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  • Books  (221)
  • Cham :Springer International Publishing :  (221)
  • 551  (130)
  • 571.96  (46)
  • 571.978  (45)
  • 1
    Online Resource
    Online Resource
    Notch Signaling in Embryology and Cancer : Molecular Biology of Notch Signaling (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Embryology. ; Cancer Biology. ; Cell Biology. ; Embryology.
    Description / Table of Contents: Challenge and Promise: A Snap-Shot on the Molecular Biology of Notch Signaling -- Overview of Basic Mechanisms of Notch Signaling in Development and Disease -- Ligand-induced cis-inhibition of Notch signaling: the role of an extracellular region of Serrate -- Phosphorylation and proteolytic cleavage of Notch in canonical and non-canonical Notch signaling -- Maheshvara a conserved RNA helicase regulates Notch signaling in Drosophila melanogaster -- Molecular Regulation of Notch Signaling by Gremlin -- Regulation of Notch Signaling in Drosophila melanogaster: the role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex -- Interaction of Long Non-Coding RNAs and Notch Signaling: Implications for Tissue Homeostasis Loss -- Insulin–dependent non-canonical activation of Notch in Drosophila: a story of Notch-induced muscle stem cells proliferation -- Molecular mechanisms of Notch signaling in lymphoid cell lineages development: NF-κB and beyond -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch’s flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway’s role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books – Notch Signaling in Embryology and Notch Signaling in Cancer – this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.
    Type of Medium: Online Resource
    Pages: XIII, 172 p. 32 illus., 31 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030364229
    Series Statement: Advances in Experimental Medicine and Biology, 1227
    URL: https://doi.org/10.1007/978-3-030-36422-9
    DOI: 10.1007/978-3-030-36422-9
    DDC: 571.978
    Language: English
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  • 2
    Online Resource
    Online Resource
    Tumor Microenvironment : Molecular Players – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cytology. ; Internal medicine. ; Cancer Microenvironment. ; Cancer Biology. ; Cell Biology. ; Internal Medicine.
    Description / Table of Contents: MicroRNAs in the tumor microenvironment -- The Impact of Estrogen in the Tumor Microenvironment -- The non-bone related role of RANK/RANKL signaling in cancer -- Modulation of Cancer Cell Growth and Progression by Caveolin-1 in the Tumor Microenvironment -- Exosomes: Novel Players of Therapy Resistance in Neuroblastoma -- COX-2 Signaling in the Tumor Microenvironment -- Renin–angiotensin system in the tumor microenvironment -- Stem cell secreted factors in the tumor microenvironment -- Tight interplay between therapeutic monoclonal antibodies and the tumor microenvironment in cancer therapy -- Tumor Microenvironment & Nitric Oxide: Concepts and Mechanisms -- Index.
    Abstract: This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including MicroRNAs, estrogen, Caveolin-1, Nitric Oxide, RANK/RANKL signaling, , COX-2 Signaling, Renin–angiotensin system, and more. Taken alongside its companion volumes, Tumor Microenvironment: Molecular Players – Part B updates us on what we know about the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIV, 162 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030502249
    Series Statement: Advances in Experimental Medicine and Biology, 1277
    URL: https://doi.org/10.1007/978-3-030-50224-9
    DOI: 10.1007/978-3-030-50224-9
    DDC: 571.978
    Language: English
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  • 3
    Online Resource
    Online Resource
    Basic and Clinical Immunology by Names : From the Biblical Time Until the Present (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medicine History. ; Medicine Research. ; Biology Research. ; Immunology. ; History of Medicine. ; Biomedical Research.
    Description / Table of Contents: A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Z.
    Abstract: Hundreds of eponyms are used within the field of immunology—Petri dish, Crohn’s disease, Bence Jones protein, Kupffer cells, Freund's adjuvant, Ouchterlony immunodiffusion, to name just a few—but most of us don't know much about the individuals who gave their names to these terms. Where were they born and educated, what other accomplishments are they credited with, why has history chosen to remember them, or not? This book presents the first comprehensive collection of immunologic eponyms, and through them tells the story of this fascinating field, from its earliest beginnings to present day. Organized by surname and meticulously cross-referenced and indexed, this book offers historical anecdotes and little-known facts which scientists, clinicians, students, and general readers will find captivating and memorable. A one-of-a-kind introduction to immunology that serves as both a history lesson and current reference on the diseases, treatments, and individuals who have been crucial to this field.
    Type of Medium: Online Resource
    Pages: XXVIII, 405 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031145292
    URL: https://doi.org/10.1007/978-3-031-14529-2
    DOI: 10.1007/978-3-031-14529-2
    DDC: 571.96
    Language: English
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  • 4
    Online Resource
    Online Resource
    Tumor Microenvironment : Signaling Pathways – Part B (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030471897
    Series Statement: Advances in Experimental Medicine and Biology, 1270
    URL: https://doi.org/10.1007/978-3-030-47189-7
    DOI: 10.1007/978-3-030-47189-7
    DDC: 571.978
    Language: English
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  • 5
    Online Resource
    Online Resource
    The Systemic Effects of Advanced Cancer : A Textbook on Cancer-Associated Cachexia (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Oncology. ; Immunology. ; Metastasis. ; Cytology. ; Cancer Biology. ; Oncology. ; Immunology. ; Metastasis. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Systemic View of Metastatic Disease: Inter-organ Crosstalk and Therapeutic Implications -- Part I. Systemic Regulation in Metastatic Disease -- Chapter 2. Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles -- Chapter 3. Bone Metastasis: Systemic Regulation and Impact on Host -- Chapter 4. Targeting Metastatic Disease: Challenges and New Opportunities -- Part II. Cachexia: A Debilitating Systemic Effect of Cancer -- Chapter 5. Signaling Pathways That Promote Muscle Catabolism in Cachexia -- Chapter 6. The Role of Interleukin-6 Cytokines in Cancer Cachexia -- Chapter 7. NF-kB Signaling in the Macroenvironment of Cancer Cachexia -- Part III. Therapy-induced Muscle Wasting -- Chapter 8. Therapy-induced Toxicities Associated with the Onset of Cachexia -- Chapter 9. Bone-muscle Crosstalk in Advanced Cancer and Chemotherapy -- Part IV. Preventing and Targeting Cachexia in Cancer -- Chapter 10. New Developments in Targeting Cancer Cachexia -- Chapter 11. Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer.
    Abstract: This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-kB, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology.
    Type of Medium: Online Resource
    Pages: VI, 203 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031095184
    URL: https://doi.org/10.1007/978-3-031-09518-4
    DOI: 10.1007/978-3-031-09518-4
    DDC: 571.978
    Language: English
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  • 6
    Online Resource
    Online Resource
    Amino Acids in Nutrition and Health : Amino acids in systems function and health (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Preface -- Amino acids in intestinal physiology and health -- Amino acid metabolism in the liver: nutritional and physiological significance -- Amino acids in circulatory function and health -- Epithelial dysfunction in lung diseases: effects of amino acids and potential mechanisms -- Amino acid metabolism in the kidneys: nutritional and physiological significance -- Amino acids in health and endocrine function -- Amino Acids in Reproductive Nutrition and Health -- Impacts of amino acids on the intestinal defensive system -- Maternal nutrient restriction and skeletal muscle development: Consequences for postnatal health -- Metabolism of amino acids in the brain and their roles in regulating food intake -- Metabolism and functions of amino acids in the skin -- Metabolism and functions of amino acids in sense organs. .
    Abstract: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in all the systems of humans and other animals (including livestock, poultry, companion animals, and fish). It enables readers to understand the crucial roles of amino acids and their metabolites in the health and diseases of the circulatory, digestive, endocrine, immune, muscular, nervous, reproductive, respiratory, skeletal, and urinary systems, as well as the sense organs (eyes, ears, nose, skin, and tongue). Readers will learn that amino acids are not only the building blocks of protein, but are also signalling molecules, as well as regulators of gene expression, metabolic processes and developmental changes in the body. This knowledge will guide nutritional practices to improve the growth, development and health of humans and other animals, as well as prevent and treat chronic (e.g., obesity, diabetes, and cardiovascular disorders) and infectious (e.g., bacterial, fungal, parasite, and viral) diseases. Editor of this volume is an internationally recognized expert in nutritional biochemistry. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals as well as undergraduate and graduate students in animal science, biochemistry, biomedical engineering, biology, human medicine, food science, kinesiology, nursing, nutrition, pharmacology, physiology, toxicology, veterinary medicine, and other related disciplines. In addition, all chapters provide general and specific references to amino acids in systems health for researchers and practitioners in biomedicine, animal and plant agriculture, and aquaculture, and for government policy makers.
    Type of Medium: Online Resource
    Pages: VI, 220 p. 36 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030453282
    Series Statement: Advances in Experimental Medicine and Biology, 1265
    URL: https://doi.org/10.1007/978-3-030-45328-2
    DOI: 10.1007/978-3-030-45328-2
    DDC: 571.96
    Language: English
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  • 7
    Online Resource
    Online Resource
    Cancer Biology: How Science Works (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Genetics. ; Molecular biology. ; Cancer Biology. ; Genetics and Genomics. ; Molecular Biology.
    Description / Table of Contents: 1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
    Abstract: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
    Type of Medium: Online Resource
    Pages: XVII, 167 p. 72 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030756994
    URL: https://doi.org/10.1007/978-3-030-75699-4
    DOI: 10.1007/978-3-030-75699-4
    DDC: 571.978
    Language: English
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  • 8
    Online Resource
    Online Resource
    Tumor Microenvironment : Extracellular Matrix Components – Part A (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: The tumor microenvironment: focus on extracellular matrix -- Keratan Sulphate in the Tumour Environment -- Hyaluronan in the tumor microenvironment -- Fibronectin in the tumor microenvironment -- Matrix metalloproteinases role in tumor microenvironment -- Flipping the Molecular Switch: Influence of Perlecan and its Modifiers in the Tumor Microenvironment -- Heparan sulfate in the tumor microenvironment -- The role of Glypican-1 in the tumour microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components with the tumor during cancer development. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include heparan sulphate, hyaluronan, fibronectin, perlecan, glypican, matrix metalloproteinases, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part A updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newer generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book will be an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapter authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.
    Type of Medium: Online Resource
    Pages: XI, 181 p. 29 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030401467
    Series Statement: Advances in Experimental Medicine and Biology, 1245
    URL: https://doi.org/10.1007/978-3-030-40146-7
    DOI: 10.1007/978-3-030-40146-7
    DDC: 571.978
    Language: English
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  • 9
    Online Resource
    Online Resource
    Current Advances in the Science of Osteosarcoma : Research Perspectives: Tumor Biology, Organ Microenvironment, Potential New Therapeutic Targets, and Canine Models (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Medical microbiology. ; Cytology. ; Pediatrics. ; Cancer Biology. ; Medical Microbiology. ; Cell Biology. ; Pediatrics.
    Description / Table of Contents: The genomic complexity of osteosarcoma and its implication for preclinical and clinical targeted therapies -- Genomics and the Immune Landscape of Osteosarcoma -- RECQ DNA Helicases and Osteosarcoma -- Targeting the Cancer Epigenome with Histone Deacetylase Inhibitors in Osteosarcoma -- Oncolytic viruses and their potential as a therapeutic opportunity in Osteosarcoma -- Applying Osteosarcoma Immunology to Understand Disease Progression and Assess immunotherapeutic Response -- Targetable intercellular signaling pathways facilitate lung colonization in osteosarcoma -- Wnt Signaling in Osteosarcoma -- Receptor Tyrosine Kinases in Osteosarcoma: 2019 update -- The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets -- Autophagy in OS -- Fas signaling as a potential target for the treatment of osteosarcoma metastasis in the lungs -- Exosomes: Dynamic Mediators of Extracellular Communication in the Tumor Microenvironment -- Comparative Immunology and Immunotherapy of Canine Osteosarcoma -- Index.
    Abstract: This thoroughly revised second edition is an up-to-date overview of the new advances in the knowledge of the basic science in sarcoma and osteosarcoma. It features detailed, in-depth discussions of microRNAs in osteosarcoma, historical perspectives of chemotherapy in the treatment of the disease, tumor targeted IL12 therapy and HER2 targeted therapy, the role of enhancer elements in regulating the prometastatic transcriptional program and more. Further, this essential volume also includes new insights on Wnt signaling in osteosarcoma, the role of genomics, genetically modified T-cell therapy, liquid biopsy, oncolytic viruses, immunophenotyping, receptor tyrosine kinases and epigenetic-focused approaches for treatment of osteosarcoma metastases, as well as thoughts on the current standard of treatment for patients suffering from these cancers. In the years since the previous edition, there have been numerous new developments in this rapidly changing field; this new edition is both timely and urgently needed. When taken together these companion volumes, Current Clinical (Book 1) and Scientific (Book 2) Advances in Osteosarcoma, are a timely and urgently needed guide for laboratory investigators and clinical oncologists.
    Type of Medium: Online Resource
    Pages: XIII, 233 p. 34 illus., 23 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030430856
    Series Statement: Advances in Experimental Medicine and Biology, 1258
    URL: https://doi.org/10.1007/978-3-030-43085-6
    DOI: 10.1007/978-3-030-43085-6
    DDC: 571.978
    Language: English
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  • 10
    Online Resource
    Online Resource
    Advanced Concepts in Human Immunology: Prospects for Disease Control (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Pharmacology. ; Diseases. ; Cancer. ; Immunology. ; Pharmacology. ; Diseases. ; Cancer Biology.
    Description / Table of Contents: 1. Human Chronic Viruses: Pathogenesis, host response, and treatment -- 2. Defining the Role of Immunoproteomics in Human Immunotherapy -- 3. Microbiome and Cellular Players in Type 1 Diabetes: from Pathogenesis to Protection -- 4. Immune Mechanisms, Pathology, and Management of Allergic Ocular Diseases -- 5. Dendritic Cell-regulated T Cell Immunity and Tolerance against Acute Myeloid Leukemia -- 6. Perspectives on the Role of T cell Negative Immune Checkpoint Receptors in Health and Disease -- 7. Neuroprotective Immunity for Neurodegenerative and Neuroinfectious Diseases -- 8. Polycystic Ovary Syndrome: An overview of a complex, heterogeneous genetic condition.
    Abstract: This book highlights information derived primarily from clinical samples, with particular reference to theoretical and scientific aspects of the human immune system. This text will focus on topics that range from host-pathogen interactions in infectious disease to host immune response in cancer, allergic diseases, neuroinflammatory diseases, and autoimmune disorders. The reader will also have a well-rounded understanding of the behavior of the immune system with particular emphasis on the role of immunoproteomics in immunotherapy, neuroprotective immunity for neurodegenerative and neuroinfectious disease, leukemia-associated dendritic cell induction of adaptive immunity dysregulation, and the role of immune checkpoint inhibitors in cancer, infection, as well as neuroinflammation. Taken together, the contents of this book are intended for both clinicians and researchers in academia and industry.
    Type of Medium: Online Resource
    Pages: XVIII, 403 p. 16 illus., 5 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339463
    URL: https://doi.org/10.1007/978-3-030-33946-3
    DOI: 10.1007/978-3-030-33946-3
    DDC: 571.96
    Language: English
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  • 11
    Online Resource
    Online Resource
    Outbreak in the Village : A Family Doctor's Lifetime Study of Whooping Cough (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Life sciences. ; Pharmacology. ; Medical sciences. ; Medicine History. ; Public health. ; Immunology. ; Life Sciences. ; Pharmacology. ; Health Sciences. ; History of Medicine. ; Public Health.
    Description / Table of Contents: 1. Introduction -- 2. From Africa to England -- 3. The children's clinic at Keyworth -- 4. Whooping cough vaccine -- 5. 1977-79: The first outbreak of whooping cough -- 6. Does the vaccine work? -- 7. 1981: Whooping cough vaccine is very rarely harmful -- 8. 1981-83: The second outbreak. How many cases are there really? -- 9.1985-87: The third outbreak. The search for subclinical infection -- 10. Does the effectiveness of the vaccine wear off? -- 11. 1988: Trying to raise the uptake of pertussis vaccine -- 12. 1989-91: The fourth outbreak. The natural history of whooping cough -- 13. 1990's: Whooping cough fades away but new diagnostic tests emerge -- 14. 2000: Whoopingcough.net. Overcoming diagnostic paralysis -- 15. The early noughties: The new tests aid the rediscovery of whooping cough -- 16. Late noughties: "Resurgence" of whooping cough in the USA and Australia puts the UK on alert -- 17. 2012: Whooping cough diagnoses peak in the UK but remain unchanged in Keyworth -- 18. What lies ahead? -- 19. Epilogue -- Appendix.
    Abstract: Outbreak in the Village is a fascinating account of the personal and professional journey of Dr. Doug Jenkinson, physician and researcher. Over the course of four decades in practice, Jenkinson traces the reemergence of whooping cough in the developed world, using his practice in the idyllic English countryside as a clinical control group. Keeping meticulous notes and indulging an itch to investigate, he explores one of history's most enigmatic and pervasive diseases. Jenkinson relates the tale of his life's work amid winsome anecdotes, relevant history, and practical advice. Told in an amiable, engaging voice with an expert balance of levity and earnestness, this story will charm casual readers interested in medical history and memoir, as well as doctors and researchers who identify with the experiences and may benefit from the research and techniques employed. Readers will find themselves in the examination room beside Jenkinson as the investigation unfolds, learning about the nature of the illness and the sweeping detrimental effects of an anti-vaccination campaign. An intriguing memoir about a mysterious illness, a public health failure, and one doctor's quest for clarity, Outbreak in the Village is a tale of perseverance and objectivity sure to delight and inform. .
    Type of Medium: Online Resource
    Pages: XXIII, 158 p. 63 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030454852
    Series Statement: Springer Biographies,
    URL: https://doi.org/10.1007/978-3-030-45485-2
    DOI: 10.1007/978-3-030-45485-2
    DDC: 571.96
    Language: English
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  • 12
    Online Resource
    Online Resource
    Heparanase : From Basic Research to Clinical Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Oncology. ; Medicine Research. ; Biology Research. ; Cancer Biology. ; Oncology. ; Biomedical Research.
    Description / Table of Contents: Section 1: Historical Background -- Chapter 1: Mast cell/platelet heparanase/Heparan sulfate biosynthesis and turnover -- Chapter 2: gene cloning/overview -- Chapter 3: gene cloning/melanoma metastasis -- Chapter 4: gene cloning/cancer/immune system -- Chapter 5: heparin/HS modifying enzymes -- Section 2: Crystal Structure/substrate specificity/gene regulation -- Chapter 6: crystal structure -- Chapter 7: molecular dynamics, KKDC peptide -- Chapter 8: Biochemistry/active site -- Chapter 9: substrate specificity -- Chapter 10: gene regulation, promoter/Egr1/methylation -- Chapter 11: SNPs -- polymorphism -- Chapter 12: Splice variants -- Section 3: Cell & tumor biology (general functions & mode of action) -- Chapter 13: Exosomes/heparan sulfate/heparanse -- Chapter 14: Exosomes/drug resistance -- Chapter 15: Nuclear heparanse/transcriptional activity -- Chapter 16: Non-Enzymatic functions/Signal transduction/cellular trafficking/autophagy -- Chapter 17: Heparan sulfate/stem cells/inflammation -- Chapter 18: Danger signals/HS/platelet heparanse -- Chapter 19: Heparanse/Intergrins/Melanoma -- Section 3: Immune Cells/Immnuno-Modulation -- Chapter 20: Heparain. Heparanse and Selectins in Cancer Metastasis and Inflamation --- Chapter 21: Trans-Endithelial Migration, Lymphocytes, Neutrophils/T-cells --Chapter 22: Macrophages, dendritic cells, autoimmunity -- Chapter 23: Macrophages, Heparanse and the tumor microenvironment, neutralizing antibodies -- Chapter 24: NK Cells -- Section 4: Cancer (heparanse in specific types of cancer) -- Chapter 25: Myeloma, inhbition, drug resistance -- Chapter 26: Breast Cancer/Pancreatic Cancer/Cancer and Inflammation -- Chapter 27: Brain Metastasis/MIR-1258 -- Chapter 28: Gastric cancer/immunization -- Chapter 29: Head and Neck Cancer -- Chapter 30: Glioma -- Chapter 31: Sarcoma -- Section 5: Inhibitors/clinical trails/cancer -- Chapter 32: Chemistry/synthesis of heparanse inhibitors PI-88, PG -- Chapter 33: PG series/biology/Tumor models and clinical trial -- Chapter 34:Chemically modified heparins/Heparin mimetics -- Chapter 35: Medicinal Chemistry (Ronesparstat/small molecules/clinical trials) - Section 6: Other indications/diseases -- Chapter 36: IBD/inflammation and cancer/diabetes/obesity -- Chapter 37: Immune Diabetes -- Chapter 38 Inflammation, Sepsis/Amyloidosis -- Chapter 39: Kidney dysfunction -- Chapter 40: Fibrosis -- Chapter 41: Viral infection -- Chapter 42: Cariomyocytes/Endothelial cell-cardiomyocyte crosstakl in diabetic cariomyopathy -- Chapter 43: Eye research -- Chapter 44: atheroscelerosis, nuclear localization -- Chapter 45: Yona Nadir (coagulation/tissue factor) -- Section 7: Heparanse-2 (Hpa2) -- Chapter 46: Hpa2 gene cloning -- Chapter 47: UFS -- urofacial syndrome/peripheral neuropathy -- Chapter 48: Hpa2: tumor suppressor.
    Abstract: Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.
    Type of Medium: Online Resource
    Pages: XVIII, 885 p. 168 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030345211
    Series Statement: Advances in Experimental Medicine and Biology, 1221
    URL: https://doi.org/10.1007/978-3-030-34521-1
    DOI: 10.1007/978-3-030-34521-1
    DDC: 571.978
    Language: English
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  • 13
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    Online Resource
    Molecular Immunology : How Science Works (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Autoimmunity. ; Inflammation. ; Immunogenetics. ; Tumors Immunological aspects. ; Immunology. ; Translational Immunology. ; Autoimmunity. ; Inflammation. ; Immunogenetics. ; Tumour Immunology.
    Description / Table of Contents: 1 Cells and tissues of the immune system -- 2 Innate immunity and inflammation -- 3 Adaptive immunity and antigen receptor diversity -- 4 B cell immunity: BCRs, antibodies and their effector functions -- 5 Antigen-presenting cells and the major histocompatibility complex -- 6 T cell immunity: TCRs and their effector functions -- 7 Immunity to bacterial pathogens and the microbiome -- 8 Immunity to viral pathogens and the virome -- 9 Tolerance and transplantation immunology -- 10 Immunological hypersensitivities: Allergy and autoimmunity -- 11 Cancer immunology.
    Abstract: This textbook aims to describe in a condensed form the essentials of molecular immunology behind bacterial infections, the microbiome, viral infections (such as influenza and COVID-19), organ transplantations, autoimmunity, allergy and tumor immunology. The book emphasizes the impact of immunology in maintaining our health and preventing disease. Our immune system protects us not only from severe consequences of infectious diseases and getting cancer, but is also able to harm us severely via sepsis, cytokine storms and anaphylactic shocks. Molecular understanding of immunology should allow the reader a more rational handling of common diseases, most of which are associated with chronic inflammation.
    Type of Medium: Online Resource
    Pages: XV, 219 p. 94 illus., 93 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031040252
    URL: https://doi.org/10.1007/978-3-031-04025-2
    DOI: 10.1007/978-3-031-04025-2
    DDC: 571.96
    Language: English
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  • 14
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    Online Resource
    Nrf2 and its Modulation in Inflammation (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Cytology. ; Molecular genetics. ; Stress (Physiology). ; Immunology. ; Cell Biology. ; Molecular Genetics. ; Cellular Stress.
    Description / Table of Contents: Chapter 1. Molecular mechanisms of Nrf2 in inflammation: Interactions between Nrf2 and inflammatory mediators -- Chapter 2. Nrf2 in immune responses during inflammation -- Chapter 3. Nrf2 and Nrf2-interacting network in respiratory inflammation and diseases -- Chapter 4. Nrf2 in the regulation of endothelial cell homeostasis during inflammation -- Chapter 5. The roles of Nrf2 in cardiovascular system and atherosclerosis -- Chapter 6. Nrf2 and inflammation-triggered carcinogenesis -- Chapter 7. Role of Nrf2 in oxidative and inflammatory processes in obesity and metabolic diseases -- Chapter 8. Modulators of Nrf2 Activation during Inflammation.
    Abstract: Nrf2, a transcription factor that mediates transcriptional responses to oxidative and xenobiotic stresses, plays a central role in cellular protection against internal or external toxins. Defects in Nrf2 and the relevant regulatory pathways are associated with a number of pathologies including inflammation,respiratory diseases, cardiovascular dysfunctions, metabolic syndrome and diabetes, neurodegeneration, and cancer. This book comprehensively reviews the up-to-date discoveries for the roles of Nrf2 in several human diseases in the context of inflammation. In particular, the molecular mechanisms that mediate the functions of Nrf2 and its interacting network in inflammation and pathogenesis are explicated. In addition, the research and therapeutic applications of Nrf2-targeting compounds in different diseases were summarized. This book is expected to be a valuable reference for worldwide researchers conducting both mechanistic and therapeutic studies of Nrf2 and relevant factors.
    Type of Medium: Online Resource
    Pages: IX, 205 p. 51 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030445997
    Series Statement: Progress in Inflammation Research, 85
    URL: https://doi.org/10.1007/978-3-030-44599-7
    DOI: 10.1007/978-3-030-44599-7
    DDC: 571.96
    Language: English
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  • 15
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    Online Resource
    Sunlight, Vitamin D and Skin Cancer (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Dermatology. ; Oncology. ; Cancer Biology. ; Dermatology. ; Oncology.
    Description / Table of Contents: Section I: Introduction -- Lessons learned from paleolithic models and evolution for human health: a snap shot on beneficial effects and risks of solar radiation -- Section II: UV-induced cutaneous synthesis of vitamin D and the physiologic consequences (I) -- Sunlight, UV-radiation, vitamin D and skin cancer: how much sunlight do we need? -- Section III: Solar radiation, Vitamin D and human health -- Vitamin D status and cancer incidence and mortality -- Vitamin D receptors polymorphisms and cancer -- On the relationship between sun exposure and all-cause mortality -- Lindqvist PG (2020) Women with greater sun exposure habits seem to be healthier and to live longer. Are these results in contrast to other research? No -- Section IV: Epidemiology of skin cancer -- Epidemiology of skin cancer and UV radiation – update 2019 -- Solar UV exposure and mortality from skin tumors: an update -- Solarium Use and Risk for Malignant Melanoma: many open questions,not the time to close the debate -- Section V: Photocarcinogenesis of skin cancer -- Molecular biology of basal and squamous cell carcinomas -- Human papillomaviruses and skin cancer -- The immune system and pathogenesis of melanoma and nonnmelanoma skin cancer -- Section VI: The relevance of the vitamin D endocrine system for skin cancer -- Protection from ultraviolet damage and photocarcinogenesis by vitamin D compounds -- The role of classical and novel forms of vitamin D in the pathogenesis and progression of non-melanoma skin cancers -- The Vitamin D Receptor as tumor suppressor in skin -- Cancer prevention in skin and other tissues via cross-talk between vitamin D- and p53- signalling -- Section VII: Prevention and Management of Skin Cancer -- Sunscreens in the United States: Current Status and Future Outlook -- A handful of sunscreen for whole body application -- Sunlight, vitamin D and Xeroderma pigmentosum -- Update: Solar UV-radiation, vitamin D and skin cancer surveillance in organ transplant recipients (OTRs) -- Section VIII: UV-induced cutaneous synthesis of vitamin D and the physiologic consequences – II. promise and outlook -- Ultraviolet exposure scenarios: balancing risks of erythema and cutaneous vitamin D synthesis -- The Paleolithic nutrition model in relation to ultraviolet light and vitamin D -- Index.
    Abstract: The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‑exposure to minimize the risks of developing vitamin D deficiency and skin cancer.
    Type of Medium: Online Resource
    Pages: XIV, 428 p. 83 illus., 28 illus. in color. , online resource.
    Edition: 3rd ed. 2020.
    ISBN: 9783030462277
    Series Statement: Advances in Experimental Medicine and Biology, 1268
    URL: https://doi.org/10.1007/978-3-030-46227-7
    DOI: 10.1007/978-3-030-46227-7
    DDC: 571.978
    Language: English
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  • 16
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    Online Resource
    Primary and Secondary Immunodeficiency : A Case-Based Guide to Evaluation and Management (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Rheumatology. ; Diseases. ; Hematology. ; Oncology. ; Primary care (Medicine). ; Immunology. ; Rheumatology. ; Diseases. ; Hematology. ; Oncology. ; Primary Care Medicine.
    Description / Table of Contents: Chapter 1. Overview of Immunodeficiency -- Part I. B-Lymphocyte Immunodeficiency -- Chapter 2. Common Variable Immunodeficiency, Hypogammaglobulinemia, and Specific Antibody Deficiency -- Chapter 3. Agammaglobulinemia -- Chapter 4. Class Switch Defects -- Chapter 5. Transient Immunodeficiency of Infancy -- Chapter 6. Selective Isotype Immunodeficiency -- Chapter 7. Common Variable Immunodeficiency Disorders-like Disorders -- Part II. T-Cell Immunodeficiency -- Chapter 8. Severe Combined Immunodeficiency -- Chapter 9. Idiopathic CD4 Lymphopenia -- Chapter 10. Hyper IgE Syndrome -- Chapter 11. Genetic Syndromes with Associated Immunodeficiencies -- Part III. Immune Dysregulation Syndromes -- Chapter 12. Autoimmune Lymphoproliferative Syndrome -- Chapter 13. Auto-inflammatory Syndromes -- Chapter 14. Immune Dysregulation Leading to Autoimmunity -- Chapter 15. Dendritic Cells in Primary Immunodeficiency -- Part IV. Innate Immune Defects -- Chapter 16. Congenital Neutropenia and Migration Defects -- Chapter 17. Chronic Granulomatous Disease -- Chapter 18. Primary Immunodeficiencies of Complement -- Chapter 19. Natural Killer Cell Defects -- Chapter 20. Mucocutaneous Candidiasis -- Part V. Secondary Immunodeficiency -- Chapter 21. Immunodeficiency Secondary to Malignancies and Biologics -- Chapter 22. Immunodeficiency Secondary to Prematurity, Pregnancy, and Aging -- Chapter 23. Vaccinations in Primary and Secondary Immunodeficiencies Including Asplenia.
    Abstract: This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases. Chapters begin with a comprehensive overview of immunodeficiencies to ground the reader in practical knowledge of the field and these complex conditions. Chapters cover B lymphocyte immunodeficiency, T cell immunodeficiency, immune dysregulation syndromes, and innate immune defects. They discuss a range of treatment options including gene therapy or bone marrow transplant. The book continues with a discussion on secondary immunodeficiencies and their treatment. Each chapter was written by authors with expertise related to different immunodeficiency disorders and provide a succinct overview of pathomechanisms, diagnosis, and treatment of a specific condition. Primary and Secondary Immunodeficiency will be an excellent resource for practicing allergists, hematologists, clinical immunologists, fellows, residents, and other clinicians who work with immunodeficiency patients.
    Type of Medium: Online Resource
    Pages: XI, 417 p. 34 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030571573
    URL: https://doi.org/10.1007/978-3-030-57157-3
    DOI: 10.1007/978-3-030-57157-3
    DDC: 571.96
    Language: English
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  • 17
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    Online Resource
    Lung Inflammation in Health and Disease, Volume II (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Human physiology. ; Medicine Research. ; Biology Research. ; Respiratory organs Diseases. ; Immunology. ; Human Physiology. ; Biomedical Research. ; Pneumology.
    Description / Table of Contents: 1. Can GPCRs be targeted to control inflammation in asthma? -- 2. Cellular and molecular processes in pulmonary hypertension -- 3. INFLAMMATORY PATHWAYS IN SARCOIDOSIS -- 4. Innate Immune Responses and Pulmonary Diseases -- 5. Interstitial Lung Disease associated with Connective Tissue Diseases -- 6. Molecular mechanisms of vascular damage during lung injury -- 7. Neurotrophin Regulation and Signaling in Airway Smooth Muscle -- 8. Novel Thoracic MRI approaches for the assessment of pulmonary physiology and inflammation -- 9. Overview on Interactive Role of Inflammation, Reactive Oxygen Species and Calcium signaling in Asthma, COPD and Pulmonary Hypertension -- 10. Protein S-palmitoylation and lung diseases -- 11. Redox role of ROS and inflammation in pulmonary diseases -- 12. Semaphorin3E/PlexinD1 axis in asthma: what we know so far -- 13. Serine protease inhibitors to treat lung inflammatory diseases -- 14. Sex and Gender Differences in Lung Disease -- 15. Sex hormones and lung inflammation -- 16. Synopsis of Clinical Acute Respiratory Distress Syndrome (ARDS).
    Abstract: Lung diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma. Each year, tens of millions of people develop and can die from lung infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for some patients. Current treatment options for lung disease are neither always effective, nor condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases is not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung disease, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, and students with new perspectives and concepts. The editors hope these books will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
    Type of Medium: Online Resource
    Pages: XVI, 384 p. 42 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030687489
    Series Statement: Advances in Experimental Medicine and Biology, 1304
    URL: https://doi.org/10.1007/978-3-030-68748-9
    DOI: 10.1007/978-3-030-68748-9
    DDC: 571.96
    Language: English
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  • 18
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    Online Resource
    Circulating Tumor Cells : Advances in Liquid Biopsy Technologies (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Cancer Therapy. ; Tumour Biomarkers.
    Description / Table of Contents: Part 1. CTC Technologies -- Affinity -- Physical -- ctDNA -- miRNA -- Exosomes -- Part 2 -- Biology of CTC -- Dormancy -- Culture -- EMT -- ctDNA and Exosomes -- Cells in circulation with CTC -- Part 3 -- CTC Analysis -- IHC, FISH, and other molecular assays -- Functional characterization -- Advanced microscopy and AI -- Analysis of non-cellular circulating markers -- Part 4 -- Clinical Applications of the Liquid Biopsy -- Early detection and cancer screening -- Prognosis and therapeutic monitoring -- Applications in Clinical Trials -- Applications in Drug Development.
    Abstract: It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other emerging aspects of the liquid biopsy, including circulating tumor DNA and methylated DNA (ctDNA, ct meDNA), ctRNA, ct miRNA, circulating tumor proteins (and other) biomarkers and circulating tumor derived exosomes (ctExosomes).
    Type of Medium: Online Resource
    Pages: XXI, 668 p. 77 illus., 72 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031229039
    Series Statement: Current Cancer Research,
    URL: https://doi.org/10.1007/978-3-031-22903-9
    DOI: 10.1007/978-3-031-22903-9
    DDC: 571.978
    Language: English
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  • 19
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    Online Resource
    Neurocognitive Complications of HIV-Infection : Neuropathogenesis to Implications for Clinical Practice (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Neurosciences. ; Virology. ; Immunology. ; Neuroscience. ; Virology.
    Description / Table of Contents: I. Neuropathogenesis and Biomarkers -- New Potential Axes of HIV Neuropathogenesis with Relevance to Biomarkers and Treatment -- Neurocognitive Impairment and Associated Genetic Aspects in HIV Infection -- Inflammatory Mechanisms and Cascades Contributing to Neurocognitive Impairment in HIV/AIDS -- Neuroimaging Advances in Diagnosis and Differentiation of HIV, Comorbidities, and Aging in the cART Era -- II. Neurocognitive Impairments in Low-, Middle- and High-Income Countries – Incidence / Prevalence and Contexts -- Neurocognitive Complications of Pediatric HIV Infections -- Neurocognitive Complications of HIV Infection in Women: Insights from the WIHS Cohort -- Cultural Neuropsychology Considerations in the Diagnosis of HIV- Associated Neurocognitive Disorders -- Neurocognitive Complications of HIV Infection in Low-Income Countries -- Deep Phenotyping of HIV Neurocognitive Complications Among Individuals Residing in High-Income Countries -- Reliably Measuring Cognitive Change in the Era of Chronic HIV Infection and Chronic HIV-Associated Neurocognitive Disorders -- III. Comorbidities and Complications -- Geriatric Syndromes in People Living with HIV Associated with Ageing and Increasing Comorbidities: Implications for Neurocognitive Complications of HIV Infection -- Conceptualizing and Assessing Everyday Functioning in the Context of HIV-Associated Neurocognitive Disorders -- Neuropsychiatric Disorders, Emotional Disturbances, and Their Associations with HIV-Associated Neurocognitive Disorder -- Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders -- HIV-Associated Neurocognitive Disorder (HAND): Relative Risk Factors -- IV. Screening, Interventions and Clinical Management -- Screening for HIV-Associated Neurocognitive Disorders: Sensitivity and Specificity -- Behavioral and Physical Activity Interventions for HAND -- Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging Literature -- Clinical Treatment Options and Randomized Clinical Trials for Neurocognitive Complications of HIV Infection: Combination Antiretroviral Therapy, Central Nervous System Penetration Effectiveness, and Adjuvants.
    Abstract: This volume aims at presenting the latest international research and discoveries in the neurocognitive aspects and complications in HIV/AIDS, and how this understanding can shape and inform how we think about clinical practice and patient care in HIV/AIDS as well as lead to a better understanding of the underlying neuropathogenesis. The chapter, "Metabolic Syndrome and Cardiovascular Disease Impacts on the Pathophysiology and Phenotype of HIV-Associated Neurocognitive Disorders", of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: XVII, 545 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030807597
    Series Statement: Current Topics in Behavioral Neurosciences, 50
    URL: https://doi.org/10.1007/978-3-030-80759-7
    DOI: 10.1007/978-3-030-80759-7
    DDC: 571.96
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  • 20
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    Online Resource
    Antibody Glycosylation (2021)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Pharmacology. ; Biochemical markers. ; Analytical chemistry. ; Biotechnology. ; Immunology. ; Pharmacology. ; Biomarkers. ; Bioanalytical Chemistry. ; Biotechnology.
    Description / Table of Contents: Microheterogeneity of antibody molecules -- Part I: Analytical Methods -- Lectin and LC based methods for immunoglobulin (G) glycosylation analysis -- Mass spectrometry-based methods for immunoglobulin G N-glycosylation analysis -- CE based methods for Ig(G) glycosylation analysis -- Automation of Ig glycosylation analysis -- Bioinformatics in immunoglobulin glycosylation analysis -- Part II: Biosynthesis & Regulation -- N-glycan biosynthesis: Basic principles and factors affecting its outcome -- Genetic regulation of immunoglobulin G glycosylation -- Epigenetics of immunoglobulin G glycosylation -- IgG changes in aging and other inflammatory conditions -- Estrogen-driven changes in immunoglobulin G Fc glycosylation -- Part III: Effector Functions & Diseases -- Sweet rules – linking glycosylation to antibody function -- Immunoglobulin G glycosylation in diseases -- Immunoglobulin A glycosylation and its role in diseases -- Part IV: Applications -- Importance and monitoring of therapeutic immunoglobulin G glycosylation -- Glycosylation of plant-produced immunoglobulins -- The rapidly expanding nexus of immunoglobulin G N-glycomics, suboptimal health status, and precision medicine -- Glycosylation of antigen-specific antibodies - Perspectives on immunoglobulin G glycosylation in vaccination and immunotherapy.
    Abstract: This book summarizes recent advances in antibody glycosylation research. Covering major topics relevant for immunoglobulin glycosylation - analytical methods, biosynthesis and regulation, modulation of effector functions - it provides new perspectives for research and development in the field of therapeutic antibodies, biomarkers, vaccinations, and immunotherapy. Glycans attached to both variable and constant regions of antibodies are known to affect the antibody conformation, stability, and effector functions. Although it focuses on immunoglobulin G (IgG), the most explored antibody in this context, and unravels the natural phenomena resulting from the mixture of IgG glycovariants present in the human body, the book also discusses other classes of human immunoglobulins, as well as immunoglobulins produced in other species and production systems. Further, it reviews the glycoanalytical methods applied to antibodies and addresses a range of less commonly explored topics, such as automatization and bioinformatics aspects of high-throughput antibody glycosylation analysis. Lastly, the book highlights application areas ranging from the ones already benefitting from antibody glycoengineering (such as monoclonal antibody production), to those still in the research stages (such as exploration of antibody glycosylation as a clinical or biological age biomarker), and the potential use of antibody glycosylation in the optimization of vaccine production and immunization protocols. Summarizing the current knowledge on the broad topic of antibody glycosylation and its therapeutic and biomarker potential, this book will appeal to a wide biomedical readership in academia and industry alike. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 591 p. 66 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030769123
    Series Statement: Experientia Supplementum, 112
    URL: https://doi.org/10.1007/978-3-030-76912-3
    DOI: 10.1007/978-3-030-76912-3
    DDC: 571.96
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  • 21
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    Online Resource
    Interaction of Immune and Cancer Cells (2022)
    Cham :Springer International Publishing :
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    Keywords: Tumors Immunological aspects. ; Cancer Treatment. ; Oncology. ; Tumour Immunology. ; Cancer Therapy. ; Oncology.
    Description / Table of Contents: Chapter 1: Cancer immunoediting - elimination, equilibrium and immune escape in solid tumors -- Chapter 2: Tumor – Stroma Interaction and Cancer. - Chapter 3: Tumor-infiltrating lymphocytes and their role in solid tumor progression -- Chapter 4: Tumor-associated macrophages – reasons to be cheerful, reasons to be fearful -- Chapter 5: Polymorphonuclear neutrophils and tumors: friend or foe? -- Chapter 6: Role of NK cells in tumor progression -- Chapter 7: The role of myeloid-derived suppressor cells in tumor growth and metastasis -- Chapter 8: Cancer stem cells – an ever hiding foe -- Chapter 9: Adoptive T-cell immunotherapy – Perfecting self-defenses -- Chapter 10: Monoclonal antibodies to CTLA-4 with focus on ipilimumab.
    Abstract: Now, it its second edition, this book summarizes the role of immune cells in tumor suppression and progression. It describes in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. A newly added chapter also focuses on the role of Natural Killer cells in tumor progression. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for researchers and practitioners working or lecturing in the field of cancer research and immunology.
    Type of Medium: Online Resource
    Pages: XIV, 350 p. 22 illus., 20 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030913113
    Series Statement: Experientia Supplementum, 113
    URL: https://doi.org/10.1007/978-3-030-91311-3
    DOI: 10.1007/978-3-030-91311-3
    DDC: 571.96
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  • 22
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    Online Resource
    Inflammation and Epilepsy: New Vistas (2021)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Neurology . ; Neurosciences. ; Diseases. ; Pharmacology. ; Immunology. ; Neurology. ; Neuroscience. ; Diseases. ; Pharmacology.
    Description / Table of Contents: Pro and Anti-Inflammatory Neurovascular Processes in Epilepsy: A Fragile and Dynamic Equilibrium -- Emerging Molecular Mechanisms of Neuroinflammation in Seizure Disorders -- Glial Mechanisms of Inflammation during Seizures -- Perivascular Inflammation and Extracellular Matrix Alterations in Blood-Brain Barrier Dysfunction and Epilepsy -- Blood T cells and Cytokine Levels during Interictal-Ictal Transitions -- Autoantibodies, Encephalopathies and Epilepsy -- Tau Protein in Drug-Resistant Epilepsy and Cognitive Decline -- Ketogenic Diet, Inflammation and Epilepsy -- Role of Regulatory T cells in Epilepsy -- Inflammation at the Neurovascular Unit in Post-Traumatic Epilepsy.
    Abstract: This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
    Type of Medium: Online Resource
    Pages: VIII, 237 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030674038
    Series Statement: Progress in Inflammation Research, 88
    URL: https://doi.org/10.1007/978-3-030-67403-8
    DOI: 10.1007/978-3-030-67403-8
    DDC: 571.96
    Language: English
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    Cancer Neuroscience (2023)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Cancer Treatment. ; Neurosciences. ; Immunotherapy. ; Cancer Biology. ; Cancer Therapy. ; Neuroscience. ; Cancer Microenvironment. ; Immunotherapy.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Neuronal influence on cancer initiation and growth -- Chapter 2.1 Paracrine signaling in CNS primary tumors and brain metastases -- Chapter 2.2 Paracrine signaling in PNS primary tumors -- Chapter 3. Neuronal influence on cancer invasion and metastasis including perineurial invasion -- Chapter 4. Neurotrophic activity of tumors -- Chapter 5. Cancer interactions with Schwann cells -- Chapter 6. Cancer-glial interactions -- Chapter 7. Neuron-cancer synaptic and other electrical signaling -- Chapter 8. Neuro-immune interactions system and immuno-oncology -- Chapter 9. Nervous system interactions with non-immune elements in the cancer microenvironment -- Chapter 10. Cancer-induced remodeling of the nervous system -- Chapter 11. Cancer and pain -- Chapter 12. Systemic interactions of cancer and the impact on the nervous system -- Chapter 13. Tools and model systems to study nerve-cancer interactions -- Chapter 14. Conclusions and Future Directions.
    Abstract: This volume is the first on the market to address and discuss the emerging field of cancer neuroscience. Edited by pioneers in the field with contributions from top researchers, the volume serves as a comprehensive overview of the role of nerves in tumorigenesis and cancer progression. Chapters will address how the innervation of tumors can serve as both prognostic and predictive biomarkers as well as actionable therapeutic targets. Authors will describe current research efforts, and future directions for study and translation to the clinic. It is becoming increasingly apparent that certain treatments will need to consider interactions between the nervous system and cancer, and the novel concepts presented in the book address related accumulating evidence regarding therapeutic strategies. This unique volume will be useful for cancer researchers, neuroscientists, cancer biologists, oncologists, and others looking to gain a greater understanding of this emerging field.
    Type of Medium: Online Resource
    Pages: XII, 202 p. 21 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031324291
    URL: https://doi.org/10.1007/978-3-031-32429-1
    DOI: 10.1007/978-3-031-32429-1
    DDC: 571.978
    Language: English
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  • 24
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    Online Resource
    Cancer Metastasis Through the Lymphovascular System (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Metastasis. ; Lymphatics. ; Cancer Biology. ; Metastasis. ; Lymphatic System.
    Description / Table of Contents: Section 1: Genetic and Molecular Pathways of Cancer Growth and Metastasis -- Chapter 1. Hallmarks of Cancer: Molecular Underpinnings -- Chapter 2. Unifying concept of genomic changes: The mutational landscape of cancers -- Chapter 3. Tumor Microenvironment: Coconspirator in Tumorigenesis -- Chapter 4. Hallmarks of Metastasis: Molecular Underpinnings -- Chapter 5. Hereditary Cancer Syndromes and Cancer Metastasis -- Section 2: Pathology of Cancer Growth and Metastasis -- Chapter 6. Pathologic Assessment of Lymph Node Metastasis -- Chapter 7. Pathologic Assessment of Systemic or Distant Metastasis -- Chapter 8. The Role of Angiotropic Extravascular Migratory Metastasis in Metastases -- Section 3: Dormant Cancer Cells and their Reactivation in the Host Cancer Microenvironment -- Chapter 9. Tumor Dormancy and Relapse Regulated by the Extracellular Matrix -- Chapter 10. Therapy-Induced Dormancy and Residual Disease -- Section 4: The Microenvironment of Site-Specific Metastasis - Isaac P. Witz -- Chapter 11. The Microenvironment of Site-Specific Metastasis -- Section 5: Circulating Cancer Cells and Liquid Biopsy -- Chapter 12. Circulating tumor cells and ctDNA in sarcomas -- Chapter 13. Liquid biopsy using cell-free tumor DNA for gastrointestinal cancers -- Chapter 14. Circulating tumor cells and ctDNA in prostate cancer.-Chapter 15. Circulating Tumor Cells in Lung Cancer -- Chapter 16. CTCs/ ctDNA and Brain Metastasis.-Chapter 17. Epigenetics and liquid biopsy in oncology: role in metastasis and clinical utility -- Chapter 18. Metabolic reprogramming of circulating tumor cells for metastasis -- Section 6: Lymphatic System and Cancer Metastasis -- Chapter 19. Lymphatic System Biology, Pathobiology, and Relation to Cancer Metastasis -- Chapter 20. Lymphatic Specification and Development, EMT-MET, and Cancer Spread -- Chapter 21. Lymphangiogenesis, Lymph Nodes, Cancer Lymphangiogenesis and Metastasis -- Chapter 22. Immune cell trafficking in the lymphatics, hyaluronan biology and tumour metastasis -- Chapter 23. Lymphvascular Genomics and Proteomics, Clinical Syndromes, and Cancer Metastasis -- Chapter 24. Imaging of the Lymphatic System with Relevance to Cancer and Cancer Metastasis -- Chapter 25. Lymphedema: general pathophysiology, prevention and management in invasive cancer -- Section 7: Radiological Imaging of Early Cancer and Cancer Metastases -- Chapter 26. Primary Tumor Staging and Detection of Common Sites of Distant Metastatic Disease -- Chapter 27. Imaging Modalities in the Detection and Diagnosis of Metastatic Disease -- Chapter 28. Imaging of Bone Metastases -- Chapter 29. Imaging of Lung and Soft Tissue Metastases -- Chapter 30. Image-Guided Biopsy and Intervention for Metastatic Disease -- Section 8: Sentinel Lymph Node Surgery for Solid Cancer. Chapter 31. Sentinel Lymph Node Biopsy for Primary Cutaneous Malignancy -- Chapter 32. Sentinel Lymph Node Biopsy in Breast Cancer -- Chapter 33. Sentinel node navigation surgery for upper gastrointestinal cancer -- Chapter 34. Sentinel Lymph Node Mapping in Non-Small Cell Lung, Colon, and Thyroid Carcinomas -- Section 9: Surgical Treatment of Primary and Metastatic Cancer -- Chapter 35. The efficacy and evolution of surgical management based on cancer biology -- Chapter 36. The role of surgery in managing primary and metastatic melanoma -- Chapter 37. The Role of Surgery in Managing Primary and Metastatic Breast Cancer -- Chapter 38. The role of surgery in managing primary and metastatic colorectal cancer -- Chapter 39. The Role of Surgery in Management of Gastric Cancer -- Chapter 40. The role of surgery in managing primary and metastatic hepatopancreaticobiliary cancers -- Section 10: Cancer Metastasis to the Lung -- Chapter 41. Metastatic disease of the lung -- Section 11: Cancer Metastasis to the Liver -- Chapter 42. Tumor Resection and Ablation as a Means of Controlling Hepatic Metastases -- Chapter 43. Regional Arterial Infusional Therapy as a Means of Controlling Hepatic Metastases -- Section 12: Cancer Metastasis to the Bone -- Chapter 44. Molecular Mechanisms of Metastasis to the Bone.-Chapter 45. Surgical Management of Metastatic Disease to the Upper Extremity -- Chapter 46. Surgical Management of Metastatic Disease to the Lower Extremity -- Chapter 47. Surgical management of metastatic disease to the pelvis -- Chapter 48. Surgical Management of Metastatic Disease to the Spine -- Chapter 49. Interventional radiology techniques for management of skeletal metastases -- Section 13: Cancer Metastasis to the Brain and the Nervous System -- Chapter 50. Brain Metastases: Overview and Molecular Mechanisms -- Chapter 51. Indications and Techniques for Surgical Intervention in Patients with Metastatic Brain Tumors -- Chapter 52. Brain Metastases: Current and Future pharmacological treatment -- Chapter 53. Radiotherapy for CNS Metastases -- Chapter 54. Leptomeningeal Carcinomatoses -- Section 14: Urologic Cancer and 1st Patterns of Metastasis -- Chapter 55. Urologic Cancer and 1st Patterns of Metastasis -- Section 15: Biology and Clinical Aspects of Sarcoma Progression -- Chapter 56. Soft Tissue Sarcoma -- Chapter 57. Bone Sarcoma -- Chapter 58. Liposarcoma Metastasis -- Chapter 59. Desmoid Tumors.-Chapter 60. Atypical patterns of metastases: How do Sarcoma’s metastasize? -- Chapter 61. Tumor Immune Microenvironment of Soft Tissue Sarcoma -- Section 16: The Role of Radiation in the Treatment of Primary and Metastatic Cancer -- Chapter 62. Basic Principles of Radiobiology and Cancer Metastasis Prevention -- Chapter 63. Technical Innovations in the Delivery of Radiation Therapy -- Chapter 64. Radiation Therapy in the Definitive Treatment of Cancer -- Chapter 65. Radiation Therapy for Extracranial Oligometastatic Disease -- Chapter 66. Spine Radiotherapy -- Section 17: Immunotherapy of Solid Malignancies -- Chapter 67. Immunotherapy in Melanoma and Merkel Cell Cancer -- Chapter 68. Landscape of Immunotherapy in Lung Cancer -- Chapter 69. Immuno-oncologic Treatment of Genitourinary Malignancies -- Section 18: Current Topics -- Chapter 70. Personalized Systemic Cancer Therapy -- Chapter 71. Cancer Stem Cells and Their Role in Metastasis -- Chapter 72. HPV Induced Cancers -- Chapter 73. Microbiome and Cancer Metastasis -- Chapter 74. Application of Artificial Intelligence in Research on Cancer and Its Metastasis.
    Abstract: This textbook describes in detail the process of cancer metastasis from a single cell in the primary site through its arduous journey to the sentinel lymph node as the main gateway and beyond to distant sites. The most up-to-date knowledge on key topics in the molecular biology, diagnosis, and treatment of metastatic cancer is highlighted by a large panel of experts. The book begins with a comprehensive overview of the genetic and molecular mechanisms that promote or inhibit cancer metastasis through lymphatic pathways to lymph nodes or through vascular pathways to distant sites, providing the reader with an essential basic knowledge. This is followed by further details on the role of the immune system within the primary tumor and the lymph node and the importance of the microenvironment at the metastatic site. The role of the sentinel lymph node in cancer metastasis is emphasized. Special attention is also given to state-of-the-art imaging techniques for the detection of early-stage cancer and cancer metastases, as well as the use of liquid biopsies in sarcoma, prostate, gastrointestinal, and lung cancer. Clinical patterns of malignant tumors arising in different organ systems are compared, described, and discussed with the goal of determining what similarities and/or differences exist. The book concludes with a detailed discussion of surgical intervention, radiation, and systemic therapy of primary and metastatic cancer, and briefly previews several emerging topics, such as the latest findings on personalized cancer therapy, cancer stem cells, unique molecular mechanisms of virus-induced cancer, the impact of the microbiome on cancer metastasis and the application of artificial intelligence in cancer metastasis research. By providing fundamental knowledge of the biological and clinical aspects of cancer metastasis, this book will be an important reference for cancer researchers, clinical oncologists, teachers, and students. Written by experts in the field, each chapter includes a summary of the chapter's key points and open-ended questions that address pressing issues in the field and encourage the reader to consider future directions. .
    Type of Medium: Online Resource
    Pages: XXIV, 806 p. 145 illus., 106 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030930844
    URL: https://doi.org/10.1007/978-3-030-93084-4
    DOI: 10.1007/978-3-030-93084-4
    DDC: 571.978
    Language: English
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    Amino Acids in Nutrition and Health : Amino Acids in the Nutrition of Companion, Zoo and Farm Animals (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Prelims -- One-carbon metabolism and development of the conceptus during pregnancy: Lessons from studies with sheep and pigs -- Cell-specific expression of enzymes for serine biosynthesis and glutaminolysis in farm animals -- Amino acids in beef cattle nutrition and production (author to be identified) -- Amino acid nutrition and reproductive performance in ruminants -- Amino acids in the nutrition and production of sheep and goats -- Amino acids in swine nutrition and production -- Amino acid nutrition and metabolism in chickens -- Nutrition and functions of amino acids in fish -- Nutrition and functions of amino acids in aquatic crustaceans -- Amino acids in dog nutrition and health -- Amino acids in the nutrition, metabolism, and health of domestic cats -- Amino acid nutrition for optimum growth, development, reproduction, and health of zoo animals.
    Abstract: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in companion (dogs and cats), zoo (carnivores, herbivores, and omnivores), and farm (including cattle, pigs, sheep, goats, chickens, fish, and crustaceans) animals. It enables readers to understand the crucial roles of amino acids and their metabolites in the growth, development, health, and metabolic diseases of these animals. Readers will learn from well-written chapters that amino acids are not only the building blocks of protein but are also signaling molecules and key regulators of gene expression and whole body homeostasis in companion, domestic, aquatic, and captive animals. The book also provides new and useful information on the optimum requirements of the animals for dietary amino acids. This knowledge will guide nutritional practices and daily management to improve the health and survival of all species and to enhance the productivity of livestock, poultry, and aquaculture enterprises worldwide to produce high-quality protein for human consumption. Editor of this volume is an internationally recognized expert in the biochemistry, nutrition and physiology of amino acids. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals and pet owners, as well as undergraduate and graduate students in animal science, aquaculture, zoology, wildlife, veterinary medicine, biology, biochemistry, food science, nutrition, pharmacology, physiology, toxicology, and other related disciplines. In addition, all chapters provide general and specific references to amino acid nutrition and metabolism for researchers and practitioners in animal agriculture, aquaculture, zoos, biomedicine, and plant science, and for government policy makers. Chapter 7 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VI, 256 p. 36 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030544621
    Series Statement: Advances in Experimental Medicine and Biology, 1285
    URL: https://doi.org/10.1007/978-3-030-54462-1
    DOI: 10.1007/978-3-030-54462-1
    DDC: 571.96
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    Amino Acids in Nutrition and Health : Amino Acids in Gene Expression, Metabolic Regulation, and Exercising Performance (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Chapter 1: Regulation of Gene Expression by Amino Acids in Animal Cells -- Chapter 2: Amino acids in cell signaling: regulation and function -- Chapter 3: Amino Acids in Endoplasmic Reticulum Stress and Redox Signaling -- Chapter 4: Amino Acids in Autophagy: Regulation and Function -- Chapter 5: Oxidation of Energy Substrates in Tissues of Fish: Metabolic Significance and Implications for Gene Expression and Carcinogenesis -- Chapter 6: Arginine, Agmatine and Polyamines: Key Regulators of Conceptus Development in Mammals -- Chapter 7: Interorgan Metabolism of Glutamate and Glutamine in Poultry -- Chapter 8: Interorgan Metabolism of Amino Acids in Health and Disease -- Chapter 9: Amino Acids and Their Metabolites for Improving Human Exercising Performance -- Chapter 10: Role of L-Arginine in Nitric Oxide Synthesis and Health in Humans -- Chapter 11: Composition of Amino Acids in Foodstuffs for Humans and Animals -- Chapter 12: Dietary Intakes of Amino Acids and Other Nutrients by Adult Humans.
    Abstract: This book explains about amino acids (AAs) which are not only building blocks of protein, but are also signaling molecules as well as regulators of gene expression and the protein phosphorylation cascade. Additionally, AAs are key precursors for syntheses of hormones and low-molecular-weight nitrogenous substances with each having enormous biological importance. For example, physiological concentrations of AA metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for cell functions. Growing evidence shows that humans and animals have dietary requirements for all proteinogenic AAs. Mammals, birds, and fish also have species- and age-dependent needs for some AA-related substances. However, elevated levels of other products (e.g., ammonia, homocysteine, H2S, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, optimal amounts of AAs and their ratios in diets and circulation are crucial for whole-body homeostasis and health. Adequate provision of one or a mixture of functional AAs or metabolites may be beneficial for ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility). Dietary supplementation of these nutrients can also optimize the efficiency of metabolic transformations to enhance muscle growth, milk production, and athletic performance, while preventing excess fat deposition and reducing adiposity. Therefore, functional AAs hold great promise in improving the growth, health, and well-being of individuals.
    Type of Medium: Online Resource
    Pages: VI, 227 p. 34 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030741808
    Series Statement: Advances in Experimental Medicine and Biology, 1332
    URL: https://doi.org/10.1007/978-3-030-74180-8
    DOI: 10.1007/978-3-030-74180-8
    DDC: 571.96
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    Tumor Microenvironment : State of the Science (2020)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Biomechanics. ; Cancer Biology. ; Biomechanics.
    Description / Table of Contents: Metabolism in the tumor microenvironment -- Neutrophil Elastase and Neutrophil Extracellular Traps in the Tumor Microenvironment -- Viral hepatitis, inflammation, and tumour microenvironment -- Effects of HIV on the tumor microenvironment -- GLI2-mediated inflammation in the tumor microenvironment -- Stellate Cells in the Tumor Microenvironment -- Endothelial Progenitors in the Tumor microenvironment -- Chimeric antigen receptors for the tumour microenvironment -- Toll-Like Receptors (TLRs) in the Tumor Microenvironment (TME): A dragon-Like Weapon in a Non-Fantasy Game of Thrones -- Multiple dynamics in tumor microenvironment under radiotherapy -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research in the field. A variety of topics are covered, including metabolism in the tumor microenvironment, stellate cells and endothelial progenitors in the tumor microenvironment, as well as the effects of HIV, viral hepatitis, and inflammation in the tumor microenvironment, and more. Taken alongside its companion volumes, Tumor Microenvironment: State of the Science updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 208 p. 28 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030445188
    Series Statement: Advances in Experimental Medicine and Biology, 1263
    URL: https://doi.org/10.1007/978-3-030-44518-8
    DOI: 10.1007/978-3-030-44518-8
    DDC: 571.978
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    Tumor Microenvironment : Recent Advances (2020)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Novel techniques to study the bone-tumor microenvironment -- An emerging model for cancer development from a tumor -- microenvironment perspective in mice and humans -- Effects of Exercise on the Tumour Microenvironment -- Effects of inhaled tobacco smoke on the pulmonary tumor microenvironment -- Multimodal molecular imaging of the tumour microenvironment -- Necrosis in the tumor microenvironment and its role in cancer recurrence -- The Multifaceted Effects of Autophagy on the Tumor Microenvironment -- The Sociobiology of Brain Tumors -- Tumor microenvironment conditioning by abortive lytic replication of oncogenic γ-herpesviruses -- The microbiome as a component of the tumor microenvironment -- Index.
    Abstract: This volume discusses recent research advances in cancer biology, focusing on the role of the tumor microenvironment. Taken alongside its companion volumes, Tumor Microenvironment: Recent Advances covers the latest research on various aspects of the tumor microenvironment, as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists studied the tumor microenvironment as well as how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students, as well as researchers seeking an update on research on the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XI, 160 p. 31 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357276
    Series Statement: Advances in Experimental Medicine and Biology, 1225
    URL: https://doi.org/10.1007/978-3-030-35727-6
    DOI: 10.1007/978-3-030-35727-6
    DDC: 571.978
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    Tumor Microenvironment : Non-Hematopoietic Cells (2020)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Adipocytes in the tumour microenvironment -- Fibroblasts in the tumor microenvironment -- Mesenchymal stem cells in the tumor microenvironment -- Hepatic stellate cells in liver tumor -- Pancreatic stellate cells: The key orchestrator of the pancreatic tumor microenvironment -- Endothelial cells in the tumor microenvironment -- Lymphatic endothelial cell progenitors in the tumor microenvironment -- Oligodendrocyte progenitors in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on non-hematopoietic cells within the tumor microenvironment.Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include fibroblasts, adipocytes, mesenchymal stem cells, stellate cells, and more. Taken alongside its companion volumes, Tumor Microenvironment: Non-Hematopoietic Cells updates us on what we know about the different aspects of the tumor microenvironment as well as future directions. Useful for introducing the newer generation of researchers to the history of how scientists focused in the tumor microenvironment and how this knowledge is currently applied for cancer treatments, it will be essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment. All of the chapter authors are renowned international experts in the cancer biology field in specific subfields that will be the focus of their chapters.
    Type of Medium: Online Resource
    Pages: X, 129 p. 31 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030371845
    Series Statement: Advances in Experimental Medicine and Biology, 1234
    URL: https://doi.org/10.1007/978-3-030-37184-5
    DOI: 10.1007/978-3-030-37184-5
    DDC: 571.978
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    Diseases of the Breast during Pregnancy and Lactation (2020)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Human physiology. ; Medicine Research. ; Biology Research. ; Gynecology . ; Cancer Biology. ; Human Physiology. ; Biomedical Research. ; Gynecology.
    Description / Table of Contents: Preface -- PART 1: Basic Considerations -- Anatomy and Physiology of the Breast during Pregnancy and Lactation -- Diagnosis of Breast Disorders in Pregnancy and Lactation -- Clinical Presentations of Breast Disorders in Pregnancy and Lactation -- PART 2: Benign and Premalignant Disorders of the Breast in Pregnancy and Lactation -- Benign Disorders of the Breast in Pregnancy and Lactation -- Mastitis, Breast Abscess, and Granulomatous -- Premalignant disorders of the Breast in Pregnancy and Lactation -- PART 3: Breast Cancer in Pregnancy and Lactation -- Epidemiology of Pregnancy-Associated Breast Cancer -- Histology of Pregnancy-Associated Breast Cancer -- Clinical presentation, Diagnosis, and Prognosis of Pregnancy-Associated Breast Cancer -- . Treatment of Pregnancy-Associated Breast Cancer -- Special Clinical Situations -- Prenatal Care during and after Breast Cancer Treatment -- Lactation during and after Breast Cancer -- Pregnancy in Breast Cancer Survivors. Impact of Breast Cancer Treatment on Fertility -- Fertility Counseling and Preservation for Breast Cancer Patients -- Pregnancy after Breast Reconstruction -- Pregnancy and Lactation: Risk or Protective Factors for Breast Cancer -- Psychological Aspects of Pregnancy and Lactation in Patients with Breast Cancer.
    Abstract: Symptoms of the breast in gravid women commonly represent physiological changes, however they may also be related to serious underlying breast disease; this challenging dilemma is aggravated by diagnostic and therapeutic limitations imposed by safety issues regarding the mother and fetus. A comprehensive coverage of all aspects of normal and pathologic breast changes during pregnancy and lactation, their diagnosis and management is provided in the present work. The organized structure of this book begins with gestational changes of the breast, while discussing safety, hazards, and arguments regarding diagnostic approaches. It then goes on by describing various clinical presentations and common and uncommon benign disorders during gravidity. The book then addresses pre-malignant lesions of the breast, opening the dialogue on how to manage these confusing lesions in pregnant and nursing women. It continues toward pregnancy-associated breast cancer, focusing on every facet of the problem, including epidemiology, diagnosis, treatment and complications, anesthetic considerations, prenatal care, and rare malignancies; and comes to an end by arguing main psychological concerns. In the midst of this orderly sequence fertility issues, pregnancy, and breastfeeding in women who have overcome their breast cancer are also discussed. This unique reference has been written by academic experts from different centers and diverse disciplines in a practical format. It is intended to be an ideal resource for every practitioner and specialist who manages complaints of gravid and nursing women or treats breast disorders in women of child bearing age.
    Type of Medium: Online Resource
    Pages: XXV, 216 p. 55 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030415969
    Series Statement: Advances in Experimental Medicine and Biology, 1252
    URL: https://doi.org/10.1007/978-3-030-41596-9
    DOI: 10.1007/978-3-030-41596-9
    DDC: 571.978
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    Systems Biology of MicroRNAs in Cancer (2022)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Tumor markers. ; Non-coding RNA. ; Cancers. ; Tumour Biomarkers. ; Non-coding RNAs.
    Description / Table of Contents: Chapter 1. The Role of MicroRNAs in Cancer Biology and Therapy from a Systems Biology Perspective -- Chapter 2. Circulating MicroRNAs as Cancer Biomarkers in Liquid Biopsies -- Chapter 3. Regulation of Immune Cells by MicroRNAs and MicroRNA-Based Cancer Immunotherapy -- Chapter 4. Machine-Learning-Based Methods and Best Practices of MicroRNA-Target Prediction and Validation -- Chapter 5. Turning Data to Knowledge: Online Tools, Databases and Resources in MicroRNA Research -- Chapter 6. Bioinformatics Methods for Modeling MicroRNA Regulatory Networks in Cancer -- Chapter 7. Analysis of the p53/MicroRNA Network in Cancer -- Chapter 8. Machine Learning Using Gene-Sets to Infer miRNA Function -- Chapter 9. miRNA:miRNA Interactions: A Novel Mode of miRNA Regulation and Its Effect on Disease -- Chapter 10. ClustMMRA v2: A Scalable Computational Pipeline for the Identification of MicroRNA Clusters Acting Cooperatively on Tumor Molecular Subgroups -- Chapter 11. 3D Modeling of Non-coding RNA Interactions.
    Abstract: This book provides an update on the latest development in the field of microRNAs in cancer research with an emphasis on translational research. Since the early 2000s, microRNAs have been recognized as important and ubiquitous regulators of gene expression. Soon it became evident that their deregulation can cause human diseases including cancer. This book focuses on the emerging opportunities for the application of microRNA research in clinical practice. In this context, computer models are presented that can help to identify novel biomarkers, e.g. in circulating microRNAs, and tools that can help to design microRNA-based therapeutic interventions. Other chapters evaluate the role of microRNAs in immunotherapy, immune responses and drug resistance. Covering key topics on microRNAs in cancer research this book is a valuable resource for both emerging and established microRNA researchers who want to explore the potential of microRNAs as therapeutic targets or co-adjuvants in cancer therapies.
    Type of Medium: Online Resource
    Pages: VII, 317 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031083563
    Series Statement: Advances in Experimental Medicine and Biology, 1385
    URL: https://doi.org/10.1007/978-3-031-08356-3
    DOI: 10.1007/978-3-031-08356-3
    DDC: 571.978
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    Tumor Microenvironment : Extracellular Matrix Components – Part B (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Stem cells. ; Regenerative medicine. ; Cytology. ; Cancer Microenvironment. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Cell Biology.
    Description / Table of Contents: Elastin in the Tumor Microenvironment -- Decorin in the tumor microenvironment -- Syndecan-1 in the tumor microenvironment -- Versican in the tumor microenvironment -- Chondroitin Sulphate Proteoglycans in the Tumour Microenvironment -- Lipoproteins and the Tumor Microenvironment -- The Role of BEHAB/Brevican in the Tumor Microenvironment: Mediating Glioma Cell Invasion and Motility -- Thrombospondin in Tumor Microenvironment -- Tenascin-C function in glioma: immunomodulation and beyond -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components of the tumor microenvironment during cancer development. Furthermore, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include elastin, decorin, syndecan-1, versican, lipoproteins, brevican, thrombospondin, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part B updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newest generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book is an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapters authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.
    Type of Medium: Online Resource
    Pages: XIII, 178 p. 36 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030484576
    Series Statement: Advances in Experimental Medicine and Biology, 1272
    URL: https://doi.org/10.1007/978-3-030-48457-6
    DOI: 10.1007/978-3-030-48457-6
    DDC: 571.978
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    Immunotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Immunology. ; Oncology. ; Cancer Biology. ; Immunology. ; Oncology.
    Description / Table of Contents: Overview of Basic Immunology and Clinical Application -- Advances in Diagnostic Procedures and their Applications in the era of Cancer Immunotherapy -- Immunotherapy for Melanoma -- Immunotherapy in Lung Cancer: From a minor God to the Olympus -- Immunotherapy in Gastrointestinal Malignancies -- Current Landscape of Immunotherapy in Genitourinary Malignancies -- Immuno-oncology for Gynecologic Malignancies -- Immunotherapy for Neuro-Oncology -- Immunotherapy and Radiation -- CAR T-cells -- Skin Reactions to Immune Checkpoint Inhibitors -- Gastrointestinal Tract Adverse Events -- Immune-Related Adverse Events: Pneumonitis -- Hepatobiliary Adverse Events -- Immune Checkpoint Inhibitors (ICIs) Related Cardiotoxicity -- Renal Toxicity -- Immune-Related Oral, Otologic and Ocular Adverse Events -- Cancer Imaging in Immunotherapy -- The Microbiome in Immuno-Oncology -- New developments in the use of Patient-reported outcomes in Cancer Patients undergoing Immunotherapies.
    Abstract: Immunotherapy is a rapidly evolving field that mandates frequent revision of the book as new insights to fight cancer emerge. The third edition of Immunotherapy is an updated overview of immuno-oncology in different cancer types and toxicities associated with immunotherapy. It explores the breath of immunotherapeutic strategies available to treat a wide range of cancers, from melanoma and non-small cell lung cancer to gastrointestinal, genitourinary, gynecologic and nervous system malignancies. With increasing use of checkpoint inhibitors as standard of care and in clinical trials, the challenges associated with their use undoubtedly increase. As objective response is limited to a subset of patients and is often associated with distinct immune related side effects that are potentially life threatening, it is essential to identify patients who are likely to respond to immunotherapy and those who are at a risk for developing treatment-related side effects. In the absence of a validated predictive biomarker, innovative technologies and assays are being used to identify critical biomarkers that drive the immune response. Hence, a chapter to provide a basic understanding of the diagnostic procedures has been included besides the chapter on the cellular components of the human immune system. This new edition will also inform readers on use of novel microbiome and imaging approaches. Finally, the book includes a chapter on patient-reported outcomes in patients treated with immunotherapies as the authors recognize the importance of including missing patient voice in clinical trials and longitudinal assessment of symptom reports. In short, the third edition of this book provides a comprehensive overview of the latest developments in the field of immune-oncology that will help health care professionals make informed treatment decisions. The book’s chapters are written by a diverse cast of experts conducting cutting-edge research, providing the reader with the most up-to-date science.
    Type of Medium: Online Resource
    Pages: XII, 339 p. 44 illus., 35 illus. in color. , online resource.
    Edition: 3rd ed. 2020.
    ISBN: 9783030410087
    Series Statement: Advances in Experimental Medicine and Biology, 1244
    URL: https://doi.org/10.1007/978-3-030-41008-7
    DOI: 10.1007/978-3-030-41008-7
    DDC: 571.978
    Language: English
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    Circulating Tumor Cells in Breast Cancer Metastatic Disease (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Stem cells. ; Cancer Biology. ; Biomedical Research. ; Biotechnology. ; Stem Cell Biology.
    Description / Table of Contents: Preface -- Introduction – Biology of Breast Cancer Metastasis and Importance of the Analysis of CTCs -- Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis -- Disseminated Tumor Cells and Dormancy in Breast Cancer Progression -- Methodology for the Isolation and Analysis of CTCs -- Advances in the Characterization of Circulating Tumor Cells in Metastatic Breast Cancer: Single Cell Analyses and Interactions, and Patient-derived Models for Drug Testing -- Circulating Tumor Cells (CTCs) Heterogeneity in Metastatic Breast Cancer: Different Approaches for Different Needs -- Relevance of CTC Clusters in Breast Cancer Metastasis -- Epigenetics of Circulating Tumor Cells in Breast Cancer -- Circulating Tumor Cells: Applications for Early Breast Cancer -- Clinical Relevance and Therapeutic Application of CTCs in Advanced Breast Cancer. .
    Abstract: This book compiles the latest research and key findings about the role of circulating tumor cells (CTCs) in Breast Cancer progression, both from the research and clinical standpoint. Based on latest advancements, the content of the book is set out to provide a clear overview about the biology and use of CTCs as a tool for the monitoring and management of breast cancer patients. This work covers basic concepts about the process of metastasis, the biology of CTCs and their potential applications as a biomarker in breast cancer. It will enable readers to delve into the process of epithelial-mesenchymal plasticity (EMP), mechanisms and clinical implications of tumor cell dormancy and minimal residual disease, and into the phenotypical and molecular heterogeneity of CTCs and CTC clusters, including the epigenetic characterization of CTCs. Readers will find out about the key technologies used for the isolation of CTCs as well as the latest advances towards the characterization of CTCs, involving single cell analyses and patient-derived models. It will discuss the evidences about the use of CTCs as a tool to monitor breast cancer progression and therapy response, as well as to unravel mechanisms of resistance to therapy and to identify new therapeutic targets favoring the development of novel anticancer drugs. Lastly, it will discuss ongoing clinical trials and try to foresee the future of CTCs in terms of clinical application and implementation in the clinical routine. The topic of this book is particularly relevant for cancer researchers and oncologist with an interest in the field, looking to refresh or to broaden their knowledge and understanding about the use of CTCs as a diagnostic biomarker in breast cancer.
    Type of Medium: Online Resource
    Pages: XV, 167 p. 15 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030358051
    Series Statement: Advances in Experimental Medicine and Biology, 1220
    URL: https://doi.org/10.1007/978-3-030-35805-1
    DOI: 10.1007/978-3-030-35805-1
    DDC: 571.978
    Language: English
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    Western Blotting for the Non-Expert (2021)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Biotechnology. ; Immunology. ; Biomedical Research. ; Biotechnology.
    Description / Table of Contents: Western blotting: How it began -- 2. Basics of Western Blotting -- 3.Basic Calculations in Western Blotting -- 4.Choosing The Right Antibody For Western Blotting -- 5. Sample Preparation -- 6. Blocking membranes at places that do not have transferred proteins -- 7. A Basic Method for Western Blotting -- 8. Trouble Shooting Western Blotting -- 9. Using Biotin to demonstrate western and dot blotting in University Practical Classes- A Guide To Instructors -- 10. Nitrocellulose Membrane Art -- 11. The Use Of A Harmless Invisible Ink To Send Secret Messages On Nitrocellulose Membranes And As A Substitute For The Harmful Radioactive Ink Used As A Marker In ECL Membrane Assays -- 12. Fingerprinting On Nitrocellulose And Polyvinylidene Difluoride Membrane -- 13. Spectrometric Determination Of Protein For Electrophoresis -- 14. Concentrating Proteins For Western Blotting -- 15. Dissolving Proteins Using Lysis Buffer -- 16. Blotting And Detecting Glycosaminoglycans -- 17. Passive Blotting From Tissue Slices -- 18. Localizing Proteins by Tissue Printing -- 19. Ultrasound Blotting -- 20. Obtaining Several Blots From A Single SDS-PAGE Gel By Passive Transfer -- 21. Diffusion Blotting From SDS-PAGE Gels Supported By Solid Plastic -- 22. Dot-Immunobinding -- 23. Simultaneous Immunoblotting Analysis With Activity Gel Electrophoresis -- 24. Protein Blotting By Centrifugation -- 25. Blotting And Immunostaining Of Multiple Antigenic Peptides -- 26. High Molecular Weight Protein Blotting Using Agarose Gel Electrophoresis -- 27. Cetyltrimethylammonium bromide PAGE And Eastern Blotting -- 28. Purification Of Autoantibodies Bound To An Autoantigen Immobilized On A Membrane Strip -- 29. Miniaturized Blotting -- 30. Affinity Immunoblotting -- 31. Transferring Coomassie Blue Stained Proteins from Polyacrylamide Gels To Transparencies -- 32. Protein Transfer From Immobilized pH Gradient Gels -- 33. SDS PAGE To Immunoblotting In Sixty Minutes -- 34. Western Blot Analysis Of Protein-DNA Complexes Formed DuringGel Shift Experiments -- 35. Electrophoretic Transfer Of High And Low Molecular Weight Proteins To Membranes Using Heat -- 36. Grid-immunoblotting -- 37. Far-western Blotting -- 38. Native Electrophoresis And Western Blot Analysis -- 39. Efficient Electroblotting Of Low Molecular Weight Protein After Staining With Coomassie -- 40. Avoiding Non-specific Binding Of Secondary Antibodies In Immunoblotting By Double-blotting -- 41.A Brief Introduction To Other Protein Blotting Methods -- 42. Quantitative Computerized Western Blotting In Detail -- 43. Common Problems In Electrophoresis.
    Abstract: This book fills the need for a simplified text covering western blotting protocols aimed not just at high school and college students, but the researcher with little to no experience in these techniques. It provides the principles, basic methodology, and tips and tricks to avoiding the common pitfalls of western blotting. The book also introduces simple protocols that can transform western blotting into a fun method, such as sending secret messages on membranes or using nitrocellulose membrane as a canvas for art. In addition to the techniques, this book also covers the history of western blotting, which originated from the development of the blotting of DNA. It then delves into the importance of protein blotting, brought to the fore by the fact that the procedure has been evolving constantly since its inception in 1979, and the fact that the scientific community is faced with a multitude of ways and means of transferring proteins to membranes.
    Type of Medium: Online Resource
    Pages: XXIII, 467 p. 611 illus., 170 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030706845
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-70684-5
    DOI: 10.1007/978-3-030-70684-5
    DDC: 571.96
    Language: English
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    Anoikis : How the Extracellular Matrix Regulates Life-or-Death Decisions (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Cell death. ; Cancer Biology. ; Cell Death.
    Description / Table of Contents: Preface -- Introduction -- The intersection of anoikis resistance and fatty acid metabolism in cancer -- Anoikis resistance in melanoma -- Anoikis mediated by stress-activated MAPK signaling pathways -- Metabolic Regulation of Anoikis -- Metabolic Reprogramming contributes to Anoikis resistance in Cancer Cells -- Role of the nuclear receptors in anoikis -- The roles of anoikis in cervical cancer -- Shc and the control of small GTPase dynamics in cellular anchorage -- Anoikis and the Human Gut Epithelium in Health and Disease -- Epithelial cell extrusion: the prelude to anoikis -- Microtubule modifications and mitochondria: role in anoikis.
    Abstract: This book provides a useful resource for graduate-level cancer cell biology courses. Since the first report, in 1994, of “anoikis”—the apoptosis that occurs when cells lack appropriate contact with the extracellular matrix—over 2,100 papers have been published on this subject. This book is the first comprehensive, in-depth and up-to-date compendium on anoikis. Chapters are authored by some of the leading researchers in the field. This book provides both mechanistic and translational information regarding anoikis, in a convenient format. Mechanistically, the following topics will be addressed in detail: The role of MAP kinase signaling The role of Shc proteins as cellular anchorage sensors The role of cellular metabolism, and fatty acid metabolism in particular, and how they are affected by oncogenic transformation How epithelial cell extrusion – the prelude to anoikis—is regulated in normal and cancer cells The convergence of TGF-b and androgen receptor signaling in the regulation of anoikis This book also discusses the specialized functions and dysregulation of anoikis in the following cancer settings: Colon cancer Melanoma Cervical cancer The book serves to update i nvestigators actively working on problems in the anoikis field, in either experimental or translational settings. For investigators encountering novel biological phenomena that might relate to anoikis, it serve as an entry point to the literature that does not require an extensive background in cell adhesion signaling or apoptosis mechanisms. .
    Type of Medium: Online Resource
    Pages: VIII, 202 p. 6 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030738563
    URL: https://doi.org/10.1007/978-3-030-73856-3
    DOI: 10.1007/978-3-030-73856-3
    DDC: 571.978
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    Molecular Biology of Human Cancers (2023)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Medicine Research. ; Biology Research. ; Oncology. ; Cancer Biology. ; Biomedical Research. ; Oncology.
    Description / Table of Contents: Part I: Molecules, Genes, Cells and Mechanisms -- Chapter 1: An Introduction to Human Cancers -- Chapter 2: Cancer Genetics -- Chapter 3: DNA Damage and DNA Repair -- Chapter 4: Oncogenes -- Chapter 5: Tumor Suppressor Genes -- Chapter 6: Cancer Pathways -- Chapter 7: Cell Death and Replicative Senescence in Cancer -- Chapter 8: Cancer Epigenetics -- Chapter 9: Invasion and Metastasis -- Part II: Human Cancers -- Chapter 10: Leukemias And Lymphomas -- Chapter 11: Pediatric Cancers -- Chapter 12: Cancers of the Skin -- Chapter 13: Colorectal Cancer -- Chapter 14: Bladder Cancer -- Chapter 15: Lung Cancer -- Chapter 16: Renal Cell Carcinomas -- Chapter 17: Liver Cancer -- Chapter 18: Gastric Cancer -- Chapter 19: Breast Cancer -- Chapter 20: Prostate Cancer -- Part Iii: Prevention, Diagnostics and Therapy -- Chapter 21: Cancer Prevention -- Chapter 22: Cancer Diagnostics -- Chapter 23: Cancer Therapy.
    Abstract: This textbook describes the most relevant molecular and biological processes in cancer, how they contribute to the development and progression of individual cancer types in humans, and how insights from molecular cancer research can be applied to improve cancer prevention, diagnostics and treatment. Part I of the textbook summarizes the current fundamental knowledge on the general properties of cancers, the causes of cancer, cancer genetics, genomics and epigenetics. Individual chapters address the functions of DNA damage and repair, oncogenes and tumor suppressors in carcinogenesis and discuss crucial mechanisms in cancer pathogenesis, such as apoptosis and replicative senescence, as well as the most relevant signal transduction pathways and regulatory networks. Part I concludes with a chapter on tumor invasion and metastasis and tumor immunology. In Part II, the most relevant mechanisms acting in individual human cancers (and subtypes) are described in more detail. This central part of the book contains individual sections on the most common human cancers highlighting the diversity in their genetic, molecular and cellular pathogenic mechanisms. How insights from molecular cancer research are translated into improvements in prevention, diagnosis, and treatment is outlined in Part III. This new edition has been extensively revised and includes in particular updated information on cancer genomics, epigenetics, viral carcinogenesis, cancer diagnostics and cancer therapy and a new chapter on lung cancers. Now more than ever, cancer research is an interdisciplinary endeavor that requires a basic knowledge of commonly used terms, facts and concepts. The aim of this book is to provide advanced students and practitioners in various disciplines with this foundation, bridging the gap between standard textbooks of molecular biology, pathology and oncology on the one hand and the specialized cancer literature on the other.
    Type of Medium: Online Resource
    Pages: XXI, 542 p. 229 illus., 221 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031162862
    URL: https://doi.org/10.1007/978-3-031-16286-2
    DOI: 10.1007/978-3-031-16286-2
    DDC: 571.978
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    Medical and Biomedical Updates (2021)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Human physiology. ; Respiratory organs. ; Physiology. ; Immunology. ; Human Physiology. ; Respiratory Physiology.
    Description / Table of Contents: Role of IP3 Receptors in Shaping the Carotid Chemoreceptor Response to Hypoxia but not to Hypercapnia in the Rat Carotid Body: An Evidence Review -- The Role of Hyperbaric Oxygen Treatment for COVID-19: A Review -- Primary Immunodeficiencies - Diseases of Children and Adults: A Review -- Pneumococcal Vaccine in Adult Asthma Patients -- Immunoglobulin G Deficiency in Children with Recurrent Respiratory Infections with and without History of Allergy -- Pruritus Characteristics in Severe Atopic Dermatitis in Adult Patients -- Pathophysiological Responses to a Record-Breaking Multi-Hour Underwater Endurance Performance: A Case Study -- Respiratory Muscle Strength and Ventilatory Function Outcome: Differences between Trained Athletes and Healthy Untrained Persons -- Uroflowmetry and Altitude Hypoxia: A Report from Healthy Italian Trekkers and Nepali Porters during Himalayan Expedition -- Effects of Intraligamentary Injection of Osteogenic-Induced Gingival Fibroblasts on Cementum Thickness in the Dog Model of Tooth Root Resorption -- In-Silico Evaluation of Treatment of Periprosthetic Fractures in Elderly Patients after Hip Arthroplasty -- Appraisal of burden of caregivers to chronically rehabilitated patients with spinal cord injuries in a tertiary neurological center in Nepal.
    Abstract: This book integrates topics in basic research and clinical medicine as well as molecular and cell biology. It presents innovative advances in the field of immunodeficiency syndromes and viral/bacterial respiratory infections, including a novel hyperbaric oxygen treatment for COVID-19. A comprehensive insight is offered into the unresolved molecular pathways in chemosensing that plays a vital role in detecting insufficient tissue oxygenation, as well as in sporting accomplishments. Other articles address cardiorespiratory and humoral responses to hypoxia, the function of cementum in the repair and regeneration of teeth, and periprosthetic fractures following hip arthroplasty in the elderly. The issue of the overwhelming burdens on caregivers to spinal injury patients, damaging both health and psychosocial status, is addressed. The book promotes translation of scientific advances to the general medical practice. It will be a valuable reference for clinical healthcare professionals and researchers interested in innovative practices to improve the prevention, diagnosis, and management of diseases.
    Type of Medium: Online Resource
    Pages: VI, 131 p. 20 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030672164
    Series Statement: Clinical and Experimental Biomedicine, 1289
    URL: https://doi.org/10.1007/978-3-030-67216-4
    DOI: 10.1007/978-3-030-67216-4
    DDC: 571.96
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    Inflammation, Infection, and Microbiome in Cancers : Evidence, Mechanisms, and Implications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Cancer. ; Medical microbiology. ; Medicine Research. ; Biology Research. ; Human physiology. ; Immunology. ; Cancer Biology. ; Medical Microbiology. ; Biomedical Research. ; Human Physiology. ; Immunology.
    Description / Table of Contents: Chapter 1: The Microbiome And The Hallmarks Of Cancer -- Chapter 2: Microbiome In Human GI Cancers -- Chapter 3: The Gut Microbiome And Colorectal Cancer -- Chapter 4: Salmonella Infection In Human Cancers -- Chapter 5: Biomarkers Of Esophageal Cancers And Precancerous Lesions -- Chapter 6: Epithelial And Immune Cell Responses To Helicobacter Pylori That Shape The Gastric Tumor Microenvironment -- Chapter 7: Microbiome And Liver Cancer -- Chapter 8: THE MICROBIOME AND UROLOGIC CANCERS -- Chapter 9: Role Of Infections And Tissue Inflammation In The Pathology Of The Fallopian Tube And High-Grade Serous Ovarian Cancer -- Chapter 10: Commensal Microbes And Their Metabolites: Influence On Host Pathways In Health And Disease -- Chapter 11: Dietary And Microbiome In Cancer Prevention -- Chapter 12: Autophagy And Cancer-Current Biology And Drug Development -- Chapter 13: Mitochondrial Regulation Of Inflammation In Cancer -- Chapter 14: Modern Germ-Free Study Designs And Emerging Static Housing Technology In A Growing ‘Human Microbiome’ Market -- Chapter 15: Machine Learning In Identification Of Disease-Associated Microbiota -- Chapter 16: Mediation Analysis Of Microbiome Data And Detection Of Causality In Microbiome Studies.
    Abstract: This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
    Type of Medium: Online Resource
    Pages: XII, 509 p. 31 illus., 28 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030679514
    Series Statement: Physiology in Health and Disease,
    URL: https://doi.org/10.1007/978-3-030-67951-4
    DOI: 10.1007/978-3-030-67951-4
    DDC: 571.978
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    The Extracellular Matrix and the Tumor Microenvironment (2022)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Cytology. ; Clinical biochemistry. ; Cancer Biology. ; Cell Biology. ; Medical Biochemistry.
    Description / Table of Contents: Chapter 1: Small leucine-rich proteoglycans regulate cancer cell growth, apoptosis-and associated inflammation -- Chapter 2: The role of decorin in cancer -- Chapter 3: The mystery of syndecan-1 in tumor development and progression -- Chapter 4:Syndecan-2 Biology and its Role in Colorectal Carcinoma -- Chapter 5: Versican in Tumor Progression, Tumor-Host Interactions and Cancer Immunotherapy -- Chapter 6:Circulating proteoglycans/glycosaminoglycans as cancer biomarkers -- Chapter 7: Hyaluronan in the Extracellular Matrix of hematological and solid tumors. Its biological effects" -- Chapter 8: Heparanase: a paramount enzyme for cancer initiation, progression and metastasis -- Chapter 9: Laminins and matrix metalloproteinases connection: a subtle relationship that can go wrong in a tumor context, particularly if CD44 gets involved -- Chapter 10:Basement membrane, collagen, and fibronectin: physical interactions with cancer cells -- Chapter 11: Integrins in cancer: re-focusing on the tumor microenvironment -- Chapter 12: Adipose compounds in breast tumor extracellular matrix -- Chapter 13: Extracellular matrix as a metabolic niche in cancer -- Chapter 14: The role of inflammatory cells in tumor angiogenesis -- Chapter 15: Cancer angiogenesis and its master regulator perlecan -- Chapter 16: The microRNA-extracellular matrix interplay in breast cancer -- Chapter 17: The impact of the extracellular matrix on immunotherapy success -- Chapter 18: Exploiting hyaluronan-CD44 network in tumor therapy.
    Abstract: This book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression. Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression. Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. This book is an interesting read for anyone who want to know more about ECM and cancer biology. Early career scientists can use it as an introduction to the field, offering an excellent tool for studying ECM. Advanced researchers and clinicians can gain a broader overview of the subject, considering the role of ECM for influencing every cancer hallmark as well as in the response of cancer treatments. The work serves to inspire future research and shows that the ECM should be considered as an important factor in the development of cancer therapeutics. The series "Biology of Extracellular Matrix" is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
    Type of Medium: Online Resource
    Pages: X, 494 p. 40 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030997083
    Series Statement: Biology of Extracellular Matrix, 11
    URL: https://doi.org/10.1007/978-3-030-99708-3
    DOI: 10.1007/978-3-030-99708-3
    DDC: 571.978
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    Mathematical, Computational and Experimental T Cell Immunology (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Bioinformatics. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Cytokine receptor signaling and CD4/CD8 lineage choice during T cell development in the thymus -- An agent-based model of T helper cell fate decisions in the thymus -- Modelling naive T cell homeostasis -- Mechanistic models of CD4 T cell homeostasis and reconstitution in health and disease -- Section 1MODELING THE DYNAMICS OF CD4+ T CELLS IN HIV- 1 INFECTION -- Modelling the response to Interleukin-7 therapy in HIV-infected patients -- Modeling immunopathology during persistent viral infections -- Delay in differentiation may suggest division of labour in models for CD8+ T cell differentiation -- Inferring differentiation order in adaptive immune responses from population level data -- Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes -- The public face and private lives of T cell receptor repertoires -- Population dynamics of immune repertoires -- Mathematical Modelling of T cell activation -- Agent-based model of heterogeneous T cell activation in vitro -- CTLA-4 mediated ligand trans-endocytosis: a stochastic model -- Automated gating and dimension reduction of high-dimensional cytometry data -- Index.
    Abstract: The purpose of this book is to present current mathematical and computational models that are used to describe and characterise the immunology of T cells. The reader will be exposed to a variety of tools/methods that go hand-in-hand with the T cell-mediated immunological process that is being modelled. We aim in the proposed book to emphasise the role that mathematical (or computational) modelling has already played in Immunology. Each chapter will provide an example of the contribution of mathematics to T cell immunology under one of the following four headings: i) Generation of hypotheses, ii) Quantification of immunological processes, iii) Definition of observables to measure given an experimental objective, iv) reconciling disparate (or even conflicting) experimental results. .
    Type of Medium: Online Resource
    Pages: X, 298 p. 74 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030572044
    URL: https://doi.org/10.1007/978-3-030-57204-4
    DOI: 10.1007/978-3-030-57204-4
    DDC: 571.96
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    Hormonal Pathology of the Uterus (2020)
    Cham :Springer International Publishing :
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    Keywords: Cancer. ; Endocrinology. ; Pathology. ; Cancer Biology. ; Endocrinology. ; Pathology.
    Description / Table of Contents: 1. Biophysiology of the uterus: development, cyclic changes, menopause -- 2. Hormonal effects in reproductive technology (ovulation stimulation, in vitro fertilization) -- 3. Hormonal role and therapy in common benign uterine lesions: endometrial polyps, leiomyomas, adenomyosis -- 4. Endometrial hyperplasia; precancerous lesions of the endometrium. Hormone therapy -- 5. Endometrial Carcinoma. Endometriosis, Hormonal Role in Carcinogenesis. Hormonal Therapy -- 6. Menopausal Hormone Therapy. Contraceptives -- 7. Replacement hormone therapy for gender dysphoria and congenital sexual anomalies -- 8. Hormone therapy for endometrial neoplasia related to breast cancer therapy (Tamoxifen) -- 9. Endometrial histopatholigic changes in hormonal therapy (contraceptives, ovulation stimulation, hormone replacement therapy, hormonal antitumoral therapy).
    Abstract: Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women. Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly related to hormonal and metabolic factors. In addition, breast cancer treated with hormone therapy (Tamoxifen) may, in some cases, be associated with uterine pathology. Hormone therapy is used to improve the physiological effects and counteract abnormal and deleterious effects of “natural” hormonal activity. Millions of women receive hormone therapy at some point of their life: using oral contraceptives, reproductive technology, treatment for post-menopausal symptoms, among other uses. This book addresses a range of women’s health issues, from fertility to neoplasms, and their relationship with natural and iatrogenic hormonal effects. Chapters include clinical and pathological descriptions, theoretical and practical medical issues, and original studies and cases. Controversial issues in certain hormone therapies are presented with updated concepts based on clinical studies and novel statistical methods. The book will be useful for specialized and general physicians, oncologists, endocrinologists, researchers, medical students, and others in the field of women’s health. .
    Type of Medium: Online Resource
    Pages: VIII, 185 p. 66 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030384746
    Series Statement: Advances in Experimental Medicine and Biology, 1242
    URL: https://doi.org/10.1007/978-3-030-38474-6
    DOI: 10.1007/978-3-030-38474-6
    DDC: 571.978
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    Lung Inflammation in Health and Disease, Volume I (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Human physiology. ; Medicine Research. ; Biology Research. ; Respiratory organs Diseases. ; Immunology. ; Human Physiology. ; Biomedical Research. ; Pneumology.
    Description / Table of Contents: 1. Potential role of mast cells in regulating corticosteroid insensitivity in severe asthma -- 2. Galectin-3 Promotes ROS, Inflammation and Vascular Fibrosis in Pulmonary Arterial Hypertension -- 3. Anti-Inflammatory Effects of Statins in Lung Vascular Pathology: From Basic Science to Clinical Trials -- 4. Evolving Schema for Employing Network Biology Approaches to Understand Pulmonary Hypertension -- 5. Pulmonary Inflammation and KRAS Mutation in Lung Cancer -- 6. microRNA Targets for Asthma Therapy -- 7. Roles of genetic predisposition in the sex-bias of pulmonary pathophysiology, as a function of estrogens -- 8. Hypercapnic respiratory failure-driven skeletal muscle dysfunction: It is time for animal mod-els-based mechanistic research -- 9. Role of airway smooth muscle in inflammation related to asthma and COPD -- 10. Systemic Sclerosis and Pulmonary Disease -- 11. Innate Lymphoid Cells in airway inflammation -- 12. Sjogren’s Syndrome and pulmonary disease -- 13. Redox Regulation, Oxidative Stress and Inflammation in Group 3 Pulmonary Hypertension -- 14. Sex-Steroid Signaling in Lung Diseases and Inflammation -- 15. Cytokines, Chemokines and Inflammation in Pulmonary Arterial Hypertension -- 16. Interactive roles of CaMKII/Ryanodine Receptor Signaling and Inflammation in Lung Diseases -- 17. Reciprocal Correlations of Inflammatory and Calcium Signaling in Asthma Pathogenesis -- 18. Crosstalk between Lung and Extrapulmonary Organs in Infection and Inflammation -- 19. Inflammation in Pulmonary Arterial Hypertension -- 20. Lysophospholids in Lung Inflammatory Diseases.
    Abstract: Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from respiratory infections such as pneumonia and TB. Systemic inflammation may induce and exacerbate local inflammatory diseases in the lungs, and local inflammation can in turn cause systemic inflammation. There is increasing evidence of the coexistence of systemic and local inflammation in patients suffering from asthma, COPD, and other lung diseases, and the co-morbidity of two or more local inflammatory diseases often occurs. For example, rheumatoid arthritis frequently occurs together with, and promotes the development of, pulmonary hypertension. This co-morbidity significantly impacts quality of life, and can result in death for those affected. Current treatment options for lung diseases are neither always effective, nor often condition-specific; there is a desperate need for novel therapeutics in the field. Additionally, the molecular and physiological significance of most major lung diseases are not well understood, which further impedes development of new treatments, especially in the case of coexistent lung diseases with other inflammatory diseases. Great progress has been made in recent years in many areas of the field, particularly in understanding the molecular geneses, regulatory mechanisms, signalling pathways, and cellular processes within lung diseases, as well as basic and clinical technology, drug discovery, diagnoses, treatment options, and predictive prognoses. This is the first text to aggregate these developments. In two comprehensive volumes, experts from all over the world present state-of-the-art advances in the study of lung inflammation in health and disease. Contributing authors cover well-known as well as emerging topics in basic, translational, and clinical research, with the aim of providing researchers, clinicians, professionals, fellows, and students with new perspectives and concepts. The editor hopes this book will also help to direct future research in lung disease and other inflammatory diseases, and result in the development of novel therapeutics.
    Type of Medium: Online Resource
    Pages: XV, 409 p. 54 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030630461
    Series Statement: Advances in Experimental Medicine and Biology, 1303
    URL: https://doi.org/10.1007/978-3-030-63046-1
    DOI: 10.1007/978-3-030-63046-1
    DDC: 571.96
    Language: English
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    Essential Aspects of Immunometabolism in Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Human physiology. ; Pathology. ; Immunology. ; Human Physiology. ; Pathology.
    Description / Table of Contents: Overview of Immune response -- Metabolic Pathway: from biochemistry to bench -- Mitochondrial biogenesis and dynamics in healthy and diseases -- Epigenetic regulation of metabolic pathways -- Metabolic pathways and cells signaling -- Metabolic profile of innate and adaptive immune cells -- Metabolic sensors and immunopathology -- Obesity, metabolic syndrome and inflammation.
    Abstract: Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.
    Type of Medium: Online Resource
    Pages: XII, 278 p. 38 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030866846
    URL: https://doi.org/10.1007/978-3-030-86684-6
    DOI: 10.1007/978-3-030-86684-6
    DDC: 571.96
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    Pathogenesis of Systemic Lupus Erythematosus : Insights from Translational Research (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Medicine Research. ; Biology Research. ; Cytokines. ; Immunology. ; Biomedical Research. ; Cytokines and Growth Factors.
    Description / Table of Contents: Advances in translational science to identify new therapies for systemic lupus erythematosus -- Hallmark of systemic lupus erythematosus: Role of B Cell Hyperactivity. Fabien B Vincent, William A Figgett and Margaret L Hibbs -- B cell targeted therapies in systemic lupus erythematosus -- Type I Interferons and the perpetuation of a loss of tolerance -- Therapeutic Modulation of the Interferon Pathway in Systemic Lupus Erythematosus -- The concept of co-stimulatory blockade in SLE -- Cytokines: their role in amplifying SLE pathogenesis -- Intracellular targets in SLE -- Regulatory T cells in SLE -- Balancing strategies: GC and GILZ Axis.
    Abstract: The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to immune tolerance and are amongst the latest focus of therapeutic development in SLE.
    Type of Medium: Online Resource
    Pages: XXI, 178 p. 36 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030851613
    URL: https://doi.org/10.1007/978-3-030-85161-3
    DOI: 10.1007/978-3-030-85161-3
    DDC: 571.96
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    Emerging Modalities in Mitigation of Antimicrobial Resistance (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Immune response. ; Pathogenic microorganisms. ; Natural immunity. ; Biotechnology. ; Immunology. ; Antimicrobial Responses. ; Innate Immunity. ; Biotechnology.
    Description / Table of Contents: 1. Antimicrobials in livestock production and its cross-domain dynamics -- 2. Antibiotics and resistance in environment -- 3. Antimicrobials in agriculture and its implications in antimicrobial resistance -- 4. Modern diagnostic tools for rapid detection of multidrug resistance -- 5. The use of antimicrobials in agriculture and socio-economic considerations in a global world -- 6. Epidemiology of microbial infections -- 7. Socioeconomic impact of antimicrobial resistance and their integrated mitigation by One Health approach -- 8. Regulations in antimicrobial drug development: Challenges, and new incentives -- 9. New insights into and updates on antimicrobial agents -- 10. Polyphenols as emerging antimicrobial agents -- 11. Antimicrobial peptides and small molecules as antibiotics substitute -- 12. Molecular mechanisms of antimicrobial resistance in S. aureus biofilms -- 13. Antimicrobial resistance: Meaning and developing realization -- 14. Chemical diversity in fungi: strategies to mitigate antimicrobial resistance -- 15. Phage therapy as an alternative treatment in the fight against AMR: Real-world problems and possible futures -- 16. Omics and in-silico approaches in the surveillance and monitoring of antimicrobial resistance -- 17. Antimicrobial activity of bioactive compounds (Thymoquinone & Eugenol) and its nanoformulations therapeutic potential -- 18. Nanoparticles as a future alternative against multiple drug resistance -- 19. Nano-cargos boarded defensins to combat multi-drug resistance -- 20. Implementation of nano-vehicles to disguise and fight multi-drug resistance -- 21. Silver nanoparticles as potent multi-drug resistant in-corporants in biomedicine -- 22. Role of gold nanoparticles against bacterial multidrug resistance (MDR): An emerging therapeutic revolution -- 23. Carbon nanoparticles: A potential cost-effective approach to counter antimicrobial resistance -- 24. Antimicrobial interfaces as augmentative strategy against antimicrobial resistance -- 25. Nano-Strategies against rising antimicrobial resistance (AMR): Metallic nanoparticles as nano-weapon. .
    Abstract: This book provides an overview of cutting-edge and next-generation research and technologies for combating antimicrobial resistance. Antibiotic-resistant infections are projected to cause 10 million deaths annually by the year 2050. A sustainable, unified approach by researchers, practitioners, policymakers, and the public is urgently needed to stem this trend. This book aims to provide a comprehensive summary of current and future-facing efforts to mitigate the threat of AMR through a One-Health approach. This book is a valuable resource for students, researchers, policymakers, and the public about AMR and novel strategies to combat AMR.
    Type of Medium: Online Resource
    Pages: XII, 577 p. 62 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841263
    URL: https://doi.org/10.1007/978-3-030-84126-3
    DOI: 10.1007/978-3-030-84126-3
    DDC: 571.96
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    Chikungunya Virus (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Immunology. ; Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology.
    Description / Table of Contents: Preface -- Molecular Virology of Chikungunya Virus -- Understanding molecular pathogenesis with chikungunya virus research tools -- Chronic Chikungunya Virus Disease -- Chikungunya Virus Vaccines: Platforms, Progress, and Challenges -- Small Molecule Inhibitors Targeting Chikungunya Virus.
    Abstract: This book provides readers with a collection of latest reviews written by Chikungunya virus (CHIKV) research leaders who cover topics related to CHIKV replication, advances in CHIKV research reagents and model system development, as well as the pathogenesis of chronic CHIKV disease. Moreover, the volume updates on recent progress in the development of therapeutics and vaccines for treatment and prevention of CHIKV-induced disease. Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has re-emerged to become a significant global disease threat. Although CHIKV has historically been associated with localized outbreaks of debilitating polyarthralgia in Africa and Asia, factors such as increased global travel and viral adaptation to new mosquito vectors have led to the introduction and spread of CHIKV in new regions of the world, including the Americas. The re-emergence of CHIKV has stimulated significant interest both in understanding the biology of CHIKV and in the development of medical countermeasures against the virus.
    Type of Medium: Online Resource
    Pages: XI, 139 p. 10 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030906108
    Series Statement: Current Topics in Microbiology and Immunology, 435
    URL: https://doi.org/10.1007/978-3-030-90610-8
    DOI: 10.1007/978-3-030-90610-8
    DDC: 571.96
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    Evolution, Biodiversity and a Reassessment of the Hygiene Hypothesis (2022)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Inflammation. ; Autoimmunity. ; Allergy. ; Immunology. ; Inflammation. ; Autoimmunity. ; Allergology.
    Description / Table of Contents: Chapter 1. From observing children in traditional upbringing to concepts of health -- Chapter 2. Human evolution, microorganisms, socioeconomic status and reconciling necessary microbial exposures with essential hygiene -- Chapter 3. Biodiversity, microbiomes, and human health -- Chapter 4. Regulation of host immunity by the gut microbiota -- Chapter 5. The gut microbiota and host metabolism -- Chapter 6. The impacts of the microbiota on animal development and physiology -- Chapter 7. The development of the gut microbiota in childhood, and its distortion by lifestyle changes -- Chapter 8. Distortion of the microbiota of the natural environment by human activities -- Chapter 9. The nature and functions of vertebrate skin microbiota -- Chapter 10. The influence of the microbiota on brain structure and function: Implications for stress-related neuropsychiatric disorders -- Chapter 11. Neurodegenerative diseases and the gut microbiota -- Chapter 12. Clinical application of the biodiversity hypothesis in the management of allergic disorders. .
    Abstract: This edited collection of 12 chapters by research workers from a wide range of disciplines resolves the confusion that currently surrounds the “hygiene hypothesis” by considering the human need for exposure to microorganisms from an evolutionary point of view. The book explains why we evolved a requirement for exposure to microbiota from our mothers, from other people, and from the natural environment. It also explains the physiological roles of these exposures, what goes wrong when the exposures are distorted and how human lifestyles and activities, including degradation of the natural environment, are leading to this distortion. Particular attention is given to the range of pathologies associated with inappropriate microbial exposures and inappropriate colonization, including immunoregulatory problems such as allergies and autoimmunity, metabolic problems such as obesity and diabetes, and problems of central nervous system function and neurodegeneration. This book is of profound relevance to most medical disciplines, but also to those concerned with preserving the natural environment and with developing healthier urbanisation.
    Type of Medium: Online Resource
    Pages: X, 414 p. 46 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030910518
    Series Statement: Progress in Inflammation Research, 89
    URL: https://doi.org/10.1007/978-3-030-91051-8
    DOI: 10.1007/978-3-030-91051-8
    DDC: 571.96
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    mRNA Vaccines (2022)
    Cham :Springer International Publishing :
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    Keywords: Immunology. ; Pharmacology. ; Internal medicine. ; Clinical biochemistry. ; Immunology. ; Pharmacology. ; Internal Medicine. ; Medical Biochemistry.
    Description / Table of Contents: Preface -- mRNA-based vaccines and mode of action -- Self-Amplifying mRNA-Based Vaccine Technology and its Mode of Action -- Formulation and Delivery Technologies for mRNA Vaccines -- Messenger RNA-based vaccines against infectious diseases -- Emerge gate for Therapeutics applications of mRNA based drug -- Clinical Development of mRNA Vaccines: Challenges and Opportunities -- Regulatory Considerations on the Development of mRNA Vaccines.
    Abstract: The formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume. The applications of the mRNA technology is covered, focusing on infectious diseases but also touching on other indications, such as immunotherapies and molecular therapies. Potent and long-lasting immune responses observed in animal models, encouraging data from early human clinical studies, together with the success of two mRNA-based COVID-19 vaccines support the use of mRNA-based vaccination as an attractive alternative to conventional vaccine approaches. Consequently, the development progress of the technology, particularly on production, capabilities, and clinical development is reviewed. Topics on safety, regulatory issues, and possible challenges to the mRNA vaccination approach round off this book. Thanks to their high potency, the prospect for generic, low-cost manufacturing processes, and entirely synthetic nature, the future for mRNA vaccines is highly promising. Importantly, mRNA vaccines have the potential to minimize the time between pathogen identification and vaccine release with a huge impact on public health. As the mRNA-based vaccination technology has been progressing rapidly, the book is intended to be an end-to-end review series, covering everything from basic RNA biology and preclinical studies to the manufacturing strategy, clinical development and regulatory approval. It provides established RNA researchers and developers with updates on the latest advancements in the field and allows for a quick but comprehensive overview of this transformative technology, its application, and future potential.
    Type of Medium: Online Resource
    Pages: XI, 205 p. 8 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031180705
    Series Statement: Current Topics in Microbiology and Immunology, 437
    URL: https://doi.org/10.1007/978-3-031-18070-5
    DOI: 10.1007/978-3-031-18070-5
    DDC: 571.96
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    Glaciers and Ice Sheets in the Climate System : The Karthaus Summer School Lecture Notes (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Climatology. ; Environment. ; Physical geography. ; Geology. ; Climate Sciences. ; Environmental Sciences. ; Physical Geography.
    Description / Table of Contents: Flow of ice -- Thermal structure -- Basal processes -- Tidewater glaciers -- Ice shelves D ocean interaction -- Polar meteorology -- Mass balance -- Numerical methods -- Inverse modeling -- Analytic ice sheet models and climate change -- Firn -- Ice cores -- Remote sensing -- Geophysics -- Geodynamics -- Paleo-ice sheets -- Geomorphology -- Glacier fluctuations -- Tropical glaciers -- Historical glaciology.
    Abstract: Our realisation of how profoundly glaciers and ice sheets respond to climate change and impact sea level and the environment has propelled their study to the forefront of Earth system science. Aspects of this multidisciplinary endeavour now constitute major areas of research. This book is named after the international summer school held annually in the beautiful alpine village of Karthaus, Northern Italy, and consists of twenty chapters based on lectures from the school. They cover theory, methods, and observations, and introduce readers to essential glaciological topics such as ice-flow dynamics, polar meteorology, mass balance, ice-core analysis, paleoclimatology, remote sensing and geophysical methods, glacial isostatic adjustment, modern and past glacial fluctuations, and ice sheet reconstruction. The chapters were written by thirty-four contributing authors who are leading international authorities in their fields. The book can be used as a graduate-level textbook for a university course, and as a valuable reference guide for practising glaciologists and climate scientists.
    Type of Medium: Online Resource
    Pages: XXVII, 530 p. 283 illus., 214 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030425845
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-030-42584-5
    DOI: 10.1007/978-3-030-42584-5
    DDC: 551
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    Sustainable Groundwater Management : A Comparative Analysis of French and Australian Policies and Implications to Other Countries (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Environmental management. ; Power resources. ; Environment. ; Water. ; Hydrology. ; Geology. ; Environmental Management. ; Natural Resource and Energy Economics. ; Environmental Sciences. ; Water.
    Description / Table of Contents: Chapter 1. Sustainable Groundwater Management in France and Australia: Setting Extraction Limits, Allocating Rights and Reallocation -- Chapter 2. Groundwater in France: Resources, Use and Management Issues -- Chapter 3. Groundwater Policy in France: From Private to Collective Management -- Chapter 4. Groundwater Management Planning at the River Basin District Level: Comparative Analysis of the Adour-Garonne and Loire-Bretagne River Basins -- Chapter 5. Lessons from Twenty Years of Local Volumetric Groundwater Management: The case of the Beauce Aquifer, Central France -- Chapter 6. Groundwater in Australia: Occurrence and Management Issues -- Chapter 7. The Evolution of Groundwater Management Policy in the States of Australia -- Chapter 8. Developing a Coordinated Groundwater Management Plan for the Interstate Murray-Darling Basin -- Chapter 9. Information Systems for Sustainable Management of Groundwater Extraction in France and Australia -- Chapter 10. The Challenge of Making Ground-water Visible: A Review of Communication Approaches and Tools in France -- Chapter 11. Conceptual Approaches, Methods and Models used to Assess Abstraction Limits for Unconfined Aquifers in France -- Chapter 12. Setting Sustainable Abstraction Limits in Confined Aquifers: Example from Deep Confined Aquifers in the Bordeaux Region, France -- Chapter 13. A tool to Determine Annual Ground-Water Allocations in the Tarn-et-Garonne Alluvial Aquifer (France) -- Chapter 14. Conceptual Approaches, Methods and Models used to Assess Extraction Limits in Australia: From Sustainable to Acceptable Yield -- Chapter 15. Case Study: An Integrated Approach to Determining Sustainable Abstraction Limits in Perth’s North West Urban Growth Corridor -- Chapter 16. Using Resource Condition Limits to Define Groundwater Management Objectives in the Barossa Valley, South Australia -- Chapter 17. Reducing Entitlements when Groundwater has been Over-allocated: Policy Issues and Options -- Chapter 18. Developing Substitution Resources as Compensation for Reduced Groundwater Entitlements: The Case of the Poitou Marshes (France) -- Chapter 19. New Approaches for Allocation Reductions and Groundwater Salinity Management in South Australia -- Chpater 20. Reducing Groundwater Entitlements in the Lower Murrumbidgee Groundwater Management Area -- Chapter 21. Development of Groundwater Markets in Australia: Insights from Victoria in the Murray Darling Basin -- Chapter 22. Groundwater Regulation, Compliance and Enforcement: Insights on Regulators, Regulated Actors and Frameworks in New South Wales, Australia -- Chapter 23. Compliance and Enforcement: the Achilles Heel of French Water Policy -- Chapter 24. The Role of Sectoral Policies to Restore Groundwater Balance: The Impact of Agricultural Policies on Irrigation Water Demand in France -- Chapter 25. Groundwater Management Lessons from Chile -- Chapter 26. California’s 2014 Sustainable Groundwater Management Act – From the Back Seat to the Driver Seat in the (Inter)National Groundwater Sustainability Movement -- Chapter 27. Changing from Unrestricted access to Sustainable Abstraction Management Regimes: Lessons Learnt from France and Australia. .
    Abstract: This book describes and analyses the diversity of possible approaches and policy pathways to implement sustainable groundwater development, based on a comparative analysis of numerous quantitative management case studies from France and Australia. This unique book brings together water professionals and academics involved for several decades in groundwater policy making, planning or operational management to reflect on their experience with developing and implementing groundwater management policy. The data and analysis presented accordingly makes a significant contribution to the empirical water management literature by providing novel, real world insights unpublished elsewhere. The originality of the contributions also lies in the different disciplinary perspectives (hydrogeology, economics, planning and social sciences in particular) adopted in many chapters. The book offers a unique comparative analysis of France, Australia and experiences in countries such as Chile and the US to identify similarities, but also fundamental differences, which are analysed and presented as alternative policy options – these differences being mainly related to the role of the state, the community and market mechanisms in groundwater management.
    Type of Medium: Online Resource
    Pages: XVII, 562 p. 149 illus., 143 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030327668
    Series Statement: Global Issues in Water Policy, 24
    URL: https://doi.org/10.1007/978-3-030-32766-8
    DOI: 10.1007/978-3-030-32766-8
    DDC: 551
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    Geology of the Cayman Islands : Evolution of Complex Carbonate Successions on Isolated Oceanic Islands (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Water. ; Hydrology. ; Sedimentology. ; Earth sciences. ; Geography. ; Geology. ; Water. ; Sedimentology. ; Earth Sciences. ; Geography.
    Description / Table of Contents: Introduction -- Tectonic Setting of Cayman Islands -- Stratigraphic framework -- The Bluff Group -- The Ironshore Formation -- Modern marine sediments of the Cayman Islands -- Dolomitization of the Bluff Group -- Karst and caves -- Phosphates, terra rossa and mangrove peat -- Modern Hydrology -- Summary Information Database.
    Abstract: Grand Cayman, Little Cayman, and Cayman Brac are, in reality, the summits of independent fault blocks that rise from the depths of the Caribbean Sea. This book traces the geological evolution of these islands over the last 30 to 35 million years. The balance between deposition of carbonate sediments and karst development of the exposed land was dictated by the interaction between ever-changing sea levels and vertical tectonic movement of the fault blocks. Today, drinking water needed for the ever-increasing populations of the islands is supplied largely by desalinization plants that are located in accord with a detailed knowledge of the bedrock. This book is based on an extensive data base that has been assembled over the last 40 years of field work and laboratory analyses. Noteworthy aspects of this database include: Approximately 60 visits to the islands over last 40 years – sampling and documentation of virtually every accessible outcrop on the islands (including some that no longer exist). Most samples have been fully documented petrographically and geochemically. Data from 120 wells that have been drilled to depths up to 245 m (most less than 125 m). Wells have been cored and/or chip sampled. Full documentation of drilling histories, XRD analyses of samples, extensive geochemical analyses for major and minor elements, stable isotopes, 87Sr/86Sr ratios, and Rare Earth Elements from numerous samples. Mapping and sampling of modern sediments, including sediment cores, from most of the lagoons around Grand Cayman. Extensive thin section petrography, scanning electron microscope, and electron microprobe analyses of the dolostones and limestones that form the bedrock of the islands. Samples and data collected from numerous caves on Grand Cayman and Cayman Brac have been used to track their developmental history. Detailed analyses of phosphates collected from Little Cayman. Detailed analyses of terra rossa collected from each of the islands.
    Type of Medium: Online Resource
    Pages: XIII, 291 p. 247 illus., 232 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031082306
    URL: https://doi.org/10.1007/978-3-031-08230-6
    DOI: 10.1007/978-3-031-08230-6
    DDC: 551
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    Seasonal Flood Forecasts and Warning Response Opportunities : ENSO Applications in Bangladesh (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Environment. ; Physical geography. ; Environmental management. ; Natural Hazards. ; Environmental Sciences. ; Earth System Sciences. ; Environmental Management.
    Description / Table of Contents: TABLE OF CONTENTS Preface: Why ENSO-based seasonal forecasts are important in Bangladesh Acknowledgements -- About the author -- Chapter 1: Introduction—Seasonal Flood Potential in Bangladesh -- Chapter 2: Basin-wide Hydro-Meteorological Variability and Opportunity for Seasonal -- Forecasts in Bangladesh -- Chapter 3: History of Flood Forecasts and Early Warning in Bangladesh -- Chapter 4: Overview of Weather, ENSO, and Climate Scale -- Chapter 5: The El Niño-Southern Oscillation (ENSO) and Seasonal Flooding in Bangladesh -- Chapter 6: Seasonal Flood Potential in Bangladesh -- Chapter 7: Overview of Eastern, Mixed, and Central Pacific El Niño -- Chapter 8: Seasonal Sea Level Information and Flood Forecast Potential in Bangladesh -- Chapter 9: Consensus Seasonal Flood Forecasts and Warning Response in Bangladesh -- Chapter 10: ENSO Impacts, Applications, and Conclusions.
    Abstract: This book explores the feasibility of using El Niño-Southern Oscillation (ENSO)-based forecasts and early warning systems to prevent losses from floods and droughts in Bangladesh. Despite advances in short-range flood forecasting and information dissemination systems in Bangladesh, the present system is less than satisfactory. This is due to short lead-time products, outdated dissemination networks, and lack of direct feedback from the end-user. One viable solution is to produce long-lead seasonal forecasts—the demand for which is significantly increasing in Bangladesh— and disseminate these products through appropriate channels. As observed in other regions, the success of seasonal forecasts, in contrast to short-term forecasts, depends on consensus among the participating institutions. Therefore, the primary objective of the book is to revisit and modify the framework of an ideal warning response system for issuance of consensus seasonal flood forecasts in Bangladesh. The book discusses issues related to the 5-stage Flood Forecasts, Warning, and Response System (FFWRS) and emphasizes the role of the seasonal ‘Climate Outlook Forum (COF)’ in Bangladesh. The book also identifies ways to improve forecasting and early warning systems by utilizing ENSO-based climate data and models, and discusses a comprehensive and participatory approach to seasonal flood hazard management in Bangladesh. Several successful case examples of ENSO-based seasonal forecasts and early warning systems from other ENSO-sensitive regions have been documented. The primary audience includes academics and students, government policymakers, engineers, and business leaders.
    Type of Medium: Online Resource
    Pages: XXX, 201 p. 84 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031178252
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    URL: https://doi.org/10.1007/978-3-031-17825-2
    DOI: 10.1007/978-3-031-17825-2
    DDC: 551
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    Suriname Revisited: Economic Potential of its Mineral Resources (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Mineralogy. ; Power resources. ; Geology. ; Mineralogy. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Geology of Suriname -- Chapter 3. A Brief History of Exploration Work -- Chapter 4. Modeling Potential: Minimal Economic Resource Parameters -- Chapter 5. Gold -- Chapter 6. Bauxite -- Chapter 7. Base metals -- Chapter 8. Other Metallic Minerals -- Chapter 9. Critical Raw Materials -- Chapter 10. Other Minerals -- Chapter 11. Looking ahead.
    Abstract: This book summarizes the exploration history and provides a framework for assessing the economic potential of the country’s minerals by defining minimal deposit parameters for the various commodities present. Suriname was explored extensively for mineral occurrences in the course of the previous century, indicating the presence of a range of commodities. The country mined and processed bauxite for a century (until 2016), and has an even longer history of small-scale alluvial gold mining; it is currently home to two major gold producers. However, exploration activities have been limited during the past 4 decades as most parts of Suriname’s interior are difficult to access, making geological fieldwork both difficult and expensive. Further, the markets and prices have changed in the interim, which calls for a fresh look at the historic data. .
    Type of Medium: Online Resource
    Pages: XV, 90 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030402686
    Series Statement: SpringerBriefs in Earth Sciences,
    URL: https://doi.org/10.1007/978-3-030-40268-6
    DOI: 10.1007/978-3-030-40268-6
    DDC: 551
    Language: English
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    Online Resource
    Slate as Dimension Stone : Origin, Standards, Properties, Mining and Deposits (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Mineralogy. ; Conservation biology. ; Ecology . ; Geotechnical engineering. ; Geology. ; Mineralogy. ; Conservation Biology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: 1.Slate in architecture -- 2.The origin of slate -- 3.Methodology and standards -- 4.Properties of slate -- 5.Weathering of slate -- 6.Mining of slate and production -- 7.Slate deposits.
    Abstract: This book offers a comprehensive review devoted exclusively to slate as dimension stone. Beginning with a description of the slate as dimension stone, the book describes the origin of slate and related geological phenomena. It thoroughly explains key data acquisition methods and techniques, which are accompanied by extensive data. In turn, slate standards are introduced and compared with regard to their importance for product quality. The book covers in detail the specific petrographical, fabric, strength, physical properties and weathering behaviour of slates. The chapter on mining and production provides an overview of the different forms of exploitation and related geotechnical aspects, together with production and workflow design, from the beginning to the final product. The second part comprises a thorough description of worldwide slate deposits and their geology, properties and appearance as well as a brief introduction of the history. Given its scope and accessible format, the book represents an essential guide for scientists, engineers, and professionals in geology, conservation science, architecture, and mining, as well as readers who are active in the slate industry.
    Type of Medium: Online Resource
    Pages: XI, 492 p. 305 illus., 283 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030356675
    Series Statement: Springer Mineralogy,
    URL: https://doi.org/10.1007/978-3-030-35667-5
    DOI: 10.1007/978-3-030-35667-5
    DDC: 551
    Language: English
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  • 56
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    Online Resource
    The Geology of Kuwait (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Sedimentology. ; Paleontology . ; Geophysics. ; Geology. ; Sedimentology. ; Paleontology. ; Geophysics.
    Description / Table of Contents: Chapter 1. Surface Geology of Kuwait -- Chapter 2. Subsurface stratigraphy of Kuwait -- Chapter 3. Sand dunes in Kuwait, morphometric and chemical characteristics -- Chapter 4. Marine Geology of Kuwait -- Chapter 5. Structures and Tectonics of Kuwait.
    Abstract: This open access book contains a set of chapters covering all aspects of geosciences related to Kuwait and adjactent regions, including Iran, Saudi Arabia and the Arab Gulf states. It covers basic information about the geology including a wide range of geoscientific disciplines such as marine geology, structural geology, hydrogeology and geophysics related to the region. This book is aimed at researchers and students, as well as professionals in the field of hazard mitigation and petroleum exploration.
    Type of Medium: Online Resource
    Pages: XII, 242 p. 211 illus., 177 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031167270
    Series Statement: Regional Geology Reviews,
    URL: https://doi.org/10.1007/978-3-031-16727-0
    DOI: 10.1007/978-3-031-16727-0
    DDC: 551
    Language: English
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  • 57
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    Introduction to GNSS Geodesy : Foundations of Precise Positioning Using Global Navigation Satellite Systems (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Measurement. ; Measuring instruments. ; Geographic information systems. ; Geotechnical engineering. ; Geology. ; Measurement Science and Instrumentation. ; Geographical Information System. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Chapter 1-Introduction -- Chapter 2-Reference systems in GNSS geodesy -- Chapter 3-Estimating geodetic parameters from GNSS -- Chapter 4-GNSS satellite tracking and observation models -- Chapter 5-Geodetic CORS and tracking networks -- Chapter 6-Satellite orbit determination -- Chapter 7-GNSS data processing and biases -- Chapter 8-GNSS software and online tools -- Chapter 9-GNSS geodetic solution exchange formats -- Chapter 10-GNSS time series combinations and data products -- Chapter 11-Geospatial applications of GNSS geodesy -- Chapter 12-Scientific applications of GNSS geodesy.
    Abstract: Introduction to GNSS Geodesy is a concise reference for beginners and experts in GNSS-based satellite geodesy. It covers all of the important concepts in almost a third of the space of the other GNSS books. Th e book begins with a case study in Augmented Reality to set the stage for what is to come and then moves on to the key elements of GNSS geodesy that make accurate and precise geopositioning possible. For example, it is important to understand the geodetic reference systems and the associated GNSS data processing strategies that enable both accurate and high-precision geopositioning. Chapter 2 gives an overview of GNSS constellations and signals, highlighting important characteristics. Chapter 3 then introduces reference systems in geodesy, covering such topics as time systems, geodetic datums, coordinate systems, coordinate conversions and transformations, and International Terrestrial Reference Frame. Th is lays the framework for the rest of the book. Chapters 4 and 5 dig deep into mathematical formulation of GNSS parameter estimation and observation models. All the concepts are presented clearly and concisely, with diagrams to assist reader comprehension. Chapter 6 describes Continuously Operating Reference Station (CORS) networks and their role in geodesy and definition of reference frames. Various global and regional CORS networks are presented in this section. Th e chapter also covers GNSS data and common formats such as RINEX and RTCM. Chapter 7 introduces the whole cycle of GNSS data processing, including preprocessing, ambiguity fixing, and solution reprocessing methods as commonly used in both epoch solutions and time series data. Th e book concludes with appendices on orbit modelling, GNSS linear combinations, application examples, and an example linear model.
    Type of Medium: Online Resource
    Pages: XV, 166 p. 43 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030918217
    URL: https://doi.org/10.1007/978-3-030-91821-7
    DOI: 10.1007/978-3-030-91821-7
    DDC: 551
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  • 58
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    Structural Geology and Tectonics Field Guidebook—Volume 2 (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Sedimentology. ; Paleontology . ; Petrology. ; Geology. ; Sedimentology. ; Paleontology. ; Petrology.
    Description / Table of Contents: Chapter 1 - Field guide for a complete cross-section of the Central Andes along main roads (Carla Cristine Porcher, Márcia Elisa Boscato Gomes, Amós Martini, Giuseppe Betino De Toni, João Pacífico Machado) -- Chapter 2 – Structures associated with the dynamics of granitic rock emplacement (NW Portugal) (Jorge Pamplona, Benedito C. Rodrigues, Mark Peternell, Alex Lorenz, Alex Schimdt, Melissa Mengert, Thomas Altmeyer, Jonas Köpping) -- Chapter 3 - Tectonically significant fault zones in Central Europe (Germany, Czech Republic and Poland) and their surface and subsurface outcrops: Franconian Line, Hronov-Porici Fault, Sudetic Marginal Fault and Lusatian Fault (Lucie Novakova) -- Chapter 4 - Geological field observations along the Pandoh Syncline:the Mandi-Kataula-Bajura section of Himachal Pradesh, NW-India (Paramjeet Singh, Pratap Chandra Sethy, Hrithik Rastogi, M. Rajanikanta Singh, A. Krishnakanta Singh, Satyajit Singh Thakur, Saurabh Singhal) -- Chapter 5 - The rock outcrops at Raghunathdi, SE of Ghatsila (Jharkhand, India): A spectacular preservation of polyphase folding (Srinanda Ganguly, Arpita Samanta, Abhik Kundu) -- Chapter 6 - Spectacular soft-sediment deformation structures in sedimentary rock outcrops of Damodar Valley Basin, West Bengal, India: A field guide (Arpita Samanta, Abhik Kundu) -- Chapter 7 - Structural geological field guide: Bhuj area (Gujarat, India) (Nidhi Lohani, Soumyajit Mukherjee, Seema Singh, Aashu Pawar, Mohamedharoon Shaikh) -- Chapter 8 - Structural and sedimentary field studies in Angul District, Odisha, India (Subhajit Sinha, Ananya Ghosh, Somnath Mishra) -- Chapter 9 - New Structural geological input from the Barmer Basin, Rajasthan (India) (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Swagato Dasgupta, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 10 - Structural geology and stability issue of the Giral lignite mine, Rajasthan, India (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 11 - Relationship between deformation structures and rock mass rating: A case study of underground power house, Andhra Pradesh- India (Mohit Kumar Puniya, Sohan Kumar, Ashish Kumar Kaushik, Nikhil Puniya) -- Chapter 12 - Macrostructures mimic Meso-structures (Harsh Bhu, Ritesh Purohit, Riya Dutta) -- Chapter 13 - Review on Role of multi-constellation Global Navigation Satellite System-Reflectometry (GNSS-R) for real-time sea-level measurements (Kutubuddin Ansari) -- Chapter 14 - Architecture and structures of Kiradu temple (Barmer region, Rajasthan, India) (Paramita Haldar,, Mohit Kumar Puniya, Mery Biswas, Soumyajit Mukherjee, Nihar Ranjan Kar, Ratna Choudhary).
    Abstract: This book is the second volume of an edited work aiming to help novice geologists to explore terrains independently. Geoscience fieldwork with focus on structural geology and tectonics has become more important in the last few years from both academic and industrial perspectives. This book also works as a resource material for batches of students or geological survey professionals undergoing training as parts of their course curriculum/training. Industry persons, on the other hand, can get a first-hand idea about what to expect in the field, in case no academic persons are available with the team. This book focuses on structural geology and tectonics and compiles terrains from several regions of the globe. This book also includes field guide chapters for primary sedimentary structures.
    Type of Medium: Online Resource
    Pages: XVI, 418 p. 323 illus., 304 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031195761
    Series Statement: Springer Geology Field Guides, FieldGuides,
    URL: https://doi.org/10.1007/978-3-031-19576-1
    DOI: 10.1007/978-3-031-19576-1
    DDC: 551
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    Water Resources of Pakistan : Issues and Impacts (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Water. ; Hydrology. ; Geology. ; Water.
    Description / Table of Contents: Chapter 1 Pakistan’s Water Resources: Overview and Challenges -- Chapter 2 Pakistan’s Water Resources: From Retrospect to Prospect -- Chapter 3 Pakistan’s Transboundary Water Challenge -- Chapter 4 Water Security in Pakistan: Availability, Accessibility and Utilisation -- Chapter 5 Climate Change in the Mountains of Pakistan and its Water Availability Implications -- Chapter 6 Pakistan’s Water Resources in the Era of Climate Change -- Chapter 7 Unlocking Economic Growth Under a Changing Climate: Agricultural Water Reforms in Pakistan -- Chapter 8 Sustainability Analysis of Irrigation Water Management in Punjab -- Chapter 9 Examining Irrigated Agriculture in Pakistan with a Water-Energy-Food Nexus Approach -- Chapter 10 Groundwater Crisis: a Crisis of Governance? -- Chapter 11 Spatial Variability of Groundwater Storage in Pakistan -- Chapter 12 Impacts of Water Quality on Human Health in Pakistan -- Chapter 13 Improving Water Management in Pakistan using Social-Ecological Systems Research -- Chapter 14 A Roadmap for a Comprehensive Water Resources Forecast System for Pakistan -- Chapter 15 Ways Forward to Improve Water Security in Pakistan.
    Abstract: This book presents the first comprehensive assessment of water resources in Pakistan including surface water resources and groundwater resources. It gives a detailed overview of issues and challenges related to water which have not been adequately addressed e.g. water resource vulnerability to climate change, groundwater depletion and contamination, and water governance etc. It includes a collection and compilation of unpublished and scattered data from the archives and repositories of various national institutions and organization. Given the literature dearth, this book will not only be a comprehensive assessment of water resources in Pakistan but can also can as outstanding textbook on water resource management in Pakistan. It will attract a great range of readership including water specialists, researchers, undergraduate and post graduate students and policy makers from Pakistan as well as from overseas.
    Type of Medium: Online Resource
    Pages: XVI, 318 p. 72 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030656799
    Series Statement: World Water Resources, 9
    URL: https://doi.org/10.1007/978-3-030-65679-9
    DOI: 10.1007/978-3-030-65679-9
    DDC: 551
    Language: English
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  • 60
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    Groundwater in Egypt’s Deserts (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Sustainability. ; Energy policy. ; Energy and state. ; Geophysics. ; Geochemistry. ; Geology. ; Sustainability. ; Energy Policy, Economics and Management. ; Geophysics. ; Geochemistry.
    Description / Table of Contents: Overview of the Egyptian Deserts' Ground Water Resources and Their Qualities -- Fault zone hydrogeology and structural control on groundwater flow in the Egyptian aquifers -- Hydrogeology and Waterlogging problem in Egypt's Deserts, Case Study: Abu Meina Archaeological site , Burg Al-Arab -- Conceptual Models for Groundwater Management in Egypt's Deserts -- Characterizing ecosystem services to human well-being in groundwater dependent desert environments.
    Abstract: This book brings together contributions from groundwater researchers and scientists on underground water resources in Egypt's deserts. The aquifers' quantity and quality are evaluated in many regions of the Egyptian deserts using established methods that can be effectively employed to investigate the potential for sustainable development in Egypt and similarly arid countries. The water resources in Egypt's deserts are subject to deterioration, mainly by land salinization and water deficiency. This book presents the best management practices, water quantity and quality, and optimal and sustainable usage of available groundwater. The book offers a unique guide for all readers interested in groundwater, modeling, and assessment for sustainable development in Egypt and countries with similar weather and water conditions. .
    Type of Medium: Online Resource
    Pages: X, 442 p. 178 illus., 162 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030776220
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-77622-0
    DOI: 10.1007/978-3-030-77622-0
    DDC: 551
    Language: English
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  • 61
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    Heat-Mass Transfer and Geodynamics of the Lithosphere (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Thermodynamics. ; Heat engineering. ; Heat transfer. ; Mass transfer. ; Natural disasters. ; Geotechnical engineering. ; Geology. ; Engineering Thermodynamics, Heat and Mass Transfer. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Preface -- The processes of heat and mass transfer in the Earth's mantle -- Thermo-gravity model for sedimentary basins -- Prospects for identifying and applied use of hydro and petrothermal energy sources in geodynamically active structures of the eastern segment of the Central Caucasus -- Models of geothermal areas: new insights from electromagnetic geothermometry -- Explosive processes in permafrost areas - new type of geocryological hazard -- Borehole temperature measurements under free thermal convection -- Geothermal regime of groundwater in Moscow under anthropogenic impact -- Geothermy of the continental margins of Eastern Russia -- Geothermal evidence of cyclic back-arc spreading in the marginal seas of the North-West Pacific -- Heat flow asymmetry on the mid-oceanic ridges of northern and southern earth hemispheres -- The correlation between Earth heat flow and oil and gas potential – fundamental pattern of Western Siberia -- Influence of hydrodynamic conditions on the mass transfer of pollutants in the areas of liquidated mines -- Factor modeling of mass transfer of pollutants in the areas of hydrogeological windows -- Hydraulic fracture problem for poroelastic medium with double porosity -- Incompletely coupled equations of hydraulic fracturing in poroelastic medium -- Geomechanical model for large scale hydraulic fracture dynamics -- Thermodynamic properties of geothermal fluids from South Russiai Kayakent and Kizlyar hot sources -- Thermodynamic properties of geothermal fluids from South Russia: Izberbash and Thernair hot sources -- ROSA Database and GIS Project: accumulation of the world largest oil and gas deposits in geological history -- Lithosphere of the West Transbaikalian sector of the Central Asian fold belt according to electromagnetic studies -- Caucasian-Arabian segment of Alpine-Himalayan convergence: an example of continental collision above mantle plume -- Geothermics and seismicity of the Caucasus region and the inverse problem of geodynamics -- Geothermics and geodynamics of the back-arc basins of the Alpine and Pacific belts -- Structure and dynamics of the lithosphere for the Eurasia-Pacific transition zone -- Recognition of Strong Earthquake–Prone Areas with a Single Learning Class Caucasus, М ≥ -- Evaluation of the influence of soils resonant properties during seismic microzoning work -- Seismotectonic model of the western margin of the South American Plate -- Permeability of the Continental Crust –Possible High Values from Laboratory Measurements and Seismological Data -- Endogenous and exogenous manifestations of geodynamic activity in the Central Caucasus.
    Abstract: This volume is devoted to investigation of all aspects of heat-mass transfer processes at different scales and from various origins, as well as the formation and evolution of geological structures. These phenomena are linked to geophysical properties of rocks, geothermal resources, geothermics, fluid dynamics, stress-state of the lithosphere, deep geodynamics, plate tectonics, and seismicity, among others. The book consists of two main parts. The first concerns heat-mass transfer associated with natural and technogenic processes in the upper lithosphere. The second deals with geodynamics and seismicity. The collection of over 25 chapter from leading investigators in Russia is thus an important contribution to research on the lithosphere in connection with formation and evolution of geological structures; heat and mass transfer processes in the lithosphere and their connection with deep Earth geodynamics. Collects a range of research methodologies including application of modelling, seismic tomography, geological field works, geological-geophysical methods, and in situ measurements through instrumentation; Explains how a wide range of geological and geophysical phenomena arising in the Earth’s lithosphere can be investigated under the umbrella of a common approach to heat-mass transfer processes; Includes the latest research by more than 60 leading scientists from Russia.
    Type of Medium: Online Resource
    Pages: X, 549 p. 205 illus., 149 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030635718
    Series Statement: Innovation and Discovery in Russian Science and Engineering,
    URL: https://doi.org/10.1007/978-3-030-63571-8
    DOI: 10.1007/978-3-030-63571-8
    DDC: 551
    Language: English
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    Ecological Tourism in the Republic of Kazakhstan (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Cultural property. ; Archaeology. ; Conservation biology. ; Ecology . ; Geology. ; Heritage Management. ; Conservation Biology.
    Description / Table of Contents: 1. Scientific and Methodological Basis of the Ecological Tourism Development -- 2. The Natural and Recreational Potential of Kazakhstan for the Ecological Tourism Development -- 3. Social and Economic Tourism Potential of Kazakhstan -- 4. Potential Geoparks of Kazakhstan -- 5. Evaluation of Tourist-Resource Potential On Ecological Tourism At Scale Of Kazakhstan Regions -- 6. Current State and Prospects for The Ecological Tourism Development of Kazakhstan -- 7. Conclusion -- 8. References.
    Abstract: This book analyses the theoretical and methodological foundations of ecotourism and geotourism and examines the essence, content, factors, and models of ecotourism development. The authors conducted research to assess the tourist and recreational potential of ecotourism in Kazakhstan. The study analyses the current state and describes the problems of the long-term development of ecotourism. Besides, the authors also show the role of specially protected natural areas in ecotourism development, including a list of organizations that can create tourist products in the environmental direction. This book also defines the primary conditions necessary for ecotourism in protected natural and rural areas. The resulting cartographic material visualizes the geospatial potential of the regions of Kazakhstan, aiming a more targeted expenditure of financial resources allocated to tourism development. Thus, the presented book is relevant from a practical perspective to scientists and researchers and is of value to business structures and stakeholders.
    Type of Medium: Online Resource
    Pages: VIII, 281 p. 113 illus., 108 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030774622
    URL: https://doi.org/10.1007/978-3-030-77462-2
    DOI: 10.1007/978-3-030-77462-2
    DDC: 551
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  • 63
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    Geodynamics of the Indian Plate : Evolutionary Perspectives (2020)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Geomorphology. ; Physical geography. ; Geochemistry. ; Geography. ; Geology. ; Geomorphology. ; Earth System Sciences. ; Geochemistry. ; Regional Geography.
    Description / Table of Contents: Chapter1. Introduction -- Chapter2. Evolving Early Earth: Insights from Peninsular India -- Chapter3. Tracking India within Precambrian supercontinent cycles -- Chapter4. Proterozoic Sedimentary basins of India -- Chapter5. Oxygenation of early atmosphere and potential stratigraphic records from India -- Chapter6. Early life from the Proterozoic sedimentary basins of India -- Chapter7. Geodynamics of Gondwanaland -- Chapter8. Cretaceous Volcanism in Peninsular India: Rajmahal_Sylhet, Deccan Traps -- Chapter9. Phanerozoic Mass Extinctions and Indian Stratigraphic Records -- Chapter10. Geological Evolution of the Himalayan Mountains -- Chapter11. Cenozoic Himalayan foreland basin: an overview and regional perspective of the evolving sedimentary succession -- Chapter12. Active tectonics of Himalayan frontal fault zone in the Sub Himalaya -- Chapter13. Late Quaternary evolution and morphostratigraphic development of the Ganga Plains -- Chapter14. Evolution and development of the Indian Monsoon -- Chapter15. Climate Change over the Indian sub-continent.
    Abstract: This book provides insights on new geological, tectonic, and climatic developments in India through a time progression from the Archean to the Anthropocene that are captured via authoritative entries from experts in earth sciences. This volume aims to bring graduate students and researchers up to date on the geodynamic evolution of the Indian Plate; concepts that have so far resulted in a rather uneven treatment of the subject at different institutions. The book is divided into 4 sections and includes perspectives such as the formation and evolution of the Indian crust in comparison to its neighbors such as Antarctica, Africa and Australia; the evolution of Precambrian cratons and sedimentary basins of India; and a summary account of early life reported in the Indian stratigraphic record. Readers will also discover the key recent research into the neotectonics, tectonic geomorphology, and paleoseismology of the Himalayan Front. Researchers and students in geology, earth sciences, sedimentology, paleobiology and geography will find this book appealing.
    Type of Medium: Online Resource
    Pages: VIII, 574 p. 173 illus., 139 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030159894
    Series Statement: Springer Geology,
    URL: https://doi.org/10.1007/978-3-030-15989-4
    DOI: 10.1007/978-3-030-15989-4
    DDC: 551
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    Water Resources of Italy : Protection, Use and Control (2020)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Water. ; Hydrology. ; Pollution. ; Environment. ; Sustainability. ; Geology. ; Water. ; Pollution. ; Environmental Sciences. ; Sustainability.
    Description / Table of Contents: 1. Preface -- 2. Part I - Evolution of water management in Italy -- 3. Chapter 1. Italy’s outline M. Benedini -- 4. Chapter 2. Paradigm changes in water resources development G. Rossi -- 5. Chapter 3. Water Legislation: main innovation principles on water resources uses, pollution control and flood risk mitigation, G. Rossi -- 6. Chapter 4. Institutional framework of water governance: planning, service management and soil defense) G. Rossi -- 7. Part II - Water resources and water demands -- 8. Chapter 5. Conventional water resources (Surface and ground water resources) G. Rossi, M. Benedini -- 9. Chapter 6. Unconventional water resources (desalinated waters and treated wastewater reuse) G. Rossi, G. Cirelli -- 10. Chapter 7. Assessment of water requirements (domestic and urban uses; agricultural uses; industrial uses, navigation…) M. Benedini, R. Drusiani -- 11. Part III - Problems -- 12. Chapter 8. Management of municipal water services M. Di Natale, G. Rossi -- 13. Chapter 9. Water pollution control M. Benedini -- 14. Chapter 10. Water and electric power G. Ruggeri, M. Benedini -- 15. Chapter 11. Ecological in-stream flows (or water and environment) S. Alecci, G Rossi -- 16. Part IV – Challenges -- 17. Chapter 12. Mitigation of flood risk G. Rossi -- 18. Chapter 13. Coping with droughts G. Rossi -- 19. Chapter 14. Virtual water F. Laio, S. Tamea, M. Tuminetti -- 20. Chapter 15. Adaptations strategies to climate change in water resources D. Peres -- 21. Part V – Conclusions -- 22. Chapter 16. The future of water management in Italy M. Benedini, G. Rossi. .
    Abstract: This book offers a comprehensive framework of the current state of water resources in Italy and of the main stages of the evolutionary way in the last decades for achieving an integrated, sustainable and equitable water resources management. The main paradigms of water resources development are identified as: i) engineering and economic approach to water resources exploitation, ii) focus on pollution control and water-excess management, iii) a comprehensive approach toward a sustainable and equitable distribution of resources and effective risk reduction of water-related disasters. After a section devoted to the analysis of some historic stages in the legislation framework and the governance of water and soil, with particular reference to planning, design, building and operation of water systems, two sections deal with the estimation of water resources availability on national territory and estimation of water demands in municipal, agricultural, industrial, ecosystem sectors. The complex problems that the Italian society has to solve in the water field and the main challenges of a changing world are discussed in the fourth section of the volume. The book will not only be useful for water professionals, but also for citizen who like to discern the key factors which delay the recognition of water as a resource for life. The description of the problems and adopted solutions could also serve as a guideline for similar situations encountered in other countries, improving the preparation of the responsible people.
    Type of Medium: Online Resource
    Pages: XVII, 365 p. 97 illus., 80 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030364601
    Series Statement: World Water Resources, 5
    URL: https://doi.org/10.1007/978-3-030-36460-1
    DOI: 10.1007/978-3-030-36460-1
    DDC: 551
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    The Geoheritage of Hot Springs (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Conservation biology. ; Ecology . ; Geophysics. ; Physical geography. ; Geology. ; Conservation Biology. ; Geophysics. ; Earth System Sciences.
    Description / Table of Contents: Hot springs: A general perspective -- The geology of hot springs -- The geochemistry of hot springs -- The conservation of hot springs -- Hot springs throughout history -- Hot springs and their cultural heritage.
    Abstract: The aim of this book is to provide an overview of topics related to the extensive geoheritage of hot springs, their natural environments, and their integration into commercial and industrial functions. The eleven chapters explore aspects of historical and cultural traditions, geology and geochemistry, research updates, conservation issues and of course health, wellness, and recreation throughout time. Because natural hot springs and active hydrothermal areas play a significant role in the tourism industry, visitor expectations are examined together with an assessment of common hazards and potential risks in active hydrothermal environments, along with recommendations how to stay safe. For the purpose of showcasing certain unique features, to share noteworthy events and developments or to identify concerns associated with the sustainability of natural water source, examples of particular hot spring areas are included in several chapters. One chapter is also dedicated entirely to the protection of natural hot springs and raises awareness for conservation, while another chapter reviews the history of hot springs in great detail to establish a realistic and justifiable timeline of their original use. Lastly, the significance of natural hot springs for various tourism sectors is analysed and the potential for sustainable future destination development in rural and remote regions is discussed. Many locations were considered and invite the reader to use the information as a reference point in the quest to further explore the remarkable natural and cultural geoheritage of hot springs worldwide.
    Type of Medium: Online Resource
    Pages: XL, 383 p. 289 illus., 248 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030604639
    Series Statement: Geoheritage, Geoparks and Geotourism, Conservation and Management Series,
    URL: https://doi.org/10.1007/978-3-030-60463-9
    DOI: 10.1007/978-3-030-60463-9
    DDC: 551
    Language: English
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    Geological Resources of Tierra del Fuego (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Physical geography. ; Mineralogy. ; Geology. ; Earth System Sciences. ; Mineralogy.
    Description / Table of Contents: Chapter 1. An introduction to the geology of Tierra del Fuego -- Chapter 2. Beatriz Mine: a Polymetallic Massive Occurrence in Tierra del Fuego -- Chapter 3. A review of the Arroyo Rojo VMS deposit, Tierra del Fuego -- Chapter 4. The Ornamental Rocks of Tierra del Fuego -- Chapter 5. Aggregates in Tierra del Fuego: Morphogenesis and Distributio -- Chapter 6. Didactic Tools in the Scope of Geography in the Provincia de Tierra del Fuego -- Chapter 7. Teaching Earth Sciences in the Provincial Educational System -- Chapter 8. History of Gold in Tierra del Fuego -- Chapter 9. Isla Grande de Tierra del Fuego and Isla de los Estados Peatlands -- Chapter 10. Lakes and Glaciers from Fuegian Andes. Morphology, Distribution and Origin -- Chapter 11. Geophysical Methods Applied to the Study of Lakes and Paleolakes in Tierra del Fuego -- Chapter 12. Geological and Geographic Resources among Hunter-gatherers of Tierra del Fuego: a View from Archaeological and Ethnographic Data -- Chapter 13. Geotourism – Interpretation – Ethnogeology: Extraordinary Geological Resources in Tierra del Fuego -- Chapter 14. Key features and Geosite proposal to tell the story of the Argentinian Andes in the Isla Grande de Tierra del Fuego -- Chapter 15. Differential Uplifting Rates Across the Magellan Fault: Interactions Between South American and Scotia Plates -- Chapter 16. Paleomagnetic and Magnetic Studies of Quaternary Units in Tierra del Fuego, the South Atlantic Islands and Southern Patagonia -- Chapter 17. Provenance of the Coastal Sands of the Western Scotia Plate: Tierra del Fuego and Antarctic Peninsula -- Chapter 18. An overview on the Mineral Resources of the Argentine Antarctic Sector -- Chapter 19. Meteorites found in the Argentine Antarctic Sector -- Chapter 20. Acidity and Alkalinity as Foundational Parameters in the Ordering of Eruptive Rocks and some Fuegian examples.
    Abstract: The CADIC’s Geological Resources Program will soon turn 40 years of fruitful development. During this period many projects were carried out and others remain to be implemented. In the course of time three generations of researchers have been formed. Mentioning names would be unfair to those that could be involuntarily omitted. There is still a long way to go. The eagerness for knowledge should not stop. This book is a tribute to all those people who have worked in the different projects of pure and applied science, and educational, and human resources training, granted to this founding program and associated laboratories of the regional center of CONICET in Ushuaia, Tierra del Fuego, Argentina. The twenty papers which constitute this book have a genuine Latin appeal, having been written by 50 authors based in Argentina and Spain. All this contributions are concerned with Fuegian geological resources. Everyone concerned with this work hopes that it will prove a fitting and lasting memorial to Nacho Subías, whose personal contribution to our knowledge of this geology was outstanding.
    Type of Medium: Online Resource
    Pages: XII, 371 p. 173 illus., 136 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030606831
    Series Statement: Springer Geology,
    URL: https://doi.org/10.1007/978-3-030-60683-1
    DOI: 10.1007/978-3-030-60683-1
    DDC: 551
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    Disaster Risk Reduction in Mexico : Methodologies, Case Studies, and Prospective Views (2021)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Geotechnical engineering. ; Emergency medical services. ; Industrial Management. ; Political science. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences. ; Emergency Services. ; Industrial Management. ; Governance and Government.
    Description / Table of Contents: Preface -- Before the Disaster -- During the Disaster -- After the Disaster -- Ways to Create Resilience in the Economic Activities.
    Abstract: This book recognizes Mexico's effects and challenges in a natural disaster and offers empirical risk-reduction methods in critical cases. The proposals considered here include real and detailed analysis, a set of models, frameworks, strategies, and findings in the three stages of the disaster (before–during–after). This book: describes the methodology to find secure locations for the Regional Humanitarian Response Depot; offers recommendations for the sites and creation of an Export Logistics Cluster; shows how to use available technology and information to locate volunteers in the right spots describes mathematical models to help to allocate procedure of resources for restoring the affected community and proposes actions to create resilience in the country's main economic sectors, including agriculture and industry. The processes applied at recent disasters such as the 19S earthquake and their results are used as case studies, identifying possibilities for further improvement. The book also describes new trends for Mexico due to climate change and makes suggestions for mitigating future disasters. The proposals are also replicable to other highly populated societies with similar socio-economic structures. Finally, this book is the basis for generating more innovative recommendations by researchers, graduate students, academics, professionals, and practitioners to obtain better planning and better collaboration between all the humanitarian chain actors. This book intends to be of interest as a fundamental tool for decision-makers, governments, non-governmental organizations, and enterprises.
    Type of Medium: Online Resource
    Pages: XII, 380 p. 108 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030672959
    URL: https://doi.org/10.1007/978-3-030-67295-9
    DOI: 10.1007/978-3-030-67295-9
    DDC: 551
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    The Geology of Iran: Tectonic, Magmatism and Metamorphism (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geomorphology. ; Sedimentology. ; Geology. ; Geomorphology. ; Sedimentology.
    Description / Table of Contents: Geological setting and crustal structure of Iran -- Structural units of Iran -- Faults and Tectonic Phases of Iran -- Magmatic Phases and their Distribution in Iran -- Intrusive Rocks of Iran -- Ophiolite Complexes in Iran -- Metamorphic Rocks of Iran.
    Abstract: This book describes the geological setting of Iran throughout geological history, referring to paleogeography and general geodynamics. Also, all structural units, faults, tectonic phases and orogeny occurred in the geology of Iran have been evaluated. Magmatic and metamorphic rocks along with ophiolitic complexes have extensive outcrops in Iran, and these rocks with Precambrian age constitute its basement. Study and identification of such rocks not only throws light on the geodynamic issues of Iran but also helps in recognition of the mode of formation and evolution of the sedimentary basins located within various structural divisions of the country. Moreover, the majority of metallic and non-metallic mineral deposits are associated either directly or indirectly with magmatic, and at time metamorphic, rocks. In the Magmatism and Metamorphism parts, it is tried to thoroughly consider the various aspects of the igneous rocks, whether intrusive, extrusive or young volcanoes, from the point of view of petrography, geochemistry and geodynamics. In addition, the major intrusive bodies of Iran have been presented along with their petrologic and chronologic specifications in tables, mentioning the bibliographic resources.
    Type of Medium: Online Resource
    Pages: XII, 441 p. 134 illus., 96 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030711092
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-030-71109-2
    DOI: 10.1007/978-3-030-71109-2
    DDC: 551
    Language: English
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    Wildland Fire Smoke in the United States : A Scientific Assessment (2022)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Fire ecology. ; Forestry. ; Pollution. ; Biology. ; Earth sciences. ; Geography. ; Natural Hazards. ; Fire Ecology. ; Forestry. ; Pollution. ; Biological Sciences. ; Earth and Environmental Sciences.
    Description / Table of Contents: Chapter 1. Assessing the State of Smoke Science -- Chapter 2. Fuels and Consumption -- Chapter 3. Fire Behavior and Heat Release as Source Conditions for Smoke -- Chapter 4. Smoke Plume Dynamics -- Chapter 5. Emissions -- Chapter 6. Smoke Chemistry -- Chapter 7. Social, Economic, and Health Effects of Smoke -- Chapter 8. Resource Manager Perspectives on the Need for Smoke Science -- Appendix A: Regional Perspectives on Smoke Issues and Management -- Appendix B: Smoke Monitoring Networks, Models, and Mapping Tools.
    Abstract: This open access book synthesizes current information on wildland fire smoke in the United States, providing a scientific foundation for addressing the production of smoke from wildland fires. This will be increasingly critical as smoke exposure and degraded air quality are expected to increase in extent and severity in a warmer climate. Accurate smoke information is a foundation for helping individuals and communities to effectively mitigate potential smoke impacts from wildfires and prescribed fires. The book documents our current understanding of smoke science for (1) primary physical, chemical, and biological issues related to wildfire and prescribed fire, (2) key social issues, including human health and economic impacts, and (3) current and anticipated management and regulatory issues. Each chapter provides a summary of priorities for future research that provide a roadmap for developing scientific information that can improve smoke and fire management over the next decade.
    Type of Medium: Online Resource
    Pages: XVI, 341 p. 63 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030870454
    URL: https://doi.org/10.1007/978-3-030-87045-4
    DOI: 10.1007/978-3-030-87045-4
    DDC: 551
    Language: English
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    Mars: A Volcanic World (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Astronomy. ; Earth sciences. ; Geochemistry. ; Geology. ; Astronomy, Cosmology and Space Sciences. ; Earth Sciences. ; Geochemistry.
    Description / Table of Contents: Chapter 1 - History of scientific studies and current views of Mars -- Chapter 2 - The formation of Mars and the origin of its volcanic provinces -- Chapter 3 - Petrologic evolution of Martian volcanism and clues from meteorites -- Chapter 4 - Volcanic eruptions on Mars, lava flow morphology, and thermodynamics -- Chapter 5 - Volcanic Channels and Volcanic Features on Mars -- Chapter 6 - General concepts on porous-media flow on Mars – thermal H2O-CO2-fers – -- Chapter 7 - Buried volcano-hydrothermal systems and minerals on Mars -- Chapter 8 - Explosive volcanism on Mars -- Chapter 9 - The origin and evolution of volcanism at Martian highland paterae: A review of the current state of knowledge -- Chapter 10 - Infrasound Propagation on Mars atmosphere -- Chapter 11 - Potential Futures in Human Habitation of Martian Lava Tubes -- Chapter 12 - Future perspectives of Mars after the latest studies.
    Abstract: This book is a comprehensive advancement about the understanding of the volcanology of Mars in all its aspects, from its primary formation to its evolution in time, from the smaller structures to the bigger structures. It discusses the implications of volcanism in the general environmental and geological context of Mars. The book is validating the Southern Giant Impact Hypothesis explaining the formation of Mars in an interdisciplinary approach, including mineralogical, geochemical, volcanological as well as geomorphological information. Implications for future explorations in terms of resources are provided. This book serves as a textbook for undergraduate and graduate level to foster new basic research in the field of planetary volcanology and is a new guide for future missions toward a volcanic world, including new detailed information for the general audience who is always keen to know more about the history of Mars and its large volcanoes. The book also presents an updated situation about the water resources of the planet.
    Type of Medium: Online Resource
    Pages: VIII, 327 p. 138 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030841034
    URL: https://doi.org/10.1007/978-3-030-84103-4
    DOI: 10.1007/978-3-030-84103-4
    DDC: 551
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    Problems of Geocosmos–2020 : Proceedings of the XIII International Conference and School (2022)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Solar system. ; Astronomy. ; Environmental sciences. ; Physics. ; Geology. ; Space Physics. ; Astronomy, Cosmology and Space Sciences. ; Environmental Physics.
    Abstract: This book addresses the problems of Geocosmos and provides a snapshot of the current research in a broad area of Earth Sciences carried out in Russia and elsewhere. The themes covered include solar physics, physics of magnetosphere, ionosphere and atmosphere, solar-terrestrial coupling links, seismology, geoelectricity, paleomagnetism and rock magnetism, as well as cross-disciplinary studies. The proceedings are carefully edited, providing a panoramic outlook of a broad area of Earth Sciences. The readership includes colleague researchers, students and early career scientists. The proceedings will help the readers to look at their research fields from various points of view. Problems of Geocosmos conferences are held by Earth Physics Department, St. Petersburg University bi-annually since 1994. It is the largest forum of this kind in Russia/former Soviet Union attracting up to 200 researchers in Earth and magnetospheric physics.
    Type of Medium: Online Resource
    Pages: XII, 495 p. 235 illus., 188 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030914677
    Series Statement: Springer Proceedings in Earth and Environmental Sciences,
    URL: https://doi.org/10.1007/978-3-030-91467-7
    DOI: 10.1007/978-3-030-91467-7
    DDC: 551
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    Disaster Management in the Complex Himalayan Terrains : Natural Hazard Management, Methodologies and Policy Implications (2022)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Geomorphology. ; Geography. ; Physical geography. ; Geographic information systems. ; Natural Hazards. ; Geomorphology. ; Geography. ; Physical Geography. ; Geographical Information System.
    Description / Table of Contents: Part-A: Introduction to the Disasters and Hazards in the Himalayan Terrains -- 1. Disasters in the Complex Himalayan Terrains -- 2. Hazards in the perspective of Himalayan Terrain: A review -- Part-B: Landslides in the Himalayas – Causes and Consequences -- 3. Himalayan Landslides – Causes and Evolution -- 4. Landslides in the Himalayas: Causes, Evolution, and Mitigation – A Case Study of National Highway 44, India -- 5. Geo-environmental Impact of Road Widening Project along the National Highway- 44A, Jammu & Kashmir, India -- Part-C: Floods in the Himalayas – Causes and Consequences -- 6. September 2014 floods in Kashmir Himalaya - Impacts and Mitigation Strategy -- 7. A review on the estimation of Glacial Lake Outburst Floods (GLOFs) in the Himalayan region using remote sensing and geographic information system -- 8. Impact of Floods on the Green Energy Sector in the Himalayas using remote sensing and geographic information system (GIS) – A case study of Gagas Watershed, Uttarakhand, India -- Part-D: Earthquakes in the Himalayas – Assessment and Forecasting -- 9. Synthetic Aperture Radar Interferometry to Measure Earthquake Related Deformation: A Case Study from Nepal -- 10. Earthquake Forecasting in the Himalayas using Artificial Neural Networks -- Part-E: Hazard mitigation strategies in the Himalayas -- 11. Forest Fire Alert System of India with a Special Reference to Fire Vulnerability Assessment of the UT of Jammu and Kashmir -- 12. Hazard mitigation and climate change in the Himalayas – Policy and Decision making.
    Abstract: South Asia, harboring the complex Himalayan terrains, has over one-fifth of the world’s population and is recognized as the most hazard-prone region of the world. The exponential increase in population with the consequent pressure on natural resources and continued high rates of poverty and food insecurity also makes this region the most vulnerable region to hazards in the world as far as the impacts of climate change are concerned. Over the last century, the climatic trends in South-Asia have been observed to be characterized by increasing air temperatures and an increasing trend in the intensity and frequency of extreme events. IPCC (2014) has reported that the Himalayan highlands shall face significant warming over the next century. The increasing frequency of natural hazards due to the impacts of climate change in the Himalayas calls for efficient management and policymaking in these regions, which can only be implemented by the local governments through an established science-based robust action plan. This edited volume focuses on the management of natural hazards using innovative techniques of spatial information sciences and satellite remote sensing. It contains chapters from eminent researchers and experts in the field of hazard management, remote sensing, and GIS. The primary focus of this book is to replenish the gap in the available literature on the subject by bringing the concepts, theories, and practical experiences of the specialists and professionals in this field together in one volume to help students, researchers, and policymakers to address issues concerning management and policy implications of natural hazards in the complex Himalayan region.
    Type of Medium: Online Resource
    Pages: XI, 182 p. 76 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030893088
    Series Statement: Geography of the Physical Environment,
    URL: https://doi.org/10.1007/978-3-030-89308-8
    DOI: 10.1007/978-3-030-89308-8
    DDC: 551
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    Urban Design in Seismic-Prone Regions (2022)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Engineering design. ; Natural Hazards. ; Engineering Design.
    Description / Table of Contents: Urban design and natural disasters -- Definitions and concepts -- Manjil earthquake of June 20, 1990, lesson learned from experience -- Design at macro scale: Urban design in a seismic-prone city -- Urban design solutions to mitigate seismic risk at the small scale: Rasht city center -- Creating open spaces and modification of access networks--the case of the central area of the city of Rasht -- Urban design guidelines in the seismic-prone regions -- Conclusion -- Epilogue: Natural disasters, sustainability, resilience, cities and Covid 19.
    Abstract: This book presents practical guidelines and recommendations for the design in seismic-prone regions. It is based on extensive research and it includes original drawings and sketches at the macro and micro levels. It is the first time that an attempt has been made to publish a book on urban design in the seismic-prone regions, covering the needs of government officials, planners, economists, architects, engineers and scientists, with the purpose of planning for seismic risk reduction and the practical implementation of method­ologies and findings in earthquake affected regions. The guidelines presented are expected to be immensely beneficial to all countries in the earth­quake prone regions, particularly in the developing world.
    Type of Medium: Online Resource
    Pages: X, 338 p. 257 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031083211
    Series Statement: The Urban Book Series,
    URL: https://doi.org/10.1007/978-3-031-08321-1
    DOI: 10.1007/978-3-031-08321-1
    DDC: 551
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    Recent Technologies for Disaster Management and Risk Reduction : Sustainable Community Resilience & Responses (2021)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Environmental management. ; Environmental monitoring. ; Natural Hazards. ; Environmental Management. ; Environmental Monitoring.
    Description / Table of Contents: Glacial lake outflow hazard and risk probability in Sikkim -- Rockfall Hazard Assessment using RAMMS for the SE Facing Escarpment of Manikaran, Himachal Pradesh, India -- Investigation of Indian Summer Monsoon Rainfall relationship with the Bay of Bengal sea surface temperature and currents -- A comparative study of interpolation methods for mapping soil properties: a case study of eastern part of Madhya Pradesh, India -- Geo Spatial application for coastal morphology changes along the sand mining coast: a case study on Alappad, Kerala.
    Abstract: This book explains to governments, decision makers and disaster professionals the potential uses of recent technologies for disaster monitoring and risk reduction based on the knowledge and experience of prominent experts/researchers in the relevant fields. It discusses the application of recent technological developments for emerging disaster risks in today's societies and deliberates on the various aspects of disaster risk reduction strategies, especially through sustainable community resilience and responses. This book consists of selected invited papers on disaster management, which focus on community resilience and responses towards disaster risk reduction based on experiences, and closely examines the coordinated research activities involving all stakeholders, especially the communities at risk. Many regions of the world and aspects of disaster risk and its management are covered. It is described how recent technologies will support better understanding and action to reduce the number and impact of disasters in future. The principal audience for this book is researchers, urban planners, policy makers, as well as students.
    Type of Medium: Online Resource
    Pages: XV, 479 p. 187 illus., 157 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030761165
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-030-76116-5
    DOI: 10.1007/978-3-030-76116-5
    DDC: 551
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    Disaster Risk Reduction for Resilience : Disaster Risk Management Strategies (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Industrial engineering. ; Production engineering. ; Geology. ; Emergency medical services. ; Natural Hazards. ; Environmental Social Sciences. ; Industrial and Production Engineering. ; Geology. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Global Standards for Disaster Risk Reduction -- Chapter 2. Guidelines for Resilient Disaster Risk Reduction: International Law Perspective -- Chapter 3. Strengthening Institutional Resilience: Lessons Learned from COVID-19 Disaster -- Chapter 4. Resilient and Effective Disaster Risk Management Index -- Chapter 5. Mining Hazard Risk Reduction and Resilience -- Chapter 6. Implementing Urban Resilience Strategies with Local Authorities -- Chapter 7. Land Use Planning and Green Infrastructure: Tools for Natural Hazards Reduction -- Chapter 8. Disaster Risk Management: A Resilient Health System -- Chapter 9. Coastal Erosion, Displacement and Resettlement Strategies -- Chapter 10. Resilience and Adaptation Strategies for Urban Heat at Regional, City and Local Scales -- Chapter 11. Combining Disaster Risk Reduction and Climate Change Adaptation for Greater Effectiveness: Lessons from Community-Level Interventions -- Chapter 12. Human Security in Times of Climate Change: Climate Diplomacy for Integrated Action -- Chapter 13. Case-Based Reasoning for Disaster Management: Structure Design for Cascading Disasters Case Base -- Chapter 14. Building Metropolitan Manila’s Institutional Resilience in the Context of Disaster Risk Reduction and Management -- Chapter 15. Exploring Disaster Risk Reduction Strategies In The Sahel: A Multi-Country Study of Burkina Faso, Chad, Mauritania, Niger and Senegal -- Chapter 16. Nexus Between Flooding, Water Quality and Cholera in Nigeria: A Review of Possible Public Health Interventions -- Chapter 17. Sustainable Smart City Planning using Spatial Data and Risk Reduction: A Case Study Siliguri Municipal Corporation -- Chapter 18. Social Representations and Climate Change Teaching in Trainee Social Sciences Teachers -- Chapter 19. Urban Vulnerability to Extreme Heat Events and Climate Change -- Chapter 20. Flooding in Informal Communities Residents’ Response Strategies to Flooding.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework, and provides additional resources, methodologies and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers and practitioners in engineering, environmental science and geography, geoscience, emergency management, finance, community adaptation, atmospheric science and information technology. This volume offers the international guidelines and global standards for resilient disaster risk reduction and lessons learned from disasters, particularly the COVID-19 and Cholera pandemics. A resilient health system and an effective disaster risk management Index are then suggested. The book further emphasizes urban resilience strategies with local authorities, adaptation strategies for urban heat at regional, city and local scales, and lessons from community-level interventions. Also addressed are coastal erosion, displacement and resettlement strategies. Land use planning and green infrastructure are suggested as tools for natural hazards reduction. Human security in times of climate change and urban heat at regional, city and local scales is discussed for an integrated action, with case studies based in Manila, Burkina Faso, Chad, Mauritania, Niger, Senegal, Nigeria, India, Spain, and Ghana. Structure design for cascading disasters resulting from mining and flooding is presented and sustainable smart city planning using spatial data is recommended.
    Type of Medium: Online Resource
    Pages: X, 473 p. 121 illus., 97 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030721961
    URL: https://doi.org/10.1007/978-3-030-72196-1
    DOI: 10.1007/978-3-030-72196-1
    DDC: 551
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    Disaster Risk Reduction for Resilience : Disaster and Social Aspects (2022)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Industrial engineering. ; Production engineering. ; Geology. ; Emergency medical services. ; Natural Hazards. ; Environmental Social Sciences. ; Industrial and Production Engineering. ; Geology. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Resilience Assessment at the State Level using the Sendai Framework -- Chapter 2. Disaster Recovery Reform and Resilience -- Chapter 3. Recovery, Development Programs and Place-Based Reconstruction Policy: A Flexible Framework -- Chapter 4. Recovery, Development Programs and Place-Based Reconstruction Policy: The Instrumental Role of Insurance -- Chapter 5. Development of Multi-Hazard Early Warning System in India -- Chapter 6. Cultural and Religious Aspects of Resilience: The Case of Typhoon Ketsana Victims in the Philippines -- Chapter 7. Building Socio-Ecological Resilience by Design for Flood-Prone Waterfront Cities: A Comparative Study of New Orleans of USA, Brisbane of Australia and Christchurch of New Zealand -- Chapter 8. Building Socio-Ecological Resilience against Drought: Case Study from Bhachau, Kachchh, Gujarat -- Chapter 9. Building Socio-Hydrological Resilience for Inclusion-Experience of Co-Operatives in Tanzania -- Chapter 10. Strengthening Climate Resilience and Disaster Risk Reduction: Case Study of the Sahel Adaptive Social Protection -- Chapter 11. Effect of Climate Change on Water Availability and Quality: An Assessment of Socio Resilience in Nigeria -- Chapter 12. A Risk Based Approach to Development Planning -- Chapter 13. Flood Risk Instruction Measures: Adaptation from the School -- Chapter 14. Flood Resilient Cities -- Chapter 15. Coastal Flood Prone Communities and Sustainability -- Chapter 16. Disaster Risk Reduction: Detecting Himalayan Glacial Lake Outburst Floods -- Chapter 17. Communities, Organizations and Partnerships for Climate Change Mitigation and Disaster Reduction -- Chapter 18. Coastal Wetland Hydrologic Resilience To Climatic Disturbances: Concept, Quantification, and Threshold Response -- Chapter 19. Perception of Vulnerable Ultra-Poor Women on Climate Change Impacts and Local Adaptation in a High Flood Prone Area of Bangladesh -- Chapter 20. Climate Change Adaptation and Resilience on Small-Scale Farmers.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework and provides additional resources, methodologies, and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers, and practitioners in engineering, environmental science, geography, geoscience, emergency management, finance, community adaptation, atmospheric science and information technology. This volume provides a holistic approach to developing disaster risk reduction strategies and policies, exploring the most effective ways to integrate physical and social science aspects of hazard resilience to better inform local populations. This risk-based approach to community resilience development is used to craft a collaborative system for crisis management, and allows for the implementation of nationally determined contributions (NDCs) through social innovation and community engagement to enhance community emergency response support and preparedness. Readers will also learn about education of disaster risk reduction, human health risk assessment, gendered perspectives in disaster response, recovery, and disaster management legislation.
    Type of Medium: Online Resource
    Pages: XIII, 473 p. 108 illus., 92 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030990633
    URL: https://doi.org/10.1007/978-3-030-99063-3
    DOI: 10.1007/978-3-030-99063-3
    DDC: 551
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    The Phanerozoic Geology and Natural Resources of Egypt (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Petrology. ; Paleontology . ; Earth sciences. ; Geology. ; Petrology. ; Paleontology. ; Earth Sciences.
    Description / Table of Contents: Overall paleogeographic and geodynamic evolution -- Major Groundwater reservoirs in Egypt -- Western Desert Petroleum sources and reservoirs -- Nile Delta Petroleum sources and reservoirs -- Gulf of Suez and Red Sea Petroleum sources and reservoirs -- Off-shore Mediterranean discoveries -- Petroleum Source Rocks of Egypt – An Integrated Palynological and Organic Geochemical Approach: Spatio-temporal studies within the Phanerozoic of Egypt -- Carbonate platform deposits and hydrocarbon potentiality -- Hydrocarbon seepage during the Messinian salinity crisis -- Rare Earth Element in Egypt -- Phanerozoic Stratabound/Stratiform Ore Deposits of Egypt.
    Abstract: The Phanerozoic Geology and Natural Resources of Egypt includes a series of chapters written by highly qualified group of researchers whose expertise is recognized and appreciated not only in Egypt, but also in the world over. The chapters span a wide range of geological subdisciplines including tectonics, paleogeography, stratigraphy, sedimentology, paleontology, groundwater, and energy resources, just to name a few. In this regard, the book provides the reader with ample knowledge about the different facets of the fascinating and always intriguing geology of Egypt since the Precambrian time. For a junior researcher or a geoscience student, the book is a comprehensive, multidisciplinary one-stop resource that they will continue to reference and rely on for years to come. For a more experienced scientist, the book summarizes the current state of knowledge, highlights the magnitude of complexity of the geology of Egypt and northeast Africa, and reveals potential areas where future research should be directed. The book is written in simple, easy to understand English language and contains very useful high-quality illustrations. Last but not least, The Phanerozoic Geology and Natural Resources of Egypt has been reviewed and edited by world class, highly ranked geoscientists from Egypt, Europe, and USA.
    Type of Medium: Online Resource
    Pages: XIX, 742 p. 593 illus., 529 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783030956370
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    URL: https://doi.org/10.1007/978-3-030-95637-0
    DOI: 10.1007/978-3-030-95637-0
    DDC: 551
    Language: English
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    Disaster Risk Reduction for Resilience : Climate Change and Disaster Risk Adaptation (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Physical geography. ; Environmental sciences Social aspects. ; Water. ; Hydrology. ; Emergency medical services. ; Natural Hazards. ; Earth System Sciences. ; Environmental Social Sciences. ; Water. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Linkage Between Social and Hydrological Systems to Support Resilience: A Case of Freshwater Wetland in Bangladesh -- Chapter 2. Indigenous Approaches to Disaster Risk Reduction, Community Sustainability and Climate Change Resilience -- Chapter 3. The Adaptation to Climate Change in the Primary Education and Approach from the Social Sciences Textbooks -- Chapter 4. Building Climate Change Adaptation and Risk Knowledge In the Arctic Through Preparedness and Contingency Practices -- Chapter 5. Ecological Resilience for Transformative Climate Change Mitigation and Adaptation -- Chapter 6. Mitigating Disaster Risks and Vulnerabilities through Climate Finance and Sustainable Water Management: Policy Considerations for Sub-Saharan Africa and Malawi -- Chapter 7. Assessing Risks and Resilience to Hydro-meteorological Disasters -- Chapter 8. Flood Resilient Plan for Urban Area: A Case Study -- Chapter 9. Flood and Drought Risk Assessment, Climate Change and Resilience -- Chapter 10. Flood Risk Predictions in African Urban Settlements: A Review of Alexandra Township, South Africa -- Chapter 11. Anthropological Study of a Typical Drought Prone Village in India- Strategies for Sustainable Rural Habitat -- Chapter 12. Risk Management of Extreme Precipitation in Mexico: Building Resilience -- Chapter 13. Increasing Temperature Risk and Community Resilience: Urban Aspects -- Chapter 14. Climate Change Adaptation and Sustainable Development -- Chapter 15. Climate Change, Food Security and Resilience: Hydrologic Excess and Deficit Measurement -- Chapter 16. Climate Change and Agro Forestry Resilience Strategy In West Africa’S Cocoa Supply Chain Dynamics -- Chapter 17. Spatial-Temporal Changes of Water Resources: Associated Impact as a Natural Hazard -- Chapter 18. Vulnerability of Climate Change on Water and Sanitation Sectors and Coping Mechanisms by the Communities of Economically Poor Hard to Rich Areas of Bangladesh -- Chapter 19. Climate Governance, Resilience and Enterpreneurship In Nigeria: An Empirical Review.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework, and provides additional resources, methodologies, and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers, and practitioners in engineering, environmental science and geography, geoscience, emergency management, finance, community adaptation, atmospheric science, and information technology. This volume offers indigenous approaches to disaster risk reduction, community sustainability and climate change resilience, as well as agro-ecological innovations for improving resilience to climate change. The focus is on adaptation strategies for sustainable terrestrial and marine ecosystems to reduce the impacts of anthropogenic factors that exacerbate disaster risk, including hydro-meteorological services for climate resilience, food security measures in agriculture and livestock, flood mitigation plans, and increased climate change education and awareness. The book concludes with three case studies in Africa detailing the impacts of strengthened climate change resilience measures, adaptive social protections, and improved water availability through hydro-electric technologies. .
    Type of Medium: Online Resource
    Pages: XVI, 457 p. 134 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031221125
    URL: https://doi.org/10.1007/978-3-031-22112-5
    DOI: 10.1007/978-3-031-22112-5
    DDC: 551
    Language: English
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  • 79
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    Space Weather Impact on GNSS Performance (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Environment. ; Industrial engineering. ; Production engineering. ; Geology. ; Environmental Sciences. ; Industrial and Production Engineering.
    Description / Table of Contents: Introduction -- GNSS Overview -- Space Weather General Concepts -- Methodology for GNSS Capability Analysis -- Experimental Results of GNSS/SBAS Performance Under Space Weather Impacts -- Real-Time Data Assimilation for Space Weather Effects Mitigation on GNSS/SBAS -- How to Improve GNSS/SBAS Reliability Under Space Weather Impacts: Analysis.
    Abstract: This book addresses problems of GNSS performance support under geomagnetic storms and solar radio bursts. It analyses both physical and radio-engineering sources of GNSS performance deterioration caused by geomagnetic storms, solar radio bursts and peculiarities of the polar and equatorial ionosphere. The book takes into consideration both standalone GNSS and differential GNSS. Based on experimental data analysis, it presents a systematic approach to maintaining reliable GNSS performance despite the Space Weather impacts. Given its scope, the book offers a valuable resource for GNSS users and equipment developers, as well as researchers and students whose work involves GNSS remote sensing, surveying, navigation, and related disciplines.
    Type of Medium: Online Resource
    Pages: XII, 368 p. 171 illus., 134 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031158742
    URL: https://doi.org/10.1007/978-3-031-15874-2
    DOI: 10.1007/978-3-031-15874-2
    DDC: 551
    Language: English
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  • 80
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    Solved Problems in Well Testing : Quantitative Geology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geotechnical engineering. ; Geophysics. ; Water. ; Hydrology. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Geophysics. ; Water.
    Description / Table of Contents: Introduction. The Premise of Well Tests -- Chapter 1. Qualitative Aspects: Pattern Recognition -- Chapter 2. Quantitative Aspects: Parameter Estimation -- Chapter 3. Special Cases of Gas and Gas Condensate Wells -- Chapter 4. Naturally Fractured Reservoirs -- Chapter 5. Hydraulically Fractured Wells -- Chapter 6. Horizontal Wells -- Chapter 7. Interference and Pulse Tests -- Chapter 8. Unconventional Wells -- Chapter 9. Injection Well tests -- Chapter 10. Drill Stem Tests -- Chapter 11. Pumping Well Tests -- Chapter 12. Geothermal Wells -- Chapter 13. Computer Aided Methods -- Chapter 14. Testing Water wells and Aquifers -- Chapter 15. Subsurfcae Fluid Disposal and Energy Storage -- Chapter 16. Designing Well Tests.
    Abstract: This book is about the technology of using fluid production or injection and pressure measurement signals from wellbores and relating those signals to the subsurface geology and subterranean reservoir properties. It is aimed at students of well-testing and practicing petroleum engineers or geoscience professionals for subsurface characterization and modeling. The topics include the art and science of well-test analysis, pattern recognition of rate and pressure signals, and a quantitative approach for estimating important subsurface geological parameters for subsurface aquifers and reservoirs containing oil, gas, and geothermal resources. The book is also particularly of value as a guide to asset managers actively developing unconventional reservoirs and CCUS.
    Type of Medium: Online Resource
    Pages: XVII, 191 p. 184 illus., 145 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031472992
    URL: https://doi.org/10.1007/978-3-031-47299-2
    DOI: 10.1007/978-3-031-47299-2
    DDC: 551
    Language: English
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    Enabling Adaptive Water Management to Face Drought Risk in a Changing Climate (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Water. ; Hydrology. ; Geography. ; Physical geography. ; Natural Hazards. ; Water. ; Regional Geography. ; Earth System Sciences.
    Abstract: This book explores the current challenges with regard to uncertainty and risk in water management, as well as the interlinkages between drought and water management. It focuses on the challenges for water management organisations, which are expected to adapt to such changes and implement adaptive water management. The book proposes a methodology for assessing organisations’ adaptive capacity, named REACT, and demonstrates its application in a case study. It subsequently analyses the barriers hindering water management organisations’ ability to adapt, and investigates the socio-cultural and economic barriers in water governance to applying adaptive water management (AWM) strategies. Lastly, the book describes how to enable AWM in order to face current and future drought risks by integrating it with drought risk management. Given its scope, it will appeal to scientists, pracademics and professionals from academia, the water industry and involved in policymaking.
    Type of Medium: Online Resource
    Pages: XII, 132 p. 17 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030551377
    Series Statement: PoliMI SpringerBriefs,
    URL: https://doi.org/10.1007/978-3-030-55137-7
    DOI: 10.1007/978-3-030-55137-7
    DDC: 551
    Language: English
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    Rainwater Infiltration in Urban Areas (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Pollution. ; Water. ; Hydrology. ; Physical geography. ; Geology. ; Pollution. ; Water. ; Earth System Sciences.
    Description / Table of Contents: 1. Introduction -- 2. Urban hydrology -- 3. Research of rainwater infiltration -- 4. Percolation facilities -- 5. Legislation – technical standards -- 6. Results of research- Design of percolation facility -- 7. Recommendations.
    Abstract: The book presents a comprehensive study of the percolation of water from surface runoff with a focus on the retention capacity and intensity of precipitation. Discussing the state of the art in scientific knowledge and solutions for the infiltration of water from surface runoff, the book addresses a wide variety of rainwater management issues, from precipitation, surface runoff and water infiltration, to impact on the drainage system. Although modern urban hydrology has improved the management of rainwater runoff for flood protection, public health, and environmental protection, current methods of drainage in urban areas mean that there is a continued threat to the regime of water flow and water resources. In this context, the book presents a new approach to rainwater management based on a unique fusion of hydrology, hydrogeology, urban engineering, and water management. It also includes research findings that are helpful in developing recommendations and technical guidelines for the use of infiltration systems in urban areas.
    Type of Medium: Online Resource
    Pages: XIII, 141 p. 94 illus., 82 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030346980
    Series Statement: Water Science and Technology Library, 89
    URL: https://doi.org/10.1007/978-3-030-34698-0
    DOI: 10.1007/978-3-030-34698-0
    DDC: 551
    Language: English
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    Geological Tour of Devonian and Ordovician Magmatism of Kuznetsk Alatau and Minusinsk Basin : Altay-Sayan Region, Siberia (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Mineralogy. ; Paleontology . ; Geology. ; Mineralogy. ; Paleontology.
    Abstract: This volume provides an overview and tour (with many interesting stops along the way) of Devonian and Ordovician intraplate magmatism and associated sedimentary rocks and tectonics in the regions of Kuznetsk Alatau, Minusinsk Basin and Khakassia in western Siberia. All chapters were written by experts, many of which have been studying these regions for decades. The first book to present and review this information in English for an international audience, it includes both overviews of the magmatic and associated sedimentary history, and selected key field sites, which are described in detail.
    Type of Medium: Online Resource
    Pages: X, 232 p. 140 illus., 124 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030295592
    Series Statement: GeoGuide,
    URL: https://doi.org/10.1007/978-3-030-29559-2
    DOI: 10.1007/978-3-030-29559-2
    DDC: 551
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    Arabian Plate and Surroundings: Geology, Sedimentary Basins and Georesources (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Sedimentology. ; Geophysics. ; Paleontology . ; Geology. ; Sedimentology. ; Geophysics. ; Paleontology.
    Description / Table of Contents: Part I: Sedimentary basins, petroleum resources and reservoirs in the Arabian plate High-resolution stratigraphic architectures, facies anatomies of the Lower Cretaceous Biyadh and Shu’aiba formations, and their implications on platform evolution and global correlation -- The Lower Cretaceous Chouf Sandstone of Lebanon: a regional reservoir level in the Levant? -- Seismic tectono-stratigraphy and hydrocarbon implications of lowstand deep marine Oligo-Miocene siliciclastic reservoirs in the Northern Levant Basin -- Source-to-sink analysis of the Plio-Pleistocene deposits in the Suez rift (Egypt). Part II: Geophysics and structural styles The Southern Atlas front in Tunisia: Regional-scale geometry and structural evolution. U-Pb zircon geochronology and geochemistry of some plutonic rocks from the Afif terrane of Saudi Arabia, Arabian Shield: implications for crustal evolution -- Aeromagnetic data investigation of Al-Shamiyya area, north east of Makkah quadrangle, Saudi Arabia. Part III: Hydrology, hydrogeology and water resources Groundwater contamination of Wadi Haliy area, Southwestern Arabian Shield, Saudi Arabia -- Analysis of rainfall, missing data, frequency and PMP in Al-Madinah area, Western Saudi Arabia -- Hydrochemical assessment of groundwater within the Lower Wadi Ranyah, Western Saudi Arabia using multivariate statistical technique.
    Abstract: This book focuses on the evolution of sedimentary basins of the Arabian Plate and its surroundings. Because these sedimentary basins developed in various tectonic settings, from extensional or transtensional to flexural, transpressional or compressional, their sedimentary sequences provide unique records of the regional geology. Georesources of the Arabian Plate are also described here, including petroleum potential, reservoirs, water resources, fresh water and deep saline aquifers, as well as materials and ore deposits. The book is made by a set of papers authored by geoscientists working in both academia and industry. Numerous chapters describe some regional important geologic features and selected sedimentary basins from the Middle East, North Africa and the Arabian Peninsula domains. Other chapters focus on georesources. A particular focus is given to the geology of Saudi Arabia. This book is an important contribution to the geology of the Arabian Peninsula and its surroundings. In view of the strategic and economic importance of the regional geology and georesources of the Arabian Plate and Surroundings, this volume will constitute an important reference for a wide range of geoscientists interested in the geology of this region, especially those active in petroleum geosciences and related industry. Ultimately, readers will discover important thematic maps in this book.
    Type of Medium: Online Resource
    Pages: VIII, 257 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030218744
    Series Statement: Regional Geology Reviews,
    URL: https://doi.org/10.1007/978-3-030-21874-4
    DOI: 10.1007/978-3-030-21874-4
    DDC: 551
    Language: English
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    Water Resources Systems of the Philippines: Modeling Studies (2020)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Water. ; Hydrology. ; Engineering mathematics. ; Engineering Data processing. ; Computer simulation. ; Geology. ; Water. ; Mathematical and Computational Engineering Applications. ; Computer Modelling.
    Description / Table of Contents: 1.Introduction -- 2.Hydrology, Hydraulics and Water Resources Engineering -- 3.Science and Art of Water Resources Modeling -- 4.Surface and Groundwater Modeling for Water Utilization -- 5.Reservoir Planning and Operations Studies with Optimization-Simulation Models -- 6.Reservoir Sedimentation Studies -- 7.Hydrodynamic and Water Quality Modeling of Bays and Lake -- 8. Pipe Network Distribution Modeling with Optimization -- 9.Climate Change Studies for Reliability of a Reservoir and Groundwater Water Supply -- 10.Environmental Impact Assessment Studies -- 11.Specialized Modeling Studies -- 12.Imperatives and Needs to Improvement of Water Resources Modeling and Applications in the Philippines.
    Abstract: This book presents a number of modeling studies of various water resources systems in the humid tropics and the typical short, steep mountain-to-coast systems in the archipelagic setting of the Philippines. Covering natural and rural systems, urban watersheds and built systems, such as reservoirs and flood control systems, it discusses modeling studies based on pure simulation and combined optimization-simulation. The book offers insights into real-world water resources modeling, and as such is a valuable resource for academics and practitioners in the Philippines, as well as those in other Asian regions with similar water resources systems, and similar issues, problems and concerns.
    Type of Medium: Online Resource
    Pages: XXXIX, 403 p. 233 illus., 210 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030254018
    Series Statement: World Water Resources, 4
    URL: https://doi.org/10.1007/978-3-030-25401-8
    DOI: 10.1007/978-3-030-25401-8
    DDC: 551
    Language: English
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    Lagoa Santa Karst: Brazil's Iconic Karst Region (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Physical geography. ; Conservation biology. ; Ecology . ; Archaeology. ; Paleontology . ; Environmental management. ; Geology. ; Physical Geography. ; Conservation Biology. ; Archaeology. ; Paleontology. ; Environmental Management.
    Description / Table of Contents: Introduction -- 200 years of karst research in the Lagoa Santa area -- Geology of the Lagoa Santa Karst -- The vegetation of the karst region -- Fauna of the Lagoa Santa Karst -- Hydrological behaviour of karst lakes -- Karst soils and their relationship to geomorphology -- Karst landforms -- Karst groundwater routes and dynamics -- Speleogenesis in the Lagoa Santa Karst.
    Abstract: This book discusses the Lagoa Santa Karst, which has been internationally known since the pioneering studies of the Danish naturalist Peter Lund in the early 1800s. It covers the speleogenesis, geology, vegetation, fauna, hydrogeology, geomorphology, and anthropogenic use of the Lagoa Santa Karst and is the first English-language book on this major karst area. The area, which has been at the heart of the debate on the origin and age of human colonization in the Americas, is characterized by a classical and scenic karst landscape with limestone cliffs, karst lakes and karst plains, in addition to numerous solution dolines. More than 1,000 caves have been documented in the area, many with significant archeological and paleontological value. Despite its great importance, the Lagoa Santa Karst faces severe environmental threats due to limestone mining and the expansion of the metropolis of Belo Horizonte and its surrounding towns. The growing recognition of the area’s remarkable significance has led to increasing concern, and a number of protected areas have now been established, improving the conservation status of this landmark karst area.
    Type of Medium: Online Resource
    Pages: X, 330 p. 204 illus., 178 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030359409
    Series Statement: Cave and Karst Systems of the World,
    URL: https://doi.org/10.1007/978-3-030-35940-9
    DOI: 10.1007/978-3-030-35940-9
    DDC: 551
    Language: English
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    Geology of Coal Deposits of South Limburg, The Netherlands : Including Adjacent German and Belgian Areas (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geology.
    Description / Table of Contents: 1. Introduction – History of coal mining in Limburg, and adjacent areas -- 2. The Origin and Classification of Coal – Coalification, macerals, nomenclature of types of coal -- 3. Limburg and adjacent areas in the Carboniferous – Paleogeography, plate tectonics, paleoclimate, position with respect to the equator, the London Brabant Massif and its relation to the coal deposits -- 4. Later burial. Present depth of the coal layers -- 5. Tectonics – uplift and crust extension, the Roergraben, active faults, inactive faults.
    Abstract: This book offers an up-to-date overview of the coal deposits of South Limburg (Netherlands), the Aachen area (Germany), and the Campine area (Belgium). Although the amount of available literature on these coal deposits is quite vast, the majority of the texts date back to the mid-twentieth century, and most publications focus more on the stratigraphy of the coal layers and the rank of the coal. Moreover, the concept of continental drift is largely ignored in these publications. In addition to providing updated information, this book also discusses coal mining in these regions; the formation and petrography of coal; and the geological evolution of Western Europe/the Netherlands, Germany and Belgium. In order to explain the tropical nature of the flora in the Carboniferous period, paleogeographic aspects are also taken into account. .
    Type of Medium: Online Resource
    Pages: XII, 78 p. 49 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030182861
    Series Statement: SpringerBriefs in Earth Sciences,
    URL: https://doi.org/10.1007/978-3-030-18286-1
    DOI: 10.1007/978-3-030-18286-1
    DDC: 551
    Language: English
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    The Precambrian Geology of Lithuania : An Integratory Study of the Platform Basement Structure and Evolution (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Mineralogy. ; Geochemistry. ; Geodynamics. ; Geology. ; Mineralogy. ; Geochemistry. ; Geodynamics.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Research History and The Sources Of Information -- Chapter 3. The Structural Subdivision of The Crust -- Chapter 4. Supracrustal Rocks of The Lithuanian-Belarus Belt -- Chapter 5. Felsic Metavolcanic Rocks of The Sūduva Suite.
    Abstract: This book shows the results of structural, compositional and evolutionary investigations of the Precambrian crust of the East European Craton in Lithuania and adjacent areas. This work contributes to the recognition of the platform basement, which remains weekly investigated worldwide, despite it encompassing the surfaces of cratons. It presents a methodological example of systematic studies of the covered platform basement, integrating petrological, geochemical, isotopic, and geophysical methods, as well as geological mapping, in order to present comprehensive geological picture of the subject matter. In a systematic and summarized form, factual data and intellectual material acquired by researchers are combined. Important papers and industrial reports (also written in Russian and Lithuanian) make this information accessible for both local and international scientists and practitioners and stimulate the advertising, application, and augmentation of this knowledge.
    Type of Medium: Online Resource
    Pages: XVI, 203 p. 215 illus., 202 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030968557
    Series Statement: Regional Geology Reviews,
    URL: https://doi.org/10.1007/978-3-030-96855-7
    DOI: 10.1007/978-3-030-96855-7
    DDC: 551
    Language: English
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    Spectral Methods for the Estimation of the Effective Elastic Thickness of the Lithosphere (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geotechnical engineering. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Isostasy, Flexure and Strength -- The Fourier Transform -- Multitaper Spectral Estimation -- The Continuous Wavelet Transform -- Admittance, Coherency and Coherence -- Map Projections -- Loading and Flexure of an Elastic Plate -- Gravity and Admittance of a Flexed Plate -- The Load Deconvolution Method -- Synthetic Testing -- Practical Te Estimation.
    Abstract: Although several excellent works exist that describe the effective elastic thickness (Te) of the lithosphere—its theory, significance and relevance to Earth sciences in general—none cover the details of the methods for its estimation. This book brings together the disparate knowledge required to estimate Te in one handy volume: signal processing, harmonic analysis, civil engineering, and foundational mathematics and physics, in addition to the relevant geophysics and, to a lesser extent, geology. Its two principal focus areas are spectral estimation, covering various approaches to estimating the admittance and coherence between gravity and topography using Slepian multitapers and fan wavelets; and algebraic and finite difference solutions of the plate bending partial differential equation in a variety of geological settings. This book would be suitable for postgraduate students beginning their research, up to faculty professors interested in diversifying their skills.
    Type of Medium: Online Resource
    Pages: XXII, 457 p. 191 illus., 185 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031108617
    Series Statement: Advances in Geophysical and Environmental Mechanics and Mathematics,
    URL: https://doi.org/10.1007/978-3-031-10861-7
    DOI: 10.1007/978-3-031-10861-7
    DDC: 551
    Language: English
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    Plate Tectonics : Continental Drift and Mountain Building (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geodynamics. ; Geomorphology. ; Geology. ; Geodynamics. ; Geomorphology.
    Description / Table of Contents: 1. Contractional theory, continental drift and plate tectonics -- 2 Plate movements and their geometric relationships -- 3. Continental graben structures -- 4. Passive continental margins and abyssal plains -- 5. Mid-ocean ridges -- 6. Hot spots -- 7. Subduction zones, island arcs and active continental margins -- 8. Transform faults -- 9. Terranes -- 10. Early Precambrian plate tectonics -- 11. Plate tectonics and mountain building -- 12. Old orogens -- 13. Young orogens - the Earth's loftiest places.
    Abstract: This textbook explains how mountains are formed and why there are old and young mountains. It provides a reconstruction of the Earths paleogeography and shows why the shapes of South America and Africa fit so well together. Furthermore, it explains why the Pacific is surrounded by a ring of volcanos and earthquake-prone areas while the edges of the Atlantic are relatively peaceful. This thoroughly revised textbook edition addresses all these questions and more through the presentation and explanation of the geodynamic processes upon which the theory of continental drift is based and which have led to the concept of plate tectonics. It is a source of information for students of geology, geophysics, geography, geosciences in general, general natural sciences, as well as professionals, and interested layman.
    Type of Medium: Online Resource
    Pages: X, 245 p. 195 illus., 194 illus. in color. , online resource.
    Edition: 2nd ed. 2022.
    ISBN: 9783030889999
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-030-88999-9
    DOI: 10.1007/978-3-030-88999-9
    DDC: 551
    Language: English
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    Anthropogenic Aquifer Recharge : WSP Methods in Water Resources Evaluation Series No. 5 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Pollution. ; Sustainability. ; Environment. ; Geology. ; Pollution. ; Sustainability. ; Environmental Sciences.
    Description / Table of Contents: Introduction to Anthropogenic Aquifer Recharge -- Hydrogeology Basics – Aquifer Types and Hydraulics -- Vadose Zone Hydrology Basics -- Groundwater Recharge and Aquifer Water Budgets -- Geochemistry and Managed Aquifer Recharge Basics -- Anthropogenic Aquifer Recharge and Water Quality -- Contaminant Attenuation and Natural Aquifer Treatment -- MAR Project Implementation -- MAR Hydrogeological and Hydrochemistry Evaluation Techniques -- Vadose Zone Testing Techniques Clogging -- Pretreatment.-ASR and Aquifer Recharge Using Wells -- Groundwater Banking -- Surface-Spreading Systems – Infiltration Basins -- Surface-Spreading Systems (Non-Basin) -- Vadose Zone Infiltration Systems -- Recharge and Recovery Treatment Systems -- Soil-Aquifer Treatment -- Riverbank Filtration -- Saline-Water Intrusion Management -- Wastewater MAR and Indirect Potable Reuse -- Low Impact Development and Rainwater Harvesting -- Unmanaged and Unintentional Recharge.
    Abstract: The book is an overview of the diversity of anthropogenic aquifer recharge (AAR) techniques that use aquifers to store and treat water. It focusses on the processes and the hydrogeological and geochemical factors that affect their performance. This book is written from an applied perspective with a focus of taking advantage of global historical experiences, both positive and negative, as a guide to future implementation. Most AAR techniques are now mature technologies in that they have been employed for some time, their scientific background is well understood, and their initial operational challenges and associated solutions have been identified. However, opportunities exist for improved implementation and some recently employed and potential future innovations are presented. AAR which includes managed aquifer recharge (MAR) is a very important area of water resources management and there is no recent books that specifically and comprehensively addresses the subject. .
    Type of Medium: Online Resource
    Pages: XXV, 861 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030110840
    Series Statement: Springer Hydrogeology,
    URL: https://doi.org/10.1007/978-3-030-11084-0
    DOI: 10.1007/978-3-030-11084-0
    DDC: 551
    Language: English
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  • 92
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    Oil and Gas Reservoir Prospecting and Exploration : High-Resolution Seismic (HRS) techniques and technology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Engineering geology. ; Geotechnical engineering. ; Geology. ; Geoengineering. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Chapter 1-Introduction -- Chapter 2-Seismic modeling of wave field dynamic parameters -- Chapter 3-Methods for solving inverse dynamic seismic problems -- Chapter 4-Processing and automated interpretation of well logging data -- Chapter 5-Elastic wave velocity and gradient fields for heterogeneous geological media -- Chapter 6-Determination of statistical dependencies between geological and geophysical characteristics of the real subsurface environment -- Chapter 7-Detailed interpretation of high-resolution seismic data in various seismic and geological conditions -- Chapter 8-Examples of HRS-Geo technology used in other regions -- Chapter 9-Conclusion. .
    Abstract: This book discusses topical issues of detailed seismic data interpretation using high-resolution seismic (HRS) techniques, which are based on the numerical method developed by the authors for solving the inverse dynamic seismic problem (IDSP). The authors highlight the range of issues related to the development and application of HRS-Geo technologies on a variety of seismic data, and analyze a significant amount of practical material in various seismic and geological conditions. This analysis allows for the accurate estimation of geological indicators in sediments that are most important for the prediction and exploration of oil and gas deposits, including lithological composition, reservoir properties, and the nature and degree of reservoir rock saturation with fluids. The book is intended for professionals involved in seismic data processing and geological interpretation, students of geophysical and geological specialties, graduate students of these specializations.
    Type of Medium: Online Resource
    Pages: XXIII, 419 p. 200 illus., 167 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030843892
    URL: https://doi.org/10.1007/978-3-030-84389-2
    DOI: 10.1007/978-3-030-84389-2
    DDC: 551
    Language: English
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  • 93
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    Online Resource
    Progress in Landslide Research and Technology, Volume 1 Issue 1, 2022 (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Geomorphology. ; Geotechnical engineering. ; Natural Hazards. ; Geomorphology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Chapter 1. Aim and Outline of the Book Series “Progress in Landslide Research and Technology (Kyoji Sassa) -- Part I. International Consortium on Landslides and International Programme on Landslides -- Chapter 2. International Consortium on Landslides: from IDNDR, IGCP, UNITWIN, WCDRR 2 & 3 to Kyoto Landslide Commitment 2020 (Kyoji Sassa) -- Chapter 3. International Programme on Landslides – A Short Overview of its Historical Development (Matjaž Mikoš) -- Part II. Original Articles -- Chapter 4. Understanding and Reducing the Disaster Risk of Landslide-induced Tsunamis: Outcome of the Panel Discussion and the World Tsunami Awareness Day Special Event of the Fifth World Landslide Forum (Shinji Sassa) -- Chapter 5. Natural-hazard-related web observatory as a sustainable development tool (Matjaž Mikoš) -- Chapter 6. Mapping post-fire monthly erosion rates at the catchment scale using empirical models implemented in GIS. A case study in Northern Italy (Damiano Vacha) -- Chapter 7. Mechanisms of shallow rainfall-induced landslides from Australia: insights into field and laboratory investigations (Ivan Gratchev) -- Chapter 8. Design protection barriers against flow-like landslides (Sabatino Cuomo) -- Chapter 9. Landslide warning systems in low- and lower-middle-income countries: future challenges and societal impact (Irasema Alcántara-Ayala) -- Chapter 10. The role of translational landslides in the evolution of cuesta topography (Shinro Abe).
    Abstract: This open access book is the first issue of the first volume of the ICL new book series “Progress in Landslide Research and Technology,” founded by the Launching Declaration of the ICL Open Access Book Series “Progress in Landslide Research and Technology (P-LRT)” for the Kyoto Landslide Commitment 2020 on 3 November 2021 during the Fifth World Landslide Forum (WLF5) in Kyoto, Japan. This book contains the followings: Forewords for the book series and Opening Greetings of WLF5 International Consortium on Landslides and International Programme on Landslides Original articles Review articles IPL Projects, World Centres of Excellence on Landslide Risk Reduction, and Kyoto Landslide Commitment 2020 ICL Landslide Teaching Tools Technical notes and Case studies Official Promoters of the Kyoto Landslide Commitment 2020 (public and private) List of ICL members Prof. Kyoji Sassa is the founding President and the Secretary General of the ICL and the Secretary General of the Kyoto Landslide Commitment 2020. He is the Editor-in-Chief of the International Journal Landslides and ICL book series P-LRT. Prof. Kazuo Konagai is Professor Emeritus of the University of Tokyo and Principal Researcher at the ICL headquarters. He is an Assistant Editor-in-Chief of the ICL book series P-LRT. Prof. Binod Tiwari is the Vice President of the ICL for America. He is a professor of civil and environmental engineering and the Associate Vice President for Research and Sponsored Projects at the California State University, Fullerton, California, USA. He is an Assistant Editor-in-Chief of the ICL book series P-LRT. Prof. Zeljko Arbanas is the Vice President of the ICL for Europe. He is a professor at the Faculty of Civil Engineering, University of Rijeka, Croatia. He is an Assistant Editor-in-Chief of the International Journal Landslides and ICL book series P-LRT. Dr. Shinji Sassa is Head of Soil Dynamics Group and Research Director of International Research Center for Coastal Disasters, Port and Airport Research Institute, National Institute of Maritime, Port and Aviation Technology, Japan. He is an Editor of the International Journal Landslides and ICL book series P-LRT.
    Type of Medium: Online Resource
    Pages: XXX, 474 p. 470 illus., 439 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031168987
    Series Statement: Progress in Landslide Research and Technology,
    URL: https://doi.org/10.1007/978-3-031-16898-7
    DOI: 10.1007/978-3-031-16898-7
    DDC: 551
    Language: English
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  • 94
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    Online Resource
    Geomechanics of Oil and Gas Wells (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geophysics. ; Environment. ; Geology. ; Geophysics. ; Environmental Sciences.
    Description / Table of Contents: Stress-Strain State of Rocks -- Deformation and Fracture of Rocks In The Presence of Filtration -- Mechanical and Mathematical, and Experimental Modeling of Oil and Gas Well Stability -- Equipment For Studying Deformation and Strength Properties of Rocks In Triaxial Loading -- Loading Programs For Rock Specimens On Triaxial Independent Loading Test System (Tilts) -- Dependence of Permeability On Stress State -- Influence of Filtration On Stress-Strain State and Rock Fracture In The Well Vicinity -- Results of Tests of Rock Specimens By Using Tilts -- Mathematical Modeling of Mechanical and Filtration Processes In Near-Wellbore Zone -- Directional Unloading Method - A New Approach To Enhancing of Oil and Gas Well Productivity.
    Abstract: The book presents an integrated approach to studying the geomechanical processes occurring in oil and gas-bearing formations during their development. It discusses the choice of a model that takes into account the basic properties of rocks; experiments to find model parameters; numerical modeling; and direct physical modeling of deformation and filtration processes in reservoir and host rocks. Taking into account features of rock behavior, such as anisotropy of the mechanical properties of rocks during elastoplastic deformation; dependence of permeability on the total stress tensor; the contribution of the filtration flow to the formation stress state; and the influence of tangential as well as normal stresses on the transition to inelastic deformation, it demonstrates how the presented approach allows the practical problems of increasing the productivity of wells, oil recovery, and ensuring the stability of wellbores to be solved. The book is intended for specialists, including geoengineers working in the oil and gas sector, teachers, graduate students and students, as well as all those interested in scientific and technological developments to meet the enormous demand for raw materials and energy. .
    Type of Medium: Online Resource
    Pages: XVI, 166 p. 140 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030266080
    Series Statement: Advances in Oil and Gas Exploration & Production,
    URL: https://doi.org/10.1007/978-3-030-26608-0
    DOI: 10.1007/978-3-030-26608-0
    DDC: 551
    Language: English
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  • 95
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    Online Resource
    Natural Resource Management in the Thar Desert Region of Rajasthan (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Human ecology Study and teaching. ; Environment. ; Environmental management. ; Geology. ; Environmental Studies. ; Environmental Sciences. ; Environmental Management.
    Description / Table of Contents: An Overview of World Deserts with Special Reference to Thar Desert -- People and Culture of the Thar Desert -- Shift in Land Use Pattern of Thar Desert -- Land and Water Resource Management in the Thar Desert Region -- Crop Production Practices in the Thar Desert Region of Rajasthan -- Livestock and its Management Practices in Thar Desert, Rajasthan -- Arid Agroforestry for Thar Desert -- Soil Conservation and Water Harvesting for Sustainable Agriculture in Arid Regions -- Community Land Management in the Thar Desert -- Women Empowerment in Thar Desert Region -- Livelihood Opportunities in the Thar Region -- Potential Agri-Business in the Thar Desert -- Multidimensional Development in Thar Desert Region of Rajasthan -- Sustainable Natural Resource Management in Thar Desert-Way Ahead. .
    Abstract: This book covers a wide range of issues related to the Thar Desert Region of Rajasthan from an integrated and sustainable development perspective. The chapters in this book cover regional and local issues which are discussed with reference to the past scenario, the present practices, and the future strategies. Some of the issues addressed in this book like arid agroforestry, livelihood, and multidimensional development give it a cutting edge over other related publications currently available in the market. The chapters are supported with relevant pictures which will help the reader to connect with the issues being discussed. This book is useful to students, civil services aspirants, researchers, environmentalists, geographers, and non-professionals who are interested in deserts and desert development.
    Type of Medium: Online Resource
    Pages: XXII, 342 p. 52 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031345562
    URL: https://doi.org/10.1007/978-3-031-34556-2
    DOI: 10.1007/978-3-031-34556-2
    DDC: 551
    Language: English
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  • 96
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    Understanding and Reducing Landslide Disaster Risk : Volume 1 Sendai Landslide Partnerships and Kyoto Landslide Commitment (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Environmental management. ; Environmental policy. ; Natural Hazards. ; Environmental Management. ; Environmental Policy.
    Description / Table of Contents: Forum Lectures and Special Lecture: On the prediction of landslides and their consequences -- Design recommendations for single and dual rigid debris flow barriers with and without basal clearance -- The rockfall failure hazard assessment: summary and new advances -- Progress and lessons learned from responses to landslide disasters -- Behind-the-scenes in mitigation of landslides and other geohazards in low income countries - in memory of Hiroshi Fukuoka -- The impact of climate change on landslide hazard and risk -- Sendai Landslide Partnerships, Kyoto Landslide Commitment, and International programme on Landslides: Kyoto 2020 Commitment for Global Promotion of Understanding and Reducing Landslide Disaster Risk -- International Consortium on Landslides -- The ICL journal Landslides - 16 years of capacity development for landslide risk reduction -- UNESCO/KU/ICL UNITWIN Cooperation Programme-Members and recent activities -- International Programme on Landslides (IPL) -- SATREPS project for Sri Lanka with regard to “Development of early warning technology of Rain-induced Rapid and Long-travelling Landslides” -- Central Asia – rockslides' and rock avalanches' treasury and workbook -- Results of recent monitoring activities on landslide Umka, Belgrade, Serbia - IPL 181 -- Landslides in Weathered Flysch: From Activation to Deposition (WCoE 2017-2020) -- Report of the Croatian WCoE 2017-2020: From landslide mapping to risk assessment -- LARAM School: an ongoing experience -- Advanced technologies for Landslides (WCoE 2017-2020) -- Extreme rainfall event and its aftermath analysis - IPL 210 project progress report -- Complex geomorphological and engineering geological research of landslides with adverse societal impacts -- Report of the IPL-219, IPL-220 and Croatian WCoE 2017-2020: From landslide investigation to landslide prediction and stabilization -- Landslide-induced Tsunamis: Simulation of Tsunami waves induced by coastal and submarine landslides in Japan -- On the use of statistical analysis to understand submarine landslide processes and assess their hazard -- The continuing underestimated tsunami hazard from submarine landslides -- December 11, 2018 landslide and 90-m icy tsunami in the Bureya water reservoir -- The link between upper-slope submarine landslides and mass transport deposits in the hadal trenchs -- Tsunami from the San Andrés Landslide on El Hierro, Canary Islands: first attempt using simple scenario -- A sedimentological study of turbidite layers on a deep–sea terrace in the Japan Trench -- Flank failure of the volcanic Turtle Island and the submarine landslide in the southernmost Okinawa Trough -- Numerical simulation for tsunami generation due to a landslide -- Dealing with mass flow-induced tsunamis at Stromboli volcano: monitoring strategies through multi-platform remote sensing -- Detailed seafloor observation on a deep-sea terrace along the Japan Trench after the 2011 Tohoku Earthquake -- Landslides at UNESCO designates sites and contribution from WMO, FAO, IRDR -- Landslides at UNESCO-designated sites -- Traditional knowledge and local expertise in landslide risk mitigation of world heritages sites -- Reconstruction of the slope instability conditions before the 2016 failure in an urbanized district of Florence (Italy), a UNESCO World Heritage Site -- Integrating Kinematic analysis and Infrared Thermography for instability processes assessment in the rupestrian monastery complex of David Gareja (Georgia) -- Shallow landslide susceptibility assessment in the High City of Antananarivo (Madagascar) -- Thermo-mechanical cliff stability at tomb KV42 in the Valley of the Kings, Egypt -- Collaboration in MHEWS through an Integrated Way: The Great Efforts Contributed by Multi-stakeholder Partnership at National, Regional and International Levels -- Resilient Watershed Management: Landscape Approach to Climate Change and Disaster Risk Reduction -- Integrating DRR into the conservation and management mechanisms of the internationally designated sites – view of IRDR -- Landslide hazard and risk assessment for civil protection early response -- Size matters: the impact of small, medium and large landslide disasters -- Practices of Public Participation Early Warning System for Geological Hazards in China -- Education and Capacity Development for Risk Management and Risk Governance -- Early warning systems in Italy: state-of-the-art and future trends -- Community-based landslide risk management in contrasting social environments, cases from the Czech Republic -- Refinement Progresses on Freeway Slope Maintenance after a Huge Landslide Disaster -- Landslide exposure community-based mapping: a first encounter in a small rural locality of Mexico -- Co-producing data and decision support tools to reduce landslide risk in the humid tropics -- ICT-based landslide disaster simulation drill: Road to achieve 2030 global commitment -- A Preliminary Work of Safety Potential Analysis Model for Anchors Used on Freeway Slopes -- Initial Experiences of Community Involvement in an Early Warning System in Informal Settlements in Medellín, Colombia -- Capacity Building and Community Preparedness towards Landslide Disaster in Pagerharjo Village, Kulon Progo Regency of Yogyakarta, Indonesia -- Protection of a cultural heritage site in Croatia from rockfall occurrences -- Cutting-edge technologies aiming for better outcomes of landslide disaster mitigation.
    Abstract: This book is a part of ICL new book series “ICL Contribution to Landslide Disaster Risk Reduction” founded in 2019. Peer-reviewed papers submitted to the Fifth World Landslide Forum were published in six volumes of this book series. This book contains the followings: • Four Forum lectures and one award paper • Sendai Landslide Partnerships, Kyoto Landslide Commitment, and International Programme on Landslides. • Landslide-induced tsunamis • Landslides at UNESCO designates sites and contribution from WMO, FAO, and IRDR • Education and Capacity Development for Risk Management and Risk Governance Prof. Kyoji Sassa is the Founding President and the Secretary-General of International Consortium on Landslides (ICL). He has been the Editor-in-Chief of International Journal Landslides since its foundation in 2004. Prof. Matjaž Mikoš is the Vice President of International Consortium on Landslides and Vice President of Slovenian Academy of Engineering. He is a Professor and Dean of Faculty of Civil and Geodetic Engineering, University of Ljubljana, Slovenia. Dr. Shinji Sassa is Head of Soil Dynamics Group and Research Director of International Research Center for Coastal Disasters, Port and Airport Research Institute, National Institute of Maritime, Port and Aviation Technology, Japan. Prof. Peter Bobrowsky is the President of International Consortium on Landslides. He is a Senior Scientist of Geological Survey of Canada, Ottawa, Canada. Prof. Kaoru Takara is the Executive Director of International Consortium on Landslides. He is a Professor and Dean of Graduate School of Advanced Integrated Studies (GSAIS) in Human Survivability (Shishu-Kan), Kyoto University. Dr. Khang Dang is the Secretary General of the Fifth World Landslide Forum. He also serves as the Research Promotion Officer of ICL and a Lecturer at the University of Science, Vietnam National University, Hanoi.
    Type of Medium: Online Resource
    Pages: XXV, 641 p. 527 illus., 483 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030601966
    Series Statement: ICL Contribution to Landslide Disaster Risk Reduction,
    URL: https://doi.org/10.1007/978-3-030-60196-6
    DOI: 10.1007/978-3-030-60196-6
    DDC: 551
    Language: English
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  • 97
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    Online Resource
    Ice Age Floodscapes of the Pacific Northwest : A Photographic Exploration (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geomorphology. ; Geographic information systems. ; Physical geography. ; Mineralogy. ; Geology. ; Geomorphology. ; Geographical Information System. ; Earth System Sciences. ; Mineralogy.
    Description / Table of Contents: Chapter 1.Introduction -- Chapter 2-Background -- Chapter 3-Ice age outbursts -- Chapter 4-Channeled scabland -- Chapter 5-Erosional features -- Chapter 6-Depositional features. .
    Abstract: This heavily illustrated book contains descriptions and geologic interpretations of photographs (mostly aerial) illustrating the power and magnitude of repeated Ice Age flooding in the Pacific Northwest, as recently as 14,000 years ago. The scale of Ice Age floods was so huge that today it is often difficult to see and appreciate the power and magnitude of such megafloods from ground level. However, from the air, landforms created by the floods often come into clear focus. Aerial images, obtained via unmanned aerial vehicle (drone) as well as fixed-wing airplane, add a new perspective on evidence gathered by dozens of scientists since 1923.
    Type of Medium: Online Resource
    Pages: XI, 180 p. 298 illus., 291 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030530433
    URL: https://doi.org/10.1007/978-3-030-53043-3
    DOI: 10.1007/978-3-030-53043-3
    DDC: 551
    Language: English
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  • 98
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    Online Resource
    Frequency Analyses of Natural Extreme Events : A Spreadsheets Approach (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Geology. ; Geotechnical engineering. ; Natural Hazards. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Introduction -- Basic Notions of Probability and Statistics for Flood -- Normal Distribution -- Log-Normal Distribution with 2 parameters -- Log-Normal Distribution with 3 parameters -- Gamma Distribution -- Pearson Type III Distribution -- Log-Pearson Type III Distribution -- Extreme Value type I Distribution -- General Extreme Value Distribution -- Log-Normal Distribution with 3 parameters for the Minima -- Pearson Type III Distribution for the Minima -- Extreme Value Type III Distribution for the Minima -- General Extreme Value Distribution for the Minima. .
    Abstract: This book is of paramount importance in the fields of engineering and applied sciences, given that through the values obtained by these procedures, many structures, like spillways of dams and highway culverts, are designed and constructed. The main aim of this book is to provide procedures for implementing many probability distribution functions, all of them based on using a standard and a common computational application known as Excel, which is available to any personal computer user. The computer procedures are given in enough detail, so readers can develop their own Excel worksheets. All the probability distribution functions in the book have schemes to estimate its parameters, quantiles, and confidence limits through the methods of moments and maximum likelihood.
    Type of Medium: Online Resource
    Pages: XVII, 410 p. 304 illus., 300 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030863906
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-030-86390-6
    DOI: 10.1007/978-3-030-86390-6
    DDC: 551
    Language: English
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  • 99
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    Online Resource
    Geology of North Africa and the Mediterranean: Sedimentary Basins and Georesources (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Sedimentology. ; Mining engineering. ; Geotechnical engineering. ; Power resources. ; Geology. ; Sedimentology. ; Mining and Exploration. ; Geotechnical Engineering and Applied Earth Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Chapter 1. The Mediterranean Sea: a laboratory to characterize micro-continental drift and oceanic basin formation processes -- Chapter 2. The westernmost Tethyan margins in the Rif Belt (Morocco), a review -- Chapter 3. The Tellian units, the Sellaoua window and the High Medjerda foreland in the Souk Ahras area, NE Algeria -- Chapter 4. Facies Analyses and Basin Evolution of the Cretaceous-Tertiary Rift-related Sedimentary Succession of Haddat Ash Sham area, West Central Arabian Shield, Saudi Arabia -- Chapter 5. Petroleum system evaluation of Upper Cretaceous and Eocene plays, offshore and onshore southern Pelagian Basin, Tunisia.
    Abstract: This book summarizes the links between the evolution of sedimentary basins of Northern Africa and Peri-Mediterranean in different tectonic settings and the distribution of georesources in those basins. Georesources include fossil energy, geothermal energy, deep aquifers, minerals and deposits. This book also provides key information for energy resources in these important areas. The book is in part a compilation of selected papers from Atlas Georesources International Congress, Hammamet, Tunisia, (AGIC 2017) which were extended after the congress in addition to other contributions from geoscientists based at some universities and companies from the region. It is organized in a set of research studies focusing on the architecture, geodynamic evolution and modeling of sedimentary basins in the Middle East, North Africa and the Mediterranean domain. Future developments in the exploration for water, energy and other georesources are very important in these regions. In this context, this book constitutes an important reference for a wide range of geoscientists and companies as it defines the distribution and potentialities of these resources. .
    Type of Medium: Online Resource
    Pages: XVIII, 284 p. 233 illus., 224 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031187476
    Series Statement: Regional Geology Reviews,
    URL: https://doi.org/10.1007/978-3-031-18747-6
    DOI: 10.1007/978-3-031-18747-6
    DDC: 551
    Language: English
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  • 100
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    Online Resource
    Medical Geology in Mining : Health Hazards Due to Metal Toxicity (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Environmental health. ; Mining engineering. ; Geotechnical engineering. ; Toxicology. ; Geology. ; Environmental Health. ; Mining and Exploration. ; Geotechnical Engineering and Applied Earth Sciences. ; Medical Toxicology.
    Description / Table of Contents: Health Hazards Due to Metal Toxicity -- Detection and Remediation of Silicosis -- Coal Worker’s Pneumoconiosis -- Tuberculosis in Mine Workers -- Metal Toxicity Due to Mining -- Fluorosis.
    Abstract: This book discusses a wide range of health-related mining issues, with particular reference to occupational diseases, metal toxicity, postural injuries in miners, modern fire safety controls, noise-induced hearing loss prevention, and noise mapping. Mining plays a central role in the development of modern civilization. By providing the essential raw materials, mining ensures progress, safety, and comfort of people. However, this necessary activity comes with several woes, the most important of which are occupational health hazards. Mines act as sources of constant danger and risk to the miners irrespective of the scale of mining, such as large-scale industrial mining or small-scale artisanal mining. Not only are there accidents, but continuous exposure to dust, metal toxicity, hazardous gases and fumes, and loud noises, giving rise to a variety of diseases to mine workers. The comprehensive coverage of issues and the case studies will make this book an essential reference and critical reading. Medical geology is a necessary discipline in earth sciences. Unfortunately, not much literature is available on this subject. Therefore, this book is essential for practicing engineers and supervisors in mines, health and safety professionals, researchers, and mining industry students.
    Type of Medium: Online Resource
    Pages: XV, 359 p. 81 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030994952
    Series Statement: Springer Geology,
    URL: https://doi.org/10.1007/978-3-030-99495-2
    DOI: 10.1007/978-3-030-99495-2
    DDC: 551
    Language: English
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