenesis -- Ch 7: Leydig cell and spermatogenesis -- Ch 8: Cross-talk of cell junctions to support spermatogenesis -- Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis -- Ch 10: Regulation of the blood-testis barrier by basement membrane laminin-α2 chain -- Ch 11: Regulation of spermatogenesis by collagens -- Ch 12: Androgen regulation of spermatogenesis -- Ch 13: Use of molecular modeling to study spermatogenesis -- Ch 14: Acrosome biogenesis during spermatogenesis -- Ch 15: Stem cells and spermatogenesis -- Ch 16: Advances in our understanding of spermatogenesis in humans -- Ch 17: Leydig cell function in aging men -- Ch 18: Regulation of human spermatogenesis.
    Abstract: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
    Type of Medium: Online Resource
    Pages: X, 319 p. 44 illus., 40 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030777791
    Series Statement: Advances in Experimental Medicine and Biology, 1381
    URL: https://doi.org/10.1007/978-3-030-77779-1
    DOI: 10.1007/978-3-030-77779-1
    DDC: 610.72
    Language: English
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  • 4
    Online Resource
    Online Resource
    Molecular Mechanisms of Retina Pathology and Ways of its Correction (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cytology. ; Pharmacy. ; Biomedical Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cell Biology. ; Pharmacy.
    Description / Table of Contents: Chapter 1. Literature review -- Chapter 2. Results of experimental studies of short peptides (cytogens) in ophthalmology -- Chapter 3. Results of the clinical study of short peptides (cytogens) in ophthalmology -- Conclusion.
    Abstract: This book discusses the pathology of the retina, and reviews current research on the use of cell replacement therapy and short peptides to restore functional activity in retinal neurons. As the book describes, pathologies of the retina, including age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, present a long-standing challenge in the practice of clinical ophthalmology. Modern treatment for these conditions, which lead to irreversible blindness, includes laser exposure, surgical intervention, and drugs. These treatments aim to reduce the risk of new complications in the eye; pathogenetic therapy of degenerative diseases of the retina is practically absent in current ophthalmic practice. The first section of the book reviews the molecular mechanisms of age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, and reports on methods of treatment. The second section presents the results of recent experimental studies of the effects of short peptides on pluripotent embryonic cells; on proliferative activity in retinal cells and pigment epithelium; on expression of markers of differentiation or retinal neurons and pigment epithelium; and on the course of hereditary retinal pigmentation in Campbell rats. The third section offers results of clinical studies on the effectiveness of short peptides in patients with macular degeneration, and in patients with retinitis pigmentosa. The author concludes that the regular use of peptides in the treatment of degenerative diseases of the retina can slow the progression of the pathological process and preserve the patient’s vision for some 10-15 years. In addition, in 80 percent of patients, it is possible to increase visual function by increasing visual acuity, improving the boundaries of the visual field and the fundus.
    Type of Medium: Online Resource
    Pages: VI, 90 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030501600
    URL: https://doi.org/10.1007/978-3-030-50160-0
    DOI: 10.1007/978-3-030-50160-0
    DDC: 610.72
    Language: English
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  • 5
    Online Resource
    Online Resource
    Autophagy: Biology and Diseases : Clinical Science (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Medical sciences. ; Pharmacology. ; Biomedical Research. ; Cell Biology. ; Health Sciences. ; Pharmacology.
    Description / Table of Contents: Autophagy and Alzheimer’s Disease -- Autophagy and Parkinson’s Disease -- Autophagy and Motor Neuron Diseases -- Autophagy and Prion Disease -- Autophagy and Lysosome Storage Disorders -- Autophagy and Mitochondrial Encephalomyopathies -- Autophagy and Ischemic Stroke -- Autophagy and Hemorrhagic Stroke -- Autophagy and Polyglutamine Disease -- Autophagy and Epilepsy -- Autophagy in Neurodevelopmental Disorders -- Autophagy and Pituitary Adenoma -- Autophagy in Schizophrenia -- Autophagy and Hypertension -- Autophagy and Myocardial Ischemia -- Autophagy and Heart Failure -- Autophagy, Myocarditis and Cardiomyopathy -- Autophagy, Hyperlipidemia and Atherosclerosis -- Application of Autophagy in Cardiovascular Diseases -- Autophagy and Tumorigenesis -- Autophagy and Tumour Stem Cells -- Autophagy and Tumour Metastasis -- Autophagy and Tumor Cell Death -- Autophagy and Tumour Chemotherapy -- Autophagy and Tumour Radiotherapy -- Autophagy and Inflammatory Diseases -- Autophagy and Immune-related Diseases -- Autophagy and Autoimmune Diseases -- Autophagy and Bacterial Infection -- Autophagy and Viral Infection -- Autophagy and Thyroid Disease -- Autophagy and Obesity and Diabetes -- Autophagy and Obesity-related Reproductive Dysfunction -- Autophagy and Acute Kidney Injury -- Autophagy and Glomerular Diseases -- Autophagy and Diabetic Nephropathy -- Autophagy and Liver Diseases -- Autophagy and Gastrointestinal Diseases -- Chronic Obstructive Pulmonary Disease and Autophagy -- Autophagy and Pulmonary Fibrosis -- Asthma and Autophagy -- Autophagy and Other respiratory diseases -- Autophagy and Leukemia -- Autophagy and Lymphoma -- Autophagy and Myeloma -- The Function and Mechanisms of Autophagy in Traumatic Brain Injury -- The Function and Mechanisms of Autophagy in Spinal Cord Injury -- The Function and Mechanisms of Autophagy in Trauma of Other Parts of the Body -- The Prospects of Therapeutic Potential and Drug Development Targeting Autophagy in Cancer -- Progress of Anti-aging Drugs Targeting Autophagy -- Drug Development and Treatment of Autophagy in Other Diseases -- Systems Biology Approaches in Autophagy Research -- Natural Product Regulates Autophagy in Cancer -- Regulation of Autophagy in Neurodegenerative Diseases by Natural Products -- Regulation of Autophagy in Cardiovascular Diseases by Natural Products.
    Abstract: This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine.
    Type of Medium: Online Resource
    Pages: XXXVI, 736 p. 50 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811542725
    Series Statement: Advances in Experimental Medicine and Biology, 1207
    URL: https://doi.org/10.1007/978-981-15-4272-5
    DOI: 10.1007/978-981-15-4272-5
    DDC: 610.72
    Language: English
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  • 6
    Online Resource
    Online Resource
    Biological Effects of Static Magnetic Fields (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biomedical Research. ; Cell Biology.
    Description / Table of Contents: Chapter 1. Magnetic Field Parameters and Biological Sample Differences that Lead to Differential Bioeffects -- Chapter 2. Static Magnetic Field Direction-induced Differential Biological Effects -- Chapter 3. Magnetic Properties of Biological Samples -- Chapter 4. Molecular Mechanisms for Electromagnetic Field Biosensing -- Chapter 5. Controlling Cell Membrane Potential with Static Non-uniform Magnetic Fields -- Chapter 6. Impact of Static Magnetic Fields on Cells -- Chapter 7. Impact of Static Magnetic Fields on Microorganisms, Plants and Animals -- Chapter 8. Static Magnetic Fields on Human Bodies -- Chapter 9. Potential Applications of Static Magnetic Fields in Cancer Treatment -- Chapter 10. Effects of Static Magnetic Fields on Diabetes and Its Complications -- Chapter 11. Impacts of Static Magnetic Field on Bone Health -- Chapter 12. Effects of Static Magnetic Fields on the Immune System -- Chapter 13. Biological Effects of Static Magnetic Fields on the Nervous System -- Chapter 14. The Biological Effects of Long-term Static Magnetic Field Exposure -- Chapter 15. Prospects, Pitfalls, and Opportunities for Human Static Magnetic Field Therapy.
    Abstract: The book summarizes the emerging topic about the effects of SMF on biological samples ranging from single molecules, subcellular compartments, and cells to whole organisms. It also discusses the potential application of SMF in clinical treatment of cancer, pain, diabetes and other diseases. With the development and growing popularity of modern appliances like MRI in hospitals, the potential impact of magnetic fields on human health is invoking increasing concerns. At the same time, SMF has been explored in the treatment of tumor and other diseases for decades. Nevertheless, there are still some reservations and uncertainties about these treatments, which are largely due to the differential biological effects reported in the literature. These experimental inconsistencies are mainly caused by variations such as different magnetic field types, intensities, treatment time, as well as biological samples examined. The second edition added eight new chapters about new progress in this field including impacts of SMFs, magnetism of biomolecules, and potential of SMFs in the management of bone, pain, diabetes, and immune systems. This volume will help clarify some dilemmas in this field and encourage further investigations in order to achieve a better understanding of the biological effects of SMF, aiming for a rational application of SMF in clinical therapy in the near future. The book is useful for scientists, doctors, and students who are interested in magnetic fields and life sciences.
    Type of Medium: Online Resource
    Pages: XV, 420 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811988691
    URL: https://doi.org/10.1007/978-981-19-8869-1
    DOI: 10.1007/978-981-19-8869-1
    DDC: 610.72
    Language: English
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  • 7
    Online Resource
    Online Resource
    Myosins : A Superfamily of Molecular Motors (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Proteins . ; Cytology. ; Proteins. ; Biomedical Research. ; Protein Biochemistry. ; Cell Biology. ; Proteins.
    Description / Table of Contents: Introduction -- Myosin Structure -- Cargo Binding by Unconventional Myosins -- Cryo-EM of Actin-Myosin Structures -- Small Molecule Effectors of Myosin Function -- Single-Molecule Biophysical Techniques to Study Actomyosin Force Transduction -- High-Speed Atomic Force Microscopy to Study Myosin Motility -- How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches -- How Actin Tracks Affect Myosin Motors -- Myosins in the Nucleus -- Myosins in Cytokinesis -- Myosins and Disease -- Myosins and Hearing -- The Actomyosin Systems in Apicomplexa -- Approaches to Identify and Characterise MYO6-Cargo Interactions -- Class IX Myosins: Motorized RhoGAP Signaling Molecules -- Myosin X -- Myosin XVI -- Myosin XVIII -- Myosin XIX.
    Abstract: Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular activities including cell structure, cell migration, intracellular trafficking, and cell-cell contact. Importantly, loss of function and mutation are associated with diseases including myopathies, hearing impairment, glomerulosclerosis, and cancer. Written by international experts in myosin motors and the approaches used to study them, this book is expected to provide a comprehensive assessment of the current status of our understanding of the structure and molecular mechanism of myosins and their cellular roles.
    Type of Medium: Online Resource
    Pages: XI, 455 p. 116 illus., 97 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030380625
    Series Statement: Advances in Experimental Medicine and Biology, 1239
    URL: https://doi.org/10.1007/978-3-030-38062-5
    DOI: 10.1007/978-3-030-38062-5
    DDC: 610.72
    Language: English
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  • 8
    Online Resource
    Online Resource
    Microfluidics and Multi Organs on Chip (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biomedical engineering. ; Toxicology. ; Cytology. ; Biomedical Research. ; Biomedical Devices and Instrumentation. ; Toxicology. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Historical and Technological Background to Organs-on-a-Chip -- Chapter 2. Applications of microfluidics -- Chapter 3. Microfluidics based Organ-on-a-chip for cell biology studies -- Chapter 4. Microfluidics in Chemical biology -- Chapter 5. Role of microfluidics in drug delivery -- Chapter 6. Microfluidics in drug discovery -- Chapter 7. Microfludic based sensors -- Chapter 8. Background and Organs-on-a-Chip -- Chapter 9. Culture and co-culture of cells for multi organ on chip -- Chapter 10.Cells and organs on a chip in biomedical sciences -- Chapter 11. Futuristic aspects of organ on a chip -- Chapter 12. Development of Human on a chip -- Chapter 13. Multi-organ on a chip for personalized medicine -- Chapter 14. Development and application of Microfluids in organoid formation -- Chapter 15. Liver on a chip -- Chapter 16. Placenta on Chip: A Modern approach to probe feto-maternal interface -- Chapter 17. Microfluidic retina-on-chip -- Chapter 18. Heart on a chip -- Chapter 19. Kidney on a chip -- Chapter 20. Lungs on a chip -- Chapter 21. Brain on a chip -- Chapter 22. Skin on a chip -- Chapter 23. Organs-on-a-chip in preclinical studies -- Chapter 24. Application of organ on chip in blood brain barrier model -- Chapter 25. Multi organs on a chip in disease modeling -- Chapter 26. Prospects of Medical device on a chip -- Chapter 27. Lab on a chip for precision Medicine -- Chapter 28. Tumour-on-a-chip : Perfusion systems to model the extracellular breast tumour microenvironment:from tumour progression to metastasis formation -- Chapter 29. Building Human In Vitro 3D Models to Replace Animal Studies: During Drug Discovery Reearch: Scientific, Ethical and Regulatory Considerations.
    Abstract: This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
    Type of Medium: Online Resource
    Pages: IX, 717 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811913792
    URL: https://doi.org/10.1007/978-981-19-1379-2
    DOI: 10.1007/978-981-19-1379-2
    DDC: 610.72
    Language: English
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  • 9
    Online Resource
    Online Resource
    Glycosignals in Cancer : Molecular Assembly and Recognition (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Life sciences. ; Cytology. ; Internal medicine. ; Biomedical Research. ; Medical Genetics. ; Life Sciences. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: Part I. Search for novel tumor epitopes related to carbohydrates -- Chapter 1.1. The ganglioside structures: chemistry and biochemistry -- Chapter 1.2. Fucosylated proteins as cancer biomarkers -- Part II. Assembly of glycoconjugates -- Chapter 2.1. Siglec-7 and synthetic sialylpolymer -- Chapter 2.2. Role of Sialyl-Tn antigen in Cancer Metastasis -- Chapter 2.3. Insights into the Role of Chondroitin Sulfate in Cancer -- Part III. Signaling pathways modulated by glycosylation -- Chapter 3.1. Significance of FUT8in pancreatic cancer and others -- Chapter 3.2. Effects of Bullfrog sialic acid-binding lectin in cancer cells -- Part IV. Interaction between carbohydrate and carbohydrate-recognizing molecules -- Chapter 4.1. Opposite functions of mono- and disialylated glycosphingolipids on the membrane of cancer cells -- Chapter 4.2. Tumor progression through interaction of mucins with lectins and subsequent signal transduction -- Part V. Clinical trials targeting glycosignals -- Chapter 5.1. Immunotherapy of Neuroblastoma Targeting GD2 and Beyond.
    Abstract: This book, now in an extensively revised second edition, provides a comprehensive summary of the latest knowledge regarding glycosignals and a thorough analysis of their involvement in not only cancers but also other refractory conditions such as chronic inflammatory disorders. Many relevant topics are covered, including the search for novel tumor epitopes related to carbohydrates, the assembly of glycoconjugates, the modulation of signaling pathways by glycosylation, and interactions between complex carbohydrates and their recognition molecules. The role of various research approaches, for example advanced mass spectrometry, high-resolution imaging, and bioinformatics, is closely examined, and the results of novel therapeutic trials targeting glycosignals are discussed. The book will be essential reading for students and young researchers with an interest in glycoscience. In presenting new results and approaches and identifying areas for future research, it will also be of benefit for specialists in the field.
    Type of Medium: Online Resource
    Pages: VI, 238 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811977329
    URL: https://doi.org/10.1007/978-981-19-7732-9
    DOI: 10.1007/978-981-19-7732-9
    DDC: 610.72
    Language: English
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  • 10
    Online Resource
    Online Resource
    Nuclear Receptors in Human Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Molecular biology. ; Metabolism. ; Genetics. ; Cytology. ; Biomedical Research. ; Molecular Biology. ; Metabolism. ; Genetics and Genomics. ; Cell Biology.
    Description / Table of Contents: Introduction (Moray J Campbell & Charlotte L Bevan) -- Overview (Jason Carroll) -- Part I: Reproduction and Development -- Chapter 1. Nuclear receptors in pregnancy and outcomes: clinical perspective (Luiza Borges Manna & Catherine Williamson) -- Chapter 2. Female Reproductive Systems: hormone dependence and receptor expression (Philippa TK Saunders) -- Chapter 3. Nuclear receptors in ovarian function (Darryl Russell & Doan Thao Dinh) -- Part II: Metabolism -- Chapter 4. Nuclear receptors in energy metabolism (Alina Walth, Stephan Herzig & Maria Rohm) -- Chapter 5. Nuclear Receptors and lipid sensing (James L Thorne and Giorgia Cioccoloni) -- Part III: Central Systems -- Chapter 6. Corticosteroid receptors in Cardiac health and disease (Jessica Ivy, Gillian Gray, Megan Holmes, Martin Denvir, Karen Chapman) -- Chapter 7. Physiological convergence and antagonism between GR and PPARγ in inflammation and metabolism (Marija Dacic, Gayathri Shibu and Inez Rogatsky) -- Chapter 8. Circadian Rhythm and Nuclear Receptors (David W Ray) -- Chapter 9. Vitamin D and gut health (James C Fleet) -- Part IV: Cancer -- Chapter 10. Estrogen Receptor alpha and ESR1 Mutations in Breast Cancer (Jaymin Patel & Rinath Jeselsohn) -- Chapter 11. AR structural variants and prostate cancer (Laura Cato) -- Chapter 12. ERβ and inflammation (Linnea Hases, Amena Archer & Cecilia Williams) -- Chapter 13. Genomic insights into non-steroidal nuclear receptors in prostate and breast cancer (Sajad A Wani & Moray Campbell) -- Part V: New developments in transcriptional control by nuclear receptors -- Chapter 14. Protein condensation in the nuclear receptor family; implications for transcriptional output (Monique Appelman, Elle Hollaar, Jurian Schuijers & Saskia WC van Mil) -- Chapter 15. Prostate cancer epigenetic plasticity and enhancer heterogeneity: molecular causes, consequences and clinical implications (Jeroen Kneppers, Andries M Bergman & Wilbert Zwart) -- Chapter 16. Epigenetic coregulation of androgen receptor signaling (Rayzel Fernandes, Damien A. Leach & Charlotte Bevan) -- Part VI: Clinical Translation -- Chapter 17. Cllnical Translation: Targeting the Estrogen Receptor (Jennifer O. Lauchle & Ciara Metcalfe) -- Chapter 18. Drugging the undruggable: targeting the N-terminal domain of nuclear hormone receptors (Marianne Sadar) -- Chapter 19. Genetic Variation and Mendelian Randomization approaches (Mojgan Yazdanpanah, Nahid Yazdanpanah & Despoina Manousaki) -- Index.
    Abstract: This book addresses and dissects the roles and crosstalk mechanisms for the 48 human nuclear receptors (NR) in human health and disease. After a State-of-the-Art introduction by an undisputed and celebrated field leader to provide an overview of the field and its significance, chapters are organized into six sections. The first three sections discuss NR roles in Reproduction & Development, Metabolism and Central Systems. These present to the reader our current understanding of NR signaling in the development and functioning of the reproductive system; the roles in the regulation of energy metabolism; and how NR signaling is more widely integrated into systemic functions from calcium flux to circadian rhythm. The subsequent three sections dissect how aberrant NR functions drive Cancer; how new insights into Genomic Interaction are helping to reveal how NR disruption drives disease; and finally, how Translational Efforts are exploiting this understanding from developing novel NR ligands to establishing how underlying genetic variation impacts NR function. Within these sections the chapters also illustrate emerging understanding of how the epigenome and non-coding genome combine to regulate NR function and impact dysfunction. Increasingly these insights cross-fertilize over cell and disease boundaries and it is unsurprising that NR are being explored in novel and new arenas such as the context of neurological disorders and depression. Thus, there is wide scope for re-purposing of licensed drugs and development of new NR-targeting therapies for a host of conditions and diseases. This unique book brings together many of the leading figures in NR research from across the globe, to discuss emerging roles and their implications for human health and disease. It summarizes the state of the art and shows signposts for future research to further shape this influential field.
    Type of Medium: Online Resource
    Pages: XII, 346 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031118364
    Series Statement: Advances in Experimental Medicine and Biology, 1390
    URL: https://doi.org/10.1007/978-3-031-11836-4
    DOI: 10.1007/978-3-031-11836-4
    DDC: 610.72
    Language: English
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  • 11
    Online Resource
    Online Resource
    Heat Shock Proteins in Human Diseases (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Proteins . ; Cytology. ; Biomedical Research. ; Protein Biochemistry. ; Cell Biology.
    Description / Table of Contents: Inter-Relationship Between the Inflammation and Heat Shock Protein in Cancer Development: A Possible Target for Diagnosis and Cancer Immunotherapy -- Chaperonin Hsp60 and Cancer Therapies -- Combined Thermotherapy and Heat Shock Protein Modulation for Tumor Treatment -- Small Molecule Inhibitors Targeting Heat Shock Response Pathways: Lessons from Clinical and Preclinical Studies in Cancer Therapeutics -- Multifaceted Roles of Heat Shock Factor 1 (HSF1) in Cancer -- Exploring the Role of Heat Shock Proteins in the Development of Gastric Cancer -- Heat Shock Proteins in Atrial Fibrillation -- Threading Microarrays into Novel Applications -- Regulation of Kaposi’s Sarcoma-associated Herpesvirus Biology by Host Molecular Chaperones -- Role of Heat Shock Factors in Diseases and Immunity -- Heat Shock Proteins and Pain -- Regulates Cellular Senescence: Role of the DHRS2-MDM2-p53 Pathway -- Huntingtin Yeast Two-Hybrid Protein K (HYPK): An Intrinsically Unstructured Heat Shock Inducible Protein with diverse Cellular and Molecular Functions -- Roles of Heat Shock Proteins on Antigen Presentation -- Heat shock proteins mediate anastasis and plasticity of thermotolerant cells.
    Abstract: The book Heat Shock Proteins in Human Diseases provides the most comprehensive review on contemporary knowledge on the role of heat shock proteins (HSP) in various types of human diseases including cancer, cardiovascular disease, microbiology and inflammation. These diseases were specifically chosen due to their dismal prognosis, the survival benefit offered by the current standards do not greatly impact the overall survival statistics with the disease and are associated with toxicity. Using an integrative approach, the contributors provide a synopsis of the most current updates on the state of HSP in human diseases. Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.
    Type of Medium: Online Resource
    Pages: IX, 297 p. 31 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030622893
    Series Statement: Heat Shock Proteins, 21
    URL: https://doi.org/10.1007/978-3-030-62289-3
    DOI: 10.1007/978-3-030-62289-3
    DDC: 610.72
    Language: English
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  • 12
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    Online Resource
    Oxidative Stress : Human Diseases and Medicine (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Pharmacology. ; Biomedical Research. ; Cell Biology. ; Pharmacology.
    Description / Table of Contents: Oxidative stress and anti-oxidant strategies in human diseases -- Oxidative stress in the tumorimmune microenvironment -- Oxidative stress-mediated stem cell aging -- Stress proteins: Biological functions, human diseases and virus infections -- Importance of mitochondrial quality controls in Parkinson’s disease: the potential interplay of mitochondrial unfolded protein response and mitophagy -- Autophagy in cellular stress responses -- Cysteine metabolism in cancer progression and therapy resistance -- Stress and circadians -- ROS, glucose and lipid metabolism -- Drug repurposing: An avenue towards stress medicine in cancer therapy -- Redox regulation of metabolic enzymes in cancer -- Stress and inflammation -- Oxidative stress in cell signaling and cell fate determination under glucose starvation.
    Abstract: This book offers a systematic review of the cutting-edge knowledge in stress medicine. Cellular redox imbalance, resulting from overproduction of reactive oxide species (ROS), leads to oxidative stress and subsequent occurrence and development of many diseases, such as cancer, diabetes, pain, etc. In addition, ROS can induce post-translational modification of proteins and play roles through redox signaling pathways. In this book, the authors attempt to re-define the key concepts in oxidative stress, such as oxidative eustress and oxidative distress, revisit the pivotal signaling of oxidative stress in human diseases, and discuss the debate in current anti-oxidant strategies, such as natural products and drug repurposing. This book serves as a reference to graduate students and researchers in this growing field.
    Type of Medium: Online Resource
    Pages: VI, 323 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811605222
    URL: https://doi.org/10.1007/978-981-16-0522-2
    DOI: 10.1007/978-981-16-0522-2
    DDC: 610.72
    Language: English
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  • 13
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    Online Resource
    Ferroptosis: Mechanism and Diseases (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical genetics. ; Cytology. ; Lipids. ; Biomedical Research. ; Medical Genetics. ; Cell Biology. ; Cell Biology. ; Lipidology.
    Description / Table of Contents: Foreword -- Ferroptosis: Concepts and Definitions -- Overcoming Therapeutic Challenges for Pancreatic Ductal Adenocarcinoma with xCT inhibitors -- Iron Homeostasis and Metabolism: Two Sides of a Coin -- The Role of NCOA4-mediated Ferritinophagy in Ferroptosis -- Emerging Role for Ferroptosis in Infectious Diseases -- Small Molecule Regulators of Ferroptosis -- Necroptosis, The other main Caspase-Independent Cell Death.
    Abstract: This book focuses on the emerging role of ferroptosis in human diseases. It gives a detailed perspective on how to induce or suppress ferroptosis to treat challenging conditions such as infectious diseases, including COVID-19, tuberculosis, parasitic diseases and cancer. The book serves as a practical guide by providing a valuable collection of all currently known activators or inhibitors of ferroptosis. It will enable readers to choose molecules for experimental design for in vitro and in vivo studies of ferroptosis. Furthermore, this volume highlights the aspects of iron metabolism and its connection to ferritinophagy, a ferritin selective autophagy, with profound implications in neurodegenerative diseases such as Alzheimer, Parkinson, Huntington and ALS. Lastly, it describes necroptosis, another important form of cell death, along with its connections to human disorders and potential crosstalk with ferroptosis. While covering basic concepts, the book delves into mechanisms and modulation of ferroptosis for treating a wide variety of human diseases thus offering a valuable and informative resource for both, scientists and clinical researchers.
    Type of Medium: Online Resource
    Pages: IX, 140 p. 37 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030620264
    Series Statement: Advances in Experimental Medicine and Biology, 1301
    URL: https://doi.org/10.1007/978-3-030-62026-4
    DOI: 10.1007/978-3-030-62026-4
    DDC: 610.72
    Language: English
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  • 14
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    Online Resource
    Inflammation and Metastasis (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Medicine Research. ; Biology Research. ; Human physiology. ; Immunology. ; Cytology. ; Biomedical Research. ; Human Physiology. ; Immunology. ; Cell Biology.
    Description / Table of Contents: Chapter 1 General Thinking About Inflammation -- Chapter 2 Inflammation from the Standpoint of Leukocytes -- Chapter 3 Vessels and Coagulation -- Chapter 4 Sterile Inflammation -- Chapter 5 Issue of Self and Non-self -- Chapter 6 Extension of Endogenous Field -- Chapter 7 Evidence for Existence of Endogenous TLR4 Ligands -- Chapter 8 Autoinflammatory Disorders -- Chapter 9 Cancer in General -- Chapter 10 Basic Research -- Chapter 11 Tumor Microenvironment -- Chapter 12 Whole-Body Matter -- Chapter 13 Premetastatic Microenvironment -- Chapter 14 What Is Homeostasis? -- Chapter 15 Explanation of Metastasis by Homeostatic Inflammation -- Chapter 16 Therapeutic Potential.
    Abstract: This book, now in a thoroughly revised and updated second edition, provides the latest information on cancer metastasis from the perspective of inflammation and presents new ideas on the complicated mechanisms of metastasis and potential therapeutic targets. Key features include discussion of mechanisms recently identified to be involved in the resolution phase of inflammation, presentation of the latest evidence regarding the roles of endogenous TLR4 ligands in metastasis, and thorough explanation of the concept of homeostatic inflammation and current understanding of the significance of its dysregulation for metastasis. Structure-based thinking is another important element of the book, and it is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, at the center of which cancer is located. Examples of the many additional specific topics covered in this edition include the functional involvement of new types of RNA in cancer, the insights offered by recent advances in bioinformatics, and the potential of a casein kinase 1α inhibitor in the treatment of acute myeloid leukemia. The book will be a valuable update and resource for both experienced and younger researchers. Homeostasis, originated from an idea of internal milieu by Claude Bernard, is eventually maintained by endogenous elements. The essential features of inflammation are leukocyte mobilization and increased vascular permeability, which could take place in many homeostatic or physiological conditions at low levels. Homeostatic inflammation is a concept to explain pathological settings such as metastasis in which irrespective of its level those inflammatory features are misused with endogenous molecules (see Chap. 14,15). As inflammation comprises many biological fields, targeting a single molecule for a disease could potentially make a therapeutic contribution to other diseases. For example, one focus is applied here to the roles of calprotectin in lung metastasis, which is implicated in psychiatric disorders and COVID-19 as shown by recent evidence.
    Type of Medium: Online Resource
    Pages: XX, 518 p. 81 illus., 33 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9789811617577
    URL: https://doi.org/10.1007/978-981-16-1757-7
    DOI: 10.1007/978-981-16-1757-7
    DDC: 610.72
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  • 15
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    Online Resource
    Cell Culture Engineering and Technology : In appreciation to Professor Mohamed Al-Rubeai (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biology Technique. ; Regenerative medicine. ; Biomedical engineering. ; Biomedical Research. ; Cell Biology. ; Biological Techniques. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Biopharmaceuticals Produced from Cultivated Mammalian Cells -- Remote Control of Mammalian Therapeutic Designer Cells -- Next generation cell engineering using microRNAs -- An Omic’s data-driven approach towards engineering mammalian cell factories and bioprocesses for biopharmaceutical production -- Redesigning spent media from cell culture bioprocess to feed new bacterial fermentations -- Monoclonal antibody glycoengineering for biopharmaceutical quality assurance -- Next-generation cell engineering platform for improving recombinant protein production in mammalian cells -- Manufacturing human pluripotent stem cells and differentiated progenitors -- Biomanufacturing of Mesenchymal Stromal Cell for Therapeutic Applications -- Process Design for hMSC Products in Stirred Tank Bioreactors -- Bio-production of Adeno-associated virus for gene therapy -- Scale-up (and scale-down) of CHO cell culture, with a focus on how to adjust the various culture parameters/setpoints across different systems from lab-scale to manufacturing-scale -- Intensified and Continuous mAb Production with Single-Use Systems -- Mathematical modelling of cell culture processes -- Model-assisted design concepts for mammalian cell culture processes -- Bioprocess monitoring and control -- Industrial Monitoring of Cell Culture.
    Abstract: This contributed volume is dedicated towards the progress achieved within the last years in all areas of Cell Culture Engineering and Technology. It comprises contributions of active researchers in the field of cell culture development for the production of recombinant proteins, cell line development, cell therapy and gene therapy, with consideration of media development, process scale-up, reactor design, monitoring and control and model-assisted strategies for process design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. This book is conceived for graduate students, postdoctoral fellows and researchers interested in the latest developments in Cell Engineering.
    Type of Medium: Online Resource
    Pages: X, 550 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030798710
    Series Statement: Cell Engineering, 10
    URL: https://doi.org/10.1007/978-3-030-79871-0
    DOI: 10.1007/978-3-030-79871-0
    DDC: 610.72
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  • 16
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    Online Resource
    Emerging Contaminants Vol. 2 : Remediation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Environmental chemistry. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Environmental Chemistry. ; Waste Management/Waste Technology.
    Description / Table of Contents: Preface -- Chapter 1 Emerging Contaminants: Remediation -- Chapter 2 Electrochemical Treatments for the Removal of Emerging Contaminants -- Chapter 3 Technologies to Remove Selenium From Water and Wastewater -- Chapter 4 Advanced Treatments for the Removal of Alkylphenols and Alkylphenol Polyethoxylates from Wastewater -- Index.
    Abstract: Emerging contaminants are chemical and biological agents for which there is growing concern about their potential health and environmental effects. The threat lies in the fact that the sources, fate and toxicology of most of these compounds have not yet been studied. Emerging contaminants, therefore, include a large number of both recently discovered and well-known compounds such as rare earth elements, viruses, bacteria, nanomaterials, microplastics, pharmaceuticals, endocrine disruptors, hormones, personal care products, cosmetics, pesticides, surfactants and industrial chemicals. Emerging contaminants have been found in many daily products, and some of them accumulate in the food chain. Correlations have been observed between aquatic pollution by emerging contaminants and discharges from wastewater treatment plants. Most actual remediation methods are not effective at removing emerging contaminants. This second volume presents comprehensive knowledge on emerging contaminants with a focus on remediation.
    Type of Medium: Online Resource
    Pages: XVI, 401 p. 65 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030690908
    Series Statement: Environmental Chemistry for a Sustainable World, 66
    URL: https://doi.org/10.1007/978-3-030-69090-8
    DOI: 10.1007/978-3-030-69090-8
    DDC: 551.48
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  • 17
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    Online Resource
    Climate Impacts on Water Resources in India : Environment and Health (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental health. ; Environmental monitoring. ; Bioclimatology. ; Refuse and refuse disposal. ; Water. ; Environmental Health. ; Environmental Monitoring. ; Climate Change Ecology. ; Waste Management/Waste Technology.
    Description / Table of Contents: Foreword -- Preface -- 1. Water Pollution and Water Quality Assessment, Environmental Flows -- 2. Water Treatment Technologies and Management -- 3. Climate Change and Climate Variability -- 4. Water and Human Health Issues -- 5. Conclusions. .
    Abstract: This book chiefly focuses on environmental flow, water pollution and water quality. Several chapters also cover water treatment technologies and management. In today’s context, climate change and climate variability are important issues in the water sector, which is called upon to develop adaptation strategies to cope with their negative impacts. Human health depends upon the quality of water used for drinking and irrigation purposes. These core issues are discussed and addressed in several chapters. The book explores the impact of climate change on water resources and considers various climatological scenarios. In this regard, it carries out a trend analysis and compares the performance of various Global Climate Models (GCMs). Further, it conducts a water quality analysis and water quality mapping so as to provide information on the most vulnerable areas in the context of water quality. Emerging pollutants, generated from paper mills, are identified in order to choose an appropriate treatment technology. Bioremediation techniques are included for the characterization of improved water quality parameters. The book also presents a low-cost treatment technology for fluoride removal, which can help water managers ensure potable water to stakeholders. In terms of maintaining river ecology in the downstream areas of water resources project sites, the book provides a number of case studies on assessment of environmental flows. Advanced treatment technologies that can be highly advantageous for removing water pollutants are presented. Given its scope, the book offers a valuable resource for academics, water resources practitioners, scientists, water managers, environmentalists, administrators, NGOs, researchers and students who are involved in water management with a main focus on water pollution, the environment, climate change and health. .
    Type of Medium: Online Resource
    Pages: XIII, 392 p. 142 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030514273
    Series Statement: Water Science and Technology Library, 95
    URL: https://doi.org/10.1007/978-3-030-51427-3
    DOI: 10.1007/978-3-030-51427-3
    DDC: 551.48
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  • 18
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    Online Resource
    Thermodynamic and Thermophysical Properties of Saline Water : Models, Correlations and Data for Desalination and Relevant Applications (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Water. ; Hydrology. ; Freshwater ecology. ; Marine ecology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Pollution. ; Refuse and refuse disposal. ; Water. ; Freshwater and Marine Ecology. ; Environmental Engineering/Biotechnology. ; Pollution. ; Waste Management/Waste Technology.
    Description / Table of Contents: Introduction -- Density -- Heat Capacity -- Entropy -- Latent Heat -- Boiling Point Elevation -- Vapor Pressure -- Viscosity -- Thermal Conductivity -- Activity Coefficient -- Osmotic Coefficient -- Surface Tension -- Electrical Conductivity -- Thermal Expansivity -- List of Nomenclature.
    Abstract: This book accommodates the existing correlations, data, and methods for thermodynamic and thermophysical properties of saline water, including multiple components at a wide range of salinity (reaching around 200 g/kg), temperature, and pressure. The correlations of each property are plotted against existing experimental data to judge the comparative accuracy of each within a given specific range of salinity, temperature, and pressure. An assessment to recommend some correlations is also conducted. New correlations for some properties are also proposed. This book helps to provide the saline water properties as needed for engineers, designers, and research for different areas, including desalination and water treatment. All the analytical analysis, thermodynamic analysis, and design models of the desalination technologies depend on saline water properties. As scientists and researchers working on different desalination technologies, the authors found it difficult to find all saline water properties in one source, including multicomponent and binary salty solutions, under different conditions (salinity, temperature, and pressure). Therefore, the authors introduce this book to fill the gap in the open literature. This book compiles the thermodynamic and thermophysical properties of saline water, involving thermodynamic approaches, multicomponent models, and simple correlations and data, comparison between the correlations of properties in figures, recommendation of the most accurate correlations and methods, and the used codes to estimate these correlations and methods. It is expected that this book to be a principal source for all interests in desalination and water treatment subjects.
    Type of Medium: Online Resource
    Pages: XIX, 325 p. 39 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031351938
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-35193-8
    DOI: 10.1007/978-3-031-35193-8
    DDC: 551.48
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  • 19
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    Online Resource
    Wastewater from Olive Oil Production : Environmental Impacts, Treatment and Valorisation (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Chemistry, Technical. ; Biology. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Industrial Chemistry. ; Biological Sciences. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter 1: Valorization of olive tree by-products by co-composting -- Chapter 2: Olive oil mill wastewaters treatment methods -- Chapter 3: Olive mill wastewater: Treatment and valorization -- Chapter 4: Valuable materials from OMW -- Chapter 5: Study the value of olive mill wastewater and their impact on the receiving environment -- Chapter 6: A state-of-art review on the use of olive-oil mill wastewater for human purposes -- Chapter 7: Olive mill waste water bioactive molecules: applications in animal farming -- Chapter 8: Physicochemical characterization and estimation of the pollution degree of olive oil mill wastewaters from the cold extraction system and the traditional system -- Chapter 9: Characterization of top soils subjected to poorly controlled olive oil production wastewater and its effect on litter decomposition -- Chapter 10: Open ponds for effluent storage, a pertinent issue to olive mill wastewater (OMW) management in a circular economy context: Benefits and environmental impact -- Chapter 11: Olive mill wastewaters (OMWWs) a natural tank gorged with bioactive molecules -- Chapter 12: Management of olive oil mill wastewater in Morocco: Production, impacts, and treatment -- Chapter 13: Turkey’s olive mill wastewater (OMWW) problems and some suggestions -- Chapter 14: Future trends in olive industry waste management: A literature review.
    Abstract: This book summarizes the recent research development concerning olive oil wastewater management: characterization, environmental impact, recovery and treatment. The book combines different chapters on the management of olive oil rejects using simple techniques with low investment and operating costs. The main focus of the book is: - Diagnosis, impacts of olive oil waste, and regulations - The valorization of the margins and the olive waste - Wastewater treatment and recovery - Evaluation of investments and operating costs of treatment techniques - Shaped by experience, the authors present their view and approach to each focus area of managing liquid and solid waste produced by crushing units.
    Type of Medium: Online Resource
    Pages: XV, 297 p. 30 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031234491
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-23449-1
    DOI: 10.1007/978-3-031-23449-1
    DDC: 551.48
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  • 20
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    Online Resource
    Ecological Quality Status of Marine Environment : Metal- Sulfide Models; Significance, Mobility, Mechanisms and Impacts (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Environmental chemistry. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Environmental Chemistry. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter I; Introduction to the Significant Impact of AVS on Controlling the Metal Toxicity Regarding Sulfur Cycle -- Chapter II; Chemistry of Sulfur Components and Factors Controlling AVS Concentrations in Marine Environment -- Chapter III; Experimental Approach to Sampling, Storage, Extraction, Determination of AVS-SEM -- Chapter IV; AVS-SEM MODELS -- Chapter V; A Review and an Outlook "AVS- SEM" Studies in Egypt Compared to Aquatic Environment around the World -- Chapter VI; Update, Conclusions, Recommendations, Future Perspective and Challenges.
    Abstract: The goal of this one-of-a-kind book was to provide a critical and in-depth understanding of various AVS-SEM models as predictors for assessing the ecological impact of heavy metals (particularly dibasic cations; Zn, Cd, Ni, Cu, and Pb) on aquatic environments, including the theories underlying these models, descriptive equations, modes of action, methodology, efficiency, applicability, and statistical approaches, as well as comparison with other pollution assessment techniques in the aquatic environments. Metals in interstitial water can be reduced in sediments that co-precipitate with iron (Fe) and manganese (Mn) in FeS or MnS minerals, as well as replace them. This book outlines a system that can be used to track heavy metal contamination in countries with coastal regions that extend over water bodies that are subjected to pollution sources, such as the Mediterranean Basin countries. Moreover, this book will be of great interest to academics, professionals, practitioners, post-graduate students (M.Sc. and Ph.D.), and undergraduates because it gives a clear overview of heavy metal assessment for people interested in environmental studies focusing on the marine environment. It also provides decision-makers with a realistic perspective of the environmental file, allowing them to address environmental issues and directing stockholders to safer locations for environmental activity. From a future perspective, management is advised to overcome the difficulties within that technique, such as accurate handling procedures and different approaches to sampling onshore and offshore. Sequential leaching strategies, especially geochemical fractionation analysis, and knowledge of the interactions and significance of AVS in the marine sector, especially toxicity tests (bioassay) are recommended.
    Type of Medium: Online Resource
    Pages: XXI, 103 p. 41 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031292033
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-031-29203-3
    DOI: 10.1007/978-3-031-29203-3
    DDC: 551.48
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  • 21
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    Online Resource
    Impacts of Urbanization on Hydrological Systems in India (2023)
    Cham :Springer International Publishing :
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    Keywords: Water. ; Hydrology. ; Environmental management. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Refuse and refuse disposal. ; Water. ; Environmental Management. ; Environmental Engineering/Biotechnology. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter1. GIS-based Multi-Criteria Decision Analysis for Identifying Rainwater Harvesting Structures Sites in a Semi-Arid River Basin -- Chapter2. Hydrochemical Investigation and Water Quality Mapping in and around Pallikarnai Marsh Land Area in Chennai, India -- Chapter3. Catchment Scale Modeling of Land Use and Land Cover Dynamics -- Chapter4. Urban Floods: A Case Study of Patna Floods 2019, Natural or Anthropogenic?- Chapter5. Flood Susceptibility Zonation using Dempster-Shafer Evidential Belief Function (EBF) Method in Chalakudy Taluk, Kerala, India -- Chapter6. Impact of Urbanization on Ganga River Basin: An Overview in the Context of Natural Surface Water Resources -- Chapter7. Urban Water Scarcity: A Global Challenge and Impending Solutions -- Chapter8. Groundwater Scarcity in Urban Areas is a Major Issue - Case Studies from West Bengal -- Chapter9. Impact of Urbanization and River Morphology on Groundwater System in Patna Urban Area, Bihar, India -- Chapter10. Aquifer Storage and Recovery: Key Issues and Feasibility -- Chapter11. Temporal Prediction of Groundwater Levels: A Gap in Generalization -- Chapter12. Suitability of Groundwater for Drinking and Agricultural Use in Patna District, Bihar, India -- Chapter13. Groundwater Potential Assessment using GIS-based Weighted Linear Combination Technique: A Case Study of Hard Rock Terrain around Bhopal, India -- Chapter14. The Effect of Urbanization on Groundwater Quality and Hydrochemical Characteristics in Ennore Coastal Aquifers of Chennai, South India -- Chapter15. Groundwater Contamination in Parts of Northwestern Hyderabad- A Hydrogeochemical and Geospatial Approach -- Chapter16. Spatio-Temporal Dynamics of Groundwater Recharge in Dras Sub-Basin of Upper Indus River Basin, Western Himalayas -- Chapter17. Impact of Urbanization on Groundwater in Changing Climatic Scenario: A Case Study.
    Abstract: This book documents the various impacts of urbanization on hydrological systems and water resources. The first half of the book is focused on urbanization and surface waters, starting with the status of hydrological systems in the urban areas, i.e. the catchment characteristics and changes in rainfall dynamics. The most pronounced hydrological problems in cities are changes in runoff due to precipitation. Recently, rain events have been less frequent but more intense, sometimes leading to flash floods. Though the substantial increase in runoff causes floods in the urbanized area, it may be attributed to the reduction of infiltration due to construction of roads. This, in turn, results in groundwater decline and depletion. The second half of the book covers the impact of urbanization on groundwater, which starts with hindered or significantly reduced recharge taking place due to altered urban surfaces. The limited groundwater resources are over-exploited by the urban population, leading to water scarcity and depletion. Groundwater gets polluted due to solid waste dumping sites or by wastewaters discharged by industries. The book will be useful for researchers, educators, municipal/city authorities, government officials, and NGOs.
    Type of Medium: Online Resource
    Pages: XVI, 347 p. 160 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031216183
    URL: https://doi.org/10.1007/978-3-031-21618-3
    DOI: 10.1007/978-3-031-21618-3
    DDC: 551.48
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  • 22
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    Online Resource
    Wastewater Resource Recovery and Biological Methods (2023)
    Cham :Springer International Publishing :
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    Keywords: Water. ; Hydrology. ; Refuse and refuse disposal. ; Environmental management. ; Pollution. ; Renewable energy sources. ; Water. ; Waste Management/Waste Technology. ; Environmental Management. ; Pollution. ; Renewable Energy.
    Description / Table of Contents: Chapter 1. Sustainable utilization of wastewater: an overview -- Chapter 2. Productions of Bioenergy from Wastewater -- Chapter 3. Production of Biogas from wastewater -- Chapter 4. Various treatment technology for generation of Biogas -- Chapter 5. Biohydrogen production from wastewater -- Chapter 6. Various treatment technologies for the generation of biohydrogen from sludge and wastewater -- Chapter 7. Lipid biomass to Biodiesel -- Chapter 8. Biopolymers from wastewater -- Chapter 9. Recovery of nutrients from wastewater -- Chapter 10. Recovery of various metals from wastewater -- Chapter 11. Resource recovery from wastewater -- 12. Biofertilizers from wastewater -- Chapter 13. Microbial fuel cell and wastewater treatment -- Chapter 14. Various applications of Sludge as resources -- Chapter 15. Future research on the sustainable utilization of wastewater as resources -- Chapter 16. Aerobic treatment of high-strength ammonium wastewater-nitrogen removal via nitrate -- Chapter 17. Thermophilic aerobic biological wastewater treatment -- Chapter 18. Aerobic treatment of winery wastewater using jet-loop activated sludge reactor -- Chapter 19. Advancements in the application of aerobic granular biomass technology for sustainable treatment of wastewater.
    Abstract: The book is unique in highlighting the issue of wastewater as one of the important environmental issues. The uniqueness also lies in exploring the concepts of converting waste into resources in the form of bioenergy, biofertilizers through various biological methods. Given the international scenario, the chapters of this book are designed to include both anaerobic and aerobic methods of resource recovery from the industrial wastewater. The book is a step toward design with nature and the concept of green chemistry. Waste menace is one of the most voiced and unsolved problems in the entire world. The whole world is facing the threat of water pollution, soil pollution/ land pollution, odour pollution from the growing waste. Though we find many missions and programs at international, national, and regional level to solve the waste associated issues, this is mostly in context with the solid fraction of the waste. Very little is being done to manage the liquid part of the waste or what we call the wastewater. The conversion of wastewater has the potential to be converted to energy in the form bioenergy, bio-fertilizers, electricity, nutrient recovery, etc. The use of sludge as biofertilizers solves the problem of sludge management on the one hand and production of organic crops on the other. The biological treatment methods like sludge treatment gives the farmers the source of biofertilizers and organic manure for the plants. In the present scenario, energy crisis is also one of the issues that we are facing particularly in context with the thermal power plants which are environmentally highly polluting. Through various techniques like microbial fuel cells or biohydrogen, we get a source of cleaner energy. So, through this book, we try to produce the content and information to give the audience an understanding of the waste water as one of the environmental and health issues and mitigation strategies. The book gives a sufficient understanding of how waste can be turned into a resource.
    Type of Medium: Online Resource
    Pages: VI, 386 p. 47 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031401985
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-40198-5
    DOI: 10.1007/978-3-031-40198-5
    DDC: 551.48
    Language: English
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  • 23
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    Online Resource
    Water in Circular Economy (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Energy policy. ; Energy and state. ; Environmental management. ; Sustainability. ; Refuse and refuse disposal. ; Water. ; Energy Policy, Economics and Management. ; Energy Policy, Economics and Management. ; Environmental Management. ; Sustainability. ; Waste Management/Waste Technology.
    Description / Table of Contents: Water as key resource in Circular Economy -- Impact Of Climate Change on Water Status: Challenges and Emerging Solutions -- Integrated Water Management - Directions of Activities and Policies -- Circular Water Management in Smart Cities -- The Influence of Mineral Parameters on the Geochemistry of Heavy Metals in Bottom Sediments -- Sustainable Water Use in Agriculture - Circular Economy Approach -- Innovative Solutions in the Transition to Circular Economy in Water Sector -- Advanced Treatment Technologies in Removal of Pollutants from Water and Wastewater -- The Role of Water Recycling in Building a Circular Economy in the Textile Industry -- The Role of Water Recycling in Building a Circular Economy in the Textile Industry -- Preliminary Microbiological Risk Assessment for Local Water Reuse in a Small MBR Waste Water Treatment Plant -- Can Remote Sensing be a Useful Tool to Increase Water Reuse in Agriculture? -- Nutrients Recovery in Water and Wastewater Sector -- Technologies for Nutrient Recovery From Municipal Wastewater -- Circular Economy in Domestic and Industrial Waste Waters: Challenges and Opportunities -- Monitoring of Circular Economy Implementation in Water Sector -- Water Footprint of Business and Circular Economy -- Economic, Social and Environmental Dimensions in the Circular Economy (CE) Monitoring Framework in Water and Wastewater Sector -- Circular Economy Indicators and Measures in Water and Wastewater Sector – Case Study -- Business Opportunities in Water and Wastewater Sector as a Part of the Resolve Framework -- Circular Economy Implementation in the Water Sector: Wastewater Treatment Plant Tychy-Urbanowice Case Study -- Wastewater-Based Circular Economy Operations in East Kolkata Wetlands (The Largest Ramasar Site in South Asia), India.
    Abstract: This book presents possible solutions for a circuler economy (CE) in the water and wastewater sector through an inventory of multidisciplinary knowledge with high scientific and practical importance which can contribute to support the transition to the CE model in water and wastewater sector. Water in modern studies exceeds being an important source for irrigation and drinking. It is now a significant source of renewable energy and a catalyst in most industrial and manufacturing products. The protection and sustainable management of water resources and water-based waste (as wastewater, sewage sludge, or sewage sludge ash) are important aspects of the CE, which is defined as a regenerative growth model that gives back to the planet more than it takes. Our book, entitled "Water in Circular Economy", delivers a comprehensive overview of the latest research covering the following aspects of water management from the perspective of the CE implementation: · Water as a key resource in the circular economy; · Innovative solutions in transition to the circular economy in water and wastewater sector; · Monitoring of circular economy implementation in water and wastewater sector.
    Type of Medium: Online Resource
    Pages: IX, 254 p. 106 illus., 81 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031181658
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    URL: https://doi.org/10.1007/978-3-031-18165-8
    DOI: 10.1007/978-3-031-18165-8
    DDC: 551.48
    Language: English
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  • 24
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    Online Resource
    Advances in Nanomaterials-based Cell Biology Research (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Nanobiotechnology. ; Biomedical Research. ; Cell Biology. ; Nanobiotechnology.
    Description / Table of Contents: Chapter 1. Nanomaterials and Stem Cells for Bone Tissue Engineering -- Chapter 2. The Application of Nanomaterial in Skeletal Muscle Regeneration -- Chapter 3. Application of Nanomaterials in Neurodegenerative Diseases -- Chapter 4. Application of Nano Drug Delivery Systems in Inhibition of Tumors and Cancer Stem Cells -- Chapter 5. The Application and Problems of Tetrahedral Framework Nucleic Acids as a Drug Carrier in Biomedicine Fields -- Chapter 6. Research Progress on Antibacterial Application with Nucleic Acid and Nucleic Acid Materials -- Chapter 7. The Application of DNA Nanostructures in Vaccine Technology.-.
    Abstract: This book aims to comprehensively summarize the current research status of nanomaterials and cell biology. It highlights the biological effects and biomedical applications of nanomaterials for specific diseases, bone tissue engineering, and skeletal muscle regeneration. It also provides the details of the biomedical applications of nucleic acid nanomaterials in drug delivery carriers, antimicrobial therapy, vaccine, and neurodegenerative diseases. Therefore, this book renders the audience a better understanding of nanomaterials along with the diverse applications in the cell biology field from recent works to perspectives.
    Type of Medium: Online Resource
    Pages: IX, 219 p. 13 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811626661
    URL: https://doi.org/10.1007/978-981-16-2666-1
    DOI: 10.1007/978-981-16-2666-1
    DDC: 610.72
    Language: English
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  • 25
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    Online Resource
    Principles of Light Microscopy: From Basic to Advanced (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Life sciences. ; Cytology. ; Spectrum analysis. ; Biomedical Research. ; Life Sciences. ; Cell Biology. ; Spectroscopy.
    Description / Table of Contents: Chapter 1. The physical principles of light propagation and light-matter interactions -- Chapter 2. Design, alignment and usage of infinity-corrected microscope -- Chapter 3. Epifluorescence Microscopy -- Chapter 4. Basic digital image design, processing, analysis, management, and presentation -- Chapter 5. Confocal Microscopy -- Chapter 6. Live-cell Imaging: A Balancing Act Between Speed, Sensitivity and Resolution -- Chapter 7. Structured Illumination Microscopy -- Chapter 8. Stimulated Emission Depletion Microscopy -- Chapter 9. Two-Photon Imaging -- Chapter 10. Modern microscopy image analysis: quantifying colocalization on a mobile device -- Chapter 11. Spinning Disk Microscopy -- Chapter 12. Light Sheet Fluorescence Microscopy -- Chapter 13. Localization microscopy: a review of the progress in methods and applications.
    Abstract: This textbook is an excellent guide to microscopy for students and scientists, who use microscopy as one of their primary research and analysis tool in the laboratory. The book covers key microscopy principles and explains the various techniques such as epifluorescence microscopy, confocal/live cell imaging, SIM/light sheet microscopy, and many more. Easy-to-understand protocols provide helpful guidance for practical implementation in various commercially available imaging systems. The reader is introduced to histology and further be guided through advanced image acquisition, classification and analysis. The book is written by experienced imaging specialists from the UK, other EU countries, the US and Asia, and is based on advanced training courses for master students and PhD students. Readers are not expected to be familiar with imaging and microscopy technologies, but are introduced to the subject step by step. This textbook is indented for biomedical and medical students, as well as scientists and postdocs who want to acquire a thorough knowledge of microscopy, or gain a comprehensive overview of modern microscopy techniques used in various research laboratories and imaging facilities. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 324 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031044779
    URL: https://doi.org/10.1007/978-3-031-04477-9
    DOI: 10.1007/978-3-031-04477-9
    DDC: 610.72
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  • 26
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    Online Resource
    Microscopy Techniques for Biomedical Education and Healthcare Practice : Principles in Light, Fluorescence, Super-Resolution and Digital Microscopy, and Medical Imaging (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Medical education. ; Materials Microscopy. ; Anatomy. ; Cytology. ; Education Data processing. ; Biomedical Research. ; Medical Education. ; Microscopy. ; Anatomy. ; Cell Biology. ; Computers and Education.
    Description / Table of Contents: Part I. Advances in Microscopy for Visualization, Education and Healthcare Practice -- Chapter 1. Visualizing the Invisible: Microscopy and How It Affects Our Understanding of Cells and Tissues -- Chapter 2. Morphometric Image Analysis and Its Applications in Biomedicine Using Different Microscopy Modes -- Chapter 3. The Shift in Power from Conventional to Digital and Virtual Microscopy -- Chapter 4. How Visualizations Have Revolutionized Taxonomy: From Macroscopic, to Microscopic, to Genetic -- Chapter 5. Bright New World: Principles of Fluorescence and Applications in Spectroscopy and Microscopy -- Chapter 6. An Introduction to Particle Tracking Techniques with Applications in Biomedical Research -- Chapter 7. An Exploration of the Practice of CT Modalities to Evaluate Anterior Cranial Deformities in Craniosynostosis -- Part II. Anatomical and Cell Biology Education -- Chapter 8. The Use of Biomedical Imaging in Visuospatial Teaching of Anatomy -- Chapter 9. Ultrasound Imaging for Musculoskeletal Research -- Chapter 10. Skill Acquisition in Histology Education.
    Abstract: This edited book has a strong focus on advances in microscopy that straddles research, medical education and clinical practice. These advances include the shift in power from conventional to digital microscopy. The first section of this book covers imaging techniques and morphometric image analysis with its applications in biomedicine using different microscopy modes. Chapters highlight the rich development of fluorescence methods and technologies; particle tracking techniques with applications in biomedical research and nanomedicine; the way in which visualizations have revolutionized taxonomy from gross anatomy to genetics; and the psychology of perception and how it affects our understanding of cells and tissues. The book’s first section concludes by exploring the use of CT modalities to evaluate anterior deformities in craniosynostosis. In the second section of the book, chapters on anatomical and cell biology education explore the history of anatomical models and their use in educational settings. This includes examples in 3D printing and functional human anatomical models that can be created using easily available resources and the use of biomedical imaging in visuospatial teaching of anatomy; the novel use of ultrasound in medical education and practice; and skill acquisition in histology education using a flowchart called a ‘decision tree’. This book will appeal to histologists, microscopists, cell biologists, clinicians and those involved in anatomical education and biomedical visualization, as well as students in those respective fields.
    Type of Medium: Online Resource
    Pages: XIV, 228 p. 107 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031368509
    Series Statement: Biomedical Visualization, 2
    URL: https://doi.org/10.1007/978-3-031-36850-9
    DOI: 10.1007/978-3-031-36850-9
    DDC: 610.72
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  • 27
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    Online Resource
    Cullin-RING Ligases and Protein Neddylation : Biology and Therapeutics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Post-translational modification. ; Cytology. ; Biomedical Research. ; Post-translational Modifications. ; Cell Biology.
    Description / Table of Contents: Chapter 1 Introduction of Protein Ubiquitination and Cullin/RING Ubiquitin Ligases: introduce the protein ubiquitination system briefly; discuss the family of Cullin/RING Ubiquitin Ligases -- Chapter 2 Assembly and Regulation of CRL ubiquitin ligases: discuss the assembly process of CRL ubiquitin ligases by CAND1; elaborate the regulation of CRL ubiquitin ligases by neddylation -- Chapter 3 Protein structure of CRL and Neddylation complex -- Chapter 4 The roles of CRL ubiquitin ligases and neddylation in human diseases -- Chapter 5 The roles of CRL ubiquitin ligases in stem cell biology: Briefly introduce concept and potential application of stem cells; analyze a few example for CRL ubiquitin ligases to control stem cell biology -- Chapter 6 The biology of F-box proteins: introduce the history of SCF ubiquitin ligases; discuss the overall functions of F-box proteins (emphasize phospho-degron concept) -- Chapter 7 The roles of Fbxw7 in human diseases: discuss the roles of Fbw7 in cancer; elaborate the roles of Fbxw7 in other diseases -- Chapter 8 Mouse models of CRL1 components to study their biological function -- Chapter 9 Cullin2 and cancer: introduce Cullin2 ubiquitin ligases; discuss VHL ubiquitin ligase and its roles in cancer -- Chapter 10 Cullin3 and tumorigenesis: introduce Cullin3 ubiquitin ligases; discuss a few examples of Cullin3 ubiquitin ligases in control of tumorigenesis -- Chapter 11 Cullin4-DCAF proteins in tumorigenesis: Discovery of DCAF proteins; discuss a few examples of DCAF’s biological functions -- Chapter 12 Cullin4 ubiquitin ligases in DNA damage responses: Introduce Cullin4 ubiquitin ligases; discuss the roles of Cullin4 ubiquitin ligases in DNA damage responses -- Chapter 13 Coordinating the roles of Cullin5 ubiquitin ligases by SAG and UBE2F: introduce Cullin5 ubiquitin ligases; discuss how SGA and UBE2F mediates the functions of Cullin5 -- Chapter 14 Cullin5 in anti-virus infection: mechanism and drug target -- Chapter 15 The roles of Cul7 in cancer biology: introduce Cullin7 ubiquitin ligase7; discuss a few examples of Cullin7 ubiquitin ligases in cancer -- Chapter 16 Coordinating functions of p97 and CRL ubiquitin ligases in protein turnover: introduce the interactions between p97 and CRL ubiquitin ligases; discuss the coordinating roles between p97 and CRL ubiquitin ligases in protein turnover -- Chapter 17 Interaction between CRL ubiquitin ligases and COP9 Signalosome: introduce Cop9 signalosome; discuss how Cop9 signalosome regulates CRL ubiquitin ligases -- Chapter 18 Drug discovery effort to target Cullin-3 neddylation: discuss inhibitor of Cullin3 neddylation and its application -- Chapter 19 Targeting neddylation modification: Briefly introduce protein neddylation; discuss the roles of neddylation in cancer -- Chapter 20 Targeting CRL ubiquitin ligases: discuss current progress in targeting CRL ubiquitin ligases; discuss the application of CRL ubiquitin ligases in Protac drug development.
    Abstract: This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.
    Type of Medium: Online Resource
    Pages: VIII, 372 p. 119 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811510250
    Series Statement: Advances in Experimental Medicine and Biology, 1217
    URL: https://doi.org/10.1007/978-981-15-1025-0
    DOI: 10.1007/978-981-15-1025-0
    DDC: 610.72
    Language: English
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    Online Resource
    The Extraordinary Biology of the Naked Mole-Rat (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Biology Technique. ; Physiology. ; Evolution (Biology). ; Cytology. ; Vertebrates. ; Biomedical Research. ; Experimental Organisms. ; Animal Physiology. ; Evolutionary Biology. ; Cell Biology. ; Vertebrate Zoology.
    Description / Table of Contents: Dedication -- About the editors -- Preface (Jarvis JUM) -- Chapter 1. Social evolution in African mole-rats - a comparative overview (Faulkes CG & Bennett NC) -- Chapter 2. Social behavior in naked mole-rats: individual differences in phenotype and proximate mechanisms of mammalian eusociality (Holmes MM & Goldman BD) -- Chapter 3. Neuropeptidergic and neuroendocrine systems underlying eusociality and the concomitant social regulation of reproduction in naked mole-rats: a comparative approach (Coen CW, Bennett N, Holmes MM, & Faulkes CG) -- Chapter 4. Adult neural plasticity in naked mole-rats: implications of fossoriality, longevity and sociality on the brain’s capacity for change (Mooney SJ, Forger NG, & Holmes MM) -- Chapter 5. Sensory Systems of the African Naked Mole-Rat (Vice EN, Lagestee S, Browe BM, Deb D, Smith ESJ, Park TJ) -- Chapter 6. Hearing and vocalizations in the naked mole-rat (Barker AJ, Koch, U, Lewin GR, Pyott, SJ) -- Chapter 7. The somatosensory world of the African naked mole-rat (Lewin GR, Smith ESJ, Reznick J, Debus K, Barker A, and Park TJ) -- Chapter 8. The idiosyncratic physiological traits of the naked mole-rat; a resilient animal model of aging, longevity, and healthspan (Buffenstein R and Craft W) -- Chapter 9. African Naked Mole-Rats Demonstrate Extreme Tolerance to Hypoxia and Hypercapnia (Park TJ, Smith ESJ, Reznick J, Bennett NC, Applegate DT, Larson J, Lewin GR) -- Chapter 10. A sweet story of metabolic innovation in the naked mole-rat (Reznick J, Park TJ, and Lewin GR) -- Chapter 11. Insights into the molecular basis of genome stability and pristine proteostasis in naked mole-rats (Narayan V, McMahon M, O’Brien J, McAllister F and Buffenstein R) -- Chapter 12. The Unusual Immune System of the Naked Mole-Rat (Lin TD and Buffenstein R) -- Chapter 13 -- Induced Pluripotent Stem Cells from Cancer-Resistant Naked Mole-rats (Miura. K, Oiwa Y, and Kawamura Y) -- Chapter 14. Naked mole-rats: resistant to developing cancer or good at avoiding it? (Hadi F, Smith ESJ and Khaled WT) -- Chapter 15. Spontaneous Disease and Pathology of Naked Mole-rats (Delaney MA, Imai DM, Buffenstein R) -- Chapter 16. Managed Care of Naked Mole-rats (Smith M, and Buffenstein¬ R) -- Chapter 17. Some exciting future directions for work on naked mole-rats (Smith ESJ, ParkTJ, Holmes MM and Buffenstein R).
    Abstract: This volume focuses on the huge advances in the last 25 years on the use of this animal model for biomedical research (cancer, heart disease and neurodegeneration), fundamental neuroscience and basic subterranean biology. In 2013, Science magazine named the naked mole-rat as the Vertebrate of the Year. This was partly due to research carried out documenting its extreme longevity, negligible senescence, and prolonged maintenance of cancer free, good health well into old age as well as seminal work on mechanisms involved in these processes, pain and hypoxia resistance. In addition to this research focus on longevity and chronic diseases such as cancer and cardiovascular disease, the naked mole-rat has also made a substantial contribution to the fields of ecophysiology, neuroscience and behavior. With international contributions, this book provides a valuable text for zoological students, behavioral scientists and biomedical researchers.
    Type of Medium: Online Resource
    Pages: XIV, 445 p. 188 illus., 139 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030659431
    Series Statement: Advances in Experimental Medicine and Biology, 1319
    URL: https://doi.org/10.1007/978-3-030-65943-1
    DOI: 10.1007/978-3-030-65943-1
    DDC: 610.72
    Language: English
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  • 29
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    Online Resource
    Breakthroughs in Space Life Science Research : From Apollo 16 to the ISS (2021)
    Cham :Springer International Publishing :
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    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Solar system. ; Aerospace engineering. ; Astronautics. ; Biomedical Research. ; Cell Biology. ; Space Physics. ; Aerospace Technology and Astronautics.
    Description / Table of Contents: Chapter 1. Introduction: Space Life Sciences – Basic Research and Applications under Extraordinary Conditions -- Chapter 2. A Long Way for Europe and Germany: From Apollo 16 to the International Space Station ISS -- Chapter 3. Success Stories: Incremental Progress and Scientific Breakthroughs in Life Science Research -- Chapter 4. Success Stories: Innovative Developments for Biomedical Diagnostics and Preventative Health Care -- Chapter 5. Space Life Sciences in the Exploration Era: An Outlook on Future Challenges and Opportunities.-.
    Abstract: This last volume of the SpringerBriefs in Space Life Sciences series is setup in 5 main parts. The 1st part shortly summarizes the history of life science research in space from the late 40s until today with focus on Europe and Germany, followed by a part on describing flight opportunities including the Space Shuttle/Spacelab system and the International Space Station ISS; in the 3rd part it focuses on extraordinary success stories of this constantly challenging research program and highlights some important key findings in space life science research. The book introduces in the 4th part innovative developments in non-invasive biomedical diagnostics and training methods for astronauts that emerge from this program and are of benefit for people on Earth especially in the aging society. Last but not least in its 5th part it closes with an outlook on the future of space life sciences in the upcoming era of space exploration. The book is intended for students and research scientists in the life sciences and biomedicine as well as for interested lay persons, who wish to get an overview of space life science research: its´ early days, current status and future directions.
    Type of Medium: Online Resource
    Pages: XVII, 155 p. 34 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030740221
    Series Statement: SpringerBriefs in Space Life Sciences,
    URL: https://doi.org/10.1007/978-3-030-74022-1
    DOI: 10.1007/978-3-030-74022-1
    DDC: 610.72
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  • 30
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    Online Resource
    Extracellular Vesicles in Cardiovascular and Metabolic Diseases (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Biological transport. ; Cell membranes. ; Biomedical Research. ; Translational Research. ; Cell Biology. ; Membrane Trafficking.
    Description / Table of Contents: Section I. Extraction Methods -- Chapter 1. Updated Methods of Extracellular Vesicles Isolation -- Section II. Extracellular Vesicles in Cardiovascular Disease -- Chapter 2. Extracellular Vesicles and Pathological Cardiac Hypertrophy -- Chapter 3. Extracellular Vesicles and Cardiac Aging -- Chapter 4. Extracellular Vesicles and Ischemic Cardiovascular Diseases -- Chapter 5. Extracellular Vesicles and Hypertension -- Chapter 6. Extracellular Vesicles and Coronary Artery Disease -- Chapter 7. Extracellular Vesicles and Vascular Inflammation -- Chapter 8. Extracellular Vesicles and Muscle Atrophy Treatment -- Section III. Extracellular Vesicles in Metabolic Diseases -- Chapter 9. Extracellular Vesicles and Fatty Liver -- Chapter 10. Extracellular Vesicles and Obesity -- Chapter 11. Extracellular Vesicles in Bone Remodeling and Osteoporosis -- Section IV. Therapeutic Implications -- Chapter 12. Diagnosis of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 13. Therapeutics of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 14. Gene Therapy of Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Section V. Future Prospects -- Chapter 15. Prospective Advances of Extracellular Vesicles Investigation in Cardiovascular and Metabolic Research -- Chapter 16. Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular and Metabolic Diseases -- Chapter 17. Extracellular Vesicle Release from Platelets and their Contributions to Thrombosis.
    Abstract: This book provides the latest research progress on Extracellular vesicles (EVs) in cardiovascular and metabolic diseases. EVs are small bilayer lipid membrane vesicles released by cells and function for intercellular communication. Increasing evidence has shown that EVs play crucial roles in cardiovascular and metabolic diseases, which seriously threaten human health worldwide. The book contains four sections: 1) Extraction Methods; 2) EVs in Cardiovascular Diseases; 3) EVs in Metabolic Diseases; and 4) Therapeutic Implications. This book is useful for biologists, cardiologists, cardiovascular surgeons, endocrinologists, internists, nurses, undergraduate and graduate students in medicine and cell biology, and others interested in cardiovascular and metabolic medicine.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819914432
    Series Statement: Advances in Experimental Medicine and Biology, 1418
    URL: https://doi.org/10.1007/978-981-99-1443-2
    DOI: 10.1007/978-981-99-1443-2
    DDC: 610.72
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  • 31
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    Online Resource
    Instrumentation and Measurement Technologies for Water Cycle Management (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental management. ; Natural disasters. ; Refuse and refuse disposal. ; Water. ; Environmental Management. ; Natural Hazards. ; Waste Management/Waste Technology.
    Description / Table of Contents: Regional Adaptation of Water Quality Algorithms for Monitoring Inland Waters: Case Study from Irish Lakes -- Optical remote sensing in Lake Trasimeno: understanding from applications across diverse temporal, spectral and spatial scales -- Satellite instrumentation and technique for oil pollution monitoring of the seas -- Satellite instrumentation and technique for monitoring of seawater quality -- Inland Water altimetry: technological progress and applications -- Generic Strategy for Consistency Validation of the Satellite-, In-situ-, and Reanalysis - based Climate Data Records (CDRs) Essential Climate Variables (ECVs) -- Optical spectroscopy for on line water monitoring -- Fiber optic technology for environmental monitoring: state of the art and application in the Observatory of transfers in the Vadose Zone- (O-ZNS) -- Plants, vital players in the terrestrial water cycle -- Improving water quality and security with advanced sensors and indirect water sensing methods.
    Abstract: This book aims at presenting a unified framework for the description of working principles, recent advances and applications of cutting-edge measurement technologies for the water sector. Instrumentation and measurement technologies are currently playing a key role in the monitoring, assessment and protection of environmental resources. Measurement techniques and sensing methods for the observation of water systems are rapidly evolving and are requiring an increased multi-disciplinary participation. The whole water sector is characterised by multiple technological contexts concerning the monitoring of the resource, given the broad coverage that includes water from its natural domains to the men-made infrastructures. In particular, instrumentation and measurement technologies have a pervasive presence in all the necessary aspects for the assessment, monitoring and control of the water resource and of its relationship with the various environmental stressors, including the anthropic pressures. Therefore, the book aims at presenting how the diagnostics/monitoring methodologies and the related technologies can give an answer to the issues raised by the complex scenario characterising the water cycle management (WCM). The book is structured in five topical sections, grouped by similarity of their technological and/or applicative contexts.
    Type of Medium: Online Resource
    Pages: IX, 599 p. 250 illus., 213 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031082627
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-031-08262-7
    DOI: 10.1007/978-3-031-08262-7
    DDC: 551.48
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  • 32
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    Online Resource
    Environmental Science and Technology: Sustainable Development : International Conference on Environmental Science and Technology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Climatology. ; Environmental management. ; Sustainability. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Climate Sciences. ; Environmental Management. ; Sustainability. ; Waste Management/Waste Technology.
    Description / Table of Contents: An Ecological-network-analysis Input-output Model for Analyzing Energy Consumption in Fujian Province -- High-accuracy Machine Learning Models to Estimate Above Ground Biomass over Tropical Closed Evergreen Forest Areas from Satellite Data -- An Integrated Bi-level Optimization Model for Planning Water-food-energy Nexus System under Uncertainty -- Evaluating the Effects of Environmental Stress on Leaf Chlorophyll Content as an Index for Tree Health -- Optimizing Water Resources Allocation and Hydropower Generation for Supporting Reservoir Management -- Climate Change Impacts on Agriculture and Water Resource Management in the North China Plain -- Analysis on the Response of Lake Level Changes: a Hybrid Stepwise-cluster Factorial Approach -- A Comparative study of Geometric and Exponential Laws in Modelling the Distribution of Daily Precipitation Duration's -- Planning Water-food-energy Nexus System towards Sustainable Development under Uncertainty -- Assessment of Climate Change Impacts on Streamflow - A case Study of Naryn River Basin, Central Asia -- Multiple Linear Regression Model of environmental variables, predictors of global solar radiation in the area of East Lima, Peru -- Development of a Bayesian Copula-based Spatial-temporal Method for Multivariate Drought Risk Analysis -- Hydro-meteorological Big Data Integration and Application Service in the Yangtze River Basin -- Global INDCs Gap, Dilemma and Innovative Path of Carbon Sink Increase -- What are the Embedded Emissions from Industrial Consumption? -- Sustainable Cities, Rescue of Original Construction Methods and Use of Technology. A Literary Review -- The Impact of Urban Green-infrastructure Development on the Price of Surrounding Real Estate: A case study of Taichung City’s Central District -- Numerical Investigation of a 600 MW Tangentially Fired Boiler with Different Particle Sizes of Pulverized Coal -- Sustainable Energy Planning Based on the Electrical Grid and Green Energy Transition in Kenya between 2019 to 2030. Design, Implementation and Evaluation of an Industrial Water Treatment System in El Coca, Ecuador in Accordance with National Guidelines -- Bio-inspired Hierarchical Porous TiO2 for Photodegradation of Organic Pollutant under Solar Irradiation -- Enhanced Membrane Fouling Control and Trace Organic Compounds Removal by Coupling Coagulation and Adsorption in an Electric Field -- Platinum Nanoparticles Embed in Pt Single Atoms Doped Carbon for Efficient Oxygen Reduction Reaction -- The Influence of Stibnite Grain Size on the Oxidative Dissolution Process and Isotope (S,O) Characteristics -- Contribution of Constructed Wetlands for Reclaimed Water Production: A Review -- Chemical Characteristics and Fluorine Enrichment Mechanism of High Fluoride Groundwater in Aksu Area, Xinjiang -- Pollution Characteristics of VOCs in Atmospheric Background Air of Jinan Cities -- Ultra-selective and room temperature NO2 sensor based on PPy/MXene isotype junction -- Spatio-seasonal variation assessment of water quality based on GIS techniques to identify pollution sources in Mantaro basin -- Enhance the Performance of Electrospun Forward Osmosis Membrane by Introducing a Carbon Nanotube Interlayer -- Applicability of ion exchange with the combination of air stripping for ammonium removal and recovery -- Confining peroxymonosulfate activation in carbon nanotube intercalated nitrogen doped reduced graphene oxide membrane for enhanced water treatment: The role of nanoconfinement effect -- Achieving rapid and deep autotrophic nitrogen removal from wastewater in aeration sponge iron biofilter: Simultaneous nitrification, Feammox, NDFO and Anammox -- Metabolomic pathway regulation to achieve optimal control of inorganic carbon in anammox process -- Essential oils of plants as biocides against microorganisms isolated from Portuguese Convent of Christ in Tomar -- Understanding the biodegradation and impact of metronidazole in mesophilic and thermophilic anaerobic fermentation -- The potential of peripheral neighborhoods for the development of urban green in Latin American cities, the case of Algeria, Quito, Ecuador -- Potential for Nature-based solutions to Mitigate Impacts of Climate Change -- Agritourism and Territorial Development in Rural Areas in Morocco: Impact Study at the Level of the Fes-meknes Region (Morocco).
    Abstract: This book features a collection of high-quality and peer-reviewed papers from 2022 13th International Conference on Environmental Science and Technology, which was held in Shandong, China, during October 21–23, 2022. ICEST is held annually as a platform for presentation of new advances and research results in the fields of Environmental Science and Technology. This year, we focus on the theme: Environmental Protection and Sustainable Development. With the continuous development of human society, environmental problems are becoming more and more serious. How to realize the rational use of resources, realize the sustainable development of ecological environment, and protect the environment on which human beings live has become an urgent problem to be solved. Based on the conference theme this year, the presentations include the topical areas of environmental sustainability, environmental restoration, waste minimization, solid waste management, water pollution control, water treatment and reclamation, air pollution control, carbon capture and storage and environmental monitoring, etc.
    Type of Medium: Online Resource
    Pages: IX, 336 p. 136 illus., 108 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031274312
    Series Statement: Environmental Science and Engineering,
    URL: https://doi.org/10.1007/978-3-031-27431-2
    DOI: 10.1007/978-3-031-27431-2
    DDC: 551.48
    Language: English
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    Online Resource
    Water Quality Modeling That Works (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental chemistry. ; Environmental management. ; Environment. ; Refuse and refuse disposal. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Water. ; Environmental Chemistry. ; Environmental Management. ; Environmental Sciences. ; Waste Management/Waste Technology. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: 1. Challenges of Modeling for Water Quality Management -- 2. Data Analysis to Understand the Modeled System -- 3. River BOD/DO Modeling with New Twists -- 4. Eutrophication Modeling: Algal Blooms, Nutrients, and Dissolved Oxygen -- 5. Modeling Analysis for pH -- 6. Modeling Pathogens in Natural Waters and Sediments -- 7. Toxics and Emerging Chemicals -- 8. Mixing Zone Analysis.
    Abstract: This book offers a practical guidance for environmental engineers and scientists charged with assessing the cause-and-effect of pollutants in receiving water systems. Instead of blindly running models, which is a practice seen too often in today’s field that can result in results with uncertainty, modelers must first understand the physical insights of the specific water systems in order to properly calibrate the parameters of the models. This book reinforces the critical importance of properly understanding the physical attributes of water systems by drawing on the author’s extensive experience in modeling with strong data support. This is also what sets this book apart from the volumes currently available in the water quality modeling field – nearly all other books in the field are categorized as textbooks, and unlike this book, offer few practical examples or exercises to follow. Environmental engineers and scientists engaged in quantifying the water quality impacts of pollutants to specific water systems will find this book valuable in their day-to-day practices. This book is a necessary volume for water quality engineers and scientists to consult for the regulatory planning and management of water systems.
    Type of Medium: Online Resource
    Pages: XVII, 308 p. 176 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030904838
    URL: https://doi.org/10.1007/978-3-030-90483-8
    DOI: 10.1007/978-3-030-90483-8
    DDC: 551.48
    Language: English
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    Online Resource
    Unconventional Water Resources (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental sciences Social aspects. ; Refuse and refuse disposal. ; Agriculture. ; Water. ; Environmental Social Sciences. ; Waste Management/Waste Technology. ; Agriculture. ; Environmental Social Sciences.
    Description / Table of Contents: Introduction -- Unconventional water resources as a response to global water scarcity and contribution to food, ecosystems, and sustainable development -- Rain enhancement through cloud seeding (Ali Abshaev, Hail Suppression Research Center, Nalchik, Russia) -- Fog water harvesting (Jamila Bargach, Dar Si Hmad Project, Sidi Ifni, Morocco) -- Micro-catchment rainwater harvesting (Theib Oweis, International Center for Agricultural Research in Dry Areas, ICARDA, Jordan) -- Offshore water (Mark Person, New Mexico Institute of Mining and Technology, USA) -- Onshore deep groundwater (Mark Person, New Mexico Institute of Mining and Technology, USA) -- Municipal wastewater (Birguy Lamizana, United Nations Environment Programme, UNEP, Nairobi, Kenya) -- Agricultural drainage water (J.D. Oster, University of California, Riverside, USA) -- Water transportation through icebergs towing (Nicholas Sloane, Resolve Marine Group, South Africa) -- Ballast water held in tanks and cargo holds of ships (Marlos De Souza, FAO) -- Desalinated water (Nikolay Voutchkov, Desalination Technologies Research Institute, Saline Water Conversion Corporation, SWCC, Jubail, Saudi Arabia) -- Governance, policies, and institutional and human capacity (Renée Martin-Nagle, A Ripple Effect PLC, Ebensburg, Pennsylvania, USA) -- Social and environmental tradeoffs (TBC) -- Economics and innovative financing mechanisms in a circular economy (Francesc Hernández-Sancho, University of Valencia, Spain; Edeltraud Guenther, UNU-FLORES) -- Way forward to harness the potential of unconventional water resources.
    Abstract: The world is faced with a growing number of complex and interconnected challenges. Water is among the top 5 global risks in terms of impacts, which would be far reaching beyond socio-economic challenges, impacting livelihoods and wellbeing of the people. As freshwater resources and population densities are unevenly distributed across the world, some regions and countries are already water scarce. Water scarcity is expected to intensify in regions like the Middle East and North Africa (MENA), which has 6% of the global population, but only 1% of the world’s freshwater resources. Climate change adds to this complexity as it is leading to rainfall uncertainty and extended droughts periods, mostly in arid areas. Increasing water scarcity is now recognized as a major cause of conflict, social unrest and migration and at the same time water is increasingly considered as an instrument for international cooperation to achieve sustainable development. Tapping and assessing sustainably every available option in water-scarce areas is needed as pressure continues to build on limited water resources. The stark fact is that conventional water provisioning approaches relying on snowfall, rainfall and river runoff are not enough to meet growing freshwater demand in water-scarce areas. Water-scarce countries need a radical re-think of water resource planning and management that includes the creative exploitation of a growing set of viable but unconventional water resources for food production, livelihoods, ecosystems, climate change adaption, and sustainable development. Unconventional water resources are generated as a by-product of specialized processes; need suitable pre-use treatment; require pertinent on-farm management when used for irrigation; or result from a special technology to collect/access water.
    Type of Medium: Online Resource
    Pages: XII, 309 p. 62 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030901462
    URL: https://doi.org/10.1007/978-3-030-90146-2
    DOI: 10.1007/978-3-030-90146-2
    DDC: 551.48
    Language: English
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    Nanowire-assisted Flow-through Electrode Enabling Electroporation Disinfection of Reclaimed Water (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Refuse and refuse disposal. ; Electrochemistry. ; Nanotechnology. ; Water. ; Environmental Engineering/Biotechnology. ; Waste Management/Waste Technology. ; Electrochemistry. ; Nanotechnology.
    Description / Table of Contents: Background -- Controlling Biological Risks in Reclaimed Water -- Preparation of Copper-oxide-nanowire-modified Foamed Copper Electrode -- The Disinfection Effect of Nanowire -- Effect of Cuprous Phosphide Nanowires -- Deposition of Polydopamine (PDA) Film on Nanowires -- Summary.
    Abstract: This Ph.D. book develops nanowire-assisted electroporation disinfection technology based on the flow-through porous electrode. The author presents pioneering results on theoretical modeling, experimental realization, and selected applications, showing the novel disinfection mechanism of electroporation guarantees an exceedingly low level of energy consumption. In this regard, three classes of novel dynamic behavior are investigated: (i) The developed nanowire-assisted flow-through electroporation disinfection technology enables great microbial disinfection performance with extremely low voltage (1V), which significantly reduce the formation potential of harmful disinfection by-products during the treatment process. (ii) The nanowire-assisted flow-through electroporation disinfection technology ensures no reactivation/regrowth of inactivated bacteria and meanwhile promotes the gradual death of damaged bacteria during the storage process. (iii) The application of high-frequency AC power supply (106 Hz) ensures the high microbial disinfection efficiency while suppressing the occurrence of electrochemical reactions and extending the electrode lifetime effectively.
    Type of Medium: Online Resource
    Pages: XIX, 143 p. 99 illus., 79 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819945023
    Series Statement: Springer Theses, Recognizing Outstanding Ph.D. Research,
    URL: https://doi.org/10.1007/978-981-99-4502-3
    DOI: 10.1007/978-981-99-4502-3
    DDC: 551.48
    Language: English
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    Nano-biotechnology for Waste Water Treatment : Theory and Practices (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Refuse and refuse disposal. ; Pollution. ; Environment. ; Environmental chemistry. ; Water. ; Waste Management/Waste Technology. ; Pollution. ; Environmental Sciences. ; Environmental Chemistry.
    Description / Table of Contents: Principles and potentials of nano-biotechnology -- Application of nano-biotechnology in municipal and industrial wastewater: An Overview -- Application of plant-based nanoparticles in wastewater decontamination -- Microbial synthesis of nanoparticles for waste water remediation -- Nano-materials for the Removal of Inorganic Contaminants from Industrial Wastewater.
    Abstract: This book embodies the potentials of nanobiotechnology-based water treatment techniques to provide a solid understanding of the subjects. Starting with a refresher of the basic conventional technologies which are now been integrated with nanomaterials for an efficient, viable, and eco-friendly treatment of contaminated water. The book covers various physical, chemical, and hybrid methods of nanobiomaterial synthesis and their fabrication for characterizing existing techniques. The book gives special attention to those nanotechnology-based approaches that promise easier, faster, and cheaper processes in contaminants monitoring and their treatment. Several case studies explain in an easy to understand format how employing nanobiomaterials as an indicator and analytical tool will enable students to learn about cleaning up the environment.
    Type of Medium: Online Resource
    Pages: VII, 397 p. 62 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031008122
    Series Statement: Water Science and Technology Library, 111
    URL: https://doi.org/10.1007/978-3-031-00812-2
    DOI: 10.1007/978-3-031-00812-2
    DDC: 551.48
    Language: English
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    Industrial Wastewater Treatment : Emerging Technologies for Sustainability (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Refuse and refuse disposal. ; Environmental management. ; Environmental chemistry. ; Biotechnology. ; Water. ; Waste Management/Waste Technology. ; Environmental Management. ; Environmental Chemistry. ; Biotechnology.
    Description / Table of Contents: Recent Developments in Membrane Filtration for Wastewater Treatment -- Ultrafiltration membrane water treatment system: An overview -- Ultrafiltration Integrated Photocatalytic Membrane Systems in Water and Wastewater Treatment: An Overview -- Application of electrospun polymeric nanofibrous membranes for water treatment -- Biosorbents in industrial wastewater treatment -- Nanoparticles in industrial wastewater treatment: An overview.
    Abstract: This book provides an overview of recent advances in technologies for water treatment processes, such as green technology, nano-adsorbents, photocatalysts, advanced oxidation, membranes separation and sustainable technologies. Advances in membrane technology and fabrication process is presented in detail. Latest approaches like microbial treatment, electro chemical and solar energy-based treatment techniques were presented. Also, the use of sustainable and energy efficient approaches were discussed. The book presents the negative impact of inorganic and organic pollutants on the natural environment and human health. It describes and discussing the advanced membrane technologies, novel green adsorbents, microbial treatment techniques, electro chemical and solar based removal techniques It also compares the most effective methods of removing toxic contaminants from water solutions with the use of sustainable and energy efficient approaches It also presents the life cycle assessment of emerging technologies in industrial wastewater treatment and desalination as well as presents the benchmarking of energy efficiency during treatment process.
    Type of Medium: Online Resource
    Pages: VIII, 475 p. 97 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030982027
    Series Statement: Water Science and Technology Library, 106
    URL: https://doi.org/10.1007/978-3-030-98202-7
    DOI: 10.1007/978-3-030-98202-7
    DDC: 551.48
    Language: English
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    Hydro-Meteorological Extremes and Disasters (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Environment. ; Sustainability. ; Refuse and refuse disposal. ; Water. ; Environmental Sciences. ; Sustainability. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter 1. Hydro-meteorological Extremes and Disasters: Integrated Risk, Remediation and Sustainability -- Chapter 2. Public Policy in Environment and Sustainability Strategies: Global & National Scenario -- Chapter 3. Title: Climate Finance at International and National level: Needs, Drivers and Sources -- Chapter 4. ECONOMIC IMPACTS OF HYDROCLIMATIC EXTREMES AND DISASTERS IN INDIA -- Chapter 5. Remote Sensing Applications in Drought Monitoring and Prediction -- Chapter 6. Disaster Early Warning Communication Systems -- Chapter 7. Spatial Data Infrastructure for suitable land identification for government projects -- Chapter 8. Role of Stable Isotopes in climate study - a multi-archive approach focusing on Holocene to Anthropocene records -- Chapter 9. Integration of Climate Model & Hydrology Model-Tools, Bias-Correction, Downscaling, & Future Focus -- Chapter 10. Analysis of Precipitation Extremes at the Intra-Seasonal Scale using a Regional Climate Model -- Chapter 11. Geospatial Big Data and its Applications -- Chapter 12. Quantitative Assessment of Impact of Climate Change on Crop Yield over Sikkim and Central Region of India -- Chapter 13. Understanding of future water challenges in a river basin under ensemble of CORDEX simulated projections -- Chapter 14. Drought as a disaster and its characterization over Central India -- Chapter 15. The Implications of Climate Change on Water Resources of Rajasthan -- Chapter 16. Thar Desert of India: Application of Geospatial Technology for Extreme Weather Events -- Chapter 17. Addressing Hydro-climatic Risks through Sectoral Planning: A case of National Agriculture Disaster Management Plan (NADMP) -- Chapter 18. India’s Health Adaptation Plan: Strategic Tool for Minimizing Disaster Related Losses and Damage.
    Abstract: The edited book provides both fundamentals as well as key factors of climate change, extreme events and disaster risk management. It systematically describes the integrated risk of various hydro-meteorological extreme events. The book brings together broad range of topics including basic concepts, exposure, risk, resilience and vulnerability. In addition, it also analysis the impact of various disaster events on bio-diversity, local communities, ecosystem and agricultural food production. The motive is to define remediation strategies in the fields of resilient infrastructures, communication strategies and immediate public participation. The book is presented in four parts, where part 1 familiarizes with fundamentals of hydro-meteorological based disasters; Part 2 focuses on risk and vulnerability analysis; Part 3 focuses on risk remediation options; and part 4 suggests the role of sustainable planning framework on disaster risk management. This volume is of interest and use to professionals and researchers working in climate change, atmospheric sciences and disaster management.
    Type of Medium: Online Resource
    Pages: XIV, 328 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811907258
    Series Statement: Disaster Resilience and Green Growth,
    URL: https://doi.org/10.1007/978-981-19-0725-8
    DOI: 10.1007/978-981-19-0725-8
    DDC: 551.48
    Language: English
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    Inorganic Materials for Energy, Medicine and Environmental Remediation (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Waste Management/Waste Technology.
    Description / Table of Contents: Chapter 1 Localized surface plasmon resonance in colloidal copper sulphide (Cu2-xS, x=0≤x^nts in wastewater -- Chapter 9 Removal of persistent organic pollutants using redox active metal oxide nanocatalysts via advanced oxidation process -- Chapter 10 Metal-based particles as a catalyst for Proton exchange membrane fuel cells.
    Abstract: This book presents concepts, methods and applications of inorganic nanomaterials for energy applications such as fuel cells and batteries, for environmental applications such as water purification, and for medicinal applications such as cancer treatments. The founding father of nanotechnology, Eric Drexler, always communicated a unique vision in exploring new materials and creating advancements in molecular nanotechnology. He emphasized the potential advantages of smaller size, higher efficiency and less needed resources for applications in energy, environment and medicine. A higher surface to volume ratio of inorganic nanomaterials is a key property.
    Type of Medium: Online Resource
    Pages: XV, 258 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030798994
    Series Statement: Environmental Chemistry for a Sustainable World, 69
    URL: https://doi.org/10.1007/978-3-030-79899-4
    DOI: 10.1007/978-3-030-79899-4
    DDC: 551.48
    Language: English
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