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  • Articles  (8)
  • Articles: DFG German National Licenses  (8)
  • Latest Papers from Table of Contents or Articles in Press
  • Adenohypophysis  (8)
  • Springer  (8)
  • American Chemical Society (ACS)
  • Cambridge University Press
  • Nature Publishing Group
  • 2020-2024
  • 2015-2019
  • 1985-1989
  • 1980-1984
  • 1970-1974  (8)
  • 1965-1969
  • 1935-1939
  • 2021
  • 1973  (8)
  • Medicine  (8)
  • Economics
  • Natural Sciences in General
  • Process Engineering, Biotechnology, Nutrition Technology
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  • Articles  (8)
Source
  • Articles: DFG German National Licenses  (8)
  • Latest Papers from Table of Contents or Articles in Press
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  • Springer  (8)
  • American Chemical Society (ACS)
  • Cambridge University Press
  • Nature Publishing Group
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  • 2020-2024
  • 2015-2019
  • 1985-1989
  • 1980-1984
  • 1970-1974  (8)
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  • Medicine  (8)
  • Economics
  • Natural Sciences in General
  • Process Engineering, Biotechnology, Nutrition Technology
  • Biology  (8)
  • 1
    Electronic Resource
    Electronic Resource
    Secretory surface phenomena in freeze-etched preparations of the adenohypophysical cells and neurosecretory fibers (1973)
    Springer
    Cell & tissue research 136 (1973), S. 207-214 
    Details
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Neurohypophysis ; Exocytosis ; Freeze-etching
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The freeze-etching technique was used in studies of cell surface phenomena during the release of secretory products from the adenohypophysis and from neurosecretory terminals of rats in which exocytosis had been stimulated by the administration of hypothalamic extracts (somatotrophs, thyrotrophs, gonadotrophs and mammotrophs) or severe hemorrhage (neurohypophysis). The observations suggest that secretory granules are extruded through an opening at the tip of a protrusion of the cellular surface. The protrusions seem to result from the abutting of secretory granules on the inner surface of the plasma membrane. These structural details revealed in freeze-etched preparations have not been seen previously in conventional micrographs of ultrathin sections and may provide a clue to the mechanism of secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307441
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  • 2
    Electronic Resource
    Electronic Resource
    Cytodifferentiation of the adenohypophysis of the domestic fowl (1973)
    Springer
    Cell & tissue research 138 (1973), S. 299-314 
    Details
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Chicken ; Cytogenesis ; Fine structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the chick embryo the first membrane-bound secretory granules occur in the cytoplasm of occasional cells in the cephalic lobe of pars distalis at the 7th day of incubation. On the 8th day most of the cells in both the cephalic and caudal lobes contain secretory granules that are variable in size, form and density. On the 9th day at least two types of glandular cells are distinguishable in the cephalic and in the caudal lobes; however, these cells are not comparable with those of the adult gland. Differentiation of acidophils and basophils occurs, apparently simultaneously, in 11-day embryos. The cells of the cephalic and caudal lobes are morphologically distinct from their first appearance. Thus it is concluded that these two lobes develop independently and differently from an early stage of ontogenesis. The secretory granules are formed in the Golgi area of the hypophysial cells after the 8th day of incubation. However, secretory material may be synthesized also by a process not involving the Golgi apparatus. Nerve fibers containing granules first appear in the superficial layer of the median eminence on the 8th embryonic day and by the 12th day three types of granules and two types of clear vesicles are identifiable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307094
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  • 3
    Electronic Resource
    Electronic Resource
    Modifications des cellules gonadotropes de la préhypophyse chez la ratte injectée de testostérone au cours du cycle oestral (1973)
    Springer
    Cell & tissue research 138 (1973), S. 63-73 
    Details
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Rat ; Gonadotrophic cells ; Cycle, influence of testosterone ; Light microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 4-day cyclic adult female Wistar rats were injected subcutaneously with testosterone propionate on diestrus 1 at 16:00 and on diestrus 2 at 10:00 respectively. Non-injected females served as controls. Autopsy was performed on diestrus 2 at 23:00, and on proestrus at 14:00 and 17:00 respectively. The blue Alcian-PAS staining was used to evidence FSH (β) and LH (γ) pituitary cells. In control animals and in diestrus 2 injected females only a small number of FSH cells could be detected on diestrus 2 at 23:00. This number increased markedly on proestrus at 14:00 and decreased on proestrus at 17:00. A similar evolution was observed in diestrus 1 testosterone injected females, but the number of FSH cells appeared higher at any stage of autopsy in these females than in diestrus 2 injected females and in control rats. In control females, numerous LH cells were observed on diestrus 2 at 23:00. The number of these cells was diminished on proestrus at 14:00 and still more at 17:00. On the contrary few LH cells were detected in testosterone injected females on the evening of diestrus 2. An increase of these cells occurred on proestrus at 14:00, followed at 17:00 by only a weak diminution as established by comparison with control animals. An inhibition of FSH release and a suppression of the proestrus surge of LH were therefore supposed to cause, on one hand, the slowing up of follicular growth observed in diestrus 1 injected females and, on the other hand, the blockage of ovulation noted in both diestrus 1 and diestrus 2 treated animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307078
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  • 4
    Electronic Resource
    Electronic Resource
    The prolactin cell of the white-crowned sparrow,Zonotrichia leucophrys pugetensis (1973)
    Springer
    Cell & tissue research 138 (1973), S. 455-474 
    Details
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Bird ; Prolactin cell ; Reproduction ; Fine structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The anterior pituitaries from a series of female White-crowned Sparrows,Zonotrichia leucophrys pugetensis, in the periods of oviposition, incubation, and brooding under natural conditions, have been investigated by electron microscopy. The prolactin cells occur in cephalic lobe and are characterized by large (ca. 300–600 mμ), polymorphic electron-dense secretory granules and an extremely well developed, lamellated endoplasmic reticulum. During incubation and brooding it is only these prolactin cells that are in an activated secretory phase, as indicated by increase in number and size, extremely well developed endoplasmic reticulum, decrease in number of mature secretory granules, and by active formation of granules in the enlarged Golgi apparatus. In the late stages of brooding, and post-breeding, the prolactin cells regress with involution of the endoplasmic reticulum and Golgi apparatus, reaccumulation of granules, and the appearance of lysosomes. The gonadotropes of both the cephalic and caudal lobes undergo progressive morphologic changes through the course of the breeding period. They are numerous and active in the ovulating bird. They undergo gradual regression during the periods of incubation and brooding to become typical “broody” cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572290
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  • 5
    Electronic Resource
    Electronic Resource
    Influence de la méthode de fixation sur l'observation des divisions cellulaires dans l'adénohypophyse du rat mâle (1973)
    Springer
    Cell & tissue research 143 (1973), S. 535-547 
    Details
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Rat ; Mitoses, topographic distribution ; Influence of fixation ; Light microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Résumé Les mitoses de l'adénohypophyse du rat mâle ont été examinées comparativement après fixation par perfusion et après fixation par immersion. Après fixation par perfusion la répartition topographique des mitoses dans le parenchyme est homogène, et l'index mitotique est de 1,85 pour 1 000 cellules. Après fixation par immersion, la densité des mitoses décroit de la périphérie vers le centre, et l'index mitotique n'est que de 0,80 mitoses pour 1 000 cellules. La lenteur de pénétration du fixateur pendant l'immersion est tenue pour principal responsable des différences observées. Elle entraîne une modification de l'aspect des mitoses, telle que plus de la moitié d'entre elles ne sont pas identifiables et échappent aux comptages.
    Notes: Summary The mitoses of the adenohypophysis in male rats have been observed comparatively after fixation by perfusion and fixation by immersion. After fixation by perfusion, the topographic distribution of mitoses throughout the parenchyma is homogenous and the mitotic index is 1.85 for 1 000 cells. After fixation by immersion, the density of the mitoses is decreasing from the periphery towards the center and the mitotic index is only 0.80 for 1 000 cells. The slow penetration of the fixative during fixation by immersion is considered to be the main cause in the differences observed. This slow action causes a modification in the aspect of the mitoses, and more than fifty percent of them cannot be identified and escape to the counts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306772
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  • 6
    Electronic Resource
    Electronic Resource
    Fine structure of the adenohypophysis in immature sockeye salmon, Oncorhynchus nerka (1973)
    Springer
    Cell & tissue research 140 (1973), S. 459-471 
    Details
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Sockeye salmon ; Cell types ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ultrastructure of the secretory cells of the adenohypophysis of juvenile sockeye salmon was investigated. Pituitary glands were collected from immature fish transferred experimentally to sea water and subsequently returned to fresh water. The rostral pars distalis contained three cell types: ACTH cells, prolactin cells, and non-secretory cells. The prolactin and non-secretory cells were joined together in the form of follicles by desmosomes and they both had cilia and microvilli projecting into the follicle lumen. Various follicular structures such as lumen, multivesicular structures, and peripheral basement membrane are discussed as possible sites of prolactin cell granule release. The columnar ACTH cells were found at the junction of the rostral pars distalis and the neurohypophysis. The cytoplasmic granules in these cells were characteristically separated from their limiting membrane by a clear space. Multivesicular structures were also found in association with this cell type. The caudal pars distalis also contained three cell types: one acidophil (putative somatotrop) and two basophils (putative thyrotrops and gonadotrops), all of which were similar to those described in adult fish. The pars intermedia contained only one cell type. They appeared to be active cells and were characterized by containing membrane-bounded granules similar to those found in the ACTH cells. Changes in ambient salinity had no apparent effect on any cell type described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00306673
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  • 7
    Electronic Resource
    Electronic Resource
    Responses of prolactin cells of two euryhaline marine fishes, Gillichthys mirabilis and Platichthys stellatus, to environmental salinity (1973)
    Springer
    Cell & tissue research 136 (1973), S. 153-167 
    Details
    ISSN: 1432-0878
    Keywords: Prolactin ; Adenohypophysis ; Osmoregulation ; Teleosts ; Light and electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Changes in the prolactin cells of the euryhaline marine teleosts Gillichthys mirabilis and Platichthys stellatus were studied by light and electron microscopy after transfer from sea water to fresh water. In seawater fish the secretory granules were smaller and the cellular organelles poorly developed. Within 3 hours after transfer to fresh water, the prolactin cells of Gillichthys exhibited definite functional activation: exocytosis of granules and development of rough endoplasmic reticulum (RER), Golgi systems and mitochondria. Concurrently, plasma sodium fell from about 172 meq/l to about 133 meq/l. As adaptation to fresh water progressed, prolactin cells of Gillichthys showed greater prominence of cellular organelles but granule storage was not detected even 10 days after transfer. Platichthys adapted to fresh water for 10 days showed RER in an expanded state containing irregular electron-dense material which was not seen in Gillichthys. Plasma sodium levels were much lower than in the controls. These results were in contrast to those obtained from euryhaline freshwater fishes such as Poecilia and Oryzias. Although the prolactin cells of euryhaline marine fish exhibited intense secretory activity when transferred into fresh water, the secreted prolactin per se appeared to be insufficient to maintain plasma sodium at seawater levels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307436
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  • 8
    Electronic Resource
    Electronic Resource
    The rostral pars distalis of the pituitary gland of the freshwater and marine alewife (Alosa pseudoharengus) (1973)
    Springer
    Cell & tissue research 141 (1973), S. 145-159 
    Details
    ISSN: 1432-0878
    Keywords: Adenohypophysis ; Alewife ; Salinity ; Release of hormones ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the alewife the orohypophyseal duct, a remnant of Rathke's pouch, persists in adults as a tube passing from the rostral pars distalis to the pharyngeal region. Its lumen is not open to the buccal cavity. The prolactin cells are situated around the bifurcations of this duct in the rostral pars distalis. Contents from prolactin cells, such as granules, nuclei, mitochondria and Golgi structures were found in these bifurcations. These contents were indistinguishable from those of intact prolactin cells. Evidence of actual release into the duct was often noted. At the presumptive point of release, the cells lining the lumen separate and the contents, probably of an entire prolactin cell, are extruded. The cilia usually found at the point of extrusion arise from prolactin cells. The prolactin cells of freshwater fish were more heavily granulated than those from a marine environment. Prolactin cells of fish entering freshwater streams were not heavily granulated but showed evidence of increased activity. Granule size was not affected by salinity. The ACTH cells are arranged in bands along branches of the neurohypophysis in the rostral pars distalis. No differences in ACTH cells from fish of different salinities were noted.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00311351
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