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  • 1
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    Chapter 13 The value of the imagined biological in policy and society (2021)
    Taylor & Francis | Routledge
    Details
    Publication Date: 2024-04-07
    Description: Attending the World Economic Forum this past week, I was struck by two trends. The first was that brain research has emerged as a hot topic. Not only was brain science or brain health a new theme at the meeting, research on the brain emerged in discussions about next generation computing, global cooperation, and even models of economic development as well as being linked to mental health or mindfulness. In a meeting frequented largely by economists and business leaders, I was surprised by the number of non-scientists who have become enchanted by brain science. Clearly this is the era of the brain, with mental health now part of a much broader discussion.
    Keywords: policy ; society ; mental health ; Biology ; Epigenetics ; Genetics ; Genome ; Neuroscience ; Plastic ; Social policy ; thema EDItEUR::J Society and Social Sciences ; thema EDItEUR::M Medicine and Nursing
    Language: English
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  • 2
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    Statistical Population Genomics (2021)
    Springer Nature
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    Publication Date: 2024-04-06
    Description: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions.
    Keywords: Life sciences ; Bioinformatics ; Genetics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
    Language: English
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  • 3
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    Neuroscience of Human Attachment (2021)
    Frontiers Media SA
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    Publication Date: 2024-04-05
    Description: Attachment is a biologically emotion regulation based system guiding cognitive and emotional processes with respect to intimate and significant relationships. Secure relationships promote infants’ exploration of the world and expand their mastery of the environment. Adverse attachment experiences like, maltreatment, loss, and separation have long been known to have enduring unfavorable effects on human mental health. Research on the neurobiological basis of attachment started with animal studies focusing on emotional deprivation and its behavioral, molecular and endocrine consequences. The present book presents an interdisciplinary synthesis of existing knowledge and new perspectives on the human neuroscience of attachment, showing the tremendous development of this field. The following chapters include innovative studies that are representative of the broad spectrum of current approaches. These involve both differing neurobiological types of substrates using measures like fMRI, EEG, psychophysiology, endocrine parameters, and genetic polymorphisms, as well as psychometric approaches to classify attachment patterns in individuals. The findings we have acquired in the meanwhile on the neural substrates of attachment in healthy subjects lay the foundation of studies with clinical groups. The final section of the book addresses evidence on changes in the functioning of these neural substrates in psychopathology.
    Keywords: RC321-571 ; Q1-390 ; fMRI ; Neuroscience ; social cognition ; Brain activity ; EEG ; Genetics ; Attachment ; Attachment representation ; Psychopathology ; Neurophysiology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 4
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    Equine Science (2024)
    IntechOpen | IntechOpen
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    Publication Date: 2024-04-05
    Description: Equine Science - Applications and Implications of New Technologies explores the fascinating world of history and technological advances in equine research. This comprehensive book explores the history and health of horses and the use of reproductive technologies in these animals. As tradition meets innovation, it delves into the ethical implications and responsible use of these technologies to ensure animal welfare. Expertly authored by scientists, it is an indispensable guide for horse enthusiasts, veterinarians, trainers, and researchers seeking to harness the power of innovation to unlock the full potential of the equine species.
    Keywords: Clinical and Laboratory Diagnosis ; System Disorders ; Genetics ; Biochemistry ; Exercise ; Anatomy ; Physiology ; Biomechanics ; Reproduction ; Artificial Insemination ; Embryo ; Hormones ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSV Zoology and animal sciences
    Language: English
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  • 5
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    Human and Animal Models for Translational Research on Neurodegeneration: Challenges and Opportunities From South America (2021)
    Frontiers Media SA
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    Publication Date: 2024-04-05
    Description: Neurodegenerative diseases are the most frequent cause of dementia, representing a burden for public health systems (especially in middle and middle-high income countries). Although most research on this issue is concentrated in first-world centers, growing efforts in South America are affording important breakthroughs. This emerging agenda poses new challenges for the region but also new opportunities for the field. This book aims to integrate the community of experts across the globe and the region, and to establish new challenges and developments for future investigation. We present research focused on neurodegenerative research in South America. We introduce studies assessing the interplay among genetic, neural, and behavioral dimensions of these diseases, as well as articles on vulnerability factors, comparisons of findings from various countries, and works promoting multicenter and collaborative networking. More generally, our book covers a broad scope of human-research approaches (behavioral assessment, neuroimaging, electromagnetic techniques, brain connectivity, peripheral measures), animal methodologies (genetics, epigenetics, proteomics, metabolomics, other molecular biology tools), species (all human and non-human animals, sporadic, and genetic versions), and article types (original research, review, and opinion papers). Through this wide-ranging proposal, we hope to introduce a fresh approach to the challenges and opportunities of research on neurodegeneration in South America.
    Keywords: RC321-571 ; Q1-390 ; South America ; Multicenter research ; Neurodegenerative Diseases ; Neurosciences ; Public Health ; Animals ; Clinical Protocols ; Research ; Human Experimentation ; Dementia ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 6
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    Improving Animal Welfare through Genetic Selection (2021)
    Frontiers Media SA
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    Publication Date: 2024-04-05
    Description: In livestock species, breeding goals are aimed primarily at improvement of production traits. However, there are a number of examples where selection for high production efficiency has resulted in reduced welfare through unfavorable outcomes in health and fitness characteristics. These effects raise questions about what is ethically acceptable in animal breeding. Welfare problems may be experienced when physiological balance is disturbed by genetic selection for high production alone, by a mismatch between the environmental challenges and the range of coping responses available to an animal, or from a mismatch between the animal’s needs and their degree of satisfaction. This may be resolved by either improving the environment to support the animal, but also by providing the animal, through genetic selection, with means to adapt to the production environment. The Standing Committee of the European Convention for the Protection of Animals kept for Farming Purposes emphasizes that breeding goals should include health and welfare. The Farm Animal Welfare Council pleas for a greater emphasis in breeding programs on traits associated with good welfare. However, although breeding goals in most farm animal species have been broadened beyond production traits to include functional traits, behavioral traits are rarely included despite their potential to improve animal production and welfare. It is the goal of the present Research Topic to bring together experimental and theoretical research focusing on the genetics of welfare traits and the possibility to improve animal welfare through selection. This topic presents an overview of the relationship between selection for high production and livestock robustness, examples of improving robustness through the introduction of novel traits in livestock breeding, and a discussion on selection methods to address welfare issues. The discussion on sustainability of breeding practices is very alive today and will remain to be an important part of the debate in the future.
    Keywords: QH426-470 ; Q1-390 ; animal breeding ; livestock improvement ; selection ; livestock production ; Genetics ; welfare ; sustainable agriculture ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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  • 7
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    Society, Organizations and the Brain: building towards a unified cognitive neuroscience perspective (2021)
    Frontiers Media SA
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    Publication Date: 2024-04-05
    Description: This e-book brings together scholars in both the neurosciences and organizational sciences who have adopted various approaches to study the cognitive mechanisms mediating the social behavior that we see within organizations. Such an approach has been termed by ourselves, and others, as ‘organisational cognitive neuroscience’. In recent years there has been a veritable increase in studies that have explored the cognitive mechanisms driving such behaviors, and much progress has been made in understanding the neural underpinnings of processes such as financial exchange, risk awareness and even leadership. However, while these studies are informative and add to our understanding of human cognition they fall short of providing evidence-based recommendations for practice. Specifically, we address the broader issue of how the neuroscientific study of such core social behaviors can be used to improve the very way that we work. To address these gaps in our understanding the chapters in this book serve as a platform that allows scholars in both the neurosciences and the organizational sciences to highlight the work that spans across these two fields. The consolidation of these two fields also serves to highlight the utility of a singular organizational cognitive neuroscience. This is a fundamentally important outcome of the book as the application of neuroscience to address economically relevant behaviors has seen a variety of fields evolve in their own right, such as neuromarketing, neuroeconomics and so forth. The use of neuro-scientific technologies,in particular fMRI, has indeed led to a bewildering (and somewhat suffocating) proliferation of new approaches, however, the speed of such developments demands that we must proceed carefully with such ventures or risk some fundamental mistakes. The book that you now hold will consolidates these new neuroscience based approaches and in doing so highlight the importance of this approach in helping us to understand human social behavior in general. Taken together the chapters provide a framework for scholars within the neurosciences who wish to explore the further the opportunities that the study of organisational behavior may provide.
    Keywords: RC321-571 ; Q1-390 ; Brain ; Neuroscience ; organisations ; Functional Brain imaging ; Genetics ; neuroeconomics ; neuromarketing ; MEG ; Organisational Cognitive Neuroscience society ; Marketing ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAN Neurosciences
    Language: English
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  • 8
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    Papers of the Conference on Genetics of Aging and Longevity 2012 (2021)
    Frontiers Media SA
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    Publication Date: 2024-04-05
    Description: The 2nd International Conference "Genetics of aging and longevity" took place 22-25 April, 2012 in the main building of Russian Academy of Sciences, Moscow, Russia. Top gerontologists and geneticists from 25 countries around the world discussed the current problems in many areas related to the genetics of longevity and mechanisms of aging. This Research Topic is aimed to provide a collection of articles based on the talks, reports and experimental outcomes related to the topics of the conference: "Epigenetic Changes Associated with Longevity", "Hormones and Aging", "Proximal and Cellular Mechanisms of Aging", "Nutrient Signaling, Stress Resistance and Longevity", "Identifying Longevity Genes by Mutational, QTL and Association Mapping", "Fundamental Biological Processes Central to Aging", "Interventions to Extend Lifespan and Promote Healthy Aging", "Longevity: Meta-Analysis and Informatics Approaches". Participants of the Conference submitted 20 papers belonging to Original Research Papers, Review Articles (Including Mini Reviews), Opinion and Perspective Papers. All of the submitted manuscripts were peer-reviewed by excellent Frontiers Review Editors and prepared for publication by highly efficient Frontiers team, and it is a pleasure to thank them all for their work and dedication.
    Keywords: QH426-470 ; Q1-390 ; Aging ; Genetics ; geroprotectors ; evolution ; epigenetics ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)
    Language: English
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  • 9
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    Surveying Antimicrobial Resistance: Approaches, Issues, and Challenges to Overcome (2021)
    Frontiers Media SA
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    Publication Date: 2024-04-05
    Description: Why Antibiotic Resistance? The use of antibiotics in human and veterinary medicine may have consequences beyond their intended applications. The “One Health” concept recognizes that the health of humans is connected to the health of animals and the environment. Progress in molecular genetics is facilitating the rapid evaluation of the essentiality of these targets on a genomic scale. In 2015, a group of researchers established the International Conference on Antibiotic Resistance (IC2AR).The primary objective of this meeting is to bring together scientists involved in antibiotic resistance prevention and control. The IC2AR conducted its inaugural world congress in January 2015 at Caparica (Portugal). Antimicrobial resistance presents a significant challenge to scientists in the field of infectious diseases. The full knowledge of how antibiotics resistance is evolving and being transmitted between hosts in different ecosystems is taking on great importance. Necessary action includes research to define the scope of the problem including its various sources. This eBook comprises a series of original research and review articles dealing with the epidemiology of resistance in animal and zoonotic pathogens, mobile elements containing resistance genes, the omics of antimicrobial resistance, emerging antimicrobial resistance mechanisms, control of resistant infections, establishing antimicrobial use and resistance surveillance systems, and alternatives strategies to overcome the problem of antimicrobial resistance worldwide. Gilberto Igrejas, José Luis Capelo and Patrícia Poeta Scientific Committee of IC2AR, February 20th, 2017Why Antibiotic Resistance? The use of antibiotics in human and veterinary medicine may have consequences beyond their intended applications. The “One Health” concept recognizes that the health of humans is connected to the health of animals and the environment. Progress in molecular genetics is facilitating the rapid evaluation of the essentiality of these targets on a genomic scale. In 2015, a group of researchers established the International Conference on Antibiotic Resistance (IC2AR).The primary objective of this meeting is to bring together scientists involved in antibiotic resistance prevention and control. The IC2AR conducted its inaugural world congress in January 2015 at Caparica (Portugal). Antimicrobial resistance presents a significant challenge to scientists in the field of infectious diseases. The full knowledge of how antibiotics resistance is evolving and being transmitted between hosts in different ecosystems is taking on great importance. Necessary action includes research to define the scope of the problem including its various sources. This eBook comprises a series of original research and review articles dealing with the epidemiology of resistance in animal and zoonotic pathogens, mobile elements containing resistance genes, the omics of antimicrobial resistance, emerging antimicrobial resistance mechanisms, control of resistant infections, establishing antimicrobial use and resistance surveillance systems, and alternatives strategies to overcome the problem of antimicrobial resistance worldwide. Gilberto Igrejas, José Luis Capelo and Patrícia Poeta Scientific Committee of IC2AR, February 20th, 2017
    Keywords: QR1-502 ; Q1-390 ; Microbiology ; antimicrobial resistance ; Antibiotic surveillance ; Proteomics ; Genetics ; Infections ; Animal pathogens ; antibiotics ; Epidemiology ; One Health ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)
    Language: English
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    Evolutionary Genomics (2021)
    Springer Nature
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    Publication Date: 2024-04-05
    Description: This open access book addresses the challenge of analyzing and understanding the evolutionary dynamics of complex biological systems at the genomic level, and elaborates on some promising strategies that would bring us closer to uncovering of the vital relationships between genotype and phenotype. After a few educational primers, the book continues with sections on sequence homology and alignment, phylogenetic methods to study genome evolution, methodologies for evaluating selective pressures on genomic sequences as well as genomic evolution in light of protein domain architecture and transposable elements, population genomics and other omics, and discussions of current bottlenecks in handling and analyzing genomic data. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detail and expert implementation advice that lead to the best results. Authoritative and comprehensive, Evolutionary Genomics: Statistical and Computational Methods, Second Edition aims to serve both novices in biology with strong statistics and computational skills, and molecular biologists with a good grasp of standard mathematical concepts, in moving this important field of study forward.
    Keywords: Life sciences ; Bioinformatics ; Genetics ; Evolutionary biology ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAJ Evolution ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical) ; thema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biology
    Language: English
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