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  • Books  (49)
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  • 2020-2024  (49)
  • 1955-1959
  • 2021  (49)
  • 1956
  • 551.48  (25)
  • 571.96  (24)
  • 1
    Online Resource
    Online Resource
    Immunodiagnostic Technologies from Laboratory to Point-Of-Care Testing (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Immunology. ; Biotechnology. ; Clinical biochemistry. ; Medicine Research. ; Biology Research. ; Immunology. ; Biotechnology. ; Medical Biochemistry. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Timeline of the evolution of immunodiagnostics -- Chapter 2. Receptors in immunodiagnostics: Antibody and their derivatives -- Chapter 3. Engineering antibodies for biointerfacing -- Chapter 4. Alternative analyte-binding compounds for immunosensor applications -- Chapter 5. Principles and applications of immunodiagnostics using radioisotopes as tracers -- Chapter 6. Advancements and application of optical detection system in deleveopment of optical sensors -- Chapter 7. Miniaturized technologies in immunodiagnostics -- Chapter 8. Prospects of Point of care diagnostics for medical applications -- Chapter 9. Potential and advancements in namomaterial for diagnostic applications -- Chapter 10. Photoelectrochemical immunosensor in clinical diagnosis -- Chapter 11. Mutiplexing in immunodiagnosis -- Chapter 12. Biosensors for clinical samples: Considerastion and approaches -- Chapter 13. Application of immunodiagnostics in diagnosis of animal diseases -- Chapter 14. Changing trends in medical diagnosis and health monitoring with advancements in immunosensing technologies -- Chapter 15. Future perspective of immunodiagnostics in clinical applications -- Chapter 16. Commercial aspects of immunoasensors and immuoassays: Short-cominmg and future aspects.
    Abstract: This book presents the timeline of immunodiagnostics evolution, including advancements in immunological/nucleic acid probes, assay design, labelling techniques, and devices for signal transduction and acquisition. In the past few years, enzyme and nanocatalyst-based immune assays have undergone numerous modifications to enhance their sensitivity and potential for automation. Further, to reduce production costs and the use of laboratory animals, engineering small antibodies and nucleic acid probes (aptamers) has become increasingly popular in the development of novel and powerful bioassays. In light of the notable advancements in immunodiagnostics, this book highlights the combined efforts of clinicians, biotechnologists, material scientists, nanotechnologists and basic scientists in a coherent and highly structured way. The book takes readers on the journey of immunodiagnostic technologies, from their introduction to the present.
    Type of Medium: Online Resource
    Pages: VIII, 245 p. 64 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811558238
    URL: https://doi.org/10.1007/978-981-15-5823-8
    DOI: 10.1007/978-981-15-5823-8
    DDC: 571.96
    Language: English
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  • 2
    Online Resource
    Online Resource
    Primary and Secondary Immunodeficiency : A Case-Based Guide to Evaluation and Management (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Rheumatology. ; Diseases. ; Hematology. ; Oncology. ; Primary care (Medicine). ; Immunology. ; Rheumatology. ; Diseases. ; Hematology. ; Oncology. ; Primary Care Medicine.
    Description / Table of Contents: Chapter 1. Overview of Immunodeficiency -- Part I. B-Lymphocyte Immunodeficiency -- Chapter 2. Common Variable Immunodeficiency, Hypogammaglobulinemia, and Specific Antibody Deficiency -- Chapter 3. Agammaglobulinemia -- Chapter 4. Class Switch Defects -- Chapter 5. Transient Immunodeficiency of Infancy -- Chapter 6. Selective Isotype Immunodeficiency -- Chapter 7. Common Variable Immunodeficiency Disorders-like Disorders -- Part II. T-Cell Immunodeficiency -- Chapter 8. Severe Combined Immunodeficiency -- Chapter 9. Idiopathic CD4 Lymphopenia -- Chapter 10. Hyper IgE Syndrome -- Chapter 11. Genetic Syndromes with Associated Immunodeficiencies -- Part III. Immune Dysregulation Syndromes -- Chapter 12. Autoimmune Lymphoproliferative Syndrome -- Chapter 13. Auto-inflammatory Syndromes -- Chapter 14. Immune Dysregulation Leading to Autoimmunity -- Chapter 15. Dendritic Cells in Primary Immunodeficiency -- Part IV. Innate Immune Defects -- Chapter 16. Congenital Neutropenia and Migration Defects -- Chapter 17. Chronic Granulomatous Disease -- Chapter 18. Primary Immunodeficiencies of Complement -- Chapter 19. Natural Killer Cell Defects -- Chapter 20. Mucocutaneous Candidiasis -- Part V. Secondary Immunodeficiency -- Chapter 21. Immunodeficiency Secondary to Malignancies and Biologics -- Chapter 22. Immunodeficiency Secondary to Prematurity, Pregnancy, and Aging -- Chapter 23. Vaccinations in Primary and Secondary Immunodeficiencies Including Asplenia.
    Abstract: This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.
    Type of Medium: Online Resource
    Pages: XI, 417 p. 34 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571573
    URL: https://doi.org/10.1007/978-3-030-57157-3
    DOI: 10.1007/978-3-030-57157-3
    DDC: 571.96
    Language: English
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  • 3
    Online Resource
    Online Resource
    Lung Inflammation in Health and Disease, Volume II (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Human physiology. ; Medicine Research. ; Biology Research. ; Respiratory organs Diseases. ; Immunology. ; Human Physiology. ; Biomedical Research. ; Pneumology.
    Description / Table of Contents: 1. Can GPCRs be targeted to control inflammation in asthma? -- 2. Cellular and molecular processes in pulmonary hypertension -- 3. INFLAMMATORY PATHWAYS IN SARCOIDOSIS -- 4. Innate Immune Responses and Pulmonary Diseases -- 5. Interstitial Lung Disease associated with Connective Tissue Diseases -- 6. Molecular mechanisms of vascular damage during lung injury -- 7. Neurotrophin Regulation and Signaling in Airway Smooth Muscle -- 8. Novel Thoracic MRI approaches for the assessment of pulmonary physiology and inflammation -- 9. Overview on Interactive Role of Inflammation, Reactive Oxygen Species and Calcium signaling in Asthma, COPD and Pulmonary Hypertension -- 10. Protein S-palmitoylation and lung diseases -- 11. Redox role of ROS and inflammation in pulmonary diseases -- 12. Semaphorin3E/PlexinD1 axis in asthma: what we know so far -- 13. Serine protease inhibitors to treat lung inflammatory diseases -- 14. Sex and Gender Differences in Lung Disease -- 15. Sex hormones and lung inflammation -- 16. Synopsis of Clinical Acute Respiratory Distress Syndrome (ARDS).
    Abstract: Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
    Type of Medium: Online Resource
    Pages: XVI, 384 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030687489
    Series Statement: Advances in Experimental Medicine and Biology, 1304
    URL: https://doi.org/10.1007/978-3-030-68748-9
    DOI: 10.1007/978-3-030-68748-9
    DDC: 571.96
    Language: English
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  • 4
    Online Resource
    Online Resource
    Neurocognitive Complications of HIV-Infection : Neuropathogenesis to Implications for Clinical Practice (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Neurosciences. ; Virology. ; Immunology. ; Neuroscience. ; Virology.
    Description / Table of Contents: I. Neuropathogenesis and Biomarkers -- New Potential Axes of HIV Neuropathogenesis with Relevance to Biomarkers and Treatment -- Neurocognitive Impairment and Associated Genetic Aspects in HIV Infection -- Inflammatory Mechanisms and Cascades Contributing to Neurocognitive Impairment in HIV/AIDS -- Neuroimaging Advances in Diagnosis and Differentiation of HIV, Comorbidities, and Aging in the cART Era -- II. Neurocognitive Impairments in Low-, Middle- and High-Income Countries – Incidence / Prevalence and Contexts -- Neurocognitive Complications of Pediatric HIV Infections -- Neurocognitive Complications of HIV Infection in Women: Insights from the WIHS Cohort -- Cultural Neuropsychology Considerations in the Diagnosis of HIV- Associated Neurocognitive Disorders -- Neurocognitive Complications of HIV Infection in Low-Income Countries -- Deep Phenotyping of HIV Neurocognitive Complications Among Individuals Residing in High-Income Countries -- Reliably Measuring Cognitive Change in the Era of Chronic HIV Infection and Chronic HIV-Associated Neurocognitive Disorders -- III. Comorbidities and Complications -- Geriatric Syndromes in People Living with HIV Associated with Ageing and Increasing Comorbidities: Implications for Neurocognitive Complications of HIV Infection -- Conceptualizing and Assessing Everyday Functioning in the Context of HIV-Associated Neurocognitive Disorders -- Neuropsychiatric Disorders, Emotional Disturbances, and Their Associations with HIV-Associated Neurocognitive Disorder -- Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders -- HIV-Associated Neurocognitive Disorder (HAND): Relative Risk Factors -- IV. Screening, Interventions and Clinical Management -- Screening for HIV-Associated Neurocognitive Disorders: Sensitivity and Specificity -- Behavioral and Physical Activity Interventions for HAND -- Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging Literature -- Clinical Treatment Options and Randomized Clinical Trials for Neurocognitive Complications of HIV Infection: Combination Antiretroviral Therapy, Central Nervous System Penetration Effectiveness, and Adjuvants.
    Abstract: This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis. The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: XVII, 545 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030807597
    Series Statement: Current Topics in Behavioral Neurosciences, 50
    URL: https://doi.org/10.1007/978-3-030-80759-7
    DOI: 10.1007/978-3-030-80759-7
    DDC: 571.96
    Language: English
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  • 5
    Online Resource
    Online Resource
    Antibody Glycosylation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Pharmacology. ; Biochemical markers. ; Analytical chemistry. ; Biotechnology. ; Immunology. ; Pharmacology. ; Biomarkers. ; Bioanalytical Chemistry. ; Biotechnology.
    Description / Table of Contents: Microheterogeneity of antibody molecules -- Part I: Analytical Methods -- Lectin and LC based methods for immunoglobulin (G) glycosylation analysis -- Mass spectrometry-based methods for immunoglobulin G N-glycosylation analysis -- CE based methods for Ig(G) glycosylation analysis -- Automation of Ig glycosylation analysis -- Bioinformatics in immunoglobulin glycosylation analysis -- Part II: Biosynthesis & Regulation -- N-glycan biosynthesis: Basic principles and factors affecting its outcome -- Genetic regulation of immunoglobulin G glycosylation -- Epigenetics of immunoglobulin G glycosylation -- IgG changes in aging and other inflammatory conditions -- Estrogen-driven changes in immunoglobulin G Fc glycosylation -- Part III: Effector Functions & Diseases -- Sweet rules – linking glycosylation to antibody function -- Immunoglobulin G glycosylation in diseases -- Immunoglobulin A glycosylation and its role in diseases -- Part IV: Applications -- Importance and monitoring of therapeutic immunoglobulin G glycosylation -- Glycosylation of plant-produced immunoglobulins -- The rapidly expanding nexus of immunoglobulin G N-glycomics, suboptimal health status, and precision medicine -- Glycosylation of antigen-specific antibodies - Perspectives on immunoglobulin G glycosylation in vaccination and immunotherapy.
    Abstract: This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 591 p. 66 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030769123
    Series Statement: Experientia Supplementum, 112
    URL: https://doi.org/10.1007/978-3-030-76912-3
    DOI: 10.1007/978-3-030-76912-3
    DDC: 571.96
    Language: English
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  • 6
    Online Resource
    Online Resource
    Inflammation and Epilepsy: New Vistas (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Neurology . ; Neurosciences. ; Diseases. ; Pharmacology. ; Immunology. ; Neurology. ; Neuroscience. ; Diseases. ; Pharmacology.
    Description / Table of Contents: Pro and Anti-Inflammatory Neurovascular Processes in Epilepsy: A Fragile and Dynamic Equilibrium -- Emerging Molecular Mechanisms of Neuroinflammation in Seizure Disorders -- Glial Mechanisms of Inflammation during Seizures -- Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction and Epilepsy -- Blood T cells and Cytokine Levels during Interictal-Ictal Transitions -- Autoantibodies, Encephalopathies and Epilepsy -- Tau Protein in Drug-Resistant Epilepsy and Cognitive Decline -- Ketogenic Diet, Inflammation and Epilepsy -- Role of Regulatory T cells in Epilepsy -- Inflammation at the Neurovascular Unit in Post-Traumatic Epilepsy.
    Abstract: This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
    Type of Medium: Online Resource
    Pages: VIII, 237 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030674038
    Series Statement: Progress in Inflammation Research, 88
    URL: https://doi.org/10.1007/978-3-030-67403-8
    DOI: 10.1007/978-3-030-67403-8
    DDC: 571.96
    Language: English
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  • 7
    Online Resource
    Online Resource
    Amino Acids in Nutrition and Health : Amino Acids in the Nutrition of Companion, Zoo and Farm Animals (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Prelims -- One-carbon metabolism and development of the conceptus during pregnancy: Lessons from studies with sheep and pigs -- Cell-specific expression of enzymes for serine biosynthesis and glutaminolysis in farm animals -- Amino acids in beef cattle nutrition and production (author to be identified) -- Amino acid nutrition and reproductive performance in ruminants -- Amino acids in the nutrition and production of sheep and goats -- Amino acids in swine nutrition and production -- Amino acid nutrition and metabolism in chickens -- Nutrition and functions of amino acids in fish -- Nutrition and functions of amino acids in aquatic crustaceans -- Amino acids in dog nutrition and health -- Amino acids in the nutrition, metabolism, and health of domestic cats -- Amino acid nutrition for optimum growth, development, reproduction, and health of zoo animals.
    Abstract: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in companion (dogs and cats), zoo (carnivores, herbivores, and omnivores), and farm (including cattle, pigs, sheep, goats, chickens, fish, and crustaceans) animals. It enables readers to understand the crucial roles of amino acids and their metabolites in the growth, development, health, and metabolic diseases of these animals. Readers will learn from well-written chapters that amino acids are not only the building blocks of protein but are also signaling molecules and key regulators of gene expression and whole body homeostasis in companion, domestic, aquatic, and captive animals. The book also provides new and useful information on the optimum requirements of the animals for dietary amino acids. This knowledge will guide nutritional practices and daily management to improve the health and survival of all species and to enhance the productivity of livestock, poultry, and aquaculture enterprises worldwide to produce high-quality protein for human consumption. Editor of this volume is an internationally recognized expert in the biochemistry, nutrition and physiology of amino acids. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals and pet owners, as well as undergraduate and graduate students in animal science, aquaculture, zoology, wildlife, veterinary medicine, biology, biochemistry, food science, nutrition, pharmacology, physiology, toxicology, and other related disciplines. In addition, all chapters provide general and specific references to amino acid nutrition and metabolism for researchers and practitioners in animal agriculture, aquaculture, zoos, biomedicine, and plant science, and for government policy makers. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VI, 256 p. 36 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030544621
    Series Statement: Advances in Experimental Medicine and Biology, 1285
    URL: https://doi.org/10.1007/978-3-030-54462-1
    DOI: 10.1007/978-3-030-54462-1
    DDC: 571.96
    Language: English
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  • 8
    Online Resource
    Online Resource
    Amino Acids in Nutrition and Health : Amino Acids in Gene Expression, Metabolic Regulation, and Exercising Performance (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Chapter 1: Regulation of Gene Expression by Amino Acids in Animal Cells -- Chapter 2: Amino acids in cell signaling: regulation and function -- Chapter 3: Amino Acids in Endoplasmic Reticulum Stress and Redox Signaling -- Chapter 4: Amino Acids in Autophagy: Regulation and Function -- Chapter 5: Oxidation of Energy Substrates in Tissues of Fish: Metabolic Significance and Implications for Gene Expression and Carcinogenesis -- Chapter 6: Arginine, Agmatine and Polyamines: Key Regulators of Conceptus Development in Mammals -- Chapter 7: Interorgan Metabolism of Glutamate and Glutamine in Poultry -- Chapter 8: Interorgan Metabolism of Amino Acids in Health and Disease -- Chapter 9: Amino Acids and Their Metabolites for Improving Human Exercising Performance -- Chapter 10: Role of L-Arginine in Nitric Oxide Synthesis and Health in Humans -- Chapter 11: Composition of Amino Acids in Foodstuffs for Humans and Animals -- Chapter 12: Dietary Intakes of Amino Acids and Other Nutrients by Adult Humans.
    Abstract: This book explains about amino acids (AAs) which are not only building blocks of protein, but are also signaling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular-weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds, and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole-body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health, and well-being of individuals.
    Type of Medium: Online Resource
    Pages: VI, 227 p. 34 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030741808
    Series Statement: Advances in Experimental Medicine and Biology, 1332
    URL: https://doi.org/10.1007/978-3-030-74180-8
    DOI: 10.1007/978-3-030-74180-8
    DDC: 571.96
    Language: English
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  • 9
    Online Resource
    Online Resource
    Western Blotting for the Non-Expert (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Immunology. ; Biomedical Research. ; Biotechnology.
    Description / Table of Contents: Western blotting: How it began -- 2. Basics of Western Blotting -- 3.Basic Calculations in Western Blotting -- 4.Choosing The Right Antibody For Western Blotting -- 5. Sample Preparation -- 6. Blocking membranes at places that do not have transferred proteins -- 7. A Basic Method for Western Blotting -- 8. Trouble Shooting Western Blotting -- 9. Using Biotin to demonstrate western and dot blotting in University Practical Classes- A Guide To Instructors -- 10. Nitrocellulose Membrane Art -- 11. The Use Of A Harmless Invisible Ink To Send Secret Messages On Nitrocellulose Membranes And As A Substitute For The Harmful Radioactive Ink Used As A Marker In ECL Membrane Assays -- 12. Fingerprinting On Nitrocellulose And Polyvinylidene Difluoride Membrane -- 13. Spectrometric Determination Of Protein For Electrophoresis -- 14. Concentrating Proteins For Western Blotting -- 15. Dissolving Proteins Using Lysis Buffer -- 16. Blotting And Detecting Glycosaminoglycans -- 17. Passive Blotting From Tissue Slices -- 18. Localizing Proteins by Tissue Printing -- 19. Ultrasound Blotting -- 20. Obtaining Several Blots From A Single SDS-PAGE Gel By Passive Transfer -- 21. Diffusion Blotting From SDS-PAGE Gels Supported By Solid Plastic -- 22. Dot-Immunobinding -- 23. Simultaneous Immunoblotting Analysis With Activity Gel Electrophoresis -- 24. Protein Blotting By Centrifugation -- 25. Blotting And Immunostaining Of Multiple Antigenic Peptides -- 26. High Molecular Weight Protein Blotting Using Agarose Gel Electrophoresis -- 27. Cetyltrimethylammonium bromide PAGE And Eastern Blotting -- 28. Purification Of Autoantibodies Bound To An Autoantigen Immobilized On A Membrane Strip -- 29. Miniaturized Blotting -- 30. Affinity Immunoblotting -- 31. Transferring Coomassie Blue Stained Proteins from Polyacrylamide Gels To Transparencies -- 32. Protein Transfer From Immobilized pH Gradient Gels -- 33. SDS PAGE To Immunoblotting In Sixty Minutes -- 34. Western Blot Analysis Of Protein-DNA Complexes Formed DuringGel Shift Experiments -- 35. Electrophoretic Transfer Of High And Low Molecular Weight Proteins To Membranes Using Heat -- 36. Grid-immunoblotting -- 37. Far-western Blotting -- 38. Native Electrophoresis And Western Blot Analysis -- 39. Efficient Electroblotting Of Low Molecular Weight Protein After Staining With Coomassie -- 40. Avoiding Non-specific Binding Of Secondary Antibodies In Immunoblotting By Double-blotting -- 41.A Brief Introduction To Other Protein Blotting Methods -- 42. Quantitative Computerized Western Blotting In Detail -- 43. Common Problems In Electrophoresis.
    Abstract: This book fills the need for a simplified text covering western blotting protocols aimed not just at high school and college students, but the researcher with little to no experience in these techniques. It provides the principles, basic methodology, and tips and tricks to avoiding the common pitfalls of western blotting. The book also introduces simple protocols that can transform western blotting into a fun method, such as sending secret messages on membranes or using nitrocellulose membrane as a canvas for art. In addition to the techniques, this book also covers the history of western blotting, which originated from the development of the blotting of DNA. It then delves into the importance of protein blotting, brought to the fore by the fact that the procedure has been evolving constantly since its inception in 1979, and the fact that the scientific community is faced with a multitude of ways and means of transferring proteins to membranes.
    Type of Medium: Online Resource
    Pages: XXIII, 467 p. 611 illus., 170 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030706845
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-70684-5
    DOI: 10.1007/978-3-030-70684-5
    DDC: 571.96
    Language: English
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  • 10
    Online Resource
    Online Resource
    Immunotherapy – A Novel Facet of Modern Therapeutics (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Immunology. ; Human physiology. ; Cancer. ; Pharmaceutical chemistry. ; Pharmacology. ; Immunology. ; Human Physiology. ; Cancer Biology. ; Pharmaceutics. ; Pharmacology.
    Description / Table of Contents: Chapter 1. Immunotherapy – a Concept -- Chapter 2. Immunotherapy in Cancer - Immune Checkpoint Inhibitors; changing Oncology treatment paradigm -- Chapter 3. Vaccines as Immunotherapy -- Chapter 4. Immunotherapy for Autoimmune Diseases -- Chapter 5. Immunotherapy in neurodegenerative disorders -- Chapter 6. Companion diagnostics and clinical biomarkers for immunotherapy -- Chapter 7. Novel Drug Delivery Systems for Immunotherapeutics -- Chapter 8. Discovery, Screening Methods, Design Considerations and Scale-up aspects of Immunotherapeutic Drugs -- Chapter 9. Pharmacokinetics, Pharmacodynamics, and Toxicology aspects of Immunotherapeutics -- Chapter 10. Regulatory Affairs and Intellectual Property Rights in Immunotherapeutics -- Chapter 11. Future immunotherapy challenges and perspectives. .
    Abstract: This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs. It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance. Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies. .
    Type of Medium: Online Resource
    Pages: VIII, 262 p. 15 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811590382
    URL: https://doi.org/10.1007/978-981-15-9038-2
    DOI: 10.1007/978-981-15-9038-2
    DDC: 571.96
    Language: English
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  • 11
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    Online Resource
    Medical and Biomedical Updates (2021)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Human physiology. ; Respiratory organs. ; Physiology. ; Immunology. ; Human Physiology. ; Respiratory Physiology.
    Description / Table of Contents: Role of IP3 Receptors in Shaping the Carotid Chemoreceptor Response to Hypoxia but not to Hypercapnia in the Rat Carotid Body: An Evidence Review -- The Role of Hyperbaric Oxygen Treatment for COVID-19: A Review -- Primary Immunodeficiencies - Diseases of Children and Adults: A Review -- Pneumococcal Vaccine in Adult Asthma Patients -- Immunoglobulin G Deficiency in Children with Recurrent Respiratory Infections with and without History of Allergy -- Pruritus Characteristics in Severe Atopic Dermatitis in Adult Patients -- Pathophysiological Responses to a Record-Breaking Multi-Hour Underwater Endurance Performance: A Case Study -- Respiratory Muscle Strength and Ventilatory Function Outcome: Differences between Trained Athletes and Healthy Untrained Persons -- Uroflowmetry and Altitude Hypoxia: A Report from Healthy Italian Trekkers and Nepali Porters during Himalayan Expedition -- Effects of Intraligamentary Injection of Osteogenic-Induced Gingival Fibroblasts on Cementum Thickness in the Dog Model of Tooth Root Resorption -- In-Silico Evaluation of Treatment of Periprosthetic Fractures in Elderly Patients after Hip Arthroplasty -- Appraisal of burden of caregivers to chronically rehabilitated patients with spinal cord injuries in a tertiary neurological center in Nepal.
    Abstract: This book integrates topics in basic research and clinical medicine as well as molecular and cell biology. It presents innovative advances in the field of immunodeficiency syndromes and viral/bacterial respiratory infections, including a novel hyperbaric oxygen treatment for COVID-19. A comprehensive insight is offered into the unresolved molecular pathways in chemosensing that plays a vital role in detecting insufficient tissue oxygenation, as well as in sporting accomplishments. Other articles address cardiorespiratory and humoral responses to hypoxia, the function of cementum in the repair and regeneration of teeth, and periprosthetic fractures following hip arthroplasty in the elderly. The issue of the overwhelming burdens on caregivers to spinal injury patients, damaging both health and psychosocial status, is addressed. The book promotes translation of scientific advances to the general medical practice. It will be a valuable reference for clinical healthcare professionals and researchers interested in innovative practices to improve the prevention, diagnosis, and management of diseases.
    Type of Medium: Online Resource
    Pages: VI, 131 p. 20 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030672164
    Series Statement: Clinical and Experimental Biomedicine, 1289
    URL: https://doi.org/10.1007/978-3-030-67216-4
    DOI: 10.1007/978-3-030-67216-4
    DDC: 571.96
    Language: English
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  • 12
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    Online Resource
    Mathematical, Computational and Experimental T Cell Immunology (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Bioinformatics. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Cytokine receptor signaling and CD4/CD8 lineage choice during T cell development in the thymus -- An agent-based model of T helper cell fate decisions in the thymus -- Modelling naive T cell homeostasis -- Mechanistic models of CD4 T cell homeostasis and reconstitution in health and disease -- Section 1MODELING THE DYNAMICS OF CD4+ T CELLS IN HIV- 1 INFECTION -- Modelling the response to Interleukin-7 therapy in HIV-infected patients -- Modeling immunopathology during persistent viral infections -- Delay in differentiation may suggest division of labour in models for CD8+ T cell differentiation -- Inferring differentiation order in adaptive immune responses from population level data -- Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes -- The public face and private lives of T cell receptor repertoires -- Population dynamics of immune repertoires -- Mathematical Modelling of T cell activation -- Agent-based model of heterogeneous T cell activation in vitro -- CTLA-4 mediated ligand trans-endocytosis: a stochastic model -- Automated gating and dimension reduction of high-dimensional cytometry data -- Index.
    Abstract: The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modelled. We aim in the proposed book to emphasise the role that mathematical (or computational) modelling has already played in Immunology. Each chapter will provide an example of the contribution of mathematics to T cell immunology under one of the following four headings: i) Generation of hypotheses, ii) Quantification of immunological processes, iii) Definition of observables to measure given an experimental objective, iv) reconciling disparate (or even conflicting) experimental results. .
    Type of Medium: Online Resource
    Pages: X, 298 p. 74 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030572044
    URL: https://doi.org/10.1007/978-3-030-57204-4
    DOI: 10.1007/978-3-030-57204-4
    DDC: 571.96
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  • 13
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    Online Resource
    Lung Inflammation in Health and Disease, Volume I (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Human physiology. ; Medicine Research. ; Biology Research. ; Respiratory organs Diseases. ; Immunology. ; Human Physiology. ; Biomedical Research. ; Pneumology.
    Description / Table of Contents: 1. Potential role of mast cells in regulating corticosteroid insensitivity in severe asthma -- 2. Galectin-3 Promotes ROS, Inflammation and Vascular Fibrosis in Pulmonary Arterial Hypertension -- 3. Anti-Inflammatory Effects of Statins in Lung Vascular Pathology: From Basic Science to Clinical Trials -- 4. Evolving Schema for Employing Network Biology Approaches to Understand Pulmonary Hypertension -- 5. Pulmonary Inflammation and KRAS Mutation in Lung Cancer -- 6. microRNA Targets for Asthma Therapy -- 7. Roles of genetic predisposition in the sex-bias of pulmonary pathophysiology, as a function of estrogens -- 8. Hypercapnic respiratory failure-driven skeletal muscle dysfunction: It is time for animal mod-els-based mechanistic research -- 9. Role of airway smooth muscle in inflammation related to asthma and COPD -- 10. Systemic Sclerosis and Pulmonary Disease -- 11. Innate Lymphoid Cells in airway inflammation -- 12. Sjogren’s Syndrome and pulmonary disease -- 13. Redox Regulation, Oxidative Stress and Inflammation in Group 3 Pulmonary Hypertension -- 14. Sex-Steroid Signaling in Lung Diseases and Inflammation -- 15. Cytokines, Chemokines and Inflammation in Pulmonary Arterial Hypertension -- 16. Interactive roles of CaMKII/Ryanodine Receptor Signaling and Inflammation in Lung Diseases -- 17. Reciprocal Correlations of Inflammatory and Calcium Signaling in Asthma Pathogenesis -- 18. Crosstalk between Lung and Extrapulmonary Organs in Infection and Inflammation -- 19. Inflammation in Pulmonary Arterial Hypertension -- 20. Lysophospholids in Lung Inflammatory Diseases.
    Abstract: Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung diseases are neither always effective, nor often condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases are not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung diseases, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, fellows, and students with new perspectives and concepts. The editor hopes this book will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
    Type of Medium: Online Resource
    Pages: XV, 409 p. 54 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030630461
    Series Statement: Advances in Experimental Medicine and Biology, 1303
    URL: https://doi.org/10.1007/978-3-030-63046-1
    DOI: 10.1007/978-3-030-63046-1
    DDC: 571.96
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  • 14
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    Online Resource
    Pathogenesis of Systemic Lupus Erythematosus : Insights from Translational Research (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Cytokines. ; Immunology. ; Biomedical Research. ; Cytokines and Growth Factors.
    Description / Table of Contents: Advances in translational science to identify new therapies for systemic lupus erythematosus -- Hallmark of systemic lupus erythematosus: Role of B Cell Hyperactivity. Fabien B Vincent, William A Figgett and Margaret L Hibbs -- B cell targeted therapies in systemic lupus erythematosus -- Type I Interferons and the perpetuation of a loss of tolerance -- Therapeutic Modulation of the Interferon Pathway in Systemic Lupus Erythematosus -- The concept of co-stimulatory blockade in SLE -- Cytokines: their role in amplifying SLE pathogenesis -- Intracellular targets in SLE -- Regulatory T cells in SLE -- Balancing strategies: GC and GILZ Axis.
    Abstract: The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.
    Type of Medium: Online Resource
    Pages: XXI, 178 p. 36 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851613
    URL: https://doi.org/10.1007/978-3-030-85161-3
    DOI: 10.1007/978-3-030-85161-3
    DDC: 571.96
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  • 15
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    Groundwater and Society : Applications of Geospatial Technology (2021)
    Cham :Springer International Publishing :
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    Keywords: Water. ; Hydrology. ; Geographic information systems. ; Sustainability. ; Environmental protection. ; Civil engineering. ; Water. ; Geographical Information System. ; Sustainability. ; Soil and Water Protection.
    Description / Table of Contents: Chapter 1. Introduction: Groundwater and Society: Applications of Geospatial Technology (Pravat Kumar Shit, Gouri Sankar Bhunia, Partha Pratim Adhikary, Ch. Jyotiprava Dash) -- Part I: Groundwater resources and societal development -- Chapter 2. Groundwater and Society in India: Challenging Issues and Adaptive Strategies (Subrata Jana) -- Chapter 3. Groundwater Research and Societal Development: Integration with Remote Sensing and Geographical Information System (Gouri Sankar Bhunia, Pravat Kumar Shit, Partha Pratim Adhikary and Debashish Sengupta) -- Chapter 4. Geospatial and Geophysical Approaches for Assessment of Groundwater Resources in an Alluvial Aquifer of India (Partha Pratim Adhikary, S.K.Dubey, Debashis Chakraborty, Ch. Jyotiprava Dash) -- Chapter 5. Groundwater and Space Technology: Issues and challenges (Gouri Sankar Bhunia, Pravat Kumar Shit, Harsha Das Gupta, Partha Pratim Adhikary) -- Part II: Groundwater availability, quality and pollution -- Chapter 6. Groundwater Quality through Multi-criteria based GIS Analysis: Village Level Assessment (Baisakhi Chakraborty, Sambhunath Roy, Gouri Sankar Bhunia, Debashish Sengupta, Pravat Kumar Shit) -- Chapter 7. GIS-based Fuzzy-AHP Approach for Assessment of Groundwater Potential Zones of an Urban Agglomeration (Suraj Kumar Mallick, Somnath Rudra) -- Chapter 8. Assessment of Groundwater Availability in Gumani River Basin, India using Geoinformatics and Analytical Hierarchy Process (Sadik Mahammad, Aznarul Islam) -- Chapter 9. Application of AHP for Groundwater Potential Zones Mapping in Plateau Fringe Terrain: Study from Western Province of West Bengal (Manas Karmakar, Monali Banerjee, Mrinal Mandal, Debasis Ghosh) -- Chapter 10. Performance of Frequency Ratio Approach for Mapping of Groundwater Prospect Areas in an Area of Mixed Topography (Subhas Garai, Pulakesh Das) -- Chapter 11. Artificial Neural Network for Identification of Groundwater Potential Zones in part of Hugli District, West Bengal, India (Chalantika Laha Salui and Shashank Yadav) -- Chapter 12. Multi-criteria Analysis for Groundwater Quality Assessment: A Study in Paschim Barddhaman District of West Bengal, India (Payel Das, Niladri Das) -- Chapter 13. Performance of WQI and HPI for Groundwater Quality Assessment: Study from Sangramgarh Colliery of West Burdwan District, West Bengal, India (Tanushree Paul, Manas Nath) -- Chapter 14. Assessment of Groundwater Quality interaction using One-decade Data: Case Study from a Hard Rock Area (S. Satheeshkumar, S. Venkateswaran, T. Maheshwari) -- Chapter 15. Fluoride Dynamics in Precambrian Hard Rock Terrain of North Singbhum Craton and Effect of Fluorosis on Human Health and Society (Biswajit Bera, Sumana Bhattacharjee, Meelan Chamling, Arijit Ghosh, Nairita Sengupta, Supriya Ghosh) -- Chapter 16. Coastal Aquifer Vulnerability for Saltwater Intrusion: A Case Study of Chennai Coast Using GALDIT Model and Geoinformatics (Debabrata Ghorai, Gouri Sankar Bhunia, Pravat Kumar Shit) -- Part III: Sustainable Groundwater resources management -- Chapter 17. Watershed Development Impact on Natural Resources: Groundwater and Surface Water Utilization (Partha Pratim Adhikary, M. Madhu, P. Jakhar, B.S. Naik, H.C. Hombegowda, D. Barman, G.B. Naik, Ch. J. Dash) -- Chapter 18. Long-term Groundwater Behaviour over an Agriculturally Developed State of North-West India: Trend and Impact on Agriculture (Omvir Singh, Amrita Kasana, Pankaj Bhardwaj) -- Chapter 19. Spatial Appraisals of Groundwater Recharge Potential Zone Identification using Remote Sensing and GIS (Gouri Sankar Bhunia, Pranab Kumar Maity, Pravat Kumar Shit) -- Chapter 20. Spatial Mapping of Groundwater Depth to Prioritize the Areas under Water Stress in Rayalaseema Region of Andhra Pradesh, India (Ch. Jyotiprava Dash, PP Adhikary, Uday Mandal) -- Chapter 21. Exploring Vulnerability of Groundwater using AHP and GIS Techniques: A Study in Cooch Behar District, West Bengal, India (Dipankar Saha, Debasish Talukdar, Ujjal Senapati, Tapan Kumar Das) -- Chapter 22. Applicability of Geospatial Technology, Weight of Evidence and Multilayer Perceptron for Groundwater Management: A Geoscientific Study on Birbhum District, West Bengal, India (Niladri Das, Subhasish Sutradhar, Ranajit Ghosh, Prolay Mondal) -- Chapter 23. Water resources management in semi-arid Purulia District of West Bengal, in the context of sustainable development goals (Amit Bera, Shubhamita Das).
    Abstract: This volume advances the scientific understanding, development, and application of geospatial technologies related to groundwater resource management, mapping, monitoring, and modelling using up-to-date remote sensing and GIS techniques. The book further provides a critical analysis of the debates and discourses surrounding groundwater resources and society, illustrates the relationship between groundwater resources and precision agriculture for societal development, and describes novel, region-specific management strategies and techniques for sustainability with case studies. The book is organized into three parts: (I) Groundwater resources and societal development; (II) Groundwater availability, quality and pollution; and (III) Sustainable groundwater resources management. Each section begins with a short introduction that includes an overview of the papers in that section. Individual chapters focus on the core themes of research and knowledge along with some topics that have received lesser attention. The book will be of interest to water resource planners and decision-makers, academic researchers, policy makers, NGOs, and academic researchers and students in Geography, Geophysics, Hydrology, Remote Sensing & GIS, Agriculture, Soil Science, and Agronomy.
    Type of Medium: Online Resource
    Pages: XVI, 534 p. 215 illus., 199 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030641368
    URL: https://doi.org/10.1007/978-3-030-64136-8
    DOI: 10.1007/978-3-030-64136-8
    DDC: 551.48
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  • 16
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    Reclaiming and Rewilding River Cities for Outdoor Recreation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Urban ecology (Biology). ; Sociology, Urban. ; Biotic communities. ; Tourism. ; Management. ; Water. ; Urban Ecology. ; Urban Sociology. ; Ecosystems. ; Tourism Management.
    Description / Table of Contents: Introduction. Reclaiming and rewilding river cities for outdoor recreation -- Cities and their waterways -- With rivers to the sea: Ecological restoration of rivers and estuaries and nature-based activities -- Behind good ecological status, the quest to reconquer water territories -- Planning and designing facilities that enhance rivers and encourage the development of tourist and recreational spaces: urban promenades -- Outdoor leisure activities at odds with the city. Arcachon Bay and the Massif des Calanques -- “On the conquest of wild nature” ... but what is meant by ‘nature’? -- The Darsena di Milano (Italy): ‘restoration’ of an urban artificial aquatic environment between citizens' hopes and municipal projects -- Grenoble, the river city facing the mountains (End 19th century-1930s) -- The role and significance of the recreational reconquest of port spaces: Rouen (France), reinvention at the neck of the estuary -- Recreational Activities, Economic and Territorial Development: Caen (France) in the Reconquest of its River? -- Bordeaux’s playful and sporty maritime life: a revolution of venues and activities.
    Abstract: The introduction of sports and recreational facilities into natural environments calls for reflection on their impact on fragile ecosystems. This book is unique in providing an interdisciplinary approach to the ecological restoration of urban and industrial degraded habitats and their use by nearby city-dwellers. For the first time ecologists, sociologists and anthropologists have worked together on particularly sensitive ecosystems such as rivers and estuaries to propose recovery strategies that allow their basic ecological functions to be restored, and which can benefit local populations through nature activities. Nonetheless, the use of natural spaces calls for the building of sustainable towns. This is why this book is distinctive in considering quality of life and well-being as stated objectives of modern river towns. Recently, leisure time has become a part of urban rhythms. In order to favour personal development, an extensive palette of leisure activities is considered by the authors: bird watching entertainment sports culture Many aspects including physical and psychological attributes in relation to the contemporary socio-political fabric are dealt with. While creating areas of freedom, landscaping also induces certain forms of practice and encourages certain social skills. Conversely, the book questions certain types of management based on mass consumption. Don’t they, in the end, aim to satisfy needs that are impermanent and shallow? The image of the contemporary town relies on urban planning projects which, in a global economy, seek to capture the interest of tourists and local populations. How can suitable, diligent planning be successfully combined with both creative design and ecological care? This book demonstrates how biology and sociology can (and should) work in harmony in order to promote an ecosystem approach to environmental management.
    Type of Medium: Online Resource
    Pages: V, 104 p. 38 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030487096
    Series Statement: Estuaries of the World,
    URL: https://doi.org/10.1007/978-3-030-48709-6
    DOI: 10.1007/978-3-030-48709-6
    DDC: 551.48
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  • 17
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    Online Resource
    Climate Change Impacts on Water Resources : Hydraulics, Water Resources and Coastal Engineering (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Earth sciences. ; Physical geography. ; Natural disasters. ; Water. ; Earth Sciences. ; Earth System Sciences. ; Natural Hazards.
    Description / Table of Contents: Trend analyses of seasonal mean temperature Series pertaining to Tapi river basin, using monthly data -- . Dry and wet spell characterization of Naini river basin, western Maharashtra, India -- Assessment of Climate Change on Crop Water Requirement in Tandula Command of Chhattisgarh (India) -- Impact of climate change on hydrological regime of Narmada river basin -- Climate change impacts on water resource in Ethiopia -- Spatio-temporal trend analysis of long term IMD gridded precipitation in Godavari river basin, India -- Forecasting reference evapotranspiration using artificial neural network for Nagpur Region -- Assessment of extremes using time varying downscaling model -- Assessment of impact of land use land cover and climate change on quality of river using water quality index -- Assessment of tail behavior of probability distributions of daily precipitation data over India -- Probabilistic prediction of monthly streamflow using graphical modeling approach. .
    Abstract: This book provides insights and a capacity to understand the climate change phenomenon, its impact on water resources, and possible remedial measures. The impact of climate change on water resources is a global issue and cause for concern. Water resources in many countries are extremely stressed, and climate change along with burgeoning populations, the rise in living standards, and increasing demand on resources are factors which serve to exacerbate this stress. The chapters provide information on tools that will be useful to mitigate the adverse consequences of natural disasters. Fundamental to addressing these issues is hydrological modelling which is discussed in this book and ways to combat climate change as an important aspect of water resource management.
    Type of Medium: Online Resource
    Pages: XVI, 551 p. 223 illus., 199 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030642020
    Series Statement: Water Science and Technology Library, 98
    URL: https://doi.org/10.1007/978-3-030-64202-0
    DOI: 10.1007/978-3-030-64202-0
    DDC: 551.48
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  • 18
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    Online Resource
    Emerging Contaminants Vol. 2 : Remediation (2021)
    Cham :Springer International Publishing :
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    Keywords: Water. ; Hydrology. ; Pollution. ; Environmental chemistry. ; Refuse and refuse disposal. ; Water. ; Pollution. ; Environmental Chemistry. ; Waste Management/Waste Technology.
    Description / Table of Contents: Preface -- Chapter 1 Emerging Contaminants: Remediation -- Chapter 2 Electrochemical Treatments for the Removal of Emerging Contaminants -- Chapter 3 Technologies to Remove Selenium From Water and Wastewater -- Chapter 4 Advanced Treatments for the Removal of Alkylphenols and Alkylphenol Polyethoxylates from Wastewater -- Index.
    Abstract: Emerging contaminants are chemical and biological agents for which there is growing concern about their potential health and environmental effects. The threat lies in the fact that the sources, fate and toxicology of most of these compounds have not yet been studied. Emerging contaminants, therefore, include a large number of both recently discovered and well-known compounds such as rare earth elements, viruses, bacteria, nanomaterials, microplastics, pharmaceuticals, endocrine disruptors, hormones, personal care products, cosmetics, pesticides, surfactants and industrial chemicals. Emerging contaminants have been found in many daily products, and some of them accumulate in the food chain. Correlations have been observed between aquatic pollution by emerging contaminants and discharges from wastewater treatment plants. Most actual remediation methods are not effective at removing emerging contaminants. This second volume presents comprehensive knowledge on emerging contaminants with a focus on remediation.
    Type of Medium: Online Resource
    Pages: XVI, 401 p. 65 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030690908
    Series Statement: Environmental Chemistry for a Sustainable World, 66
    URL: https://doi.org/10.1007/978-3-030-69090-8
    DOI: 10.1007/978-3-030-69090-8
    DDC: 551.48
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  • 19
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    Online Resource
    Development and Implementation of Ship BWMS (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Water. ; Hydrology. ; Marine engineering. ; Water. ; Marine Engineering.
    Description / Table of Contents: Introduction -- Ship ballast water management system -- Working Principle of ballast water management system -- The key components of the system and the working principle of the unit -- Design method of key components -- Optimization of key components -- Development of control system for ballast water management system -- Maintenance and management of ballast water management system -- Implementation of ballast water management system on ships.
    Abstract: This book introduces the components and principles of the common ballast management systems. The working principles of different filtration, cleaning and sterilizing equipment are also introduced. The calculation norm of the construction design and the calculation method of simulation are described. Besides, different aspects of system management are analyzed. The principle of various detecting sensors, the hardware of control system and the design method of human–computer interface are respectively introduced. Last but not least, the maintenance and management of ballast water management system are described, mainly the maintenance and management of key components which composes the system. .
    Type of Medium: Online Resource
    Pages: IX, 285 p. 233 illus., 172 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813368651
    URL: https://doi.org/10.1007/978-981-33-6865-1
    DOI: 10.1007/978-981-33-6865-1
    DDC: 551.48
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  • 20
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    Online Resource
    Climate Impacts on Water Resources in India : Environment and Health (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental health. ; Environmental monitoring. ; Bioclimatology. ; Refuse and refuse disposal. ; Water. ; Environmental Health. ; Environmental Monitoring. ; Climate Change Ecology. ; Waste Management/Waste Technology.
    Description / Table of Contents: Foreword -- Preface -- 1. Water Pollution and Water Quality Assessment, Environmental Flows -- 2. Water Treatment Technologies and Management -- 3. Climate Change and Climate Variability -- 4. Water and Human Health Issues -- 5. Conclusions. .
    Abstract: This book chiefly focuses on environmental flow, water pollution and water quality. Several chapters also cover water treatment technologies and management. In today’s context, climate change and climate variability are important issues in the water sector, which is called upon to develop adaptation strategies to cope with their negative impacts. Human health depends upon the quality of water used for drinking and irrigation purposes. These core issues are discussed and addressed in several chapters. The book explores the impact of climate change on water resources and considers various climatological scenarios. In this regard, it carries out a trend analysis and compares the performance of various Global Climate Models (GCMs). Further, it conducts a water quality analysis and water quality mapping so as to provide information on the most vulnerable areas in the context of water quality. Emerging pollutants, generated from paper mills, are identified in order to choose an appropriate treatment technology. Bioremediation techniques are included for the characterization of improved water quality parameters. The book also presents a low-cost treatment technology for fluoride removal, which can help water managers ensure potable water to stakeholders. In terms of maintaining river ecology in the downstream areas of water resources project sites, the book provides a number of case studies on assessment of environmental flows. Advanced treatment technologies that can be highly advantageous for removing water pollutants are presented. Given its scope, the book offers a valuable resource for academics, water resources practitioners, scientists, water managers, environmentalists, administrators, NGOs, researchers and students who are involved in water management with a main focus on water pollution, the environment, climate change and health. .
    Type of Medium: Online Resource
    Pages: XIII, 392 p. 142 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030514273
    Series Statement: Water Science and Technology Library, 95
    URL: https://doi.org/10.1007/978-3-030-51427-3
    DOI: 10.1007/978-3-030-51427-3
    DDC: 551.48
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  • 21
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    Online Resource
    Changjiang Riverine and Estuarine Hydro-morphodynamic Processes : In the Context of Anthropocene Era (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Environmental geography. ; Geomorphology. ; Sedimentology. ; Geology. ; Landscape ecology. ; Water. ; Integrated Geography. ; Geomorphology. ; Sedimentology. ; Geology. ; Landscape Ecology.
    Description / Table of Contents: Changjiang River basin Overview -- Hydrological Processes of the Changjiang River -- Lake hydro-morphodynamic Processes of the Changjiang River -- Channel sediment-dynamics along the mid-lower reach of the Changjiang River -- Tidal flat morphodynamics of the Changjiang Estuary -- Changjiang Estuary modern morphodynamic processes -- Estuarine submerged delta modern morphodynamics -- Morphodynamic couplings between river and delta.
    Abstract: This book provides a comprehensive and systematic analysis of the morphodynamic process of the Changjiang River from upstream to estuary in the Anthropocene. As the longest river in China, the Changjiang River has nurtured Chinese civilization with ample natural resources for thousands of years. Evidence highlights that the Changjiang River has experienced intensive human interference and indicated dramatic changes in the Anthropocene, including “no flood in flood season, no dry in dry season” in discharge; “less flood in flood season, more dry in dry season” in sediment; riverbed shifts from accretion to erosion; lakes in the middle-lower reach turn from sediment sink to source; estuarine tidal flat exhibits self-organization characteristics and maintains the current accretion state; estuarine branches that connect to the sea show district morphodynamic patterns; and depocenters of the submerged delta indicate periodic shifts. The book stresses that dam construction upstream, practically the Three Gorges Dam, the world’s largest hydraulic engineering project, has significant influences on the hydrology and geomorphology of the middle-lower reach but has a slight effect on estuarine delta development. The geomorphological structure of the estuarine channel is dominated by local land reclamation, navigation, and dredging. This book clarifies the river-estuary morphodynamics of the Changjiang River and indicates the general features of global mega rivers under human interference as well as their own response mechanisms. This book also exhibits the potential risk of river-estuary deltas in the future, as both material and dynamics are experiencing acceleration adjustment.
    Type of Medium: Online Resource
    Pages: XXI, 358 p. 247 illus., 237 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811637711
    URL: https://doi.org/10.1007/978-981-16-3771-1
    DOI: 10.1007/978-981-16-3771-1
    DDC: 551.48
    Language: English
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  • 22
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    Online Resource
    Salt-affected Soils and Marginal Waters : Global Perspectives and Sustainable Management (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Agriculture. ; Pollution. ; Sustainability. ; Environmental management. ; Water. ; Agriculture. ; Pollution. ; Sustainability. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Nature and Origin of Salts, Classification, Area and Distribution of Salt-affected Soils -- Chapter 2. Saline Soils -- Chapter 3. Management and Reclamation of Saline Soils -- Chapter 4. Biodrainage -- Chapter 5. Alkali Soils -- Chapter 6. Reclamation and Management of Alkali Soils for Crop Production -- Chapter 7. Nutrient Management in Salt-affected Soils -- Chapter 8. Irrigation Water: Quality Criteria -- Chapter 9. Irrigation and Salinity Control -- Chapter 10. Wastewaters as Non-conventional Sources of Irrigation -- Chapter 11. Trees and Grasses as Alternate Strategies for Management of Salt-affected Soils -- Chapter 12. Environmental Impact of Reclamation of Salt-affected Soils and Intensive Irrigated Agriculture.
    Abstract: This book presents systematic scientific appraisal, classification, genesis and viable technologies for reclamation and management of salt-affected soils and marginal quality waters across India and several other countries. Nature, solubility and geo-chemical mobility of salts have been provided as basis for the development of alkali and saline soils and groundwaters under specific agro-hydro-ecological regions. Chemical amendment (gypsum) based reclamation technology of alkali soils and related pre and post-reclamation water, nutrient and crop management interventions, including re-sodification issues have been comprehensively addressed. Features and operational guidelines of surface, subsurface, vertical and bio-drainage systems have been thoroughly discussed; likewise, amelioration of irrigation induced saline soils in inland and coastal regions and preventive measures for control of salinity and waterlogging along with environmental trade-offs. Practical approaches for amelioration and judicious use of saline, alkali, high SAR- saline and waste waters have been synthesized for different cropping and agro- forestry systems. Emerging issues on use of industrial by-products as amendments for alkali soils, physiological aspects of salt resistance, anatomical and biochemical mechanism of submergence tolerance, specific ion effects of poor quality waters, crop diversification, groundwater recharge, rejuvenation of tsunami affected coastal soils, safety against occurrence of poisonous gas in tube well pits, paddy straw burning and others have been adequately deliberated upon. Combining scientific principles with field experiences, the book is expected to serve as a useful knowledge base for research workers, teachers and students of soil science, agronomy, plant breeding, forestry, irrigation engineering, extension workers, environmentalists and planners associated with reclamation and management of salt affected soils and waters on sustainable basis in developing and developed countries.
    Type of Medium: Online Resource
    Pages: XXII, 714 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030784355
    URL: https://doi.org/10.1007/978-3-030-78435-5
    DOI: 10.1007/978-3-030-78435-5
    DDC: 551.48
    Language: English
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  • 23
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    Online Resource
    Resilience in the English Small-Scale Fishery : Small Fry but Big Issue (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Animal culture. ; Water. ; Animal Science.
    Description / Table of Contents: Chapter 1 : Introduction -- Chapter 2: Interpretive Framework and Methodology -- Chapter 3: The English Inshore Fleet -- Chapter 4: Perceptions of Vulnerability in the English SSF -- Chapter 5: Strategies of Resilience in the English SSF -- Chapter 6: Discussion of the Resilience Strategies -- Chapter 7: Conclusion.
    Abstract: This book is a contribution to our understanding of the worrying situation of small-scale fisheries (SSF) which face marginalisation in most coastal countries. The authors explain why SSF are so pressured; how there has been a powerful backlash against this marginalisation during the last 30 years; what are the main ideational currents supporting this backlash; and what is the enduring value of SSF that justifies that support. The authors discuss the major contemporary interpretations of SSF; the challenges facing SSF globally and in England; and SSF’s coping strategies in response to those challenges through the framework of resilience theory. In an innovative analysis, the authors show how there are three kinds of resilience: passive resilience (where fishers are resigned to their adverse fate), adaptive resilience (where fishers make the best use of the opportunities that are available to them), and transformative resilience (where fishers attempt to change the system that faces them). The authors draw on an extensive range of interview data to provide rich insights into the world of SSF, and they discuss a variety of proposals for improving their conditions. The book will appeal to the growing academic and public community that is following with increasing concern the debate about the future of SFF, and to the environmental movement which has committed itself to support SSF as a greener form of fishing than the large-scale industrial sector.
    Type of Medium: Online Resource
    Pages: XII, 186 p. 2 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030542450
    URL: https://doi.org/10.1007/978-3-030-54245-0
    DOI: 10.1007/978-3-030-54245-0
    DDC: 551.48
    Language: English
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  • 24
    Online Resource
    Online Resource
    Parched - The Cape Town Drought Story (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Sustainability. ; Environmental management. ; Economic policy. ; Social policy. ; Communication. ; Water. ; Sustainability. ; Environmental Management. ; Socio-Economic Policy. ; Media and Communication.
    Description / Table of Contents: Chapter 1, Introduction -- Chapter 2. Water Supply in Cape Town -- Chapter 3. Reconciliation strategy -- Chapter 4. Politics, trust and governance -- Chapter 5. The Drought -- Chapter 6. Reliance on rainfall, climate variability and climate change -- Chapter 7. The Water Resilience Programme -- Chapter 8. The New Water Programme -- Chapter 9. NWP: Managing dam levels -- Chapter 10. NWP: Managing Demand -- Chapter 11. NWP: Augmentation -- Chapter 12. Lessons learnt -- Chapter 13. Conclusion.
    Abstract: The book presents the history of water supply to Cape Town, leading up to the worst ever drought recorded, through political turmoil impacting on drought interventions and resulting in the adoption of an integrated water strategy. Regions reliant on water supply from rainfed dams have always been vulnerable to the impact of drought. This is exacerbated by the uncertainty of future rainfall, which is never guaranteed, and reliance is placed on modelling using historic data. While weather has always been variable, climate has been generally reliable. With anthropogenic activity causing changes in climate, the validity of modelling based on history is currently not fully trusted. Unless the storage capacity is sufficient to carry through numerous seasons of poor rainfall, even with water restrictions to match demand and supply in times of depleted rainfall, the risk of reservoirs running dry remains a threat.
    Type of Medium: Online Resource
    Pages: XXIX, 290 p. 82 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030788896
    URL: https://doi.org/10.1007/978-3-030-78889-6
    DOI: 10.1007/978-3-030-78889-6
    DDC: 551.48
    Language: English
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  • 25
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    Online Resource
    Nile and Grand Ethiopian Renaissance Dam : Past, Present and Future (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Water-power. ; Environment. ; Geography. ; Water. ; Hydroenergy. ; Environmental Sciences. ; Geography.
    Description / Table of Contents: 1. Introduction -- 2. Pre-colonial, Colonial and Post-Colonial Era: A Look into the Historical Depths of the Nile Waters: What to Learn from History -- 3. Global Perspectives and Regional Lessons: The Nile River and The Prospects of The Grand Ethiopian Renaissance Dam -- 4. Beyond GERD: Hydropolitical, Hydrological, Technological and Investment (HHTI) Imperatives for Sustained Economic Cooperation -- 5. Water Resources Account of Egypt vs Ethiopia's Nile Sub-basins: The Utility of the Concept of Water Budget -- 6. Geographical Dimensions of Hydro-politics: The Case of Nile and Mekong Rivers.
    Abstract: This book is a contribution by the presenters of the 2020 International Conference on the Nile and Grand Ethiopian Renaissance Dam (GERD). The Nile basin is facing unprecedented level of water right challenges after the construction of GERD has begun. Ethiopia, Egypt and Sudan have struggled to narrow their differences on filling and operation of the GERD. The need for science and data-based discussion for a lasting solution is crucial. Historical perspectives, water rights, agreements, failed negotiations, and other topics related to the Nile is covered in this book. The book covers Nile water claims past and present, international transboundary basin cooperation and water sharing, Nile water supply and demand management, Blue Nile/Abbay and Grand Ethiopian Renaissance Dam, land and water degradation and watershed management, emerging threats of the Lakes Region in the Nile Basin, and hydrologic variation and monitoring. This book is beneficial for students, researchers, sociologists, engineers, policy makers, lawyers, water resources and environmental managers and for the people and governments of the Nile Basin.
    Type of Medium: Online Resource
    Pages: IX, 525 p. 158 illus., 147 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030764371
    Series Statement: Springer Geography,
    URL: https://doi.org/10.1007/978-3-030-76437-1
    DOI: 10.1007/978-3-030-76437-1
    DDC: 551.48
    Language: English
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  • 26
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    Online Resource
    The Collectin Protein Family and Its Multiple Biological Activities (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medical microbiology. ; Proteins . ; Immunology. ; Medical Microbiology. ; Protein Biochemistry.
    Description / Table of Contents: 1. Discovering the role of mannose-binding lectin (MBL) in innate immunity: the early history -- 2. Mannose-binding lectin in human health and disease -- 3. The activities of MASPs, complement proteases associated with collectins and ficolins -- 4. Structures of the MASPs and comparison with C1r and C1s -- 5. Biological activities of SP-A and SP-D against extracellular and intracellular pathogens -- 6. Surfactant protein D: A Therapeutic Target for Allergic Airway Diseases -- 7. SP-D in immune surveillance against cancer -- 8.Testicular immune privilege – a recently discovered domain of Collectins -- 9. Role of Collectins in Pregnancy -- 10. Bovine Collectins: Role in Health and Disease -- .
    Abstract: The topic of this book, Collectins, is a family of proteins whose major function is in innate immunity, where Collectins act as pattern recognition receptors (PRRs). In general they recognize targets such as microbial surfaces and apoptotic cells, and once bound to a target, Collectins promote the clearance of microorganisms and damaged host tissue. New cell-surface proteins and glycoproteins, which act as Collectin receptors, are currently being identified. Some Collectins, particularly MBL, activate the complement system, which enhances the ability of antibodies to fight pathogens, via three MBL-associated proteases, the MASPs. Additionally, recent research has begun to show wider-ranging activities of Collectins, such as: · Their role in metabolism, and therefore their involvement in lifestyle diseases such as obesity and cardiovascular disease. · Their ability to modulate the adaptive immune response, as well as to recognize and trigger apoptosis of cancer cells, which makes them effective in the annihilation of cancer cells with multiple mutations. · The regulation of their expression by gonadal steroid hormones implicates them with critical roles in both male and female fertility. · Altered levels of Collectins have been associated with various autoimmune diseases. This book brings together current knowledge of the structure, functions and biological activities of Collectins, to describe their integral role in human health.
    Type of Medium: Online Resource
    Pages: XII, 244 p. 50 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030670481
    URL: https://doi.org/10.1007/978-3-030-67048-1
    DOI: 10.1007/978-3-030-67048-1
    DDC: 571.96
    Language: English
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    Online Resource
    Alternative Medicine Interventions for COVID-19 (2021)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Alternative medicine. ; Virology. ; Therapeutics. ; Nutrition   . ; Food science. ; Immunology. ; Complementary and Alternative Medicine. ; Virology. ; Therapeutics. ; Nutrition. ; Food Science.
    Description / Table of Contents: 1. Introduction to COVID-19 -- 2. Medicinal plants as COVID-19 remedy -- 3. Traditional Chinese Medicines as possibly remedy Against SARS- CoV-2 -- 4. Plant natural products against COVID-19 -- 5. Foods as first defense against COVID-19 -- 6. Drugs for the treatment of COVID-19 -- 7. COVID-19 pandemic and vaccines -- 8. Recent updates in vaccine development against COVID-19 -- 9. Recent developments in therapeutic approaches against COVID-19.
    Abstract: This research volume examines the available alternative, complementary, pharmaceutical and vaccine methods for treating, mitigating, or preventing COVID-19. Coverage includes traditional Chinese medicine, herbal remedies, nutraceutical/dietary options, and drug/vaccine therapies. All the methods discussed will be critically examined to provide readers with a full, unbiased overview that includes pros/cons of each method. While the nature of COVID-19 is still being studied, and new research and theories are being published daily, this book endeavors to provide readers with a comprehensive summary of current research on alternative and mainstream treatment and prevention methods. .
    Type of Medium: Online Resource
    Pages: XII, 284 p. 120 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030679897
    URL: https://doi.org/10.1007/978-3-030-67989-7
    DOI: 10.1007/978-3-030-67989-7
    DDC: 571.96
    Language: English
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  • 28
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    Online Resource
    Advances in Host-Directed Therapies Against Tuberculosis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Diseases. ; Therapeutics. ; Immunology. ; Diseases. ; Therapeutics.
    Description / Table of Contents: Section 1: Introduction -- Chapter 1: Introduction: An overview of host-directed therapies for tuberculosis -- Section 2: Targeting immunometabolism -- Chapter 2: Sirtuin deacetylases: Linking Mycobacterial infection and host metabolism -- Chapter 3:The mammalian target of rapamycin complex 1 (mTORC1): an ally of M. tuberculosis in host cells -- Chapter 4: HIF-1α as a potential therapeutic target for tuberculosis treatment -- Chapter 5: Nuclear receptors in host-directed therapies against tuberculosis -- Section 3: Enhancing anti-mycobacterial mechanisms -- Chapter 6: Autophagy as a target for host-directed therapy against tuberculosis -- Chapter 7: Metformin: a leading HDT candidate for TB -- Chapter 8: Statins as host-directed therapy for tuberculosis -- Chapter 9: Antimycobacterial attributes of mitochondria: An insight into host defense mechanisms -- Section 4: Targeting immune cells -- Chapter 10: Conventional and unconventional lymphocytes in immunity against Mycobacterium tuberculosis -- Chapter 11: Targeting inhibitory cells such as Tregs and MDSCs in the tuberculous granuloma -- Chapter 12: Targeting suppressor T cells -- Chapter 13: Neutrophil-mediated mechanisms as targets for host-directed therapies against tuberculosis -- Chapter 14: Type I interferon and interleukin-1 driven inflammatory pathways as targets for HDT in tuberculosis -- Chapter 15: Mucosal-associated invariant and Vγ9Vδ2 T cells -- Chapter 16: Airway epithelial cells.-Section 5: Preclinical models for assessing HDTs -- Chapter 17: In vitro models of human granuloma formation to analyze host-directed therapies -- Chapter 18: C3HeB/FeJ as a key mouse strain for testing host-directed therapies against tuberculosis -- Chapter 19: The Rabbit Model for Assessing Host-Directed Therapies for Tuberculosis -- Section 6: Clinical trials of HDTs and special considerations for study endpoints -- Chapter 20:Clinical trials of TB-HDT candidates -- Chapter 21:Outcomes for clinical trials of host-directed therapies for tuberculosis -- Chapter 22: Pharmacological considerations for clinical trials of host-directed therapies for tuberculosis.
    Abstract: This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms investigated are either protective – thus calling for pathway/factor enhancing drugs – or maladaptive – thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.
    Type of Medium: Online Resource
    Pages: XIII, 332 p. 20 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030569051
    URL: https://doi.org/10.1007/978-3-030-56905-1
    DOI: 10.1007/978-3-030-56905-1
    DDC: 571.96
    Language: English
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    Online Resource
    Close Encounters of the Microbial Kind : Everything You Need to Know About Common Infections (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medical sciences. ; Virology. ; Diseases. ; Patient education. ; Immunology. ; Health Sciences. ; Virology. ; Diseases. ; Patient Education.
    Description / Table of Contents: 1. Microbes and infectious diseases -- 2. Acne -- 3. Skin abscesses (boils) -- 4. Dandruff -- 5. Fungal nail infections -- 6. Fungal infections of the skin -- 7. Chickenpox -- 8. Shingles -- 9. Common warts -- 10. The common cold -- 11. Influenza -- 12. Sore throat -- 13. Coronavirus disease-2019 -- 14. Acute sinusitis -- 15. Chronic sinusitis -- 16. Otitis media (middle ear infection) -- 17. Otitis externa (swimmers ear) -- 18. Acute bronchitis (chest cold) -- 19. Conjunctivitis (pink eye) -- 20. Tooth decay (caries) -- 21. Gum disease -- 22. Bad breath -- 23. Oral thrush -- 24. Oral herpes -- 25. Cystitis (lower urinary tract infection) -- 26. Vaginitis -- 27. Chlamydia -- 28. Gonorrhoea -- 29. Genital herpes -- 30. Genital warts -- 31. Syphilis -- 32. Gastroenteritis due to Campylobacter -- 33. Gastroenteritis due to Salmonella -- 34. Gastroenteritis due to Clostridium perfringens -- 35. Gastroenteritis due to Norovirus -- 36. Gastroenteritis due to Rotavirus.
    Abstract: Microbes – can’t live with them, can’t live without them. Increasingly, we’re finding out that our microbiota (the microbes that live on us) are essential for our wellbeing – they provide us with nutrients and vitamins and play a key role in developing our immune system. On the other hand, they are responsible for a great deal of misery, as they are major causes of death and debility around the world. As well as our own microbiota turning against us, there are lots of other microbes out in the wider world that can seriously damage, or even kill, those they infect. The current pandemic of COVID-19 shows the devastating effect that an infectious disease can have – our lives have been turned upside down. If you live in a developed country, you’re not likely to get killer diseases such as ebola and cholera, but you do have a high chance of catching other infections that can have a significant impact on your wellbeing. This book focuses on those infections you’re most likely to go down with, and supplies the answers to the following questions about them: Which infectious diseases are we likely to come across? How common are they? What microbes cause them? What happens to our bodies during an infection? How are the resulting illnesses treated? How can we avoid getting them? This book covers nearly 60 infectious diseases that people living in developed countries are likely to experience at some point during their life. It also has an introductory chapter that describes, in everyday language, the basic principles of microbiology and infectious diseases. Each chapter is lavishly illustrated, has interesting, relevant inserts, and provides a list of web-accessible suggestions for further reading.
    Type of Medium: Online Resource
    Pages: XV, 526 p. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030569785
    URL: https://doi.org/10.1007/978-3-030-56978-5
    DOI: 10.1007/978-3-030-56978-5
    DDC: 571.96
    Language: English
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    Online Resource
    Microbial Pathogenesis : Infection and Immunity (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Pharmacology. ; Internal medicine. ; Immunology. ; Pharmacology. ; Internal Medicine.
    Description / Table of Contents: 1.Human Papillomavirus-associated cancers -- 2. Mechanisms of immune evasion by Ebola virus -- 3. Innate immune mechanisms against HIV-1 -- 4. Current insights into the host immune response to respiratory viral infections -- 5. Immune responses to MERS-CoV in humans and animals -- 6. SARS-CoV-2: Pathogenesis and host-pathogen interaction -- 7. Antibiotic Resistance mechanisms and their transmission in Acinetobacter baumannii -- 8. Pathogenesis and host immune response in leprosy -- 9. Innate immunity and tuberculosis -- 10. Vaccination strategies against Mycobacterium tuberculosis: BCG and beyond -- 11. Candida pathogenicity and interplay with the immune system -- 12. Immune responses in Malaria and vaccine strategies.
    Abstract: This book updates in detail the microbial pathogenesis of various important pathogens, including HIV-1, MERS, SARS-CoV-2, Mycobacterium and Plasmodium. There is also a general discussion of the innate and adaptive immune responses against primary and opportunistic infections. The overall purpose of the book is to aid in the development of anti-viral and anti-microbial targets.
    Type of Medium: Online Resource
    Pages: XIII, 291 p. 35 illus., 33 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030674526
    Series Statement: Advances in Experimental Medicine and Biology, 1313
    URL: https://doi.org/10.1007/978-3-030-67452-6
    DOI: 10.1007/978-3-030-67452-6
    DDC: 571.96
    Language: English
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  • 31
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    Complex Systems and Computational Biology Approaches to Acute Inflammation : A Framework for Model-based Precision Medicine (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Bioinformatics. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: 1. An Overview of the Translational Dilemma and the Need for Model-based Precision Medicine -- 2 Translational Equation-based Modeling -- 3. Agent-based Modeling in Translational Systems Biology -- 4. Integrating Data-driven and Mechanistic Modeling in Sepsis and Trauma -- 5. Therapeutics as Control: Model-based approaches for control discovery -- 6. Disorder of Systemic Inflammation in Sepsis and Trauma: A Systems Perspective -- 7. Multi-scale equation-based models: Insights for Inflammation and Physiological Variability -- 8. In silico Trials and Personalized Therapy for Sepsis and Trauma -- 9. Computational Modeling of the Coagulation Response -- 10. Disorder of Localized Inflammation in Wound Healing -- 11. Equation-based Models of Wound Healing and Collective Cell Migration -- 12. Agent-based Models of Wound Healing -- 13. Tissue realistic translational modeling of gut inflammation -- 14. Data-Driven Modeling of Liver Injury, Inflammation, and Fibrosis -- 15. Computational Modeling of Tuberculosis -- 16. The Rationale and Implementation of Model-based Precision Medicine for Inflammatory Diseases -- Index.
    Abstract: This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.
    Type of Medium: Online Resource
    Pages: IX, 312 p. 51 illus., 37 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030565107
    URL: https://doi.org/10.1007/978-3-030-56510-7
    DOI: 10.1007/978-3-030-56510-7
    DDC: 571.96
    Language: English
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    Online Resource
    Immunology: Overview and Laboratory Manual (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Immunology. ; Biomedical Research.
    Description / Table of Contents: Part I: Overview of Immunity -- Ch 1: Immunity -- Ch 2: Components of immunity -- Ch 3: Hematopoiesis -- Ch 4: The Immune system: pathogen sensing and detection -- Ch 5: Lymphoid organs -- Ch 6: Innate and Adaptive immunity -- Ch 7: Leukocyte homing, migration and recirculation -- Ch 8: Apoptosis -- Ch 9: Antigens -- Ch 10: B cell development, activation and immunoglobulin structure -- Ch 11: Immunoglobulin and T cell receptor gene rearrangements -- Ch 12: Major histocompatibility complex proteins -- Ch 13: T cell development and T cell receptor structure -- Ch 14: Cytokines -- Ch 15: Lymphocyte signals -- Ch 16: Complement fixation -- Ch 17: Cell mediated immunity -- Ch 18: Hypersensitivities -- Ch 19: Parasite Immunity -- Ch 20: Vaccines -- Ch 21: Transplantation -- Ch 22: Immune regulation and autoimmunity -- Ch 23: Immunodeficiencies -- Ch 24: Cancer -- Ch 25: Practice questions -- Ch 26: Study guide for exam. Part II. Laboratory Manual -- 27. Immunology laboratory policies -- 28. Instructions for notebook entries -- 29. Instructions for writing lab reports -- 30. Lab report topics -- 31. Exercise 1: Using a compound microscope -- 32. Exercise 2: Pipetting and dilution technique, identification of mouse lymphoid organs -- 33. Exercise 3: Blood Cell Preparation, Leukocyte differentiation and ABO Blood Typing -- 34. Exercise 4: Single Suspension of Mouse Spleen cells, Cell Viability Assays, and Identification of specific cells using surface antigens -- 35. Exercise 5: Isolation of mouse peritoneal macrophages: In vitro phagocytosis of bacterial cells -- 36. Exercise 6: Clearance of bacteria from mouse blood by the RES -- 37. Exercise 7: Hemolytic Plaque assay (The Jeme Plaque Assay) -- 38. EXERCISE 8: Rabbit and Mouse Immunizations- Preparation of Polyclonal antibodies and screening assays -- 39. EXERCISE 9: Determination of Antibody Titer: Screening Techniques -- 40. EXERCISE 10: Immunodiffusion and Immunoelectrophoresis -- 41. EXERCISE 11: Protein Affinity Purification of Rabbit IgG -- 42. EXERCISE 12: Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE) -- 43. EXERCISE 13: Immunoblotting (Western Blotting) -- 44. Exercise 14: Protein Assay -- 45. Exercise 15: Enzyme-linked Immunosorbent Assay (ELISA) -- 46. EXERCISE 16: Enzyme-Linked Immunospot Assay (ELISPOT) -- 47. EXERCISE 17: Immunofluorescence assay (IFA) -- 48. EXERCISE 18: Flow Cytometry -- 49.EXERCISE 19: Complement Fixation Assays -- 50. Tissue Cell Culture Techniques -- 51. EXERCISE 20: Mitogen Induced Response of Lymphocytes: Detection of Band T cell Lymphocytes Using Immunofluorescence -- 52. Exercise 21: Induction of IL-2 Secretion from Mouse Lymphoma Cells -- 53. EXERCISE 22: Adoptive Transfer of Lymphocytes: Band T cell Cooperation for Antibody Production -- 54. EXERCISE 23: Macrophage Migration Inhibition -- 55. EXERCISE 24: Monoclonal Antibody Preparation -- 56. EXERCISE 25: Immunization of mice with a recombinant protein -- 57. EXERCISE 26: Polarization of T helper cells into TH1 subset -- 58. Exercise 27: Immunoprecipitation -- 59. EXERCISE 28: Induction of apoptosis in T lymphocytes and detection of apoptotic markers -- 60. EXERCISE 29: Cloning and sequencing of cDNAs of mouse variable regions of H and L chains of monoclonal antibodies -- Appendix -- Sample Practice Questions.
    Abstract: A two-in-one text providing teaching lab students with an overview of immunology as well as a lab manual complete with current standard exercises. Section I of this book provides an overview of the immune system and immunity, and includes review questions, problem sets, case studies, inquiry-based questions, and more to provide students with a strong foundation in the field. Section II consists of twenty-two lab exercises focused on key concepts in immunology, such as antibody production, cell separation, cell function, immunoassays, Th1/Th2 cytokine detection, cell and tissue culture methods, and cell and molecular biology techniques. Appendices include safety information, suggested links and readings, and standard discipline processes, protocols, and instructions.
    Type of Medium: Online Resource
    Pages: XX, 471 p. 61 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030646868
    URL: https://doi.org/10.1007/978-3-030-64686-8
    DOI: 10.1007/978-3-030-64686-8
    DDC: 571.96
    Language: English
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    Online Resource
    T Regulatory Cells in Human Health and Diseases (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Cytology. ; Immunology. ; Biomedical Research. ; Cell Biology.
    Abstract: This book addresses one of the major challenges of immunology today that is being directed to the translation of the rapidly emerging volume of basic science contributions of immunology to clinical medicine. In so doing, the book systemically introduces and discusses concepts, classifications, phenotypic and functional descriptions of regulatory T (Treg) cells in health and disease. The authors of the 15 chapters were selected from among the most qualified experts in the field of Treg cell research who provide a comprehensive overview of Treg cells and their biology in the ensuing chapters. The beginning chapters provide a useful contemporary classification of Treg cell populations and then progress to chapters that explore basic mechanisms of Treg cell function and epigenetic control. In addition to descriptions of typical CD4+ Foxp3+ cells, other chapters provide detailed presentations of Treg subsets such as CD8+ Tregs and IL-10-producing Tr1 cells. The differences of various Treg subsets, as well as circulating and resident Treg cell populations, are next compared. Importantly, the next chapters provide the clinical correlation of Treg cells with autoimmune diseases, inflammatory diseases, metabolic diseases, cancer and organ transplantation and progress to chapters that highlight emerging innovative technology including nanoparticle-Treg cells and their translational values. In summary, the book will provide a valuable resource not only for graduate students and researchers in the fields of immunology, cell biology and translational medicine but also for all others interested in learning more about Treg cells and their application in human health and disease.
    Type of Medium: Online Resource
    Pages: X, 302 p. 35 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811564079
    Series Statement: Advances in Experimental Medicine and Biology, 1278
    URL: https://doi.org/10.1007/978-981-15-6407-9
    DOI: 10.1007/978-981-15-6407-9
    DDC: 571.96
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    Online Resource
    Bone Marrow Niche : Microenvironments Critical for Immune Cell Development (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Stem cells. ; Medicine Research. ; Biology Research. ; Human physiology. ; Immunology. ; Stem Cell Biology. ; Biomedical Research. ; Human Physiology.
    Description / Table of Contents: Preface -- Skeletal stem cells as the developmental origin of cellular niches for hematopoietic stem and progenitor cells -- Cellular niches for hematopoietic stem cells and lympho-hematopoiesis in bone marrow during homeostasis and blood cancers -- Remodeling of the bone marrow stromal microenvironment during pathogenic infections -- The Roles of IL-7 and IL-15 in Niches for Lymphocyte Progenitors and Immune Cells in Lymphoid Organs -- Lymph node stromal cells: diverse meshwork structures weave functionally subdivided niches -- Immune Niche within the Peritoneal Cavity.
    Abstract: This volume summarizes recent advances in research on mesenchymal cell populations in the bone marrow. It explores how mesenchymal cells create niches for immune cells in extramedullary organs and it discusses new concepts of lympho-hematopoietic microenvironments. Readers are introduced to the fundamentals of hematopoietic stem cells (HSCs) differentiation to all types of blood cells, including immune cells, in the bone marrow. The book highlights how this process is supported and regulated by the individual microenvironments of stem cells, termed niches. The identity of HSC niches has been subject to longstanding debates. Recent studies identified the population of mesenchymal stem cells as the major cellular component of niches, for hematopoietic stem and progenitor cells (HSPCs) and their candidate developmental origin. Furthermore, candidate cellular niches for immune cells in lymph nodes and adipose and connective tissues were identified. The authors of this volume focus on shared features between those and HSPC niche cells in the bone marrow. Covering latest research results, this book serves as fascinating read for researchers and clinicians in hematology and immunology.
    Type of Medium: Online Resource
    Pages: VII, 134 p. 19 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030860165
    Series Statement: Current Topics in Microbiology and Immunology, 434
    URL: https://doi.org/10.1007/978-3-030-86016-5
    DOI: 10.1007/978-3-030-86016-5
    DDC: 571.96
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    Online Resource
    Three Dimensional Human Organotypic Models for Biomedical Research (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Cancer. ; Regenerative medicine. ; Stem cells. ; Cytology Technique. ; Immunology. ; Cancer Biology. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology. ; Cytological Techniques.
    Description / Table of Contents: Introduction: Rationale of using skin models in research -- Skin anatomy (human and animals for experimental research) -- In vivo skin models -- In vitro human skin models (Skin equivalents vs skin explants) -- Human skin models for studying cutaneous infections -- Skin animal models for pharmacological research -- Human skin models for pharmacological research -- Human skin models for allergological research -- Human skin models for cancer research -- Human skin models for vaccine research.
    Abstract: This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 265 p. 22 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030624521
    Series Statement: Current Topics in Microbiology and Immunology, 430
    URL: https://doi.org/10.1007/978-3-030-62452-1
    DOI: 10.1007/978-3-030-62452-1
    DDC: 571.96
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    Towards Water Secure Societies : Coping with Water Scarcity and Quality Challenges (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environment. ; Pollution. ; Water. ; Environmental Sciences. ; Pollution.
    Description / Table of Contents: Introduction -- Water Security Assessment for the Red – Thai Binh River Basin, Vietnam -- Contextualizing Farmers’ Perceptions of Agricultural Wastewater Reuse in Areas of Water Shortage and Contamination: An In-depth Case Study of Wadi Al-Far`a Watershed – Palestine -- Optimize Anaerobic Degradation Processes in Agricultural Wastewater Treatment to maximize Biogas Productivity -- Evaluation of Wastewater Treatment using Dilution in Rosetta Branch and Tala Drain, Nile Delta, Egypt -- Upcoming Challenges of Water Reclamation fromUnconventional Sources -- How Membrane Bioreactor Technology Can Help to Solve both, German and RussianWastewater Problems -- Experiences on Wastewater Treatment and Reuse for Different Types of Industries -- Social Characteristics and Adaptation to Water Scarcity: The Case of Groundnut Farmers in the Lawra and Nandom Districts, Ghana -- Temporal Climate Variability and Staple Cereals in Southern Burkina Faso.
    Abstract: This book describes the water security challenges with focus on water scarcity and quality in our rapidly changing world. Achieving water security is essential to promoting economic and social development, as well as resource sustainability and ecosystem integrity. Questions of water security are central to recent global agreements such as the Sustainable Development Goals (SDGs), the Paris Agreement on Climate Change, and the Sendai Framework for Disaster Risk Reduction. The thematic areas discussed here support the SDGs, with special attention to Goal 6 (“Ensure availability and sustainable management of water and sanitation”). The book is a collection of studies from engineering, social and environmental disciplines and aims at giving a balanced overview of the current , complex discourse on water scarcity and quality. It offers a source of inspiration and information for researchers, policymakers, planners, and practitioners concerning the further development of concepts, approaches, and methodologies for promoting water secure societies.
    Type of Medium: Online Resource
    Pages: XIII, 200 p. 90 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030506537
    URL: https://doi.org/10.1007/978-3-030-50653-7
    DOI: 10.1007/978-3-030-50653-7
    DDC: 551.48
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    Water Resilience : Management and Governance in Times of Change (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental management. ; Pollution. ; Earth sciences. ; Environment. ; Water. ; Environmental Management. ; Pollution. ; Earth Sciences. ; Environmental Sciences.
    Description / Table of Contents: Part I: Introduction -- Chapter 1. The Emergence of Water Resilience: an introduction -- Part II: Examining water systems through the lens of resilience -- Chapter 2. Water Policy and Governance in Transition: The EU Water Framework Directive -- Chapter 3. The Sustainable Groundwater Management Act (SGMA)—California’s Prescription for Common Challenges of Groundwater Governance -- Chapter 4. Water Policy Reform for Sustainable Development in the Murray-Darling Basin, Australia: Insights from Resilience Thinking -- Chapter 5. Reducing Nutrient Loading from Agriculture to Lake Ecosystems – Contributions of Resilience Principles -- Chapter 6. Reconfiguring water governance for resilient social-ecological systems in South America -- Part III: Exploring the conceptual boundaries and bridges of water resilience -- Chapter 7. Capacities for watershed resilience: persistence, adaptation, and transformation -- Chapter 8. Adaptive Governance in North American Water Systems: a legal perspective on resilience and reconciliation -- Chapter 9. Cross-scale Governance for Urban Water Resilience in Bengaluru and Cape Town -- Chapter 10. Facing Change: Understanding Transitions of River Basin Policies Over Time -- Chapter 11. Conditions and Cautions for Transforming Ocean Governance -- Chapter 12. Extraordinary governance to avoid extraordinary events. Part IV: Conclusion -- Chapter 13. Charting a course for management and governance dimensions of water resilience.
    Abstract: This book synthesizes current knowledge and understanding of management and governance in the context of water resilience; advances theory through synthesis of research and experiences from a variety of disciplinary perspectives. The book highlights the implications of theory and experience for innovation in practice and policy; and it explores frontiers and future research. The book further addresses the need for a consolidated, interdisciplinary approach to the theoretical advances and practical implications of water resilience for academics, resource managers, aid organizations, policy makers and citizens. .
    Type of Medium: Online Resource
    Pages: X, 311 p. 23 illus., 18 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030481100
    URL: https://doi.org/10.1007/978-3-030-48110-0
    DOI: 10.1007/978-3-030-48110-0
    DDC: 551.48
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    The Ganga River Basin: A Hydrometeorological Approach (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Climatology. ; Geotechnical engineering. ; Water. ; Climate Sciences. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Water Quality Challenges in Ganga River Basin, India -- Sequential Characterization of Contaminant Plumes using feedback information -- Evaluation of groundwater quality using Multivariate analysis: Rae Bareli District, Ganga Basin, Uttar Pradesh -- A Supervising Grid Model for Identification of Groundwater Pollute -- Study of Methods available for Groundwater and Surfacewater Interaction: A case study on Varanasi, India -- Augmentation of Drinking Water Supply by River Bank Filtration -- River Discharge Study in River Ganga, Varanasi Using Conventional and Modern Techniques -- Review on the Field Applications of River Training Structures for River Bank Protection -- Comparison of conceptual and distributed hydrological Models for runoff Estimation in a River Basin -- Monthly variation in near surface air temperature lapse rate across Ganga Basin, India -- Identification of relationship between precipitation and atmospheric oscillations in Upper Ganga basin -- Utilizing stream networks for regional flood frequency analysis -- Plotting Positions for the Generalized Extreme Value Distribution: A Critique -- Application of Machine Learning Techniques for Clustering of Rainfall Time Series Over Ganges River Basin.
    Abstract: This book presents an overview of the hydrometeorological and hydrological studies and assists in tackling challenges posed by climate and land use land cover changes. The Ganga River is one of the major living streams on the planet earth and very important river system in India. This holy river is a lifeline for approximately five hundred million people. In the last few decades, River Ganges has been subjected to tremendous pressures with respect to both water quantity and water quality. This situation, already one of the alarming magnitudes, has been further provoked by hydrometeorological changes resulting in droughts, floods and reduced groundwater levels and river flows in addition to the poor river health. Thus, it is imperative to assess the various complexities and possible solutions for better management of River Ganges. This book is a valuable addition to the literature and contributes to research on River Ganges which will help better planning and management of Ganga river basin. The hydrological and hydrometeorological aspects covered in this book help practitioners, researchers, policymakers and other stakeholders.
    Type of Medium: Online Resource
    Pages: XVI, 322 p. 119 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030608699
    Series Statement: Society of Earth Scientists Series,
    URL: https://doi.org/10.1007/978-3-030-60869-9
    DOI: 10.1007/978-3-030-60869-9
    DDC: 551.48
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    Essential Tools for Water Resources Analysis, Planning, and Management (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Water. ; Hydrology. ; Mathematical optimization. ; Quantitative research. ; Artificial intelligence Data processing. ; Water. ; Optimization. ; Data Analysis and Big Data. ; Data Science.
    Description / Table of Contents: Modelling and Simulation -- Optimization -- Big data and Databases -- Data mining -- Remote sensing -- Geographical information system -- System dynamics -- Agent-based models -- Game theory -- Conflicts resolution -- Multi-objective optimization -- Multicriteria and multi-attribute decision -- making -- Risk, uncertainty, and reliability.
    Abstract: This book describes tools needed in water resources management, using methods such as optimization algorithms, conflict resolution methods, risk and uncertainty analysis, to better manage water resources and consumption, thus mitigating the present and future global water shortage crisis. It presents the applications of these tools through case studies which demonstrate its benefits of proper management of water resources. This book acts as a reference for students, professors, industrial practitioners and stakeholders in the field of water resources management and hydrology.
    Type of Medium: Online Resource
    Pages: VI, 343 p. 78 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813342958
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-981-33-4295-8
    DOI: 10.1007/978-981-33-4295-8
    DDC: 551.48
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    Advanced Magnetic Adsorbents for Water Treatment : Fundamentals and New Perspectives (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Chemical engineering. ; Water. ; Pollution. ; Chemical Engineering.
    Description / Table of Contents: Preface -- Chapter 1 Fundamentals of Adsorption -- Chapter 2 Methods of Synthesis of Magnetic Adsorbents -- Chapter 3 Magnetic Biosorbents and their Application in Water Remediation -- Chapter 4 Lignocellulosic Wastes as Precursor of carbonaceous magnetic adsorbents of organic and inorganic pollutants adsorption -- Chapter 5 Magnetic Biochar Fibers for Copper Removal -- Chapter 6 Treatment of Landfill Leachate with Magnetic Adsorbents -- Chapter 7 Removal of Emerging Pollutants and Toxic Metals using Magnetic Adsorbents -- Chapter 8 Magnetically Modified Biological Materials for Dyes Removal -- Chapter 9 Regeneration of magnetic adsorbents saturated by organic pollutants using advanced oxidation technologies -- Chapter 10 Magnetic Nanofibers for Contaminants Removal from Water -- Chapter 11 Magnetic solid phase-based sorbents for isolation/pre-concentration and removal of pesticides -- Chapter 12 Characterization and application of Fe-magnetic materials and nanomaterials for application in the aqueous matrices decontamination -- Chapter 13 Advanced Magnetic Adsorbents Prepared from Emulsion Template for Water Treatment -- Chapter 14 Chitosan Based Magnetic Adsorbents -- Chapter 15 Methods used for performance enhancement of iron based magnetic adsorbents in water systems.
    Abstract: This book compiles 15 chapters about the synthesis, characterizations, and application of many kinds of magnetic adsorbents for water treatment. It is devoted to the scientific community that works with adsorption technologies for water treatment and remediation. Specifically, for professors and Ph.D. students. It is expected that this book serves as an interesting background for researchers in the field of magnetic adsorbents for water treatment.
    Type of Medium: Online Resource
    Pages: XVI, 501 p. 117 illus., 78 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030640927
    Series Statement: Environmental Chemistry for a Sustainable World, 61
    URL: https://doi.org/10.1007/978-3-030-64092-7
    DOI: 10.1007/978-3-030-64092-7
    DDC: 551.48
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    Deep Learning for Hydrometeorology and Environmental Science (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Artificial intelligence. ; Environmental sciences Mathematics. ; Environment. ; Neural networks (Computer science) . ; Human ecology Study and teaching. ; Water. ; Artificial Intelligence. ; Mathematical Applications in Environmental Science. ; Environmental Sciences. ; Mathematical Models of Cognitive Processes and Neural Networks. ; Environmental Studies.
    Description / Table of Contents: Introduction -- Mathematical Background -- Data Preprocessing -- Neural Network -- Training a Neural Network -- Updating Weights -- Improving model performance -- Advanced Neural Network Algorithms -- Deep learning for time series -- Deep learning for spatial datasets -- Tensorflow and Keras Programming for Deep Learning -- Hydrometeorological Applications of deep learning -- Environmental Applications of deep learning.
    Abstract: This book provides a step-by-step methodology and derivation of deep learning algorithms as Long Short-Term Memory (LSTM) and Convolution Neural Network (CNN), especially for estimating parameters, with back-propagation as well as examples with real datasets of hydrometeorology (e.g. streamflow and temperature) and environmental science (e.g. water quality). Deep learning is known as part of machine learning methodology based on the artificial neural network. Increasing data availability and computing power enhance applications of deep learning to hydrometeorological and environmental fields. However, books that specifically focus on applications to these fields are limited. Most of deep learning books demonstrate theoretical backgrounds and mathematics. However, examples with real data and step-by-step explanations to understand the algorithms in hydrometeorology and environmental science are very rare. This book focuses on the explanation of deep learning techniques and their applications to hydrometeorological and environmental studies with real hydrological and environmental data. This book covers the major deep learning algorithms as Long Short-Term Memory (LSTM) and Convolution Neural Network (CNN) as well as the conventional artificial neural network model.
    Type of Medium: Online Resource
    Pages: XIV, 204 p. 189 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030647773
    Series Statement: Water Science and Technology Library, 99
    URL: https://doi.org/10.1007/978-3-030-64777-3
    DOI: 10.1007/978-3-030-64777-3
    DDC: 551.48
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    Water Resource Management in Central Asia and Afghanistan : Current and Future Environmental and Water Issues (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Bioclimatology. ; Environmental monitoring. ; Geographic information systems. ; Water. ; Pollution. ; Climate Change Ecology. ; Environmental Monitoring. ; Geographical Information System.
    Description / Table of Contents: Chapter 1: Hydrologic Model for Runoff Simulation of the Kyzyl-Suu River -- Chapter 2: Integrated Water Resources and Environmental Management in the Transboundary Rivers Basins of Central Asia -- Chapter 3: Experience of Preparation of River Basin Planning and Management on Water Resource Development, Use and Protection in Main and Minor Transboundary River Basins -- Chapter 4: Assessment of Amu Darya Runoff Changes as a Result of Predicted Climate Change and Reduced Glaciation -- Chapter 5: Climate Change Forecast in Kyrgyzstan for 2050 and 2100 -- Chapter 6: Reactions and Dynamics of Drains on Small Transboundary Rivers with Various Feeding Types and the Effect on Climate Change -- Chapter 7: Assessment of anthropogenic loads on the Talas River Watershed (within the Republic of Kazakhstan) -- Chapter 8:The Glacial Systems of Kyrgyzstan under Climate Change -- Chapter 9: Water Resource Risks to Cotton Agriculture in Uzbekistan: Climate, Policy and Irrigation -- Chapter 10: Groundwater Flooding Risk Assessment Using Microseismic Arrays and VES Techniques in the Northern Part of Bishkek -- Chapter 11: Designing Sustainable Futures: Interdisciplinary Science and Social Creativity -- Chapter 12: Water Reuse for Irrigation in Rural Areas in Japan: Implications/Insights for Central Asia and Afghanistan -- Chapter 13: Physics-Chemical Properties of the Kyzyl-Suu River and its tributaries -- Chapter 14: Environmental and Water Resources Management Study of Ghorband-Panjshir and Kunduz Rivers Basins, Afghanistan -- Chapter 15: Investigation of the High Mountain Vegetation Using Satellite Imagery, Kyrgyzstan -- Chapter 16: New Approaches and Advanced Methodology in Integrated Water Resources Management: Amu Darya River Basin -- Chapter 17: Investigation of the Various Aspects of the Kafirnigan River Basin, Tajikistan. .
    Abstract: The book provides a cross-sectoral, multi-scale assessment of development-directed investigations in the main rivers of wider Central Asia and Afghanistan. The book highlights the development of river systems, water reservoirs, ecosystems and risks as well as the impact of climate change on water resources in Central Asian countries and Afghanistan. It provides information on the genesis of river basins, physical and chemical properties of water in rivers, and the hydrological regimes of the rivers of Central Asia and Afghanistan. The book is useful for scientists and researchers whose work focuses on rivers and the use of water resources, irrigation, ecosystems, risks, water supply, climate change and remote sensing, as well as for students and planners, administrations and other stakeholders in the water sector.
    Type of Medium: Online Resource
    Pages: VII, 193 p. 91 illus., 77 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030683375
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-68337-5
    DOI: 10.1007/978-3-030-68337-5
    DDC: 551.48
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    Hydrological Extremes : River Hydraulics and Irrigation Water Management (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Food security. ; Natural disasters. ; Environmental monitoring. ; Sustainability. ; Water. ; Food Security. ; Natural Hazards. ; Environmental Monitoring. ; Sustainability.
    Description / Table of Contents: Intelligent Irrigation Water Management -- River Hydraulics -- Assessment and Monitoring of Hydrological Extremes -- Future Scenarios.
    Abstract: This book presents quality technical papers representing the recent developments in the field of hydrological modeling, water management and water governance including practical applications. The content covers multifarious aspects of hydrology and water resources. It includes an application of the Hydrologic Modelling System (HEC-HMS) which has been successfully demonstrated for assessment of floods. The authors suggest an approach for the mitigation of cyclone disaster through a case study of the Phailin cyclone, whilst considering mitigating pluvial flooding, developing suitable management strategies. The book includes chapters discussing the detrended fluctuation analysis which is carried out for multifractal description of droughts. Drought characteristics are analyzed, and drought indices evolved for drought preparedness/management. The use of science in community planning under changing climate is also studied and discussed. The authors present and experimental study wherein hydraulic coefficients are calibrated by using vertical orifice. A cross flow hybrid hydrokinetic turbine is also evaluated for performance, and high head regulating radial gate designed and studied its sensitivity. This book will appeal to researchers, field practitioners, NGO and other Governmental as well as private water practitioners .
    Type of Medium: Online Resource
    Pages: XII, 446 p. 262 illus., 230 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030591489
    Series Statement: Water Science and Technology Library, 97
    URL: https://doi.org/10.1007/978-3-030-59148-9
    DOI: 10.1007/978-3-030-59148-9
    DDC: 551.48
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    Water Management and Water Governance : Hydrological Modeling (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Geographic information systems. ; Ecology Methodology. ; Environmental sciences Social aspects. ; Water. ; Geographical Information System. ; Ecological Modelling. ; Environmental Social Sciences.
    Description / Table of Contents: 1. Application of RS and GIS in Watershed Management -- 2. Application of RS and GIS in Agricultural Water Management -- 3. Hydrological Modeling -- 4. Intelligent Water Management -- 5. Water Governance.
    Abstract: This book focusses on hydrological modeling, water management, and water governance. It covers the applications of remote sensing and GIS tools and techniques for land use and land cover classifications, estimation of precipitation, evaluation of morphological changes, and monitoring of soil moisture variability. Moreover, remote sensing and GIS techniques have been applied for crop mapping to assess cropping patterns, computation of reference crop evapotranspiration, and crop coefficient. Hydrological modeling studies have been carried out to address various issues in the water sector. MODFLOW model was successfully applied for groundwater modeling and groundwater recharge estimation. Runoff modeling has been carried out to simulate the snowmelt runoff together with the rainfall and sub-surface flow contributions for snow-fed basins. A study has been included, which predicts the impact of the land use and land cover on stream flow. Various problems in the water sector have been addressed employing hydrological models such as SWAT, ArcSWAT, and VIC. An experimental study has been presented wherein the laboratory performance of rainfall simulator has been evaluated. Hydrological modeling studies involving modifications in the curve number methodology for simulation of floods and sediment load have also been presented. This book is useful for academicians, water practitioners, scientists, water managers, environmentalists, and administrators, NGOs, researchers, and students who are involved in water management with the focus on hydrological modeling, water management, and water governance.. .
    Type of Medium: Online Resource
    Pages: XI, 550 p. 265 illus., 231 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030580513
    Series Statement: Water Science and Technology Library, 96
    URL: https://doi.org/10.1007/978-3-030-58051-3
    DOI: 10.1007/978-3-030-58051-3
    DDC: 551.48
    Language: English
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  • 45
    Online Resource
    Online Resource
    The Worth of Water : Designing Climate Resilient Rainwater Harvesting Systems (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Pollution. ; Environmental policy. ; Sociology. ; Environmental economics. ; Water. ; Pollution. ; Environmental Policy. ; Sociology. ; Environmental Economics.
    Description / Table of Contents: Chapter1: The circular economy of water (CEW) -- Chapter2: Water treatment: pollution removal mechanisms in the rainwater harvesting process -- Chapter3: Supply & demand: multiple waters for multiple purposes and multiple uses -- Chapter4: The components of a rainwater harvesting system: modular, standardised, plug and play -- Chapter5: Climate resilient RWH: a technological portfolio -- Chapter6: Rainwater harvesting design -- Chapter7: The economics of rainwater harvesting -- Chapter8: Rainwater harvesting and the sustainable development goals (SDG's).
    Abstract: There is no more fundamental substance to life on earth than water. Ninety nine percent of all human molecules are water molecules. Three quarter of the earth’s surface is covered by either saltwater or freshwater, yet millions face a daily struggle to access enough water for survival. The effects of ongoing climate change have expanded the water crisis to areas previously considered water secure. This book addresses the role rainwater harvesting (rwh) can play in developing a resilient water infrastructure that will prove adaptive to climate change and its implications. The book features three sections. The first section presents the concepts underpinning a new approach to water infrastructure. The term “the worth of water” was developed to reflect the importance of the social life of water. This encompasses all human relationships with water including the social, cultural, hydrological, political, economic, technical and spiritual. A technology portfolio showcasing the worth of water from the qanats of the ancient world to the modern rain cities is presented. Other concepts discussed include the circular economy of water and the concept of multiple waters for multiple users of multiple qualities. Water and its properties are a function of its peculiar molecular structure and this is illustrated in the book. Rainwater harvesting is considered by the authors as containing an inherent treatment train which functions as a complex water treatment system. The physical, chemical and biological removal mechanisms that form an inherent part of the rwh system are discussed. Part two presents a new rwh design methodology together with design templates and worked examples for the hydraulic and economic analysis of rwh systems. A state-of-the-art literature review of the potential health implications of utilizing rwh is also presented. The final section of the book discusses how rwh can play a vital role in contributing to achieving the sustainable development goals and to living within the planetary boundaries.
    Type of Medium: Online Resource
    Pages: XXIV, 206 p. 199 illus., 193 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030506056
    URL: https://doi.org/10.1007/978-3-030-50605-6
    DOI: 10.1007/978-3-030-50605-6
    DDC: 551.48
    Language: English
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  • 46
    Online Resource
    Online Resource
    The Realities of Adaptive Groundwater Management : Chino Basin, California (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental management. ; Political science. ; Political planning. ; Environmental sciences Social aspects. ; Water. ; Environmental Management. ; Governance and Government. ; Public Policy. ; Environmental Social Sciences.
    Description / Table of Contents: Chapter 1. Introduction: The Realities of Adaptive Management -- Chapter 2. The Natural Physical System of Chino Basin -- Chapter 3. The Development of Water Supplies and Water Conservation in Chino Basin -- Chapter 4. Upstream-Downstream Conflicts, 1930-1960 -- Chapter 5. Setting the Stage for a Chino Basin Management Program: Changes in Water Use, and the Third Santa Ana River Litigation, 1960-1969 -- Chapter 6. The Chino Basin Adjudication -- Chapter 7. The Governance Structure for Chino Basin under the Judgment -- Chapter 8. Water Management in the Basin during the First 20 Years under the Judgment -- Chapter 9. Turbulence: The 1990s in Chino Basin -- Chapter 10. Reconstituting Chino Basin Governance and Management -- Chapter 11. Adapting to Social and Economic Change -- Chapter 12. Adapting to and with the Neighbors -- Chapter 13. Adapting to the Changing Realities of Water Supply -- Chapter 14. Adapting to Water Quality Problems and Priorities -- Chapter 15. Resetting the Safe Yield and Reappointing the Watermaster -- Chapter 16. Looking Ahead: The Reality of Continual Adaptation -- Chapter 17. Lessons from Chino Basin for Adaptive Groundwater Management [note: includes section on California’s Sustainable Groundwater Management Act (SGMA)].
    Abstract: This book has three primary objectives. The first objective is to provide scholars with a more realistic view of adaptive management, without arguing against adaptive management. Adaptive management is necessary as well as desirable, but it is not easy, and demonstrating that through the Chino Basin experience is an important goal. The second objective is to provide practitioners with encouraging yet cautionary lessons about the challenges and benefits of an adaptive approach – in similar fashion as the first objective, the goal here is to endorse the adaptive approach but in a clear-eyed manner that clarifies how hard it is and how much it requires. A third objective is to show all audiences that resource governance systems can fail, change, and succeed. There is no such thing as an ideal institutional design that is guaranteed to work; rather, making institutional arrangements work entails learning and adjustment when they begin to show problems as they inevitably will. .
    Type of Medium: Online Resource
    Pages: XX, 288 p. 19 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030637231
    Series Statement: Global Issues in Water Policy, 27
    URL: https://doi.org/10.1007/978-3-030-63723-1
    DOI: 10.1007/978-3-030-63723-1
    DDC: 551.48
    Language: English
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  • 47
    Online Resource
    Online Resource
    Marine Nitrogen Fixation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Biogeography. ; Microbiology. ; Freshwater ecology. ; Marine ecology. ; Water. ; Biogeosciences. ; Microbiology. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Chapter1: Nitrogen Fixation in the Marine Environment -- Chapter2: Fundamentals of N2 Fixation -- Chapter3: History of Research on Marine N2 Fixation -- Chapter4: Microorganisms and Habitats -- Chapter5: Measurements of Organism Abundances and Activities -- Chapter6: Factors Controlling N2 Fixation -- Chapter7: Biogeography of N2 Fixation in the Surface Ocean -- Chapter8: N2 Fixation in Ocean Basins -- Chapter9: Marine N2 Fixation, Global Change and the Future -- Chapter10: Summary and Conclusions.
    Abstract: This book aims to serve as a centralized reference document for students and researchers interested in aspects of marine nitrogen fixation. Although nitrogen is a critical element in both terrestrial and aquatic productivity, and nitrogen fixation is a key process that balances losses due to denitrification in both environments, most resources on the subject focuses on the biochemistry and microbiology of such processes and the organisms involved in the terrestrial environment on symbiosis in terrestrial systems, or on largely ecological aspects in the marine environment. This book is intended to provide an overview of N2 fixation research for marine researchers, while providing a reference on marine research for researchers in other fields, including terrestrial N2 fixation. This book bridges this knowledge gap for both specialists and non-experts, and provides an in-depth overview of the important aspects of nitrogen fixation as it relates to the marine environment. This resource will be useful for researchers in the specialized field, but also useful for scientists in other disciplines who are interested in the topic. It would provide a possible text for upper division classes or graduate seminars.
    Type of Medium: Online Resource
    Pages: XV, 186 p. 36 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030677466
    URL: https://doi.org/10.1007/978-3-030-67746-6
    DOI: 10.1007/978-3-030-67746-6
    DDC: 551.48
    Language: English
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  • 48
    Online Resource
    Online Resource
    Heavy Metals in Scleractinian Corals (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Environmental chemistry. ; Environment. ; Water. ; Environmental Chemistry. ; Environmental Sciences.
    Description / Table of Contents: Heavy Metals - An Overview -- Coral Reef Ecosystems -- The Use of Scleractinian Corals for Heavy Metal Studies -- Analytical Techniques Used for Heavy Metal Analysis in Corals.
    Abstract: This book provides an in-depth review of heavy metals in corals, describing the sources of heavy metals in the marine environment and their effect on corals. It is designed to serve as a unique reference for upcoming marine researchers and chemists, advanced undergraduate and postgraduate students as well as those interested in marine pollution with respect to heavy metals. The book explains the basics as well as the state-of-the-art regarding heavy metals and corals and is engaging and clearly written and narrated, providing readers with the fundamental tools about the subject matter that they need in their specific fields. It allows readers to understand and appreciate the interactions between the atmosphere, ocean, and the geosphere. Detailed reference is included for the benefit of the reader. The specific objectives of this book are (i) to inform/educate the reader about persistent pollutants such as heavy metals, (ii) to identify sources of heavy metals in the marine environment, (iii) to inform about route of exposure and uptake of the heavy metal pollutants by corals, (iv) to elaborate about the effect of heavy metal pollutants on the coral reef ecosystems, (v) to discuss the ways in which heavy metal regulation occurs in corals, (vi) to impact current knowledge regarding heavy metals in the marine environment, and (vii) to briefly show chemical analysis and instrumentation for analyzing heavy metals.
    Type of Medium: Online Resource
    Pages: X, 90 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030736132
    Series Statement: SpringerBriefs in Earth Sciences,
    URL: https://doi.org/10.1007/978-3-030-73613-2
    DOI: 10.1007/978-3-030-73613-2
    DDC: 551.48
    Language: English
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  • 49
    Online Resource
    Online Resource
    Climate Change and Groundwater: Planning and Adaptations for a Changing and Uncertain Future : WSP Methods in Water Resources Evaluation Series No. 6 (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Water. ; Hydrology. ; Physical geography. ; Natural disasters. ; Water. ; Earth System Sciences. ; Natural Hazards.
    Description / Table of Contents: 1. Introduction to Climate Change and Groundwater -- 2. Climate and Groundwater Primer -- 3. Historical Evidence for Anthropogenic Climate Change and Climate Modeling Basics -- 4. Intergovernmental Panel on Climate Change and Global Climate Change Projections -- 5. Modeling of Climate Change and Aquifer Recharge and Water Levels -- 6. Sea Level Rise and Groundwater -- 7. Climate Change and Small Islands -- 8. Groundwater Related Impacts of Climate Change on Infrastructure -- 9. Adaptation and Resilience Concepts -- 10. Adaptation Options -- 11. Conjunctive Use -- 12. Climate Change Adaptation - Water Management Decision Making Process -- 13. Regional Hydrological Impacts to Climate Changes and Adaptation Actions and Options -- 14. Applied Climate Change Assessment and Adaptation.
    Abstract: This book attempts to bridge the gap between the climate change research and decision-making communities by exploring the impacts of climate change on groundwater from a more applied perspective. Global climate change will impact groundwater demands, quality, and available supplies, and rising sea level may cause water tables to rise, inundating low-lying coastal areas. Groundwater will increasingly be needed to perform a stabilization role in mitigating fluctuations in the supply of surface waters, serving as a buffer against droughts. Climate change has become a frequent subject in the mass media, and the academic literature on the subject is now enormous. An impediment to climate change adaptation with respect to water is a poor link between the climate change research community and the actual decision-makers responsible for water supply planning. Key issues explored are methods for evaluating potential impacts on climate change on local groundwater systems, the adaptation of decision-making process, and how climate change adaptation can be mainstreamed into the water supply planning.
    Type of Medium: Online Resource
    Pages: XV, 350 p. 54 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030668136
    Series Statement: Springer Hydrogeology,
    URL: https://doi.org/10.1007/978-3-030-66813-6
    DOI: 10.1007/978-3-030-66813-6
    DDC: 551.48
    Language: English
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