Publication Date:
1984-01-27
Description:
The genetic relationships among molecularly cloned prototype viruses representing all of the major oncovirus genera were investigated by molecular hybridization and nucleotide sequence analysis. One of the major progenitors of the pol genes of such viruses gives rise to mammalian type C viruses and another gives rise to type A, B, D, and avian type C oncoviruses. Evidence of unusual patterns of homology among the env genes of mammalian type C and D oncoviruses illustrates that genetic interactions between their progenitors contributed to the evolution of oncoviruses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chiu, I M -- Callahan, R -- Tronick, S R -- Schlom, J -- Aaronson, S A -- New York, N.Y. -- Science. 1984 Jan 27;223(4634):364-70.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6197754" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
Avian Sarcoma Viruses/genetics
;
Base Sequence
;
*Biological Evolution
;
Cloning, Molecular
;
DNA Restriction Enzymes
;
*Genes, Viral
;
Nucleic Acid Heteroduplexes
;
Nucleic Acid Hybridization
;
RNA-Directed DNA Polymerase/*genetics/metabolism
;
Recombination, Genetic
;
Retroviridae/classification/*genetics
;
Viral Envelope Proteins/genetics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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