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  • Articles  (8)
  • Latest Papers from Table of Contents or Articles in Press  (8)
  • Life Sciences
  • Physics
  • Species Specificity
  • American Association for the Advancement of Science (AAAS)  (8)
  • 1980-1984  (8)
  • 1975-1979
  • 1925-1929
  • 1983  (8)
Collection
  • Articles  (8)
Source
  • Latest Papers from Table of Contents or Articles in Press  (8)
Keywords
Publisher
  • American Association for the Advancement of Science (AAAS)  (8)
Years
  • 1980-1984  (8)
  • 1975-1979
  • 1925-1929
Year
Journal
Topic
  • 1
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    Protons and anaerobiosis (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-03-25
    Description: During oxygen limitation in animals, glucose can be fermented via several metabolic pathways varying in energetic efficiency and leading to various end products (such as lactate, alanopine, octopine, succinate, or propionate). Because of opposite pH dependencies of proton production by fermentation and by hydrolysis of adenosine triphosphate formed in the fermentation, the total number of moles of protons generated is always two per mole of the fermentable substrate. However, two and three times more adenosine triphosphate can be turned over per mole of protons produced in succinate and propionate fermentations, respectively, than in lactate fermentation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hochachka, P W -- Mommsen, T P -- New York, N.Y. -- Science. 1983 Mar 25;219(4591):1391-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6298937" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphate/metabolism ; Aerobiosis ; Anaerobiosis ; Animals ; Fermentation ; Glucose/*metabolism ; *Glycolysis ; Lactates/metabolism ; Mollusca/metabolism ; *Protons ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Z-DNA moves toward "real biology" (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-11-04
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kolata, G -- New York, N.Y. -- Science. 1983 Nov 4;222(4623):495-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6623088" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Dna ; Eukaryota/genetics ; Humans ; *Nucleic Acid Conformation ; Species Specificity ; Structure-Activity Relationship
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Paedomorphosis and neoteny in the pygmy chimpanzee (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-11-04
    Description: The strongly paedomorphic skull form in the pygmy chimpanzee results from the heterochronic process of neoteny. This cranial paedomorphosis and neoteny in Pan paniscus may be related to reduced sexual dimorphism in morphology and behavior. The interspecific differences in form result from shifts in the rate and timing of similar patterns of development.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Shea, B T -- New York, N.Y. -- Science. 1983 Nov 4;222(4623):521-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6623093" target="_blank"〉PubMed〈/a〉
    Keywords: Aging ; Animals ; Biological Evolution ; Biometry ; Bone Development ; Bone and Bones/anatomy & histology ; Pan troglodytes/*anatomy & histology ; Skull/*anatomy & histology/growth & development ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Human macrophages armed with murine immunoglobulin G2a antibodies to tumors destroy human cancer cells (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-08-26
    Description: Macrophages isolated from tumor-bearing patients as well as cultured human monocytes express Fc receptors that cross-react strongly with murine immunoglobulins of the G2a but only slightly or not at all with the G1, G2b, or G3 subclasses. Such macrophages in the presence of murine immunoglobulin G2a monoclonal antibodies to tumors mediated the killing of tumor cells in vitro. These data suggest that monoclonal antibodies of the G2a subclass may be useful in the immunotherapy of human cancer.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Steplewski, Z -- Lubeck, M D -- Koprowski, H -- CA-10815/CA/NCI NIH HHS/ -- CA-21124/CA/NCI NIH HHS/ -- CA-25874/CA/NCI NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1983 Aug 26;221(4613):865-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6879183" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibodies, Monoclonal/*immunology ; Cells, Cultured ; Cytotoxicity, Immunologic ; Humans ; *Immunity, Cellular ; Immunoglobulin G/immunology ; Immunotherapy ; Macrophages/*immunology ; Mice ; Monocytes/immunology ; Neoplasms, Experimental/immunology/therapy ; Receptors, Fc/*immunology ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    BK viral enhancer element and a human cellular homolog (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-11-18
    Description: Comparison of two closely related primate papovaviruses, simian virus 40 (SV40) and human BK virus (BKV), reveals that the only region of extensive divergence, the tandem sequences adjacent to the origins of DNA replication, is responsible in SV40 for enhancing early gene expression. This study demonstrates a similar enhancer function for the analogous repeated region in BKV. The dissimilarity in sequence of the BKV and SV40 enhancer elements suggests that they may have been acquired since SV40 and BKV diverged. A locus cloned from the human genome homologous to the BKV tandem repeats has been shown to function as low level enhancer element in mammalian cells. These data support the hypothesis that viral enhancer sequences may be evolutionarily related to host cell sequences.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rosenthal, N -- Kress, M -- Gruss, P -- Khoury, G -- New York, N.Y. -- Science. 1983 Nov 18;222(4625):749-55.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6314501" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; BK Virus/*genetics ; Base Sequence ; Biological Evolution ; DNA, Viral/*genetics ; Gene Expression Regulation ; *Genes, Regulator ; Humans ; Plasmids ; Polyomavirus/*genetics ; Repetitive Sequences, Nucleic Acid ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Strain differences in rat brain epinephrine synthesis: regulation of alpha-adrenergic receptor number by epinephrine (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-23
    Description: Inbred tht strains Fischer 344 (F344) and Buffalo (BUF) differ in serveral physiological and behavioral measures. It was found that the activity of adrenomedullary and regional brain phenylethanolamine N-methyltransferase is at least four times higher in F344 rats than in BUF rats; these strain-dependent differences corresponded directly with the epinephrine content of the medulla-pons and hypothalamus. Conversely, alpha-adrenergic receptor density in brain regions containing phenylethanolamine N-methyltransferase is two to three times lower in F344 rats than in BUF rats; alpha-receptors in frontal cortex (a brain region lacking phenylethanolamine N-methyltransferase activity and epinephrine) are similar in both strains. These findings suggest that strain-dependent differences in alpha-receptors are regulated by inherited differences in presynaptic adrenergic neuronal function in different brain regions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Perry, B D -- Stolk, J M -- Vantini, G -- Guchhait, R B -- U'Prichard, D C -- DA 02763/DA/NIDA NIH HHS/ -- MH 32842/MH/NIMH NIH HHS/ -- NS 15595/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1983 Sep 23;221(4617):1297-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6310752" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenal Medulla/enzymology ; Animals ; Brain/*metabolism ; Cell Membrane/metabolism ; Cerebral Cortex/enzymology ; Epinephrine/*physiology ; Female ; Hypothalamus/enzymology ; Medulla Oblongata/enzymology ; Phenylethanolamine N-Methyltransferase/metabolism ; Pons/enzymology ; Rats ; Rats, Inbred Strains/*metabolism ; Receptors, Adrenergic/*metabolism ; Receptors, Adrenergic, alpha/*metabolism ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Relative brain size and metabolism in mammals (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-06-17
    Description: Comparisons of the relation between brain and body weights among extant mammals show that brain sizes have not increased as much as body sizes. Interspecific increases in brain and body size appear to occur at the same rate, however, when the amount of available energy is taken into account. After this adjustment, brains of primates are slightly larger than expected from the overall mammalian data, but primates also use a larger proportion of their total energy reserves for their brains. Analyses of relative brain size must take into account the requirements that the metabolically active brain has for the body.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Armstrong, E -- New York, N.Y. -- Science. 1983 Jun 17;220(4603):1302-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6407108" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Basal Metabolism ; Body Weight ; Cats ; Chiroptera/anatomy & histology ; Dogs ; Haplorhini/anatomy & histology ; Humans ; Mammals/*anatomy & histology/metabolism ; Primates/anatomy & histology ; Rats ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Cell-to-cell transfer of interferon-induced antiproliferative activity (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-02
    Description: Interferon-treated cells rapidly and efficiently transferred the antiproliferative activity of interferon to untreated cells. This phenomenon was not due to the carry-over of interferon by the interferon-treated cells. Thus, to evoke an antiproliferative state, interferon did not directly contact each cell in a population. The results suggest a novel mechanism by which interferon may indirectly regulate cell growth, and suggests that cells other than those of the immune system may play a role in controlling tumor growth in tissue where cell-to-cell contact occurs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lloyd, R E -- Blalock, J E -- Stanton, G J -- 03348/PHS HHS/ -- AM 30046/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1983 Sep 2;221(4614):953-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6192500" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Cell Communication ; Cell Division/*drug effects ; Cells, Cultured ; Humans ; Interferons/*pharmacology ; Leukemia L1210 ; Mice ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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