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  • Articles  (87)
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  • Articles: DFG German National Licenses  (87)
  • Latest Papers from Table of Contents or Articles in Press
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  • Springer  (87)
  • American Chemical Society (ACS)
  • American Society of Hematology
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 43 (1987), S. 39-48 
    ISSN: 1420-9071
    Keywords: Weather ; cognitive processes ; sympathetic ; psychopathology ; emotion or mood ; brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Research concerning the complex relation between weather and psychological processes has emphasized three important issues: methodological problems, the determination of the major behavioral factors, and the isolation of neurobiological mechanisms. This paper reviews the current status of each issue. Weather changes are most frequently associated with behaviors that are the endpoints of inferred psychological processes that include mood, subclinical pain, anxiety, and the correlates of schedule shifts. Learning and conditioning appear to mediate a powerful influence over weather-related responses. This may explain the large individual variability in these behaviors. The most well-known group effects associated with weather changes involve psychiatric populations. Clinical subpopulations may respond in different ways to different aspects of the same weather system as well as to different types of air masses. Likely neurobiological mechanisms through which meteorogenic stimuli may mediate whole organismic effects include the locus coeruleal and limbic systems. Expected psychobiological consequences are examined in detail. The magnitude and temporal-spatial characteristics of weather effects indicate they are the subject matter of behavioral epidemiology.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 43 (1987), S. 188-190 
    ISSN: 1420-9071
    Keywords: Luteinizing hormone ; immunocytochemistry ; brain ; white-footed mouse
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of immunoreactive LH in the brain of the white-footed mouse (Peromyscus leucopus) was determined using immunocytochemical procedures. Immunoreactive fibers are located in the hypothalamus, preoptic area, septum and amygdala. Stained cell bodies are seen in the arcuate nucleus and preoptic area. Gonadectomy enhances staining for LH in the brain.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 759-769 
    ISSN: 1420-9071
    Keywords: Alpha-fetoproteins ; androgens ; brain ; estrogens ; estrogen antagonists ; estrogen receptors ; genitalia ; gonads ; hypothalamus ; preoptic area ; receptor imprinting ; reproductive tract ; sexual differentiation ; sexually dimorphic nucleus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 820-821 
    ISSN: 1420-9071
    Keywords: Polyamines ; methylthioadenosine ; methylthioadenosinephosphorylase ; brain ; regional distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of 5′-deoxy-5′-methylthioadenosine (MTA) phosphorylase in 10 pig brain areas was determined. The observed regional differences of the enzymatic activity seem to reflect more the pattern of brain spermine distribution rather than that of spermidine. Moreover, comparative studies on the heat-resistance of MTA phosphorylase extracted from the whole brain of various species suggest structural differences in the enzyme molecules occurring in the brains of different animals.
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 43 (1987), S. 403-405 
    ISSN: 1420-9071
    Keywords: SHR ; cyclosporin ; immune mechanisms ; hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In spontaneously hypertensive rats the effect of the T-cell inhibitor cyclosporin was studied at different ages. If treatment was started at the age of 2 weeks the development of hypertension was delayed, but the ultimate level of blood pressure was not affected. These results indicate the involvement of immune mechanisms in the early development of hypertension in spontaneously hypertensive rats.
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 43 (1987), S. 413-415 
    ISSN: 1420-9071
    Keywords: Δ1-tetrahydrocannabinol (Δ1-THC) ; cannabidiol ; beta-endorphin ; plasma ; brain ; hypothalamus ; hippocampus ; rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Acute treatment with Δ1-tetrahydrocannabinol (Δ1-THC) elevated the concentration of β-endorphin-like immunoreactivity (β-ELIR) in plasma and in the hypothalamus, but not in the hippocampus of rats habituated to the injection procedure. These effects were not obtained with the psychotropically inert analog of (Δ1-THC), cannabidiol. In animals that had not been habituated to the injection procedure, placebo treatment induced a decrease in hippocampal β-ELIR.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 43 (1987), S. 750-761 
    ISSN: 1420-9071
    Keywords: Receptors ; multiplicity ; radioligand binding ; quantitative autoradiography ; light- and electron microscopy ; peptidases ; endogenous ligands ; brain ; gut
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The receptors for regulatory peptides have been extensively characterized using radioligand binding techniques. By combining these binding techniques with autoradiography it is possible to visualize at the light and electron microscopic levels the anatomical and cellular localization of these receptors. In this review we discuss the procedures used to label peptide receptors for autoradiography and the peculiarities of peptides as ligands. The utilization of autoradiography in mapping peptide receptors in brain and peripheral tissues, some of the new insights revealed by these studies particularly the problem of ‘mismatch’ between endogenous peptides and receptors, the existence of multiple receptors for a given peptide family and the use of peptide receptor autoradiography in human tissues are also reviewed.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 1240-1241 
    ISSN: 1420-9071
    Keywords: Cholecystokinin ; radioimmunoassay ; species difference ; molecular heterogeneity ; brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ratio between large and small carboxy-terminal forms of cholecystokinin in brain extracts from man, pig, dog, rat, chicken, frog and trout was determined by two sequence-specific radioimmunoassays. It was found that the relative amounts of large forms of cholecystokinin; are higher in mammalian brain than in brains of lower species.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 1027-1028 
    ISSN: 1420-9071
    Keywords: 18-OH-DOC ; brain ; excitability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of 18-hydroxydeoxycorticosterone (18-OH-DOC) on central nervous system excitability were studied in adrenalectomized rats. Sixty-four evoked potentials (EP) recorded from the pontine reticular formation were averaged before and after the injection of vehicle and hormone. 750 μg of 18-OH-DOC dissolved in 0.5 ml of a 4∶1 saline Cremophor-EL solution were injected i.v. A decrease of 55.7±6.1% in the amplitude of the EPs was observed with the hormone 16.3 min±2.7 (SE) after injection. Amplitude values returned to baseline levels 38 min±6.8 (SE) after injection. The secretion of 18-OH-DOC is greatly increased by ACTH and might modulate central nervous system function.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 1238-1239 
    ISSN: 1420-9071
    Keywords: Kinins ; bradykinin ; kallidin ; cerebrospinal fluid ; HPLC ; hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Rat cerebrospinal fluid contains peptides which displace radiolabeled bradykinin from its specific antibodies. Two peptides which showed the same retention time as kallidin and bradykinin in a reverse phase high pressure liquid chromatography system were detected in cerebrospinal fluid of rats. The concentration of radioimmunologically detected kinins in the cerebrospinal fluid of spontaneously hypertensive rats of the Okamoto strain was lower than that of the Wistar Kyoto control rats.
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