ALBERT

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Daniel J. Twedt, R. Randy Wilson This data article contains data collected from 2006–2012 in forests located on 31 State or Federal conservation lands in or adjacent to the Mississippi Alluvial Valley. We present the location, treatment type, and silvicultural age of data collection locations. Presented data on bird detections and forest habitat were collected during avian point counts and associated forest habitat plots and linked to the publication (D.J. Twedt and R.R. Wilson, 2017) [5] .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Juliette A. Aka, Ezequiel-Luis Calvo, Sheng-Xiang Lin The data presented here are related to the research article entitled “Estradiol-independent modulation of breast cancer transcript profile by 17beta-hydroxysteroid dehydrogenase type 1” (J.A. Aka, E.L. Calvo, S.X. Lin, 2016) [1]. We evaluated the effect of the steroidal enzyme 17β-HSD1 and its product, the estrogenic hormone 17-beta-estradiol (E2), on gene transcription profile of breast cancer cells. RNA interference technique was used to knock down the 17β-HSD1 gene ( HSD17B1 ) in the hormone-dependent breast cancer cell line T47D in steroid-deprived medium. Transfected cells were subsequently treated with E2, and microarray analyses (with three contrasts) were used to investigate (i) the effect of 17β-HSD1 expression on breast cancer cell transcript profile in steroid-deprived condition, (ii) the effect of E2 on breast cancer gene expression and (iii) if E2 affects gene regulation by 17β-HSD1. Functional enrichments of the differentially expressed genes were assessed using Ingenuity Pathway Analysis (IPA). Here, we showed data on 140 genes that are induced or repressed 1.5 time or higher ( p 〈 0.05) in the HSD17B1- silenced and E2-treated T47D cells revealed by microarray analysis, and presented the 14 functional terms found in the cancer and in the cell death and survival categories revealed by the IPA biological function analysis. Data on IPA Canonical Pathway and network analyses is also presented. Further discussion on gene regulation by 17β-HSD1 and E2 is provided in the accompanying publication [1].

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Safiétou Sanfo, M. William Fonta, Ibrahim Boubacar, P.A. John Lamers This article describes two datasets generated from various sources in south western Burkina Faso to identify the key climate and environmental drivers that cause farmers to migrate. The survey sampling is random but reasoned and rational. The first dataset from 367 farm households 1 1 100 interviewed households, and 10 Focus Group Discussions comprising 267 farmers. contains data on farmers’ perception of climate change risks or hazards, their impacts on farmland productivity and farm households’ risk management strategies. The second dataset from 58 farm households contains data on agricultural practices, environmental changes, and environmental migration. Three supplemental Excel sheets show the results of the surveys. Details on the sample as well as further interpretation and discussion of the surveys are available in the associated research article (‘Field Facts for Crop Insurance Design: Empirical Evidence from South Western Burkina Faso’ (W. M. Fonta, S. Sanfo, B. Ibrahim, B. Barry, 2015) [ 1 ]).

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Minoru Ito, Kazuhiro Minami, Yoshimasa Sagane, Toshihiro Watanabe, Koichi Niwa Here, we present data on the effects of emu oil, obtained from emu ( Dromaius novaehollandiae ) fat deposits, on melanogenesis in B16F1 murine melanoma cells. The cells were cultured in media containing different concentrations of emu oil, and the melanin content of these cells was measured using a microplate reader. Next, melanin content was measured for cells cultured with α-melanocyte-stimulating hormone. This article reports the different melanin contents as μg melanin/mg cellular protein, by using bar graphs with error bars. The present data imply that emu oil reduces the cellular melanin production.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Fereshte Babaahmadi, Sina Dobaradaran, Abdolrahim Pazira, Seyed Sajjad Eghbali, Maryam Khorsand, Mozhgan Keshtkar In this paper, we measured the levels of metals including Pb, Cr, Cd, Ni, Hg, Fe, and Cu in the inlet and outlet wastewater of hospitals. The samples were taken from wastewater in Bushehr׳s province hospitals, Iran. After the collection of samples, the concentration levels of metals were determined by using graphite furnace absorption spectrometer (AAS) method (Varian, SpectrAA 240, Australia). Statistical analysis of the data was carried out using Special Package for Social Sciences (SPSS 16).

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Svetlana Proskurina, Jussi Heinimö, Mirja Mikkilä, Esa Vakkilainen This article contains data related to the research article entitled “A survey analysis of the wood pellet industry in Finland: Future perspectives" (S. Proskurina, E. Alakangas, J. Heinimö, M. Mikkilä, E. Vakkilainen, 2016) [1]. The dataset include information about the importance of wood pellets on the global bioenergy development and role of wood pellets on the Finnish bioenergy development. Data leads to an expansion of knowledge and discoveries of new possibility for wood pellets industry analysis.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Nico Bauer, Jérôme Hilaire, Robert J. Brecha, Jae Edmonds, Kejun Jiang, Elmar Kriegler, Hans-Holger Rogner, Fabio Sferra The data files contain the assumptions and results for the construction of cumulative availability curves for coal, oil and gas for the five Shared Socioeconomic Pathways. The files include the maximum availability (also known as cumulative extraction cost curves) and the assumptions that are applied to construct the SSPs. The data is differentiated into twenty regions. The resulting cumulative availability curves are plotted and the aggregate data as well as cumulative availability curves are compared across SSPs. The methodology, the data sources and the assumptions are documented in a related article (N. Bauer, J. Hilaire, R.J. Brecha, J. Edmonds, K. Jiang, E. Kriegler, H.-H. Rogner, F. Sferra, 2016) [1] under DOI: http://dx.doi.org/10.1016/j.energy.2016.05.088 .

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Ekta Saini, V.P. Khanagwal, Rajvinder Singh Verdict on tracing exact place of drowning is a part of medico-legal investigation. This question often stands when circumstances remain unclear about true drowning place. Usually, when a dead body rises from the bottom of drowning site, it will appear near to the point where it had actually disappeared but rapid current may carry a body to real distance from the exact place of death before any major obstruction. Forensic methodology has suggested qualitative as well as quantitative comparison of diatoms recovered in dead body and reference water samples to corroborate drowning as cause of death and locating precise place of drowning. Collection of wrong reference water samples from drowning site can also hamper the investigation process. Since, the distributions of different genera in certain extents relate particular water where the death due to drowning might have taken place; therefore, the present attempt was made to understand diatom distribution in five water bodies of Haryana with reference to diatom growth factors. This research data represents diatomological profiles of selected sites for possible application of forensic diatomology. Both, the light and scanning electron microscopy identified diatoms. It is envisioned that this data report is informative enough for the experts to plan future strategy for investigating mysteries associating place of drowning.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Chien-Hua Huang, Ping-Hsun Yu, Min-Shan Tsai, Po-Ya Chuang, Tzung-Dau Wang, Chih-Yen Chiang, Wei-Tien Chang, Matthew Huei-Ming Ma, Chao-Hsiun Tang, Wen-Jone Chen The data presented in this article are related to the research article entitled “Acute Hospital Administration of Amiodarone and/or Lidocaine in Shockable Patients Presenting with Out-of-hospital Cardiac Arrest: A Nationwide Cohort Study” (C.H. Huang, P.H. Yu, M.S. Tsai et al., 2016) [1] . The data contains the information of co-morbidities coding from ICD-9 CM codes and specific difference in requirement between medical centers and non-medical centers in resuscitation. Univariate and multivariate logistic regression analysis for factors related to the outcome of survival to ICU admission and survival to hospital discharge are included in the data set. The data also contains bootstrap sensitivity analysis of the logistic regression model for survival to ICU admission and hospital discharge outcomes in out-of-hospital cardiac arrest. Subgroup analysis of epinephrine dosage related to outcome of one-year survival is shown.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Mehdi Ebrahimi, Michael Botelho The data presented in this article are related to the research article entitled “Biphasic calcium phosphates bioceramics (HA/TCP): Concept, physicochemical properties and the impact of standardization of study protocols in biomaterials research” [1] . This article provides in depth study of BCP bone substitutes as valuable option in the field of tissue engineering. However, there are discrepancies in the literature regarding the ideal physicochemical properties of BCP and the ideal balance between different phase compositions for enhanced bone tissue engineering (M. Ebrahimi, M.G. Botelho, S.V. Dorozhkin, 2016; M. Ebrahimi, P. Pripatnanont, S. Suttapreyasri, N. Monmaturapoj, 2014) [ 1 , 2 ]. This is found to be mainly because of improper characterization of BCP bioceramics in basic studies and lack of standard study protocols in in vitro and in vivo research. This data article along with original article provide the basic data required for ideal characterization of BCP and other bioceramics in an attempt to provide basic standardized protocols for future studies.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Ya-Chuan Hsiao, Tsung-Lin Yang The lacrimal gland is responsible for tear synthesis and secretion, and is derived from the epithelia of ocular surface and generated by branching morphogenesis. The dataset presented in this article is to support the research results of the effect of chitosan biomaterials on facilitating the structure formation of the lacrimal gland by regulating temporospatial dynamics of morphogen. The embryonic lacrimal gland explants were used as the standard experimental model for investigating lacrimal gland branching morphogenesis. Chitosan biomaterials promoted lacrimal gland branching with a dose-dependent effect. It helped in vivo binding of hepatocyte growth factor (HGF) related molecules in the epithelial-mesenchymal boundary of emerging epithelial branches. When mitogen-activated protein kinase (MAPK) or protein kinase B (Akt/PKB) inhibitors applied, the chitosan effects reduced. Nonetheless, the ratios of MAPK and Akt/PKB phosphorylation were still greater in the chitosan group than the control. The data demonstrated here confirm the essential role of HGF-signaling in chitosan-promoted structure formation of the lacrimal gland.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Weijun Xu, Guifang Liu, Hongyi Li This article contains datasets related to the research article titled a novel jump diffusion model based on SGT distribution and its applications (”A novel jump diffusion model based on SGT distribution and its applications” (W.J. Xu, G.F. Liu, H.Y. Li, 2016) [1] ). The datasets contain continuous composite daily percentage return values which are computed from the daily closing prices. Firstly, we describe statistical properties of the datasets. Then, the datasets are split into two samples, the in-sample data and out-of-sample data. The datasets can be used as benchmarks for testing the performances of jump diffusion models.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): A.J. Bates, A. Comerford, R. Cetto, D.J. Doorly, R.C. Schroter, N.S. Tolley Computational Fluid Dynamics (CFD) is fast becoming a useful tool to aid clinicians in pre-surgical planning through the ability to provide information that could otherwise be extremely difficult if not impossible to obtain. However, in order to provide clinically relevant metrics, the accuracy of the computational method must be sufficiently high. There are many alternative methods employed in the process of performing CFD simulations within the airways, including different segmentation and meshing strategies, as well as alternative approaches to solving the Navier–Stokes equations. However, as in vivo validation of the simulated flow patterns within the airways is not possible, little exists in the way of validation of the various simulation techniques. The data presented here consists of very highly resolved flow data. The degree of resolution is compared to the highest necessary resolutions of the Kolmogorov length and time scales. Therefore this data is ideally suited to act as a benchmark case to which cheaper computational methods may be compared. A dataset and solution setup for one such more efficient method, large eddy simulation (LES), is also presented.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Abeed Sarker, Graciela Gonzalez In this data article, we present to the data science, natural language processing and public heath communities an unlabeled corpus and a set of language models. We collected the data from Twitter using drug names as keywords, including their common misspelled forms. Using this data, which is rich in drug-related chatter, we developed language models to aid the development of data mining tools and methods in this domain. We generated several models that capture (i) distributed word representations and (ii) probabilities of n-gram sequences. The data set we are releasing consists of 267,215 Twitter posts made during the four-month period—November, 2014 to February, 2015. The posts mention over 250 drug-related keywords. The language models encapsulate semantic and sequential properties of the texts.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Amir Mostafaei, Eamonn T. Hughes, Colleen Hilla, Erica L. Stevens, Markus Chmielus Binder jet printing (BJP) is a metal additive manufacturing method that manufactures parts with complex geometry by depositing powder layer-by-layer, selectively joining particles in each layer with a polymeric binder and finally curing the binder. After the printing process, the parts still in the powder bed must be sintered to achieve full densification (A. Mostafaei, Y. Behnamian, Y.L. Krimer, E.L. Stevens, J.L. Luo, M. Chmielus, 2016; A. Mostafaei, E. Stevens, E. Hughes, S. Biery, C. Hilla, M. Chmielus, 2016; A. Mostafaei, Y. Behnamian, Y.L. Krimer, E.L. Stevens, J.L. Luo, M. Chmielus, 2016) [1 – 3] . The collected data presents the characterization of the as-received gas- and water-atomized alloy 625 powders, BJP processing parameters and density of the sintered samples. The effect of sintering temperatures on the microstructure and the relative density of binder jet printed parts made from differently atomized nickel-based superalloy 625 powders are briefly compared in this paper. Detailed data can be found in the original published papers by authors in (A. Mostafaei, J. Toman, E.L. Stevens, E.T. Hughes, Y.L. Krimer, M. Chmielus, 2017) [4].

Description: Publication date: Available online 3 December 2016 Source: Data in Brief Author(s): Eriko Maeda, Nobuo Tomizawa, Shigeaki Kanno, Koichiro Yasaka, Takatoshi Kubo, Kenji Ino, Rumiko Torigoe, Kuni Ohtomo The data presented in this articles are related to the research article entitled “The feasibility of Forward-projected model-based Iterative Reconstruction SoluTion (FIRST) for coronary 320-row computed tomography angiography: a pilot study” (E. Maeda, N. Tomizawa, S. Kanno, K. Yasaka, T. Kubo, K. Ino, R. Torigoe, K. Ohtomo, 2016) [1] . This article describes subjective and objective evaluations of 2 mm–4 mm coronary artery phantom scanned with 100% dose and reconstructed with hybrid iterative reconstruction, and 90%, 80% and 70% dose reconstructed with full iterative reconstruction.

Description: Publication date: Available online 3 December 2016 Source: Data in Brief Author(s): Ake Vastermark, Adelle Driker, Jingwei Weng, Xiaochun Li, Jiawei Wang, Milton H. Saier We introduce the value of information obtained by comparing alternative crystal forms of the same sub-state (of outward open UlaA, our example protein), which is found in the same lattice configuration but different space groups. We compare instability estimates obtained using this new method (alternative crystal forms) with temperature factors. Using a transport assay result, we correlate observations for two homologous secondary structure elements, and show that the alternative states method for obtaining instability estimates provide differentiating information about an important and immobilized mid-TMS region. The data presented in this article are related to the article entitled “The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism” (Vastermark et al ., 2016 [1] ).

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Mehdi Ahmadi, Moloud Dashtestani, Afshin Takdastan, Sahand Jorfi, Bahman Ramavandi Oil drill cuttings are challenging wastes in oil sites especially in Khuzestan province, a major oil producing region in Iran. As co- composting is a simple and eco- friendly technique for bioremediation of oil base drill cutting, this data article designed to describe co- composting of oil base drill cutting with cow manure. The data suggest that with optimized mixture of cow manure/oily drill wastes (here, 20:1) could engender more effective treatment of the wastes (with final total petroleum hydrocarbon of 0.01 g/Kg). The data will be informative for oil drilling companies and environmental agencies for choosing it as a practical bioremediation process of soil/wastes polluted by petroleum hydrocarbons.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Juan A. Ragazzo-Sánchez, Ramsés R. González-Estrada, Martha A. Santana-Martínez, María del Carmen Wacher-Rodarte, Carlos A. Eslava-Campos, Montserrat Calderón-Santoyo Abiotic factors influenced the capacity of the strains to form biofilms. Classification of the adhesion type is related with the optical density measured on the biofilm formation of tested strains. The relationship between the biofilm formation in real values with theoretical values of the strains was used to determine the mechanism involved during mixed cultures.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Peter N. Eze, Valiant S. Mosokomani, Theophilus K. Udeigwe, Opeoluwa F. Oyedele, Adeniyi F. Fagbamigbe Geospatial dataset of trace elements including manganese (Mn), iron (Fe), titanium (Ti), rubidium (Rb), strontium (Sr), thorium (Th), Vanadium (V) and Zirconium (Zr) of near-surface soils in a Cu–Ni prospecting field at Airstrip North, Central Botswana were statistically analysed. Grid sampling method was used in the field data collection. The relatively new portable X-ray fluorescence spectrometer (Delta Premium, 510890, USA) technology in a “soil” mode was used to measure the concentrations of trace elements in the soils. The data presented was obtained from the average reading of two soil samples collected from same point but passed through sieves. Sequel to DOI: 10.1016/j.dib.2016.08.026 (P.N. Eze, V.S. Mokosomani, T.K. Udeigwe, O.F. Oyedele, 2016) [1].

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Lorena Giordano, Denis Roizard, Roda Bounaceur, Eric Favre The article describes data concerning the separation performances of polymeric hollow-fiber membranes. The data were obtained using a model for simulating gas separation, described in the research article entitled “Interplay of inlet temperature and humidity on energy penalty for CO 2 post-combustion capture: rigorous analysis and simulation of a single stage gas permeation process” (L. Giordano, D. Roizard, R. Bounaceur, E. Favre, 2016) [1] . The data were used to validate the model by comparison with literature results. Considering a membrane system based on feed compression only, data from the model proposed and that from literature were compared with respect to the molar composition of permeate stream, the membrane area and specific energy requirement, varying the feed pressure and the CO 2 separation degree.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): J.-P. Rossi, V. Imbault, T. Lamant, J. Rousselet The dataset supplied in this article provides the spatial location and the species composition of urban trees belonging to three coniferous genera ( Pinus , Cedrus and Pseudotsuga ) inventoried in 5 districts of the city of Orléans (France). A total of 9321 trees were georeferenced. The most abundant species was the black pine Pinus nigra for which a total of 2420 trees were observed. Other common species were the scots pine P. sylvestris , the Douglas-fir Pseudotsuga menziesii and different species of the genus Cedrus . The data supplied in this article are related to “A citywide survey of the pine processionary moth Thaumetopoea pityocampa spatial distribution in Orléans (France)” by J.-P. Rossi, V. Imbault, T. Lamant, J. Rousselet,) [3] .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Panagiotis G. Asteris The fundamental period of vibration appears to be one of the most critical parameters for the seismic design of buildings because it strongly affects the destructive impact of the seismic forces. In this article, important research data (entitled FP4026 Research Database (Fundamental Period-4026 cases of infilled frames) based on a detailed and in-depth analytical research on the fundamental period of reinforced concrete structures is presented. In particular, the values of the fundamental period which have been analytically determined are presented, taking into account the majority of the involved parameters. This database can be extremely valuable for the development of new code proposals for the estimation of the fundamental period of reinforced concrete structures fully or partially infilled with masonry walls.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Nannan Chen, Mouming Zhao, Christophe Chassenieux, Taco Nicolai The data presented in this article are related to the research article entitled Structure of Self-assembled Native Soy Globulin in Aqueous Solution as a Function of the Concentration and the pH by N. Chen, M. Zhao C. Chassenieux, T. Nicolai (2016) [1]. Please refer to this article for interpretation of the data. The protein composition of soy protein isolate (SPI) was characterized by SDS-Page. The molar mass of native soy globulin aggregates formed at different protein concentrations was determined by light scattering as a function of the waiting time. The dependence of the pH on the net charge density of native soy globulins was determined for solutions containing 5 g/L or 2 g/L SPI.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Christopher T. Rota, Alexander J. Wolf, Rochelle B. Renken, Robert A. Gitzen, Debby K. Fantz, Robert A. Montgomery, Matthew G. Olson, Larry D. Vangilder, Joshua J. Millspaugh We present predictor variables and R and Stan code for simulating and analyzing counts of Missouri Ozark herpetofauna in response to three forest management strategies. Our code performs four primary purposes: import predictor variables from spreadsheets; simulate synthetic response variables based on imported predictor variables and user-supplied values for data-generating parameters; format synthetic data for export to Stan; and analyze synthetic data.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Anna Siri, Hicham Khabbache, Ali Al-Jafar, Mariano Martini, Francesco Brigo, Nicola Luigi Bragazzi The present data article describes high-school drop-out related web activities in Canada, from 2004 to 2012, obtained mining Google Trends (GT), using high-school drop-out as key-word. The searches volumes were processed, correlated and cross-correlated with statistical data obtained at national and province level and broken down for gender. Further, an autoregressive moving-average (ARMA) model was used to model the GT-generated data. From a qualitative point of view, GT-generated relative search volumes (RSVs) reflect the decrease in drop-out rate. The peak in the Internet-related activities occurs in 2004 (56.35%, normalized value), and gradually declines to 40.59% (normalized value) in 2007. After, it remains substantially stable until 2012 (40.32%, normalized value). From a quantitative standpoint, the correlations between Canadian high-school drop-out rate and GT-generated RSVs in the study period (2004–2012) were statistically significant both using the drop-out rate for academic year and the 3-years moving average. Examining the data broken down by gender, the correlations were higher and statistically significant in males than in females. GT-based data for drop-out resulted best modeled by an ARMA(1,0) model. Considering the cross correlation of Canadian regions, all of them resulted statistically significant at lag 0, apart from for New Brunswick, Newfoundland and Labrador and the Prince Edward island. A number or cross-correlations resulted statistically significant also at lag −1 (namely, Alberta, Manitoba, New Brunswick and Saskatchewan).

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Benjamin Rey, Cyril Dégletagne, Claude Duchamp In this article, we present differentially expressed gene profiles in the pectoralis muscle of wild juvenile king penguins that were either naturally acclimated to cold marine environment or experimentally immersed in cold water as compared with penguin juveniles that never experienced cold water immersion. Transcriptomic data were obtained by hybridizing penguins total cDNA on Affymetrix GeneChip Chicken Genome arrays and analyzed using maxRS algorithm , “ Transcriptome analysis in non-model species: a new method for the analysis of heterologous hybridization on microarrays ” (Dégletagne et al., 2010) [1] . We focused on genes involved in multiple antioxidant pathways. For better clarity, these differentially expressed genes were clustered into six functional groups according to their role in controlling redox homeostasis. The data are related to a comprehensive research study on the ontogeny of antioxidant functions in king penguins, “Hormetic response triggers multifaceted anti-oxidant strategies in immature king penguins (Aptenodytes patagonicus)” (Rey et al., 2016) [2] . The raw microarray dataset supporting the present analyses has been deposited at the Gene Expression Omnibus (GEO) repository under accessions GEO: GSE17725 and GEO: GSE82344 .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Patricia Bianca Clissa, Rodrigo Pessôa, Karla Fernanda Ferraz, Daniela Raguer Valadão de Souza, Sabri Saeed Sanabani This article describes the data on the global expression profile of small RNA (smRNAs) molecules in mice gastrocnemius muscle exposed to jararhagin, snake venom metalloproteinase. The data include smRNAs in mice gastrocnemius muscle challenged with Jararhagin (Jar; n =4) in the right paw or phosphate-buffered saline (PBS; control; n =4) in the left paw. smRNA-Seq libraries were generated after 24 h of exposure to PBS or jararhagin. The expression profiles of smRNAs including microRNA and snoRNA were compared between both groups. The sequencing data from both groups have been uploaded to Zenodo http://dx.doi.org/10.5281/zenodo.56492 .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Annabell Plauth, Anne Geikowski, Susanne Cichon, Sylvia J. Wowro, Linda Liedgens, Morten Rousseau, Christopher Weidner, Luise Fuhr, Magdalena Kliem, Gail Jenkins, Silvina Lotito, Linda J. Wainwright, Sascha Sauer We show here if under physiologically relevant conditions resveratrol (RSV) remains stable or not. We further show under which circumstances various oxidation products of RSV such as ROS can be produced. For example, in addition to the widely known effect of bicarbonate ions, high pH values promote the decay of RSV. Moreover, we analyse the impact of reduction of the oxygen partial pressure on the pH-dependent oxidation of RSV. For further interpretation and discussion of these focused data in a broader context we refer to the article “Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress” (Plauth et al., in press) [1] .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Kallirroi Voudouri, Dragana Nikitovic, Aikaterini Berdiaki, John Tsiaoussis, Dimitris Kletsas, Nikos K. Karamanos, George N. Tzanakakis In this data article, the potential role of p53 tumor suppressor gene (p53) on the attachment ability of MCF-7 breast cancer cells was investigated. In our main article, “IGF-I/ EGF and E2 signaling crosstalk through IGF-IR conduit point affect breast cancer cell adhesion” (K. Voudouri, D. Nikitovic, A. Berdiaki, D. Kletsas, N.K. Karamanos, G.N. Tzanakakis, 2016) [1], we describe the key role of IGF-IR in breast cancer cell adhesion onto fibronectin (FN). p53 tumor suppressor gene is a principal regulator of cancer cell proliferation. Various data have demonstrated an association between p53 and IGF-IR actions on cell growth through its’ putative regulation of IGF-IR expression. According to our performed experiments, p53 does not modify IGF-IR expression and does not affect basal MCF-7 cells adhesion onto FN. Moreover, technical details about the performance of adhesion assay onto the FN substrate were provided.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Yum Eryanti, Adel Zamri, Neni Frimayanti, Unang Supratman, Tati Herlina The dataset of curcumin derivatives consists of 45 compounds ( Table 1 ) with their anti cancer biological activity (IC 50 ) against P388 cell line. 45 curcumin derivatives were used in the model development where 30 of these compounds were in the training set and the remaining 15 compounds were in the test set. The development of the QSAR model involved the use of the multiple linear regression analysis (MLRA) method. Based on the method, r 2 value, r 2 (CV) value of 0.81, 0.67 were obtained. The QSAR model was also employed to predict the biological activity of compounds in the test set. Predictive correlation coefficient r 2 values of 0.88 were obtained for the test set.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Olujide O. Olubiyi, Birgit Strodel In this article we provide a data package containing the topology files and parameters compatible with the CHARMM22 force field for thirteen non-natural amino acids. The force field parameters were derived based on quantum mechanical (QM) calculations involving geometry optimization and potential energy surface scanning at the HF 6-31G( d ) and HF 6-311G( d,p ) levels of theory. The resulting energy data points were fitted to mathematical functions representing each component of the CHARMM22 force field. Further fine-tuning of the parameters utilized molecular mechanics energies, which were iteratively calculated and compared to the corresponding QM values until the latter were satisfactorily reproduced. The final force field data were validated with molecular dynamics simulations in explicit solvent conditions.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Mahmoud Masoud, Erhan Kozan, Geoff Kent, Shi Qiang Liu The freight rail systems have an essential role to play in transporting the commodities between the delivery and collection points at different locations such as farms, factories and mills. The fright transport system uses a daily schedule of train runs to meet the needs of both the harvesters and the mills (An Integrated Approach to Optimise Cane Rail Operations (M. Masoud, E. Kozan, G. Kent, Liu, Shi Qiang, 2016b) [1]). Producing an efficient daily schedule to optimise the rail operations requires integration of the main elements of harvesting, transporting and milling in the value chain of the Australian agriculture industry. The data utilised in this research involve four main tables: sidings, harvesters, sectional rail network and trains. The utilised data were collected from Australian sugar mills as a real application. Operations Research techniques such as metaheuristic and constraint programming are used to produce the optimised solutions in an analytical way.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Quan-Hoang Vuong, Trong-Khang Nguyen The research process started in the first week of August 10, 2014 and ended early February 2015, obtaining qualified data for 330 patients from many hospitals in northern Vietnam. Its expansion was performed for an enlarged dataset through May 2015, containing 900 records. This article exemplifies the attempt to examine the likelihood of destitution among Vietnamese patients due to insufficient insurance coverage, cost of treatment and patient׳s status of residency during a curative hospital stay. The result suggests that the patients, who are poor and come from rural areas, face serious obstacles in accessing health care services. This data article presents attributes and values of the data set used in the article provided at DOI: http://dx.doi.org/10.1186/s40064-015-1279-x Vuong (2015) [4].

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Ashish B. Deshpande, Hemangi G. Chidley, Pranjali S. Oak, Keshav H. Pujari, Ashok P. Giri, Vidya S. Gupta Data in this article presents fatty acid composition of three mango cultivars; Alphonso, Pairi and Kent through fruit development and ripening. Change in the ω-6 and ω-3 fatty acids level during mango fruit development and ripening is depicted. Also, data on aroma volatile ‘lactones’ composition from pulp and skin tissues of these cultivars at their ripe stage, respectively is provided. Statistical data is also shown, which correlates modulation in lactone content with that of fatty acid composition and content during fruit development and ripening in all the three mango cultivars.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Giti Akhavan, Sina Dobaradaran, Jaleh Mohajeri Borazjani In the present data article, fluoride concentration levels of drinking water (with spring or groundwater sources) in 10 villages of Asara area located in Alborz province were determined by the standard SPADNS method using a spectrophotometer (DR/2000 Spectrophotometer, USA). Daily fluoride intakes were also calculated based on daily drinking water consumption. The fluoride content were compared with EPA and WHO guidelines for drinking water.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Farshid Soleimani, Sina Dobaradaran, Abdolreza Hayati, Maryam Khorsand, Mozhgan Keshtkar In this article, we determined the concentration levels of metals including Zn, Al, Sr, and Co and metalloid of As of ballast water in commercial ships entering Bushehr port, along the Persian Gulf. Ballast water samples were taken from commercial ships entering Bushehr port from 34 ports around the world during 15 February and 25 August 2016. The concentration levels of metals and metalloid were determined by using a graphite furnace absorption spectrometer (AAS).

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Silvia Angeloni This article contains data concerning the movement of extra-EU asylum seekers in Europe. Data used in this paper were collected from the Eurostat database and the UNHCR database. The data consist of some socio-economic features related to 30 European countries where extra-EU asylum seekers have applied for protection. All variables were transformed into their natural logs. The degree of statistical correlation is evaluated from Pearson׳s coefficient, using the 0.05 level of significance. Regression analysis is conducted to identify some socio-economic predictors of countries attracting asylum migration. Six models are presented, where ‘first time asylum applicants’ in 2015 (1,324,215 individuals) in 30 European countries were regressed on 2014 predictors. The multilinear regression model was tested by using data on asylum seekers in 2014, regressed on the same predictors referred to 2013. The data here shared provide a resource for researchers working in the topical field of migration.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Won-Mo Yang, Kyung-Ho Min, Wan Lee Certain microRNAs (miRNAs) targeting the molecules in the insulin signaling cascades are dysregulated by saturated fatty acids (SFA), which can lead to insulin resistance and type 2 diabetes. This article reports the accompanying data collected using miRNAs microarrays to identify the changes in miRNA expression in HepG2 cells treated with SFA palmitate. Differentially expressed miRNA analyses in HepG2 cells showed that a range of upregulated (>1.5-fold) or downregulated (〈0.5-fold) miRNAs. Further extensive insights into the implications of miRNAs, particularly miR-1271, in HepG2 cells can be found in "MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells" (W.M. Yang, K.H. Min, W. Lee, 2016) [1].

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Wanessa Cardoso da Silva, Telma M. Oshiro, Daniel Coelho de Sá, Dilcilea D.G.S. Franco, Cyro Festa Neto, Alessandra Pontillo This article presents data related to our another article entitled, Genotyping and differential expression analysis of inflammasome genes in sporadic malignant melanoma reveal novel contribution of CARD8, IL1B and IL18 in melanoma susceptibility and progression ( W.C. Silva, T.M. Oshiro, D.C. Sá, D.D.G.S. Franco, C. Festa Neto, A. Pontillo , 2016) [2] . Data presented here refers to the distribution of selected inflammasome SNPs in a Brazilian case/control cohort. We have identified 4 inflammasome related Single Nucleotide Polymorphisms (SNPs) for CARD8 (rs6509365); IL1B (rs1143643) and IL18 (rs5744256 and rs1834481) related to melanoma susceptibility/protection. This data can serve as a potential prognostic marker in sporadic malignant melanoma.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): M. Colby Hunter, Alex E. Pozhitkov, Peter A. Noble This article provides supporting data for the research article ‘Microbial Signatures of Oral Dysbiosis, Periodontitis and Edentulism Revealed by Gene Meter Methodology’ (M.C. Hunter, A.E. Pozhitkov, P.A. Noble, 2016) [1]. In that article, we determined the microbial abundance signatures for patient with periodontics, edentulism, or health using Gene Meter Technology. Here we provide the data used to make the DNA microarray and the resulting microbial abundance data that was determined using the calibrated probes and the 16S rRNA genes harvested from patients. The first data matrix contains two columns: one is the GenInfo Identifier (GI) numbers of the 16S rRNA gene sequences and the other is the corresponding oral bacterial taxonomy. The probes were then screened for redundancy and if they were found to be unique, they were synthesized onto the surface of the DNA microarrays. The second data matrix consists of the abundances of the 576 16S rRNA genes that was determined using the median value of all individual calibrated probes targeting each gene. The data matrix consists of 16 columns and 576 rows, with the columns representing the 16 patients and the rows representing 576 different oral microorganisms. The third data matrix consists of the abundances of 567 16S rRNA genes determined using the calibrated abundance of all aggregated probes targeting the same 16S rRNA gene. The data matrix of the aggregated probes consists of 16 samples and 567 rows.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Zeynep Ozdemir, Gul Bahar Basim Bioactivity of titanium depends on the quality and characteristics of its surface oxide film. Through implementation of chemical mechanical polishing (CMP) process on titanium plates, a protective oxide (titania) film grows on the titanium based implant surface. In this article, surface properties of the titanium oxide are investigated as a function of the CMP process conditions. Surface responses were evaluated in terms of wettability, nano-scale surface roughness and material removal rates (MRR). Surface chemical compositions were also evaluated through Fourier transform infrared spectroscopy (FT-IR).

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Kylie G. Bendele, Felix D. Guerrero, Connor Cameron, Adalberto A. Perez de Leon The New World Screwworm (NWS), Cochliomyia hominivorax , is a pest insect that is endemic to subtropical and tropical regions of the Western Hemisphere. The female lays eggs in open wounds or orifices of warm-blooded animals. Upon hatching, the resulting larvae feed upon the host׳s living tissues, which can become infected and death can occur. The sterile insect technique was developed to eradicate this pest from North America and new female conditional-lethal strains that generate only male individuals are being developed for use in the eradication program. To facilitate the identification of useful transcripts and gene promoters for these new strains, we used an Illumina Hi-Seq protocol to sequence the testes transcriptome of NWS. We report the assembly of 4149 transcripts (≥200 nt) from testes dissected from NWS males obtained from the J06 strain used in the screwworm production plant in Pacora, Panama. Functional annotation resulted in 2060, 2031, 558, and 325 transcripts with assigned BlastX, Gene Ontology, Enzyme Codes, and KEGG pathway information, respectively. In the Gene Ontology annotations, 6% and 3% of the transcripts in the Biological Process Ontology were noted as Developmental Process and Reproduction, respectively. This data set will serve as a resource to facilitate studies of sex determination in the NWS and the development of recombinant vectors that can be used to create new male-only strains of NWS.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): John Asafu-Adjaye, Dominic Byrne, Maximiliano Alvarez The data presented in this article are related to the research article entitled ‘Economic Growth, Fossil Fuel and Non-Fossil Consumption: A Pooled Mean Group Analysis using Proxies for Capital’ (J. Asafu-Adjaye, D. Byrne, M. Alvarez, 2016) [1] . This article describes data modified from three publicly available data sources: the World Bank׳s World Development Indicators ( http://databank.worldbank.org/data/reports.aspx?source=world-development-indicators ), the U.S. Energy Information Administration׳s International Energy Statistics ( http://www.eia.gov/cfapps/ipdbproject/IEDIndex3.cfm?tid=44&pid=44&aid=2 ) and the Barro-Lee Educational Attainment Dataset ( http://www.barrolee.com ). These data can be used to examine the relationships between economic growth and different forms of energy consumption. The dataset is made publicly available to promote further analyses.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Geethakumari Konathala, Ramesh Mandarapu, Sudhakar Godi X-ray repair cross-complementing group 1 (XRCC1) is a major DNA repair gene involved in BER mutation. Polymorphisms in DNA repair genes associated with repair efficiency against DNA damage may predispose an individual׳s cancer susceptibility. Data from cervical cancer patients was collected from South Indian Women. Genotyping of XRCC1 polymorphisms (194C/T, 280G/A and 399G/A) was done by polymerase-chain-reaction with the confronting-two-pair primer (PCR-CTPP) method.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Michael Petridis, Gregory M. Cook The dataset presented here describes a microarray experiment to identify the AmtR regulon of Mycobacterium smegmatis comparing the transcription profile of a M. smegmatis amtR mutant to M. smegmatis wild-type. The raw and processed microarray data are available in the ArrayExpress database under Accession Number E-MTAB-4857 and interpretation of this data is found in the research article “Structure and function of AmtR in Mycobacterium smegmatis : implications for post-transcriptional regulation of urea metabolism through a small antisense RNA” (Petridis et al., in press) [1].

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Safikur Rahman, Syed Ausaf Ali, Asimul Islam, Md. Imtaiyaz Hassan, Faizan Ahmad This paper describes data related to the research article “Testing the dependence of stabilizing effect of osmolytes on the fractional increase in the accessible surface area on thermal and chemical denaturations of proteins” [1] . Heat- and guanidinium chloride (GdmCl)-induced denaturation of three disulfide free proteins (bovine cytochrome c (b-cyt- c ), myoglobin (Mb) and barstar) in the presence of different concentrations of methylamines (sarcosine, glycine-betaine (GB) and trimethylamine-N-oxide (TMAO)) was monitored by [ ϴ ] 222 , the mean residue ellipticity at 222 nm at pH 7.0. Methylamines belong to a class of osmolytes known to protect proteins from deleterious effect of urea. This paper includes comprehensive thermodynamic data obtained from the heat- and GdmCl-induced denaturations of barstar, b-cyt- c and Mb.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Guo-Long Tan, Hao-Hao Sheng The mutual control of the electric and magnetic properties of a multiferroic solid is of fundamental and great technological importance. In this article, the synthesis procedure of La 0.2 Pb 0.7 Fe 12 O 19 ceramics was briefly described and the data acquired for the materials characterization is presented. This data article is related to the research article-Acta Mater. 2016, 121, 144 ( j.actamat.2016.08.083 ). Electric polarization hysteresis loop and I-V curve, which help to confirm the ferroelectricity of La 0.2 Pb 0.7 Fe 12 O 19 ceramics, were presented. Strong magnetic polarization data was also presented. The great variation of the dielectric constants along with the magnetic field has been presented which helped to demonstrat the giant magnetocapacitance of La 0.2 Pb 0.7 Fe 12 O 19 . All the datasets were collected at room temperature. Large ferroelectricity, strong magnetism and colossal magneto-capacitance effect have been all realized in one single phase La 0.2 Pb 0.7 Fe 12 O 19 at room temperature.

Description: Publication date: Available online 5 December 2016 Source: Data in Brief Author(s): Anna V. Naumova, Andrey E. Akulov, Marina Yu. Khodanovich, Vasily L. Yarnykh The presented dataset provides a normative high-resolution three-dimensional (3D) macromolecular proton fraction (MPF) map of the healthy rat brain in vivo and source images used for its reconstruction. The images were acquired using the protocol described elsewhere (Naumova, et al. High-resolution three-dimensional macromolecular proton fraction mapping for quantitative neuroanatomical imaging of the rodent brain in ultra-high magnetic fields. Neuroimage (2016) doi: 10.1016/j.neuroimage.2016.09.036). The map was reconstructed from three source images with different contrast weightings (proton density, T 1 , and magnetization transfer) using the single-point algorithm with a synthetic reference image. Source images were acquired from a living animal on an 11.7 T small animal MRI scanner with isotropic spatial resolution of 170 µm 3 and total acquisition time about 1.5 h. The 3D dataset can be used for multiple purposes including interactive viewing of rat brain anatomy, measurements of reference MPF values in various brain structures, and development of image processing techniques for the rodent brain segmentation. It also can serve as a gold standard image for implementation and optimization of rodent brain MRI protocols.

Description: Publication date: Available online 6 December 2016 Source: Data in Brief Author(s): Kíssila Rabelo, Monique R.O. Trugilho, Simone M. Costa, André T.S. Ferreira, Paulo C. Carvalho, Jonas Perales, Ada M.B. Alves The data supplied in this article are related to the research article entitled “The effect of the dengue non-structural 1 protein expression over the HepG2 cell proteins in a proteomic approach” (K. Rabelo, M.R. Trugillo, S.M. Costa, B.A. Pereira, O.C. Moreira, A.T. Ferreira et al ., 2016) [1] . The present article provides the inventory of peptides and proteins mapped in a hepatocyte cell line (HepG2) by mass spectrometry in the presence of the non-structural protein 1 (NS1) of Dengue 2 virus (DENV2). Cells were transfected with pcENS1 plasmid, which encodes the DENV2 NS1 protein, or the controls pcDNA3 (negative control) or pMAXGFP, encoding the green fluorescent protein (GFP), a protein unrelated to dengue. Differentially abundant protein lists were obtained by comparing cells transfected with pcENS1 and controls.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): M. Broseghini, M. D’Incau, L. Gelisio, N.M. Pugno, P. Scardi This paper contains data and supporting information of and complementary to the research article entitled “ Effect of jar shape on high-energy planetary ball milling efficiency: simulations and experiments ” (Broseghini et al.,) [1] . Calcium fluoride (CaF 2 ) was ground using two jars of different shape (cylindrical and half-moon) installed on a planetary ball-mill, exploring different operating conditions (jar-to-plate angular velocity ratio and milling time). Scanning Electron Microscopy (SEM) images and X-Ray Powder Diffraction data (XRPD) were collected to assess the effect of milling conditions on the end-product crystallite size. Due to the inhomogeneity of the end product, the Whole Powder Pattern Model (WPPM, (Scardi, 2008) [2] ) analysis of XRPD data required the hypothesis of a bimodal distribution of sizes – respectively ground (fine fraction) and less-to-not ground (coarse fraction) – confirmed by SEM images and suggested by the previous literature (Abdellatief et al., 2013) [3 , 4] . Predominance of fine fraction clearly indicates optimal milling conditions.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Anatoli Bogdan, Mario J. Molina, Heikki Tenhu The visualization data (8 movies) presented in this article are related to the research article entitled “Freezing and glass transitions upon cooling and warming and ice/freeze-concentration-solution morphology of emulsified aqueous citric acid” (A. Bogdan, M.J. Molina, H. Tenhu, 2016) [1] . The movies recorded in-situ with optical cryo-miscroscopy (OC-M) demonstrate for the first time freezing processes that occur during the cooling and subsequent warming of emulsified micrometer-scaled aqueous citric acid (CA) drops. The movies are made publicly available to enable critical or extended analyzes.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Michael R. Fellinger, Louis G. Hector Jr., Dallas R. Trinkle We present computed datasets on changes in the lattice parameter and elastic stiffness coefficients of bcc Fe due to substitutional Al, B, Cu, Mn, and Si solutes, and octahedral interstitial C and N solutes. The data is calculated using the methodology based on density functional theory (DFT) presented in Ref. (M.R. Fellinger, L.G. Hector Jr., D.R. Trinkle, 2017) [1] . All the DFT calculations were performed using the Vienna Ab initio Simulations Package (VASP) (G. Kresse, J. Furthmüller, 1996) [2] . The data is stored in the NIST dSpace repository ( http://hdl.handle.net/11256/671 ).

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): A. Emelyanov, P. Andoskin, S. Pchelina This data article presents a dataset of total, oligomeric alpha-synuclein and hemoglobin levels in plasma of drug-naïve PD patients and controls. This is the first attempt to assess the effect of hemolysis rate on oligomeric alpha-synuclein levels in peripheral plasma. The data are associated with the research article “Oligomeric alpha-synuclein and glucocerebrosidase activity levels in GBA-associated Parkinson׳s disease” (Pchelina et al., 2016) [1] .

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Chase A. Klingaman, Matthew J. Wagner, Justin R. Brown, John B. Klecker, Ethan H. Pauley, Colin J. Noldner, Jared R. Mays The data presented in this article are related to the research article, “HPLC-based enzyme kinetics assay for glucosinolate hydrolysis facilitate analysis of systems with both multiple reaction products and thermal enzyme denaturation” (C.K. Klingaman, M.J. Wagner, J.R. Brown, J.B. Klecker, E.H. Pauley, C.J. Noldner, J.R. Mays,) [1] . This data article describes (1) the synthesis and spectral characterization data of a non-natural glucosinolate analogue, 2,2-diphenylethyl glucosinolate, (2) HPLC standardization data for glucosinolate, isothiocyanate, nitrile, and amine analytes, (3) reaction progress curve data for enzymatic hydrolysis reactions with variable substrate concentration, enzyme concentration, buffer pH, and temperature, and (4) normalized initial velocities of hydrolysis/formation for analytes. These data provide a comprehensive description of the enzyme-catalyzed hydrolysis of 2,2-diphenylethyl glucosinolate ( 5 ) and glucotropaeolin ( 6 ) under widely varied conditions.

Description: Publication date: Available online 6 December 2016 Source: Data in Brief Author(s): Ala` Abdel Ali, Maie Al-Bader, Narayana Kilarkaje This article contains data related to the article “Effects of Trans-Resveratrol on hyperglycemia-induced abnormal spermatogenesis, DNA damage and alterations in poly (ADP-ribose) polymerase signaling in rat testis” (A. Abdelali, M. Al-Bader, N. Kilarkaje, 2016) [1]. The data are related to Resveratrol on diabetes-induced changes in blood glucose levels, body weights of rats, sperm count and motility, expression of poly (ADP-ribose) polymerase-1 (PARP1) in Leydig cells and in intratesticular blood vessels, and stage-dependent expression of PARP1 and Sirtuin 1 (SirT1) in the rat testis. In this experiment, the data were obtained from control, Resveratrol-treated, diabetic and Resveratrol-treated diabetic rats on day 42 after the induction of diabetes. Resveratrol treatment for a group each of normal and diabetic rats started on day 22 and extended up to day 42. The sperm parameters were conducted in samples obtained from the epididymis. The expression of proteins was evaluated by immunohistochemistry by using specific primary antibodies. The data are presented in the form of figures and significance of them has been given in the research article [1].

Description: Publication date: Available online 6 December 2016 Source: Data in Brief Author(s): Weiguo Wang, Song Chen, Wenzhe Chen This article contains the experimental data for the characterization of ∑3 boundaries in a cold deformed and annealed pure iron. Mentioned data are relevant to the research article “ The inter-connections of ∑3 boundaries in pure iron” (Weiguo Wang, Song Chen, Gregory S. Rohrer, Wenzhe Chen, 2017) [1]. The characterization of ∑3 boundaries was performed through an integrated method including electron backscatter diffraction, stereology based five parameter analysis and crystallographic analysis. This method as formulated can determine the inter-connections of any type grain boundaries with fixed misorientation.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Lina R. Nih, Pouria Moshayedi, Irene L. Llorente, Andrew R. Berg, Jessica Cinkornpumin, William E. Lowry, Tatiana Segura, S. Thomas Carmichael This article presents data related to the research article “Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain” (P. Moshayedi, L.R. Nih, I.L. Llorente, A.R. Berg, J. Cinkornpumin, W.E. Lowry et al., 2016) [1] and focuses on the biocompatibility aspects of the hydrogel, including its stiffness and the inflammatory response of the transplanted organ. We have developed an injectable hyaluronic acid (HA)-based hydrogel for stem cell culture and transplantation, to promote brain tissue repair after stroke. This 3D biomaterial was engineered to bind bioactive signals such as adhesive motifs, as well as releasing growth factors while supporting cell growth and tissue infiltration. We used a Design of Experiment approach to create a complex matrix environment in vitro by keeping the hydrogel platform and cell type constant across conditions while systematically varying peptide motifs and growth factors. The optimized HA hydrogel promoted survival of encapsulated human induced pluripotent stem cell derived-neural progenitor cells (iPS-NPCs) after transplantation into the stroke cavity and differentially tuned transplanted cell fate through the promotion of glial, neuronal or immature/progenitor states. The highlights of this article include: (1) Data of cell and bioactive signals addition on the hydrogel mechanical properties and growth factor diffusion, (2) the use of a design of Experiment (DOE) approach (M.W. 2 Weible and T. Chan-Ling, 2007) [2] to select multi-factorial experimental conditions, and (3) Inflammatory response and cell survival after transplantation.

Description: Publication date: Available online 7 December 2016 Source: Data in Brief Author(s): Akhilesh Kumar Pal, Vimal Katiyar The theoretical and analyzed data incorporated in this article are related to the recently published research article entitled “Thermal degradation behaviour of nanoamphiphilic chitosan dispersed poly (lactic acid) bionanocomposite films” ( http://dx.doi.org/10.1016/j.ijbiomac.2016.11.024 ) (A.K. Pal, V. Katiyar, 2016) [1] . S upplementary information and data (both raw and analyzed) are related to thermal degradation kinetics and explains various model fitting and is conversional methods, which are used in this research work to enhance the knowledge about degradation behaviour of PLA/CH- g -OLLA bionanocomposite system. Non-isothermal degradation kinetics of such polymeric system was proposed using Kissinger, Kissinger–Akahira–Sunose, Flynn–Wall–Ozawa and Augis and Bennett models to estimate the activation energies ( E a ) and R 2 values.

Description: Publication date: Available online 9 December 2016 Source: Data in Brief Author(s): J. Cieślak, J. Tobola The article contains computational data of electronic structure and crystal stability of two sigma-phases, namely Fe-Cr-Co and Fe-Cr-Ni, using the Korringa-Kohn-Rostoker method (KKR) for electronic band structure calculations. Total energy values, E T , calculated for the number of ordered unit cells with various atomic concentrations and sublattice occupancies are reported. In parallel, obtained data are modelled assuming polynomial dependence of the E T -values versus sublattice occupancies. For more details, please see the article “Site occupancies in sigma-phase Fe–Cr–X (X = Co, Ni) alloys: Calculations versus experiment” [1].

Description: Publication date: Available online 9 December 2016 Source: Data in Brief Author(s): Tetsuya Okuda Protein modification by O -linked N -acetylglucosamine ( O -GlcNAcylation) is one of the post transcriptional modifications occurring on cellular proteins. This article provides a data set relating to the O -GlcNAcylation of cellular proteins detected by RL2 and CTD110.6 antibodies, which are commonly used for detection of protein O -GlcNAcylation, in 2-deoxy-D-glucose (2DG)-treated human teratocarcinoma NCCIT cells in support of the research article entitled “A novel, promoter-based, target-specific assay identifies 2-deoxy-D-glucose as an inhibitor of globotriaosylceramide biosynthesis” [1]. The main article described a suppressive effect of 2DG on an Sp1 target gene in NCCIT cells and discussed the relationship between the effect of 2DG and O -GlcNAcylation status of Sp1. The data in this article complements this relationship by Western blotting and clearly showed that the 2DG treatment increased O -GlcNAcylation of cellular proteins in NCCIT cells, whereas the RL2 and CTD110.6 epitopes were detected in a different manner. The RL2 epitope was detected on Sp1 during 2DG treatment, and the level was transiently increased at 24 hours. In contrast, the CTD110.6 epitope became detectable on Sp1 over 72 hours after 2DG treatment, and then the other proteins containing CTD110.6 epitopes also appeared in the cell lysates and the anti-Sp1 antibody precipitates.

Description: Publication date: Available online 9 December 2016 Source: Data in Brief Author(s): B.L. Ennis, E. Jimenez-Melero, R. Mostert, B. Santillana, P.D. Lee In this article we present a new polynomial function for calculating the local phase transformation temperature ( Ae 3 ) between the austenite + ferrite and the fully austenitic phase fields during heating and cooling of steel: A e 3 ( ° C ) = c 0 + ∑ X , k c X k X k + ∑ X , Y , k , m c X k Y m X k Y m + ∑ X , Y , Z , k , m , n c X k Y m Z n X k Y m Z n The dataset includes the terms of the function and the values for the polynomial coefficients for major alloying elements in steel. A short description of the approximation method used to derive and validate the coefficients has also been included. For discussion and application of this model, please refer to the full length article entitled “The role of aluminium in chemical and phase segregation in a TRIP-assisted dual phase steel” doi:10.1016/j.actamat.2016.05.046 [1].

Description: Publication date: Available online 8 December 2016 Source: Data in Brief Author(s): Paul G. Thomes, Elizabeth Brandon-Warner, Ting Li, Terrence M. Donohue, Laura W. Schrum Our data describe autophagic flux in primary rat hepatic stellate cells (rHSCs) treated with pro-fibrotic growth factor, transforming growth factor beta (TGF-β). An autophagy flux experiment determines the rate of synthesis and degradation of the autophagosome marker, LC3-II in the presence and absence of the lysosomal inhibitor bafilomcyin, which blocks LC3-II degradation in lysosomes. The effects of a test agent on LC3-II flux through the autophagic pathway is determined immunochemically by its relative amounts detected in lysates of cells treated with and without bafilomycin. This measurement helps to validate whether exposure to an agent affects the biogenesis or the degradation of autophagosomes during autophagy, a major macromolecular degrading mechanism in eukaryotic cells. (“Rev-erb Agonist and TGF-β Similarly Affect Autophagy but Differentially Regulate Hepatic Stellate Cell Fibrogenic Phenotype” (Thomes et al., in press) [1] .

Description: Publication date: Available online 8 December 2016 Source: Data in Brief Author(s): Andrew A. Kelso, Steven D. Goodson, Lesly A. Temesvari, Michael G. Sehorn This article contains data related to the research article titled “Characterization of the recombination activities of the Entamoeba histolytica Rad51 recombinase” (Kelso et al. , 2016) [1]. The known and putative amino acid sequence of Rad51, the central enzyme of homologous recombination, from nineteen different higher and lower eukaryotic organisms was analyzed. Here, we show amino acid conservation using a multiple sequence alignment, overall sequence identities using a percent identity matrix, and the evolutionary relationship between organisms using a neighbor-joining tree.

Description: Publication date: Available online 8 December 2016 Source: Data in Brief Author(s): Jaymin J. Kathiriya, Ravi Ramesh Pathak, Alexandr Bezginov, Bin Xue, Vladimir N. Uversky, Elisabeth R.M. Tillier, Vrushank Davé We present data on the evolution of intrinsically disordered regions (IDRs) taking into account the entire human protein kinome. The evolutionary data of the IDRs with respect to the kinase domains (KDs) and kinases as a whole protein (WP) are reported. Further, we have reported its post translational modifications of FAK1 IDRs and their contribution to the cytoskeletal remodeling. We also report the data to build a protein-protein interaction (PPI) network of primary and secondary FAK1-interacting hybrid proteins. Detailed analysis of the data and its effect on FAK1-related functions have been described in “Structural pliability adjacent to the kinase domain highlights contribution of FAK1 IDRs to cytoskeletal remodeling” (Kathiriya et. al., 2016) [ 1 ].

Description: Publication date: Available online 8 December 2016 Source: Data in Brief Author(s): Daria Matyushkina, Olga Pobeguts, Irina Garanina, Vladislav Babenko, Maria Vakhitova, Gleb Fisunov, Vadim Govorun The genus Mycoplasma relates to Gram-positive bacteria that lack a cell wall and are capable to cause chronic disease in humans and animals. Among the agents of infection and disease in domestic poultry and wild birds, Mycoplasma gallisepticum is the most important mycoplasma species, causing considerable losses in the poultry industry. In the present paper, we provide data on adaptation of M. gallisepticum to the eukaryotic host cells on the genomic level. The major changes were predominantly localized in the VlhA-hemagglutinin genes which are important components of pathogenesis. The ability of mycoplasmas to change dramatically the repertoire of surface antigens and to vary the immunogenicity of these components allows them to remain undetected by the immune system of the host. The data presented in this article are related to the article entitled “Phase Transition of the Bacterium upon Invasion of a Host Cell as a Mechanism of Adaptation: a Mycoplasma gallisepticum Model.” (Matyushkina et al., 2016) [1] . Data posted in repository https://www.ncbi.nlm.nih.gov/bioproject/315515 . Bioproject ID: PRJNA315515.

Description: Publication date: Available online 13 December 2016 Source: Data in Brief Author(s): Lena Björkman, Huamei Forsman, Karin Önnheim Neutrophils are the key players in inflammatory reactions and the release of superoxide through the NADPH-oxidase upon neutrophil activation contributes to bacterial clearance and surrounding tissue damage. Here we describe data on the mouse neutrophil NADPH-oxidase activation induced by the mouse formyl peptide receptor (Fpr) agonist WKYMVm and galectin-3. Neutrophils isolated from bone marrow, peritoneal exudated, and in vitro TNFα primed bone marrow neutrophils from four different laboratory strains (C57BL/6, DBA/1, BALB/c and NMRI) were used. Both Fpr agonist and galectin-3 activated neutrophils to release superoxide. No differences were observed in the amounts of superoxide released from neutrophils derived from four different strains.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Christelle Haziza, Guillaume de La Bourdonnaye, Dimitra Skiada, Jacek Ancerewicz, Gizelle Baker, Patrick Picavet, Frank Lüdicke Levels of biomarkers of exposure to selected harmful and potentially harmful smoke constituents found in cigarette smoke, in addition to nicotine were measured in 160 smokers randomized for 5 days to continuing smoking conventional cigarettes (41 participants), switching to Tobacco Heating System 2.2 (THS 2.2) (80 participants), or abstaining from smoking (39 participants). The data reported here are descriptive statistics of the levels of each biomarker of exposure expressed as concentrations adjusted to creatinine; at baseline, and at the end of the study, and their relative change from baseline. Reductions in the levels of biomarkers of exposure when expressed as quantity excreted, are also reported. Detailed descriptions of bioanalytical assays used are also provided. The data presented here are related to the article entitled “Evaluation of the Tobacco Heating System 2.2. Part 8: 5-Day randomized reduced exposure clinical study in Poland” (Haziza et al., 2016) [1] .

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Jacqueline F. Aitken, Kerry M. Loomes, Isabel Riba-Garcia, Richard D. Unwin, Gordana Prijic, Ashley S. Phillips, Anthony R.J. Phillips, Donghai Wu, Sally D. Poppitt, Ke Ding, Perdita E. Barran, Andrew W. Dowsey, Garth J.S. Cooper Here we provide data describing the time-course of blood-glucose and fluid-intake profiles of diabetic hemizygous human-amylin (hA) transgenic mice orally treated with rutin, and matched control mice treated with water. We employed “parametric change-point regression analysis” for investigation of differences in time-course profiles between the control and rutin-treatment groups to extract, for each animal, baseline levels of blood glucose and fluid-intake, the change-point time at which blood glucose (diabetes-onset) and fluid-intake (polydipsia-onset) accelerated away from baseline, and the rate of this acceleration. The parametric change-point regression approach applied here allowed a much more accurate determination of the exact time of onset of diabetes than do the standard diagnostic criteria. These data are related to the article entitled “Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro , and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice” (J.F. Aitken, K.M. Loomes, I. Riba-Garcia, R.D. Unwin, G. Prijic, A.S. Phillips, A.R.J. Phillips, D. Wu, S.D. Poppitt, K. Ding, P.E. Barran, A.W. Dowsey, G.J.S. Cooper. 2016) [1] .

Description: Publication date: Available online 13 December 2016 Source: Data in Brief Author(s): Alexandra M. Hetherington, Cynthia G. Sawyez, Nica M. Borradaile As nonalcoholic fatty liver disease progresses to end-stage diseases, including fibrosis, cirrhosis and hepatocellular carcinoma, fibrotic activated hepatic stellate cells and cancerous epithelial cells can become abundant, changing the cellular composition of this organ. Despite potentially residing within the same diseased tissue, direct comparisons of global gene expression between activated hepatic stellate cells and hepatocellular carcinoma cells are lacking. Here we provide data collected using Affymetrix GeneChip microarrays to identify differential gene expression in cultured primary human activated hepatic stellate cells compared to HepG2 human hepatoma cells. The dataset includes many genes involved in intermediary metabolism which were investigated in greater depth in our associated article [1]. Pathway analyses of known protein coding genes down-regulated or up-regulated by greater than 2.0-fold are also provided.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): A.S. Nikitina, E.I. Sharova, S.A. Danilenko, O.V. Selezneva, T.B. Butusova, A.O. Vasiliev, A.V. Govorov, E.A. Prilepskaya, D.Y. Pushkar, E.S. Kostryukova Current prostate cancer (PCa) diagnostic tests suffer from insufficient sensitivity and specificity. Novel biomarkers that can be detected by minimally invasive methods are of a particular value. Here we provide two datasets. The first one is on the whole transcriptome profiling by RNA-seq of urine and plasma obtained from patients with PCa and benign prostatic hyperplasia (BPH). The second one represents targeted sequencing of DNA from urine and plasma of patients with PCa and BPH. Both datasets are available at NCBI Sequence Read Archive under Accession No. SRP093707 and No. SRP093842 respectively.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Hideko T. Oyama, Daisuke Tanishima, Shintaro Maekawa This article reports experimental data related to the research article entitled “Poly(malic acid-co- l -lactide) as a Superb Degradation Accelerator for Poly( l -lactic acid) at Physiological Conditions” (H.T. Oyama, D. Tanishima, S. Maekawa, 2016) [1] . Hydrolytic degradation of poly( l -lactic acid) (PLLA) blends with poly(aspartic acid-co- l -lactide) (PAL) and poly(malic acid-co- l -lactide) (PML) oligomers was investigated in a phosphate buffer solution at 40 °C. It was found in the differential scanning calorimetry measurements that upon hydrolysis the cold crystallization temperature ( T c ) and the melting temperature ( T m ) significantly shifted to lower temperature. Furthermore, the hydrolysis significantly promoted water sorption in both blends.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Ahmed A.A. Khalifa, Pietro Bertuccelli, Edoardo Otranto This article includes a unique data set of a balanced daily (Monday, Tuesday and Wednesday) for oil and natural gas volatility and the oil rich economies’ stock markets for Saudi Arabia, Qatar, Kuwait, Abu Dhabi, Dubai, Bahrain and Oman, using daily data over the period spanning Oct. 18, 2006–July 30, 2015. Additionally, we have included unique GAUSS codes for estimating the spillover asymmetric multiplicative error model (SAMEM) with application to Petroleum-Based Stock Market. The data, the model and the codes have many applications in business and social science.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Xue-Juan Li, Li-Liang Lin, Ai-Ming Cui, Jie Bai, Xiao-Yang Wang, Chao Xin, Zhen Zhang, Chao Yang, Rui-Rui Gao, Yuan Huang, Fu-Min Lei The data in this paper are related to the research article entitled “Taxonomic status and phylogenetic relationship of tits based on mitogenomes and nuclear segments” (X.J. Li et al., 2016) [1] . The mitochondrial genomes and nuclear segments of tits were sequenced to analyze mitochondrial characteristics and phylogeny. In the data, the analyzed results are presented. The data holds the resulting files of mitochondrial characteristics, heterogeneity, best schemes, and trees.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Kenneth E. Strawhecker, Emil J. Sandoz-Rosado, Taylor A. Stockdale, Eric D. Laird The data included here provides a basis for understanding “Interior morphology of high-performance polyethylene fibers revealed by modulus mapping” (K.E. Strawhecker, E.J. Sandoz-Rosado, T.A. Stockdale, E.D. Laird, 2016) [1] , in specific: the multi-frequency (AMFM) atomic force microscopy technique and its application to ultra-high-molecular-weight Polyethylene (UHMWPE) fibers. Furthermore, the data suggests why the Hertzian contact mechanics model can be used within the framework of AMFM theory, simple harmonic oscillator theory, and contact mechanics. The framework is first laid out followed by data showing cantilever dynamics, force-distance spectra in AC mode, and force-distance in contact mode using Polystyrene reference and UHMWPE. Finally topography and frequency shift (stiffness) maps are presented to show the cases where elastic versus plastic deformation may have occurred.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Ragini Khajuria, Rama Walia, Anil Bhansali, Rajendra Prasad This article presents the dataset regarding spectrum of mutations in 21-Hydroxylase deficient CAH patients as described in “The spectrum of CYP21A2 mutations in Congenital Adrenal Hyperplasia in an Indian cohort” (R. Khajuria, R. Walia, A. Bhansali, R. Prasad, 2017) [1] . This dataset features about the CAH patients in the cohort, their classification into subtypes and finally screening the exon–intron boundaries of 21-Hydroxylase gene (CYP21A2) to detect common mutations, novel mutations along polymorphisms in the CYP21A2 gene. The specified large set of primers and the parameters for the mutation detection allow the identification and molecular characterization of CYP21A2 gene in the CAH patients.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Abul Kalam, Sushama Talegaonkar, Divya Vohora Currently, the third generation aromatase inhibitors are the drugs of choice for treatment of early and advanced breast cancer in postmenopausal women. The negative impact of these drugs on bone health is the significant limiting factor during this therapy. Here we report the effect of two aromatase inhibitors viz. letrozole and exemestane alone and in combination with raloxifene on lumbar vertebrae and femoral diaphysis after one month of treatment but no discernible effects were observed on bone when tested by micro CT and strength test except in trabecular number which was reduced in lumbar vertebrae following letrozole and exemestane. Further studies with letrozole and exemestane should be done at higher doses for longer duration of time to check whether effects are observed in other parameters as well. The data is an extension of our published work in Mol. Cell Endocrinology (A. Kalam, S. Talegaonkar, D. Vohora, 2017) [1] describing letrozole-induced bone loss on femoral epiphysis and its reversal by raloxifene.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Israel Estrada-Contreras, César A. Sandoval-Ruiz, Fredy S. Mendoza-Palmero, Sergio Ibáñez-Bernal, Miguel Equihua, Griselda Benítez The data presented in this article are related to the research article entitled “Establishment of Aedes aegypti (L.) in mountainous regions in Mexico: Increasing number of population at risk of mosquito-borne disease and future climate conditions” (M. Equihua, S. Ibáñez-Bernal, G. Benítez, I. Estrada-Contreras, C.A. Sandoval-Ruiz, F.S. Mendoza-Palmero, 2016) [1] . This article provides presence records in shapefile format used to generate maps of potential distribution of Aedes aegypti with different climate change scenarios as well as each of the maps obtained in raster format. In addition, tables with values of potential distribution of the vector as well as the average values of probability of presence including data of the mosquito incidence along the altitudinal range.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Hao Wang, Xuming Sun, Jeff Chou, Marina Lin, Carlos M. Ferrario, Gisele Zapata-Sudo, Leanne Groban We previously showed that cardiomyocyte-specific G protein-coupled estrogen receptor (GPER) gene deletion leads to sex-specific adverse effects on cardiac structure and function; alterations which may be due to distinct differences in mitochondrial and inflammatory processes between sexes. Here, we provide the results of Gene Set Enrichment Analysis (GSEA) based on the DNA microarray data from GPER-knockout versus GPER-intact (intact) cardiomyocytes. This article contains complete data on the mitochondrial and inflammatory response-related gene expression changes that were significant in GPER knockout versus intact cardiomyocytes from adult male and female mice. The data are supplemental to our original research article “Cardiomyocyte-specific deletion of the G protein-coupled estrogen receptor (GPER) leads to left ventricular dysfunction and adverse remodeling: a sex-specific gene profiling” (Wang et al., 2016) [1] . Data have been deposited to the Gene Expression Omnibus (GEO) database repository with the dataset identifier GSE86843 .

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Liangliang Zhang, Indra Dev Sahu, Man Xu, Yongmei Wang, Xinyu Hu This data article contains complementary results related to the paper “Effect of metal ions on the binding reaction of (-)-epigallocatechin gallate to β -lactoglobulin” (Zhang et al., 2017) [1] . Data was obtained by circular dichroism (CD) spectroscopy to investigate potential β -lactoglobulin ( β -Lg) conformational changes with different concentrations of EGCg and Cu 2+ or Al 3+ added to β -Lg. 500 µL of the 25 µM β -Lg solution containing EGCg (25 µM) or metal ions (0–500 µM) were measured, and the spectra were recorded. CD spectroscopy data present in this article indicated that the β -Lg-Cu, β -Lg-Al and β -Lg-EGCg interaction resulted in unfolding of the secondary structure of β -Lg.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Eleanor D. Muise, Neeru Gandotra, John J. Tackett, Michaela C. Bamdad, Robert A. Cowles The data presented in this article are related to the research article entitled “Distribution of muscarinic acetylcholine receptor subtypes in the murine small intestine” (E.D. Muise, N. Gandotra, J.J. Tackett, M.C. Bamdad, R.A. Cowles, 2016) [1] . We recently demonstrated that neuronal serotonin stimulates intestinal crypt cell division, and induces villus growth and crypt depth (E.R. Gross, M.D. Gershon, K.G. Margolis, Z.V. Gertsberg, Z. Li, R.A. Cowles, 2012; M.D. Gershon, 2013) [2,3] . Scopolamine, a nonspecific muscarinic receptor antagonist, inhibited serotonin-induced intestinal mucosal growth [2] . Here we provide data regarding the localization of muscarinic acetylcholine receptor 2 to the intestinal crypt stem cell compartment.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Zhuo-Xiao Han, Mohammad M. Rana, Guo-Feng Liu, Ming-Jun Gao, Da-Xiang Li, Fu-Guang Wu, Xin-Bao Li, Xiao-Chun Wan, Shu Wei This paper presents data related to an article entitled “Green tea flavor determinants and their changes over manufacturing processes” (Han et al., 2016) [1]. Green tea samples were prepared with steaming and pan firing treatments from the tender leaves of tea cultivars ‘Bai-Sang Cha’ (‘BAS’) and ‘Fuding-Dabai Cha’ (‘FUD’). Aroma compounds from the tea infusions were detected and quantified using HS-SPME coupled with GC/MS. Sensory evaluation was also made for characteristic tea flavor. The data shows the abundances of the detected aroma compounds, their threshold values and odor characteristics in the two differently processed tea samples as well as two different cultivars.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Jinsoo Yi, Tine A. Knudsen, Anne-Louise Nielsen, Lars Duelund, Morten Christensen, Pablo Hervella, David Needham, Ole G. Mouritsen The data in this paper are additional information to the research article entiltled “Inhibition of cholesterol transport in an intestine cell model by pine-derived phytosterols” (Yi et al.,2016) [1] . The data derived from the measurement on six liquid formulations of commercial pine-derived phytosterol (CPP) by dynamic light scattering. The data cover micelle size and the zeta-potential for formulations with cholesterol including monoglyceride, oleic acid, and bile salt. The data demonstrate the critical effect of the bile salt concentration on the size of cholesterol-digested fat micelles.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Pinru Wu, Gang Ma, Ningli Li The data presented in this article are related to the research article entitled “Cyr61/CCN1 is involved in the pathogenesis of psoriasis vulgaris via promoting IL-8 production by keratinocytes in a JNK/NF-κB pathway” (Pinru Wu, Gang Ma, Xianjin Zhu, Ting Gu, Jie Zhang, Yue Sun, Hui Xu, Rongfen Huo, Beiqing Wang, Baihua Shen, Xiangdong Chen, Ningli Li, 2016) [1] . Cysteine-rich 61 (Cyr61/CCN1), a secreted extracellular matrix protein, is a novel proinflammatory factor. In this dataset skin samples from normal donors and psoriasis vulgaris patients were examined the expression of Cyr61 and IL-8 using immunohistochemistry. IMQ-induced psoriasis-like mice were treated with anti-Cyr61monoclonal antibodies (mAb).

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Odd André Hjelkrem, Eirin Olaussen Ryeng In this data set, vehicle observations have been linked to data containing weather and road surface conditions. A total of 311 908 observations are collected and classified in categories of precipitation type, road status information, and daylight condition. The data is collected for a long period of time, so that several different weather situations are present, ranging from dry summer to adverse winter weather conditions.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Selene Baos, David Calzada, Lucía Cremades, Joaquín Sastre, Joaquín Quiralte, Fernando Florido, Carlos Lahoz, Blanca Cárdaba This article contains information related to the research article entitled “Biomarkers associated with disease severity in allergic and nonallergic asthma” (S. Baos, D. Calzada, L. Cremades, J. Sastre, J. Quiralte, F. Florido, C. Lahoz, B. Cárdaba, In press). Specifically, the clinical criteria stablished for selecting the study population ( n =104 subjects) are described. Moreover, this article describes the criteria for selecting the 94 genes to be analyzed in PBMCs (peripheral blood mononuclear cells), it is provided a description of these genes and a Table with the genes most differentially expressed by clinical phenotypes and, finally it is detailed the experimental methodology followed for studying the protein expression of MSR1 (macrophage scavenger receptor 1), one of the genes evaluated in the research.

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Stefan Vögele, Patrick Hansen, Witold-Roger Poganietz, Sigrid Prehofer, Wolfgang Weimer-Jehle Many studies stress the needs of interdependence analysis under the special conditions of multidisciplinary systems that include social systems. This applies, in particular, to scenarios on future energy demand and supply. Using the example of the residential sector in Germany we provide information on factors and their possible outcomes taking multidisciplinary aspects into account. In addition, futures are presented reflecting consistent combinations of the outcomes of the selected factors. These futures can be used as storylines for further analyses (see (S. Vögele, P. Hansen, W-R. Poganietz, S. Prehofer, W. Weimer-Jehle) [1] ).

Description: Publication date: February 2017 Source: Data in Brief, Volume 10 Author(s): Jiao Yang, Lei Zhou, Qinglian Liu Human BiP/GRP78 is involved in the folding and assembly of proteins in the endoplasmic reticulum. The proteins for crystallization in good amount and quality are prerequisites for obtaining ideal crystals. To meet these requirements, different BiP/GRP78 constructs, competent cells, vectors, and concentrations of inducer were tested in order to obtain soluble BiP/GRP78 protein with the highest amount and best purity. The BiP–T229A–L 3,4′ –Smt3 fusion protein was expressed in a soluble manner and finally purified with the highest purity using size exclusion chromatography, which was suitable for further protein crystallization.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Xu Zhang, Yujie Wang, Duo Yang, Zonghai Chen This article provides the dataset of operating conditions of battery behavior. The constant current condition and the dynamic stress test (DST) condition were carried out to analyze the battery discharging and charging features. The datasets were achieved at room temperature, in April, 2016. The shared data contributes to clarify the battery pack state-of-charge (SOC) and the battery inconsistency, which is also shown in the article of “An on-line estimation of battery pack parameters and state-of-charge using dual filters based on pack model” (X. Zhang, Y. Wang, D. Yang, et al., 2016) [1] .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Cédric Gaillard, Yunhui Wang, Rudy Covis, Thomas Vives, Maud Benoit, Thierry Benvegnu This article contains data on the Laser Scanning Confocal Microscopy (LSCM) and Transmission Electron Microscopy (TEM) images related to multi-scaled self-assemblies resulting from ‘green’ cationic glycine betaine surfactant/anionic kappa-carrageenan interactions. These data gave clear evidence of the evolution of the micron-, nano-sized structures obtained at two surfactant/polymer molar ratios (3.5 and 0.8) and after the dilution of the aqueous dispersions with factors of 5 and 10 times. This data article is related to the research article entitled, “Monitoring the architecture of anionic ĸ-carrageenan/cationic glycine betaine amide surfactant assemblies by dilution: A multiscale approach” (Gaillard et al., 2017) [1] .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Cristina Baglivo, Paolo Maria Congedo Data are related to the multi-objective optimization process applied to the building materials to obtain high energy-efficient precast walls for cold climate. The methodology has been explained on the paper entitled “High performance precast external walls for cold climate by a multi criteria methodology” (Baglivo and Congedo, 2016) [1]. The modeFRONTIER rel.4.3 optimization tool has been used to evaluate the dynamic behaviour of the building components in accordance with the UNI EN ISO 13786:2008 and to obtain a multitude of high efficiency configurations. The results are divided into three categories thick, thin and ultra-thin precast walls, in accordance with their thicknesses. The input data are the building materials with their thermal properties, sustainability characteristics and the supply and installation costs. The output values of the simulations are adapted to the cold climate and based on thermal properties, costs and sustainability score. Several combinations of external precast walls have been shown as optimal for cold climate.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Zheng Fang This article describes two publicly available data sources: the new generation of Penn World Table ( www.ggdc.net/pwt ) and the BP Statistical Review of World Energy ( http://www.bp.com/statisticalreview ) which can be used to examine the role of human capital in the energy-growth nexus across countries. The critical human capital measure across countries is for the first time made available in the Penn World Table 8.0 and it enables empirical researchers to conduct cross-country analysis involving human capital much easily than ever before.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Simone Queiroz da Silveira Hirashima, Eleonora Sad de Assis, Marialena Nikolopoulou This dataset describe microclimatic parameters of two urban open public spaces in the city of Belo Horizonte, Brazil; physiological equivalent temperature (PET) index values and the related subjective responses of interviewees regarding thermal sensation perception and preference and thermal comfort evaluation. Individuals and behavioral characteristics of respondents were also presented. Data were collected at daytime, in summer and winter, 2013. Statistical treatment of this data was firstly presented in a PhD Thesis (“Percepção sonora e térmica e avaliação de conforto em espaços urbanos abertos do município de Belo Horizonte – MG, Brasil” (Hirashima, 2014) [1] ), providing relevant information on thermal conditions in these locations and on thermal comfort assessment. Up to now, this data was also explored in the article “Daytime Thermal Comfort in Urban Spaces: A Field Study in Brazil” (Hirashima et al., in press) [2] . These references are recommended for further interpretation and discussion.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Payam Nejat, John Kaiser Calautit, Muhd Zaimi Abd. Majid, Ben Richard Hughes, Iman Zeynali, Fatemeh Jomehzadeh The data presented in this article were the basis for the study reported in the research articles entitled “Evaluation of a two-sided windcatcher integrated with wing wall (as a new design) and comparison with a conventional windcatcher” (P. Nejat, J.K. Calautit, M.Z.A. Majid, B.R. Hughes, I. Zeynali, F. Jomehzadeh, 2016) [1] which presents the effect of wing wall on the air flow distribution under using the windcatchers as a natural ventilation equipment. Here, we detail the wind tunnel testing and numerical set-up used for obtaining the data on ventilation rates and indoor airflow distribution inside a test room with a two-sided windcatcher and wing wall. Three models were integrated with wing wall angled at 30°, 45° and 60° and another windcatcher was a conventional two-sided device. The computer-aided design (CAD) three-dimensional geometries which were produced using Solid Edge modeler are also included in the data article.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Weiguo Wang, Jing Xue, Chonghua Du This article introduces the data of the log real GDP per capita ratio and the log real exchange rate which are used to revisit the Balassa–Samuelson Hypothesis. We acquired the data from IMF and World Bank database, and provide the name and source of the data. All data are openly accessible. Besides, we describe the value of data as well as the method to process the data which can also be found in “The Balassa–Samuelson Hypothesis in the developed and developing countries revisited” (Weiguo Wang, Jing Xue, Chonghua Du, 2016) [1] .

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): J. Chandramohan, G. Senthilkumar, M. Suresh Gandhi, R. Ravisankar This article contains the chemical and geographical data and figures for the chemical data in sediments of East Coast (Pattipulam to Dhevanampattinam) of Tamilnadu. The obtained data are related to the research article “Heavy Metal Assessment in Sediment Samples Collected From Pattipulam to Dhevanampattinam along the East Coast of Tamil Nadu Using EDXRF Technique” (Chandramohan et al., 2016) [1] . Chemical data are collected from Energy dispersive X-ray fluorescence spectrometer (EDXRF). Furthermore, the obtained chemical data describes it in more detail in the figures.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): John H.R. Burns, Theodore Alexandrov, Katya Ovchinnikova, Ruth D. Gates, Misaki Takabayashi Ten annotated 3D reconstructions of Montipora capitata coral colonies contain x,y,z coordinates for all growth anomaly (GA) lesions affecting these corals. The 3D reconstructions are available as Virtual Reality Modeling Language (VRML) files, and the GA lesions coordinates are in accompanying text files. The VRML models and GA lesion coordinates can be spatially analyzed using Matlab. Matlab scripts are provided for three spatial statistical procedures in order to assess clustering of the GA lesions across the coral colony surfaces in a 3D framework: Ripley׳s K, Moran׳s I, and the Kolmogorov–Smirnov test. Please see the research article, “Investigating the spatial distribution of Growth Anomalies affecting Montipora capitata corals in a 3-dimensional framework” (J.H.R. Burns, T. Alexandrov, E. Ovchinnikova, R.D. Gates, M. Takabayashi, 2016) [1] , for further interpretation and discussion of the data.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Costas A. Anagnostopoulos, Minas Tsiatis The use of additives to improve the quality of cement grouts is crucial for civil engineering, especially in foundation construction. This article presents experimental data concerning the compressive strength, elastic modulus, bleeding and injectability of microfine cement grouts modified with epoxy and acrylic resin emulsions. Strength properties were obtained at different curing ages. For further analysis and detailed discussion of properties of polymer-modified cement grouts, see “Fundamental properties of epoxy resin-modified cement grouts” (C.A. Anagnostopoulos, G. Sapidis, E. Papastergiadis, 2016) [1].

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Maura N. Laus, Mario Soccio, Michela Alfarano, Antonella Pasqualone, Marcello S. Lenucci, Giuseppe Di Miceli, Donato Pastore This article reports experimental data related to the research article entitled “Different effectiveness of two pastas supplemented with either lipophilic or hydrophilic/phenolic antioxidants in affecting serum as evaluated by the novel Antioxidant/Oxidant Balance approach” (M.N. Laus, M. Soccio, M. Alfarano, A. Pasqualone, M.S. Lenucci, G. Di Miceli, D. Pastore, 2016) [1] . Antioxidant status of blood serum of seven healthy subjects was evaluated during four hours after consumption of two functional pastas, supplemented with either bran oleoresin or bran water extract obtained from durum wheat. For comparison, the effect of a non-supplemented reference pasta was also evaluated, as well as the effects of glucose, of the wheat grain dietary supplement Lisosan G, and of the reference pasta consumed together with Lisosan G. Serum antioxidant status was evaluated by measuring both the serum antioxidant capacity, using LOX-FL, ORAC and TEAC methods, and the serum oxidant status, assessed as peroxide level.

Description: Publication date: December 2016 Source: Data in Brief, Volume 9 Author(s): Ilaria Zacà, Giuliano Tornese, Cristina Baglivo, Paolo Maria Congedo, Delia D’Agostino "Efficient Solutions and Cost-Optimal Analysis for Existing School Buildings" (Paolo Maria Congedo, Delia D’Agostino, Cristina Baglivo, Giuliano Tornese, Ilaria Zacà) [1] is the paper that refers to this article. It reports the data related to the establishment of several variants of energy efficient retrofit measures selected for two existing school buildings located in the Mediterranean area. In compliance with the cost-optimal analysis described in the Energy Performance of Buildings Directive and its guidelines (EU, Directive, EU 244,) [2,3] , these data are useful for the integration of renewable energy sources and high performance technical systems for school renovation. The data of cost-efficient high performance solutions are provided in tables that are explained within the following sections. The data focus on the describe school refurbishment sector to which European policies and investments are directed. A methodological approach already used in previous studies about new buildings is followed (Baglivo Cristina, Congedo Paolo Maria, D׳Agostino Delia, Zacà Ilaria, 2015; IlariaZacà, Delia D’Agostino, Paolo Maria Congedo, Cristina Baglivo; Baglivo Cristina, Congedo Paolo Maria, D’Agostino Delia, Zacà Ilaria, 2015; Ilaria Zacà, Delia D’Agostino, Paolo Maria Congedo, Cristina Baglivo, 2015; Paolo Maria Congedo, Cristina Baglivo, IlariaZacà, Delia D’Agostino,2015) [4–8] . The files give the cost-optimal solutions for a kindergarten (REF1) and a nursery (REF2) school located in Sanarica and Squinzano (province of Lecce Southern Italy). The two reference buildings differ for construction period, materials and systems. The eleven tables provided contain data about the localization of the buildings, geometrical features and thermal properties of the envelope, as well as the energy efficiency measures related to walls, windows, heating, cooling, dhw and renewables. Output values of energy consumption, gas emission and costs are given for a financial and a macro-economic analysis. This data article provides 288 and 96 combinations for REF1 and REF2, respectively. The output values are obtained using the software ProCasaClima 2015v.2.0.